LOCUS       gnlProkkaCMHMDIMF_29   14254 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CMHMDIMF_29.
ACCESSION   gnlProkkaCMHMDIMF_29
VERSION     gnlProkkaCMHMDIMF_29
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 13:13:23
            Original ID  :: gnl|Prokka|CMHMDIMF_29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9634
            Orig. end    :: 23888
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14254
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14254
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2484..3161
                     /locus_tag="ctg29_10"
                     /transl_table=11
                     /translation="MTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLD
                     EVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAEL
                     MPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVN
                     LIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKN
                     NES"
     CDS             3180..4220
                     /locus_tag="ctg29_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             4225..5319
                     /locus_tag="ctg29_12"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5329..6570
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg29_13"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(6590..7054)
                     /locus_tag="ctg29_14"
                     /transl_table=11
                     /translation="MVGDLFRHFSNQSVLYGSQQLARVVGTERRKLLFKVFGMIGVVDK
                     THIDGDSQLRLRRVTVGRYCLVVLIVTCDFSVNLQVSILIRLEQLQTGLPDEDIFQVFI
                     KFGCQRSIYILRLDREVGYRNGLYLIIIDRRSVKLIGNSARNDYQRQAEQ"
     CDS             7090..7863
                     /locus_tag="ctg29_15"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQLAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             8050..8265
                     /locus_tag="ctg29_16"
                     /transl_table=11
                     /translation="MVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAPQ
                     TEAPATNAPATETPAPATETPAPAAE"
     CDS             8593..9903
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 85.1; E-value: 6.2e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg29_17"
                     /transl_table=11
                     /translation="MLCGYFLTDVMSPLKPMLEKELLWDSLDYGFFTSAYGWFNVFLLM
                     LIFGGIILDKMGVRFTGMGACLLMVFGCGLKYYAISTTFPEGAMLFGFKTQVTLAALGY
                     AIFGVGVEIAGITVSKIIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPLADFFGSM
                     DESGTFHTNIPAPILFCLIMLCVGTIAFFLYTFYDKKLDASLDAEGLEPEEPFRMKDIV
                     YIITNKGFWLIALLCVLFYSAVFPFIKYAADLMVQKYNVDPKLAGTIPGLLPIGAIILT
                     PLFGSLYDRIGKGATLMIIGSVMLIFVHTMFALPILNIWWFATIIMIILGFAFSLVPSA
                     MWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVPLLIGWVLNTYCKGPVVDGAQTYDYTL
                     PMAIFALFGVLALIVALMLKAENKKKGYGLEEANIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_18"
                     /sec_met_domain="PqqD_RRE (E-value: 1.6e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.7e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10370..10654)
                     /locus_tag="ctg29_19"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10691..11791)
                     /locus_tag="ctg29_20"
                     /transl_table=11
                     /translation="MFSKPVKKEPNMKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGV
                     VYSLPKTQIELEIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVP
                     NSETTYFVKLKDKTVAPLMELTEDGIVKTINVPYSNSSAGKKAAPAPAVLQKKANPREF
                     LTEEILMASSTAKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEE
                     AMTQMFSGTCNKEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDL
                     KSVKIPQEDGKKKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLF
                     NKNSTIKVYFDPNTGGLLKVDREEGK"
     CDS             complement(11832..13343)
                     /locus_tag="ctg29_21"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYLT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
ORIGIN
        1 cgcccatttc cagttgaatg gtttttcaca ggcggatgcc aagtcgttct caaagcagta
       61 tttgtctact tactccaagg ctttgtccgc acaacaggaa gatattcttg cttcgtgggt
      121 gctggctaaa caaccgcgct gtttaagtgt attgctcaac gagctggttt cgttcggtca
      181 gtacgatgct ctcaatgaat atatgagtgg atattgccgg ctcaatgagg ttgggcaatt
      241 ctatgacagt gtgttacggc gtttgtcggc tgattatggt ttcgaagaga ttggaagaac
      301 gcttctgatg ctttcactta ctttagaagg atttaccgaa gatgaagtga agagcatggc
      361 agacattaat cagatacttt ggtcgcagtt gagagtggaa atgagcagct ggcttaccaa
      421 caaaggagga cgatattgca ttggtgacac acaaatggta gaggcaatcg aacgctattt
      481 cgctcaagat gacgaatgta tagatgatag tcgccatgaa attatttccg ctttgctgga
      541 tgaggaagag attctttccc atccgttgac ttttgccgat tataactatc gcatgaaaca
      601 gttctgctac catgattcgt atcgctataa agtggagatt acctatcaat gctataagat
      661 gcaagaatgg gatatattga aggattggat ttgtgatgtg gagattttcg agattctgta
      721 tcgcacgaat cgttctctgt tggaagatag ctggaaggcg atcatgaacg acaatcctga
      781 agttacgcct gaagtctatg ccgaattgga ctttgatgag atcgattctt ttttaattcc
      841 tgtcattgct aatgatatgg ctactttctt gagcagttct ttccatctga cgaaggcggc
      901 agctgctgtg agtgagaaga gtatggaagg tgctgccatg ccactcattg ccaagtcggt
      961 attgaagatg aatgagggat gccggtatgc ccgtaatgaa gaatacgaaa cggcatgcga
     1021 ctgtttcctg aaagcattgg tgatgcagga aaacattgta ccgactccgg aactggagat
     1081 tgccaacacc tgccgaaatc tagctctggc atattactac aatgagcaat acaatgaagc
     1141 agtgacctat ttgaataggg cgcttgatta tcatgcggct tctgctgacg agaagagtca
     1201 ggcagaagtc attgaacttt ccgaatatct ggcttattgt gattactata aggatgagga
     1261 agagagtgct gccgagaaat tccggaaagt agctgaaatg cacgagtcgt tgaatggcag
     1321 actgtctggt ggagtggcta aatgtttgcg tatgcagggt aaatgtcttt attatatcaa
     1381 acgatacgat gaagcatgga tgctgatgaa tcaggcgttg gacattgcta tacagataga
     1441 cagcaaaaaa cagatcgtcg cttgtcataa acagttgtat tatctatgca gggaattcaa
     1501 gcggatgatg aatgaacgtg gcgatgagca ggcgtctact ttattcttcc gtgagtctct
     1561 tctgcatgaa atgtatttca gcgaaaaacc gcgtctggcg gaactgactg tccgctacga
     1621 ggcattgaga tgtgatatta tgcagcagta ttacatgaat aaagactatg ataacgtgat
     1681 tcgtattgca acgtctttgg attttcacga tgatactgac cttaatgctt cctgtctggt
     1741 atattattac aaagcacagg cttatgtgaa gttggagaat tatccaatgg cgaaagaggc
     1801 tttcttcaga gagtttgaac tgcgaaagaa atatctggga tgggaggatg aagatacgat
     1861 tctggcttgt cagaacctag gggttttgca cagcttttgt aatgaacggg aagaggcgct
     1921 ggcttgtttc cgtgaggcgt acggtcatga agtgaaaaag aatggcgagg attctgaaat
     1981 ggcgcaaaag ctacttcaat atatcagcgt ggttgaatca taacggaggc atacttccct
     2041 tttttgttaa cttttacatt cctgctatac ggaaatcgac tttatttcct tacatttgca
     2101 gatataaact atcaatagaa agaagaatgt ctaaatatcc ccttttagga atgactcttg
     2161 tagagcttca atcattgaca aaaagactgg gtatgcccgg ctttgctgcc aagcagattg
     2221 catcctggct ttacgaaaag aaggtagcct cgattgatga tatgactaat ttgtcattga
     2281 aacaccggga gttgctcaag cagaactatg aggtgggagc ggaagctccg gtagatgaaa
     2341 tgcgctctgt agatggtacg gtgaagtatc tttataaagt gggtgagaac cattttgtag
     2401 agtcggttta tataccggat gatgaccggg caacattgtg cgtgtcgtca caagtaggtt
     2461 gcaagatgaa ctgtaagttc tgtatgaccg gtaaacaggg gtatacagct aacctgaccg
     2521 ccagccagat cataaaccag attcattcgc tgccggaacg ggataaactg actaatgtcg
     2581 taatgatggg aatgggcgag ccgctcgata acctggatga ggtattgaaa gcattggaac
     2641 tactgaccgc tacctacggt tacgcatgga gtccgaagcg tatcacgctt tctactgtcg
     2701 ggctacggaa aggattgcag cgttttatcg aagaaaatga ctgccacctt gccatcagcc
     2761 ttcactctcc gctgaccgtt cagcgtgctg aattaatgcc ggcggaaaag gcgttttcaa
     2821 tcaccgaaat ggtggaactg ttaaaaaact atgattttag taaacaacgt cgactttcgt
     2881 ttgaatatat tgtttttaaa gggctcaatg attcgcaggt ctatgccaaa gagttgctga
     2941 aacttcttcg cgggctggat tgcagggtga atctgattcg ttttcatgcc ataccggggg
     3001 tagacctcga gggggcggat atggatacga tgacccgttt tcgtgattat ctgacgtcac
     3061 acggactttt caccactatc cgttcatcca ggggcgaaga tatttttgcc gcttgcggta
     3121 tgctgtcgac agcgaaacag gagaaaaata atgaaagtta atatataaaa ccgaacatca
     3181 tgaaaaagta ctcttttatt ttatgcatcg ctttggtagc ctttgtcgtt gcatcttgtg
     3241 gtctgaaagg aaatcacacc tctagtggtc gtgcttacga gcttttggtt gtagtagatc
     3301 acggtgtttg ggatcgtgct gccggaaggg ctttacatga tgcgctcgat gctgatatgc
     3361 ccggtttgcc gcagtcggaa ccttctttcc ggattatgta tacttcgccg aaagattatg
     3421 attctacgct gaagttgata cgtaacatta ttattgtaga tatacaggat atatatacga
     3481 aagcctcgtt caaatatgcg aaggacgtgt atgccaatcc gcagatgata ttgactatcc
     3541 aggctccgaa cgaagaagag tttgagaagt ttgtggaaga gaacaaaaag acgattgtcg
     3601 acttctttac ccgtgcggag atgaaccgtc agattacgtt cctggaaggg aaacacagta
     3661 atttcatttc gcagaaagtg gacagtttgt tcggatgcga catctgggtg gatgccgaac
     3721 tggctaattc aaagaccggg gatgatttct tctgggcttc taccaacaca ggtactgccg
     3781 accgtaactt tgtgatgtac tcttatccgt acactgacaa ggatacgttt accaaagaat
     3841 attttgtgca caaacgtgac tccgtgatga aagccaatat tcccggattc aaggagggcg
     3901 tttatatgtc gaccgatagt ttgctgaccg atgtccgtcc gatcaatgtg cagaacagct
     3961 acacaatgga agcacgtggt ctgtggcgta tgaagggcga ctttatgggt ggtccgtatg
     4021 tctctcacac tcgtctggac gagaaaaacc aacgaattat tacagcagaa atatttgttt
     4081 attcacctga taaaatgaaa cgcaacctgg tacgccagat ggaagcatct ctgtatacac
     4141 tgaaacttcc gaatgaagtt cagcagaatc agattccatt gggagaggca tctaaggaag
     4201 cggaacaaac taataaataa aaacatggaa gataacaaga taaggatagg tatcacccaa
     4261 ggagatatta atggggtggg ctatgaggtg attcttaaga cattttccga ccctacaatg
     4321 ttggaactat gtactccgat catttatggc tcaccgaaag tagcggctta tcatcgcaaa
     4381 gcgctggata tacaggccaa ttttagcatt gtcaactctg ctaccgaagc ggggtacaac
     4441 cgtttgagcg tggtgaactg tacggatgat gaggtgaaag tggaattttc caaacccgac
     4501 cccgaagccg gtaaagctgc gctgggggcc ttggaacgtg ccatcgaaga atatcgcgaa
     4561 gggttgatag atgttatcgt aacggctccg atcaacaaac atacgattca gtcggaagag
     4621 ttctccttcc ccggacatac ggaatatatc gaagaacgtc tgggcaatgg tgataagtca
     4681 ttgatgattt tgatgaagaa tgacttccgg gtggctttgg ttacgacaca tatccctgtc
     4741 agagagatcg cgactacgat taccaaagaa ctgattcagg agaaactgat gatattccat
     4801 cgttgtctga aacaggattt cggtatcggc gctccgcgta ttgcggtgct ctctctcaat
     4861 cctcatgccg gagacggtgg tctgttggga atggaagagc aggaagtgat tatccctgcc
     4921 atgaaagaaa tggaagaaaa aggaatcctt tgctacggtc cttatgcggc cgacggcttt
     4981 atgggttcgg gcaattatac tcattttgac ggtatcctgg cgatgtatca cgatcagggg
     5041 ctggctccgt tcaaggcctt ggctatggaa gacggggtga actatacggc aggcctgccg
     5101 gtagtacgta cttctccggc tcatggaacg gcatacgata ttgcaggcaa gggagtggct
     5161 tgtgaagatt ctttccgtca ggcaatctat gttgccatcg atgtgttccg taatcgtcag
     5221 cgggaaaaag tggctcgtgc caatccgttg cgtaaacagt attacgagaa acgtgacgat
     5281 agtgataaac tgaagctgga tacagtagac gaagattaaa aacgagtgat gacgagagca
     5341 gagatacaac aagtgaaaca gcgtttcggt attattggaa ataccgaagc attgtcgcgc
     5401 gccatagatg ttgccattca ggtagctcct accgatttgt ctgtgctgat taccggagaa
     5461 agtggagtcg gaaaagaaag ttttccgcag attattcatc aatatagccg gaggaagcat
     5521 ggacagtata ttgctgtcaa ctgtggtgct attccggagg gcacgattga ttccgaactg
     5581 ttcgggcatg agaagggtgc gtttaccggt gcgattggcg aacggaaagg gtactttggc
     5641 gaagccgacg gtggtactat tttccttgat gaagtagggg agttgccgat gcctacccag
     5701 gcgcgtttgc tccgtgtgtt ggagagtggc gagtttataa aagtaggttc gtccaaagtg
     5761 caaaagacgg atgttcgtat tgtggcagct accaatgtca atctgacaca agcgattgca
     5821 gaaggacgtt tccgtgaaga tttatattac cggttgaata cggtgcctat ccaaataccg
     5881 cctttgcgtg aacgtggtga cgatgtactt ttgttgttcc gtaagttttc cgcagacttt
     5941 gcagagaaat accggatgcc tgctattcag ttgacggagg atgcgaagaa agagttgttg
     6001 gcttacccgt ggcccggaaa tgtgcgccag ttgaagaaca tcaccgagca aatatctatc
     6061 attgaaacca atagggagat ctctgctgct atcttgcaga attatcttcc cgcacaaaat
     6121 acgcaacgtc ttcccgcgct gatgggaacg cgtgagagta aaggctttga gagcgaacgg
     6181 gagattcttt attccgttct gttcgatatg cgccaggaag tggcggagct gaagaagatg
     6241 gtgcacaacc tgatggcgga acgtgccgga caggtggggc aggtaggaca aatgggaacg
     6301 gtggttacta ctccggtagt gacggcgcat caaccttcgg tacctgctat cattcacacc
     6361 atgcagccca cggtttgcaa ggatgatgat gacatacaag acacggaaga atatgtagaa
     6421 gaatctcctt tgtcactgga tgaagtggag aaagaaatga tacgcaaagc acttgagagg
     6481 catcatggaa agcggaagag tgcggccaag gacttgaata tttccgagcg tacactttat
     6541 agaaaaataa aagaatatga attggattaa gaaaataata cgccctttgt tactgttcgg
     6601 cttgccgttg gtagtcattg cgtgcactgt ttcctataag tttaacggat cgtctatcaa
     6661 ttatgataag gtaaagacca tttcgatagc cgacttcccg atcaagtcgg agtatgtata
     6721 tgctccgttg gcaaccaaat ttaatgaaga cctgaaagat atcttcatcc ggcagacccg
     6781 tctgcaactg ctcaagccga atcagaatgc tgacttgcag attgacggag aaatcacagg
     6841 ttacaatcag tacaaccagg cagtatctgc cgacggttac tcttcggaga cgaagttgac
     6901 tatcaccgtc aatgtgcgtt ttgtcaacaa caccaatcat gccgaagact ttgaacaaca
     6961 gttttctgcg ttccgtacct acgactctag ccagttgctg actgccgtac aggacggatt
     7021 gattgctgaa atgtctaaag agatcaccga ccaaattttt aatgcaactg tagcaaactg
     7081 gtaatataaa tgacttctgt taactttcaa caatggattc agcatcccga gacgctgaat
     7141 agggatactt tgtacgaact gcgcaatctt cttgcgaggt atccgtattt tcagtcactt
     7201 cgtctgctgt atctgaagaa tctgtatatt ctccatgata ttagttttgg tggagaactg
     7261 cggaaagcag ttctttacat tgcagacaga cggcagttgt tccggttgat tgaaggtgac
     7321 cgctatgatg tgcaggcacg aaaaaaggga gtacctctca cggaggtgct gaaagacgaa
     7381 ccgtccgtag accgcacatt agcattgatc gacgctttct tgtccacagt acccgaagag
     7441 gtgactgccc gcaccagctt cgactattcg atggattaca cctcttatct tttggaggag
     7501 actccggcca cggaacagct ggccgaagaa acgcccaaac tcaaaggcta cgaactgatt
     7561 gacgacttta tagaaaagag cgagagcgac tctcccctct gcaagaaacc tttaagagaa
     7621 gaaatgccat cttcgccaac ctcttcggac gaacttaccg aagaagaaac gatgaaggaa
     7681 gaagaggaag atgacagctg ttttacggaa actttggcaa aaatctatgt taaacagcaa
     7741 cgatattcaa aagctcttga aataattaaa aaattaagct tgaaatatcc aaaaaaaaat
     7801 gcttactttg cagaccaaat cagatttttg gagaaattga ttattaacgc taattcaaaa
     7861 taactaaaaa tgtacttatt attcgttatc ttaatggtta ttgcagcctt gttgatgtgt
     7921 ttcatcgtgc tgattcagaa ctcaaaagga ggcggacttg cttctggttt ctcttcatct
     7981 aacgccatca tgggcgtgcg caagactaca gattttctgg aaaaagcaac atggggctta
     8041 gctatcttca tggtggtaat gagcattgct actgcttatg tagttcctcg ctctgctgtt
     8101 gctaaagacg cagtgttgga acaggcacag aaagaacaac agactaaccc gtataactta
     8161 cccgcaggta cggctgcgcc gcaaactgaa gctcctgcta ccaatgcacc tgctacagaa
     8221 actccggcac cggctactga aactcctgct cctgcagcag agtaattcac tccgttgtca
     8281 ggtaagactt tggggtaaaa ccattaatgg gaaggtgcag acggatgctg catttctttg
     8341 atatttaagt gcggattacg cagattacac ggattttcaa tcttccgcgt ggtcagtgta
     8401 atccgcactt aactttttct tgtaaaaaca atctcttttt gatagaaaca aacgagattt
     8461 aactaccttt gttggtcgta tgaagattat taactactat ttttaaatat aacaatgaca
     8521 gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt tctagcatta
     8581 gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc tctaaaaccc
     8641 atgcttgaga aagaactact atgggacagt cttgattatg gtttcttcac aagcgcttac
     8701 gggtggttta atgtattcct attgatgctg attttcggtg gtatcatttt ggataagatg
     8761 ggagttcgtt tcaccggaat gggagcttgc ttattgatgg tgtttggttg tggattgaaa
     8821 tactatgcga tttctactac ttttccggaa ggtgccatgc tcttcggatt caaaacacag
     8881 gtaaccctgg ctgcattggg gtatgctatc ttcggtgtag gtgtggaaat tgccggtatc
     8941 acagtttcca agattatcgt gaaatggttc aagggtaagg aaatggcgtt ggctatggga
     9001 cttgaaatgg ctacggcacg tatcggaaca actctggcaa tggtgcttac ggttcctttg
     9061 gccgactttt tcggatctat ggatgagagt ggcacattcc ataccaatat tcctgctccg
     9121 attctgtttt gtctgattat gttgtgcgtg ggtacgattg ctttcttcct ttatactttc
     9181 tatgataaga agttggatgc ttctttggat gcagagggat tggaaccgga agagccgttc
     9241 cgtatgaaag atattgtgta tatcattacc aataaaggat tctggctgat tgcattacta
     9301 tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga cttgatggtg
     9361 cagaagtata atgtagatcc gaagttggcg ggaacgattc ccggattgtt gccgattggt
     9421 gcgattattc tgactccgtt gttcggctcg ctttatgacc gtattggtaa gggagccaca
     9481 ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgtttgc tctgcctata
     9541 ctgaatatat ggtggtttgc tactatcatc atgattatat tggggtttgc cttctcgttg
     9601 gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca gttgggtact
     9661 gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc tttgttgatc
     9721 ggatgggtgt tgaatactta ttgcaaaggt ccggtagtag acggtgcaca gacttatgac
     9781 tacacgttgc cgatggctat ttttgctctc tttggtgtgc ttgctctgat tgtggctttg
     9841 atgttaaagg cagagaacaa gaagaaggga tacggtctgg aagaggcgaa tatccaaaag
     9901 taactaggaa attcaatacc taaagtgaca aaggaatttt gtatcaaggt gtaaacagaa
     9961 gagtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca aagagaaaat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa gggaagggga
    10081 gacaattgtg ctctcctttc cccgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accactttca
    10261 aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgtata aataggaact tattattatt tatttgataa
    10381 atacagccca aagtatgacg gcaattgcta tcaggactcc catgataata agcgttcccc
    10441 aaacaaaata attgctgtct ttctctttct ttttctccga gtcgtggatg atacgttcca
    10501 tttcttcggg ggtggtgttg ggtagtggat aaggttcgtt tgcacggttt agatgcttca
    10561 acttatcgtt agcacgttca cgacgtaggc gggaagcttc ccgtccctct tttattcggc
    10621 gtatcatgtc gaatgcatgt ccttcaccaa ccatattctt tgttttttag aagttcactt
    10681 cctcgttttt ctatttccct tcttctctgt ccactttgag caatcctccc gtattcggat
    10741 caaaataaac tttgatggta gaattcttgt tgaacaaaac cggagccaga tattctatca
    10801 caccgaattg ggtaatagga agctcacctt cgtaaagttt ctttttaccg tcggtcagtg
    10861 taaccatagc ttgtccgggt acgttgtagg cgattccatc caaatctttc ttcttcttac
    10921 cgtcttcctg tggtatcttg accgatttca ggtctttcag actgatataa aacggagttc
    10981 ctgccaaatc attgttggca actacaccta acttcttcga gaagcggaag gcaacttcat
    11041 tgttgaattc cttgtcaggg gtaaggcgga cagtgaatgt tctctcttct ttgttgcagg
    11101 tgccggagaa catttgtgtc atggcttctt cctgtgcatt cagattgtcg agcataatct
    11161 taagctgtgc cccatctgaa ggcatattat cagcttgtcc gcgcaataag gcatttttgc
    11221 tttcgcggat gttatagatt tctttagcca ccagctcggc catcttggcg gtagaactag
    11281 ccatcagaat ctcttcggtc aggaattcgc gaggattcgc tttcttttgg aggactgcgg
    11341 gggcgggagc agcttttttg cctgcactgc tattgctgta aggaacattg atcgttttca
    11401 caatgccatc ctctgtcagt tccatgagcg gtgctactgt cttatccttc aattttacga
    11461 aatacgtagt ttcgctgttg ggcacaccta cggatttcac ttttacgcta gccagttccc
    11521 agtactcttc agggtcggcg gagacgttgg tcagtcgtag gtaacgatca gcatatttgc
    11581 tgaattctcc cggagtatag ttgactttgt tggcttttat ttcaagttct atttgggttt
    11641 tgggaagact gtaaaccact ccatagtctt ttcctcgggt aacccctgtc agtacttcgg
    11701 tttgtgcata ggcggacgtt gtcataagta gtcctgctgc tataatcaac tttttcatat
    11761 tcggttcttt tttaactggt tttgaaaaca aagttaatga agttattgaa aaaagggtaa
    11821 gttcttaact tttattcgct tacaagtcgc catgctgtcg gcagacaggt gataatatcg
    11881 cttgcgatca ttccgatcat tccttgcttc ttttgagcga catcgcccgc caatccgtga
    11941 atgtaagtgc cgattttagc ggcttcctcg gtgaggtaac cttgggcaag cagtgccagg
    12001 attactccgg tcagtacgtc accgctacct ccggttgcca ttcccggatt tccggttggg
    12061 ttgaagaagc atttaccttc tggggtgatg atggcggagt aggctccttt taaaataatg
    12121 tgaacatggg cggcacgagc caattcgcaa gccttcatca gacgttcgta agagtcctgg
    12181 catttgccgg tcagacgttc cagttctttc ggatgcgggg tgaggatgga acccttcggc
    12241 aggtgggtaa gtgcatgacg gtggttggcg aggatattaa gtgcgtcggc atccaccaca
    12301 acaggagtct ggcagtgttc cagttgttcc aacaaggcag cttccgtttc ctcgtttcgt
    12361 cccagtcccg gaccgatgcc gactgcttga tagtcgtccg tgtcggtagg tacggcaaaa
    12421 caggtttcgt tgatgtcggt ttctacgatt gcttcgggta tggaggtttg caagatgtcg
    12481 ttgttgcaca ttggcgcatg gacagtcagc aaccctactc ccgaacggag gcaggcgcgg
    12541 gcagcgagaa cagaggctcc tgccattcct tttgaaccgg caatcaatag tgcatggccg
    12601 aagtttccct tgtgggcaaa ctgtttgcgt ggcttgatga gtgaacggat ttgctctatt
    12661 tccaacattt cgtagttagt ctccatttct tcaataccgt cttcgctcaa ttggatatcc
    12721 agcacttccc attctccgac aaattccgtg ttctctgcga aaagaaaggc gagcttcggc
    12781 agttgaagac tgaaagttac gtcggcacgg ataatattag cttttacgtt gaatgtgttt
    12841 tcttctccca tcagtccgga aggaatgtcg atggctacta ccatggcagg ggaggaattg
    12901 atgtatttca ctacggcagc gaatccgccg ctcaacggtt tgttcaggcc tgaaccgaat
    12961 aatccgtcga ttaccagatg gtcgggcgtc agggcgggag gtacgaattg ggtactgatc
    13021 tcgtggaatt ttacttcttc catcatttct accagttctt tattggtctg gcagtcgggt
    13081 gaaagttctc ctttcgtgtt gaagagaaat acctcgattt tatatccttt ttcagccatc
    13141 atgcgggcta cggcgagagc gtctccgcca ttattccccg gtccggcaaa gatagtgacc
    13201 ggcgtttccg tattccatct gtctgtgatg gcttttgtta atacggttgc tgcacgttcc
    13261 atcagatcga ttgatgcaat aggttcgttc tcaatggtat aagcgtccaa tttcttgata
    13321 ctgctgcttg gaaatatttt cattgcgatg ttcttttagt tttcggatta caaatgtaca
    13381 tgattcttct gacttttccc gtttgttgtg ggaagaaaac cataattgca acttttaatt
    13441 catcattagt tctatctttt ggtcagagaa atatctgttt ttgaactatt aagtgttaga
    13501 ataactccgc caaaaaataa ttcaatgcag caccattatg aacttacttt tatttctcct
    13561 gaaaaagatt tctggttctt cgtcaaattt ggtggtaaat tctttatctc tttatttcca
    13621 agttaataat tatccctttt tactcacttt cataagaaaa tataggcact gactgaatta
    13681 gctaaatgag cggagaaaaa cttaccacca aatttgacga agaaccagat ttcttcattt
    13741 catttctcat attctcattg tttttcgata aacgaaagct aatcaaatag atatcttatg
    13801 agaaacactt tttcgaaacg gtatttctca taagttctcc catattttgg ctcaaaagcc
    13861 gccttattct catagtattt cagggtattt ctcatagtca aaagccattt gttcttcctt
    13921 ttttctttca gcctgcctta tttttatcag gaaatgaagc tactatttag ataaaatagt
    13981 ggctttttgc ttgaagatgc tcattggtct cgattgtccc atatattgtg ggaaagtttt
    14041 ccttcaatat acgggaatac tttcccacaa aataagggaa tactttccca agccttaggg
    14101 aatcttttcc cacaatatgt ggaactaaga cactgtgtat ggaagcaagc aaaaggaata
    14161 catagtttta tttattcaat gtcagcttcc ggcacacgac actatgagaa atgaagcaaa
    14221 atccgggtta ttttgcgaag aaactatgag aaat
//
