LOCUS       c00063_gnlPro..        14826 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AODBDHJB_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:36:50
            Original ID  :: gnl|Prokka|AODBDHJB_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 154638
            Orig. end    :: 169464
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14826
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[164638:167609]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14826
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /kind="chemical_hybrid"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..14826
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     protocluster    743..14826
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[165380:169313]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10743..14675
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
     CDS             1594..2514
                     /locus_tag="ctg63_100"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
     CDS             2530..3888
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg63_101"
                     /sec_met_domain="MFS_1 (E-value: 4.9e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             4006..4140
                     /locus_tag="ctg63_102"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             4158..4412
                     /locus_tag="ctg63_103"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             4666..4977
                     /locus_tag="ctg63_104"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(5093..5509)
                     /locus_tag="ctg63_105"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRRKIGKTQPSFFNFPPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIEIQTFEDIRRKNILL"
     CDS             5526..5879
                     /locus_tag="ctg63_106"
                     /transl_table=11
                     /translation="MEKKRKIRTYGGYFEAFMETLTEKEQDKIQYGLLLLKTQERLSAK
                     FVKFIRDGVFELRTEYNNNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGHEIDKAVKIKE
                     EYYADKQSSNSRL"
     CDS             5845..6147
                     /locus_tag="ctg63_107"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(6217..8331)
                     /locus_tag="ctg63_108"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLMLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(8418..8648)
                     /locus_tag="ctg63_109"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             8842..9345
                     /locus_tag="ctg63_110"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             9405..9572
                     /locus_tag="ctg63_111"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             9559..10008
                     /locus_tag="ctg63_112"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_113"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10743..12971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_114"
                     /sec_met_domain="Gly_radical (E-value: 7.2e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13668..14675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: ACP_syn_III_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_115"
                     /sec_met_domain="Thiolase_N (E-value: 5.3e-11, bitscore:
                     35.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 2e-32, bitscore:
                     103.9, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 2e-34, bitscore:
                     110.6, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKINAVITGVGGYVPDYVLTNDEISKMVDTTDEWIMGRIGIKER
                     HILNEEGLGTSYMARKAAKQLMQRTKSRPDDIDLVIVATTTSDYRFPSTASILCERLGL
                     KNAFAFDMQAVCSGFLYAMETGANFIRSGKYKKIIIVGADKMSSVIDYTDRATCPIFGD
                     GAAAFMLEPTTEEVGIMDSVLRTDGKGLPFLHIKAGGSVCPPSYYSLDHHLHYIYQEGR
                     TVFKYAVANMSDSCEAIIARNHLTKEDIDWVIPHQANQRIITAVAQRLEVPSEKVMVNI
                     ERYGNTSAGTLPLCIWDFEKKLKKGDNLIFTAFGAGFAWGAVYVKWGYDPKEDA"
     CDS             complement(14726..14824)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_116"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1.2e-09,
                     bitscore: 31.1, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GACGLAPVVMIGEKVYGRLQPVDVKKIIEELE"
ORIGIN
        1 gttgaatgcc ggtggaaatg taatgtgggc ttggcaggta tttagctccg gcgatgataa
       61 gccgtcagaa aatatgaacg gttctccggc agtagatgag gctggtacta tttacggaac
      121 agctacgttt gcaggaatgg gaagtagcgc atttgctata ggaagtgatg gagtggagaa
      181 gtggcgtact cctttgggca atgtcggcac gctggatcaa ggcggtgttg tgataggact
      241 cgacggaagc attatcgtta cagtgaaacg tgctccgggg gaagcaaccg gaggaatcat
      301 ctctttgtct ccgggaggag ctatccaatg gcattacggc attgcggaag atgtaagcgg
      361 ttgtgcggca attgatcaag caggaaacat acatttcggc acccagtccg gcaattatta
      421 tatcattaaa ccggaagaat cggatgaaca attgattctg aaaaaagacc ttgctgcgtt
      481 gattagtgaa agtgactctc ctttaaaagg agattgggaa gcgggaatcg gtaaaatctg
      541 gagttcgcct accatcggac cggatggagc gatttatatc ggagtcacca atacggtgga
      601 ccctacaaag agcgtgttgg tagctttgga agatgaggga attaccgggg ccgcaacctc
      661 tgcctggccg atgaaaggga aggacagacg tcactccgga gcccaatcgg gagggaatgg
      721 agagaatccc ggtggagaag aaggaggaca gttgcctgtg acggggaatt tgaaagcaga
      781 tttaaagagt ctgtttgaaa gcacctctta taaagtgtgg ctctgcgcgc atcgtggaaa
      841 tacccaaaaa gggatgaaag aggggattcc cgaaaactcg ttacctgcga tagaacactc
      901 ggtcaaagca ggagttgaga tgatcgagct ggatgcacgg ccgacctctg acggtgtgtt
      961 ggtattgatg cacgacaaca ccatcgaccg gacaacaaac ggtagcggtg cggtgggaga
     1021 ctttacttat cagcaattac aacaatttta tctgaaagat gcatccggca atataactgg
     1081 cgaacgaatc ccgactttgg aggaagcgat gaagaaagga aaaggaaaag tttattataa
     1141 tctggatatt gtcaacaaga atgttgcggt aaatacgatc gtcgcattgc ttaaaaaatt
     1201 ggatatggaa ggttccactt tgctgtatgt atccaacaat cgcaattatg catttgattt
     1261 gaaggcagcc aacagtagtt tgctgttgca cccgatggcg aaagctaccg atgacatcac
     1321 atacttctcc tcatcctaca ctgataatgt acaaatgatg cagctgtcta cgtcagatgc
     1381 tatgggtgga acgatggtta atgagattaa agataaaggc tggcttcttt tctccaacat
     1441 tgtcggagcg aatgatacca atatgttgtc ggaaaactac tccggtttgg tgggaatgat
     1501 taacaaacgc atcaacattg tgcaaacaga ctatgctgaa gtagctgcca aatatttaaa
     1561 gtctaaagga tacagataat agtacatata gatatgaaga aatatataat gataggaatc
     1621 ttattcgcat ttcctttctg cctgtcggca gacgaaccgg tgaaagccat ttatgcgaag
     1681 ataacgaacc ctgacaataa agaaatcacg gttgtagctc atcgggcaga ctggcgttac
     1741 gcacccgaaa attcacttgc cgctattgaa agttccattc gtctgggagc tgacgtagtg
     1801 gagctggatg ttcagaaaac caaagacggt caattgatcc tgatgcatga caaaacgctg
     1861 gaccgaacga ctaccggaaa aggaaaggta gccgaatgga cattggattc tatccggaca
     1921 ctctatctga aaaatggagc ggcactcaaa accaagcatc gtgtacctac tttggaagag
     1981 gctttatggg ttgccaaagg tcgtgtgatg gtcaatctgg ataaagcata tccgatattt
     2041 gacgagattt ttcccatcct cgaaaagacg ggaacagtgg atcagattat catgaaaggt
     2101 tccaagcctg tggcagacgt aaagaaagac ttaggtaaat atctggaccg tatcatttat
     2161 atgcctatca ttcatttgga taagccggga gcaatgaagc aactggatga ttttatgacg
     2221 gagctgcatc ccgtagcttt tgaacttcta tttgtatcgg atacctgcca ggcccccaag
     2281 caagtaaaaa cgaagttgaa aggaaaaagt aaaatctggt ataatacgtt gtgggatacg
     2341 atggctggcg gacatgatga tgataaatcg ttggagaatc cggacgaagg atatggttat
     2401 ctgatcgata cactcggagc ggccatcatt cagacagacc gtactgccta tctgctggaa
     2461 tatttgcaat cgcgtaagaa gcgtagtgaa aacggccaag atgcgtatca ttaaaatata
     2521 gacttcttta tgggatttaa actattggat ttttataaaa tctctcctcc ggtgtccggg
     2581 ggagagactg atccggaacg ctctgtccgt ttcaagcgta ttcgttgggc tacctttctg
     2641 tctgccacta ccggatatgg catttattat gtttgtcgtt tgagtatgaa tgtaatccgt
     2701 aaaccgattg tagaagacgg agtttttacc gaaacccaac tggggattat cggttcctgc
     2761 ctttttttcg tatatgccgt cggtaagctg accaatggct ttcttgctga ccgtagcaat
     2821 gtaaagcgtt ttatgtctac cggattattg tgttctgctc tgatcaactt atgtctggga
     2881 ttcacgaatt ccttctttgc ttttgttctc ctttgggggt tgaatggttg gtttcagtcg
     2941 atgggggcag catcaggagt tgtgtcgctg actcgttggt atagtagtaa agagcgaggt
     3001 actttttatg gcttttggtc ggccagccac aatttgggtg aagctctgac ttttatatcc
     3061 atcgctttgc tggtcagttg gatgggatgg cgttatggga tgatcggtgc gggagtgatt
     3121 ggtttgcttg gttttctgat gatgcttgct tttatgcgtg atacgcctca aagtcagggc
     3181 tttttgctag atcggtgggg gacgtcagat gctcattccg tttccggtaa gcaaaccgag
     3241 gaattcaata aagctcagaa agcagttttg aagaatcctg ctatttggat tcttgcatta
     3301 tccagtgctt ttatgtatat cagccgttat gcagtcaata gctggggtgt tttctatctg
     3361 gaagcgcaaa aaggttattc tactttggat gctagtttta ttatatctat cagttctgta
     3421 tgcggaattg taggtacggt tttctcaggt attatttcag ataagttttt tgctggcagt
     3481 cgtaatgttc cggctttgat attcggatta atgaatgtgt ctgctctttg tttgtttcta
     3541 ttggttccgg gggtacattt ttgggtggat gctttggcga tggtgctctt cggtttgggc
     3601 attggagtgc tgatttgttt tttaggagga ctgatggctg tcgatattgc tcccagcaat
     3661 gcttcgggag ccgctttggg agttgtcggt atagcgagtt atataggagc cggtttgcag
     3721 gatgtgatga gtggcattct gatcgaaggt cagaagacgg tgcaaaatgg agtagaagtt
     3781 tacgatttta catatatcaa ttggttttgg attggtgcag ccttgctttc agtagtgttt
     3841 gctttgttgg tttggaatgc aggagagaaa agaagtgaaa taaattgagt acattaaagt
     3901 aaaaatagag tcattgtttt tgaaggtatt agtcaccatt tcgggaagca ggcaatagct
     3961 gtgctttccg gaatggcttt tttataatta ataaaaatcg tttttatgga aaattcattg
     4021 agtgatgaat tgttttgttc attgaagaat gaacttcgtg aagtagatgc acaaatcagt
     4081 gtgcatagta aaaaactgtt ggagctgatt gaccaaaaaa aagaattgtc gtccaactga
     4141 ttcgggaaga agaacaaatg acgcccactg ttatcgaata tcggggagat ccgaaacggt
     4201 atgtttctgt tattctaggt gccattgacc gggggaggtt gacgtataat ggagatgcga
     4261 attgcgaaca gacgttccgg tccttgtcaa gtgtgataga tgtcataagc cctaagaacg
     4321 ggaaagcgct cagtatcgaa acgttggtct cgtatgagaa gaaagaacgt gccggggagt
     4381 tttcagatta ttcggaaggg aaattcgaat aaaatgagta cctgagaggg aatttaagcc
     4441 cgttagcagt ataaatttga ctttaaaagt tgtatgatat tgaaactttt attatatttg
     4501 cacaatgaga agaaaagtaa tagcatacgg tcaatactac aaggattttc ttgccactct
     4561 gacagaaaag gaaattcaaa aagtgaaata tgtgctttca ttgcttggaa cagaaaaccc
     4621 catcatctga aatagataag gcattaaaaa taaaggagga atattatgag tacaaaaaac
     4681 aacatgctga ctgatatcag cgcagaactt gataaggagt tcggagcacc tgggactccg
     4741 gaacgtgaaa agttcgatga agaggcatac gctttttata ctggtcaaat actgttggat
     4801 gcacgacggg aagcaaaagt aactcagtct gaattagcaa agagaatcaa tgcaactaaa
     4861 tcgtatatct cacgtattga aagcggagct ataaatccaa gtgtaggaac attctaccga
     4921 attattaatg cattaggatt gaagattgaa atcgtaaaac caatcatggg tatatagtcg
     4981 aaaaaaccga aggatatctt aatccttcgg tttttcatat tttactttcc tatcacttcg
     5041 attaaccaac gatttaagtt ccggctttct gcactaaatt ccattccgat ctttacaata
     5101 agatattctt ccttcgtata tcttcaaagg tttgtatttc aataggaagt ttacgcatca
     5161 agttgtccat atctgattct tttgatcttt tgcacatcaa agataacaaa tatttcctga
     5221 agtctgcttc aattggtggg ctgatttgaa aatgcggtgg gaaattgaaa aaagacggtt
     5281 gtgtttttcc gattttccgc cgtctttttg gagaaagaaa aggtaaaaag tgagaggagt
     5341 gagagaggat ttctaacatt cgtatttttt ttagagaaat atagaaagta gaaataaaga
     5401 aataaaatag aaaaagtttc aattcctctc tcactcctct cacttttggg ggtgaagatg
     5461 atgaaaaata atataaaacg aggaaatgtg ttgtatagtt gaacaacatt ccttatattt
     5521 gcgttatgga aaagaaacgt aagatccgta catacggagg ttactttgag gctttcatgg
     5581 agactttaac cgaaaaggaa caagataaga ttcaatacgg attactcttg ttgaaaacac
     5641 aagaaagact ctccgctaaa tttgtgaagt ttattcggga tggagttttt gaacttcgca
     5701 cagaatataa taacaatata taccgggtat ttttcatatt tgatgatggt aatattgttg
     5761 tgttgttcaa tggctttcaa aagaagtcac aaaaaacacc tggtcatgaa attgataaag
     5821 cagttaaaat aaaggaggaa tattatgcag ataaacaatc atcaaatagt agattatgat
     5881 gctgtccttg atgccaaatt tggtgctgaa ggtactcccg aacgtgcaga ggcagaagaa
     5941 aaggcctacg ccttttatac aggacagatt atcgaggacg caagaaaaaa ggctaaaatc
     6001 actcaggctg aattagcccg gcgtatcggt tctgaccgtt cttatatttc aagagtagaa
     6061 agtggtcaga cagagcctaa agtatctact ttctatcgta taatgaatgc gttaggctgt
     6121 aaaatcgaat tttcaatgat tttgtaaaaa caataaatgc agagtatctg tcaagatgac
     6181 tctgcatttt gctatattca caaggctttc ccgcttctat tcatacagcc tgtttgattt
     6241 tacctgctcg atatctataa taaatacggc atatcggcgc ccgttatttc cttttttaga
     6301 ttcaaaatgg tgcttagtca tcaccttccc caactgtatt tttgatccga tggaatactg
     6361 ataaccggta cgctcacgta ttagttccgc aatctcactg acagtcagat aataaacctt
     6421 ctcgaaacgt tccggcttgc ggatatgcgt aagaaccatt tcttcttccg gtgaatgaaa
     6481 gatgaaagcc tcgttattct cttcaagccg ttcattgtcc gcttgcgtga accagtattg
     6541 atatcccggc ttattcagca gatatttgat ctgagcatag agctgcgcat aattgatggt
     6601 aataaattgg atggaataag gatgaaaaca aaggaaacgc cggttgcctg tcgtgtcgtg
     6661 aagcacttcc tgataattgc aggttcctgc aaaagaggcc gtatgaggga agttttgcga
     6721 acggcgtgca taaggcagac ggaaactgat cactttgcgc gttaccaaat ctttgaatgc
     6781 attcagttcc cggccgctca tcccttcaaa ctcgtcgaga ttgatcagca tagcctgcgt
     6841 tattttggct aaatcatctt tattgttcga attgattagt ccggtagaga gataagcacg
     6901 cagttcggga ggcaggagat tattgataaa ggtagtcttt cctatgttct gtatctcgct
     6961 gcatagcaga agtaccgtgt gattgacaat attctcctga gtagccgctg cgcacatcgc
     7021 caccagataa cgttccaggc attccgccca aaactcctga tgactcgtct ggacactatc
     7081 cgccaggata cggatatagt cggttccgtc ccattcgggc agtaattcaa aatactcgcg
     7141 aatgggatga tacgactggc tgaaatcgga gtaaatcaga ttttcgattg ttttgacagt
     7201 gcagggatat cccagttcgt tgatttctat ccagatactg ttttccatca tctcatccaa
     7261 gatgcggaaa ggctccggtt tctcggtgtc gggatgcctt ctgcgatatt ccatgatatg
     7321 cagcacttcg ttgtagcgtg tttcgtagtg ctcgctgata tattgctcta tccgtaatat
     7381 tcgtttctgc gtgccattca gtttacaggt attaaattcg tcggtatgag cgtaggcgct
     7441 attgatcaaa gaggctgtct cgtccgccgg aaagtctgta aactggcttt tgataaaggc
     7501 ggatgcttcc tcctgcggaa tgccgtagcg attgaaggta catgagagat ggtgcagata
     7561 attgttccgg tttcccgcta tgtatttttc ggacttgttg tgatagtagg ttaaagtcag
     7621 catcagagaa gcgttggcgg aatgggcgtt gagcgctgtg tcttcattcg tcggggggcc
     7681 gtccggagga gtctgttgtt tactgccgga gagattttta cgatttgaaa ccttgtagga
     7741 tgcctgaggt tgatctacaa gaaaagcgtc agcgttcgga ttgaaataaa tctccggatc
     7801 gtaagagaac agacaagtgc gtgctacatc ctggccggag gtgtcgattt ctatctgaca
     7861 gagttcggtg taaaaagaaa cgagtctggt gtaagctgca tgatggaagt cttctatttc
     7921 ctgaagggtt tcgggcaatg tctcatccgg atggcatgcg cgtactatga ttttcacgcc
     7981 catccctttg ggactgataa aggcgatgcg ggtgtaattg catctcttga tgatagggag
     8041 gatgcgtgcc aattcttctt tgctgaggtg gtcgatgtct atcacgatgt gtcccagata
     8101 tttgacgaga ttcactttgg tacgccttcc tcggtagctg gcggagaagg cgattgccgg
     8161 caattctttt ttcttctcat tggcagcctt ttctccttgc tctgcaaaga tgcggcgtat
     8221 ttcttcgact ttttcccggt aggtaaaact gccgatagtg gacactattt cttcttcggt
     8281 catttctgct attgcgtagt agaaaccttg aaatatggtg aaatgtttca tttttatttt
     8341 gattattgtt tgtcgatgca aaggaacttc tttgcggaaa tgtgtaaagg aactttgtat
     8401 aaaatggcaa taagttacta cggttcgccc aaaaagtgta tgatagttgc cacttgtttc
     8461 ggcgaaagga gacggttgcg tgcgcggtat ccttcctgtt cgagttcgtg caggagaggg
     8521 aggttgtaaa taatccaacg acgaagtatt tgtaaagcaa ctttgaggca gacatgggga
     8581 ttgtaaaggt gagccagttc cgctttggta taggtgcgga taaggaaaga atcttctttg
     8641 taattcatga tgttttcttc ttgttttatg ctataaagtt acataaaatt ccttgttatt
     8701 caaaggtttg acttcgtttt tattcgttgg gaatcaagaa acttcgttgg ggaatatggc
     8761 ttgtccggct atccttatct ttgtgctgtt aacaagaagg ggatgcatcc tatgtattat
     8821 aaactttaaa attattttat tatggcaatg acagtatctt attcagtggt gccgcgcaag
     8881 aatcctgcaa aaaagagcga accggcaaag tattatgcac aggcgcaggc gtcgggtgag
     8941 ctggactttg aagagttgtg cgaagcgatc accagtcgtt ctacttgtac ggaaacggat
     9001 gtacgtgcgg ctatttcggg tattctttac gaagtgaaac gtgcgttgaa ggcaggaaga
     9061 attgcgagac tgggcgattt gggcagtttg cagataggac tgaacagtga aggtgcggca
     9121 tcggtcaagg aattttccgg ttcaatgatt aagggggcgc atcttatttt ccgcccaggt
     9181 aagacgctgg cggagttgat gaagattctg agttatcagc aagtgcagac tcgtgcggtg
     9241 gcgcaggcgg gtgcaggcga tggcggggga gaagaccctg acaagaatcc ggattccggt
     9301 ggtgatggct ccggtgatga agaggctccg gaccctacgg tataattggc agacgggtca
     9361 aggtaataac gaattagaat aacttccatt aatattttga taagatgaaa gaaatagtaa
     9421 gtcggatttt agatgtgatc atgtatctga ttcctttctt cggaaagaga aagcgggaca
     9481 gggtggtgag agaagtgcgc tatcatacta cttgtaagga ggtgtgcaaa gtgaaaacga
     9541 cggaaaggga aaaggaacat gagaaagatt agtctgattg tgatccattg ttccgccacc
     9601 cgtgtcgatt gcgactttac ggcaaaggat gtggatacgg ctcaccgtta tcgtggcttt
     9661 tcgtgctggg ggtatcatta ttatatacgc aagtcgggcg agattgagcc gatgcgggat
     9721 gaagatacgg tcggagctca tgcacgtggc tataatgcga tcagcttagg tgtatgttat
     9781 gagggcggtc tggatgagaa tggaaaagct gcggatacgc gtaccccccg tcagaaggag
     9841 gcgctacatc gcttggtaca cgaattgttg cagcgttatc cggaagctaa agtagtaggg
     9901 catcgggatt taagtcccga caccaactat aatgggatcg tagatccttg ggaacggatt
     9961 aaagaatgcc cttgctttga ggtcattgga gaattctcca ttaattaact accaccgtag
    10021 tgaaatactc tttgaatacc tccgcagctt tttcaagctg ttcgggggta ttttctttta
    10081 cccctttcat cttgtattcc tgtcccatcg cttcgtactt atgtacgccc agtgtatggt
    10141 aaggcaatat ttccacccgt tggatcatct tgtattttcc gagtgcttct cccagtgcgc
    10201 gtatgtcttc ttcaaaatcg ctgtatccgg gcactagcac gtagcgtagc cagaaaggtt
    10261 tctcctgttc ttccagccag gcggccgtgc ggatggtttg ctcgttgctt cttccggtga
    10321 gcgtctgatg gcggttaggg ttgaattcct ttatatccaa taacacaaga tcggtcagtc
    10381 tgaataattc ttctacgtct tcgttccaaa gtcctccgtt gctgtccaga cagacatgga
    10441 tgcctttttc tttcagttcg cggaccagcg ggacgagtgc tttcgcctga aacgtcggtt
    10501 cgcctccgga gaaagtgatt cctcctcgtt tcccgaagaa ggggcgctgg ctcattgcca
    10561 tgcggacgat ttcttccggt ggggtaggcg tgcctccctt tcctgctatc gtatccggat
    10621 tggcgcaata gagacaacgg aagttgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcatcata tagagtaata
    10741 gattacatac gttcgtggaa gctacggctg ataacttcca gttggtgttc gcggctcagc
    10801 ttcacgaagt ttacggcata gccggaaacg cggatagtca gctgcggata gttctccgga
    10861 tgctccatgg catcgtacag catatcacgg ttcagtacgt ttacgttcag gtggtgggca
    10921 cctttggtga agtaaccgtc catcatcgtt acgaggttct cgatacggtc ttcgtccgta
    10981 gcacccagtg atttcggaac gatagagaag gtgttgctga taccgtcctg tgagtcacgg
    11041 taacgaagtt tcgctacaga actcagagaa gcgatcgcac cattcttgtc gcgtccgtgc
    11101 atcgggttgg cacccggagc gaaggcaaca cctttggcac gtccgtcggg agtagcaccg
    11161 gtctttttgc cgtacatcac attggaagtg atagtcagca aggagagggt aggacgggca
    11221 ttcttgtaaa caggcaattt cttcaattct tcgctgaaga agtataccag gtctacgccc
    11281 aggtggtcta ccttgtcgtt gtcgttaccg aagcaaggga attctccttc gatgtcgaaa
    11341 ccttctgtca gaccgatatc attgcggcgg gcagttactt tcgcatattt gatggcagac
    11401 agtgaatcga gggcgatgga aagtccggct acaccgtaag ctaggttgat gcgcgggttc
    11461 gtatctacaa gagccatctg ggccttctcg tagtaatact tgtcgtgcat atagtggatg
    11521 atgttcatcg cttcgttata tacgcgggcg atttcggtca gcactttttt gtagttgtcc
    11581 attacttctt cgaacttcag cgtgtcactg gtcagtacgg ggatgttctt caccatgact
    11641 gtaccggtat tctcgcaacg tccgccgttg atggcaagca acagggcttt ggccaggttg
    11701 caacgggcac cgaagaactg aatctgcttg cctatttcct ggtatgatac gcagcaggcg
    11761 attccgtagt cgtcggactg acgtacttcg cgcatcaggt cgtcattttc gtactggata
    11821 gaagaagtgt cgatagaaac ctttgcacag aattctttga atccttccgg aagttccggg
    11881 ctccagagta cggtcaggtt cggttccggt gaagggccga ggttgtacaa tgtctgcagg
    11941 aaacggaagg aggtctttgt cactttggta cgtccgtcgt tgagacgtcc gcccagagat
    12001 tcggttaccc aggtcgggtc gcctgcaaag atgtcattgt atgattgcat acgcaggtgg
    12061 cggaccatac gcagtttgat gacaaactgg tcgatcagct cttgcgcgaa tgattcggtg
    12121 atggttcctt tgctcagttc atattccaga tagatatcga ggaaagaaga aacgttaccc
    12181 agtgacatag cggcaccgtc ttgttctttg acggcggcaa ggtaagccat atatacccac
    12241 tgtacggctt cttgtgccgt gtaagcggga cggctcaggt cgagaccgta gtattcgccc
    12301 atcactttca tgtctttcag tgccttgatc tgttctgcca cttcttcgcg caggcggatg
    12361 cgggcctctg tcatcggacc ggtgaggttg tgcaaatctt ccttctttgc ttcgatcaga
    12421 cggtcgatgc cgtaaagagc catacggcgg tagtcaccga tgatgcgtcc gcgtgcataa
    12481 ttgtcgggaa gtccggtgag gaatcccagc gaacggaagg aacggatttc ttccgtatat
    12541 acgtcgaata ctccgtcgtt gtgcgtcttg cggtagtgag tgaaaatatc ttttacgcgg
    12601 tcgtccactt ccacgccgtt ttcgtgacag gctttgctga ctacgttgat acctccgaaa
    12661 ggcttgatgg cgcgtttcag aagttcgtct gtctgcaggc cgacgatcag ttcgttttcc
    12721 ttgtcgatat atccggcctt gtgggaagtg atggttgata cggtaacatt atctaatgag
    12781 cggacaccgt tgttttctct ttcttctgcc aacgcttcga ggcagcggtt ccatacggct
    12841 ttggtacgtt ctgtaggtcc ttcgaggaat gaagcatctc cgtaatacgg agtgatgtta
    12901 tgacttacga aatctctgac attgatttcg ctgctccaaa gaccgtcttt aaagatcttg
    12961 tttaattcca taaaatgata aaattagagg ttgtagttat cctattcttt agagcgcaca
    13021 aagttacaat catttttcat ataatcagca taaatatgct ctattttatg cttttcaaca
    13081 taaaatacct attaattgct atccttagga aaagattaga ttaaattttt agtgaaaact
    13141 cttgcaagtt taaaatatct tcgtaccttt gcaccgcttt taacgaaaag cacttctgat
    13201 aaggaagttt tggagaggtg gcagagtggt cgattgcggc ggtcttgaaa accgttgtac
    13261 cgcgaggtac ccggggttcg aatccctgtc tctccgctga aaagcagctt ttgggctgct
    13321 tttttgtttt tatggagggc gacgcctccg atgttgtgaa acgaaaacgg gagcgttttc
    13381 ttagtgttta ttgagttttt tgaaaggaga gatgctcgag tggttgaaga ggcacgcctg
    13441 gaaagcgtgt atacgccaaa agtgtatcgc gggttcgaat cccgctctct ccgctgaatc
    13501 tgaaatttag tcaaaacttc tcgttcttta gccaaaagtt cttttcatag gtcaaagtgt
    13561 ctggtatttc tagtactctt ctcttgtata tcattctctt ttctgtatat ttgcgcccga
    13621 tatttttttt gagatatcac atttttgtaa ttctgaaaat agacttgatg gataaaataa
    13681 atgcggtaat tactggggtc gggggatatg tgcccgatta tgtgctgact aatgatgaaa
    13741 tttctaaaat ggtggatacc accgacgaat ggatcatggg gcgtatcggc ataaaagaac
    13801 gacatatctt gaatgaagag gggcttggaa cttcgtatat ggcccgtaag gccgccaagc
    13861 agttgatgca acgcacaaag agtcgtcccg atgatatcga tctggtcatt gtcgccacta
    13921 ctacttcgga ttatcgtttt ccttcaacgg catctatctt gtgcgaaagg ctggggctga
    13981 agaatgcttt cgctttcgat atgcaggcgg tttgcagcgg tttcctgtat gcgatggaaa
    14041 cgggagcgaa ttttatccgt tcggggaaat ataaaaagat tattattgta ggtgctgata
    14101 agatgtcatc cgtaatcgat tatacggacc gtgccacttg ccctatcttt ggcgacggtg
    14161 cggccgcttt tatgctggaa ccgactacgg aagaggtcgg catcatggat tcggtgttga
    14221 gaacggatgg taaagggctg ccttttctgc atataaaagc gggaggttcc gtatgtcctc
    14281 cttcctatta ttcattggat catcatctgc attatattta tcaggaaggc cgcacggtgt
    14341 tcaagtatgc cgtagcgaat atgtcggatt cctgtgaagc tattatcgcc agaaaccact
    14401 tgactaagga ggatattgat tgggtgattc cccaccaggc taaccagcgt atcattaccg
    14461 ctgtggcgca acggttggaa gtaccgtccg agaaagtgat ggtcaacatc gaacgttatg
    14521 gcaataccag tgccggcacg cttccgcttt gcatttggga ttttgagaag aaattgaaga
    14581 aaggcgataa tctgatattt accgcattcg gtgcaggatt tgcctgggga gcggtttatg
    14641 tgaagtgggg atatgacccc aaagaagatg cgtgacatat cgggtacccg atacgtcaca
    14701 tcctcttttg aagggtagga gagacttatt ccagttcctc gataatcttc ttcacatcta
    14761 ccggttgcag tcgtccgtac accttttcgc cgatcatcac taccggagcc agtccacagg
    14821 cgccta
//
