LOCUS       gnlProkkaPLOPOAKI_137  12506 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PLOPOAKI_137.
ACCESSION   gnlProkkaPLOPOAKI_137
VERSION     gnlProkkaPLOPOAKI_137
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:21:10
            Original ID  :: gnl|Prokka|PLOPOAKI_137
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 13512
            Orig. end    :: 26018
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12506
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12506
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12506
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(205..1017)
                     /locus_tag="ctg137_10"
                     /transl_table=11
                     /translation="MISITRDKRMLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTP
                     YSGDEAEKVRRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHG
                     VDALITREPGYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEF
                     GTSGEDVVACIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANR
                     MQILAFGVPSGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(1014..2105)
                     /locus_tag="ctg137_11"
                     /transl_table=11
                     /translation="MRREKYCPNGGPDGGDGGRGGHIILRGNRNYWTLLHLKYDRHAMA
                     GHGESGSKNRSFGKDGADKVIEVPCGTVVYNAETGEYLCDVTDDGQEVILLKGGRGGQG
                     NSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLADVGLVGFPNAGKSTLLSAISAAKPK
                     IADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIEGASQGKGLGLRFLRHIERNSLLLFM
                     VPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLAITKSDMLDQELMDEIEPTLPEGVPH
                     IFISSVSGLGISVLKDILWEELNKESNKIEDIVHRPKDVTRLQQELKDMGEDEELDYEY
                     EEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(2270..2839)
                     /locus_tag="ctg137_12"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(2899..3435)
                     /locus_tag="ctg137_13"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3476..5020)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg137_14"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             5926..6543
                     /locus_tag="ctg137_15"
                     /transl_table=11
                     /translation="MTNENEKVVQVNYHNGSLTLKAKEIGRASIKIEDSSNNMYILSVV
                     VKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDL
                     YYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFL
                     PLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             7053..8564
                     /locus_tag="ctg137_16"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8638..9702
                     /locus_tag="ctg137_17"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9724..10011
                     /locus_tag="ctg137_18"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_19"
                     /sec_met_domain="PF05402 (E-value: 7.6e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 3.2e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10393..11781)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg137_20"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             12412..12504
                     /locus_tag="ctg137_21"
                     /transl_table=11
                     /translation="MKHISKAAITIKIMNNKYIFSYFELALIINF"
ORIGIN
        1 aatgtctgcc atttgggtgg tggtagtcaa gtcttctgtg aaagtattta tttctttcca
       61 aagtccatcg cagtaagcag tattcttcac tgctgcatat acggctgctc cggcaaaaac
      121 agggcaggcg ttctttattt cctgagatac ttttatttca aacatacttt tattcaagtt
      181 tatatcaact tacgttcaag tctattattt atgaatcatg atccccgaca gaatccgtcc
      241 ggacttaatg cccaaacgcc ttgccgagaa aaactcgtcg tgatgaatat acgtacatat
      301 ccgggcaagc tccacttgtc cggacggcac accgaaagca aggatttgca tccggttcgc
      361 ttcccacaag tcgatatgat gttttccggt ttcctctttc ctgatagaaa tacgaggcat
      421 atcaaaacca ttcttctgaa atgcttcata cacttcctca cccacttcaa aagaagccaa
      481 tgagatactc ggaccgatac aggcaactac atcttctcca cttgtgccaa actccttttc
      541 catccgcaac aaagtatcac gcacgatgta tgctaccgtc cctctccatc cggcatgaat
      601 ggcagctatg gcactatgtt tcttatcata tatcaacaca ggaacacaat ccgcagtaga
      661 aatacaaaga caatatcccg gctcgcgggt aatcaaagca tccactccgt gcagcatctc
      721 ctgtcgttgt tgagacgaag ccgataaata agcatccccg atcagcaggc aattcgtctc
      781 atgagtctgc acaggaatca ccagttcttc gggtgtctgc gacattcctt ccatcagaag
      841 cgtttgattc cgccggacct tttccgcctc gtctccactg tagggcgtac agttgaatga
      901 cgcataattt ccttcgctgc accctccctg ccgggtagtt acaaaatgag aaatgttgga
      961 gtatgagctt aacgactcat accccaacat tcttttatct cttgtgattg aaatcatttt
     1021 tcttcccaat cctcttcttc gtattcgtag tcgagatcat catcgtcgtc gtcagcgtct
     1081 tcctcatatt catagtcgag ttcttcatcc tcgcccatgt ccttgagttc ctgctgcaga
     1141 cgggtcacgt ctttcggacg gtgaacaatg tcttctatct tattactttc cttgttcagt
     1201 tcctcccaca gaatgtcttt caacactgag attcccaaac cggaaacaga agaaatgaat
     1261 atatgcggaa caccctcggg caatgtcggt tcaatctcgt ccatcagctc ctgatcgagc
     1321 atatcgctct tcgtgatagc cagcacacgt tgtttgtcca gcatttcggg attgaacgta
     1381 cgcagctcat tcagcaatac ttcatactcc ttgcggatat catcgctatc tgccggaacc
     1441 atgaacaaca gcaacgagtt acgctcgata tgacgcagaa accgcagtcc caatcctttt
     1501 ccctgactgg ctccctcgat gatgcccggt atgtccgcca tcacgaatga ctttccatcg
     1561 cgataggaaa caattcccag attcggttcg agtgtcgtaa acgggtaatc ggcaatcttc
     1621 ggtttcgcag ccgaaatggc agaaagcaac gtagactttc ccgcattcgg gaaacctacc
     1681 agtcctacat ctgccaacag tttcagctcc atgatcaccg tcatttcctg catcggttcg
     1741 cccggctgcg caaagcgcgg agcctgacgg gtagccgtct tgaaatgact gttgccctga
     1801 ccgccacgac cgcctttcag caagatcact tcctgtccgt cgtccgtcac atcgcaaagg
     1861 tattctccgg tttcggcgtt atacactacc gttccgcagg gtacttcgat cactttatcc
     1921 gcaccgtctt ttccgaaact acggttcttg ctgcccgatt cgccatgacc tgccatcgca
     1981 tgacggtcat acttcaagtg aagcaatgtc cagtaattac ggttaccgcg caagataata
     2041 tggcctcctc ttccaccatc gcccccatcg ggacctccgt taggacaata tttctcgcgc
     2101 ctcatgtgcg tagagcctct tccgcccttg cccgagcgac agtatatctt tacgtaatca
     2161 acaaaattcg attcagccat atttttttaa agagttaaag tagtcagtag ttagagcagt
     2221 taattagaac actccggcta ctgacttatt tatttataat attgtattat tacaatttat
     2281 ctactgcttc gcagatttca gcgaagatac cttccatagt acccaagccg ttgatgtgtt
     2341 ggtatttctt ttcgttcttg taccagtcga tcagtggagc agtctgtgaa tgatatacat
     2401 gcagacgttt cttgattgtt tcttcgttat catcagcacg accggaatcc ttgccacgtt
     2461 taatgagacg taccatcagt tcttcttccg gaacatccag atcaaccatt acagaaacgt
     2521 cctgtcctct ttctgccaac attttcttta atgcttctgc ctgtgcaatt gttcttggga
     2581 aaccgtcgaa aattacacct ttgctatctt tgaagctgtc gaatacgctt gccagaatat
     2641 caatcattaa ttcatcagga atcaattgac cttggtcgat gtaaccttta gctgttttac
     2701 ccagttctgt gccattcttg atttcagcac gcaatacatc tcctgtcgag atgtgattga
     2761 ttccatactt ttctacgata cgttcgctct gtgttccttt tcctgaaccc ggagcaccga
     2821 aaattacgat gttcaacatt ttgttattta caatttaacg atttactatt taccatttaa
     2881 actggtacct atttaatatt aatctactac tgtataaata tcgggataat tacgtccgaa
     2941 accatcataa tccagtccgt aacctacgat aaagtcgttc gggatttcca tcgctacata
     3001 ttcaatgttg aggtttacct tgagcttttc aggtttcacc aacagagaag cgatatgaat
     3061 agcttcggga ttgcgtgtac ctaatgtttc gagcagtcgc tgcatcgtca gtcctgtgtc
     3121 tacgatatct tctacgatca caatggtacg tccggcaatg tcttcattca ggccgattac
     3181 ctctttaatc actccggtgg aagtgatgcc ctgataagaa gccaacttca caaatgagat
     3241 ttcacaaggg atggtgatgt gcttcagtaa atcagcggta aacatgaacg aaccgttcaa
     3301 cacactaagg aaaagcggat tcttacctgc taaatcgcgg ttaatttcgt tcgctacgcg
     3361 aatcacttct ttctgaattt cttgttcctt aatagaaacg gtaaacaatt tgtcttttat
     3421 ctgaatggta tccataaccg gtaatttaaa aataaccttg caaaaatacg attttttatt
     3481 ctaccccgtg catcatcttc tgtaatttct tcgagagaag gaacagaatc agtgaggcaa
     3541 caccggacat aatgacgaac agcatgaaga agtcgtacat ggtagcgatc tgataaccaa
     3601 ggattgattt cacttttccg tcttcgggat agaggccgct cagcatacct gcaaatttat
     3661 ttgcggtggc ggtagaaaga taccagatcc ccatcatcaa ggaggcgaaa cgtaacggac
     3721 tcaacttatt aaccatagaa agcccgatag gtgacagagc gatttctccc attgtatgaa
     3781 taaagtaaag ccctgtcagc cagatcatgc tcacctttac tcctggaata gcatctttca
     3841 ctccaaaaca gatgaagaga taaccaagag aaagcagcaa cagaccgatt gcctgtttgg
     3901 taggggaagc cggttccatg tttcgcttat tcagaaagct ccatataccg ggcataatat
     3961 aggcaaggat cactacaaaa agcggattga atgactggaa ccacgaagcc ggcatctccc
     4021 agccgaaaat gctgcggtca gtctgttcgg aagcgaataa tgtcagagaa gctcctgcct
     4081 gctcgtaagc tgcccagaag aaaatgacga agaaagctac gatatagatt acgaaaatac
     4141 ggctacgttc tactttggtc aatgaaccat ccagcagaat gagcactgga aagacaatac
     4201 aagccgtaaa gatacccaca ctaatccagt catcgctaaa ggcatagcta aaaaaggcta
     4261 ttaaggcaac tgtaagggca gtaatgatga tgatattacg tactttggta cgtttgtcca
     4321 tcttcggatg tgaaatatgt tcggctttat cctccttttt ttcacgtctg gcgtcgggga
     4381 cgataccaat cggttcaccg gaaggagaga aaaggtattt attcttctga gtttcaaaga
     4441 ggacaacagt gaacagcgtc atgattccgg atgcgaggaa tccccattta aagtcctgcg
     4501 gattccctgt gtctcccaag aaaccgcaaa tcaaaggagc agcgaaagaa cctacattaa
     4561 cacccatata gaaaatggtg tatgcagcat ccaaccgttt gtccccgggt tcatataatt
     4621 gcccgacgag cgaagaaacg gtaggcttaa agcaaccgtt acctaaaatc atgaatccga
     4681 gtccgccata catcagccag tgggcaaggt ctgtattgtt cagtgaagag gcactcataa
     4741 acatcaggaa ctgaccgact gccatcatca ccgctcccca aaataccgaa cgacggatgc
     4801 cccaatattt atcggcaatg tatccgccga tcaacggagt cagatagacc agtccggtgt
     4861 agctaccgta gatagaggcc gccgcttctt tatcaaaaag caatgcctgc gtcagaaaga
     4921 ggataaagat agcacgcata ccgtagtaac tgaaacgttc tgccgtgctc gttgcgaaaa
     4981 ttaggtaaag gcctttcggg tgccctttca atgaactcat gaattatgtg tttagtagtt
     5041 tatggggtgc aaaggtacta aaaagtagat taaatgcctc aaaaaagaag attcttatgg
     5101 aatagaaaaa tacaggatgg cgtgcaaaaa gtctcagtta cccaccttat tatgttttca
     5161 acagtgtaaa taatcaagtg gatattctcc ttaaatgtgg gtcagtcccc atttatccaa
     5221 aggtaaattc aacattctca atactggcat agagcattcc ttcttttttt ctaagcagga
     5281 ttttgttttc ccttgccaac cagccgatag caatcgctac atcctcgaac gtcaaaccta
     5341 actcatggca caaagtgaac atggacagtt cgcccttttc atttaagatg cgccatactt
     5401 tcccggcatt tgagccaatt cttttctttt ccatcatgca aactttagaa gattaaacaa
     5461 tttatattta taatctaaac attgtgagca caggagaata acgtaaagca cattactgca
     5521 ctacaaagat atcatttttt tcgaaaaaag caaataatca aggcattagc tgctattatt
     5581 agttacattc cgaccattta ttccgatctc tgctaaaaaa tagcacaaat aaagaaacag
     5641 ttcaattctt tttcataagt ttgcagacga gaactaaact aatatcacac atttaaaact
     5701 ttaactagca tgactaccaa aaaacttgca ggaatacttt cgttattcct ttgtattatt
     5761 tgcctcgtga gctgtaatga caatgatgac aacttttctc caatcactct ggaatatgaa
     5821 gatcctcaaa ttaagttcga caacgagagc cgttcttaca cactgactcc gttcagcaaa
     5881 gaaacgacac cactcttcat caagggtgga gacggaactt acaaagtgac caatgagaat
     5941 gagaaagtgg tacaagtaaa ctaccacaac ggaagtttaa cattgaaggc aaaggaaata
     6001 ggacgcgcat ccatcaagat agaagacagt tcgaataata tgtatatact gtctgtcgtt
     6061 gtaaaatatc gtactcttac tcataaggcg tttacagcaa aagtcattgt gaagggagac
     6121 gagcttacat ctgaagaaca cactgagtta atgaacaaag tgggcaattc atatccgatt
     6181 aataaatatg tatttacttt tatgaatgcg gaagacagca aaggaacagt agatttgtat
     6241 tattcagata ataacatgaa aacaggcaac tttgaaaaag aacatatagt gctggatgaa
     6301 gaaaatgcca ttcccatcaa aggtgaatac aaattgagtg agtattaccg tataacaatc
     6361 aaagaagata atggcaaagt tattgatact ttctatatta ccaagaactt tctaccactc
     6421 ctcaatacaa gaatgaatgc tcatccgtta attcagtact gttttgtcag agatttaacc
     6481 gcacagtaca aacaagatta ccttgcactg gaaaatgcat atctgattca aatagcagaa
     6541 tgagaactac actgattttc ttctttagca gagtgaatag agtatttatt atatgagcaa
     6601 actccccatt agatttagca aaaaacaata agctattagc taatcaagaa tatgcccata
     6661 gcatatttat cacaatcacc tcttccaccc ttttcctgaa cctttgatga ataaggcgat
     6721 tgcgggtgaa agaggtgaac cggaggaata tacagtagta gaaacacgca tgggaaggtt
     6781 aacaaacagc catgaatgtt ctccggagag agtaaaggta aatgagacaa caatgcttgt
     6841 tatactgcgt tacaagcatt gatatctacc ataacaatca ttaatatctg acttctcaac
     6901 tattaataac tgacacatca actattaata cctgacaact caagtattaa tacctgaagt
     6961 tccttcccaa aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggaac
     7141 gtgccgcaca ggcgctgact aaagccatca ctaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgccagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg actgatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcactgatc aaaccacgcc aacaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcgcgtg
     7861 cctgtctgcg ctcgggagta ggtctgctga ccgtacacgc gccgttatgc aacaacgata
     7921 ttctgcaaac gtccgccccc gaagccatgg tagaaacaga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca
     8041 acgaggaaac ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac
     8101 tggatgccga cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtgacctg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaacg tcccctacag cagcaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
     9361 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
     9481 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgcttat cattatgggc
     9961 gtactgatag gatgcgctgt ccttctatgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatgctg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctggccgt
    10141 ctatcaggtt ccatacggcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggg atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
    10381 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
    10441 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
    10501 catcggcaag gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
    10561 gttcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
    10621 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
    10681 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
    10741 ccaccatata ttcagaatag gaagagcgaa catcgtgtgt acgaaaatca gcatcaccga
    10801 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tacaatgaac cgaacaacgg
    10861 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
    10921 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
    10981 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttggtaa tgatatagac
    11041 aatgtctttc atgcggaaag gttcttccgg ttccagtcct tccgcatcca gtgaagcatc
    11101 cagtttctta tcgtagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
    11161 gagacagaac agaataggag cgggaatatt ggtatggaat acgccgctct catccgtaga
    11221 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagtcgttc caatacgcgc
    11281 ggtcgccatt tccagtccca tagcgagagc catctctttg cctttaaacc acttcacgat
    11341 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccgaaaatag cataacccaa
    11401 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
    11461 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
    11521 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
    11581 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
    11641 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
    11701 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgcggagt cattcagctt
    11761 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
    11821 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
    11881 gacatctgac cggatattcc tatatgaaga agagcagacc gggcccaata ataaagacag
    11941 acgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
    12001 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
    12061 ctgtcactga attattctgc tgcaggagca ggagtttcag tagccggagc ttccgttgct
    12121 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
    12181 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagctgca
    12241 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
    12301 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
    12361 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
    12421 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
    12481 gaattagcgt taataatcaa tttctc
//
