LOCUS       c00007_gnlPro..        13267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GMHEGFNF_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 17:46:35
            Original ID  :: gnl|Prokka|GMHEGFNF_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 49088
            Orig. end    :: 62355
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[59088:62047]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12959
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             501..1610
                     /locus_tag="ctg7_41"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
     CDS             1633..2646
                     /locus_tag="ctg7_42"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEVET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             2896..4164
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_43"
                     /sec_met_domain="MFS_1 (E-value: 3.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             4219..5217
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_44"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.2e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(5321..5794)
                     /locus_tag="ctg7_45"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             5863..6861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_46"
                     /sec_met_domain="LysR_substrate (E-value: 9.3e-47,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.9e-18, bitscore: 55.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTTIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             complement(6966..7718)
                     /locus_tag="ctg7_47"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             7906..8454
                     /locus_tag="ctg7_48"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8506..9768
                     /locus_tag="ctg7_49"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATTPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_50"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(10731..12959)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_51"
                     /sec_met_domain="Gly_radical (E-value: 1.4e-46, bitscore:
                     149.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1165.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYITVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLRDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13049..13162
                     /locus_tag="ctg7_52"
                     /transl_table=11
                     /translation="MLNSIKIPIYGEKLDSSYYFQIYFSNIFLRNNLQVKK"
ORIGIN
        1 gaaagaatcg gacctaaatc gggtacggga cggttacttg tgattgatgg cgagcctcaa
       61 agtattcatc cggaaaccgg gccttacttt gactatttca ttgtgcaggc atactctaac
      121 cttgcgggta attccgacgc taatcttgac agacgtctgg ctggtacgat tgccaacttt
      181 aaaggaatac ttcctccgga gaaagtggct aatatgtaca tcgttacgga gaatttcgaa
      241 tcttatgctc cggcaggagg aggtgattat gtagatcgtt acggaaacaa aatgagagca
      301 cttgccggca tggcacgctg gactccgact attgacggaa aacaggtacg gaagggtgga
      361 gtaggcacct atcacatgga atatgactat ccgggcgaca tcgaatataa gtacctgcgt
      421 gaagcaatca gaataatgaa tcctgctgta aaatgacttt aaagaatttg attatgaaaa
      481 gaataacaat aaaacaatgt ttgcttgcct gtttcgttct gccgatgatc ctggcaggat
      541 gcaacgatgc cgattaccag gttatcgaca atgcgattta tttgaatgaa gcatccgaga
      601 atggttcggc aaaggttacc gttgatcctg aaaatgtaac aacaactact ctgaccgtac
      661 gtgtgggaca gcctgtaacc gaaaatgtga ctgctgtcct gacggtagat ccttctattc
      721 ttaaagagta caatgaagct aatgaaactt cgtacgaagt ccttcccgag cagtatttta
      781 cttatgacaa agagataaag atagcggcag gcgatgttag cgcaatcccc agtgagttta
      841 gagtgaaacc ttattcaaac gaaaacggag aattgtatgc tattccggta tctctcacag
      901 aaattcaggg gccggtgtcc acaatcgggc tttcgtcgaa gtttatcatt ttgctggata
      961 agccgctgat acagtctgta ccgtttatga atacgaccaa tgccgtgaag cccgccaagg
     1021 acgaattgtg gggagtgaca accaatgaat ggtcactcga ggcttgggta cagatggacg
     1081 gattcgatat taataatcag gctatattta attcgggcag cagcgaccac gaggtttata
     1141 tccgtttcgg tgacgctatg atcccttata attcattaca ggtgaagaca cttggaagtc
     1201 aggtcaatac ggtgactttg tttgagaaga ataagtggta tcatctggcc ttcgtttata
     1261 attcttccgg gttattgtcg atttatatca acggagtgct cgacgtgact ctgcagacaa
     1321 agggtggccc ggttagattc gacaagatga acatggtttc gagcggtagt tacttccgca
     1381 acaattgtca gatggcccag gtgcgtcttt ggaagagcgc aatcagccag acgcaaattc
     1441 agtccaacat gtattttgcc gtgaagcccg ccgatccgaa cctgataggc tattggaaaa
     1501 tggatgaagg taagggaaat gcctttgtcg actgtaccgg acacggatac gatttggtgg
     1561 caggaggaac tcttgtctgg aaagagcatg ttcgttttga taagcaataa ctatgtaaaa
     1621 agaagataag atatgaatag acatttgaat tttgtgacct taatctgcct gataacaggc
     1681 tttgtatcgt tggcttcgtg cagcaacgat gatgatgaaa tggacaaata tcaaaagata
     1741 tatatcagaa cgggagttgc accgggggcc gaaatgggtg ctgcggtagt ggtggattgt
     1801 gtgagcaatt cctctactgc cgaccgttct gattttgaaa tacaattgtg tgccgtacag
     1861 ccggttacgc gggatgtcac tgccgctttg ggagtagata cgctgaaagt ggatacttac
     1921 aattctgcca ataagacgaa atgtaagttg ttgccccaag ataattatac cattgaaaca
     1981 agtgaagttg tcttaaaaac gggacagaca gtggccgatt catcttttca ggtcgttttg
     2041 aagaatatag aaaagttgac taatcctgac ggatatgtgc ttcccgtggc gcttaaagga
     2101 gttacgggca tggacgaaca ggctgtcagt acatctatga agacggttta tatccggatt
     2161 tataccagcg tgctttatac cagttatacg aaacccggga attggtccgc tgtagatcga
     2221 agtgcgtgga gtgtaagttg cagcaatgtt tatgccgatg atgatgccaa atatggtgca
     2281 catctggcta ttgacggtga gataaatact acttggttta catggggagt ggctaatgcc
     2341 ggagagtgtt ggtggaatac ggtactggac cggcctgtta ccttaaccgg attttcggtc
     2401 actaaacaga gtgcctacgg atcgggttat aatctgagaa gtgctgagat taaggttcgg
     2461 aaagaggttg aaaccgagtg ggttacttac ccgagagtct tgactttcag aaattttaaa
     2521 ggggctgatc cgcaatatgc ggccatcgaa ccacctatcc cgaatgtaaa ggaattcaga
     2581 ataaactgtc tgactccgga taattatacc gggtttgctg agataaattt atatgtgaag
     2641 caatagaggt gtttagattg tagataaggg ggcgagaggc atcggggatg aaagtcttcg
     2701 gtgcttcttt gcgtgtgtcg tattgataaa gtttaataaa aaaagggtga tagaggttag
     2761 tagttttccc gggtgagttg tattattaaa taatgaaagc aacttcttgt cgtaatcttg
     2821 ggttatgttt ttaatatccc ctatctttgc ttactggaat tgttaaccga tggaattatt
     2881 ataaaaaact aactgatgaa taaaaagccg ataagccctg tatgttgggt gcctactgtt
     2941 tactttgcta tgggattgcc gtttgtggcc ctttcgatgg tttctgtcct tatgttttcc
     3001 gatatggaag tgtcgaatgc acagattgct ttctggactt ctcttattat gcttccctgg
     3061 acattgaagc ctttatggag tccgtttctg gaaatgttta aaacgaaaaa gtactttgtt
     3121 gtcgctacgg aaatcattac cggactggca tttgcattgg tagcactttc gctgccgctg
     3181 cccgactttt ttcgttatgc catcgctctg atggggatca ttgctctcag tggtgcgact
     3241 catgacattg cgggtgacgg agtatacctg actgaactga ctgctaccca gcaagccaag
     3301 tatatcggtt ggcagggagc tttttataat ctggccaaga tacttgccaa cggaggcttg
     3361 gtttggttgg caggtatgct gaaggatgaa tttggagtgg tacatgcctg gatgattgtc
     3421 atgttgatgt gtgcgggtat tatgattctg atcggtcttt accacatccg gattttgcct
     3481 tcgggaggag gcgcttccgg tgaagtgaat acgatgagtg acgcattgaa tatgctttgg
     3541 gaagtcatcc gctctttttt ccaaaaaaaa catattgctt tctacattgt ctttatcatt
     3601 ttgtaccggt ttgccgaagg atatgccatc aagattgtac cgttgttcct gaaagcgtcg
     3661 gttgcggatg gtggattggg actcagcact caggatatcg gactggtata tggtacgttc
     3721 ggagcgggag cttttattct cggttcgctt ttggccggtt attacatttc ggctttcgga
     3781 cttcggaaga ctttgttttc tttatgttgc gcttttaata ttccgttctt ggtatatttc
     3841 ctgttagccc tttaccagcc ttccgatcta tggattattg gtatggccat tgtgtctgaa
     3901 tacttgggtt acgggtttgg ttttgtcgga ttgatgctct ttatgatgca gcaagtggct
     3961 cccggcaaac atcagatggc acattatgct tttgctaccg gtattatgaa tctgggggtg
     4021 atgcttcccg gaatgatgag cggatacctg agcgattggc tgggttatcg cgatttcttt
     4081 atctgggtac ttatcgctac cataccggct tttatcgtga cttggctggt acctttcaca
     4141 tatccggacg gaaagaagaa ataaaaagag attttcaata taaacaagat atatacataa
     4201 tattaattta atcgaatcat ggaagaaatt aaaattgcag gtgctgcttt gccggctatg
     4261 ccttgggaag aacgtccggc aggatgtaaa gatgtagtgt ggcgttgttc ggccaatccg
     4321 attattccgc gcgacttgct ccctacttca aacagtatat tcaacagtgc cgtagttccg
     4381 tttaaggatg gctatgcagg ggtgttccgt tgtgatgata ctaatcgtcg catgcgtttg
     4441 catgtgggat tcagcaagga tgctgttcat tgggatatca acgaagaacc gttaaagttt
     4501 caatgtgatg atgctgaggt tggaacctgg gtctatggat atgacccacg ggtttgcttt
     4561 atcgaagacc gctactatgt gacctggtgt aatggctatc atggtcctac tatcggtgtg
     4621 gcctacacct atgattttgt tacttttcac cagttggaga atgcctttat tcctttcaat
     4681 cggaatggag tcttgttccc tcgtaagata aacggtcgtt ttgcgatgtt gagccgcccg
     4741 agtgataatg ggcatactcc ttttggagat attttctata gcgagtctcc cgatatggag
     4801 ttttggggac gtcatcgtca tgttatgtcg ccggctccgt tcgaagacag tgcctggcag
     4861 tgtaccaaga tcggtgcagg gcctatcccg attgaaacct cggaaggctg gttgctgatc
     4921 tatcatggtg tattggcttc ctgcaacggt tttgtgtata gttttggttc ggcactgctt
     4981 gacatcgatc aaccctggaa agtaaaattc cgttcggggc cttatctgat ttcacctcag
     5041 aaggattacg aatgtatggg tgatgtgcct aatgtctgtt tcccatgcgc ggcgcttcat
     5101 gattcggaga ccggacggat tgccatctat tatgggtgtg cggatacagt gaccgggctc
     5161 gcattcggat acattccgga gattattgaa tttaccaaac gtacaagtat catctgaatc
     5221 gaataaaaca gaaagggtgt agctatcccg ccgggatggc tacacccttt tgcttgtatg
     5281 gctacacctt ttcggtcaga tggctacacc ctttcggctg ttatccgttg tatgcagtca
     5341 gcatccaaac catcttttcc tgttctttca ggtagtcgct catcatggcc actgttactt
     5401 cgtcgttgtg tgaagaggcg agagacagga ttttacgttc ttccgcaatc agatgcccgt
     5461 aagtttcgag aatatgattc agagcgtcgt cggccttatt cactccgtcc acttccttga
     5521 tctgcgccat cttcagatag tcactgtatt tattggcggg agttcctccc agcatcagta
     5581 tacgttcggc tatttcgtcc accttttcgg cggctccatt atataaatct tcaaacttgc
     5641 tgtgcagtac gaagaaaccg tgtcctttga tgttccagtg aaatcctctc aggtttgcat
     5701 aatgaatctg aaaatcggca agcagttgct gtaatgacag tacgatggtg ttagctcctt
     5761 tttcttccaa atgtgtataa tttaaagtct tcataatgat attgtttttt tgagttaata
     5821 ctatatttct tctttttatc tggaacaaag atacggcaca aaatgattcg tgtcaaactg
     5881 aaaatttcta tctttgcatt gatagattct atatctttaa taaatcagag aacgatgact
     5941 atacaacaat tggaatatat tctggctgta gaccagttcc ggcattttgc taaagctgcc
     6001 gagtattgcc gggtgacgca acctactttg agtgcaatga tccaaaagct ggaagacgaa
     6061 ttgggggtga aactgttcga ccgtagcatg acaccggttt gccctactac cattggtaag
     6121 aaagtgctgg aacaggcccg taagattctt tcggaagtta tctgtgtcaa ggagatcatc
     6181 agcgaagaac agcactccct gtcgggtaca ttccgattgg cagtgttacc gacgattgca
     6241 ccttatcttc tgccccgttt ctttccgcaa ctgatggaga aatacccgga tcttgatata
     6301 cgggtgatgg agatgaagac gcccgacatt cgcaaggctc tgctgaccgg tgaagcggat
     6361 gctgctatca ttgccagcat gctggatgat gccgcattaa cggaagagac cttattctac
     6421 gagcaattcc tgggctatgt ctcaaagaag gaaccgttgt tcaagcacga tgtgattcgt
     6481 acgtccgatg tgacagggga acggctttgg cttcttgacg aagggcattg cttccgcgat
     6541 cagttggttc gtttttgtca gatggaagcg gttaagatca gccaaatggc gtatcggctg
     6601 ggtagtatgg aaacctttat gcatatggtg gagagtggta aggggattac gtttattccc
     6661 gaactggcag tgatgcaatt gagcgaagag cagaaagaac tggtccgtcc gtttgctatc
     6721 ccgcggccta cccgtcagat tgtcctggtg acccggaaag acttcatccg caccagtctg
     6781 ctgcaggttt tgaaagagga gattcaggcg gcggttccca aggagatgct taccctgcag
     6841 gccgttcagt gcctggtata atataaaaac gacggcgata ttttcacaaa catcgccgcc
     6901 ttatttcttt tatgtatcag aattattact cgttttgcct gattgtgtag gtgtttcttg
     6961 ttgttttatt gagaatgaaa tgattttatt tttaaatttt tgtcttcgtt gatatctatt
     7021 gtgacatact gtatattgtc ataaatggtg ttcacacgga gttttattcc tttggctgtc
     7081 gccaattgct cggctatact atccagcttg aaagaaacaa ggctcgaacc caattgattg
     7141 ggggagtcat taaaggcatt atgccggaac tccagataga tatatccgtc atcttttatg
     7201 ggacctgtta tttcgttttg taccaagttc agcatgtgtt ttttattttc attcatgctg
     7261 cccagatatt gatattcgat ggtcagataa tctttcgtaa gtgcatgcgc tgtgacgttg
     7321 atacggtcgt ctccaatgct gtctgctgta gcttccgtca gtgggatgat ctctttcgtc
     7381 aatatatctt ctatcgtgaa tattttaccg ttctcatatc cgggcttctc ttttcccatc
     7441 tgcagatagc caacgaagac tctttgacct tctgcaacag tgtatttcct gttgcgtata
     7501 tcggccgtat ctgccggaag tacattgtct ccattgtcca acgcaatgaa aaagtccctt
     7561 ggagtgtccg cattgggaat cttcattgtg ccgatggcta atattccacc cggaggacaa
     7621 gtgacccact cgtcgttgtt ggcatcgtcc agacatgact gtaatatggg caataacatc
     7681 aggatgacgg caaaagttat taaattaaat ttcttcataa gtttcttgtt ggttttatcc
     7741 tatttatcca ttgagattta ttctttattg tattgaaaaa atgcaggaag tgatgaaata
     7801 ttgcatccta aaatgttaaa gaaacaaaag tgataaaaga gttgttctct ctgtgcagta
     7861 tttctatctt tgctgcattt ataaggtaaa cacgtgttta ggagaatgaa tgagttagag
     7921 ctgtcggaac gttgcaggca gggagataat cgtgcccgca aagaacttta tgagcagtac
     7981 gcagggcgca tgcttggtgt ctgtcttcgt tatgccggag acagagacat ggcacaagac
     8041 ttggtacacg acggtttcct gaagattttc gactccttcg acaagtttac ctggcggggt
     8101 gaaggctctc tgagagcatg gatggagcgt gtaatggtga atacggcttt acagttctta
     8161 agaaagaacg acgtgatgaa ccagaccacg gcactggatg aagttcccga aacgtatgaa
     8221 gaaccggatg cttcggctgt tgaagcaata ccacagaaag tgctgatgca atttattaat
     8281 gaactccccg ccggatatcg taccgtattc aatttataca cctttgaaga taagtcgcac
     8341 aaggaaatcg cacagatgtt ggggattaat gaaaaatctt ctgcctcaca gctttttcgc
     8401 gcaaaaagtg tattggcaaa gaaagtgaaa gaatggttgg tgaccaatgg ttgacatgta
     8461 tttacagata ctgaggtgaa ccttggattt caaaaatgaa atagaatgat gaaagaagac
     8521 gaaaaatgga ttaaagcatt caaggataag ctcgaagatt attcggagcc gatgcctgct
     8581 tccggttggg aacgactgga aagggaactg atgcctgtaa ccgaaaaacg aatatatccg
     8641 tatcgccggt gggcggttgc tgcggcagct gtggtattgg tggtaacgac tgctgtcagt
     8701 ttgtattttc tgaatagtcc ggtagctgat gaaatccgtt atgcaacgac tccttcactg
     8761 gctgtcaacc cggatgtatt gccggaacct gccttgccgg atgtacaggt agctgtatcc
     8821 gaacccgtta agccggtagg aacgacgagc atcaaccctg tttcgggcta tttggcaaaa
     8881 aatactgatc cggtgattgt tccggaggta tcctccctgg cagagaagcg accggaggca
     8941 gtgacggagg aaaagagagc tgagccgcaa caggaagcaa ctgctgcaat cgagaaaaaa
     9001 gaaagtgcga cggcgcagcc tccaaagagg aaagaagcgc ggcgaccgtc cggtaaagac
     9061 aagtatcagt tgcctatcgg agactcttct gctaaacgtg gtggtaaatg gtcgatggga
     9121 gtgggtatcg gtaatggagg tggacttccg acaaatggtt ccgaaaattt tgcgccccgt
     9181 ccgatgacta acagggtcga cttgatgacg atcatgaatg gagctgtgag tattcctgcc
     9241 gatcaggaag ttatatttga ggaaggggtt ccttacctga agtccaatac aactgccgtg
     9301 gtggattatg aacatcatca gccggttagc ttcggactgt ctgtacgtaa gtctcttccc
     9361 aaaggtttct ctgtagagac gggattgact tatacgttgt tgtcttctga catcaaacgg
     9421 cagggggata ccaagatgca gagtcagaaa ttgcattata taggtattcc tgtacgtgga
     9481 aactggaatt ttctggaaaa gaaatatttt acactctatg tatctgccgg aggaatggtt
     9541 gaaaagtgtg tttatggaaa gttggcggat gataaggtga atgtgaagcc tttgcaattt
     9601 tctgtagccg gtgccgtggg agcgcaattc aatgcgacag atcatgtcgg cctatatgtg
     9661 gaaccgggag tttcgtattt ctttgatgat ggctccaaag tacaaaccat ccgaaaagaa
     9721 aggccttgta actttaactt gcaggcagga ttgcgattca cttattaaag tagggtggca
     9781 aaaaatatgc cggttacatt atttccctgt tcttgccttg tattgtaatg aattgaggca
     9841 agaacaggga gatttttatg tcgtgactta caaaattata aataagcgca atcgtcataa
     9901 ttcaccgcag agtgaactta atctattgat ggccaatgaa tctttatctg tgtaaattcg
     9961 tgtaatctgt ggcgaatacg agtttcgaca cttatataag tcaattcact tgtacggtcc
    10021 ggaaatattg cctgaatagt ttctcagcct tttctatctg ctccggagta ttctctttca
    10081 ctcctttcag catatattct ttgttcattg cttcatattt gtgaacaccc aaggtgtggt
    10141 aaggcaatat ttctacacgc tgaatcatct ggtacgttcc aagatgctct cccagctgcc
    10201 ggatatcgtc ttcgaagtca ctgtagccgg gcactaatac gtatcgcaac cagaatggtt
    10261 tatgattggt ttcaagccag gctgcggttt tcagggtctg ctcgttgctt cttccggtta
    10321 aagactgatg atgttccgga ttaaattctt tgatatctaa taaaaccaga tcagtcaatt
    10381 ccaatagttc ctctacatca ttgttccata gcccgccatt ggtatcaagg caaatatgga
    10441 ttcctgcttc ctttagtctt ttaaaaagtg ggataagcga ttttgcttga aaagtaggct
    10501 ctccgccgga aaaggtgata cctccctttt taccgaagaa agctttctga ctgacggcca
    10561 tgcgaactat ttcctcaggg tcggttgctg tccctccttt ggcttcaatt gtgtccggat
    10621 tggcacaata gaggcaacgg aagttacacc cttgaaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccatt gactcgtatg agtgtacgtt tatcattcaa ttacattctt
    10741 tcgtggaaac tgcggctgat tacttccaac tgatgttcgc ggctcaattt cacgaaatta
    10801 acggcatatc ctgagacacg gatagtcagt tgcggatact tttcgggatg ttccatcgca
    10861 tcccgcaaca tttcccggtt cagcacgttt acgttcaggt ggtgtgcgcc ttttgtaaaa
    10921 tatccgtcca tcatggtcac cagattgtcg atacggtctt cttgtgttgc tcccaatgat
    10981 ttgggaacga ttgagaatgt attgctgata ccatcctgtg agtcgcgata acgcaacttg
    11041 gctacagaac tcagtgaggc gattgcacca tttttatcac gtccgtgcat ggggttggca
    11101 ccgggagcaa aggcaatgcc tttggcgcgt ccgtcaggag tggcaccggt cttcttgcca
    11161 tacattacgt tcgaagtgat agtcagcagc gaaagggtag gacgggcatt cttatatacg
    11221 gggagtttct ttaattcttc gctaaagaaa tataccaggt ccacacccag gtggtctaca
    11281 cggtcatcgt cattaccgaa acaagggaaa gcaccttcga tatcgaatcc ctccgtcagt
    11341 ccgatgtcgt tgcgacgggc tttcacatgt gcatatttga tggcggacag tgaatcgatg
    11401 gcgattgaga gtccggctac accataagcg aggttaatgc ggggatcagt atccacgaaa
    11461 gccatctgcg ccttttcgta gtaatactta tcgtgcatgt aatgtatgat attcattgct
    11521 tcgttgtata cacgtgcaat ttgtatcaat actttcttat agttggccat tacttcttcg
    11581 aacttcagtg tttcaccggt caatacaggg atgtctttta ccataactgt acctgtattt
    11641 tcgcaacgtc ctccgttgat agccagtagc agggctttgg caaggttggc acgtgcgccg
    11701 aagaattgaa tctgctttcc gatttcctga tatgaaacac aacaagcgat tccgtagtca
    11761 tccgattgac ggacttcacg cattaggtcg tcgttttcgt attgtacgga agaagtgtcg
    11821 atagatactt gtgcacagaa tgctttgaaa ccttcgggta actcagggct ccatagtaca
    11881 gtcatgttag gttccggtga cgggcctaag ttataaagtg tctgcaagaa gcggaaagaa
    11941 gttttagtaa ctttggtacg tccatcattg aaacgtccac cgatagattc ggtcacccat
    12001 gtgggatcac ccgcaaaaat atcgttgtac gactgcatac gcaagtggcg taccatacgg
    12061 agtttgataa cgaattggtc gatcagttcc tgagcgaatg tttcggttat cgtaccctgg
    12121 cttaattcat attcaagata gatgtcgagg aatgaagata cattacccag tgacatggca
    12181 gcaccatcct gctcttttac ggcagccaga taagccatat acacccattg tacagcttcc
    12241 tgtgcggtat atgccggtcg gctcagatcc aaaccataat attcgcccaa tactttaatc
    12301 tctttcaggg ccttgatttg ctcggctact tcttcgcgaa gacgaatgcg ggcttcagtc
    12361 ataggacctg tcagattatg cagatcttct tttttagctt ctatcagacg gtcaagacca
    12421 tagagagcca ggcggcgata atcaccgatg atacgtccgc gtgcatagtt gtcgggaagt
    12481 ccggtaagga atcccaatga acggaacgaa cgaatttctt cggtatacac atcgaatacc
    12541 ccatcattat gagtcttgcg atagtgagtg aagatatcct taactctgtc atctacttcc
    12601 actccgtttt cacggcaagc tttcataacc acattgattc cgccaaacgg tttgatggca
    12661 cgttttaaca cctgatcggt ctgtagtccg acgatcagtt cgttctcttt atcgatgtag
    12721 ccggcagggt gagaggttat agtagataca gttatgtagt cgagtgcacg aataccatta
    12781 ttgtttctct cttcttcgag agctttgaga cagtgattcc agacagcttt ggtgcgttcg
    12841 gtaggtcctt gcaggaaaga agcatcccct tcataaggag tgatgttgtt actaacgaaa
    12901 tcccttacat tgatttcttt gctccaaagt ccatctttaa aggtcttatt cagttccata
    12961 aaattaatca gttagtggtt agttatcctt tagagcgcgc aaatttacaa ccttttttcg
    13021 gtttaggtat ataaaagggt cctattttat gttgaatagc ataaaaatac ctatttatgg
    13081 ggagaagcta gatagcagtt attacttcca aatatacttt tctaatattt ttttgcggaa
    13141 taatttgcaa gttaaaaaat gattcgtacc tttgcagcgc tttaagagaa aagcactact
    13201 taaccgtagt tctggagagg tggcagagtg gtcgattgcg gcggtcttga aaaccgttgt
    13261 actgcga
//
