LOCUS       c00027_gnlPro..        16530 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ECENHJGB_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:11:03
            Original ID  :: gnl|Prokka|ECENHJGB_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16530
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16530
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3112:6670](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3113..6670
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16530
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16530
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(540..1694)
                     /locus_tag="ctg27_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1874..3079
                     /locus_tag="ctg27_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3113..6670
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6795..6983
                     /locus_tag="ctg27_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6994..7854)
                     /locus_tag="ctg27_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7882..8712)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg27_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8709..9935)
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10408..11694
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11657..11989)
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12017..14770)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15103..16329)
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 taaactaatt cagttataac aaacgaagtt gtcaactaaa accagtacac atcattccat
       61 tgcttgaaac cagagtttca tcggtgtgaa actgtagttt catcggtgag aaactagagt
      121 ttcatacgct tgaaacttta gttccaaacg ctcgaaacta tctgaaacta ctgttgattt
      181 gattgactta accgcatgtt ccaatcacat tgaacgcatc agctacttca atagtactgc
      241 tctctctgaa aacattaaat catatatcag tcaataatac ataaattatc agtccttaat
      301 acttgatttc tcaattatta atatctgaga aatcaaacgt taacagttga gatatcagat
      361 attaacatcc tgtaaatcaa agaataacac agtaaaaacg gtatttatca ggacgatgca
      421 gagtgagagc aagtccttgc tctcactctg ctaccactgg atctctaaca gctaaaacat
      481 cgatgaataa agggatacag acgaactgtt agagcatgag agcaaaagca ctatcttttt
      541 cactggggga gagtaagcaa aagaaacgca cgataccggc tttgaggcgt caccggtact
      601 aacggcaaat atccggcaca cacccgatta ttctctacgg acaaagggaa cgaagccgac
      661 atctgccgat gttcctccaa agcctgaccg gctaaaggat aataatcaat ccgaaaaact
      721 ccttccgcat ccgcagccaa ataacgatcc gtcaagagcc atgccaccac ccccatattc
      781 attcgcagat taatttcgac acaaggatga atccggtaaa caggcgcttc atccggaaaa
      841 tgacaaatca tcatatccac tcccaagtat ccatgataaa agccaccgaa caaagctgac
      901 aattcttctt ccaaacgagt ccgcagcctg ataaattctt cttgtggcac ataagccgat
      961 agtttctgca gaatcttctc gtcagacagc aagtcattcc ctgcatacat cccactccca
     1021 cccgtgtgga agaccgaata tccggcaaaa acaacccttc ctctcccgtc agcataaaac
     1081 tccatagcga aatcttccac cttattatat ataggttcgc ctaccacccc accctgagaa
     1141 gcagcgacac gggcacacca accggaaata aaagtagtaa atatgccttt acaccaattc
     1201 aatcctttcc cgcttccgga aagcggagct tttaacaagc acgcttcccg cccttcgacg
     1261 aacgcactgc actccgccaa agtactcaaa taaaaagatt ctccacagaa gtattcattc
     1321 aaccgcaacc caggcaacaa ctttaccgcc tgcagacgat gcgaatgctc tctcagaata
     1381 ttcatataat ccgcagaagg cagctccgtc tgacctgccc ccaatgtcat caaacgcttc
     1441 cgcaaagcag ggtcccaacc ccacggagag aacttccggt ctttaccgtc agccacttcc
     1501 ggttccgtca acaaggccac atccatgccc aaaagttcac tctttgtttt caggaagtcc
     1561 gcattataag cagacggtgc aagcaccgca cttcccgctt cggcatacca cataggaagc
     1621 aacgccaggt cactcgccat ctgtcgggcg gaagccggcg ccatatagtt cgtctcaccg
     1681 cttgccaacg ccatatcatg ctccggattg aatatataaa caggtctttt cgtcatgtca
     1741 aagatggatt caacacatta ttctgcaaat atatacagga aataatcagg aacttacaca
     1801 ataaagagaa acttataaat taaagcacat ttttgctatc tctactttgc aaatcctaaa
     1861 aaaagcacta tatttgccag ccgaaaaaca aagaaacgaa atggaatcat tctatcgcac
     1921 acacgcctac ctcgttgagc acaccaatgc ccccgttcgc cgcgatctta tggacgagat
     1981 cgactggagt gaccgtctga ttggtatcaa agggacacgt ggcgtaggaa aaaccacttt
     2041 cctcctgcag tacgccaaag agaaattcgg caccgaccgt tcctgtctgt tcatcaatat
     2101 gaacaacttt tatttctccg gtcacagcct tgttgacttc gccaacgagt ttcagaaacg
     2161 tggcggaaaa gtactgctga tcgaccaggt gttcaaacat cccgaatgga gcaaagagct
     2221 acgaatgtgc tatgaccgtt tccccagcct gaagattgtc ttcaccggtt cttccgtcat
     2281 gcgactcaaa gaggaaaacc tcgaattgcg tgacattgcg aaaagttata acctgcgcgg
     2341 attctctttc cgtgaatttc tgaacctgca gacaggaatg aaattccggg catacagcct
     2401 cgaagaaatc ctcagtacac atgaacagat agccaaagga gtactttcca aagtacgacc
     2461 gctggattat tttcaggatt acctgcatca tggtttctac cctttcttcc ttgaaaaacg
     2521 taatttctcg gagaatctgc tgaaaacaat gaacatgatg gtagaagtgg atatcttgct
     2581 gatcaaacaa attgagctga aatatctttc aaagataaaa aaattactat atttgttggc
     2641 tgtggacgga ccgaaagctc cgaacgtgag ccaactggca agtgacgtac agacatcccg
     2701 cgctacggta atgaactata tcaagtatct ggcagacgcg cgtctgatta atctggttta
     2761 cccgaaagga gaagaattcc caaagaaacc gtcaaagatt atgatgcaca actctaacct
     2821 gatgtactcc atttatccgg tgaaagtgga agaacaggat gtactcgaca cgttcttcgt
     2881 taacacttta tggaaagacc ataaggtaca taaaggagat aaaaacgtct ctttcatggt
     2941 agacgaagtg atgccgttca aaatttgtgc ggaaggtaca aaaataaaga ataacccgga
     3001 cgtgacgtat gcgttgcaaa aggctgagat aggccgcggc aaccaaatac ctctttggat
     3061 gttcggattc ttatactaaa aagatttatt tacttaaata tttaatttag ttatgactaa
     3121 acagaagaaa ttcatcacat gtgatggtaa ccaagctgca gcacatatct cgtatatgtt
     3181 ctctgaagta gcagctatct accccatcac tccttcttcg actatggctg agtacgtaga
     3241 cgaatgggct gccgcaggac gtaagaacat cttcggcgaa acagtattgg tacaggaaat
     3301 gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct cttcaggctg gtgcattgac
     3361 tactacttac actgcttctc agggtcttct tttgatgatc cctaacatgt acaagattgc
     3421 cggtgaattc ttgccttgtg tattccacgt ttctgctcgt acactggctt ctcacgcatt
     3481 gtgtatcttc ggtgaccatc aggacgtaat gtcagctcgt caaaccggct tcgctatgtt
     3541 ggcagaaggt tctgtacagg aagttatgga tttggcaggt gttgctcatc tggctactat
     3601 caaatcacgc gttccgttca tgaacttctt cgatggtttc cgtacttctc acgaaatcca
     3661 gaagatcgaa atgttggaaa acgacgacct cgctccgctg atcgaccagg aagctttggc
     3721 tgaattccgt gcccgtgcac tgaatccgat gaagccggtt gcccgtggta tggctgaaaa
     3781 ccccgaccac ttcttccaac atcgtgaatc atgcaataac tactatgaag cagttcctgc
     3841 tatcgtagaa gaatacatga acgaaatttc caagatcaca ggccgcaaat acggtttgtt
     3901 cgattactac ggtgcagaag atgcagaacg cgtaattatc gcaatgggtt ctgtaactga
     3961 agctgcccgc gaagctatcg accacttggt agcaaacggc gaaaaagtag gtatggttgc
     4021 cgtacacttg tatcgtccgt tctctgctaa acacttcctg gctgctgtac ccaagactgc
     4081 aaagagcatc gcagtgcttg accgtacaaa agaaccgggt gctaacggcg aacctcttta
     4141 ccttgacgtt aaagactgct tctatggcgc agaaaatgct cctgttatcg ttggcggtcg
     4201 ctacggtctg ggttcaaaag atacaactcc ggcacagatc atctctgtat tcgaaaactt
     4261 ggctatgcca atgccgaaga accacttcac tatcggtatc gtagacgacg ttacgttcac
     4321 ttctcttcct cagaaagaag aaatcgctct gggcggtgaa ggtatgttcg aagctaaatt
     4381 ctacggtctg ggtgctgacg gtactgtagg tgccaacaag aactctgtta agattatcgg
     4441 tgacaacacc gacaaacact gtcaggctta cttctcttac gactccaaga agtcgggtgg
     4501 tttcacttgt tctcacttgc gtttcggtga tactccgatc cgttctactt acttggtaaa
     4561 tactccgaac ttcgttgctt gtcacgttca ggcttacctg cacatgtacg acgtaacacg
     4621 tggtttgcgt aagaacggtt ctttcttgct gaataccatc tgggaaggcg aagaactggc
     4681 taagaacctg cctaacaagg tgaagaaata ctttgcacag aacaacatct ctgtatacta
     4741 tatcaacgca actcagattg caatggaaat tggtttgggc aaccgtacca atacaatcct
     4801 tcagtctgca ttcttccgta tcacaggcgt aatccctgta gatcaagctg ttgaacagat
     4861 gaagaaattc atcgttaagt cttacggcaa gaagggtgaa gacgttgtta acaagaacta
     4921 cgctgctgta gaccgcggtg gtgaatacaa gactctgact gtcgatcctg cttgggctaa
     4981 cctgccggat gatgcaaaag cagaaaacaa tgatcctgct ttcatcaacg aagtagttcg
     5041 tccgatcaat gcacaggacg gtgacttgct gccggtatct gcattcaagg gtatcgaaga
     5101 cggtacttgg tatcaaggta cttccaaata cgaaaaacgt ggtgtagctg cattcgttcc
     5161 cgaatggaat gctgaaaact gtattcagtg taacaagtgt gcttacgttt gtcctcacgc
     5221 ttctatccgt ccgttcgtac tcgatgctga agagcagaag ggtgctaagt tcgagcaact
     5281 gaaagctgta ggtaaagcat tcgatggtat gacattccgt attcaggtag acgttctcga
     5341 ctgtctgggt tgcggtaact gtgccgacat ctgtccgggt aatccgaaga agggtggcaa
     5401 ggcattgacc atgaaacacc ttgaaagcca gttggccgaa gctgataact ggacttactg
     5461 cgctgaaaac gtgaagagca aacaacacct ggtagacatc aaggctaacg tgaagaactc
     5521 tcagttcgca actccgttgt ttgagttctc aggcgcttgc tccggttgtg gtgaaactcc
     5581 gtacgtgaaa ctgatttctc agttgttcgg tgaccgtgaa atggttgcta acgctacagg
     5641 atgttcttct atctactccg gttcagttcc ttctactccg tacactatga acgaaaaggg
     5701 tcacggtcct gcatgggcta actccttgtt cgaagacttc tgtgaatttg gtctgggtat
     5761 ggaactggct aacgaaaaga tgcgtgcccg tctggtgaaa gtaatgaacg aagctatcgc
     5821 ttctgattgc tgcccggctg aatacaaaga agtatttgct gaatggatca acaatatgct
     5881 ggatgcagaa aagactaagg aactggccga aaagatcatt ccgatggtag aagctgctaa
     5941 agataaatgc aaccactgca agcaaatcgc tgatctgcaa caatatcttg ttaaacgcag
     6001 ccaatggatc atcggtggtg acggtgcttc ttatgatatc ggttacggtg gtcttgacca
     6061 tgtaatcgct tccggtaagg acgttaacat ccttgtattg gatactgagg tttactctaa
     6121 cacaggtggt cagtcttcta aagctactcc ggtaggcgct atcgctaagt ttgctgctgc
     6181 aggtaagcgt gtacgtaaga aagacctcgg tctgatggct actacttacg gttatgtata
     6241 tgttgctcag attgctatgg gtgctgacca ggctcagact ctgaaagcta tccgtgaagc
     6301 tgaagcatat ccgggaccat cactgatcat cgcttacgct ccatgtatca accacggtct
     6361 gaaagccggt atgggtaaga gccaggaaga agaagaaaag gctgttaagt gcggttactg
     6421 gcacttgtgg cgttacaacc ctgctttgga agaagaaggc aagaatccgt tccaactgga
     6481 tagcaaagaa cctaactggg aagacttcca aggtttcttg aagggtgaag ttcgttacgc
     6541 ttctgtaatg aaacaatatc ctgctgaagc tgaagaactg tttaaagctg ctgaagaaaa
     6601 cgctaaatgg cgttacaaca gctacaaacg tcttgccaga gaaaactggg gagctgatac
     6661 agctgaataa taagtagaaa tactttgtac ataataaaag gcaggaatcc tggaaacaga
     6721 ttcctgcctt ttttgtttat atcttagaag taacgattac ttctcacgaa gatattcatt
     6781 aaaactctaa agatatgatc ggatttgtta tttggattat cggtttgata ctgactttca
     6841 gagctgccat agagatttgg aatataaatg cggctgtaga gaaaagactt atagcgattg
     6901 tattaatcgt tcttaccagc tggctgggac tacttttcta ctacttctat ggtaaagaaa
     6961 gaatggcggg atggttgaag tagtgtttgc atatcaatct ttctcaggaa tccaactgtt
     7021 caccagttcc tgatgttctt ccatccattg acgggcagcc tgtctttccg ttgtctgcgc
     7081 ctcttccaga gcagtcatta aggagctgat ttccgcatct gtcagacgaa tgttgcccaa
     7141 aagttcggca gcaaaagggt ctttctcgct aaaacctttc catgctatgg tatgaatgga
     7201 ttccgtattt ccatatatca gcttcgggtc ctgaagaact ttcagcttga aacggtcgaa
     7261 catccagtga ggcgtccatc ccgtcacgac aatccagtct ttcttatcaa tcgctttctt
     7321 tagggaagca gtcatggcag gtccgctcga agtcatcagt ttataatcca atccatagtc
     7381 tttgatggcc tgatcggtag ctttcataat accggctccg gcatcaatac cgacaatctg
     7441 accggagaaa cgttcctttt ccgcgttcag ttcttcgatt gagttgatcg taacgtaatc
     7501 cggaaccacc agcccgatac gggcaccatc ataaatatcc ccgataactt cgagtttatc
     7561 cccgtattgt ttcatataat cttccatagt gacaggcatc cagacatcca taaatacgtc
     7621 tgctttctta cgggagatag aggtaaatat aggtgcaagg tcggcattca gcaactttac
     7681 atcgtacccc tgatcttcaa aaatcgcttt ggcaaggttt gtcattgcaa taccttccga
     7741 ccagttggca taagcgatac ttatcttctt actctttccg ttgtctccgc aggaaacgaa
     7801 ggttaagagt atgccggcaa taaacattgc cgcaatcatt tttatcttat tcattgatta
     7861 ttcctttctt tggtgtgatt cttatttctt tttacttttt ctgttatctg ccataccctg
     7921 agtgatgcgg tccagcacga tcgccaatat cacgactgcg ataccgcctt caaatccgag
     7981 tccgattttc atttgggtga tacctttcag cacgatttct cccaatcctc cggcagaaat
     8041 catggcagca atcactacca tcgaaagtga catcatgatc gtctggttga ttcccgtcag
     8101 aatagtaggc aacgccaaag gcaattgcac cttataaaga agctgccagg gagtagctcc
     8161 aaaagagcgg gaggcttcta ctacgttttt aggaacctga cgaatgccca gaccggtcag
     8221 acgaaccaca ggaggcattg caaagatgat ggtggcaaaa gctcccggca cagttcccaa
     8281 tccgaagaat agaacggcag gaatcagata gacaaaggca ggcattgtct gcataaagtc
     8341 gaggacaggg cgcattatct tgttacaacg atcactgttg gcagtccaga ttcccaacgg
     8401 aacgcctaaa agcaatgcca gacaagtgga agaaagtacc aatgccaatg tctgcatcgt
     8461 ttcttcccaa aagcccatgc cgtaaataag caataaaccc aagagggtaa atacggctgt
     8521 ccccttaccc gacttaaacc aggcgagcgc agccagcact gcaattgtga tataaaaagg
     8581 tattccaaac agtacgtgct gaaaaccgtc tatgaatcct ccgatcccca tgctgagagc
     8641 atcaaaaaag gaagcaaaat gttctgtgag ccaattaatg gcagtctcta tatattgtcc
     8701 gatatttatc ataattctat tgcgttttga atgatttcat taatttcttc tttatctttt
     8761 cccgttactt cgatgatcaa tgaggaaagt ggcactacgc cttcaaactc ccgattctca
     8821 tttacgaccc agattggcga gttcgttttt gtcatcaacg gaagaatatc ttccagcacc
     8881 gtatcaccca gcactgaatg aacttcatgc cttactacgg actcgatgga gcggatttgc
     8941 tcttttcgta gtttcagcaa gtcattcaac cgcacctctc ctactaacag attattggaa
     9001 tcgactaccg gaagaacggt cagattccgt tcgcgcatct tacggatcag cacctccggg
     9061 ccttctttct tcaaacgtgc cactatgggt ttatctacca taacagagga agctgttata
     9121 atcttgcttc gatctacatt ctccacaaat cgttctacat aagcgttggc aggttcggtc
     9181 aggatttctt ccgatgtacc gatttgtaca atttctccat ccttcatgat agcaatccgg
     9241 tcacccaatt taatcgcttc actcaggtcg tgagtaataa agacaatcgt ttttttcatc
     9301 ttcgactgca aagtcagcag ttcatcctgc atctgcacac ggatcaaagg atcgagtgcc
     9361 gagaaggcct catccatcaa caggacttcg ggattattgg ccaaagcccg cgccagcccg
     9421 acacgctgct gcatcccacc cgacagttca cttaccatct gattctcgta gcctttcagc
     9481 cccaccagtt gcatgctttc catcgctttc tgctcccgtt ctcccttttt tactccctgt
     9541 agttcgagcc cgaaagctat attatgcaag acagaacggt gaggaagcag accgaagttc
     9601 tgaaagacca tagccagttc tttccggcga atctgcaaca gttccttatc cgacactttg
     9661 gctatgtctg ttccattgat aatcacttct ccggaagtag ggcgtatcaa acggttgatg
     9721 cagcggagta aagtggactt tccactaccg gacagcccca taatgacgaa tatttcgcct
     9781 tcattaatgg aaagattcgc atctttcacc gcaactgtac atccggtcgc tttcaatatt
     9841 tcactttttg ttttaccttc tttcaacatc ttcaaagcct tctgcttctc attgccaaaa
     9901 accagataga gatctttaat ttctatttta ctcatacaat aaaatggttt aggttattaa
     9961 aataatatac acagcaagac aagaacaaac gataacagga atctttcttt atatcgtata
    10021 aagttctgat ttaaataagg gacaaataac aatgaatccc gaaataatta ataaaatgat
    10081 tattgacaga ctgagtaatt aaaaaaggaa tagaatttga taagataatc ctttcaacga
    10141 atagcaaaaa atagcatttt tatgtataaa aacagcctgt tccagtatct tgctggcaca
    10201 aagatacaaa aaacggatta aacatacaaa ttatattcaa aatccggggc atacagaggg
    10261 ctttatttgt aatgatatgg aaagtttccg ggtaatattc ccctatcact cagcaaaata
    10321 gaacaaaccg gcagataaat ataaaataag tttgaatatt tcacttaaac accgtatatt
    10381 tggcgtcaat aactaaacta gatttatatg ttcaacaggg ctattacaat tttcctgggg
    10441 aaggataatt gtcattacac aacaaaagaa aaacaaacag gtactgccac actagacgac
    10501 aaaagccaag tacagttcct tagtaaaaag aaccccaaaa tgccgttttt ctatagccgg
    10561 cggaatctct acatgatagg tttcctgctc gcttttatag tgactctgct cgaatttata
    10621 cgaggacggc atcaaaactt tatggtcttc tcggacgcta ctcaattctt ctggcaaggc
    10681 atcagcccat acacaactga atttgtagaa gctcacggac gctacttcct ttattctcca
    10741 gttttcacgg tattgttcgc tccgtttgcg tatctgcctg catggctggg acctttcgcg
    10801 tggaatctat tcaattattc gctgttcttt atggcgatct tcacgctgcc ccaacaattc
    10861 acccagcagc agaaatgccg tatgttcctt tttctgttac tgattttagg acaaagttta
    10921 ctttcatttc agtataacat aacggtagcc tatttattct tattcgccta tacgttattg
    10981 gaaaaagacc gtggatttct ggctgttctg ttaatcatga tttcgggatg taccaaagta
    11041 tatggaattt tcgaactggc attgttgctg tgctatcctc acgtatggcg taactttggc
    11101 tatgccgtta caatgggcat tgtattgctt gcattaccgt taataaaaat agctcctgca
    11161 gatttgctcc cctattatga agaatggtgc catagtcttg ctgttcatca gtccgccgga
    11221 gcttatgatt catttttcta tgcccgcccc attgcagcat ggacattgcc acacttccgt
    11281 gcacttcaga taggaatgct cggcttgctg actctgctct ttttggggaa tttccgcaaa
    11341 tggtcgtctt ttgccttccg tgcccaggct ttgggcattc tcatgggctg ggtagtatta
    11401 ctgagtgact ccgccgagaa gcatacctat attatcgcat tggcaggttt catgctctgg
    11461 tattggagca gaccaacacg taccgcaaca gacaagattc tattttggtg ctgttttgtg
    11521 ctgttatgta tcgttcctat cgacatattc gtccctgtac ccatcagaga tttcattacc
    11581 aggaccttat ggcttcatgt atgggttttc tttattgtat ggatacggat gatatggctt
    11641 accttccttg catccttcat tcatccacgt gccacaaatg ttctttcaga ttaacgcatc
    11701 cgttagcttt gaaagaaact tcttctgcca gcaagagttg tttttgttcc acccaaccgg
    11761 gcaccagcct tccggtggaa tttacaactc tatggcaggg aatggataat tcatccggca
    11821 cttctttcaa tgcacgtccc accatccgcg agcattgggg tgcccccaac agcaaagcaa
    11881 tacctccata agtagatact tttcccacag gtatctggga tacgacttcg tacacttcct
    11941 tccgaaagga ttcggaaaag ctctctttat ctactttata atctttcata tatccctctt
    12001 tacgatatca atgaaatcat cctttccttt tcaggaaatc tgtcgggctc tctccaaact
    12061 gctctttata gcacttggcg aaataagaag gtgaactgaa accgacttca taaccaatct
    12121 ccgctacggt catgtccgaa gaagcaagca aagaagctgc cttcttcaaa cgggcgatac
    12181 ggagcaattc attcggagag tagttagtca atgatttaat cttgcgataa agctgcacac
    12241 ggcttagtcc catgtctttg cccaagtcct ccacattcaa accggagtct cccattttct
    12301 cttcaatcaa tgacttgaat ctttctacaa aatccttgtc catatcgcag acatcttctt
    12361 ttgccaatgt ctgcccgtca ccaaagaact gtttcagacg acggtgagaa tcgatcagat
    12421 tgcggacacg tgccagcaac agctgtgaac tgaacggctt tgaaatataa gaatccgcac
    12481 caccgtcata tccctgaata cgctgttcgt ccagtgaaca cgctgtcagc agaataaccg
    12541 gaatatgaca ggtctgtaac tcacttttca gccggcggca acattcaatg ccatcaatgc
    12601 ccggcatcat cacatcagaa atgatcaggt ccggaacata cttcatagcc ttacggattc
    12661 cttcggagcc gtctgccgct tcaatcaccg tatagtctgt atgcaacagc gtatggacat
    12721 acgaacggat atcctcatta tcatcaataa tcagtacgga cggtttggaa gagtcatatc
    12781 ctttttccag ttcttcctct tctgccaata gaacatctgt tgtacgggaa tccgcagaaa
    12841 caagggtggt atccggttcg gcagcaacag cctcacaaga ctgtacaggc agttcaacgg
    12901 taaagaccgt gccctgtttc tcatcgctct ctacggagat cataccaccg tgcatttcta
    12961 cgaaggcttt taccaatgcc agtccgattc ccgaaccggt atggtgcata tcaatcttat
    13021 agaaacggtc gaatacattg cggatatgtt cggcagaaat catggaaccg gtatttgcca
    13081 ccgtgaaacg tatccatcgc ttgtcctctt tactaaggga agacagacgg atggctattt
    13141 tcccgttttc cggtgtaaac ttaaaggcat tggacaggag attgaaataa atacgttcca
    13201 gcttctccat gtctgccagt gtatgataat ccgtatccgg catactatca aaagaaaaat
    13261 ggatatgctt cttacgggct gccgcctgaa aagactcatt ccatccttcg aaagaagaaa
    13321 ggacatccac cgtaaccgga gtatattcca tcttgccgtt ttcatattta cggaaatcca
    13381 aaatctgatt gaccaggcgc aaaaggatat tcacatttcg ctgaatcagc atgagcatcc
    13441 ggtgctgatc tccactcaat gtcttgtccg ccaataaatg ttctaccggg tcggcaacca
    13501 atgtcaacgg agtacggaag tcgtgagaaa tattggtgaa aaagaccagc ttggcatggg
    13561 tagcttcttc cagttgatga gagagctgta tcaattggtc acgctgttct tccagtttgt
    13621 cacgctgctc ttccaattgc tgcttctgct taaaaagctc tttattcaag cgattcttag
    13681 agcggagtga tttataaacg accaataata aaccggctac caataaaagg ataatcagac
    13741 tgccgtataa aacaacctgt tgtgtagcta cctgagagag gtatccaccg atacgtccgt
    13801 tgagcgtttc aatcttttta tcgagttcgg agatgtgtgt agtctgcaac tgcatgacgt
    13861 gtgcgttggt acggtccaca acagcggtat tcatcaccgt ttctttggga tagggtttct
    13921 tctccagaat gtccatagcc agttgcagta ccttatcgcc attggtcgga tagataaagg
    13981 tggcatccag cacactgtcc aaaaccagtt ccagtccgtt tcccttaccc ggcaaggcat
    14041 ctatgccgac aaaaatcatt tccttctccc gccctgccat ctttgctgcc tgataggcac
    14101 ccggagcgat acggtcatta tgggcataca cagcatcaat cttaggatgc ctccgaagca
    14161 tactatccat ttctatctct gccggaccac gttcccacgc agcatccgct ttatcaatca
    14221 gctttatatc cgggaattta ctgatggcag ccataaatcc ctgatgccgt tccattgcag
    14281 gagtcgaacc gctcaatcct gtcagttcta ctatatttcc cttccctttc agactggagg
    14341 caatatagtt tcctaccgaa cgaccgattt cataattatc ggctccgata taggcagtat
    14401 atttatccga aagaatcttc cggtctacaa gaataacggg gatgcctttc tgataagctt
    14461 cttctacaat cggagtcata ggagcagctt cgttagcgga aataatcagc agatcgactc
    14521 cttcgtccat aaaataatgg acatcttccg cctgcttact gttatcatct cctgccgaac
    14581 ggatttccac cgaaacgcca ttataaaaca ttgcttcccg aagaatctca tcattcatct
    14641 tatgtcgcca tgaatcatcg ctgcattgag ccaccccaat acgaaaatgg ggtgtatcct
    14701 gccggcaagc cgtcatcccg attaaaccaa acagcaccag catccacttc agatatctca
    14761 tcgtcttcat ccatctcatc atttcatagt tctttctgta atccaattaa gaacaaaaat
    14821 aagaaataat actgtaaagt tctctaactt cagctattta ttattctaaa aagaaggaaa
    14881 gcagtcctct ttcagaccat cggaaagtat taacaaaagt ataaagcgta aaacaaacac
    14941 ttaatcaatg ttataaaaca tagcgtttta cttggataat ttgcagattt cacagaagtc
    15001 cgtatctttg cactgtgttt ttcatagtat tagatttaag gttaacaaag gttggagcaa
    15061 ggcgttgctc ctttttttat gccctgacct ttcatctacc ggttagtttt catcccattc
    15121 cttttccagt ttaccatcaa tagtgtagcg tttccatcgt cctacacggc gaccattctt
    15181 atattcccca cattcacgaa gctggtcatt ctttacataa cgagcttcga acggtccgtt
    15241 ctgccttccg ttcacatagg tagaagtttc ccaataatca aagcggttgc tcactatcag
    15301 ccgtcgttcc ttgccatgca atctgccggc ctgataggta gcttcatatc tcaattcacc
    15361 attttccaga ttatattcac ggtataaacc gtctttacga tcgttcttca tataatattc
    15421 tttctgcctt accccacttc cgttggcaaa tgagacatgg agtccatctt cttttccatc
    15481 cagataggtt tcaatcatca gcgtatctcc gctttcagca aaagtagtcc accgaccatt
    15541 cttctttcca ttcttataac tacccagtat acgtggcgag ccaaacgtaa acacggacga
    15601 atattcaccg tcctgcaaac cttcttcatt gaaataaacg gtctcataca aatcatatgt
    15661 acctttcaga aaagtatact gtttgcctac ctgcttcccg tccttgtaat tatgctcttt
    15721 ccgcaaagta ccgtcagatt cgtacgacag ttgcttcccg tgctctttcc ccatccggaa
    15781 gtttctttca ctttccactt ttccggtagt aaagtaactt ttgctcgtac cgtccagctt
    15841 accttcctta taggactttt cttctttcag cttaccgtca aacttggagt taatcttgaa
    15901 gaggccatcc ttccgccctt ctttataact tccttccgtt attaatatat tgtccacata
    15961 ttctttgtat ccgccatcat aaaaaccatc tttaaaagat gccagcacat aggcggaatg
    16021 ataaccatct atgatgcgat gttcgccatt caatgctttt tccgttttca gttcctgaaa
    16081 caacagtctg ccatcgccta cattaacaac agatacctga tcgatcttat attccttttg
    16141 cgcaaacaaa ggaagagcaa gatataaaaa caaaaatacg ttccagcttt ttgatctgag
    16201 gaagttcgaa atgtgtttca taaagtagtt ttctcttttt gatttattat ttaaaaacct
    16261 gccgcaaaga taggcaatcg gcttataaaa caaggcaaga aagaggggga caattagaaa
    16321 aaagaacatc tgttattatc attctaataa ttaacagatt aagtagtaaa tcaaaacaca
    16381 gggaaggggg acatttactg aaataagaaa cagaaaagaa gatgtgtcaa aagcaactaa
    16441 attcccctcc ttcaggaagg aggagagttt agttgctttt gacacattta catttgcagt
    16501 attaaatatc acaacaaaat ataagtgtat
//
