LOCUS       c00015_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IJLJMBDO_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:46:59
            Original ID  :: gnl|Prokka|IJLJMBDO_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 424867
            Orig. end    :: 449506
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[434867:439506]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             238..1752
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 266.7; E-value:
                     9.4e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_355"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-81, bitscore:
                     266.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSPQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDERIGIVAENRIETYAAILAVLTGGKTYVILHPAYPKERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKALSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYELTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSTLVLIHRPDGQIYYRTGDLCILDSDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1767..2009
                     /locus_tag="ctg15_356"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2013..3395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_357"
                     /sec_met_domain="MBOAT (E-value: 4.1e-21, bitscore: 70.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3414..4454
                     /locus_tag="ctg15_358"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRNSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNVLIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFVIGPDYY
                     QKKASREDIKILKAILGNSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4559..4951
                     /locus_tag="ctg15_359"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5144..5773)
                     /locus_tag="ctg15_360"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5757..6278)
                     /locus_tag="ctg15_361"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVADLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6299..7090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_362"
                     /sec_met_domain="F420_oxidored (E-value: 7.5e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVPHYGVFYPMQTFSKQREVDFKEIPFFIEASSTEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYAIAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7087..7419)
                     /locus_tag="ctg15_363"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7422..7919)
                     /locus_tag="ctg15_364"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8125..8667)
                     /locus_tag="ctg15_365"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8785..9768
                     /locus_tag="ctg15_366"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_367"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1e-22, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_368"
                     /sec_met_domain="CT_Btheta (E-value: 9.5e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_369"
                     /sec_met_domain="OAD_gamma (E-value: 5.9e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_370"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.7e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_371"
                     /sec_met_domain="OAD_beta (E-value: 1.1e-152, bitscore:
                     502.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14787..16118
                     /locus_tag="ctg15_372"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16132..17424
                     /locus_tag="ctg15_373"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVMLRAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17928..19778
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_374"
                     /sec_met_domain="Alpha-amylase (E-value: 2.6e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEDMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19936..20376
                     /locus_tag="ctg15_375"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGTEMEASRITECIEDLKRLHEVLNEI"
     CDS             20389..21456
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_376"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1e-10, bitscore:
                     36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKIRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21461..23056
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_377"
                     /sec_met_domain="MFS_1 (E-value: 4.8e-13, bitscore: 43.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAQTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIALLFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIVLFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23151..24155)
                     /locus_tag="ctg15_378"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gtatcaataa agtatcgtgt tgtctatccc attcaaagtc gtcggctatg aagccaacgc
       61 tatttcccct tccgaaaaag ggaaagcgag accgggcatg tgcgtaccac actattaaca
      121 ttctttaatc gattgtgcat agggagatca gaccatttca ctgtcatctt aataaacgat
      181 ctcaagaaga tatataaaga acccctaaac ccaaaacatg aataaaaact aatggatatg
      241 acaacatctc cccagaagga tattatcaat gatattcttt ccgccatgca atgttatccc
      301 gaaaacgaag cattcattat tgacgataaa cattatactt acgcccaact cggtgaaata
      361 acagcttcta tcacccattc gctatcagaa ataaaagatg aaagaatcgg aatcgtagcg
      421 gaaaaccgga ttgaaaccta tgcggctatt ctggcagtac tgaccggcgg aaagacctat
      481 gttatcctgc atcctgccta cccgaaagag cgtaatctca aaatagccgc tctggccgga
      541 ctgcgtactt tgctctgtac aagtgacact gaccggtcag cattcggcac cggacacttc
      601 agaatcatcg atacggaccg gctaccggga aaagcactgt cagaacagca gtcccattca
      661 tcggacgaag aaaggaacgc ttatatcatt tttacatcgg gaagcacagg cgagcccaaa
      721 ggagtgccca tcacacgggc taacttgaac gccttttacc gggcatacag ttcgctcgac
      781 tggaatctgg atgaacatga tcgcatgttg caaatgttcg aacttacatt cgatgtatcc
      841 gttgtatcct tactgtatcc tcttacttta ggtgctgccg tttatacggt aggccatcag
      901 gatgtaaagc acttcaaggt gtttgaactt ctggagaagt atgaactgac ctttgccact
      961 gtcactccct cactgctaca actcctttca ccctacttcg atgaaatcaa tctgccctct
     1021 ctgaaatatc tgggagtatc ggcagaagca tcgcaaaccg agctgttgga gcgattcaga
     1081 aaatcggcac ccaacgcaac gttcatcaac ctatacggac cgaccgaggc tacgatttac
     1141 tgcacctgtt accgtattcc ggcttcggac aaatgcaagc attacaacgg aatggtggct
     1201 atcggaaaac catttcccgg catccgcgcc atcattgccg acgaagaagg aaacgagcta
     1261 cctcaaggag agacgggaga actttgggta tccggccggc aggtaatgaa aggttatctg
     1321 gacgacccgg aaaaatcgac attggttctg atacaccgtc ccgacggaca aatctattac
     1381 cggaccggag acttgtgtat tctggatagc gacggggata ttatttattg cggacgtaaa
     1441 gactatcagg tgaaaataca gggtttcagg atagaactga gtgaaataga atatactgcg
     1501 cagtcgtttt tcaagactcc ctgcagcgtg gctgccgttc cgttgctctg cgacggaatc
     1561 tgtaacgaat tacatctggc cgtcgagaca actgaatgta cccaaagcgc attgatagaa
     1621 tatctgaaag aaaagctgcc caaatacatg ctgccgaagc agattcattg tatttcccaa
     1681 tttccggtga ccaatagtaa taaaacagac cgtaaaaaga ttgccgaact gataaaagag
     1741 aagaaactct aaaaacaata ataaatatga atcgagaaga agtattaaaa caactacaaa
     1801 gcattttccg tgatatctta aaaaaggaca acgtatgtat cgacgaatca tctacctcaa
     1861 aagatgtaga tggctgggac tcgctgaccc acatgcaaat tatagctcaa atcgagaaac
     1921 atttcggagt acgtttcaat ttcagggagg tcattaagtt caagaatgtc ggcgatttgt
     1981 gcagtgcctt attaaccaaa atggaataaa cgatgcagtt cctctctttt agtttcctgg
     2041 ccctgtttac cctctgtttc ttcctctact atgcagtcaa aggccgtgcc cgcaacctta
     2101 tactactggt aaccagttgt attttcatcg gatggtacta tctgcctttc ctgttgacgg
     2161 cagtagtggt agcactgttc accttctttt gggcacaatg gatggaaagc agggcaaaag
     2221 ccggaaaaaa gaccaaaccc gtctatatcg caggaatcat cgccctgatc ggcggatggc
     2281 tccttcttca tggcacggtc atagatgata tcatctttcc acttgggatg tcattttaca
     2341 catttcaagc catcagttat ctgacagacg tatactggca agagcaacgc agcgaaagaa
     2401 actgggtgga tttcctgatc tatatgcttt tcttcatgaa gtttctctcc ggccctatcg
     2461 aacggggtgg agacctgttg ccacaattga aagatccccg cccgttcatc tactcaaacg
     2521 cggtgaccgg actgaaatat attttactcg gactgatcaa gaaactgctg atagccaatc
     2581 agatctcccc acaaacagat gtcatgtttc attcgatcca tgacctctcg ggtgtacaac
     2641 tgctaatgac ttgcctactc taccctatcg aactgtatgc cgatttttcg ggttatacgg
     2701 atattgctat cggaggggcc tatatgttcg gcatcaagtt gtcgcccaac ttcaaccgcc
     2761 cgtttgcagc acgctcgact gccgacttct ggcgccgttg gcacatgtca ctctccttct
     2821 gggtacgcga ttatctctat gtaccgctaa ccgccggtac ccgtaactgg ggacagtggg
     2881 gaatctactt cagcctcctc atcacctttc tcgcattggg tttgtggcat ggggccggat
     2941 tgactttcgc catatacggc ctgattcagg gtgtccttat ctgctgggaa atgaaaacag
     3001 ctgctttccg caataatctg ccccaatata taggaaaata tgcggccgac agcttgctga
     3061 ttgtccggac ttatctattg ttcgcactct cgcttatatt ctttcgtgta caatcgctga
     3121 gcgatgcctg gtatttctta cggaacatct cgttcgaggt acattcttcc tggaaagaaa
     3181 tgaacatcgg catacgcgat cataattgca tcgtagcagg ttcggcccta ttactggtat
     3241 tgatctacga atattatgca tctaagtaca acctgatgga aacacttgaa cgccaacccg
     3301 catggttacg gtggagtgtc tactatctgt tggtattcgc tctgctgatg ttaggcaaat
     3361 ttgacacgga aactttcatc tatttacaat tttaaccgaa accctttacg cgcatgctac
     3421 atcattcatc gagaatctcc cccaagacac gtttttgcct gaagttgctt ttactgatcc
     3481 tgccgctgat cccgatagtg gttgtctatt ttatgtttga tccttatagg gtattacacc
     3541 cctacaaacg attcgacgac tctcccatgc tactcaacga agcccatgtg ggatggcaga
     3601 attatctgca gaatcgcaat tcgatagcct ataactcctt tatactcggc aactcctgta
     3661 ccatggcatt cctgacagga gaatgggaaa agtacctgga taagaacgac catgccgtac
     3721 gcttctatga caacggagaa agcctgggcg gcgtccgtca aaagcttcag ctgctcgact
     3781 ctgtaggtgc acccctgaaa aatgtactaa tcgttctgga taaaaaatca ctggacaaaa
     3841 acgctccttt atcgggcaac aatcatctgt tttcggccga agcagccggc atcagccaat
     3901 tgggattcca gttgagattc ctgcaggagt tcctttatcc ggacagaatg attccttaca
     3961 tagattatct gatccgacat aagtatgctc cttatatgaa aggggttata aatccgggag
     4021 atcccgtcag ggagccttac acgaacaatt ttatcaatcc cagagaaaaa gagatcgcgc
     4081 aagatggcga aatatactgg agccgtcatg aaaaagaatt caagaagcga acgaatgcgg
     4141 gtatggaaga acttcctgtt atatttgcca gccagattca ggtacttcgc tccataaaaa
     4201 aaatctgtga taagcaccac acgaacctga agttcgtcat cggtccggat tactatcaga
     4261 aaaaagccag ccgggaagac ataaaaatat tgaaggctat actgggtaat tccgctgtct
     4321 gggatttcac gggaatcaac gaatacacag ccgacataca tcattattac gaacccggtc
     4381 attatcgtcc gctgctggga gcacgcttac tgaaagccat ttatcaggat caagacacct
     4441 gccacaggca ataaaagttc ctcccataac agtagcacac acagaagaag agcatcctcg
     4501 atccgaaaga aataattata tcaaagaaaa caattatatc acattaaaaa cttagattat
     4561 gaaaaagatt ttattattgc tatccgtctg tatttcattt tcatcatgct gtacattatt
     4621 cagcagttcc aaacaagata tcacctttac gggaatgaat ggaactaaaa tctacgaagc
     4681 atcgaccaaa cagaaaatag cggaaatcaa agaagacaat agtgtcactg tacaaattaa
     4741 aaagaaaagg gaagacaaac aactagtagc caaaaaggaa gggtaccaaa cgactccttt
     4801 tgtcctggaa tctacattta acaatgcctg cctgtggaac attctatttt ggccgggctt
     4861 tctggtagat ttgggtacgc aaaagatgaa caaatgggat aacacaatta tcaatatcga
     4921 aatggagaaa gaaaatacag aaaacaaatg atcaaactat aatttcgcat ggcactcttc
     4981 tccttccacg gagggagccg ccatacggaa tcatgcgact tacaaggaag gcataattca
     5041 ccacaaggca acacagagtt ttttataaaa gttctttaga gaataaatct actctgtgag
     5101 actctgtgct actccgttgt atatacgagt ttcggcacac tctctatagt tgtttcaatt
     5161 ccctgtataa tttctgaatg ggaagtccca ttacattgaa gtagctgccg gatatggatt
     5221 ctactccgac aaaaccgatc cactcctgca caccatacga accggctttg tccatgggct
     5281 gatagtgatc gacataataa gcgatttcat cttcatcaag aatcgcaaaa cggacatccg
     5341 tcacggcagc gaaacatttt tgccattctc gggtagtgag acacacaccg gtaatcactt
     5401 ggtgcgattt accggagagg ctccgcaaca tctctatggc atcctgcctt ccgacaggtt
     5461 taccgagcgc tttgccttca tgccagacaa tggtatcggc tgtgatcaaa agctcttccg
     5521 gtccgatcat cgactgatag gcggctgcct tctcacgggc tatgaaaaga ggaatctctt
     5581 caccttgcaa cgtatcggga taagattcgt ccacatccgg caaagttttt actacataat
     5641 cgacacccaa gcccgtcatc agttctttcc gacgcggaga attagaggcc aatacgattt
     5701 tataacgatc taagttagca agcatactga taaataaata aggtatatac tggaaatcac
     5761 catccgaaag catcatcgga caaccattgg ccttgtgctt taagcacctg ctccaccaca
     5821 tcgcgtccac agccgtatcc tccatcggca tacgaaatgt aacgggcaat cgctttcacc
     5881 tcgggaaccg catctttggg acagcagggc aatccgcact cacgcatcac ttccatatcg
     5941 ggaacgtcat cgcccatgta gagtatctcc tcgtccgtaa gtccgtgttt gtcacggaaa
     6001 ccacgataat cgtgtatctt caccgcagag ccgaagtaca gatcggctac ccccaacccg
     6061 ataaaacgtt tccgcacgac atcgctccgc ccacctgtaa taatagcgat acgaagccct
     6121 ttttttacgg ccaattggat ggcataaccg tcttttacat ttaccgtacg catcggttca
     6181 cccgacggat gcaaagggat gacattggcg ctcagcactc cgtctacatc aaaagcaagt
     6241 gcttttatcc gggtaaggtc gtaattgatt gtgctcattt ttatttaatg tctcgggatt
     6301 attgtctttc gtgaatgctt cggctaagca actcgtataa ccgctgcatg gcaggatcat
     6361 cggcaagcat ccgcaagtga ttgccgatca cattctcgtc ataacggatg gccggcccgg
     6421 tctgggccgt cttaggttcc agttcgtgca ccttacgggc ggtttcatca atcaacggca
     6481 acatcacgtc aaacggcaga ttgtatttct taagcaactc agcagcaatg gcatacatgt
     6541 gattggtgaa attacatgta aacacggcag ccaagtggag acttttacgc tgctccgagt
     6601 cggcatcgta cacacggttg gacagtgtag aggcaatggc tttcagaaac gcggcatctt
     6661 ctgtcgaaga agcctctatg aagaaaggaa tctccttaaa atctacctcc ctctgcttgc
     6721 tgaaagtctg catgggatag aacacaccgt aatgcgggac atgtccttcc cagacattca
     6781 tcgggatgct acctgccgta tgcaccatca atgcctcttc ccgcttacct tcgacaatgc
     6841 cctgaagaag ttcggcaaag gcggaatctt tcagtgaaac aatatacagc ttcgcatacg
     6901 ggttcacctc tgcgaggtct gtcgtatatt cggcttccac tttctgtgcc agctcgcggg
     6961 ccgactcttc cgtacggcta tacacctgta cgatacgaaa acctttccga tataaggctt
     7021 ttgccagatt agtggcaaga tttccggcac cgataaatac gatcggcgta tcttctatac
     7081 ttcttttcat cgtgttgaaa tcaaatacaa tatacctccg attatcaata aagccaaagg
     7141 cagcagataa ccggacatcg aaccaagcaa cgaaacaatc aggccgatgt tcagcaccaa
     7201 ccacaatccg agcaatacca agccgacgga tttatcccgc ttaataaaca ggaaaatcac
     7261 cgcagtgtaa agcaaaagat tatccttatt catcacccag ggtatcccca aagtggaaaa
     7321 gtgtatcagt ttgtcgatca gatagagcac ccccatcaca ataagggtga ctgctgtggc
     7381 tttgtaggta tctttattgt ttgcttttac cgcactcacc gttacttacc tccgaactta
     7441 ttaatatgga ttttttccca ttgcaaatgg tcttcattaa agggtttacg ttccatccct
     7501 ttatgcccga tcgctatgac ggacaacacc tgcaactgca aaggaatgtc gagcacaccg
     7561 cgcacaaatt catcggaagg catcccggtg gcagtatatc gctcacgcac ctgcacccag
     7621 caacttccca atcccaagtc ttcggcctga agctgaatca taatagaggc aatggaagcg
     7681 tcctcaatcc atacatcgct cgccaaggga tcggcagtaa cgacaatggc caatgccgcg
     7741 tcggcaataa aggccgaagc ctgctctttg caatgtgaaa gttcactgag caacttttta
     7801 tcatcgactg caataaactg ccaactgtta ctgcgctttg aagtaggagc catcagggcc
     7861 gctttcagca aagcgactac atcttcctga gaaagttctt ctccggtaaa tttccgcatg
     7921 ctgcggcgat tttttattag ttcactgaaa ttttccatgt atctatactt tgcattattt
     7981 gaatataccg ccagtcacca tagaatgcac aaacacacgc gaaccgaggt accgcccggc
     8041 atgcccgtct atataaggta tgccctgcag gactttgcat gaatcggcgc gctccgtggc
     8101 gattcgagcg caaagatagg caatttattc cactctcgtc aactcgccgg tcagtgaatc
     8161 gatgataaaa ccatgcaccc ggacatcttt cggaataagc ggatggttct ctatggaacg
     8221 aaccgtgccc ctgacggact tcaccggatc gtcgaatccg cccagccacg aattaaaatc
     8281 gaccccgcag tagcgtatca tgtcgattgt ttcggacttg attcctcgct ttttcatgtg
     8341 agctatcatt tcgtcgctgt tcatgtggca agcaccgcaa tcagaatggg caatgaccat
     8401 cacttcttct actcccaact cgatgatagc caccagcaga ctacggatga cactgccgaa
     8461 aggatgggaa atgacggcac cggcattctt tataatcttt acgtctccat tgtgaattcc
     8521 taaagcggcg ggcaacagtt ctgtcaggcg ggtatccata caggaaagga tggcgatttt
     8581 cttatcagga tacttgttag tgatatactt ttcgtatccc ctgttctcaa cgaacttttt
     8641 gttgaattca agaatttctt ctaacataat caaaaacgga ttttattgta gtatctccac
     8701 aaagatagtc acaaaacgac agctcaacaa aataagccct gcaaatgttg taaagagaaa
     8761 taaaaaatgt aaatttgtcc cgatatgcca ttaaaactga ctacatatta ccaaggaagt
     8821 gagattccgg attttcccgg aaccaatacg tttcattcaa aagagctatt tcagatctac
     8881 gaagaaactc cgggctacac cccgcttctg attatggctt cggaagacgg aaaacctgtt
     8941 gcgcgactgc ttgctgccat ccgcaaaagc atccgcatgt ttcctcccgc tttcatcaaa
     9001 cgctgcgaaa tctatggcac gggcgaatat ctgatagcgg aagccgacaa ggaaaggata
     9061 ttcggcgaaa tgctggagca cctcaccacg gaggctttgc ggaactcgtt tctgatagaa
     9121 ttccgcaatc tggagaacgc catgttcggc tacaaatatt tccggtccaa cagatacttc
     9181 cctgtcaact ggctgcgggt acgaaactcg cttcacggca tcgaaaacgc cgaacagcgt
     9241 ttcagcccct cccgtatccg ccagatcaaa aaaggcctga aaaacggagc aaaagtagac
     9301 gaggcacgta cggtagaaga gatacgcgaa ttttcgaata tgctgaggca tctctattcg
     9361 tcccgcatcc gtaaacattt tcccaacatc atctttttcc aacacatgga cacccggctg
     9421 attcacagcc ggcaggcaaa gattttcatc gtccgctaca aagacaaaat tatcggaggc
     9481 tctgcctgta tctattcggg aaacgatgcc tatctctggt tttcgggagg tatgcgaaag
     9541 acctatgcct tgcaataccc gggtatactg gctgtatgga aagccctcca ggatgcccat
     9601 caaaacggat tccgccacat ggagttcatg gacgccggac tcccatttaa gaagcacggc
     9661 tatcgtgact tcgtgctccg cttcggtggc aagcaaagca gcacccggcg atggttccgt
     9721 ttccgctggc aatggctgaa cgacctgctg atcaaaatat acgtctgaac atccgcctgt
     9781 ctcagggatc agcgccaacc ctctccgcct tttaaaccac ctcccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc ctgttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccgggt
    11641 acgggtcagg aatataatgg tgtaatcctt cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatc gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagctgtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc aatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gaccatcaac aaagtgaaac
    12961 gcacctactc accctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccatagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcagc gctgatctcc aaccccaaat tgatgctgat cggagctgcc gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattggatt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatagtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaacc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccattgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggt aataagatca
    14461 atccgctgat cggtaatgca ggtgtatccg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt ttcattagta aagtagacgt ccttcttttc gcaaagaagg gcgtcttttt
    14701 ttgcgttaat ctatctaaaa gatattacga acctttcgta gaatggatat ttttactaac
    14761 ttgcggacaa taaagcaata cgtcctatga gaacaagaac aatgaaacca ctcttcctta
    14821 ttttctgtct ttgcctcagt cccctactga tgggccagaa tcaaaacaaa attcaggaag
    14881 caatggcaaa ctatgactac gagactgccg ttgaactgat aaacaaggaa cctcccacca
    14941 tcccactgtt gatgcagaaa gcaaaagccc tgaaaggaat cggcagcaat gcggaagctc
    15001 tacgttccat ccgccaagtg atagcggaag actccaccaa ccaacaggca cacatcgaag
    15061 cagcggaatg ctgtaaagca atggccaagt acaacgatgc gctggactac taccggaaag
    15121 ccatcagcct gaatcccaaa aacaagtatg cccgtttgca attcatcaac ctgctttgca
    15181 acaccaaaaa ctatgctgag gcttttggag aaagttcaat gatgtccgaa acggacagtt
    15241 cggccgtagt gcttcaccta caggctcaaa gccttgaagg gatgcaacag atactaccgg
    15301 ctatcggttg ctatgaagtc attcaggata aatatccgga cgattatctg gctgcggcca
    15361 aactcggaaa cctgaacatt gtggctggat atcccgaata tgccatccaa gctaccgaac
    15421 gttataggga acgggactcc accaacctga ttgtcaacca gcaaaacgct ctcgcctact
    15481 gccacgccga acaatatccg acagccatca aacgctatga aaagctgtgc caacaggggg
    15541 acagcagtac gcagacctta tactacctgg gagtcagcta ttacgcggat gaatattatt
    15601 acgaagcgca cgcgtgtttc agcaaactgc aaaaagagat ggaagaaaat cccaatctgc
    15661 tctattatct gggacgttgc tgcgccaaga cttcctggaa aaaagaaggc atcgaacacc
    15721 tggagaaagc tatcgaactg accattccca aagacagcac tatgatccga ctttacaaag
    15781 gcttggtgga ttgttgtaaa ctggctcagg atactccaaa gcaaatccag gctctcagag
    15841 aactgtacaa atatgacaag acgaaccata aacttcttta tgacatcgcc tggaactatt
    15901 catatcaact caaagacaac aaatcggccg aacgttatct gcaggctttc ttaaaaaccc
    15961 gaaaggcgaa tgccaggaaa gaagaaccgg tgagtgagaa aggagaactt gtactcggac
    16021 ttgaaaatta ttacaacgct gccgaaaatt ggctgaaaga cttacagaaa gaaaagttct
    16081 tcaaagaagg aataccgtta gaaagtcaga aacaatagaa tctatcccct catgaaacat
    16141 tggatactcc tcctctatct gggcttcagc gtaatgctgc gagcccagaa caccgcctcc
    16201 gttcaagaag caatggcaaa ctatgactat aaaacggtga tcagactgat tgatgaagaa
    16261 agtgcatcac cacagttact catacagaaa gccaaagctt taaaaggttt agggcgtacc
    16321 gccgaagccc tgtccacttt gcaacatatc attatcgagc tacccgaaaa tcagcaggca
    16381 ttggtagagg cagcagaatg ttgcaggcaa ttgagcaaat ttaacgaggc cttggggtat
    16441 tatcggaagg tgatggaact caatcccgaa catatttacg cacacttgca atacacccgc
    16501 ttgttataca actatcagcg atacggcgat gcattgcgtg agagtatcgc attggccagg
    16561 aaagacagtt ccgccaccgt attgcgactg atggcggaaa gcatggaagg agccggcatg
    16621 ccggtagaaa gtatgttttg ctatctttcc atcatcagga aatatccctc cgactatctc
    16681 tcggtagcta agctgggcag tatcttcaat acaatgaaag attacgaagg ggcaattgcc
    16741 ctgacagaag cataccgccg gacggacagc accaatgtag aagtgaaccg tcaaaacgca
    16801 ctggcgtatt gtctgcgcaa agaatatccc accgccatca aacgttatca ggatctgacc
    16861 gcccggggag acagcacact gctgacatgt tattatctgg gagtcagcta ctacgctacg
    16921 aaagaatact ataaagcgcg cgattggctg ctcaaagcaa aatcatgcca gtcacccggc
    16981 gccaacctac tctactattt gggacgttcg tgctccaaga cattatggaa acaagaggga
    17041 ataggatatc tgaaccaggc tatcgccctg actatccccg ccgacagtat catggagcgc
    17101 ttatactcag gcttggcaga ctgctacagg caaaccaagc aaacccggga ccaaatcaag
    17161 gctaccaaag aacaatacaa atatgcccct gacaagcata ttttacttta taacttggcg
    17221 ttcttatcgg acaaaatagg agatactaaa gccacagagc attacttgca ggcttttctg
    17281 cgaacaaaat ccaaacaaaa tgcagtacta cagcagccgg atgatgacga agaagaaccc
    17341 gcaccctaca tagattacta caaaagtgcc accaataaat tggaaagcat ccgaaaagag
    17401 aaattcttaa agggagaaaa gtgaattgat cggatagatg catcgtttcg gacaattcac
    17461 cactgagtgc agacagagtt tcacagaggg agaataatgg aaaataaatt tgaagatgtg
    17521 cggtagaagg tacagtagca cgtaaccgaa gtcacatcgg cacgcagccg aaattactgt
    17581 gctgcgtagc cgaagttacg gtgctgcgta gccaaagtta cggtgctgcg tagataaagt
    17641 tacggtgcta cgtagccgaa gttacggtgc tgcgtagata aagttacggt gctgtgtagc
    17701 cgaagttacg gtgctgcgta gccgaagcta tgacggcatc tccttttccg gacgtcacgt
    17761 tcacctgatt gcatcgaaaa gtgctcctta tcggttgagc cccatcccgg agaattctcc
    17821 aatgaaaacg tttgcataaa tagatggcac acagtaagaa agaaaacgga aaacaatccg
    17881 atgatttacc ctatattagc aacattaaat aataacgagc taatatcatg aaaaaattat
    17941 tgttactctt aggttcattc ctactgtcat taaccactta tgcagccatg aacatatcca
    18001 aaatcgatcc gcccttctgg ttcaccggta tgaacaatcc ggaactccag ttaatggtat
    18061 acggtgaagg catcggccag gcatccgtat cagtaaatta tcccggtgta tcgctcagca
    18121 gcgtcgtgaa actggaaagc aacaattacc tgcttgtcta cctgcatctc gataaagaag
    18181 taaagccggg caagatgccc atcacattta cggtcggaaa gaagaaattg gtgaaagagt
    18241 acgaattgaa agcacgcagc aaagccggag tcgatcacaa aggttttgac gcatcggatg
    18301 cattatacct gctgatgccg gaccgttttg ccaatggcaa tccggataac gaccggatag
    18361 aagacatggc cgaatataaa gtggaccgca acgacccgaa cgcacgtcac ggaggcgacc
    18421 tggccggtat cgaacaaaat ctggactatt ttaccgactt gggagtgacc gcactctggt
    18481 tcaccccggt actcgaaaat aatatgaaag gcggctcata tcacggatat gcaacaaccg
    18541 attattacaa ggtagaccca cgtttcggca ctaacgagga atatcgctca ttgatagcga
    18601 aagcccacaa ccggggcatt aaggtcgtga tggacatgat cttcaatcat tgcggagtag
    18661 aacatccctg gatcaaggac atgccttcaa aggactggtt caaccatgcg gacttcaaga
    18721 acaactttgt gcaaacttcc tacaagctga ctccacatgt agatccgtat gcctcggagt
    18781 acgatttcga ccagatgaac aacggctggt tcgtggaagc catgcctgac ctcaaccaaa
    18841 agaaccctca cgtatacaaa tacctcttgc agaacagcct gtggtggatt gagtacgccg
    18901 atatcgacgg catccggatg gacacctacc cgtatgccga ttacgatgcc atgagcaact
    18961 ggatgaaaga actgaacgaa gaatacccca actacaacac ggtgggcgaa acctgggtta
    19021 ccgaaccggc ctatacagcc tggtggcaga aagactccaa actctccgcc ccgcgcaaca
    19081 gtcacttgaa aacagtcatg gatttcagct tcttcgacaa agtcaacacg gccaagaatg
    19141 aacaaacgga cacttggttc aaaggattgg accgtgtcta caacaatttt gtatacgatt
    19201 atctgtatcc caatccggct tccgtactgg ctttcatcga gaatcatgac accgaccgtt
    19261 tcttgggtga aggcgaaaac ctcgatatgc tgaaacaggc ctccaccctt ttattgacca
    19321 cccgacgcat cccgcaactc tattatggaa cggaggtgat gatgaacgga gtaaagagta
    19381 aaagcgacgg ctatgtacga aaggacttcc cgggcggatg gacggacgat aaagagaatg
    19441 ccctgactcc cgagggacgt acccgattgc agaatgaaag ctataacttc taccgcaacc
    19501 tgctgaactg gcgtaagggc aacgatgtga tcgccaaagg cagcatgaaa cagttcatgg
    19561 tgcagcacgg cgtatatgct tatgcacgcc aatataaagg gaaaacggta ttcgtcctgt
    19621 tgaacggtac ggataaagag gtgaaacttc ccctgaaata ctatgccgaa gtgctgaaag
    19681 acaagactca aggaaaagac gtcattagcg gaaaagtaac ggcactcaat gaagaactga
    19741 caatggcacc ccgccaatcg atggttatag agctttaatc tcacaccggt tataaccgca
    19801 taagcaaagg gcacaaagga tttcacccga catcctctgt gccctttgtg tagcctaatg
    19861 cgaataataa tagtcaaaca tttgactatt atcggagaat attcctacct ttgcagcgac
    19921 taaaagaata cgacgatgac aaacaacgaa tcggagcgcg agctcgtcct acaaacctta
    19981 cgaacctgga tggcattccg ccaggccgtt cagcgggtac tcaaacgtca caacgtggat
    20041 atgaccttcg agatgctgca agtaatgaac tgcctgtgga acaaacaagg catcagccag
    20101 caatccctgg ctgagaaaac agcaaaggac aaggcttgcc tgactaatct gattaataat
    20161 ctggaaaaga aaaactgggt gatacggaaa gaaggcccct ccgaccgccg aaaccgcctg
    20221 attttcctga cgccccaagg cgaagaactt gccctcaccg tgaaacccct gatcaacgat
    20281 atctatgccc aaaccggaac agagatggag gcaagccgga taacggaatg catcgaagac
    20341 ctgaagagac tgcatgaagt gctcaatgag atctaaaaga aatccgccat gtccacccat
    20401 cagataaagc taaaacaatt gagaagactg aagttcagga acatctttct caacacagta
    20461 tgcatcctgc tggcattggc aggtatttca tggacagtaa actacttctg gaaatacgcc
    20521 cgctacgaga taaccaatga tgccgtagtg gatcaataca tcgctccgct aaacatccgg
    20581 ataccgggct atatcaaaga agtacgtttt accgaacacc agtatgttca tgccggcgac
    20641 acgttactga tactggacga ccgggaatac cggatccggc tgaaagacgc ggaagcggcc
    20701 ttgatggatg ccttgggatc aaaggaagtg ttaaactccg gcatccggac ttcaggagta
    20761 aatgtagccg tacaagaagc caacatagcc gaaacactgg cacgcctttc acagcaagaa
    20821 gcggaactga accgatatac ccggctcctg aaaaagcagg ccgtcagcca acaggattat
    20881 gaactggcca aagcgaactt cgaagcgacc cgggcaagat acaacgccct gttgcgacaa
    20941 aaagaagcgg cccaatcaca gtattccgaa accagcaaac gcagtacagg cgccgaagcc
    21001 aatatcctcc ggaaggaggc cgacctggag atggccagac taaacctgtc gtataccgtt
    21061 gtcaccgcac cctatgacgg atacacggga cgacgtacac ttgaaccggg acagttcgta
    21121 caaggcggac aaactctttc ctacctggta cggggcaatg acaagtgggt gacagccaat
    21181 tataaagaga ctcaaatagc ccatatctat atcgggcaaa aaatccgcat caaagtagat
    21241 gctttcagcg gacgcacttt tcacgggacc gtaaccgcca tttccgaagc caccggatcg
    21301 aaatactccc tggtaccgac cgacaattcg gcagggaact tcgtcaaagt gcagcaacgc
    21361 attccggtcc gcatcgatct caatgacgcc tcacccgaag agatggaatg tctccgtgca
    21421 gggatgatgg tagaaacgga agcggtccgc ccttaggctt atggtgaagc tcaatctgcc
    21481 tacccgtccc tgggtgcctc aatggttggg catcgtgacc atgtttattg tcatctttcc
    21541 catcaccctg ctcaacggtg cctacacagg aagtatggtc gaagtatcga acacgctggg
    21601 agtattgagc gaagatatta ccatggctta ctattcagct tcggtaggga tggctgttgc
    21661 ctatcccatc gtaccgaaaa tacgcaccat agccactccg aaaaccttac tgcttaccga
    21721 cctgctgcta cagatattct tcagcctggt atgcgcccaa accggtagta tggacgtcat
    21781 catggtatgc agtttctgta tgggatttct caaagccttc gtcatgttgg agttcatcat
    21841 cctgatccgc ccgctcttca gtccgaaaaa cgtacgaagt gaattctatg cctacttcta
    21901 ccccatcgtt ttctccggag gtcagctatc gatggctatc accgctcaac tggcctatca
    21961 ctaccaatgg cagcacatgt actattttgt caccatcctc ttgctgatcg cccttctgtt
    22021 cgtcatctgt ttcttccgct atgcaaggcg tcccatgcac attccgttca aagaaatgga
    22081 cggaagaagc atgttcatca tcgccaccgc tttcctgcta acgctctata catttaccta
    22141 cgggaaaaca ctcgattggt tcgcatcccc gaagatcaga gtatatgtat tcgtcatccc
    22201 gctcctgata gttctcttca tccatcggca gcgtacacaa ggcaaaccct ttgtcagcct
    22261 gaaaccactc tttctgcata aatccatcat cggatatggc ttcatggtac tcgccatgtt
    22321 cctgacagcc accagttcac tggtaaccaa ctatatgaac agcatcatcc gggtagacag
    22381 catacacgcc aattcgctga gcctgtggct attgcccgga tatgtggtag gagccgtcat
    22441 ttgcttctgg tggttccgat ggcaacgatg gaggtttcgc ttcctcattt caggaggtat
    22501 gttctgctac gtcatctatc tggctatcct ctactttggt atcacccctt atggaactta
    22561 tgaaatgctc tacctcccta tcctgttccg gggagtgggg atgatggtca tattcattgc
    22621 gttcggtgtg tttgttgtcg aagatttaga cccgcgcctg acgttgtcca atgccttctt
    22681 cctgatttca ttccgctcag tattggctcc ggtcctgtcc gcttcgttct ttaacaacat
    22741 gctttactat ctgcaggcaa aggggatgaa cattctttcg gaaaacatga cgctgaccaa
    22801 tccgctggcc gaacaaaaat acaatcaggc attgagcaat gccctggcgc aagggcacga
    22861 attcggcgag gccggacaat tggcagccaa cagcctgtac tccactttgc agcagcaatc
    22921 cctgctgctt gccctgaaaa ccctgatcgg ctatgtactg atactggcac tggtgattgc
    22981 tgtcatcgca gcgttcattc ctttccataa aacgctgaag gtggctgtag tgaagacggg
    23041 tgacgatatg gtataatgag aagggataca aaaaagccac ccaattgctt gagtggcttc
    23101 ttaaaatata aattaaatca agtaaaactt ttaaatacta gatttggaat ttattcagct
    23161 aacttgttgt cagaacccag cacgttgata attttgtgct tgtagagttt ttccatattg
    23221 tcgcgagccg gtcccagata tttacgcggg tcgaactcag ccggtttttc tgcgaatacc
    23281 ttacggatag cagcagtcat agccaggcga gagtctgagt cgatgttgat tttgcaaaca
    23341 gcagacttag cggctttacg cagttcctct tcaggaatac cgatagcagc tttcagtgca
    23401 ccaccaaact ggttgatagt tgcaacctct tcttcaggaa ctgaagatga tccgtgaaga
    23461 acgataggga atcccggaag ttctttcatt acaccgtcca atacgtcaaa tgccaacgga
    23521 ggaggaacca tacggcctgt cttcggatcg atgtggcact gttccggagt aaatttgtaa
    23581 gcaccgtgag aagtaccgat agagatagcc aatgaatcgc aacctgtctt ggtaacgaaa
    23641 tcaactactt cgtccggttc agtatatgtg tggtggtcag aagaaacttc gtcttctaca
    23701 cctgccaata cgccaagttc accttctaca gttacatcga actggtgagc gtattcaaca
    23761 actttcttag tcagagcaac gttttcgtcg taaggaaggt gagaaccgtc gatcattaca
    23821 gaagagaagc ctgagtcgat acagcttttg caagtttcga aagtatctcc gtggtcgagg
    23881 tgcaaaacga tttcaggatt tttgcagccg agttcttttg catattctac agcaccctga
    23941 gccatgtaac gcaacaatgt agcgttagca tactgacgag caccttttga tacctgcaaa
    24001 ataaccggag acttagtttc tacagcagcc ttgatgatag cctgcatctg ttccatattg
    24061 ttgaagttga atgcagggat tgcatatcca cccttgatag ccttagcaaa catatctcta
    24121 gtgtttacca gacctaaatc tttgtaatta accattttgt ttaaaagttt attgttagtg
    24181 aattaaaaat tctatgcaaa agtaagaata atcctttgaa tagagaaacc ctcgggcgga
    24241 aatatccgtt tgaggagcgt aattcaattc tatttcaaat tatttcccat cctttaagag
    24301 ctgtttgtaa tgtctacgta gcaaataaag gttttttatt gtttcctcat atatataatg
    24361 gtaggcaaat gatcgctgta accatccaac cacactctgc caccatatgt acgcaggggt
    24421 gcacccttat atttaccatc ctgctgaaac aggtaatcgc gcatgaaaac ttcattgtga
    24481 tcatatttca atccttttgt tgcttgaagc agagtgggtg aaaggatgat ctgatcgaac
    24541 agattccatt tgcctcgata gagcaaagtg cccactccct tatcttccag cgtcacccac
    24601 caggggttgt aaaggtcatc ttcagtcata tcctcgacg
//
