LOCUS       gnlProkkaOEPCOFIK_40   11795 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEPCOFIK_40.
ACCESSION   gnlProkkaOEPCOFIK_40
VERSION     gnlProkkaOEPCOFIK_40
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 13:30:13
            Original ID  :: gnl|Prokka|OEPCOFIK_40
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11795
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11795
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2481:6795]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2482..6795
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11795
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11795
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..1259
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 71.8;
                     E-value: 6.7e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg40_1"
                     /transl_table=11
                     /translation="MNRFTNKLEIRGAVYRPGIYQLSGKLNTIRELVHEAQGLTGDAFL
                     NRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLALMKNDILYIPSIHDLEDRGNVTVHGE
                     VAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDISRRIKNPRSTADNDTIGQMYTFS
                     LKDGFVIDGQPGFILEPYDQVYVRRSPGYQAQQNVAIEGEILFGGNYAMTSREERLSDL
                     VNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLGEAMIDSLGIRVEDTFTV
                     GIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLN
                     QAGGYSDNAKKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPSKAKKKGNIANILGYA
                     TSFSSLGMMIASIANLIKK"
     CDS             1270..2418
                     /locus_tag="ctg40_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             2482..3201
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.4e-17, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3222..4523
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.9e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.2e-121, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.5e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             4540..5664
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.4;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-21, bitscore:
                     65.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIARGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5674..6795
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 1.6e-33.
                     Score: 107.9. Matches aSDomain:
                     nrpspksdomains_ctg40_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 75.5; E-value:
                     6.4e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-30, bitscore:
                     96.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLLVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKVSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5764..6771
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg40_6_Aminotran_5.1"
                     /evalue="1.60E-33"
                     /label="ctg40_6_Aminotran_5.1"
                     /locus_tag="ctg40_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="107.9"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLLVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKVSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6792..6935
                     /locus_tag="ctg40_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             7138..8622
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8576..9835
                     /locus_tag="ctg40_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9844..10593
                     /locus_tag="ctg40_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             10593..11633
                     /locus_tag="ctg40_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 tccttaaccg cttcacaaac aaactggaaa tccgtggcgc tgtctatcgt cccggtatct
       61 accagctcag cggtaaactg aacacgatcc gcgaacttgt ccatgaagct cagggtctga
      121 ccggtgacgc tttcctgaat cgtgccgtcc tctatcgcca gcgtgaagac ctgaccagtg
      181 aagttgttca gatagacatt aagtctatca tggacggcac ttccccaaac cttgccctaa
      241 tgaagaatga catcctctac attccaagta tccatgacct ggaagaccgg ggtaatgtca
      301 cagttcacgg tgaggttgcc caccctgatt cctatcctta tgcggataac atgacacttg
      361 aggatctgat cattcaggcc ggtggcttga aagaagccgc ctctactgtc cgtattgata
      421 tatcgagacg aatcaagaat cctcgtagta ctgcggataa tgatacgatt ggtcagatgt
      481 ataccttctc tttaaaggat ggttttgtaa tagatggtca gcccggtttt atccttgagc
      541 cttatgatca ggtttatgtc cgtcgcagtc cgggctatca ggcacaacag aatgtagcca
      601 ttgaaggtga aatccttttc ggaggaaatt acgccatgac cagccgtgag gaacgtcttt
      661 ccgatttagt gaataaagcc ggcggtccga ccaattatgc ctatctgcgt ggtgcgaaac
      721 tgacccgtgt ggctaacgct agtgaaaaga aacgtatggg tgatgtaatt cgccttatga
      781 gcaggcaatt gggcgaagcc atgattgact ctttgggtat tcgtgttgaa gatactttta
      841 cggttggaat agatttggaa aaagccttga gcaatcctaa aagtaatgcc gatcttgtct
      901 tacgtgaagg tgatgtgatc tccataccta agaatactaa tactgtaact atcaatggtg
      961 ctgtcatggt tccgaatacg gtttcttata tgaagggaaa gaatgtggat tattacctga
     1021 atcaggccgg tggctattct gataacgcaa agaagagtaa gaagttcatt gtttacatga
     1081 atggtcaggt gacgaaggtt aagggtagtg gtaagaaaca gattgaaccg gggtgtgaga
     1141 ttattgtgcc tagtaaggct aagaagaaag ggaacatagc taatatttta ggttatgcta
     1201 cttccttcag ttctttggga atgatgattg cttctattgc taatttgata aagaaataaa
     1261 tgacctatta tgattgaaaa gcaatcttat caagaaccgt tttctgaagt ggataaaagg
     1321 aaagatgatg aaatggaaat agacttgatg gctatttttt ataagattat tactgttcgt
     1381 ggagtactat gcaaagctgc tggagtggga gtaataattg ctatagtggt ggcattgagc
     1441 attcccaagc aatatacagt aaaggttacc ctttctcctg aaatgggtaa tgcgaaggga
     1501 agtaatggtt tagccggact tgctgcctcg tttttgggag atggggctct aataggggaa
     1561 agcacagatg ccttgaacgc ttctctttca gcagatattg tttcttcaac tcctttttta
     1621 ttggaacttt tagaaatgga agtctccgtt tctaaaaagg atgataaaat gactttgggg
     1681 tcttatctcg atgaagagtc atctccttgg tgggattatc ttataggttt tccgggcata
     1741 gtaataggag gagttaaatc attattcgga gaagatacgg ttcctgccag tggagggcgg
     1801 caaggaacta tcgaattgac gaaagaagta aatgagaaga ttaattttct taaaaagaag
     1861 attagtgcat ccattgataa gaaaaccgcc ataacgagca ttacggtcac cttacaaaat
     1921 ccgcagatca ctgcggttat agcagattct gtcgttcata aattacagga atatattatt
     1981 gggtatcgaa cttcaaaagt aaaagaagac tgtgcgtatt tggaacggtt gtttaaagaa
     2041 cgtcagcagg aatattatgc tgctcaaaga aaatatgcgg attatgtaga cgcccatgat
     2101 aatgtggttc ttcaaagtgt acgtgctgag caggagcgtt tacagaacga catgagtttg
     2161 gcttatcaga tatatagtca ggttgctaat cagttgcagg tatccagagc caaagtacag
     2221 gaggaaaagc cagtctttgc agtagttgag cctgccgttg tacctttgaa accttcaggt
     2281 atgggactca aaatttatat tttattattt gtgttcctgt ccgtatctgg tactctcgtg
     2341 tgggtgcttt ttggcaaaag tctgctggct agcttgagaa aagaactgaa aaataaggag
     2401 atagaacagg ataaatgatg ctaaaacgtc gtttacaaca ttcttatatc aattaaattc
     2461 acttactata ttattaaacg aatgatacgt acagctatga taatggctgc gggcatggga
     2521 acccgttttg gccaatatac agaattgata cctaaagggt tcgtcaaagt gggaggtatt
     2581 ccaatgatag ttcgttctat tgatactttg ttatcatgtg gcattgagcg aattgtaatc
     2641 ggtacaggat ataaacaaga agtttatgaa gaattgaaga cagactatcc tatgcttgaa
     2701 acctgtttta gtcctcgtta tgctgaaaca aatagtatgt atactttata taatacgcgg
     2761 gagattctgg gcaatgatga ttttttattg ttagagtcag atttgatttt tgagaaacaa
     2821 gcaataatga gcttattgga gtgtcctgcg gcagatgcaa tgctaatagc tccagtgaca
     2881 aagtttcaag atcagtatta tgtggaacat gatgataatt ttcgcctttc ttcatgttct
     2941 gtcaataaga ataaactaaa cgctaaaggc gaattggtcg gcatccataa actatccggt
     3001 tccttttaca aaataatgtg tgctgattat gcgagtattg ttgatgaaca acccaatttg
     3061 ggatatgagt atgaattact acgaatatct tgttctcaat ctcctgttta tgtgcataaa
     3121 gtagaagggc tgaaatggta tgaaatcgat gacatatcag atttggaata tgcagagaaa
     3181 tatattgttc cgtattgtta attaaaataa tatatcaaat tatgagtaag acagtttata
     3241 ttgggatgac tgcggatatt atgcatccag gacttatccg cattattaat gaggctacta
     3301 aatacggtga tgttataatt ggtcttctta cagataaagc tattgcggag cataaacgcc
     3361 ttccttatct gacctatgaa caacgaaaag aggtagttca gaatattaaa ggcgtatgta
     3421 aagttgttcc tcaagaagaa tggagctatg ttgagaatct caaacgcatt aaacctgact
     3481 atataattca tggtgacgac tggaaaaccg ggcctttacg tgaagaacgt gtgcgcgtat
     3541 ttgaagtgat gaatgaacag ggaggaaagg ttatcgaaat tccatatact ttgggaatta
     3601 attcatcttc tttggataaa gatattaagg ctataggtac aacccccgat gtacgtttaa
     3661 aatcacttcg tcgtttgata aatgccaaac ccgtagttcg tattttggaa gctcatgatg
     3721 gactatgtgg cttgataatt gaaaatcagg aaatattaaa aggggataag agggaagtat
     3781 ttgacggaat gtggtctagt agccttacgg attcaaccag taaaggtaaa cctgatattg
     3841 aggcggttga tttaactacc cgattgcaag atttgaataa tattctggag tgtactacta
     3901 aacctattat ttttgatgga gatacaggtg gtaaaattga acatttcgta tttacagtac
     3961 gcactttaga acgtcatgga atctcagcta taataattga agataaagtt ggattaaaaa
     4021 agaattcatt gtttggtacg gatgttattc aaactcaaga tacaatcgaa ggtttctgta
     4081 ataagatcaa agcaggaaag gcatctcaga ttactgatga ttttatgatt atcgctcgta
     4141 ttgagagcct tatagcggga aagccggtaa gtgatgcttt agagagagct tttgcatatg
     4201 tccaagcggg agcggacggt attatgatac atagcaaaaa taagtcgggt gaagatataa
     4261 aagaattttg tttggcgttt cgaaaacagt atgctcatgt acctatcgtg gttgtgccta
     4321 ctacatatga tcatatttat gagtctgaat tgtgtgattg gggtgtgaat ataattattt
     4381 atgctaatca tatgcttcgt gccgcttatc ctgctatgat gaatgtcgca aagacaatat
     4441 tagagaatga acgtgcttta gaggtgcgcg aactgtgtat gcccataaag gaaatattgg
     4501 aactgattcc gggtactaaa taaaaagagg aatatcatta tgttaagcgt agaaaaagtt
     4561 tatgaaacgt ttctgagtca tgacgttgat ttttttacag gagttccaga ctcattacta
     4621 aaaaatattt gtgcctatat cacagaccat acttcacgtg agaaacatat catagctgct
     4681 aatgaaggtg cggctgtagg aattgcttca ggttattata tggcatcagg taaggttcct
     4741 gtggtttata tgcaaaattc cggcttgggt aatactgtta atcctctgct gtctcttgca
     4801 gatgaacaag tatacagttt tccaatgctt ttgatgattg gctggcgtgg tgaaccggga
     4861 acaaaagatg aacctcagca taaaaaacag ggtgaggtaa ctttagattt gttgaaagca
     4921 atgcggattc cttatataat tcttgattca aatgagaatg atgcatttat tcagctccat
     4981 gatatcatac aatcagcaaa aactaagaat attcctcatg caataattat tcggaaagat
     5041 gtttttggca aatataaact tcaaaaagaa ttcggatgta attatccttt atctcgtgag
     5101 gatgctttgc aaatagttgt ggattatctg cctgaaaatt cagtggtcgt ttctactact
     5161 ggcaagcttt ctcgtgagtt atttgaatat cgagaaatga aagagcaagg tcatgaacat
     5221 gattttctca cggtaggctc tatgggacat agttcatcaa tctctttggg tattgctata
     5281 gcaaagcaag atagacctgt ttattgcttg gatggtgatg gagcatttat tatgcattta
     5341 ggggcaatta gtaacattgg cgatttatct cctaaaaact attatcatat tttgtttaac
     5401 aatggtgctc acgagtctgt aggaggacag cctactttag gatttagttt agatattccg
     5461 gctattgccc gggggagcgg atataagcat acttatactg tttgtacaaa agttgaaatt
     5521 gaagaagcaa tgaagcagct tccaaagtta tgtggtcctg ttttgttgga aataaaggtt
     5581 aagatagatt ctcgggagaa tttgggacgt cccacgacta ctcctataga gaataaggag
     5641 cattttatgg attttttaaa ataaatatat tcgatgaaaa tagaaagaaa aatattatta
     5701 aatcctgggc ctgccactac tactgacagt gtaaaaatgg cacaagttgt tccggatatt
     5761 tgtcctcgcg agaaagaatt cgcaggtatg atgaaacaac ttcgggacga tttggtcaga
     5821 gttgctcatg ggaatttgga aaaacataca gctgtattat tttgtggctc aggaactatc
     5881 aatattgata tatgtctaaa ttctcttctt cctgaagaca aaagggtgct tatagtgaat
     5941 aatggggcat atagtacccg tgctgtagaa gtgtgtcaat attatggttt gcctcatatt
     6001 aatttggaat tttctgttta tgaacgtcct gatttattgg tagtggaaaa tgtgttacaa
     6061 gaaaatcctg atatagctat ggtttatact actcatcacg agacgggtac aggaattctg
     6121 aaccctattc gcgagatggg cgctatagct cataaatatc aggctaaatt tgtcgtcgat
     6181 actacttctt ctttgggcat gattcctttt gatatagaga aagataatgt agatttttgt
     6241 atggcatctg ctcaaaaagg acttcaagcg atgacaggtc tttcttttat tataggcaat
     6301 gaggaacaga ttaaggtttc aaaaaaatat cccaagcgtt cttactattg taatctttat
     6361 ttgcagtatg agaattttga gagaacaggt gaaatgcatt ttactccacc ggtacaaact
     6421 atttacgcca ctcgtcaggc attaaatgaa tattttgaag tgggcgaaga agctaagttt
     6481 gcccgtcaca aaagagtttt tgaggctatt cattcaggta taaatgaaat tggtcttaaa
     6541 agtgtaataa agcgtgaatg gcagtcagga ctggttgtct cagttcaata cccagaagat
     6601 cccaactggg attttgagaa aatacatgat tattgttatg agcgtggatt tacgatttat
     6661 ccaggtaaga tatcaactga ggatactttt agaatctgtg ctttaggaga gatagaagta
     6721 gatgatattg agaacttctt taaagtacta aaagctgcat taaatcatta taacgtcaca
     6781 ttaccgatgt catgattgca gaaatattat tgaagattcg tcatttttat ttttcccttc
     6841 gtggtataca cttccatccg gaaagtgtta tttctggagt gcctattcgt agctttcgct
     6901 tagtaggcaa atatggcaat attaatttga ggtgatgcat taggagttct ttattcttat
     6961 aaaaaggcat cggtagttat aggagataat gtttgtgtag ggtaatttgc ttttagtggg
     7021 agagaccata ttagaattgc ggtaaggggc gaagaagata ataaccaatt agtgagaata
     7081 ttggaaaaat ataattgata tcggtaaatg tagttgtttt tatactgtat ttaagtaatg
     7141 gaaaatctaa agcagaaaac tgtatcagga ataatgtgga gcgctataga acgtttctct
     7201 ttacaaggag tacagtttat aattcaaata atattagctc gtttgttact accatcggat
     7261 tatggtatga tcgggatgtt agctattttt cttcaagtcg ctcaagtatt tatagatagc
     7321 ggttttacaa atgctttaat ccagaaaaaa gatagaactg aagaggattt tgccactgtc
     7381 ttttatttta atattcttgt cgcagtatta ttctatggta tattgttttt ttcggcttct
     7441 ttgattgcag acttttataa tatgccgact ttagttcttg taattcgttt tatagcattg
     7501 tcgttgataa taaatgcttt atcggctatt cacagaacga aattaattat ttctgtaaac
     7561 tttaaaactc aatctaaaat ttcattaggt gcagctttta tatcaggcgt gattggaata
     7621 tggatggctt atgtcggttg cggggtttgg gctttagttt ggcaaactct cttaaatagt
     7681 ataattttga caattttgtt ttactgttta gttcattgga aacctttaca tactttctcc
     7741 aaaagttctt ttgaaagatt attcaatttc ggatctaaat tattgatctc aagtcttatc
     7801 aatacagtat atcgtaatct gtataccatt gtaataggaa aaaagttttc tgttgtagag
     7861 cttggttact atacaagagc agaacaattt gctatttttc cttccaataa tttaaatgct
     7921 ttagtttcta gagtagcgta tcctatttta agttccattc aagatgatga taaatgttta
     7981 acaaacgcat atcgaaatta tatcagatta tcctcatata taatttttcc tttaatggta
     8041 ggtttacttg ttttggctaa tcctattatt agtctattgt taacagataa atggtctggg
     8101 gttgttattc ttttacagat attatgtttg gattggatgt ttgatcattt gagccaaatt
     8161 aatttgaatt tattatgggt taaaggaaga tctgatctgt cgttacgtct tgaaataata
     8221 aaaaagacga ttgctatatt cattcttttt gtgtcaattc catttgggct tgaggtgatg
     8281 tgttggggta gagttattta ctctctgata gcgacatatt tgaatacata ttatactaat
     8341 tctcttattg atttgacctt aaagttgcaa gttaaagatg tatttccaag tttaatactc
     8401 tctttcataa tgggggggat cgtttttata tgtatttctt tctttgaaac tgatatagta
     8461 aaaattgtga ttggatgtat tactgggatg tccttctata ttttactttc ttttcttttt
     8521 aagctagatt cttttttttg tattttaaca ttgatcatta aaactaaaaa catagatgaa
     8581 aatattaaaa aagatttttc aagtaatagt aaagataatt aaccattgtg tgccagttga
     8641 tagtagatca ttgtatttta ttcctcatcc taattgtaga acagataaat atgatattat
     8701 aaattattcg tcagataatg ttctcgttct gttaaattat ttgctaaaaa aagatagtgc
     8761 tgaatattat aaaatatatg ttgaaattta tgattcttct cgtatttcag aatatcaaga
     8821 atatatttat ggcataaatc ctaatattag gtgtactttt ttatgtgcat gtgttggacg
     8881 ttttttcttt aataaagtat cttttaagga tatgttgtat gccttttttt gtttttgtag
     8941 agcaagtaaa tgttttacag ctacttttta ttatgatttt tcatttaaaa aacgctctca
     9001 acagattatt tgtttggggt attatactcc attcaaagat gattatcata tgggagatca
     9061 ttcttatgat aaatttcgta atacaacatg taactcattt gattactcta ttgctacttc
     9121 ttgtttaagt gctagaataa tttcaataga ttgtggaatc tcatatgata aattcaaagt
     9181 cttaggattt cccagaaatg atttgttgat atcgaaaaat aattgcaatg ttattaaaag
     9241 agaaatttcg aaatttgcgg gatatgatgt aactaaatat atagtttata ctccaacttt
     9301 tcgtgattat gagactgtta ctgaaggtaa tttgcgttca atactcggat atgttgattg
     9361 tgatttgttg aagttatcga aaatactatt gaagtttaat gcggctttaa ttcttaaatt
     9421 acatcctttg cagaataaaa cagtcttaaa aaaagattta cccaaaggta tacttgtttt
     9481 tgaacaaaca tataaatatg gattgtatga tcttttgtca ttttcagatg gaatgattac
     9541 tgattatact tctacctatt ttgatttttt attggtaaat aagccagtca tatttaattt
     9601 ctacgatatt gaagaatatc gtagagtaag aggtttctca tttgagccaa tagaattttt
     9661 ttgtgcaggt gatattgttt acaattataa tgaattgata gatgctgtga tgggacttct
     9721 ggctgggaaa gatattcatg ctgaacatcg acgtcatatt tctttattga tgaatcaatt
     9781 tcaagatgat aattcaacaa agagaatatg tgacatattt ttaaatgaaa tataataaat
     9841 aaaatgaatt atgcatttgt ggtgcaggca cgtttaggtt ctacacgttt gcctggaaaa
     9901 atattgaaac ctttctatgg taatcaatcg attcttgact taatggttca taagctttct
     9961 gctatatcga atattccagt aattattgct acaacaaatt ctgttatcaa tgaacctatt
    10021 gaaaagaagg cacttgcatt aggggtaaag tgcttcagag gtgaggagaa tgatgtttta
    10081 aaacgattca ttgatgttgc tgaatatttt gatatacagg gtatattccg aatatgttct
    10141 gataatccat ttttagatgt acatgcggca aggcaattgg tcgaaatagc aatgaaatct
    10201 tgtaacgatt atataagttt tgatattgat ggtactccat caattaaaac tcatttcggt
    10261 ttttggggag aatttgtaac gcttgatgcg ctgaagcgag ttataggatt tactgatgat
    10321 ttattgtatc gtgaacatgt tactaattat atatatagtc atcctgaact ttttaatatt
    10381 caatggattt caggatctcc agtcgtgtca aaacatcata atattcgact cacgattgat
    10441 acgttagaag atttttctgt agcacagaga atatataggg atttacaaga aaaaagagtg
    10501 gaaatatcga tagaagtgat tgtagactat gttcgaagac atgcagaata cattcaactg
    10561 atgaaacaac aaataaaaaa aaattctaaa taatgaagaa tacttatatt attggtgaaa
    10621 tagggcagaa tcataatggt tctgttgact tggctaagtt gattattgaa ttaatctcac
    10681 gacctgtaca tgaggatgtt tttggtatgg atttcatgcc aatgaatgct gttaaaatga
    10741 ctaaaagaga tttatcagaa gaattggctg tttctcaaat gaatcaaata tatgacaatc
    10801 ctaattcttt tgggcgtact tatggtgaac atcgtgcttt tcttgagctt gatgatcaag
    10861 cgcattttga gatttataaa tatgctaagt cattaggatt agattttatc gagacgttat
    10921 gtgccaaagg atgtctgtct ttgcttaaac tgttcacacc ggataggcta aaagttgcta
    10981 gtcgtgattt gactaactta ccattgcttg aagcattagc agaaactcat attcctatta
    11041 tattatcgac aggaatggct ggtcaaagag aacttgacaa tgcattagat gtgataacga
    11101 gatatcatag taatatagct attctacatt gtgtatctca gtatccaact catccaaata
    11161 atttgaatct acgtacaata acatatttga agaagcatta caataagttt gagataggtt
    11221 tttctgatca tacaataggt atttctgctg ctacagctgc tgtagcgatg ggagcggaaa
    11281 ttatagaaaa gcatgtaaca attgatcggc atatgaaagg aacagaccag cttggctctt
    11341 taggtccaga tggggttaat cgtatgattc gagatattcg catagcagag tgttggcttg
    11401 gtactgaaga tctttatata gaaaaagggg tggagaagtc taagataaaa cttgaacgtt
    11461 ctattgccac tcgaaaatat attccagcag gtagtattat tcaagagtcg gacattcatt
    11521 tactgagtcc tggtgatggt tataaatgga tagataaaaa aaatgtaatt ggtcattttg
    11581 ctaaacaaga tatatcagcg aatgaaataa tatatcctga ttttattgaa tagatatatt
    11641 cctactgcaa cttgtattac ggtatagagt actgcctgct ataagctaag tagtgattaa
    11701 taaataaggg taaaatacta aaaaaatgaa agagataaag cttatactta cagatattga
    11761 tggcgtttgg actgatggcg gaatgtttta tgatc
//
