LOCUS       gnlProkkaGLHNCKEN_1    12349 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLHNCKEN_1.
ACCESSION   gnlProkkaGLHNCKEN_1
VERSION     gnlProkkaGLHNCKEN_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:43:06
            Original ID  :: gnl|Prokka|GLHNCKEN_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 94153
            Orig. end    :: 106502
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12349
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10354]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10354
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12349
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12349
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(362..1891)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_89"
                     /sec_met_domain="Polysacc_synt (E-value: 3.9e-10, bitscore:
                     32.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFRSGYFQLFINIFTNVIAFGTSLCVSFVLTPYLISNLGKDVYS
                     FFPLANNFVNYMSIVIIALNSMAARFISIEIFKSNNVKAQEYISSIFISNVFLSVFLLF
                     PAVLIVCSLETLLNIPNSSIPDVKLLFALIFLSMIVNTLSSVFGVSVFAKNRLDLKAYK
                     EIIQGLLKGLLLLVLFLIYPPSIIYLGIVAVGLSFTNFGIDFIFTRKLFPTYVISFSYF
                     RYNLVKEVLISGMWNSINSLGSILLLGMSLFLANILIGPDASGELSIVQTLSGFMCGII
                     VLIYSVFLPRMTEKYANESYEHLAKEVRFSQKILSYFATTPTLLIILFGNSFFSLWMPG
                     ENSDYLQCLSVISMIPLLVHGNMWTIYGLNMTLNKQKNPSITLILFGVLNIVLVYFDHI
                     LLKGNLISLISISSFINVVYYLFYIPLYSTRQLGIKKIYFYSHMIKTFIFCLVVVIFGM
                     IFKNSLYINSWGLFFFYNIIFGCLFLLLHVWFTLNRGEKEKLIVWVKKKIQ"
     CDS             complement(2209..3093)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 276.9; E-value:
                     3e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_90"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.6e-11, bitscore:
                     37.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG
                     IREILIISTPDDLPGFQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCL
                     VLGDNIFYGDGLTEMVQFAVNKADLENKATVFGYWVSDPERYGVAEFDRSGNVLSIEEK
                     PQKPKSNYAIVGLYFYPNKVVEVAKNIKPSSRGELEITTVNQRFLSNRELKVQLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIALRKGWISPEKMKALAQPMLKNQY
                     GQYLLKVIDDLFV"
     CDS             complement(3096..3488)
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MKNSLCNSVSSVVKKLLEYGEDGTPVYVNELTALNQELRNLCADL
                     LLQKGESPEEEAEILVTLFKGYDTMLFNFSSENEQVIQELLDRSMTVLEKLPASVLKCQ
                     LLLECFEQTGDEELIREAKKNIERVI"
     CDS             complement(3671..4189)
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="METTDSDKHWYVVLTRTNSERKVRDYFQLQEVDTFLPVQNRVIER
                     EGKRIERERLLLPRMVFVHISRQEMAAVRSTLNVYDFLRDRSTGAPTCIPDAQMADFRY
                     MLDYSQDQVILTGESIPKGTRVVVAKGDLQGLRGELVRYNNKYHILVRIDMFGSAMVTI
                     PASYVRKEK"
     CDS             4219..4359
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MTKDENLLKTGIFKKHALFSVIYKLSFMIIGYRKSIRTGFEYYPI
                     R"
     CDS             complement(4903..5538)
                     /NRPS_PKS="Domain: oMT (51-151). E-value: 1e-15. Score:
                     48.5. Matches aSDomain: nrpspksdomains_ctg1_94_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 101.8; E-value:
                     7.2e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_94"
                     /transl_table=11
                     /translation="MNKRGFVSKILQNFRKPEGFFGRMILWGMNTGHASLAQWGMSCLQ
                     WQPEWSVLDIGCGGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKYLGTRCFIEQ
                     GGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLICCEISDPANKAW
                     TGLVEGMEIHSCDELKAILSKSGFTDTTIFRTKKEELCLVSHRQTVRL"
     aSDomain        complement(5086..5385)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_94_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.00E-15"
                     /label="ctg1_94_oMT.1"
                     /locus_tag="ctg1_94"
                     /protein_end="151"
                     /protein_start="51"
                     /score="48.5"
                     /tool="antismash"
                     /translation="VLDIGCGGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKYL
                     GTRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLI"
     CDS             5844..7184
                     /locus_tag="ctg1_95"
                     /transl_table=11
                     /translation="MNNVQQVKTYSQRKISDFLFILWAGGAALLSYSLVYALRKPYTAA
                     GFDGLEAFGMDYKVVVTIAQILGYVLSKFIGIKLISELKRENRMKFILISIILAEASLI
                     LFGLLPAPYNIGAMFLNGLSLGCMWGIIFSFIEGRRMTDILASLLGVSMVISSGTAKSA
                     GLYVMGTLNISEFWMPALIGGVALPLLALLGYALNRLPQPTAEDIAMKSKRETLNGKQR
                     WELFKNFMPFLTLLFIANVVLTILRDIKEDFLVKIIDVSQYSSWMFAQVDSVVTLIILI
                     IFGLMVFVRSNLKALSILLGLIIASMVVMAVVSFGYEQLQLNAIAWLFTQSLCLYLAFL
                     TFQTIFFDRFIACFKIRGNVGFFIAMNDFLGYTGTVIVLAVKEFFSPDINWTAFYNLMA
                     GYVGIICFVAFVCSFIYLHQRYRRENYGKTGVFRKKEEEKEVPDFVY"
     CDS             7228..8739
                     /locus_tag="ctg1_96"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITERWDI
                     TTPVTVFAGPGNNGGDALAVARMLAEKEYKVEAYLFNPKGELSADCQTNKELVEMMDNV
                     KFSEVSTQFVPPALTMDHLVVDGLFGSGLNKPLSGGFAAVVKYINASPATVVAIDIPSG
                     LMGEENTFNVKANIIRAQLTLSLQLPKLAFLFAENSEFVGEWKLLDINLSREAIEETEN
                     NYALLEAEEIHALIKPRNTFSHKGNFGHALLIAGSYGMAGASILAARACMRSGVGLLTV
                     HAPIRNNDILQISVPEAIIESDASDTYFACPTDTDDYQAVGIGPGIGRSEETEAALLEQ
                     LSGCQTPLVLDADALNILANHRHALTTLPKGSILTPHPKELERMVGKCQNSYERLMKAC
                     ELARTAKVHIILKGAYSAIITPSGKCYFNSTGNPGMATAGSGDVLTGVVLALLAQGYPA
                     EEAAKIGTYVHGLAGDFARKKQGVISMTAGDIISNLPLAWRLVSE"
     CDS             8812..9867
                     /locus_tag="ctg1_97"
                     /transl_table=11
                     /translation="MKKLIILTGLLLSTSAYAQTEVTAGVTRGKDYGVTYALPKTAINI
                     EVKVNKVTYTPGEFSKYADRYLRLTDVSGEPQEYWELVSVKAKSVGIPDSEHTYFVKLK
                     DKTVAPLIELTEDGIVKSINVPLSPKKSAPMQPATTQKKKINPRDFLTEEILMAGSTAK
                     MAELVAKEIYNIRESKNALVRGQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKD
                     EKIFNIRLTPDKEMDNEVAFRFSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKK
                     VDGIAYNVPGKAQVTLTEGKKQWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTG
                     GLIKVDREEGE"
     CDS             complement(10001..10354)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_98"
                     /sec_met_domain="PF05402 (E-value: 1.5e-16, bitscore: 53.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.2e-09, bitscore:
                     29.7, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSVDIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(10361..11749)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97.1; E-value: 1.4e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_99"
                     /transl_table=11
                     /translation="MTEQLKNKLSDSKTLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACILMVLGCGLKYY
                     AISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNIPMPILLCLIMLCIGTIAFFIYTF
                     YDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWLIALLCVLFYSAVFPFIKYATDLM
                     VQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRIGKGATLMIIGAVMLIGVHTLFAL
                     PILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGVLALIVALMLKAEDKKKGYGLQEA
                     NIKK"
     CDS             complement(11920..12300)
                     /locus_tag="ctg1_100"
                     /transl_table=11
                     /translation="MYLLLVILMVIAAILMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWGLAAFMVVMSIATAYVVPTSSSKTQDVIMEQAQQEEQTNPYNLPVGTTA
                     PKTDAAAPVEAPATETPATPAN"
ORIGIN
        1 ctcttagttt cacaagaggt taaccaaacc aaatcgaaaa aaggggcaat atctttatga
       61 atataagggg catgaagatt atcaaagcaa attagaagtt taggtataga cagatccttt
      121 aaggcttcca tcgtttcagg taataataag tcagagccac aacaattcat aaataagtca
      181 taatgatctt tattatatct tagcagatta atcaggtcct catttgcctg acaaacagtc
      241 tcatattttg acggatttaa aactgtaata ttcacattat gatgcttcaa ttcatcaaat
      301 atatgaactc tttgccattg agtcatataa gtatcatctt ctttaaaaaa atagagtatc
      361 ttcattgtat tttctttttc acccaaacaa ttaacttttc cttctcccca cgatttaaag
      421 taaaccatac atgcaacaaa agaaacaaac aaccaaaaat aatattataa aaaaagaaaa
      481 gtccccaaga attaatatat aggctgtttt taaatatcat tccaaatatg accaccacca
      541 aacaaaaaat aaatgtttta atcatgtggg aataaaaata gattttcttt attcccaatt
      601 gtcttgttga atacaatgga atataaaata agtagtaaac aacatttatg aacgagctaa
      661 ttgatattaa ggaaattaaa tttcctttta atagaatatg atcaaaatag actagaacaa
      721 tattcagtac gccaaataag atcaaggtaa tggagggatt cttttgttta ttcaatgtca
      781 tattcagccc ataaatagtc cacatatttc cgtgcactaa taaaggaatc atagaaatga
      841 cagataaaca ttgcaaataa tccgaatttt ccccaggcat ccacaaagaa aaaaaactat
      901 ttccaaacag aataatcaga agagtcggtg ttgttgcaaa atagctcaat attttttgag
      961 agaatcgcac ttcttttgcc aaatgttcat agctttcatt tgcatacttt tccgtcattc
     1021 taggtaaaaa aacagaataa ataagaacaa ttataccaca cataaatcct gataaagttt
     1081 gaacaattga cagttctcca gaggcgtccg gaccaattaa tatattagct aaaaataaag
     1141 acattcctaa taatagaata gagcctagag aatttataga attccacata ccggaaatca
     1201 agacttcctt tactaaatta tatcggaaat aggagaaaga aatcacataa gtaggaaaca
     1261 actttctagt aaatatgaaa tctatcccaa aattagtaaa actcaatcct acagcaacta
     1321 tacccaaata gataattgaa ggaggataaa ttaaaaaaag aactaaaagc aaaaggcctt
     1381 tgagtaaacc ttgaataatt tctttatatg ctttgagatc aagtctattt ttagcaaata
     1441 ccgaaacacc aaaaacagaa cttagtgtat ttactatcat cgataaaaat attaaggcaa
     1501 aaagtaactt tacatctgga atagagctgt ttgggatatt caataaagtt tccaaagagc
     1561 aaacaatcaa aacagctgga aacagtaaaa atacggaaag aaacacatta gaaataaaaa
     1621 tagaagaaat atattcctga gcctttacat tattactttt gaatatttca atggaaataa
     1681 atcgggcagc catggaattc aaagcaataa taacaataga catataattt acaaaattat
     1741 tagctaatgg gaaaaacgaa tatacatcct ttcctaaatt gctaatcaga taaggtgtta
     1801 agacaaatga aacgcataaa gaagttccaa acgcaattac attagtaaat atattgataa
     1861 ataattgaaa atatccagat ctaaatttca tttctattca tctcgtattt gattactaat
     1921 tctcttctca acttttcaat atacctatta tttcatttct tattatattt tcgaaaaaca
     1981 cacttggtag catggtgtaa tttctataaa aacaactgat tgaaataatg aagaggatac
     2041 catcaaatat gtaatcttat ctattattac gatgtacaaa ttttctatga gccattatac
     2101 tttacaacaa caaaagtatt tacaaacatt acccataaat accaaaaatt aacgataata
     2161 aagggcttaa taactctgtt tgttatatat aaaaaacaaa caattttatt atacaaataa
     2221 atcatcaata actttcaata gatactgccc atattgattc ttaagcattg gctgtgccaa
     2281 tgctttcatc ttttctggcg aaatccaacc tttccttaga gcaattccct ccaaacatgc
     2341 aacttttaaa ccttgccgtt tctcaataac ttcaataaaa gtacttgctt cggataaaga
     2401 atcatgtgta cctgtatcaa gccaagcaaa tcctcgacct aacaattgca cttttagctc
     2461 tctatttgat agaaacctct gattgacagt tgttatttct agctctccac gagaagaggg
     2521 tttaatattc ttcgcaactt caaccacctt attaggatag aaatatagtc ctacaatggc
     2581 ataattagat ttaggtttct gaggcttctc ctctatgctg agaacattcc cgctcctatc
     2641 aaattccgct acaccataac gttcgggatc acttacccaa taaccaaaaa cggttgcttt
     2701 attttctaag tcagccttat tcacagcaaa ctgaaccatt tcggtcaaac catctccata
     2761 aaaaatatta tcacctaaaa ccaaacagac agaatcatcc cctataaatt tttctcctat
     2821 gataaaagct tgtgccaaac catcaggtga aggttgctct gcatactcaa acctcacccc
     2881 aaaatcagat ccgtcaccca ataaacgttg aaatcccggc aagtcatctg gagtagaaat
     2941 aatgagaatt tcccgtatac ctgccaacat tagtacagaa ataggataat aaatcatagg
     3001 tttatcaaag ataggaagca actgcttact cactccttta gttataggat ataaccgtgt
     3061 ccccgaccca cctgctaaaa caataccttt cattgtcaga taactctctc tatgtttttc
     3121 ttagcttctc ttatcagttc ctcatctccc gtctgctcaa agcactccag cagcaactga
     3181 catttcaata cagaggctgg tagtttttct aaaacagtca ttgaacgatc caataattct
     3241 tgaataacct gttcattctc agaggagaaa ttaaacagca tggtatcgta acctttgaac
     3301 aaagtaacaa gtatttccgc ctcttcttcg ggagattctc ctttctgaag aagaagatcg
     3361 gcacacaagt tacggagttc ttgatttaac gcagtaagtt cattcacata gacaggagta
     3421 ccgtcctcgc catactccaa gagtttcttc actacggagg acacagaatt acacagagaa
     3481 tttttcattt taaaaaggaa tgaattatga ttcgtcgatt cttttcggtt tttatttgta
     3541 tagaagagta ataatatcca atagaattgt atctaacgac gtaacggggc attacatata
     3601 ttgttatcac ccgttacata tattgttatc gccattacat ataatggtat tttctttaca
     3661 tatatacttt ttatttctct ttccggacgt agctagccgg aattgtaacc atagcgctac
     3721 cgaacatatc gatacgtact aaaatatgat atttattatt atagcggacc aattctcccc
     3781 gcaagccttg taaatcgccc ttggcaacta ctacacgagt acctttggga atggactctc
     3841 ctgtcaggat cacctgatcc tgggagtaat cgagcatata gcgaaaatca gccatttgcg
     3901 catcaggaat acaggtagga gccccggtgg aacgatcacg aaggaaatcg tatacattca
     3961 gtgtacttcg gacggcggcc atttcctgac gggagatatg aacgaaaacc atacggggca
     4021 acaaaaggcg ctcacgctca atgcgttttc cttcacgctc tatgacacgg ttttgtacag
     4081 gaagaaaggt atctacctcc tgcaattgaa aataatcccg aactttacgt tctgagttag
     4141 ttcgtgtcag tacgacatac caatgtttat cgctatctgt tgtctccaag actacgttcg
     4201 taagaaaaag tttcagtaat gactaaggat gaaaatttgt taaaaacagg aatattcaaa
     4261 aaacatgcct tattttcagt aatttacaaa ttaagtttta tgataatcgg gtacagaaaa
     4321 agtattcgca ccggatttga atactatccg atacgttgaa ttattttatt ttaaacatat
     4381 atcggacata aagaaaagta tatttgtccg cctatatatt tacgggtgca aaggtaaaac
     4441 cttcttttga gtctccaaaa cttttcacag gttattttca tcataggaag ttatatgact
     4501 gaatatcaaa gacataattt atctctttgc aaataaggaa agcagcaata tgcataatac
     4561 taatgtggct tataaaagaa tgtggaaata agtggagagg caggctatgg agagtcttaa
     4621 cggtaacttg ataaacagac aactacgcac atcttgaacg tacgagaaga attttacgac
     4681 agaatgcatc cagaatataa gcaattgatt atcaaacaat aatatcttaa taagagaact
     4741 gtaggaagtt aacattaaca gtacgttaat attaacttcg taattgcaag atattaattc
     4801 tttagagata cgaagttaat aagctattga caaggaggga aagcactttt acgggcatta
     4861 acattgttaa cgtattcgtt ggtaagagcg tcccggcatt ggttacaacc gcacagtttg
     4921 ccgatggctt accaggcaca gttcttcttt cttcgtccgg aatatggtcg tatcggtaaa
     4981 accacttttg gaaagaatcg ccttcagttc atcacaggaa tgaatctcca tcccttcaac
     5041 aagtcccgtc caagccttat tggcaggatc gcttatctca caacagataa gaaacgatcc
     5101 accaggcttt aacacacgcg ccacttccgt aaaagcatgc tgcaggttac cccagaagta
     5161 gacagtctcg aaagcagtga ccgcatcgaa cgcataatca ggatagggaa gtcggtggac
     5221 tcctccctgc tcgataaagc agcgtgtacc gagatacttt ttattttttt tacgcgcaaa
     5281 ggtgacactc tccggtgaaa tatctatgcc atacgctttc ccttgcgggc aacgttgcaa
     5341 tatctgtagc aaattggcac caccaccgca accgatgtcg agtacactcc attccggttg
     5401 ccattgcaaa catgacattc cccattgcgc caatgatgca tgtcctgtat tcatccccca
     5461 aagtatcatt cttccgaaaa aaccttcagg cttccggaaa ttctgtaaga tcttgcttac
     5521 aaagcctctc ttattcattt gtctgctgat ttaatatttc aggcaaaagt acagtttctg
     5581 cccaaacagg caatacccag aaatagggaa tttatttcct aaaatatatt tgcaggtatg
     5641 catctgcttc ccgttaaaat tatgacgaac agatgcccgg aggtgcgatg ctcttttcgt
     5701 ttccgtttca taaatattac ataaacatta caacataaca gattcattat caatatctat
     5761 taataataaa cattcatata ttcagtaaca ggtctgtaac actaccctcc tatttttgca
     5821 ccggaaaaca acaagcagat gttatgaaca atgtacagca agtaaaaact tattcgcaga
     5881 gaaaaatttc tgatttcctt ttcattcttt gggcaggcgg agcagcgctg ctctcctatt
     5941 cattggtata tgcactgaga aagccttaca cagcagccgg atttgacgga cttgaagcgt
     6001 ttggaatgga ctacaaagtg gtagttacca tcgcacaaat attaggatat gtactttcta
     6061 aattcatcgg aattaaatta atctccgaat taaaacgaga aaaccggatg aagtttattc
     6121 tgatctccat aattctggct gaagcttcgt taatattgtt cggactgttg cccgcacctt
     6181 ataatatagg agccatgttt ctgaacggac tttcactggg atgtatgtgg ggaatcattt
     6241 ttagctttat cgagggaaga cgaatgacgg acattcttgc cagcttactc ggagtcagta
     6301 tggtcatcag ctcgggtacc gccaagtcgg ccggtttgta tgtcatgggc actttgaaca
     6361 tcagcgaatt ctggatgcct gccctgatag gcggagttgc ccttcctcta cttgccttgt
     6421 tgggatatgc actcaaccgg cttccacagc caacagccga agacattgcc atgaaatcga
     6481 aacgggaaac actgaacggc aagcaacgat gggagctatt taagaatttc atgcctttcc
     6541 tcactctgct ctttatagcc aatgtggtac tgactatctt gagagatata aaggaggact
     6601 tcctggtaaa aattatcgat gtctctcaat actcttcgtg gatgtttgca caggtagaca
     6661 gcgtagtaac cctcattatt ctgataattt tcggattaat ggtgttcgtc agaagcaact
     6721 tgaaagcact gtcgatatta ctgggattga tcattgccag catggtagtg atggcagtcg
     6781 tttcgtttgg ttacgaacaa ttgcagctga acgccatcgc ctggctattc acccagagcc
     6841 tgtgtctcta tctggctttt ctcactttcc agactatctt cttcgaccgt tttatcgctt
     6901 gcttcaaaat tcgaggtaac gtgggtttct tcattgctat gaatgatttt ctgggctata
     6961 cgggaacagt catagtattg gctgtcaaag aattcttttc accggacatt aactggacag
     7021 ctttctacaa tctgatggca ggatatgtgg gaataatctg tttcgttgct tttgtatgct
     7081 ctttcatcta cctgcaccaa cgctaccgca gggagaatta cggaaagaca ggggtattca
     7141 gaaaaaaaga agaagaaaaa gaagttcccg atttcgtata ttaattgcta tctttgtggg
     7201 tcaaaaaact taaaatgaaa gttcaccatg aagatttttc caagtagcag catcaagaaa
     7261 ctggatgctt acaccataga acatgaaccg attgcatcga tcgacctgat ggagcgggct
     7321 gcacaggcac tgaccaaagc catcaccgaa cgctgggaca tcacaactcc cgtcacggta
     7381 tttgccggac cgggcaacaa tggcggagat gcccttgccg tagcccgaat gttggcggaa
     7441 aaggaataca aggtcgaagc ctatctgttt aacccgaaag gggaactgtc tgccgactgc
     7501 cagaccaaca aggagctggt agagatgatg gataatgtga agttcagcga agtaagcaca
     7561 cagtttgtac ctcctgccct gacgatggat catctggtag tggacggact ttttggttcg
     7621 ggacttaata agccgctaag tggcggtttt gcggcagtag tgaaatatat caatgcatcg
     7681 cctgccaccg tagtcgccat cgatatcccc tcgggactga tgggagaaga gaacacattt
     7741 aatgtaaaag ccaatatcat ccgtgcccaa ttgacattga gcctgcaatt gccgaaactg
     7801 gctttcctct ttgctgaaaa ttccgaattc gtaggcgaat ggaaactgtt ggatatcaac
     7861 ctcagtcgtg aagcgattga agagacggaa aacaattatg ccttattgga agcggaagaa
     7921 atacacgctc tgatcaaacc ccgtaacact ttctcacaca aaggaaactt tgggcatgct
     7981 ctgctgattg ccggttcgta cggcatggca ggcgcgtcga tactggcagc ccgcgcctgt
     8041 atgcgttctg gtgtaggctt actgacagtc catgcaccta tacgcaacaa tgatatcctg
     8101 cagatttcgg ttccggaggc aattatcgaa tcggatgcca gcgataccta ctttgcctgc
     8161 cctacagata cggatgacta tcaggctgta ggaatcggtc cgggcatcgg acgctcggaa
     8221 gagaccgaag ctgcactgct tgaacaactc agtggctgcc agacacctct ggtactggat
     8281 gccgatgcac taaacatatt ggccaaccac cgccacgcac tgaccacatt gcccaaaggc
     8341 tctattctga ctccccatcc caaagaactg gaacgcatgg tgggcaaatg ccagaactca
     8401 tacgaacgac tgatgaaggc ctgtgaactg gcccgaaccg ccaaagtaca tatcatatta
     8461 aaaggagcct attcggcaat tatcaccccc tcgggcaagt gctatttcaa ctctacgggt
     8521 aatccgggta tggcaacagc cggaagcgga gatgtattga caggtgtcgt gctggctttg
     8581 ctcgcacagg gatatccggc tgaagaagct gccaaaatcg gtacttatgt acatggtctg
     8641 gcaggtgatt tcgcacgcaa aaagcaaggc gttatcagca tgacggcagg agacattatc
     8701 agtaatctgc cattggcttg gcgtctggta agcgaataaa agttaacaac ttatgatttt
     8761 ccaaataact tcattaactt tgttttttaa accagttaaa ataaaccgga aatgaaaaag
     8821 ctaattatac tgacagggct gttactctct acctcggctt atgcccagac cgaagttaca
     8881 gcgggagtta cccggggaaa agattacggt gtaacctatg cacttcctaa aacagcaatc
     8941 aatattgaag tcaaagtcaa taaagtgaca tatactccgg gagaattcag caagtatgcc
     9001 gaccgttatc tccggttgac cgatgtgtcg ggtgagcctc aggaatattg ggaactggtc
     9061 agcgtcaaag caaaatctgt cggtatcccc gatagcgaac atacctattt tgtcaagctg
     9121 aaagataaaa cagtagctcc gttaatagaa ttgaccgaag atggtatcgt aaaatcaatc
     9181 aacgtaccgc tatctcctaa aaagtcggct ccgatgcaac ccgccacgac acagaaaaag
     9241 aagataaatc cacgtgattt tctgaccgaa gagattctga tggcaggttc tacagctaaa
     9301 atggcggagt tggttgccaa agagatttat aacattcgtg aaagtaaaaa tgccctggta
     9361 cgcggacagg cagacaacat gcccaaagat ggggagcaac tgaagattat gcttgccaac
     9421 ctggaagagc aagaggctgc catgaccgaa atgttctcgg gtaccttgaa taaagacgaa
     9481 aagatattca acatccgcct cactccggat aaggaaatgg acaacgaagt agccttccgc
     9541 ttttcgaaga agctgggcat agttgctaat aacgatcttg caggagagcc ggtttatatc
     9601 acgctgaaga atctgaaaac cgtcaacgta ccggaagacg atggcaaaaa gaaggtggac
     9661 ggcattgcct ataatgtgcc cggcaaagca caagtaacac taacggaggg gaaaaagcaa
     9721 tggtttaacg gagaacttcc tgtcacacaa ttcggtacca tcgaatatct ggctccggcg
     9781 cttttcaata agaaatcgac tgttcaggtt actttcaacc cggatacagg aggcttgatc
     9841 aaggtagata gagaagaagg agaataaaac ataatcaaaa actccggccg atcttaaatg
     9901 aagtgcaccc caaaagttca tgtttaactt ttagggtgca cttcattttt aaattagccg
     9961 gagtctcttt attatattcc aatagtatat cgtaatgcaa tcagttctca atcactaatt
    10021 tcacaaatcc gtctttctgc aactgagtga tataagccgt aatacgtgat tcgtaatttt
    10081 cttcataatt gaagtgttct gccagctctt caataatccg gcgtacggtt ctctttccat
    10141 caatcaactc ccatacggca gtgccatgat cttccagccg gacatgaata tccacagaca
    10201 ttcctttagg caacaagaat cgccgcatcc actcgtattt aaaccggggg aaagcaatgg
    10261 taacggtacc atcgcttccc ttttcggccg taatattttc actacggaaa ggaattacat
    10321 ccagaagatt tattttctct ttcacgtctg ccatatactg ttattttttg atatttgctt
    10381 cctgcagtcc gtatcccttc ttcttgtctt ccgctttcaa cattaaagct acaatcagag
    10441 ccaaaacacc gaaacaagca aagatagcca taggcaaagt atagtcataa gtctgcgctc
    10501 catccacaac aggacctttg caataggtat tcaacaccca tccgatcaac agaggtaccc
    10561 ccatcaatcc ccagttctgc acccagaaaa tcaaagcata ggcagtaccc agttgtttct
    10621 ccggaataat tttcggaaca gaaggccaca tggccgaagg caccagtgaa aaagcaatac
    10681 ccagaacaat cataatcaca gtggcaaacc accatacgtt cagaatggga agcgcaaaca
    10741 aagtatgcac accaatcagc atgacggcac cgataatcat caacgtcgct cccttaccga
    10801 tacggtcata aagagtacca aacaacggag tcaggaagat ggtacctatc ggtagtaatc
    10861 ccggaatatt tccggccagc ttagggtcta cgttatactt ctgcaccatc aagtcggttg
    10921 catatttaat aaaggggaaa acagcagaat agaatagtac acacaataaa gcaatcagcc
    10981 agaagccttt attggtgaca atcagcataa cgtccttcat acggaacggt tcttccggtt
    11041 cttctccctg agcatctaaa gaagcgtcaa gtttcttatc ataaaaggta taaatgaaaa
    11101 aggcgatagt accgatgcac agcatgatca ggcacaacaa aataggcatc ggaatattgg
    11161 tatggaaact gccgctttca tccgtatagc cgaaataatc ggcaatggga acggtaagca
    11221 ccatagccaa agtggtaccg atacgtgcgg ttgccatctc aagtcccata gccaaagcca
    11281 tctctttacc tttaaaccat ttcacgataa tcttagagac agtgataccg gcgatctcta
    11341 cgccgacacc aaagatagcg tatcctaaag ccgccagaaa gacctgagtc ttgaaaccca
    11401 taatcaaagc tccctcagga aaagtagtag agatagcata atattttagt ccacaaccca
    11461 acaccatcag tatacaagct cccataccgg tgaaacgaac tcccatctta tcgagaataa
    11521 taccaccgaa aatcaacatg agcaggaata cattgaacca tccgtaagca ctggtaaaga
    11581 atccgtagtc caaactatcc cagagaagct ctttctcgag cataggcttt aaaggggaca
    11641 ttacatcggt gaggaaatag ccgcaaagca tagtaaacgc gaccagagcg agcacactcc
    11701 aacgaagtgt tttggagtca ctcaatttgt ttttcaattg ttctgtcatt gtaatattta
    11761 aactcagaaa ttagtaaaag tgttattgcg aacaaaggta actaaatctg ccttgtatgc
    11821 ctaacaaaaa gatgcatttt acggcaaaaa ataagcgaag ctgcaagttt cggtttgaaa
    11881 ttgcagcttc gcttatcgtt tcttaaaaag aatctgttgt tagtttgccg gagtagccgg
    11941 agtttctgtg gcaggtgctt caaccggagc agcagcgtct gtcttcggtg cagtagtacc
    12001 tacgggcagg ttataagggt tggtctgctc ttcctgctgt gcctgttcca taatgacatc
    12061 ttgtgtttta gaagaagaag tcggaacgac atacgcagta gcaatgctca tcacaaccat
    12121 aaatgcagct aagccccaag ttgctttttc cagaaagtct gtagttttgc gtacacccat
    12181 aatctggtta gatgatgaga accctgaagc aagaccaccg ccttttgagt tctgaatcaa
    12241 cacaatgaag cacatcagta tggctgcaat aaccattaag ataactaata ataagtacat
    12301 tttgttattt tgatttagcg ttaataatca atttctccaa aaatctgat
//
