LOCUS       gnlProkkaCBGCMNJE_288  10386 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBGCMNJE_288.
ACCESSION   gnlProkkaCBGCMNJE_288
VERSION     gnlProkkaCBGCMNJE_288
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 17:39:59
            Original ID  :: gnl|Prokka|CBGCMNJE_288
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10386
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..66)
                     /locus_tag="ctg288_1"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIV"
     protocluster    1..10386
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7158:7506]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7159..7506
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10386
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10386
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(100..636)
                     /locus_tag="ctg288_2"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(678..2222)
                     /locus_tag="ctg288_3"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHILHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(2415..2639)
                     /locus_tag="ctg288_4"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             2912..3745
                     /locus_tag="ctg288_5"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             4211..5722
                     /locus_tag="ctg288_6"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             5796..6860
                     /locus_tag="ctg288_7"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             6882..7169
                     /locus_tag="ctg288_8"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNNYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(7159..7506)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg288_9"
                     /sec_met_domain="PF05402 (E-value: 1.2e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 4.3e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(7551..8939)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg288_10"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(9230..9625)
                     /locus_tag="ctg288_11"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEASATETPAPAAE"
     CDS             complement(9648..10385)
                     /locus_tag="ctg288_12"
                     /transl_table=11
                     /translation="MIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNLYILHDINF
                     GAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTLALIDAFLS
                     TAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEKSETDPVVY
                     LKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVKQQRYSKAL
                     EIIKKLSLKYPKKNAXXXXEIDY"
ORIGIN
        1 tacaatacgt tcgctctgtg ttccttttcc tgaacccgga gcaccgaaaa ttacaatgtt
       61 caacatcttt ttaacctaaa aattaatttg tatttgaatt taatctacta cagtataaat
      121 atcgggataa ttgcgtccga aaccatcata atccaatccg tagccaacga taaaatcatt
      181 cggtatttcc atcgctacgt attctatgtt cagattgacc ttcagctttt ccggtttcac
      241 cagcaaagag gcgatatgaa tcgcttcggg gttgcgtgtg cccagtgtat ccagcagacg
      301 ctgcatcgtc agtccggtat ctacaatatc ttctacgatc actaccgtac gtccggcaat
      361 gtcttcattc agcccgatca cttctttaat tactccggtg gaagtcaccc cctgataaga
      421 tgccaacttc acgaatgaaa tttcgcacgg aatcgtaata tgcttcagca agtcggcggt
      481 aaacatgaac gagccgttca acacactgag gaagagcgga ttcttacctg ccaaatcacg
      541 attgatttcg ttcgctacgc gaatcacttc tttttgaata tcctgttcct taatggaaac
      601 agtaaattgc ttgtctttta tctgtatggt atccataacc ggtcatttta aaaaagttgt
      661 cgcaaaaata caatttttta ttctaccccg tgcatcatct tctgtaattt cttcgagaga
      721 aggaacagaa tcagtgaggc aacaccggac ataatgacga acagcatgaa gaagtcgtac
      781 atggtagcga tctgataacc aaggattgat ttcacttttc cgtcttcggg atagaggccg
      841 ctcagcatac ctgcaaattt atttgcggtg gcggtagaaa gataccagat ccccatcatc
      901 aaggaggcga aacgtaacgg actcaactta ttaaccatag aaagcccgat aggtgacaga
      961 gcgatttctc ccattgtatg aataaagtaa agccctgtca gccagatcat gctcaccttt
     1021 actcctggaa tagcatcttt cactccaaaa cagatgaaga gataaccaag agaaagcagc
     1081 aacagaccga ttgcctgttt ggtaggggaa gccggttcca tgtttcgctt attcagaaag
     1141 ccccatatac cgggcataat ataggcaagg atcactacaa aaagcggatt gaatgactgg
     1201 aaccacgaag ccggcatctc ccagccgaaa atgctgcggt cagtctgttc ggaagcgaat
     1261 aatgtcagag aagctcctgc ctgctcgtaa gctgcccaga agaaaatgac gaagaaagct
     1321 acgatataga ttacgaaaat acggctacgt tctactttgg tcaatgaacc atccagcaga
     1381 atgagcactg gaaagacaat acaagccgta aagataccca cactaatcca gtcatcgcta
     1441 aaggcatagc taaaaaaggc tattaaggca accgtaaggg cagtaatgat gatgatatta
     1501 cgtactttgg tacgtttgtc catcttcgga tgtaaaatat gttcggcttt atcctccttt
     1561 ttttcacgtc tggcgtcggg gacgatacca atcggttcac cggaaggaga gaaaaggtat
     1621 ttattcttct gagtttcaaa gaggacaaca gtgaacagcg tcatgattcc ggatgcgagg
     1681 aatccccatt taaagtcctg cggattccct gtgtctccca agaaaccgca aatcaaagga
     1741 gcggcgaaag aacctacatt aacacccata tagaaaatgg tgtatgcagc atccaaccgt
     1801 ttgtccccgg gttcatataa ttgcccgacg agcgaagaaa cggtaggctt aaagcaaccg
     1861 ttacctaaaa tcatgaatcc gagcccgcca tacatcagcc agtgggcaag gtctgtattg
     1921 ttcagtgaag aggcactcat aaacatcagg aactgaccga ctgccatcat caccgctccc
     1981 caaaataccg aacgacggat accccaatat ttatcggcaa tgtatccgcc gatcaacgga
     2041 gtcagataga ccagtccggt gtagctaccg tagatagagg ccgccgcttc tttatcaaaa
     2101 agcaatgcct gcgtcagaaa gaggataaag atagcacgca taccgtagta actgaaacgt
     2161 tctgccgtgc tcgttgcgaa aattaggtaa aggcctttcg ggtgcccttt caatgaactc
     2221 atgaattatg tgtttagtag tttatggggc gcaaaggtac taaaaagtag attaaatgcc
     2281 tcaaaaaaga agattcttat ggaatagaaa aatacaggat ggcgtgcaag aagtctcagt
     2341 tacccacctt attatgtttt caacagtgta aataatcaag tggatattct ccttaaatgt
     2401 gggtcagtcc ccatttatcc aaaggtaaat tcaacattct caatactggc atagagcatt
     2461 ccttcttttt ttctaagcag gattttgttt tcccttgcca gccaaccgat agcaatcgct
     2521 acatcctcga acgtcaaacc taactcatgg cacaaagtga acatagactg ttcgcccttt
     2581 tcatttaaga tgcgccatac tttcccggca tttgagccaa ttcttttctt ttccatcatg
     2641 caaactttag aagattaaac aatttatatt tataatctaa acattgtgag cacaggagaa
     2701 taacgtaaag cacattactg cactacaaag atatcatttt tttcgaaaaa agcaaataat
     2761 caaagcatta gctgctatta ttagttacat tctaatcatt tatgccgatc tctgctaaaa
     2821 aatagcacaa ataaagaaac agttcaattc tttttcataa gtttgcagac gagaactaaa
     2881 ctaatatcgc acatttaaaa ctttaattag catgactacc aaaaaactaa caggaatact
     2941 ttcgttattc ctttgtatta tttgcctcgt gagctgtaat gacaatgatg acaacttttc
     3001 tccaatcact ctggaatatg aagatcctca aattaagttc gacaacgaga gccgttctta
     3061 cacactgact ccgttcagca aagaaacgac accactcttc atcaagggtg gagacggaac
     3121 ttacaaagtg accaatgaga atgagaaagt ggtacaagta aactaccaca acggaagttt
     3181 aacattgaag gcaaaggaaa taggacgcgc atccatcaag atagaagaca gttcgaataa
     3241 tatgtatata ctgtctgtcg ttgtaaaata tcgtactctt actcataagg cgtttacagc
     3301 aaaagtcatt gtgaagggag acgagcttac atctgaagaa cacactgagt taatgaacaa
     3361 agtgggcaat tcatatccga ttaataaata tgtatttact tttatgaatg cggaagacag
     3421 caaaggaaca gtagatttgt attattcaga taataacatg aaaacaggca actttgaaaa
     3481 agaacatata gtgctggatg aagaaaatgc cattcccatc aaaggtgaat acaaattgag
     3541 tgagtattac cgtataacaa tcaaagaaga taatggcaaa gttattgata ctttctatat
     3601 taccaagaac tttctaccac tcctcaatac aagaatgaat gctcatccgt taattcagta
     3661 ctgttttgtc agagatttaa ccgcacagta caaacaagat taccttgcac tggaaaatgc
     3721 atatctgatt caaatagcag aatgagagct acactgattt tcttctttag cagagtgaat
     3781 agagtattta ttatatgagc aaactcccca ttagatttag caaaaaacaa taagctatta
     3841 gctaatcaag aatatgccca tagcatattt atcacaatca cctcttccac ccttttcctg
     3901 aacctttgat gaataaggcg attgcgggtg aaagaggtga accagaggaa tatacagtag
     3961 tagaaacacg catgggaagg ttaacaaaca gccatgaatg ttctccggag agagtaaaag
     4021 taaatgagat aacaatcatt aatatctgac ttctcaacta ttaataactg acacatcaac
     4081 tattaatacc tgacaactca agtattaata cctgaagttc cttcccaaaa agccgaaaac
     4141 caaccggaat aaaggattaa ttcagagttt ttgtgtaagt ttgtgcgtcg aaaactaaaa
     4201 gaatatcgca atgaaaatat ttccaagcag cagcattaag aagttagatg cctataccat
     4261 tgaacatgaa ccgattgcat ccatagattt aatggaacgt gccgcacagg cactgactaa
     4321 agccatcacc aacagatgga atccggaaac acctgtcacc atctttgccg gaccgggcaa
     4381 taatggcgga gacgccctcg ccatcgcccg catgatggcg gaaaaaggat acaagatcga
     4441 agtatatctc ttcaacacga aaggcgaact ttcgcccgac tgccagacca acaaagaact
     4501 ggtagagatg atggaagaag taactttcca tgaaatcagc acccagttcg tacctcccac
     4561 actgacaccg gaacatctcg tgatcgacgg attattcggt tccggactca acaaaccatt
     4621 gagcggagga ttcgctgccg ttgtgaaata tatcaatgcc tctcccgcca tggtagtctc
     4681 catcgacatc ccttccgggc tgatgggaga agaaaataca ttcaatgtaa aaagcaatat
     4741 tatccgtgcg gacgtcactt tcagcctgca acttcctaaa ctggccttcc tctttgccga
     4801 aaatacagaa tttgttggcg aatgggagtt attggacatc cagctgagcg aagaaggaat
     4861 cgaagagact gaaacaaact acgaaatgct ggaaatcgaa gaaatccgtt cactgatcaa
     4921 accacgccaa caattcgccc ataaaggaaa cttcggacat gccctgctga tagccggctc
     4981 aaaaggaatg gcaggtgcat cggtactggc cgcccgtgcc tgtttgcgat cgggagtagg
     5041 tctgctgacg gtacacgcgc cgttatgcaa caacgatatt ctgcaaacgt ccgcccccga
     5101 agccatggta gaaacagatg tcagcgaaac atgctttgcc gtacctaccg atacggacga
     5161 ttaccaagct gtcggcatcg gtccgggact cggtcgcaac gaagaaacgg aagccgccct
     5221 gatagaacaa ctggaacatt gtcagactcc gacggtactg gatgccgacg cactcaatat
     5281 tctggccaat caccggcata cgctcaccca tctgccgaaa ggttccatcc tcacccctca
     5341 cccgaaagag ctggaacgcc tggtcggcaa atgtcaggac tcatacgaac gactgatgaa
     5401 agcctgcgaa ctggcgcaca ctgccaaagt acatatcatt ctgaagggag cttattccgc
     5461 cattatcacc cccgaaggca aatgttactt caaccagacc ggtaatcccg gtatggcaac
     5521 aggaggcagc ggagatgtac tgacaggagt aatccttgca ctccttgcgc aaggctatcc
     5581 cgccgaagac gccgcaaaga tcggtactta cattcacgga ttggccggag acatcgccca
     5641 gaaaaaacag ggcatgatcg gattaatcgc aagtgatatc gtgacttgtc tgccgacggc
     5701 atggcgactt gtaagcgaat aaaagttaag aacttacggt ttattcaata acttcattaa
     5761 ctttgttttt caaaatcagc taaaaagaac cgaatatgaa aaagttaatc atagcaacag
     5821 gactactaat ggcaacttcc gcctatgcgc agaccgaagt gctgacagga gtgacgcgag
     5881 gaaaagacta cggagtagtg tacgccctcc ccaaaaccca gatagaaata gaaataaaag
     5941 caaacaaagt caactataag ccgggtgaat tcagcaaata cgccgaccgc tacctgagac
     6001 tgaccaacgt ctctgccgaa cccgaagaat actgggaact gaacagtgtc aaagtgaaac
     6061 ctgtaggtgt accaaacagc gaagctactt atttcgtcaa actgaaagac aaaaccgtag
     6121 ctcctcttat ggaactgact gaagagggtc ttatcaaatc aatcaatgtc ccctacagca
     6181 gtaacaatgc aaagaatgca gcaaacaatg ccgttgctcc ccaacgaaaa gccaatcccc
     6241 gcgactttct cacagaagaa attctgatgg caagttcaac cgccaagatg gccgaactgg
     6301 tagcaaagga aatctataat atccgcgaaa gtaaaaacgc attattgcgc ggacaagcag
     6361 ataatatgcc ttcggacggc gcacagctca aaatcatgct cgacaacctg aatcttcagg
     6421 aagaagccat gaccgagatg ttttcgggag tccgcaataa agaagaaaag acatttactg
     6481 tccgcctcac tccggataag gaattcgaca atgaggtagc tttccgcttt tcaaagaagc
     6541 tgggtatagt tgccaacaac gatttggcag gcactccatt ctacatcagt ctgaaagacc
     6601 tgaaaacggt gaagattccg caagaggacg ggaaaaagaa gaaagagatg gaaggcattg
     6661 cttataacgt accgggacag gcaatggtga cgctgacgga cggcaaaaag aaattgtatg
     6721 aaggagaaat acctgttact cagttcggta tcatagaata ccttgctccg gtattattca
     6781 acaagaactc gaccatcaaa gtttactttg atccggtgac cggtggacta ctgaaagtag
     6841 atagagaaga aagcaaataa aacctctaaa aaaacaaaac gatgggtggc gaaggacata
     6901 tgctcgacat gatacgtcgg ctgaaagacg gcaaagaagc ctcccgctta cgccgtgaac
     6961 ggagaaatga caagttaggg cgacttagaa gaaacaacga cccttatctt ctgccggata
     7021 cgactccgga agagatggaa cgcatcatca aggattcgga aaagaaaaaa gaaaaagata
     7081 acaactattt cgtatgggga acgctcatca ttatgggcgt actgatagga tgtgctgtcc
     7141 tcctgtgggc aatctttttt aatggataat tatccattta ataaatccgt ctttctgtaa
     7201 ttgggaaaga taggtagata cacgagactc gtagcctgct tcatattgaa agtggtctgc
     7261 gagtttttct ataatctcac gaaccgtccg ctgcccgtct atcaggttcc atacagccgt
     7321 accgtgttct tccagacgca catgaatatc tttggacatt cctttcggca ataaataacg
     7381 actcatccac gaacgtttaa aacgagggaa ggagagcaca atagtctccc cttcctgttc
     7441 agctttaata tgttcgttac gacaagggat cacctccagg aggtttattt tctctttcgt
     7501 agccatatct tttctctttt atatcttttc agatagaata tatactgtga ttatttctga
     7561 atatttgctt cttccagtcc gtagcctttc ttcttgtttt ccactttcag catcaaggca
     7621 acaatcaggg caagtacacc gaacatagca aaaatagcca tcggcaaagt ataatcataa
     7681 gtctgtgcac catctacaac cggacctttg caataagaat tcaacaccca tccgatcagc
     7741 aaaggcacgc ccatcaatcc ccagttctgt acccaaaaga tcaacgcata agccgttccc
     7801 aactgtttct ccggaataat cttcggaacc gaaggccaca ttgccgaagg aaccaatgag
     7861 aaagcaaatc ccagaataat catgatcacc gttgcaaacc accatatatt cagaatagga
     7921 agagcgaaca tcgtgtgtac gaaaatcagc atcaccgacc cgatcaccat cagcgtggct
     7981 cccttaccga tacggtcata taatgaaccg aacaacggtg tcaggatgat cgcgccaatc
     8041 ggcagcaatc cgggaatcgt tcccgcaagt ttcggatcaa cattgtactt ctgtaccatc
     8101 aaatcggccg catacttgat gaaggggaat acagccgaat agaacaatac gcacagtaat
     8161 gcgatcagcc agaatccttt gttggtaatg atatagacaa tgtctttcat gcggaaaggt
     8221 tcttccggtt ccagtccttc cgcatccagt gaagcatcca gtttcttatc gtagaaagta
     8281 tagatgaaga atgcgatggt acctacgcac aacatgacga gacagaacag aataggagcg
     8341 ggaatattgg tatggaatac gccgctctca tccgtagacc cgaagaagtc tgccaaagga
     8401 acggtaagca ccatggccaa agtcgttcca atacgcgcgg tcgccatttc cagtcccata
     8461 gcgagagcca tctctttgcc tttaaaccac ttcacgataa tcttcgaaac ggtgataccc
     8521 gcaatttcga ctcctacacc gaaaatagca taacccaatg cagccaatgt gacttgcatc
     8581 ttgaatccga aaagcatcgc accttccggg aaagtagtag taatagcata atatttcaat
     8641 ccacaaccga acaccatcaa taaacaggca cccattccgg tgaagcgtac tcccatctta
     8701 tccagaatga taccaccaaa gatgagcatc agcaggaata cattaaacca gccataagca
     8761 ctggtgaaaa aaccgtaatc taaactgtcc cagagaagtt ctttttcaag catgggtttc
     8821 agaggagaca taacgtctgt gaggaagtag ccgcacaaca tggtaaaagc gactaatgct
     8881 agaacactcc aacgcagcac tgcggagtca ttcagctttt gtttcaattg ttctgtcatt
     8941 gtaatattta aaaggagtta ataatctcgt aacgggcaac aaagttaact aattatcatt
     9001 tgttttacta aaaaaggaga acattttata agaaaaagga catctgaccg gatattcctg
     9061 tatgaagaag agcagaccgg gcccaataat aaagacaggc gcgaactaca cgtattacac
     9121 gattctatta gaatctcttg taattcgcgt aattcgcgcc tataatgaag agaacgggtc
     9181 aaaaagcccg ttcactcaat aagtttaaac cgaatatcct gtcactgaat tattctgctg
     9241 caggagcagg agtttcagta gccgaagctt ccgttgctgg tgcagactct gcaggagcag
     9301 tagcatctgt ctgaggagca gcagtaccgg taggcatatt atacgggttg gtttgttgtt
     9361 ctttctgtgc ttgttccaac aatacatctt tagccgcaga agaagaagga acaacgtaag
     9421 cagtagcaac gctcatcaca accatgaaga tagccagacc ccaagttgct ttttccagaa
     9481 aatctgtagt cttgcgcacg cccatgatag cgtttgatga agaaaaacca gaagcaagtc
     9541 cgcctccttt tgagttctga atcagcacga tgaagcacat cagcaaggct gcaatcacca
     9601 ttaagataat gaataataag tacattttta gttattttga attagcgtta ataatcaatt
     9661 tctcnnnnnn nnnnagcatt tttttttgga tatttcaagc ttaatttttt aattatttca
     9721 agagctttcg aatatcgttg ctgttttacg tagattttgg ccaaagtttc tgtgaaacag
     9781 ctgtcatctt cctcttctat ggtgttggtt tcagttgttt cgtctgttct gcccgtttcg
     9841 tttgtttcag cggaagaagc tgcctttgct ttctcttctt ccctcaaagg tttcaggtat
     9901 acgactggat cagtctcgct tttttcgata aagttgtcaa tcagctcgtg tcctttcagc
     9961 ttgggcattg cctctgccgg ctcgtcggcg acaggtgtct cttcgagaag gtatgccgta
    10021 tagtccatag agtaatcaaa gcttgtctga ctggttactt cttcgggagc cgtcgaaagg
    10081 aaagcatcga tcagagccag tgtccggtcg acggtaggct catctttcaa tacttcagag
    10141 agaggcaacc ctttcttctg ggattcgaca gcgaagcgtt cgccttcgat cagatgaaac
    10201 agtttccgtc ggtcggcaat atacagaacg gctttccgca gttccgcacc gaaattaatg
    10261 tcgtggagaa tatacaggtt cttgagatac aacaaccgga gcgactgaaa atacggatac
    10321 ctcgcgagct ggttgcgcag ttcgtacaaa gtatccctat tcagcgtctc gggatgctga
    10381 atccat
//
