LOCUS       c00439_gnlPro..         5051 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBGCMNJE_439.
ACCESSION   c00439_gnlPro..
VERSION     c00439_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:00:51
            Original ID  :: gnl|Prokka|CBGCMNJE_439
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5051
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5051
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10:4140]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      11..4140
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5051
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5051
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             11..1813
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg439_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.9e-218, bitscore:
                     714.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTKLFEDAAKLIVENAMKYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRAGGIIAILAELAKGG
                     LIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFNLVLGSQGAYYQELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRLID"
     CDS             1861..3558
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg439_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-48, bitscore:
                     152.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             3577..4140
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg439_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.7e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             4140..4883
                     /locus_tag="ctg439_4"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGNELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             4947..5051
                     /locus_tag="ctg439_5"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAV"
ORIGIN
        1 atagattgaa atgaaaaagc aattacgcag ttcgtttagt acacaaggcc gtcgcatggc
       61 gggagcccgc gcattatggg cagccaacgg catgaagaaa aatcagatgg gaaaacccat
      121 tatcgctatc gtcaattcgt ttacacaatt tgttccggga cacgtgcacc tgcatgaaat
      181 cgggcagttg gtgaaggcgg aaattgagaa gctgggatgc ttcgctgcgg aatttaatac
      241 gattgctatt gatgacggta tcgctatggg acatgacgga atgctttact cgcttccttc
      301 ccgtgatatc atagcggaca gcgtagaata tatggtcaat gcgcacaagg cggatgcaat
      361 ggtatgtatc agcaactgcg ataagattac cccagggatg ctgatggctg ccatgcgcct
      421 gaatatccct accgtatttg tatccggcgg accgatggaa gccggagagt ggaacggtca
      481 gcatctggac ttgatcgatg ccatgattaa atcggcggac gacagtgtaa gcgatcagga
      541 agtagcgaat atcgaacaga atgcctgtcc tacctgcgga tgttgttccg gaatgtttac
      601 ggcaaactcg atgaactgtc tgaatgaagc tatcggcttg gctcttccgg gaaacggcac
      661 aatcgtggct acgcacgaaa atcgtacgaa actgtttgaa gatgctgcca aactgattgt
      721 ggaaaatgca atgaaatatt atgaagaagg tgacgaaagt gtacttcccc gcagcatagc
      781 tacccgtcag gcattcctca atgccatgac gctggatatt gcgatgggcg gttctaccaa
      841 tacggtgctt cacctgttgg ccgtggcaca tgaggcagga gtcgatttca agatggacga
      901 catcgatatg ctgtcacgca agacaccctg cctgtgtaaa gtcgctccga atactcaaaa
      961 atatcatatt caggacgtta accgtgcggg tggcatcatt gctatcctgg cagagttggc
     1021 aaaaggcggt ctgattgata cttccgttct ccgtgtggat ggcatgtcgc tggcggaagc
     1081 gatcgatcaa tattcaatta ccagcccgaa cgttacggaa aaagcaatga gcaaatattc
     1141 aagtgcggca ggaaacagat tcaatctcgt acttggttct cagggagctt attatcagga
     1201 attagataaa gatcgcgcga acggatgtat ccgtgatctg gagcacgcct atagcaagga
     1261 cggaggtttg gcggtactga aaggaaatat cgctcaggac ggttgcgtag taaaaacggc
     1321 gggtgtagac gaaagcatct ggaagtttac cggacctgcc aaagtattcg actcacaaga
     1381 agcagcctgt gaaggcatcc tcggaggccg agtcgtcagc ggcgacgttg tcgtcatcac
     1441 gcacgaaggt ccgaagggcg gtcccggtat gcaggaaatg ctttacccga cttcttatat
     1501 caaatcccgt cacctcggca aagaatgtgc cttgattacc gacggacgtt tcagtggtgg
     1561 aacttccgga ttgagtatcg gacacgtttc tcccgaagcc gctgccggag gtaatatagg
     1621 aaaaatagta gatggagata tcatcgaaat cgacattccc gcccgaacga ttaacgtgcg
     1681 actaacagat gaagaactgg ctgcccgccc gatgactccc gtcacccgtg accgttacgt
     1741 gccgaagagc ctgaaagcat acgccagcat ggtaagctct gccgataagg gagcagtgag
     1801 attaatagac tgatccactt cattatccat tatgaatcat ccattatcca ttaaagaact
     1861 atgagtaagg acttaataac aggcgcagag gcaatgatgc gctctctgga acatcaggga
     1921 gtgactacca ttttcggtta tcccggcggt tccatcatgc ctacgttcga tgccctgtac
     1981 gaccatcaaa atacattgaa ccatatcttg gttcgccatg aacagggagc tgcccatgcg
     2041 gcacaaggct acgcccgtgt atcgggtaaa gtcggtgttt gcttggtgac aagcggcccc
     2101 ggagcaacca atacgatcac aggtattgca gatgcgatga tagacagtac gcctatcgtt
     2161 gtcattgcag gacaggtggg aacaggcttt cttggaacag acgcttttca ggaagtcgat
     2221 ctcgtaggta tcactcagcc aatcgctaaa tggagctatc agattcgccg tgccgaagac
     2281 gtagcctggg cgatagcacg tgctttctac attgccagta gtggtcgtcc cggtccggtg
     2341 gtactcgact ttgccaagaa tgcgcaggtt gaaaaaacga aatacgagcc gacaaagcag
     2401 gagtttatcc gcagctatgt tccggttccc gatacagacg aagaatcggt aaaggctgcc
     2461 gccgaactga tcaataacgc cgaacgcccg cttgtcttgg taggacaggg agtggaactg
     2521 ggaagcgctc aggaagaact gcgtatcttt atcgaaaagg cggatatgcc cgcaggttgt
     2581 accttgctcg gactttccgc attgcctacc gaccatccgt tgaataaagg aatgctgggt
     2641 atgcacggaa atctgggacc gaatatcaat actaacaaat gtgatgtact gattgctgtc
     2701 ggtatgcgtt tcgacgaccg tgtgaccggt aatctggcta cttacgccaa acaagcgaaa
     2761 gtgatccatt ttgacattga tccggcggaa gtaaataaga atgtaaaggt agatattgcc
     2821 gttttgggcg actgcaaaaa gacgctggct gctgtgactg gactgttgaa aaagaaccgg
     2881 cacaccgagt gggtcgatag tttcaaggaa tatgaagcgg tagaggaaga aaaagtcatt
     2941 cgtcctgaac ttcatcctgc aacggattca ctgagtatgg gcgaagtggt gcgtgcggta
     3001 agcgaagcga cccgtcacga agccatattg gtgacagatg taggtcagaa tcagatgatc
     3061 tctgcccgct actttaaata taccagggaa cgtagtatcg ttacttcggg tggactcggc
     3121 acgatgggtt ttggccttcc ggcagctatc ggagctactt tcggccgtcc cgaccgcact
     3181 gtatgtgtat ttatgggtga cggcggactg caaatgaaca ttcaggagct gggtacgatc
     3241 atggaacaga aagctccggt gaagattatc tgcctgaaca acaattatct cggcaacgtg
     3301 cgccaatggc aggctatgtt ctttaatcgc cgttattcat ttactccgat gctgaatccg
     3361 gattacatga aaatcgcttc cgcctacgat attccttcca aacgtgtctt ttcacgggaa
     3421 gaattgaaag cggctatcga cgaaatgctt tcgacagacg ggccgttcct gctcgaagcc
     3481 tgtgtggtag aagaaggcaa tgtcctgccg atgacccctc cgggcggttc agtcaatcag
     3541 atgttgctgg aatgttaatc cttaatttag aaagttatga gtgataagac attatatacg
     3601 attatagttc attctgaaaa tatagccgga ttgctgaatc aggtgaccgc tgtatttacc
     3661 cgtcggcaaa taaacatcga gagtttgaac gtttctgctt cttccattaa aggagtacat
     3721 aaatatacga ttacagcgtg gactgataag gacactatcg aaaaggtggt gaagcagatc
     3781 gaaaagaaga ttgatgtgat tcaggcgcac tattttacgg aagacgagat ttatttccat
     3841 gagatagcct tatataaggt atctactcct gcttttcagg agactccgga agcatctaaa
     3901 gtgatccgca gatataatgc ccgcattgta gaggtgaatc cggtattctc tatcgtcgag
     3961 aagaacggca tgagtgaaga gattacttcc ctttacgaag aacttcgggc tttgaaatgt
     4021 gtgctgcaat ttgtccgttc gggccgtgtg gctattacta ccagctgttt cgaacgtgtg
     4081 aatgagttcc tggacggaca ggaagcgaag tataagcaaa gtaaaaagga acaggagtaa
     4141 tgagtgaaga aaataaaata gggacttatc agtttgtggc agagccgttt cacgtagatt
     4201 ttaacggccg cctgaccatg ggcgtgctgg ggaatcatct gctgaattgc gcaggttttc
     4261 atgccagcga ccgtggattt ggtattgcta cgctgaacga ggacaattac acatgggtgc
     4321 tttcccgtct ggcgatcgag ctggacgaga tgccttacca atacgagaag ttctcggttc
     4381 agacatgggt ggagaatgtc tatcgtctct ttaccgaccg taactttgcc gtcattgaca
     4441 aggatggaaa gaagatcggc tatgcccgtt ccgtatgggc gatgatcaat ctgaatactc
     4501 gtaagcctgc cgatctgttg gcattgcatg gaggaagcat cgtcgattat atatgcgatg
     4561 aaccctgccc gatagaaaag ccttcgcgta tcaaggtgac aagcaatcag cctgttgcga
     4621 cgctgacggc aaaatacagt gatatcgata ttaacggaca cgtaaacagt attcgttata
     4681 tcgagcacat acttgacttg tttccgatag aactgtatca gacgaaacgt atccgccggt
     4741 ttgaaatggc gtatgtggct gaaagttatt tcggaaatga actctctttc ttctgtgatg
     4801 aggtgagtga aaacgagttt catgtagagg tgaagaaaaa cggcagcgag gtagtatgcc
     4861 gttccaaagt gatatttgaa taatatagag tataaaatca attaataaca gatggcgcaa
     4921 gtcatcaaaa caaaaaaaca aaaaaaatgg cacagttgaa ttttggcgga actgtagaaa
     4981 atgtagttat ccgtgatgaa tttccattgg aaaaagctcg tgaagtattg aaaaatgaaa
     5041 caatcgctgt a
//
