LOCUS       c00046_gnlPro..        24857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EDPDJOAC_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 21:51:54
            Original ID  :: gnl|Prokka|EDPDJOAC_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 58561
            Orig. end    :: 83418
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24857
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[68561:73418]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="2"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(25..966)
                     /locus_tag="ctg46_62"
                     /transl_table=11
                     /translation="MKTKITGLLTFLIGTFFFYSCDTDVEALEIQKLKTYDEQYFENLR
                     AFKKSDHEISYAYYEAWSPIEGVTGYKDPASWGERMVGLPDSIDIVNLWMGIPTAETHP
                     IAYADMQYCQRKLGTRFVMHADASHYRHQFTVDGVDYDLSQNKDDEAMAAYAKWIVNQV
                     LEPGLDGVDVDWEGWSGSDLVRLIKELGKYFGPEGEQPDKLLIVDYFSGTPPTDIIPYC
                     DYIVQQAYSDQVGFLTQPSNFPPEKMIYCESFGVFYADGGQLMNYARWEPSKGRKGGCG
                     VFYLGRNYYSSSGIPYNEFREAIQIMNPAVNE"
     CDS             complement(1009..2604)
                     /locus_tag="ctg46_63"
                     /transl_table=11
                     /translation="MILNKILSWNKLSILGISLMLLNNISCIDYEDNVNPNEVTEEMME
                     VDNLKTGAFFSQMLRRVVIINDGDKLDSDYQIAQNLSHDLYSGYIAATLGSTNHNGQYN
                     FQEQWVNATFDYAYTGIMAPWQSIHKIATEQELPEVDALATIVKVEGMHRIADTFGPIP
                     YVNYGSSSLYDALDLVYNKFFEELDNAIEVLSNYVNGNVDAKLMSDYDCVYGGDVEKWV
                     KFANTLRLRLAIRVSYANPTLAEAQAKKSMENMFGFIESKAERAELSHNSLEYHHPLHE
                     IAYNFNSGDCRPGATIVAYLNGLNDSRISSYFTAADDGEYHGVRIGITTSNMSNYQGNK
                     ISNLNINRASTPVVWMTAAESFFLRAEGALRGWDMGGTAKSFYEQGVRMSFEENNAAGV
                     DDYLADHTSTPGAFADNVGSDNYTFSSRVTPAWDDNAGFEAQLERIITQKWIANYPDGP
                     EGWSEYRRTGYPEVIPVVRNSSNGTIDTQLQVRRLPYTRDEKINNASGVASGISALGGQ
                     DTGGAKLWWDKKSR"
     CDS             complement(2629..5928)
                     /locus_tag="ctg46_64"
                     /transl_table=11
                     /translation="MRISLALLSAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSGKILDILDDIFKGTDITYTVVDKQIILSTNKMQL
                     VQQEGQIQIKGVVKDAGGDPLIGVNVKVKDSTVGTITDINGNFTLQTRKGDILEISYVG
                     YATKTVKVQNAQVLNIVLTEDTEVLNEVVVTALGIKKEAKSLSYNVQQVSNAEITRIAD
                     ANFVNNLNGKVAGVTINSSSAGVGGSSRVVMRGTKSLNGNNNALYVVDGIPMSDMSAAS
                     TQPTDSYEGAGQSGDPISGLNPEDIESISVLSGPSAAALYGSAAANGVVMITTKKGREG
                     RTSVSISNNTTFSAPLVLPEFQNTYGQTEVGSYYSWGSKLNTPSSYDPKDFFQTGVNVT
                     NAASLSTGTDKNQTYLSLGTTNAKGIIHNNDYERYNVTVRNVAKMLKDKLTLDLSFMLS
                     SVKEQNMTSQGLYYNPLVPLYLFPAGDDFSKVQAYQRYDSERNLLTQYWPYSTSLALQN
                     PYWITEHIKIPNHKNRYMATASAKYEFADWINVTARAKMDRNNERRERMYDAGTNTLFA
                     SKYGYYSKSNIENQQIYGELLLNINKYFVDNTLNVTANVGGNFENNDYQSDYFGGKLKS
                     VANLFTFGNVDTSEKNLANQYGYHLKKRAIFGSAQIGYKSMAYLDVTARNDWSSTFKGT
                     NTGSFFYPSIGLSGIITDIFRCSTDIMPYMKVRISYSEVGNSPDVFLAIPTYALVDGVP
                     VTQSRRPNPNLKPERTKSWEAGFNFVFFKNRLRLDGSIYQSRTYNQFFERTLSSTTGYK
                     SEVVNGGRVDNKGIELSLRFEDKWGNFGWSSYLTYSLNRNKVVELLRNYEDPYTHELTS
                     LDRIDMGGTSMYKMILTEGGSIGDIYVNTLRTDEHGAIYVHPSDQVVVTQPDEFVKAGN
                     SAPKYNLGWGNTFSYKGLSLGFLFTARVGGVVVSQTQATMDAYGSSKATAIARDNGGAI
                     VNGRPIGAEDYYTKIGGAGAQGGIGSMYTYSATNVRLAELSLGYDIPINKYVDWIKGLN
                     VSFIGKNLFFLYRKAPFDPELTASTGTYFQGIDMFMSPSLRNLGFSVKVNF"
     CDS             complement(6178..7101)
                     /locus_tag="ctg46_65"
                     /transl_table=11
                     /translation="MENMNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRR
                     SMYNQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVV
                     WLNSGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVN
                     AYEDDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWK
                     DGKLIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAA
                     LKWRTEEAVQQADDTFTKKKIIVDLY"
     CDS             7326..7895
                     /locus_tag="ctg46_66"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(7869..8975)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_67"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-16, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIEK
                     LLQSFIPVPFVITSVPDQRLGQAVTLLIEGQMEISALETKLESVLAPYYRPKYIYQVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(8972..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_68"
                     /sec_met_domain="MR_MLE_C (E-value: 2.6e-28, bitscore:
                     92.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSFKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_69"
                     /sec_met_domain="ECH_1 (E-value: 3e-81, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(10829..12496)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_70"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-07, bitscore:
                     23.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKIIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIAIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(12516..13628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_71"
                     /sec_met_domain="Chorismate_bind (E-value: 4.6e-57,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRVDKSCPIVLIQSDRTGQPLPMEIVAEEEQGLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(13625..14857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_72"
                     /sec_met_domain="HBT (E-value: 3.1e-16, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELNVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(14942..15304)
                     /locus_tag="ctg46_73"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHLVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(15375..17144)
                     /locus_tag="ctg46_74"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTGM
                     TPYEFKKAQESLG"
     CDS             complement(17523..18290)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_75"
                     /sec_met_domain="Acetyltransf_1 (E-value: 5.1e-07,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVGVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             complement(18626..19876)
                     /locus_tag="ctg46_76"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFAQMPEIKLGQSISFEEYLNRV
                     AKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLEAVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALESACGIWDICF"
     CDS             complement(19854..22961)
                     /locus_tag="ctg46_77"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVFLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITRFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSITTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPAFYYLVENNVLNKKKNDEKEYTI"
     CDS             complement(22968..24077)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_78"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 8.8e-09,
                     bitscore: 28.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMKRELHTFIIGSVLFFTACGDKQESEQKSGYRIQGDTVYIADP
                     LLLEKIKVSVSELKPYSKKVITSGVVRPIPPRYAYVAPPFAGRVTKSYVRIGQSVRQGT
                     PLFEISSPDFTSAQKEYFQALSSRELAKKDLKRKEDLIRNGVSSQRELEEAQNALLIAD
                     KEFENASAALRVYQVDNPAEMILGQPMIVRSPIPGEVIKDNIVTGQYLKDDTEPIAIVA
                     DLSKVWIAAQVKEKDIRFINEGSSLDIEISALPGTVIKGNVYHVEEEVDEETRSIQVLS
                     VCDNLNGHLKLGMYTTVHFLSVPVGQIQIPEKALLQGEKDSYVFVQIAPLVFVRTSVTV
                     ETTENGIAVISEGLRPGDKIISEGGYYLK"
ORIGIN
        1 tcatgattct tatttattca ttgtttactc atttacagca ggattcatta tctgaatagc
       61 ctcccggaat tcattataag gtatacccga tgaagaataa taatttcttc ctaagtagaa
      121 tactccacaa ccgcctttac ggcctttcga cggttcccaa cgtgcatagt tcataagttg
      181 tcccccatcg gcatagaata ctccgaacga ttcgcagtaa atcatcttct cgggtggaaa
      241 gttactgggt tgagtcaaga accccacttg atcactataa gcctgttgaa cgatataatc
      301 acaataaggt atgatgtctg ttggtggtgt tccactaaag tagtcaacga taagcaactt
      361 atccggctgt tcgccttcag gaccaaaata cttgccaagt tcctttatca atctgaccaa
      421 atcggaacca ctccaacctt cccagtcaac gtctactcca tcaagtcccg gttccaacac
      481 ttgattcaca atccattttg catatgcagc catcgcttca tcgtccttat tctggctaag
      541 atcataatca accccatcaa cggtaaactg gtgtctgtaa tgagaagcat cggcatgcat
      601 gacaaaacgt gtacccaatt tccgctggca gtattgcata tccgcatatg ctatcggatg
      661 tgtctctgct gtcggtattc ccatccaaag atttacaata tctatactgt caggtagtcc
      721 taccatacgt tcaccccacg acgcgggatc tttatagcct gtcacacctt caatcggtga
      781 ccacgcttcg taataagcat aacttatctc atgatcgctt ttcttgaaag cacgcagatt
      841 ctcaaaatac tgctcgtcat atgttttcag cttctgaatt tctaacgctt ccacatcggt
      901 atcacaacta tagaaaaaga atgttccgat aaggaaagtc agtaaacctg ttatttttgt
      961 tttcatcgta attagtgttt ttagaattaa acaatgtcca ttctcctgtt atcgggattt
     1021 tttgtcccac cagagtttag ctccacccgt atcctgacca cccaaagccg atataccact
     1081 ggcaacgccg ctagcattgt tgatcttctc gtcgcgtgta taaggcagac ggcggacttg
     1141 taactgggta tcaatcgtac cattactact gtttcttact acaggaataa cttccggata
     1201 gcctgtacga cgatattcac tccagccttc gggaccgtcg ggataattgg caatccactt
     1261 ctgtgtaatg atgcgttcca actgagcttc aaatccggca ttatcatccc atgcaggagt
     1321 aaccctgctg ctgaaagtat aattatcact acccacattg tctgcaaaag cacccggagt
     1381 cgaagtatga tcagccaaat aatcgtctac accggcggca ttattctcct caaacgacat
     1441 gcgtacacct tgctcataga atgatttggc cgttccaccc atatcccagc cacgtaatgc
     1501 accttcggca cgcaggaaga acgattcggc agccgtcatc catactaccg gagtagaagc
     1561 acggttaata ttcagattag agattttatt gccttgataa ttgctcatat tgcttgttgt
     1621 gataccaata cgtacgccat gatattcacc gtcatcggct gctgtaaaat aagagctgat
     1681 tcgcgaatca ttcagtccgt tcaaataggc tacgatggta gcacccggac gacagtcacc
     1741 cgaattgaag ttataggcaa tctcgtgcaa cggatgatga tattccaatg aattatgcga
     1801 aagttcggca cgttccgctt tactttcgat aaagccgaac atgttttcca tcgacttctt
     1861 tgcctgtgct tctgccagtg tgggattcgc atatgaaaca cgtatagcaa gacgcaaacg
     1921 cagtgtgttg gcgaacttca cccacttctc tacgtccccc ccatatacac agtcatagtc
     1981 actcatcagc ttagcatcca catttccgtt cacataattg ctcaatactt cgatagcatt
     2041 atccagttct tcaaaaaact tattataaac caaatccaat gcgtcatata agctggaaga
     2101 gccatagttt acatatggaa taggaccaaa tgtatcagca atacggtgca tgccttctac
     2161 ctttacgatg gtagccaatg cgtcaacttc cggcagttcc tgttcagtgg ctattttgtg
     2221 aatactttgc catggtgcca taattccggt ataggcataa tcaaaagtgg cattcaccca
     2281 ttgttcctga aagttatact gcccgttatg attggtagat cctaaggtag cggcaatata
     2341 gcccgaataa aggtcatgcg ataagttctg agcaatctga tagtcagagt cgagcttgtc
     2401 gccatcattt atgattacaa cccgacgcag catttgcgaa aagaaagcac ccgtcttcaa
     2461 gttgtctact tccatcattt cctcggtgac ttcattcgga tttacgttat cctcatagtc
     2521 gatacacgaa atgttattta atagcatcaa agatatcccg agaatggaaa gtttgttcca
     2581 tgatagtatt ttatttaata tcatatcttc tacaatttat aagtttgatt agaaattaac
     2641 tttcacagag aatcccaaat tacgcagact tggcgacata aacatgtcga taccttgaaa
     2701 gtaagtgcct gtacttgctg tcagttccgg atcgaacgga gcttttctat aaaggaaaaa
     2761 gagattctta ccgatgaaag atacgttcaa ccccttaatc cagtccacat acttgttgat
     2821 aggaatatca tagcctaacg ataactcagc caaacggaca ttagtcgcac tgtaggtgta
     2881 catagaacca ataccaccct gagcacctgc acctccaatt ttcgtatagt aatcttccgc
     2941 accgattgga cgaccgttaa caatggctcc gccattatca cgggcaatag ctgtagcctt
     3001 tgaagagccg tatgcgtcca tcgtcgcctg tgtctgtgat acaactacac caccgacacg
     3061 tgccgtgaac aggaatccca atgaaagccc tttgtaactg aatgtgtttc cccaaccgag
     3121 gttatactta ggagcactat taccagcctt tacaaattca tcaggctgag taactacaac
     3181 ctggtccgaa ggatggacat agatagctcc atgttcgtcc gtgcgaagcg tattcacata
     3241 aatatcgccg atagatccgc cttctgtcag tatcatttta tacatacttg tcccgcccat
     3301 atcaattcta tccaaagaag taagttcgtg cgtataagga tcttcatagt tgcgcagcaa
     3361 ttccaccact ttatttcggt tcaatgaata ggtcagatac gaactccagc caaaatttcc
     3421 ccatttgtcc tcaaaacgca aagacaattc gataccttta ttatctacac gaccgccatt
     3481 gactacttcc gatttatagc cggtagtaga agaaagggta cgttcaaaga actgattgta
     3541 ggtacgtgac tgatagatag atccatccaa tctcaaacgg ttcttgaaga agacaaagtt
     3601 aaatccggct tcccatgatt tggtacgttc cggcttcaga ttggggttag gacgtcggga
     3661 ctgagtaaca ggaacgccat caaccaacgc ataagtcgga atagccagaa atacatccgg
     3721 tgaattacct acttccgaat aagaaatacg tactttcatg tatggcataa tatccgtact
     3781 gcaacggaat atatctgtga taatccccga aagaccgata gacggataga agaaagaacc
     3841 ggtattcgtc cctttgaagg tagatgacca gtcgttacga gccgtcacat ccagataagc
     3901 catagacttg taaccgatct gagcactacc gaatatggcg cgttttttca aatgatagcc
     3961 atattggttg gccagattct tctctgaagt atccacgttg ccaaaagtaa agaggttggc
     4021 taccgacttc agtttgcctc cgaaataatc agactgataa tcattgtttt caaagttccc
     4081 acccacatta gctgttacat ttagggtatt atcgacaaag tacttattaa tattcagcaa
     4141 taattcaccg tatatctgtt gattctcgat attactcttg gagtaataac cgtatttaga
     4201 agcaaacaaa gtatttgttc cggcatcata catgcgctca cggcgttcgt tgttgcggtc
     4261 cattttggca cgggctgtta cattaatcca gtcagcaaat tcatattttg ccgatgcagt
     4321 tgccatataa cggttcttat gattaggtat tttaatatgc tcggtaatcc agtatggatt
     4381 ctgtaaagcc agacttgtgc tgtaaggcca gtactgagtc agtaaatttc gttccgaatc
     4441 ataccgctga tatgcctgta ctttggagaa atcatctccc gcaggaaata gataaagagg
     4501 tactaacggg ttataataaa gtccctgaga ggtcatattt tgttctttta cagagctaag
     4561 cataaaactc aggtcaagag tcagcttatc tttcagcatc ttggcaacat tacggacagt
     4621 gacattgtaa cgttcgtagt cattattatg gataatacct ttggcattgg tagtacctaa
     4681 agataagtaa gtctgattct tgtcagtacc tgtagaaaga ctggcagcat ttgttacatt
     4741 cacacctgtc tgaaagaagt ctttaggatc atagctgctc ggcgtattca atttactgcc
     4801 ccagctgtag taactaccca cttctgtctg cccataagta ttttgaaatt cgggcaagac
     4861 aagaggagcg gagaaagtcg tattattgga tatgctgact gaagtacgtc cttccctacc
     4921 ttttttagta gtaatcatca caacaccatt ggcagcggca ctaccgtaaa gagctgcagc
     4981 tgacggtcca ctcaaaacag agatactctc tatatcctcg ggattcagac cggaaatagg
     5041 atcaccggac tgaccggcac cttcgtatga gtccgtaggc tgtgtagaag cggcactcat
     5101 atcactcatc gggataccat caaccacata aagagcattg ttattaccat tcaatgattt
     5161 ggttccacgc atcactacac gtgaagagcc accgacacca gctgaagatg agttaattgt
     5221 aacacccgca actttaccgt tcagattatt gacgaagttg gcatctgcaa tgcgtgtaat
     5281 ctcggcattg cttacttgct gtacattgta tgacaaagat ttagcttcct tcttgatacc
     5341 caatgcagta acaacgactt cattcagtac ttctgtatct tctgtcagca caatattcag
     5401 aacttgggca ttctgtacct ttactgtttt cgtggcatat cccacataag aaatttccag
     5461 aatatctcct ttcctggtct gtagcgtaaa gtttccgttt atatcggtga tagtaccgac
     5521 cgtagaatct ttcactttca cattcacacc gatcaaggga tctccgccag catctttcac
     5581 aactcctttt atttggattt gtccttcctg ctgaacaagt tgcattttat tagtcgataa
     5641 aataatctgc ttgtcaacta cggtatacgt aatatcggtc cccttaaaaa tatcatctag
     5701 aatatccaga atcttacctg atttatttct cacagaaaca atacgattct tctgaatcgt
     5761 tttgtcattg taaaggaaaa cataatcgga agcttcttct attttattca gtacctgttc
     5821 tacagataca ttgttcatag aaatggcaac atgcgtccgt tgagcatagc cattctctgc
     5881 agatagttgt aaaacgactg cagaaagtag tgccagacta atcctcataa ctaaaggtag
     5941 ttttagattt aaagcatatt taggatataa tgcaataaat gaatgatttt ttttcataca
     6001 tttgcggtta actaaagttt attactataa tgaactgtgg tttgattccg gttagcgttt
     6061 gcaagactcc ttaccgcgaa tctgaaaaat tgggggaaga cagctgttgg tagcagcttt
     6121 cttccttttt ttacgatctt tgtgttatct cataggctat tctcattttt atggttacta
     6181 atataaatct actattatct ttttctttgt gaatgtatca tctgcctgtt gtaccgcctc
     6241 ctcagttctc cacttcaagg cagcagactt agccagataa tccaatatct gtggcagtgt
     6301 ttcattacgg aaggtcgcac gatatttata ttcttttccc gatatattat taaactgaat
     6361 atctacatta aaatgccgtg ccagccgttt gaatatttca cccaactcgg cattgcggaa
     6421 tatcaactta ccgtctttcc atgccacctt ttcataaaca tccacttttc ccttcaacaa
     6481 tttctgatct accttattat aaagcaatcg ttctcctgga gctaactgaa ctgttgtttt
     6541 tccgtccggt gaaataacgt ttactttacc cttttctaat accgtttcta tactattatc
     6601 atcttcgtaa gcattcacat taaatttggt tccgtacaca tagacactta acccggcagg
     6661 agtattgacg taaaaaggcc gtttcctgtc cgcttctact tcaaaatagg cttcaccttt
     6721 taattcaaca ttacgattat ctttcttaaa aacggtagga taacgtaaag tactaccgga
     6781 gtttaaccag acaaccgaat ggtcaggaag ttcgtaacga atgactgaac ctgtagccgc
     6841 catgacttct gcatacttct cttcagtatc cgttgctccc caatataaat atcccaaaat
     6901 caaagaagaa agtaataaag gtatagtcaa gaatgcagca taacgcatca actgattata
     6961 catactcctt cttctgtttg tctttatttg ggtctgtgct tgttgatagg cacccattac
     7021 atcaatagac tccatttcct taatatcctc tcctaatgcc tgcgcttttc ggagcaatga
     7081 ttccggattc atattttcca tattctcttt caaaatctta tcttttaatt gcaattacac
     7141 taatagtaca actgaggtaa tcgaaaaggg acaggtataa catacttttt tttattttat
     7201 tttttaagct atcttatttt ccacagcttc ataccaaaaa caaaaaaaga aagaaaattt
     7261 taggaaatgc tgattttctt attatatatt tgcagtaaaa tgaaaaacta cagaatctca
     7321 aaataatgaa aatatctttt tccagacaga ctaaagaaag agctttcaaa caactttacg
     7381 aggattatta tgcccctttc tgcctgtatg caaaaagatt tgtagatgat aaagaagtcc
     7441 gcgaggacat tgtttcggat gtattcacct ccctatggga caagttggat accgactctt
     7501 tcgatttgca atcagagaca gcattgggat atataaaaat gtgtgtaaaa aacagctgtt
     7561 tgaactttct gaaacatcag gagtatgaat ggagttatgc cgaaaatatc caaaagaaag
     7621 ctcctctata tgaaacagaa acagatagtg tatatacact tgatgagtta taccgaatgc
     7681 tatacgaaac attaaataag cttccggaaa actatcgcac cgtatttatg aagagtttct
     7741 ttgaaggcaa aacacatgcg gaaattgccg aagaaatgaa tctcagcgta aaatccatta
     7801 atcggtataa acaaaaaaca atggaactcc tgcggaacga gttgaaagat tacctcccgc
     7861 tatttttatt attcctgtct cccgagcaac tgtaagctct ctgctaaaac acggcactct
     7921 ttacgattaa tcttcccatt tcccgtttga ggaatatgat ttacctgata aatatattta
     7981 ggacgataat aaggtgctaa gactgattcc aatttagtct ctagcgcact tatttccatc
     8041 tgcccttcta tcaataaagt aacagcctgc cccaaacgtt gatccggaac ggaagtgatt
     8101 acaaacggga caggaataaa cgactgaagt aacttttcga tctcttctgc ctgcacttta
     8161 attcctccgc tattgattac attatccttt cttcccagaa tcgtaaaact accgtccgga
     8221 taaatgcggg caatatcatt tgtctgcaga gtatcatcgc agacaagcgg agcattaatc
     8281 atcaaagtat tttctgaaga caaaaacaac tctacggatg aaaaaggata ataacgatcg
     8341 gatgctgctg cgccattcag acggcgaaga gcgatgtgag aaagggtttc cgtcatcccg
     8401 taagttgaat aaacagcatt ggacagattt ctgatttttt cctctaaagc cttgtcaact
     8461 gctccgcctc ctataattaa aatctccgtt tgctttaatt tctctttctc ttcgggtatc
     8521 tgaaatgtat tatacacctg caaaggcacc atagccgcaa accttaaagg agtgtccaca
     8581 tctgccaatg gatgaccgga agcccgacgt actataagat tcaacccggc aatcaaagaa
     8641 cggacgacta ccatcatcgc cccgatatag cgaaggttca tacacaataa tgccgtttca
     8701 ccctgcttta aatccagaaa ctcacaagtc aggcgtgcac tctgtatcat ctgatctttg
     8761 cgaacaagca attctttagg tgcccccgta gaaccggaag tatgtacagt gatcacagga
     8821 tcatcattaa accattcgtt tagaaaaaga tacaagtccc atatagcaga agggtggttt
     8881 ccctcacctt ctgctacaag gctatgtata tcgcccggag tatattcctt tccctccagc
     8941 aacaaacgct gtttttgtcg gtcgaatatc atcatttaca aaaccacaaa caatcttttc
     9001 tgatttcaag aggcatctct acattatctg taaagagtaa cccggtgcct aacccttgcg
     9061 gcaatggatt ctgaaaagta gcacaccatt gagcgatagc attcagaccg atattagact
     9121 ccagagcaga agttatccac caaccgatat tcagtttctc cgcttctgca atccactcct
     9181 cgccaccggc taatccgcca tgaagagaag gtttgataat aatatattgc ggacggatag
     9241 ccgaaagtaa tctttgcttt tcttcccagg tattatagcc tatcagttcc tcatccaaag
     9301 ctatcggcaa aggagattcg gaagtaagac gtgccatttc ttcccattgt ccggcacgaa
     9361 tgggctgttc tatcgaatgt aagtccagtt cggacaagcg tttcaatttc tccatcgcat
     9421 ctgttggcga gaatgctccg ttggcatcta cacgcaattc tatttcttta aaagaatagt
     9481 gagagcggat atgttggagt aaagccagtt cttcttcaaa gttgatggca ccgatcttca
     9541 actttataca gcggaatccc gcctccatct tcttctctat ctgagcaagc attctattga
     9601 agtcacccat ccagataagc ccgtttatcg gaatacctgc ttccccacgt gagaagggtg
     9661 tatcccacaa agcccagctt ccttcaaaaa agtgacgaat ggctgtctcc aagccaaaaa
     9721 ggatggaagg gtacttgcat agagcttcca tgtccagctt acctccctga ttctctacct
     9781 gccggcagat tttagccagc acttcctcgt aatcgggaag atcatcacag ctaagatttg
     9841 gcagaggagc gcactccccg atccctaccc aattgggaaa ttcgggagca gtaaaatgaa
     9901 gataccagac ttttcgcgtt gtgtatgtgc ctcgtgaagt tccggccggc tgcttgaaat
     9961 gaagcacccg cggaataatg tctattttgc aatccattgt ttaagggaac ttcggatatt
    10021 tcttaaagtt aggtttacgt ttctccagaa atgcattctt tccttcctga gcctcatccg
    10081 tcagatagta aagcaaggtc gcatcccctg ccagctcctg aatacctgcc tggccgtcca
    10141 gttcggcatt caatccggct ttaatcatcc gcaaggccaa cggactgagc agcatcattt
    10201 cttccgccca ttgcacatac tcatcctcca gttgctccaa tggaactact ttattcacca
    10261 atcccatatc caacgcttcc tgcgcattgt atttccggca aaggaaccat atctcacgtg
    10321 ccttcttctg accgacgaca cgagccagat aagaggctcc gaaacctgca tcaaagctac
    10381 ctacgcgagg accggtctgt ccgaagatcg cattctccga agcaatcgat aaatcgcaaa
    10441 ctacatgaag cacgtgtccg ccaccaatgg caaatccatt tacggcagca attaccggtt
    10501 tcggaatgct gcggatttgt ttctgtacat ccagaacact cagacgggga acaccgtcct
    10561 tgccgatata gccgccacgc cctttcacat tctggtcacc gcccgaacag aaagccttgt
    10621 caccagctcc cgtaatcacg atcacatcaa tatccgcttc ttcccggcaa atgcgcaatg
    10681 cgtcactcat ttcagccgtt gtagtcggag taaatgcatt tcgatagcgt tcacggttaa
    10741 tggtgatgcg ggcaatccca ttatagtaat caaagaggat atcttcgtat tctctgatgg
    10801 ttgtccattc tctttgtgtt gacataatct atttttgttt tagttgatga taataatctt
    10861 tcagtatacg tgcatcttta tttttattgc tgaatacttc catcagaacc ggttgttcca
    10921 tggcttccgg ttgtgtgaag gttttcatcg cttcggcaag ctgttcttca ttctctaccc
    10981 gttgataaag gaatccgcgt tcttccgccc atcctttggc agatgtcttg tgaacggctg
    11041 taatatactt gtgcgatgta cccgacatat ccagtccggg taatgtatgg aaaatctccc
    11101 ctcctccgtt attcagcaaa agaatgcgta gattaggacg gacattgata ttccacaaag
    11161 cattcatatc ataaaagaaa ctaaggtcac ctatagctat aaaatttagt ttatccgaac
    11221 cggcagcata tcccactgcc gtggacaacg agccttcgat gccgcttgta ccccgattac
    11281 agcatacctc aatcgtagaa ggaacctggt ataactgagc atagcggata acagaactat
    11341 ttgccagatg caatgcacat gattccggca atgcttttat caaagcaccg atagccgaca
    11401 tttccgaata tccgaactcc ggttcgggaa tgatcttgca ataattctcc catacacggg
    11461 gatactccgg cacgcggtta tccagcaatg gagctatttt ctccagaaac tcaaacgggt
    11521 ccatttcgat gacggtagtc agagaaccgt aaaggtcaac cacttctcca tcagcagaca
    11581 catgccagtg ttctttaggc ggatgctgcc gaagatattt tttcaaccgc ttggaaacca
    11641 catgtccgcc ataagtaatc aataactcgg gagtcatctg gccggttttc tcttcgggca
    11701 tcgcataaag cgccgcatca aaattcttca ctggaatacc gggtactgtc tgattaccga
    11761 tatgctcggt cagccacacg aaatgtttat ataacaattt ggtatgccgt ttctcaaaca
    11821 agtaaatcaa gttcatctgt ccgacaataa tcatccgctt ctgatatctg ttcaagcgtt
    11881 cgatcaggtc attgtaatcc cggtcgtata cattcagccc ctgatagcgc gtgatgacac
    11941 gtacttcggg aagcgactcc accgtaaact ggaacaaagg ttcggatata ggaatattaa
    12001 tatgtaccgg accttttcca tgatggttgg tttccagcaa ggcttcattc accaagcggt
    12061 tacagtacca ttcatcctct tctgtctgaa tctccggaag gtttaccgac ttcttgacca
    12121 atgtctgaaa aacaccgggc tgcggcaatg tctgtcccgc catctgtcca atccaggcag
    12181 caggccgatc ggcagagata acaactaaag gtatattctg ataatacgct tctgccacag
    12241 caggatgaag attgagcaac gctgtaccgg aagtacagca aacggcagca ggatgcccgc
    12301 cattcagcgc aagaccaatc gcaaaataac cggcactccg ttcatccgtc atagcataac
    12361 aagtaaaacc cggatgagta gacagcgtat gcacaatagg tgcattacgg ctaccgggac
    12421 ataacactac tttcgtaatt ccatgcgcct caagcagcgc gaccaactgg agtatatttt
    12481 tcttgtccga atacatattg atagtgatta gcttgttagt gattcatcat tattggagca
    12541 gatacaagaa tacgcctcat ggtctgcaat ttcttttccg tttcctgcca ttcatcattc
    12601 aactctgaag aggctaacaa tccgccaccg gcatacagtg tcaattgctc gtcttcaatg
    12661 tgcatgcaac gcagattcac atacaaatct gtgcgtccct ccggatcgag ccaaccgata
    12721 aaaccggaat aatacttacg atcgtaccct tcattttcca aaatgaaccg gtaggcttct
    12781 tctttaggca gtccgcacac ggcaggagtc ggatgcagga ctttcagaag gtctcccaga
    12841 tttttattat ctttcaaaga gaaatggaaa tcagttttca gatgtgacaa ggcaccggca
    12901 taagccggat aaggtccgct ctctgtggag cgaatgccca gcgaaagaag ctgccgacgg
    12961 atataggacg ccacataatc ctgctcctga cggtttttgt catcccatac ttgcggaagt
    13021 ttaccattct gcaaaggttg agttcctgcc agggcaactg tgttccattc atttttttcg
    13081 cccgacaata taatttcggg agtacttccc agccacacgc ccgtctgagg agtataacac
    13141 agatagatat aggaatgaat ataacgttga caagctgcac gaaaaacagc tgaaggggaa
    13201 aactccggat tctttccaat agtgagacta cgggaaagca ccagtttatc aaaggtagca
    13261 tcacgcaagg cttcaataaa tgtatgaaaa caggtcgcat acttcccagt acaaagggta
    13321 tgaaaagatt cctccggata actttgcaag ccctgctctt cctctgccac gatttccata
    13381 ggcaacggtt gtccagtcct gtcggactgt atcaacacaa tcggacatga cttatctaca
    13441 cggaacggag caatcacaaa tcctctttgt ccattcagtt ctttcaaatc gaaaatcagg
    13501 cggacagctc cgacatcttc tgtcaacaga cgaggatact tctccccggg aacacgataa
    13561 acagcaaagg gctgtttccg ctgaataagt gcatcaatag ttgtcaagtt acttttttcg
    13621 tcaatcatct ttttttcatc acactgttga ccacccgtat agaggacacc agtttattgg
    13681 ttgaagtaaa aacgtccaca ttccatacat gggaggaacg tcctttgtgt acaatcgtcg
    13741 ctactgcacg tactgtatca ccttcgtgcg cagaagatat atgatttccg ctgacctgca
    13801 ttcctaccac aatttcatcc ggctgacaga gaatcatcga gccgagtccg gcaactgttt
    13861 ctcccaatgc aagcgtagct ccaccgtgca aaataccgaa cggctgacgg gtacggtgat
    13921 ctaccggcat cgtcgcctct acacggtctt cgtcggcata tgtatattgg atacccagat
    13981 tacccatcaa tgcgtgacgc gcctgtgcat tcaactggtc caaaggaatc tctgcagcgc
    14041 gaacttccgc tattatcgcc ttttcgacag ccagagccac tccgtcttcc tcattggaag
    14101 ctgtcacata atccgcacag acctttaccg aatcctgcga atgccccatc gccactccca
    14161 gtcctgccag ctgaatcatc gttacatcgc acacaccgtc tcctatagcg atgacttctt
    14221 cacgcttcac attcagttct tccaataaag ctcccaatgt gttggcttta tcaatcgcac
    14281 acggcactac ttccagaaaa taaggttcgg aacggaaaac atccaaagct ccgttcaacc
    14341 gtctcttcca gtgtccttcc agactaacca acgcttcctc gtcatcgctg acaagcatac
    14401 acttacacgg agcaaagtca attgctacag aaaattcctc ttccttgatc actttcaaat
    14461 tattcaagcg agcttcattc tggatatgtt cattctccgg agtgtcagta atgatcgtat
    14521 catcatggta agtgaacagt gcgaaattat tttttcttgc cttcttttcc agataaggca
    14581 acatttccgg attaatcctc cgctcaaaca gtatttctcc gttttgagca ttaattatct
    14641 ggcaaccatt ataagaaagg atataacctc cataatttcc gagttctagg gatttggcta
    14701 aaggcatcag accgtaagtc ggtcggccgg atgccaacac gatacgtact cccatctgct
    14761 gaactttcag caaagcagcc aatgtacgtt tactaatttc ttttgcatca ttgagaagcg
    14821 ttccgtctac atcaagaact aataatttat acttcatgga cacacgattt tgatttagat
    14881 tacaaaggta ggaaattgag tgaacgactg aaagcggaaa gagataaaaa ttactttaat
    14941 ttcactcttt cagatgcatt tccaaataat cacgaaggat tcgggcatga ttataaaccg
    15001 gttctttgga tgcataaagc aaagtgatca ccagatgagg tttgataaga gtcagaaaat
    15061 cggcaacagc ttgagaagct tccagttcct tctgatacat tacgacaaaa tcattccagt
    15121 gccccggaat atcttcatga aaccatctgc gcagtgctgc ggaaggcgtt atatcttttg
    15181 cccagtaatc atatttcaac cattcttttt tgattccacg tggccagagt ttatctacca
    15241 gcacccgata tccgtcggtc tctgaaaagt cttcgtacac tcgctttatc ctaacttgca
    15301 ccatttccgt ttatatttag ttatcataag aataaaccga taaaacggaa aattgtttat
    15361 cgaaaaagcc aaaatcaacc taaggattcc tgcgcttttt taaattcgta aggagtcata
    15421 ccagtctttt tcttgaacat actgtacaga ataggcgtac tattaaatcc ggcttcatca
    15481 gctatcgcac gaatggtata attgggatgt tgcttcaata actgaatcgc atagttaata
    15541 cgaagttcat taatataccc gttgaaatta gttccggtgt tttccttgat catccgggcg
    15601 aaacgcgcat tattcaaatg tacaatctga gccagatcct ctctcgacaa ttccggagac
    15661 agatataact gatcctgaac aacaatacga ttcagttctt tgaaaatttt cttattctca
    15721 tcctcttcct ccctactctc cactacttca tccggagata aatcgtcttt ttcggaaaag
    15781 ccagtttccg gttccaagtc caatggaaca gctatcggat cttccgcatc tccatctatg
    15841 aataattgtt tgttctctac ttttccagcc agtttctcat tgataaactt tgccagcatt
    15901 ttgtttttat atttaacaat aatcgtatga cgccaaatcc gccatagcac aaataaaatg
    15961 agacaagtga cacatcccaa aaaagcaagt gatatgtttc tgattcttaa ctgtaaagtc
    16021 tgttcggcaa tatattcttc ctgctcgtca gctttatgaa tagcatttaa ttccaaagcc
    16081 gcattctgtt tatccttgct gttaatacca tcaataatag aaataataga ctcacgtaat
    16141 gctgctactt tttcaaaatc cttcaagcct ttataagctt tcacctcttt ctgaaggata
    16201 ctaatatact gcaagttgac agtatcctgc tcttgcatca atttcttaaa atcctgacat
    16261 tgatcaacga ctttctgata ttgtttagac actagcagat aaggtatcgc ataggttttt
    16321 ccatccggtg tctgtgaatt ctctgttgac aaatattgtt gataatattt ttccgcctga
    16381 tcatactttc cttccagata gcagatatac gacatttttg catacaagta agtatattgc
    16441 agatcaagaa agccttttgt tttttccggt aatttagcta tatctttaag tagcttttcg
    16501 cgcttcaacc caacctccaa tgcttcttta ctacgggaat cattgagcag ataatccatt
    16561 ttcatcccat aaaagtatga aagcatagcc atttccaatt tggaacttgt accttgaagc
    16621 aatttgatag ctttgtcaaa atagtcatat gcctcctctt tgaaagacaa ttgccattta
    16681 ttttcaccaa tgcaaaacaa cagcttactt tcagcccctt tatccttttc tttttgtgct
    16741 agcttgatac catcaagagc atacctcata ctctctttat ggtcactcat aagcactgct
    16801 aattctgcca ggtcgacagt catggtcaac aagtgcttag gatctttctg agaaacggaa
    16861 tccagcaaat aagacttttt ggcatacaaa aaagccagtt tagtcatata catattacga
    16921 taaaccctgc tgcgtaattc atgtataata cgcagaggga tagtcttctt actttcagct
    16981 ccatccaaca aacttaaagc ccgttcaggt tctgccatat aaattcgact tatatactca
    17041 ctggtatata gcgaatcatt ctctatagtt ttgtcggcga aaaggagctg gttaaacaca
    17101 aacaaaaaca aacaaaaaca aataaccgag cgaatacttt tcattataat cccaatgatt
    17161 ttactcccca aaagtaaaac atagtttcat aaaatgcaag aattgaacat atttgaatga
    17221 actaaaataa gaaaagttag tgattataaa agtcaagagc catcaagtct tccccaccaa
    17281 ccacatacaa taaaatacta aaaatcaagc atatgtcaca tacataaaac aaaacatctc
    17341 aacatacaaa taaactgccg attctattaa ggaatctgca taagatcaga gcagcacatg
    17401 aaaaatcgaa ccgaccagtc taaataaaca ccagacaatt attaacccgc cacactcatc
    17461 agagcaaaac agcacaaaaa cagaaaatca aaaaagagaa acacatactg taataagaaa
    17521 gattataatc ccaacgcttt atcaaaccgt tgctccatac atgcactcaa atccgtcgtt
    17581 acaaactttc ctttatagaa aagagaaaag atagtagcag gtgtaggtgc attttgtgct
    17641 tgtgccatcg tttccaatct gactatcttc aatggaatac ctttgttctc agtcacaccc
    17701 actaaagaat tacggacatg aaactctgca aacggacaac gatgtgtata ataaacgact
    17761 acaccttctt tttcctcaca ttctccactt gatactgttc cattgaatga cggatcagga
    17821 gctgccggat ttatcttcaa agccaaaaga ctgaaaccat agggtagttt ttctatcgtc
    17881 tcaaacccct gacgtaataa ccatttcgca tcacccataa aatgaaattt agaggtaccg
    17941 accacagtca ccaagccatc cctaccctgt gctttggcat cctcgacagc agactgtaat
    18001 agtgctttgc catgcccgca tcctttatat tttcctgaaa cccaaaaaca gtttatcatt
    18061 aaatagttag gtgcattaac cggaacccaa gctttttcgg caggcccata ttctataaat
    18121 acttttgcac gttcgtcaag ccgtctgaaa acatagccat tctcaaactc atttttcagc
    18181 catgtctttt tcaactcata gctatccttg catttcttat cggagaaagc acagcaaata
    18241 tgttcttttt cgatattctc tttagtcaga gtgatatact tcgcttccat aatattctgt
    18301 ttattagtat ataaattccg gttgtccatt ttaactacag caaagataca caatcgaaag
    18361 taataaaaca ttgtccagtc tcgtcaaaat gacacagtag tacggattaa agttcggaaa
    18421 acagataagt aaataaacct gagtgacaaa cttatcaaag aacttattga ccactctgtg
    18481 gaagaagtga tcaaaaaact ccctaagaaa aaacaggagg aatatcgcac aatgatttaa
    18541 cataaagcgt gaaaccgctg actggtaacc atacaaatat ccggctttgc tgcaattcac
    18601 aatagtaaag ccggatattt aactgttaaa agcatatatc ccatatacca caagcacttt
    18661 ccaatgctac tagtgaagcg gcatatcctt tcattgtttc cagatactcc tgttgcactt
    18721 cattataagt acgctgggca accagtacat caagaatact cgtttctccc cgtttgtatt
    18781 tatataccat tccgtcgagc accttctgcg agtcttcaag tacaccggct ttatattgag
    18841 ctatcttttt cttttcagcc tcatagttga accaggcctg ggttatctct gcctgtatct
    18901 gcaattccat atctctttcc attatctccg attgggcaat ccgaaacttt gcagctttta
    18961 cagctccttt atttatattc gagaatgtca gaggaacaga tacaccggca gtagcagaac
    19021 gggacggagg aagaaagccg ttccagtttc tttcataaga aacagatact ccgatatcgg
    19081 gtctgcgttc cgctctcgtc agtttatatt cccgggtagt aacttcagta cttttttgag
    19141 caacaagcag gtcgatgcga ttatccagtc ccgctttgac caaatcagac agagcaaagt
    19201 ccctgcttag ctcttcccaa tttcccaaag ggatatgaag cgtatcagca ctcatcccca
    19261 tgtgtttatt caacaaaacc aaagcggaat gataagccgc ctcctgactg taaacagtat
    19321 taagcaaggt gacagcttcc agttttgact gccggacatc attctccgta atctctcccg
    19381 aaacataacg taaactatct gactgactca gctgatacat atactcataa gaacttttct
    19441 gtacttcaag taattcgcgc tgaagaattg cttctagaaa aaggtcggca gcctccgccc
    19501 tcaaatcctg aaagccctgt tgcaggacca gtttctccaa ttctgcctga gtccgcgcca
    19561 acttaatacg tgctcccctt ttatttccca tttctaatga ataggaaact cccaacgaga
    19621 aagtctcatt acctgcttca aattccaact ccggatccgg aaagattttc cgggcaatta
    19681 cttccgcatc agcaatactc acattgagtt tttcggctaa ataactcagg ttctttttcg
    19741 ctacccgatt cagatattct tcgaaagaaa tagactgccc cagctttatt tcaggcattt
    19801 gcgcaaaagc cggaatgagt acggcttcca ccattaacag caagagcact atattatatc
    19861 gtatattctt tttcatcgtt cttcttttta tttaaaacat tgttctcaac cagataatag
    19921 aaagccggaa gcagaaacat agagataagg gttgaaaaca tcaatccata cacaatcact
    19981 gttgccagcg gacgctgtac gtcactaccg attccggttg ccaacgaagc cgggaaaagt
    20041 ccgagtatcg tagtgatcga agtcatcaga ataggtcgga aacgctggcg tgccccttct
    20101 atgaccgatt tccggagttc cattcctccc ctgcgcagcc cattgacctg cgataccatg
    20161 ataattccat tttgtatgga aagcccgaac atcgctataa atcctacggc agaagataca
    20221 ttcagcgtca taccacgcac attaagagca agcatacctc cgaaaagtgc cagaggaaca
    20281 atagccaata ccagtcctgc ctgccggaac ttcccgaacg tgacataaag cagtataaac
    20341 atccctgtca gtgtcagcgg tataatgaca gcaagacgtg tataagcccg tttttgattt
    20401 tcgaaggccc ctccccattt gatggtatat ttattcttgt cataatgtac tttctcattg
    20461 atcgtattct gggcttcatt cagaaaagat gtcaggtcac gaccgcgcaa attcagcttt
    20521 accgtcaaat ggcgtctgtt catttccctg gtaatcgtac tttcgccgac actcaatctg
    20581 acatcggcaa cctgagaaag aggtatcttt gcaccggtgg aagaagtcaa cataagtccg
    20641 gctattttct ccggagtatt ccgcgcttcc tctttatact tacaggtgat gccatactgg
    20701 cggtcaccct gataaagttg tgcgatagct ttacctccga cagccacttc aatcagatcc
    20761 gctacatcgg atacatttaa tccgtaacgg gctatggcat cacgattcat actgatctgt
    20821 aactgtggca agggtggttc ctgatcaata tccagatcaa cagcccctcg cacagttcct
    20881 aatgccctgg ttatttcttc ggcaatacga cgtgtttcac gaaaatcttc gccatatact
    20941 ttcaccacca gttcactatg ggccccggct atcttatcca tcaccccgtc tatcataggt
    21001 tggctaaatc ctactttaaa accgggaagt aacttatatt cttcttccag ttcatgaatc
    21061 aaatcctttt tagtttttcc tttcggccat tcatcataag gcttaatacc gatggacact
    21121 tcaaaatgtg aaggggtgaa cggatcagtt ccgtcgtcat tccttcccgc ctgtaccata
    21181 atataagtta cttcggaata cttcatcgta cgggcacgca aagtatcgga taactcccgt
    21241 gacttttcta cggaaattcc gggtggcaga ttaacctgta accatatcga accttcatct
    21301 agctccggaa ggaagtcttt tcctacgaca acactcaaca cgatccccgc tgtcagaatc
    21361 agtcctgatg gaatgatggc ttttaaggga gcttccagaa atcttgtaat ggtacgaatg
    21421 tatttatcct ttagtctgtc cagccattta ttcttatata ttttatgtgg tttacgatag
    21481 attgcatagg caagtcccgg aatcaataag agcgcaacca acagtgctcc aatcattgca
    21541 tagctcatcg taaatgccat tggagtaaaa agtttgcgtt caacacgttc aaaggcaaac
    21601 agcggaaggt atgccgtaat aatgacaatg gttgagaaaa gaataggccg acccacttct
    21661 ttggcgcgtt gcgccatgct tttttcttcg agatattgtt tgggattatc ctcacgtttc
    21721 ttaaggatcg tttccagcat aacgatagca ccgtccacaa taataccgaa atcaatagca
    21781 ccaagcgaca gaaggttagc cggaatatcc gtcagatgca taagaataaa agcgataagc
    21841 aatgacacag gaatcgttat agataccaat aatgcaccac gccagttgcc tagaaacaga
    21901 ataagcacaa gaaacaccaa agccataccc atcagcaagg tatgggatac ggtactcaaa
    21961 gtagtatcca ctaagttggt acgatccaaa aaagtatgta tcctcactcc ttccggcaat
    22021 gtctcattat ttaactcatc aactgccaca tgaatatctt ccagtacttt agacggattc
    22081 tcatgtttca gaaggagtac gattccttcc agactctcag agtagttgcg ggtacggtcc
    22141 gtatatccca gcactccctt tctttcaaga tttccatact tcaaagaacc tatatcattc
    22201 agaaagacag gaactccgga agtagtactc actacaatat gtcccaaatc gtccagattt
    22261 ccgattaatc caattccccg taccacataa cccaagtcac cacgattcaa cacgcttccc
    22321 cccacattgg cattgttatt ctcaatggct tcaacaacct ggctgagaga taaattatat
    22381 tgttccagtt tggacggatc tacttcaacc tggaactgag tagtgatccc accgaaattg
    22441 gttacatcag ccactcccga cacttccttg atacggggaa taattaccca gttctgaagg
    22501 tcggttaatt cgcgtaatga gtgctggtca ctttctatga tataacggta cacttctcct
    22561 acgggagatg tcagcggatc aagtcccgga acagctccat aaggcagttc tacttcattc
    22621 aatctttcct gtacgcgctg gcggctccag tagtcctctg tcccgtcctt aaagacaatg
    22681 gtaatcattg acagcccgaa tgtactctta ctccgcatga cgtgcatacc gggcagccca
    22741 ttaatagcgc gttccaaagg aatggttatc tgctgttcca cttcctccgc agccagtccg
    22801 ggaacttgag tgaccacctg ggaagtgaca tctgcaatat ccggatatgc ttctatcgaa
    22861 agctgtttcc atgagtaata tccaaagata cacatcatca caaacaggca aagcattacc
    22921 catctttttt gtataattga aagcattaat tccttcttca taaattctta ctttaaataa
    22981 tatcctcctt cactgattat cttatctccg ggacgcaatc cttcgctgat caccgctatt
    23041 ccgttttctg ttgtctccac tgtcaccgac gtccgtacga aaaccaacgg agcaatctgc
    23101 acaaatacat agctatcctt ttcgccctgc agtaacgctt tctccgggat ttgaatttgt
    23161 ccgaccggaa cactcagaaa gtggacagta gtgtacatcc ccagcttcag atgtccgttc
    23221 aaattatcac agaccgaaag tacctgaatg gaccgggttt cctcgtctac ctcctcctct
    23281 acatgataca cattgccttt aataaccgta ccgggcaatg ccgaaatttc aatatccaga
    23341 ctactgcctt catttataaa ccggatatct ttctccttta cctgagccgc aatccatacc
    23401 ttagacaggt cggcaacaat agctatcggt tcggtatcgt ctttcagata ttgccctgtt
    23461 acgatgttat cctttatcac ttccccggga ataggagaac gaacaatcat cggttgcccc
    23521 aatatcattt ccgccggatt gtccacctga tatacccgca atgcggcaga ggcgttttca
    23581 aactccttat ctgctatcaa taaagcattc tgggcttctt ccagttctct ttgcgaactg
    23641 acaccattcc ttatcagatc ttctttgcgt ttcaaatctt ttttagcaag ttccctggac
    23701 gaaagtgcct gaaagtattc cttttgtgca gaagtaaagt cgggggaact gatttcaaat
    23761 aaaggtgttc cctgacgtac cgactgtccg atacgcacat aagattttgt gactctccct
    23821 gcaaatggag gagcaacata agcataacgg ggaggaatgg gacgcaccac accggacgtt
    23881 atcaccttct tggaataggg tttcagttca gacactgata ctttgatctt ttcaagtaaa
    23941 agaggatctg caatatagac cgtgtcacct tgtatacgat agccactttt ttgctctgat
    24001 tcctgtttat ccccgcatgc ggtaaaaaac aacacactgc caataataaa tgtgtgtaac
    24061 tctctcttca tcatcataat taaacataag ttaagttagt aaccggattt ccgggcacaa
    24121 agatagacgg ctcccttcgg agagcctgtt agagaatagt tagaatccta ttagaatctt
    24181 attagagtaa ataaagattt cttcttaaaa cagcagcttt gttgttagag agtacgcaca
    24241 aataaggggt tgactaaaaa gccaacccct caacggatga tattccggta tttttatcgt
    24301 aagccgaaaa gttcttattc tttcacacaa cgtatacttt gagcaaaacc ttgatatgac
    24361 aatctgaaat tatgagaatt atatgcagac tcaagcgacc aggctccata acgtattctc
    24421 ctgtcataag gtggattctg caattctgat ctcatataag gaggacctac acttgccgac
    24481 caatagtatc cggtactacc cctactttcc aaagcaccac ttgtgttatt cagacgaccg
    24541 gctgacggaa aaaagacaga tgcattcgtt ccggaatcgg gattaaaata caatactccc
    24601 tgataagcaa cattactatt tcctaatgat acgccatagt ttccattcga agcctctttt
    24661 atcggacgtc tgtcgaaaaa tccgtccgaa taaaatgtat aagttgttcc ttttagttgt
    24721 ttccgggcaa gcatatcttt gtttgctccg taaggatatg tcccaggacc tgtattacca
    24781 gttccaccaa aaggagtagt aaaagctgta gcgtagtctg cacttgaagc cgcatttcct
    24841 gcaaaaggta cattaaa
//
