LOCUS       c00161_gnlPro..        13267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNNFBMAA_161.
ACCESSION   c00161_gnlPro..
VERSION     c00161_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:06:09
            Original ID  :: gnl|Prokka|PNNFBMAA_161
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13267
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[308:3267]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      309..3267
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             309..2537
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg161_1"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2542..3267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg161_2"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3500..4762)
                     /locus_tag="ctg161_3"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATTPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTMSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVVGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4814..5362)
                     /locus_tag="ctg161_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5550..6302
                     /locus_tag="ctg161_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6407..7405)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg161_6"
                     /sec_met_domain="LysR_substrate (E-value: 8.4e-47,
                     bitscore: 150.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.8e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQRELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7475..7948
                     /locus_tag="ctg161_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8052..9050)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg161_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.1e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9105..10373)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg161_9"
                     /sec_met_domain="MFS_1 (E-value: 2e-12, bitscore: 38.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIAMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10623..11636)
                     /locus_tag="ctg161_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQLVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11659..12795)
                     /locus_tag="ctg161_11"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 tcgcagtaca acggttttca agaccgccgc aatcgaccac tctgccacct ctccagaact
       61 acggttaagt agtgcttttc tcttaaagcg ctgcaaaggt acgaatcatt ttttaacttg
      121 caaattattc cgcaaaaaaa tattagaaaa gtatatttgg aagtaataac tgctatctgg
      181 cttctcccca taaataggta tttttatgct attcaacata aaataggacc cttttatata
      241 cctaaaccga aaaaaggttg taaatttgcg cgctctaaag gataactaac cactaactga
      301 ttaattttat ggaactgaat aagaccttta aagatggact ttggagcaaa gaaatcaatg
      361 taagggattt cgttagtaac aacatcactc cttatgaagg ggatgcttct ttcctgcaag
      421 gacctaccga acgcaccaaa gctgtctgga atcactgtct caaagctctc gaagaagaga
      481 gaaacaataa tggtattcgt gcactcgact acacaactgt atctactata acctctcacc
      541 ctgccggcta catcgataaa gagaacgaac tgatcgtcgg actacagacc gatcaggtgt
      601 taaaacgtgc catcaaaccg tttggcggaa tcaatgtggt tatgaaagct tgccgtgaaa
      661 acggagtgga agtagatgac agagttaagg atatcttcac tcactatcgc aagactcaca
      721 atgatggggt attcgatgtg tataccgaag aaattcgttc gttccgttca ttgggattcc
      781 ttaccggact tcccgacaac tatgcacgcg gacgtatcat cggtgattat cgccgcctgg
      841 ctctctatgg tcttgaccgt ctgatagaag ctaaaaaaga agatctgcat aatctgacag
      901 gtcctatgac tgaagcccgc attcgtcttc gcgaagaagt agccgagcaa atcaaggccc
      961 tgaaagagat taaagtattg ggcgaatatt atggtttgga tctgagccga ccggcatata
     1021 ccgcacagga agctgtacaa tgggtgtata tggcttatct ggctgccgta aaagagcagg
     1081 atggtgctgc catgtcactg ggtaatgtat cttcattcct cgacatctat cttgaatatg
     1141 aattaagcca gggtacgata accgaaacat tcgctcagga actgatcgac caattcgtta
     1201 tcaaactccg tatggtacgc cacttgcgta tgcagtcgta caacgatatt tttgcgggtg
     1261 atcccacatg ggtgaccgaa tctatcggtg gacgtttcaa tgatggacgt accaaagtta
     1321 ctaaaacttc tttccgcttc ttgcagacac tttataactt aggcccgtca ccggaaccta
     1381 acatgactgt actatggagc cctgagttac ccgaaggttt caaagcattc tgtgcacaag
     1441 tatctatcga cacttcttcc gtacaatacg aaaacgacga cctgatgcgt gaagtccgtc
     1501 aatcggatga ctacggaatc gcttgttgtg tttcatatca ggaaatcgga aagcagattc
     1561 agttcttcgg cgcacgtgcc aaccttgcca aagccctgct actggctatc aacggaggac
     1621 gttgcgaaaa tacaggtaca gttatggtaa aagacatccc tgtattgacc ggtgaaacac
     1681 tgaagttcga agaagtaatg gccaactata agaaagtatt gatacaaatt gcacgtgtat
     1741 acaacgaagc aatgaatatc atacattaca tgcacgataa gtattactac gaaaaggcgc
     1801 agatggcttt cgtggatact gatccccgca ttaacctcgc ttatggtgta gccggacttt
     1861 caatcgccat cgattcactg tccgccatca aatatgcaca tgtgaaagcc cgtcgcaacg
     1921 acatcggact gacggaggga ttcgatatcg aaggtgcttt cccttgtttc ggtaatgacg
     1981 atgaccgtgt agaccacctg ggtgtggacc tggtatattt ctttagcgaa gaattaaaga
     2041 aactccccgt atataagaat gcccgtccta ccctttcgct gctgactatc acttcgaacg
     2101 taatgtatgg caagaagacc ggtgccactc ctgacggacg cgccaaaggc attgcctttg
     2161 ctcccggtgc caaccccatg cacggacgtg ataaaaatgg tgcaatcgcc tcactgagtt
     2221 ctgtagccaa gttgcgttat cgcgactcac aggatggtat cagcaataca ttctcaatcg
     2281 ttcccaaatc attgggagca acacaagaag accgtatcga caatctggtg accatgatgg
     2341 acggatattt tacaaaaggc gcacaccacc tgaacgtaaa cgtgctgaac cgggaaatgt
     2401 tgcaggatgc gatggaacat cccgaaaagt atccgcaact gactatccgt gtctcaggat
     2461 atgccgttaa tttcgtgaaa ttgagccgcg aacatcagtt ggaagtaatc agccgcagtt
     2521 tccacgaaag aatgtaattg aatgataaac gtacactcat acgagtcaat gggaacattc
     2581 gacgggccgg gtctccggct cgtcgttttc cttcaagggt gtaacttccg ttgcctctat
     2641 tgtgccaatc cggacacaat tgaagccaaa ggagggacag caaccgaccc tgaggaaata
     2701 gttcgcatgg ccgtcagtca gaaagctttc ttcggtaaaa agggaggtat caccttttcc
     2761 ggcggagagc ctacttttca agcaaaatcg cttatcccac tttttaaaag actaaaggaa
     2821 gcaggaatcc atatttgcct tgataccaat ggcgggctat ggaacaatga tgtagaggaa
     2881 ctattggaat tgactgatct ggttttatta gatatcaaag aatttaatcc ggaacatcat
     2941 cagtctttaa ccggaagaag caacgagcag accctgaaaa ccgcagcctg gcttgaaacc
     3001 aatcataaac cattctggtt gcgatacgta ttagtgcccg gctacagtga cttcgaagac
     3061 gatatccggc aactgggaga gcatcttgga acgtaccaga tgattcagcg tgtagaaata
     3121 ttgccttacc acaccttggg tgttcacaaa tatgaagcaa tgaacaaaga atatatgctg
     3181 aaaggagtga aagagaatac tccagagcag atagaaaagg ctgagaaact attcaggcaa
     3241 tatttccaga ccgtacaagt aaattgactt atataagtgt cgaaattcgt attcaccaca
     3301 gattacacga atttacacaa ataaagattc attggcaatc aacagattaa gttcactctg
     3361 cggtgaatta tgacgattgc acttatttat aattttgtaa gtcacgatat aaaagtctcc
     3421 ctgttcttgc cttaattcat tacaatacaa ggcaagaaca gggagataat gtaaccggca
     3481 tattttttgc catcctactt taataagtga atcgcaatcc tgcctgcaag ttaaagttac
     3541 aaggcctttc ttttcggatg gtttgtactt tggagccatc atcaaagaaa tacgaaactc
     3601 ccggttccac atataggccg acatgatctg tcgcattgaa ttgcgctccc acggcaccga
     3661 ctacagaaaa ttgcaaaggc ttcacattca ccttatcatc cgccaacttt ccataaacac
     3721 acttttcaac cattcctccg gcagatacat agagtgtaaa atatttcttt tccagaaaat
     3781 tccagtttcc acgtacagga atacctatat aatgcaattt ctgactctgc atcttggtat
     3841 ccccctgccg tttgatgtca gaagacaaca acgtataagt caatcccgtc tctacagaga
     3901 aacctttggg aagagactta cgtacagaca gtccgaagct aaccggctga tgatgttcat
     3961 aatccaccac ggcagttgta ttggacttca ggtaagggac tccttcttca aatataactt
     4021 cctgatcggc aggaatactc acagctccat tcatgatcgt catcaagtcg accctgttag
     4081 tcatcggacg gggcgcaaaa ttttcggaac catttgtcgg aagtccacct ccattaccga
     4141 tacccactcc catcgaccat ttaccaccac gtttagcaga agagtctccg ataggcaact
     4201 gatacttgtc tttaccggac ggtcgccgcg cttctttcct ctttggaggc tgcgccgtcg
     4261 cactttcttt tttctcgatt gcagcaattg cttcctgttg cggctcagat ctcttttcct
     4321 ccgtcactgc ctccggtcgc ttctctacca gggaggatac ctccggaaca atcaccggat
     4381 cagtattctt tgccaaatag cccgaaacag ggttaatact catcgttcct accggcttaa
     4441 ctggttcgga tacagctacc tgtacatccg gcaaggcagg ttccggcaat acatccgggt
     4501 tgacagccag tgaaggagtc gttgcataac ggatttcatc agctaccgga ctattcagaa
     4561 aatacaaact gacagcagtc gttaccacca ataccacagc tgccgcagca accgcccacc
     4621 ggcgatacgg atatattcgt ttttcggtta caggcatcag ttccctttcc agtcgttccc
     4681 aaccggaagc aggcatcggc tccgaataat cttcgagctt atccttgaat gctttaatcc
     4741 atttttcgtc ttctttcatc attctatttc atttttgaaa tccaaggttc acctcagtat
     4801 ctgtaaatac atgtcaacca ttggtcacca accattcttt cactttcttt gccaatacac
     4861 tttttgcgcg aaaaagctgt gaggcagaag atttttcatt aatccccaac atctgtgcga
     4921 tttccttgtg cgacttatct tcaaaggtgt ataaattgaa tacggtacga tatccggcgg
     4981 ggagttcatt aataaattgc atcagcactt tctgtggtat tgcttcaaca gccgaagcat
     5041 ccggttcttc atacgtttcg ggaacttcat ccagtgccgt ggtctggttc atcacgtcgt
     5101 tctttcttaa gaactgtaaa gccgtattca ccattacacg ctccatccat gctctcagag
     5161 agccttcacc ccgccaggta aacttgtcga aggagtcgaa aatcttcagg aaaccgtcgt
     5221 gtaccaagtc ttgtgccatg tccctgtctc cggcataacg aagacagaca ccaagcatgc
     5281 gccctgcgta ctgctcataa agttctttgc gggcacgatt atctccctgc ctgcaacgtt
     5341 ccgacagctc taattcattc attctcctaa acacgtgttt accttataaa tgcagcaaag
     5401 atagaaatac tgcacagaga gaacaactct tttatcactt ttgtttcttt aacattttag
     5461 gatgcaatat ttcatcactt cctgcatttt ctcaatacaa taaagaataa atctcaatgg
     5521 ataaatagga taaaaccaac aagaaactta tgaagaaatt taatttaata acttttgccg
     5581 tcatcctgat gttattgccc attttacagt catgtctgga cgatgccaac aacgacgagt
     5641 gggtcacttg tcctccgggt ggaatattag ccatcggcac aatgaagatt cccaatgcgg
     5701 acactccaag ggactttttc attgcgttgg acaatggaga caatgtactt ccggcagata
     5761 cggccgatat acgcaacagg aaatacactg ttgcagaagg tcaaagagtc ttcgttggct
     5821 atctgcagat gggaaaagag aagcccggat atgagaacgg taaaatattc acgatagaag
     5881 atatattgac gaaagagatc atcccactga cggaagctac agcagacagc attggagacg
     5941 accgtatcaa cgtcacagcg catgcactta cgaaagatta tctgaccatc gaatatcaat
     6001 atctgggcag catgaatgaa aataaaaaac acatgctgaa cttggtacaa aacgaaataa
     6061 caggtcccat aaaagatgac ggatatatct atctggagtt ccggcataat gcctttaatg
     6121 actcccccaa tcaattgggt tcgagccttg tttctttcaa gctggatagt atagccgagc
     6181 aattggcgac agccaaagga ataaaactcc gtgtgaacac catttatgac aatatacagt
     6241 atgtcacaat agatatcaac gaagacaaaa atttaaaaat aaaatcattt cattctcaat
     6301 aaaacaacaa gaaacaccta cacaatcagg caaaacgagt aataattctg atacataaaa
     6361 gaaataaggc ggcgatgttt gtgaaaatat cgccgtcgtt tttatattat accagacact
     6421 gaacggcctg cagggtaagc atctccttgg gaaccgccgc ctgaatctcc tctttcaaaa
     6481 cctgcagcag actggtgcgg atgaagtctt tccgggtcac caggacaatc tgacgggtag
     6541 gccgcgggat agcaaacgga cggaccagtt ctctctgctc ttcgctcaat tgcatcactg
     6601 ccagttcggg aataaacgta atccccttac cactctccac catatgcata aaggtttcca
     6661 tactacccag ccgatacgcc atttggctga tcttaaccgc ttccatctga caaaaacgaa
     6721 ccaactgatc gcggaagcaa tgcccttcgt caagaagcca aagccgttcc cctgtcacat
     6781 cggacgtacg aatcacatcg tgcttgaaca acggttcctt ctttgagaca tagcccagga
     6841 attgctcgta aaataaggtc tcttccgtta atgcggcatc atccagcatg ctggcaatga
     6901 tagcagcatc cgcttcaccg gtcagcagag ccttgcgaat gtcgggcgtc ttcatctcca
     6961 tcacccgtat atcaagatct gggtatttct ccatcagttg cggaaagaaa cggggcagaa
     7021 gataaggtgc aatcgtcggt aacactgcca atcggaatgt acccgacagg gagtgctgtt
     7081 cttcgctgat gatctccttg acacagataa cttccgaaag aatcttacgg gcctgttcca
     7141 gcactttctt accaatggca gtagggcaaa ccggtgtcat gctacggtcg aacagtttca
     7201 cccccaattc gtcttccagc ttttggatca ttgcactcaa agtaggttgc gtcacccggc
     7261 aatactcggc agctttagca aaatgccgga actggtccac agccagaata tattccaatt
     7321 gttgtatagt catcgttctc tgatttatta aagatataga atctatcaat gcaaagatag
     7381 aaattttcag tttgacacga atcattttgt gccgtatctt tgttccagat aaaaagaaga
     7441 aatatagtat taactcaaaa aaaacaatat cattatgaag actttaaatt atacacattt
     7501 ggaagaaaaa ggagctaaca ccatcgtact gtcattacag caactgcttg ccgattttca
     7561 gattcattat gcaaacctga gaggatttca ctggaacatc aaaggacacg gtttcttcgt
     7621 actgcacagc aagtttgaag atttatataa cggagccgcc gaaaaggtgg acgaaatagc
     7681 cgaacgtata ctgatgctgg gaggaactcc cgccaataaa tacagtgact atctgaagat
     7741 ggcgcagatc aaggaagtgg acggagtgaa taaggccgac gacgctctga atcatattct
     7801 cgaaacttac gggcatctga ttgcggaaga acgtaaaatc ctgtctctcg cctcttcaca
     7861 caacgacgaa gtaacagtgg ccatgatgag cgactacctg aaagaacagg aaaagatggt
     7921 ttggatgctg actgcataca acggataaca gccgaaaggg tgtagccatc tgaccgaaaa
     7981 ggtgtagcca tacaagcaaa agggtgtagc catcccggcg ggatagctac accctttctg
     8041 ttttattcga ttcagatgat acttgtacgt ttggtaaatt caataatctc cggaatgtat
     8101 ccgaatgcga gcccggtcac tgtatccgca cacccataat agatggcaat ccgtccggtc
     8161 tccgaatcat gaagcgccgc gcatgggaaa cagacattag gcacatcacc catacattcg
     8221 taatccttct gaggtgaaat cagataaggc cccgaacgga attttacttt ccagggctga
     8281 tcgatgtcaa gcagtgccga accaaaacta tacacaaaac cgttgcagga agccaataca
     8341 ccatgataga tcagtaacca gccttccgag gtttcaatcg ggataggccc tgcaccgatc
     8401 ttggtacact gccaggcact gtcttcgaac ggagccggcg acataacatg acgatgacgt
     8461 ccccaaaact ccatatcggg agactcgcta tagaaaatat ctccaaaagg agtatgccca
     8521 ttatcactcg ggcgactcaa catcgcaaaa cgaccgttta tcttacgagg gaacaagact
     8581 ccattccgat tgaaaggaat aaaggcattc tccaactggt gaaaagtaac aaaatcatag
     8641 gtgtaggcca caccgatagt aggaccatga tagccattac accaggtcac atagtagcgg
     8701 tcttcgataa agcaaacccg tgggtcatat ccatagaccc aggttccaac ctcagcatca
     8761 tcacattgaa actttaacgg ttcttcgttg atatcccaat gaacagcatc cttgctgaat
     8821 cccacatgca aacgcatgcg acgattagta tcatcacaac ggaacacccc tgcatagcca
     8881 tccttaaacg gaactacggc actgttgaat atactgtttg aagtagggag caagtcgcgc
     8941 ggaataatcg gattggccga acaacgccac actacatctt tacatcctgc cggacgttct
     9001 tcccaaggca tagccggcaa agcagcacct gcaattttaa tttcttccat gattcgatta
     9061 aattaatatt atgtatatat cttgtttata ttgaaaatct ctttttattt cttctttccg
     9121 tccggatatg tgaaaggtac cagccaagtc acgataaaag ccggtatggt agcgataagt
     9181 acccagataa agaaatcgcg ataacccagc caatcgctca ggtatccgct catcattccg
     9241 ggaagcatca cccccagatt cataataccg gtagcaaaag cataatgtgc catctgatgt
     9301 ttgccgggag ccacttgctg catcataaag agcatcaatc cgacaaaacc aaacccgtaa
     9361 cccaagtatt cagacacaat ggccatagca ataatccata gatcggaagg ctggtaaagg
     9421 gctaacagga aatataccaa gaacggaata ttaaaagcgc aacataaaga aaacaaagtc
     9481 ttccgaagtc cgaaagccga aatgtaataa ccggccaaaa gcgaaccgag aataaaagct
     9541 cccgctccga acgtaccata taccagtccg atatcctgag tgctgagtcc caatccacca
     9601 tccgcaaccg acgctttcag gaacaacggt acaatcttga tggcatatcc ttcggcaaac
     9661 cggtacaaaa tgataaagac aatgtagaaa gcaatatgtt ttttttggaa aaaagagcgg
     9721 atgacttccc aaagcatatt caatgcgtca ctcatcgtat tcacttcacc ggaagctcct
     9781 cctcccgaag gcaaaatccg gatgtggtaa agaccgatca gaatcataat acccgcacac
     9841 atcaacatga caatcatcca ggcatgtacc actccaaatt catccttcag catacctgcc
     9901 agccaaacca agcctccgtt ggcaagtatc ttggccagat tataaaaagc tccctgccaa
     9961 ccgatatact tggcttgctg ggtagcagtc agttcagtca ggtatactcc gtcacccgca
    10021 atgtcatgag tcgcaccact gagagcaatg atccccatca gagcgatggc ataacgaaaa
    10081 aagtcgggca gcggcagcga aagtgctacc aatgcaaatg ccagtccggt aatgatttcc
    10141 gtagcgacaa caaagtattt tttcgtttta aacatttcca gaaacggact ccataaaggc
    10201 ttcaatgtcc agggaagcat aatgagagaa gtccagaaag caatctgtgc attcgacact
    10261 tccatatcgg aaaacataag gacagaaacc atcgaaaggg ccacaaacgg caatcccata
    10321 gcaaagtaaa cagtaggcac ccaacataca gggcttatcg gctttttatt catcagttag
    10381 ttttttataa taattccatc ggttaacaat tccagtaagc aaagataggg gatattaaaa
    10441 acataaccca agattacgac aagaagttgc tttcattatt taataataca actcacccgg
    10501 gaaaactact aacctctatc accctttttt tattaaactt tatcaatacg acacacgcaa
    10561 agaagcaccg aagactttca tccccgatgc ctctcgcccc cttatctaca atctaaacac
    10621 ctctattgct tcacatataa atttatctca gcaaacccgg tataattatc cggagtcaga
    10681 cagtttattc tgaattcctt tacattcggg ataggtggtt cgatggccgc atattgcgga
    10741 tcagcccctt taaaatttct gaaagtcaag actctcgggt aagtaaccca ctcggtttca
    10801 ccctctttcc gaaccttaat ctcagcactt ctcaggttat aacccgatcc gtaggcactc
    10861 tgtttagtga ccgaaaatcc ggttaaggta acaggccggt ccagtagcgt attccaccaa
    10921 cactctccgg cattagccac tccccatgta aaccaagtag tatttatctc accgtcaata
    10981 gccagatgtg caccatattt ggcatcatca tcggcataaa cattgctgca acttacactc
    11041 cacgcacttc gatctacagc ggaccaattc ccgggtttcg tataactggt ataaagcacg
    11101 ctggtataaa tccggatata aaccgtcttc atagatgtac tgacagcctg ttcgtccatg
    11161 cccgtaactc ctttaagcgt cacgggaagc acatatccgt caggattagt caacttttct
    11221 atattcttca aaacgacctg aaaagatgaa tcggccactg tctgtcccgt ttttaagaca
    11281 acttcacttg tttcaatggt ataattatct tggggcaaca acttacattt cgttttattg
    11341 gcagaattgt aagtatccac tttcagcgta tctactccca aagcggcagt gacatcccgc
    11401 gtaaccagct gtacggcaca caattgtatt tcaaaatcag aacggtcggc agtagaggaa
    11461 ttgctcacac aatccaccac taccgcagca cccatttcgg cccccggtgc aactcccgtt
    11521 ctgatatata tcttttgata tttgtccatt tcatcatcat cgttgctgca cgaagccaac
    11581 gatacaaaac ctgttatcag gcagattaag gtcacaaaat tcaaatgtct attcatatct
    11641 tatcttcttt ttacatagtt attgcttatc aaaacgaaca tgctctttcc agacaagagt
    11701 tcctcctgcc accaaatcgt atccgtgtcc ggtacagtcg acaaaggcat ttcccttacc
    11761 ttcatccatt ttccaatagc ctatcaggtt cggatcggcg ggcttcacgg caaaatacat
    11821 gttggactga atttgcgtct ggctgattgc gctcttccaa agacgcacct gggccatctg
    11881 acaattgttg cggaagtagc taccgctcga aaccatgttc atcttgtcga atcttaccgg
    11941 gccacccttt gtctgcagag tcacgtcgag cactccgttg atataaatcg acaataaccc
    12001 ggaagaatta taaacgaagg ccagatgata ccacttattc ttctcaaaca aagtcaccgt
    12061 attgacctga cttccaagtg tcttcacctg taatgaatta taagggatca tagcgtcacc
    12121 gaaacggata taaacctcgt ggtcgctgct gcccgaatta aatatagcct gattattaat
    12181 atcgaatccg tccatctgta cccaagcctc gagtgaccat tcattggttg tcactcccca
    12241 caattcgtcc ttggcgggct tcacggcatt ggtcgtattc ataaacggta cagactgtat
    12301 cagcggctta tccagcaaaa tgataaactt cgacgaaagc ccgattgtgg acaccggtcc
    12361 ctgaatttct gtgagagata ccggaatagc atacaattct ccgttttcgt ttgaataagg
    12421 tttcactcta aactcactgg ggattgcgct aacatcgcct gccgctatct ttatctcttt
    12481 gtcataagta aaatactgct cgggaaggac ttcgtacgaa gtttcattag cttcattgta
    12541 ctctttaaga atagaaggat ctaccgtcag gacagcagtc acattttcgg ttacaggctg
    12601 tcccacacgt acggtcagag tagttgttgt tacattttca ggatcaacgg taacctttgc
    12661 cgaaccattc tcggatgctt cattcaaata aatcgcattg tcgataacct ggtaatcggc
    12721 atcgttgcat cctgccagga tcatcggcag aacgaaacag gcaagcaaat attgttttat
    12781 tgttattctt ttcataatca aattctttaa agtcatttta cagcaggatt cattattctg
    12841 attgcttcac gcaggtactt atattcgatg tcgcccggat agtcatattc catgtgatag
    12901 gtgcctactc cacccttccg tacctgtttt ccgtcaatag tcggagtcca gcgtgccatg
    12961 ccggcaagtg ctctcatttt gtttccgtaa cgatctacat aatcacctcc tcctgtcgga
    13021 gcataagatt cgaaattctc cgtaacgatg tacatattag ccactttctc cggaggaagt
    13081 attcctttaa agttggcaat cgtaccagcc agacgtctgt caagattagc gtcggaatta
    13141 cccgcaaggt tagagtatgc ctgcacaatg aaatagtcaa agtaaggccc ggtttccgga
    13201 tgaatacttt gaggctcgcc atcaatcaca agtaaccgtc ccgtacccga tttaggtccg
    13261 attcttt
//
