LOCUS       c00018_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GOGHGBIN_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:41:25
            Original ID  :: gnl|Prokka|GOGHGBIN_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 68864
            Orig. end    :: 93503
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[78864:83503]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="2"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             530..1534
                     /locus_tag="ctg18_44"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
     CDS             complement(1629..3224)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_45"
                     /sec_met_domain="MFS_1 (E-value: 2.7e-13, bitscore: 44.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIVLFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFSEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(3229..4296)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_46"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 7.7e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             complement(4309..4749)
                     /locus_tag="ctg18_47"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGTEMEASRITECIEDLKRLHEVLNEI"
     CDS             complement(4907..6757)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_48"
                     /sec_met_domain="Alpha-amylase (E-value: 1.9e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTDDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             complement(7217..8509)
                     /locus_tag="ctg18_49"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVMLRAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             complement(8523..9758)
                     /locus_tag="ctg18_50"
                     /transl_table=11
                     /translation="MANYDYETAVELINKEPPTIPLLMQKAKALKGIGSNAEALRSIRQ
                     MIAEDSTNQQAHIEAAECCKAMAKYNDALDYYRKAISLNPKNKYARLQFINLLCNTKNY
                     AEAFGESSMMSETDSSAVVLHLQAQSLEGMQQILPAIGCYEVIQDKYPDDYLAAAKLGN
                     LNIVAGYPEYAIQATERYRERDSTNLIVNQQNALAYCHAEQYPTAIKRYEKLCQQGDSS
                     TQTLYYLGVSYYADEYYYEAHACFSKLQKEMEENPNLLYYLGRCCAKTSWKKEGIEHLE
                     KAIELTIPKDSTMIRLYKGLVDCCKLAQDTPKQIQALRELYKYDKTNHKLLYDIAWNYS
                     YQLKDNKSAERYLQAFLKTRKANARKEEPVSEKGELVLGLENYYNAAENWLKDLQKEKF
                     FKEGIPLESQKQ"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_51"
                     /sec_met_domain="OAD_beta (E-value: 1.4e-152, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11164..11595)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_52"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.8e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             complement(11621..12535)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_53"
                     /sec_met_domain="OAD_gamma (E-value: 4.4e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             complement(12556..14109)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_54"
                     /sec_met_domain="CT_Btheta (E-value: 7.2e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(14235..14639)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_55"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.5e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14873..15856)
                     /locus_tag="ctg18_56"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALRDAHQNGFRHMEF
                     MDVGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             15974..16516
                     /locus_tag="ctg18_57"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             16722..17219
                     /locus_tag="ctg18_58"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             17222..17554
                     /locus_tag="ctg18_59"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             17551..18342
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_60"
                     /sec_met_domain="F420_oxidored (E-value: 5.6e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVPHYGVFYPMQTFSKQREVDFKEIPFFIEASSTEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             18363..18884
                     /locus_tag="ctg18_61"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALVFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             18868..19497
                     /locus_tag="ctg18_62"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(19690..20082)
                     /locus_tag="ctg18_63"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(20187..21227)
                     /locus_tag="ctg18_64"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             complement(21246..22628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_65"
                     /sec_met_domain="MBOAT (E-value: 3.1e-21, bitscore: 70.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             complement(22632..22874)
                     /locus_tag="ctg18_66"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             complement(22889..24403)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.7; E-value:
                     2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_67"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-81, bitscore:
                     268.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
ORIGIN
        1 tgatccgatg gacttgagcc ttgccgtact gggggcaaag aaacacgtcg aagatatgac
       61 tgaagatgac ctttacaacc cctggtgggt gacgctggaa gataagggag tgggcacttt
      121 gctctatcgc ggcaaatgga atctgttcga tcagatcatc ctttcgccca cgctgcttca
      181 agccacaaaa ggattgaaat atgatcacaa tgaagttttc atgcgcgatt acctgtttca
      241 gcaggatggt aaatataagg gtgctcccct gcgtacatat ggtggcagag tgtggttgga
      301 tggttacagc gatcatttgc ctaccattat atatatgagg aaacaataaa aaacctttat
      361 ttgctacgta gacattacaa acagctctta aaggatggga aataatttga aatagaattg
      421 aattacgctc ctcaaacgga tatttccgcc cgagggtttc tctattcaaa ggattattct
      481 tacttttgca tagaattttt aattcactaa caataaactt ttaaacaaaa tggttaatta
      541 caaagattta ggtctggtaa acactagaga tatgtttgct aaggctatca agggtggata
      601 tgcaatccct gcattcaact tcaacaatat ggaacagatg caggctatca tcaaggctgc
      661 tgtagaaact aagtctccgg ttattttgca ggtatcaaaa ggtgctcgtc agtatgctaa
      721 cgctacattg ttgcgttaca tggctcaggg tgctgtagaa tatgcaaaag aactcggctg
      781 caaaaatcct gaaatcgttt tgcacctcga ccacggagat actttcgaaa cttgcaaaag
      841 ctgtatcgac tcaggcttct cttctgtaat gatcgacggt tctcaccttc cttacgacga
      901 aaacgttgct ctgactaaga aagttgttga atacgctcac cagttcgatg taactgtaga
      961 aggtgaactt ggcgtattgg caggtgtaga agacgaagtt tcttctgacc accacacata
     1021 tactgaaccg gacgaagtag ttgatttcgt taccaagaca ggttgcgatt cattggctat
     1081 ctctatcggt acttctcacg gtgcttacaa atttactccg gaacagtgcc acatcgatcc
     1141 gaagacaggc cgtatggttc ctcctccgtt ggcattcgac gtattggacg gtgtaatgaa
     1201 agaacttccg ggattcccta tcgttcttca cggatcatct tcagttcctg aagaagaggt
     1261 tgcaactatc aaccagtttg gtggtgcact gaaagctgct atcggtattc ctgaagagga
     1321 actgcgtaaa gccgctaagt ctgctgtttg caaaatcaac atcgactcag actctcgcct
     1381 ggctatgact gctgctatcc gtaaggtatt cgcagaaaaa ccggctgagt tcgacccgcg
     1441 taaatatctg ggaccggctc gcgacaatat ggaaaaactc tacaagcaca aaattatcaa
     1501 cgtgctgggt tctgacaaca agttagctga ataaattcca aatctagtat ttaaaagttt
     1561 tacttgattt aatttatatt ttaagaagcc actcaagcaa ttgggtggct tttttgtatc
     1621 ccttctcatt ataccatatc gtcacccgtc ttcacaacag ccaccttcag cgttttatgg
     1681 aaaggaatga acgctgcgat gacagcaatc accagtgcca gtatcagtac atagccgatt
     1741 agggttttca gggcaagcag cagggattgc tgctgcaaag tggagtacag gctgttggct
     1801 gccaattgtc cggcctcgct gaattcgtgc ccttgcgcca gggcattgct caatgcctga
     1861 ttgtattttt gttcggccag cggattggtc agcgtcatgt tttccgaaag aatgttcatc
     1921 ccctttgcct gcagatagta aagcatgttg ttaaagaacg aagcggacag gaccggagct
     1981 aatactgagc ggaatgaaat caggaagaag gcattggaca acgtcaggcg cgggtctaaa
     2041 tcttcgacaa caaacacacc gaacgcaatg aatatgacca tcatccccac tccccggaac
     2101 aggatgggga ggtagagcat ttcataagtt ccataagggg tgataccaaa gtagaggata
     2161 gccagataga tgacgtagca gaacatacct cctgaaatga ggaagcgaaa ccgccatcgt
     2221 tgccatcgga accaccagaa gcaaatgacg gctcctacca catatccggg caatagccac
     2281 aggctcagcg aattggcgtg tatgctgtct acccggatga tgctgttcat atagttggtt
     2341 accagtgaac tggtggctgt caggaacatg gcgagtacca tgaagccata tccgatgatg
     2401 gatttatgca gaaagagtgg tttcaggctg acaaagggtt tgccttgtgt acgctgccga
     2461 tggatgaaga gaactatcag gagcgggatg acgaatacat atactctgat cttcggggat
     2521 gcgaaccaat cgagtgtttt cccgtaggta aatgtataga gcgttagcag gaaagcggtg
     2581 gcgatgatga acatgcttct tccgtccatc tctttgaacg gaatgtgcat gggacgcctt
     2641 gcatagcgga agaaacagat gacgaacaga atggcgatca gcaagaggat ggtgacaaaa
     2701 tagtacatgt gctgccattg gtagtgatag gccagttgag cggtgatagc catcgatagc
     2761 tgacctccgg agaaaacgat ggggtagaag taggcataga attcacttcg tacgtttttc
     2821 ggactgaaga gcgggcggat caggatgatg aactccaaca tgacgaaggc tttgagaaat
     2881 cccatacaga aactgcatac catgatgaca tccatactac cggttttggc gcataccagg
     2941 ctgaagaata tctgtagcag caggtcagtg agcagtaagg ttttcggagt ggctatggtg
     3001 cgtattttcg gtacgatggg ataggcaaca gccatcccta ccgaagctga atagtaagcc
     3061 atggtaatat cttcgctcaa tactcccagc gtgttcgata cttcgaccat acttcctgtg
     3121 taggcaccgt tgagcagggt gatgggaaag atgacaataa acatggtcac gatgcccaac
     3181 cattgaggca cccagggacg ggtaggcaga ttgagcttca ccataagcct aagggcggac
     3241 cgcttccgtt tctaccatca tccctgcacg gagacattcc atctcttcgg gtgaggcgtc
     3301 attgagatcg atgcggaccg gaatgcgttg ctgcactttg acgaagttcc ctgccgaatt
     3361 gtcggtcggt accagggagt atttcgatcc ggtggcttcg gaaatggcgg ttacggtccc
     3421 gtgaaaagtg cgtccgctga aagcatctac tttgatgcgg actttttgcc cgatatagat
     3481 atgggctatt tgagtctctt tataattggc tgtcacccac ttgtcattgc cccgtaccag
     3541 gtaggaaaga gtttgtccgc cttgtacgaa ctgtcccggt tcaagtgtac gtcgtcccgt
     3601 gtatccgtca tagggtgcgg tgacaacggt atacgacagg tttagtcggg ccatctccag
     3661 gtcggcttcc ttccggagga tattggcttc ggcgcctgta ctgcgtttgc tggtttcgga
     3721 atactgcgat tgggccgctt ctttttgtcg caacagggcg ttgtatcttg cccgggtcgc
     3781 ttcgaagttc gctttggcca gttcataatc ctgttggctg acggcctgct ttttcaggag
     3841 ccgggtatat cggttcagtt ccgcttcttg ctgtgaaagg cgtgccagtg tttcggctat
     3901 gttggcttct tgtacggcta catttactcc tgaagtccgg atgccggagt ttaacacttc
     3961 ctttgatccc aaggcatcca tcaaggccgc ttccgcgtct ttcagccgga tccggtattc
     4021 ccggtcgtcc agtatcagta acgtgtcgcc ggcatgaaca tactggtgtt cggtaaaacg
     4081 tacttctttg atatagcccg gtatccggat gtttagcgga gcgatgtatt gatccactac
     4141 ggcatcattg gttatctcgt agcgggcgta tttccagaag tagtttactg tccatgaaat
     4201 acctgccaat gccagcagga tgcatactgt gttgagaaag atgttcctga acttcagtct
     4261 tctcaattgt tttagcttta tctgatgggt ggacatggcg gatttctttt agatctcatt
     4321 gagcacttca tgcagtctct tcagatcttc gatgcattcc gttatccggc ttgcctccat
     4381 ctctgttccg gtttgggcat agatatcgtt gatcaggggt ttcacggtga gggcaagttc
     4441 ttcgccttgg ggcgtcagga aaatcaggcg gtttcggcgg tcggaggggc cttctttccg
     4501 tatcacccag tttttctttt ccagattatt aatcagattg gtcaggcaag ccttgtcctt
     4561 tgctgttttc tcagccaggg attgctggct gatgccttgt ttgttccaca ggcagttcat
     4621 tacttgcagc atctcgaagg tcatatccac gttgtgacgt ttgagtaccc gctgaacggc
     4681 ctggcggaat gccatccagg ttcgtaaggt ttgtaggaca agctcgcgct ccgattcgtt
     4741 gtttgtcatc gtcgtattct tttagtcgct gcaaaggtag gaatattctt cgataatagt
     4801 caaacgtttg actattatta ttcgcattag gctacacaaa gggcacagag gatgtcgggt
     4861 gaaatccttt gtgccctttg cttatgcggt tataaccggt gtgagattaa agctctataa
     4921 ccatcgattg gcggggtgcc attgtcagtt cttcattgag tgccgttact tttccgctaa
     4981 tgacgtcttt tccttgagtc ttgtctttca gcacttcggc atagtatttc aggggaagtt
     5041 tcacctcttt atccgtaccg ttcaacagga cgaataccgt tttcccttta tattggcgtg
     5101 cataagcata tacgccgtgc tgcaccatga actgtttcat gctgcctttg gcgatcacat
     5161 cgttgccctt acgccagttc agcaggttgc ggtagaagtt atagctttca ttctgcaatc
     5221 gggtacgtcc ctcgggagtc agggcattct ctttatcgtc cgtccatccg cccgggaagt
     5281 cctttcgtac atagccgtcg cttttactct ttactccgtt catcatcacc tccgttccat
     5341 aatagagttg cgggatgcgt cgggtggtca ataaaagggt ggaggcctgt ttcagcatat
     5401 cgaggttttc gccttcaccc aagaaacggt cggtgtcatg attctcgatg aaagccagta
     5461 cggaagccgg attgggatac agataatcgt atacaaaatt gttgtagaca cggtccaatc
     5521 ctttgaacca agtgtccgtt tgttcattct tggccgtgtt gactttgtcg aagaagctga
     5581 aatccatgac tgttttcaag tgactgttgc gcggggcgga gagcttggag tctttctgcc
     5641 accaggctgt ataggccggt tcggtaaccc aggtttcgcc caccgtgttg tagttggggt
     5701 attcttcgtt cagttctttc atccagttgc tcatggcatc gtaatcggca tacgggtagg
     5761 tgtccatccg gatgccgtcg atatcggcgt actcaatcca ccacaggctg ttctgcaaga
     5821 ggtatttgta tacgtgaggg ttcttttggt tgaggtcagg catggcttcc acgaaccagc
     5881 cgttgttcat ctggtcgaaa tcgtactccg aggcatacgg atctacatgt ggagtcagct
     5941 tgtaggaagt ttgcacaaag ttgttcttga agtccgcatg gttgaaccag tcctttgaag
     6001 gcatgtcctt gatccaggga tgttctactc cgcaatgatt gaagatcatg tccatcacga
     6061 ccttaatgcc ccggttgtgg gctttcgcta tcagtgagcg atattcctcg ttagtgccga
     6121 aacgtgggtc taccttgtaa taatcggttg ttgcatatcc gtgatatgag ccgcctttca
     6181 tattattttc gagtaccggg gtgaaccaga gtgcggtcac tcccaagtcg gtaaaatagt
     6241 ccagattttg ttcgataccg gccaggtcgc ctccgtgacg tgcgttcggg tcgttgcggt
     6301 ccactttata ttcggccatg ccttctatcc ggtcgttatc cggattgcca ttggcaaaac
     6361 ggtccggcat cagcaggtat aatgcatccg atgcgtcaaa acctttgtga tcgactccgg
     6421 ctttgctgcg tgctttcaat tcgtactctt tcaccaattt cttctttccg accgtaaatg
     6481 tgatgggcat cttgcccggc tttacttctt tatcgagatg taggtagaca agcaggtaat
     6541 tgttgctttc cagtttcacg acgctgctga gcgatacacc gggataattt actgatacgg
     6601 atgcctggcc gatgccttca ccgtatacca ttaactggag ttccggattg ttcataccgg
     6661 tgaaccagaa gggcggatcg attttggata tgttcatggc tgcataagtg gttaatgaca
     6721 gtaggaatga acctaagagt aacaataatt ttttcatgat attagctcgt tattatttaa
     6781 tgttgctaat atagggtaaa tcatcggatt gttttccgtt ttctttctta ctgtgtgcca
     6841 tctatttatg caaacgtttt cattggagaa ttctccggga tggagctcaa ccgataagga
     6901 gcacttttcg atgcaatcag gtgaacgtga cgtccggaaa aggagatgcc gtcatagctt
     6961 cggctacgca gcaccgtaac ttcggctacg cagcaccgta actttgatta cgcagcaccg
     7021 taacttcggc tacgcagcac agtaacttta gctacacagc accgtaattt cggctgcgtg
     7081 ccgatgtgac ttcggttacg tgctactgtg ccttctaccg cacatcttca aatttatttt
     7141 ccattattct ccctctgtga aactctgtct gcactcagtg gtgaattgtc cgaaacgatg
     7201 catctatccg atcaattcac ttttctccct ttaagaattt ctcttttcgg atgctttcca
     7261 atttattggt ggcacttttg tagtaatcta tgtagggtgc gggttcttct tcgtcatcat
     7321 ccggctgctg tagtactgca ttttgtttgg attttgttcg cagaaaagcc tgcaagtaat
     7381 gctctgtggc tttagtatct cctattttgt ccgataagaa cgccaagtta taaagtaaaa
     7441 tatgcttgtc aggggcatat ttgtattgtt ctttggtagc cttgatttgg tcccgggttt
     7501 gcttggtttg cctgtagcag tctgccaagc ctgagtataa gcgctccatg atactgtcgg
     7561 cggggatagt cagggcgata gcctggttca gatatcctat tccctcttgt ttccataatg
     7621 tcttggagca cgaacgtccc aaatagtaga gtaggttggc gccgggtgac tggcatgatt
     7681 ttgctttgag cagccaatcg cgcgctttat agtattcttt cgtagcgtag tagctgactc
     7741 ccaggtaata acatgtcagc agtgtgctgt ctccccgggc ggtcagatcc tgataacgtt
     7801 tgatggcggt gggatattct ttgcgcagac aatacgccag tgcgttttga cggttcactt
     7861 ctacattggt gctgtccgtc cggcggtatg cttctgtcag ggcaattgcc ccttcgtaat
     7921 ctttcattgt attgaagata ctgcccagct tagctaccga gagatagtcg gagggatatt
     7981 tcctgatgat ggaaagatag caaaacatac tttctaccgg catgccggct ccttccatgc
     8041 tttccgccat cagtcgcaat acggtggcgg aactgtcttt cctggccaat gcgatactct
     8101 cacgcaatgc atcgccgtat cgctgatagt tgtataacaa gcgggtgtat tgcaagtgtg
     8161 cgtaaatatg ttcgggattg agttccatca ccttccgata ataccccaag gcctcgttaa
     8221 atttgctcaa ttgcctgcaa cattctgcag cctctaccaa tgcctgctga ttttcgggca
     8281 gctcgataat gatatgttgc aaagtggaca gggcttcggc ggtacgccct aaacctttta
     8341 aagctttggc tttctgtatg agtaactgtg gtgatgcact ttcttcatca atcagtctga
     8401 tcaccgtttt atagtcatag tttgccattg cttcttgaac ggaggcggtg ttctgagctc
     8461 gcagcattac gctgaagccc agatagagga ggagtatcca atgtttcatg gggggacaga
     8521 ttctattgtt tctgactttc taacggtatt ccttctttga agaacttttc tttctgtaag
     8581 tctttcagcc aattttcggc agcgttgtaa taattttcaa gtccgagtac aagttcccct
     8641 ttctcactca ccggttcttc tttcctggca ttcgcctttc gggtttttaa gaaagcctgc
     8701 agataacgtt cggccgattt gttgtctttg agttgatatg aatagttcca ggcgatgtca
     8761 taaagaagtt tatggttcgt cttgtcatat ttgtacagtt ctctgagagc ctggatttgc
     8821 tttggagtat cctgagccag tttacaacaa tccaccaagc ctttgtaaag tcggatcatg
     8881 gtgctgtctt tgggaatggt cagttcgata gctttctcca ggtgttcgat gccttctttt
     8941 ttccaggaag tcttggcgca gcaacgtccc agataataga gcagattggg attttcttcc
     9001 atctcttttt gcagtttgct gaaacacgcg tgcgcttcgt aataatattc atccgcgtaa
     9061 tagctgactc ccagatagta taaggtctgt gtactgctgt ccccctgttg gcacagcttt
     9121 tcatagcgct tgatggctgt cggatattgt tcggcgtggc agtaggcgag agcgttttgc
     9181 tggttgacaa tcaggttggt ggagtcccgt tccctatagc gttcggtagc ttggatggca
     9241 tattcgggat atccagccac aatgttcagg tttccgagtt tggccgcagc cagataatcg
     9301 tccggatatt tatcctgaat gacttcatag caaccgatag ccggtagtat ctgttgcatc
     9361 ccttcaaggc tttgagcctg taggtggagc actacggccg aactgtccgt ttcggacatc
     9421 attgaacttt ctccaaaagc ctcagcatag tttttggtgt tgcaaagcag gttgatgaat
     9481 tgcaaacggg catacttgtt tttgggattc aggctgatgg ctttccggta gtagtccagc
     9541 gcatcgttgt acttggccat tgctttacag cattccgctg cttcgatgtg tgcctgttgg
     9601 ttggtggagt cttccgctat catttggcgg atggaacgta gagcttccgc attgctgccg
     9661 attcctttca gggcttttgc tttctgcatt aacagtggga tggtgggagg ttccttgttt
     9721 atcagttcaa cggcagtctc gtagtcatag tttgccattg cttcctgaat tttgttttga
     9781 ttctggccat cagtagggga ctgaggcaaa gacagaaaat aaggaagagt ggtttcattg
     9841 ttcttgttct cataggacgt attgttttat tgtccgcaag ttagtaaaaa tatccattct
     9901 acgaaaggtt cgtaatatct tttagataga ttaacgcaaa aaaaagacgc ccttctttgc
     9961 gaaaagaagg acgtctacct tactaatgaa aaaatatcgt ttacatgagg aatccgagca
    10021 ggataccggc agctacagcc gaaccgataa cccccgctac gttaggaccc atggcgtgca
    10081 tcagcagata gttggtcgga tcatattcca aaccgattac ctgtgaaata cgtgccgagt
    10141 cgggtacggc ggatacacct gcattaccaa tcagcggatt gatcttattg cctttcttca
    10201 agaatagatt gaagaatttg acaaacatga cacctgacgc tgttgcgatg atgaaagaga
    10261 atgcaccgag gataaagatc aagatagaat cccaggtgag gaattgtgaa gcttgggtag
    10321 aagctcccac agtcagtccc aacaggatag tgatcacatc gatcaacgga ccactggccg
    10381 tatttgccaa acgacgggtt actccacttt ctttcagaag attaccgaag aacagcatac
    10441 ccagcaaagg cagacccgaa ggaaccagga agcatgtaag caacagaccc acgatgggga
    10501 agattacttt ttccgtatgc gatacgattc tcggtggttt catgcggatc agacgctcgt
    10561 gtttggtggt tagcgcacgc atgataggtg gctgtatcac cggcaccagt gccatgtaag
    10621 aataggctga cacagcgatg gcacccatca ggttgggagc cagtttggac gaaaggaaga
    10681 tggccgtcgg tccgtcggca ccgccaatga taccgatagc acccgcctgg ttgggttcga
    10741 acccaatgag cagggcaatg atatacgcgc cgaagatacc gaattgcgcg gcagctccga
    10801 tcagcatcaa tttggggttg gagatcagcg ccgagaagtc cgtcatggct ccgataccca
    10861 ggaaaatgag cggcggatac cagccggagg ttactccttg ataaaggatg ttcagtaccg
    10921 aaccttcttc gtaaataccc acttttaatc cggcttccat attgaatgga atattaccga
    10981 tcagaatacc gaagccaatg gggatcagca gcatcggttc aaattctttg gctacggcaa
    11041 ggtagataaa gaagagaccg attagcaaca tgaaaagatg tccgggtgtc gcgttcgcaa
    11101 aaccggtgta tccccagaag tcaacaaggt tattccctaa gaatgatacg aaatctccca
    11161 taattattca atgattacga ggtctgtacc ttcaagtaca gaatctcctt tattaacttt
    11221 aatttctgct acttttccgt ctttattggc attgatgttg ttttccatct tcatagcctc
    11281 aaggatgatg atcgtctggc ctctcttcac ggtatcccct tctttcactt ttatgtcgag
    11341 gataacgccc ggaagcggag atttcacacc gtcttttttg gaagctgtcg gttgtttggt
    11401 tactaccgga gcacctgttt ccgttttcgg agcggctgcc ggacgggtca ccggtttcgg
    11461 agcggctttg acgggcttgt ccaactctac tttataagag gttccgttca cttcaacgtt
    11521 ggctatgtta tcttctacat cgttcactgt aacgttgtaa aggttgccgt tgattttata
    11581 tttatattgt ttcattgctt cattttatta gggttagtaa ttatcttttc ggagtctgac
    11641 gcagtgtgta gatcttcgaa ctccaggggg agtaggtgcg tttcactttg ttgatagtca
    11701 aaatcatgtc ttcaacgtcg tgagcgtcat tcaggtattc atgcaaagcc atggcgattg
    11761 cggcggtttc ttcacctgtg tggctaccca ggttcttttc cttcgcttcc gtcttgtcgg
    11821 tgataccggt ggctttcatc gcgtttttct tacccagtct gacagctacg ttacctaccg
    11881 ccttgaatga aagatacaag agtaccaaac ctatgaatac gaccgacatg gcgatgatgg
    11941 ccataccgat accgatagag tcgtgtttct tgaagttctc gatcttcggg tttttgtcga
    12001 tagtcatatt gttggtgctc ggagtgacat agctgtgttc tccttcacct tttactaccc
    12061 agttggcact tccgtctttt tcgcgagcgt atgaacggtc ggcaagctga ccggcgggta
    12121 tggttacttc gtcaatcaga gttttaccgt tagagtcata caaagcaatg taattctctt
    12181 tgttcgggtc gagcgtaaag ttcacgtgga acgtaccccg gttaggcatt ccgtctgccc
    12241 agaacaaagc atgttggcgc ggcttgatca gagtcagcac gtcgcctttg ggaataggat
    12301 atttggtcgg attgttttta tcgttcgtca gaaagcaacc ttccagattt acagaagcga
    12361 aagaggtgtt gaatatctct atccacgcat tgtgcagtcc gtagtcatcc tgatagttct
    12421 ggtcgttgac gaccaaaacc tcattgattc tcagactggt ggcactttgc gccctgagcc
    12481 ccatgcaaac cattgccagc agagcgataa atatcccgat tcttttctta ttcataacaa
    12541 tcgatgttta atttgttaca atggaatatt accgtgcttt ttagcagggt tggttaattt
    12601 tttggtctgc agctgttgca gggcgcggat cacgcggaaa cgagtgtttc tcggttcgat
    12661 aacatcgtca atgtaaccgt atttggctgc attgtacggg ttggcgaaca gtttagtgta
    12721 ctcggcttcc ttgtctgcca ggaattgagc agggttttcc tgatctttgg cttctttggc
    12781 atacaatacc gctactgcac cggcaccgcc cattacggcg atttcggctg tcggccatgc
    12841 atagttcatg tcgccgcgga gttgcttgca actcattacg atgtgcgaac caccgtaaga
    12901 tttacgcagg gtaacagtta ccttgggtac agtggcttca ccataagcgt acagcaactt
    12961 ggctccgtgc aggattacac cattatattc ctgacccgta cccggaagga atcccggaac
    13021 gtctaccaat gtcaccagcg gaatgttgaa tgcgtcgcag aagcgaacga agcgtgcacc
    13081 tttgcgtgaa gcattgctgt cgagtactcc ggcgaggtat ttaggctgat tggcaaccac
    13141 acctaccgac tgtccgttca tacgggcaaa accgataata agatttttcg cataatcttt
    13201 ctgtacttcc aggaattctc cgttatcgat gatggcgccg atcacttcgt acatatcgta
    13261 cggtttgttc gggctgtcgg ggatgatctc gttcagcagg tcgtccatac ggtcgatggg
    13321 gtcggtacag ttcaccaatg gagcttcttc caggttgttt tgcggaataa agctgagaag
    13381 cttgcgaata atcgccagac cttcttcacc ggtttcggca gtgaagtgag ttacaccgga
    13441 cttgctggca tgtacgcttg caccacccag atcttcctga gacacgtctt cacccgttac
    13501 tgttttcaca acagccggtc cggtgaggaa catgtaagat gtaccttccg tcatcagcgt
    13561 gaagtccgtc agggcgggag agtaaaccgc accgccggca cacggaccga aaatacctga
    13621 aatctgtggg atgacacccg aagccatgat gttgcgctgg aagatttcag cataaccgga
    13681 cagggcgttg atgccttcct gaatacgtgc gccacccgag tcgttgatac cgataacagg
    13741 ggcacccatc ttcatggcca tatccattac tttacagatc ttttgtgcca tggtttccga
    13801 cagtgaacca ccgaatactg tgaaatcttg tgcgaaaaca tatactaatc taccttctat
    13861 cgttccataa ccggttacca caccgtcgcc gaggaaatgt tttttctctt gtccgaaatt
    13921 ggtacatctg tgttgaacaa acatatccag ttcttcgaaa ctaccttcgt caagcaactg
    13981 tgcaatacgc tcgcgggctg tatatttgcc tttggcgtgt tgtttttcaa tagccttttc
    14041 gccaccacct aaacgagcct gagcacgaag ttcaataagc tcttttactt tttcaagctg
    14101 gttactcatg agtttttctt aatttaaagg gttataatat ttacaaccgg acgattgaca
    14161 acccggatgg ggaatttaat gcaaagaaaa attccgtttg tccgtggcgc ggatcgtccg
    14221 aatcgtacat ctttttagtg ttcgcagagt tctgtcagta cgcccagagt tgatttcggg
    14281 tgaaggaaag caatgttcag gccttcggca cctttgcgcg gagctttgtc gatcaggcgg
    14341 atctctttgc tttcggcttc ggccagggca ttggctacgc cgtcttcaat ggcgaatgct
    14401 acgtgatgaa cacctgcacc tttgttttcg atgaatttcg cgatggtact ttccggacat
    14461 gtgggttcca gtaattcgat tttggtatca cctactttca ggaaggctgt tcttactttt
    14521 tgatcttcta cagtttcgat gttgtagcat ttcaaaccta aaacgttttc ataatacgga
    14581 agggcttctt cgatactttt tacggcaatg cccaaatgtt caatgtgtga aatcttcata
    14641 actatatttt taaattttgg tattaatcgt cttttcggaa tggtataaaa cagcacaaag
    14701 aaaatcaatt cttgtttaat aaagaaattt ttctgcaatt aattatggtg aaaataggtt
    14761 taaaacctaa ggtgcatggg tttaaaaggc aggcatcgtt ggtttaaaac ctaagggatg
    14821 ttggtttaaa aggcggagag ggttggcgct gatccctgag acaggcggat gttcagacgt
    14881 atattttgat cagcaggtcg ttcagccatt gccagcggaa acggaaccat cgccgggtgc
    14941 tgctttgctt gccaccgaag cggagcacga agtcacgata gccgtgcttc ttaaatggga
    15001 gtccgacgtc catgaactcc atgtggcgga atccgttttg atgggcatcc cggagggctt
    15061 tccatacagc cagtataccc gggtattgca aggcataggt cttccgcata cctcccgaaa
    15121 accagagata ggcatcgttt cccgaataga tacaggcaga gcctccgata attttgtctt
    15181 tgtagcggac gatgaaaatc tttgcctgcc ggctgtgaat cagccgggtg tccatgtgtt
    15241 ggaaaaagat gatgttggga aaatgtttac ggatgcggga cgaatagaga tgcctcagca
    15301 tattcgaaaa ttcgcgtatc tcttctaccg tacgtgcctc gtctactttt gctccgtttt
    15361 tcaggccttt tttgatctgg cggatacggg aggggctgaa acgctgttcg gcgttttcga
    15421 tgccgtgaag cgagtttcgt acccgcagcc agttgacagg gaagtatctg ttggaccgga
    15481 aatatttgta gccgaacatg gcgttctcca gattgcggaa ttctatcaga aacgagttcc
    15541 gcaaagcctc cgtggtgagg tgctccagca tttcgccgaa tatcctttcc ttgtcggctt
    15601 ccgctatcag atattcgccc gtgccataga tttcgcagcg tttgatgaaa gcgggaggaa
    15661 acatgcggat gcttttgcgg atggcagcaa gcagtcgcgc aacaggtttt ccgtcttccg
    15721 aagccataat cagaagcggg gtgtagcccg gagtttcttc gtagatctga aatagctctt
    15781 ttgaatgaaa cgtattggtt ccgggaaaat ccggaatctc acttccttgg taatatgtag
    15841 tcagttttaa tggcatatcg ggacaaattt acatttttta tttctcttta caacatttgc
    15901 agggcttatt ttgttgagct gtcgttttgt gactatcttt gtggagatac tacaataaaa
    15961 tccgtttttg attatgttag aagaaattct tgaattcaac aaaaagttcg ttgagaacag
    16021 gggatacgaa aagtatatca ctaacaagta tcctgataag aaaatcgcca tcctttcctg
    16081 tatggatacc cgcctgacag aactgttgcc cgccgcttta ggaattcaca atggagacgt
    16141 aaagattata aagaatgccg gtgccgtcat ttcccatcct ttcggcagtg tcatccgtag
    16201 tctgctggtg gctatcatcg agttgggagt agaagaagtg atggtcattg cccattctga
    16261 ttgcggtgct tgccacatga acagcgacga aatgatagct cacatgaaaa agcgaggaat
    16321 caagtccgaa acaatcgaca tgatacgcta ctgcggggtc gattttaatt cgtggctggg
    16381 cggattcgac gatccggtga agtccgtcag gggcacggtt cgttccatag agaaccatcc
    16441 gcttattccg aaagatgtcc gggtgcatgg ttttatcatc gattcactga ccggcgagtt
    16501 gacgagagtg gaataaattg cctatctttg cgctcgaatc gccacggagc gcgccgattc
    16561 atgcaaagtc ctgcagggca taccttatat agacgggcat gccgggcggt acctcggttc
    16621 gcgtgtgttt gtgcattcta tggtgactgg cggtatattc aaataatgca aagtatagat
    16681 acatggaaaa tttcagtgaa ctaataaaaa atcgccgcag catgcggaaa tttaccggag
    16741 aagaactttc tcaggaagat gtagtcgctt tgctgaaagc ggccctgatg gctcctactt
    16801 caaagcgcag taacagttgg cagtttattg cagtcgatga taaaaagttg ctcagtgaac
    16861 tttcacattg caaagagcag gcttcggcct ttattgccga cgcggcattg gccattgtcg
    16921 ttactgccga tcccttggcg agcgatgtat ggattgagga cgcttccatt gcctctatta
    16981 tgattcagct tcaggccgaa gacttgggat tgggaagttg ctgggtgcag gtgcgtgagc
    17041 ggtatactgc caccgggatg ccttccgatg aatttgtgcg cggtgtgctc gacattcctt
    17101 tgcagttgca ggtgttgtcc gtcatagcga tcgggcataa agggatggaa cgtaaaccct
    17161 ttaatgaaga ccatttgcaa tgggaaaaaa tccatattaa taagttcgga ggtaagtaac
    17221 ggtgagtgcg gtaaaagcaa acaataaaga tacctacaaa gccacggcag tcacccttat
    17281 tgtgatgggg gtgctctatc tgatcgacaa actgatacac ttttccactt tggggatacc
    17341 ctgggtgatg aataaggata atcttttgct ttacactgcg gtgattttcc tctttattaa
    17401 gcgggataaa tccgtcggct tggtattgct cggattgtgg ttggtgctga acatcggcct
    17461 gattgtttcg ttgcttggtt cgatgtccgg ttatctgctg cctttggctt tattgataat
    17521 cggaggtata ttgtatttga tttcaacacg atgaaaagaa gtatagaaga tacgccgatc
    17581 gtatttatcg gtgccggaaa tcttgccact aatctggcaa aagccttata tcggaaaggt
    17641 tttcgtatcg tacaggtgta tagccgtacg gaagagtcgg cccgcgagct ggcacagaaa
    17701 gtggaagccg aatatacgac agacctcgca gaggtgaacc cgtatgcgaa gctgtatatt
    17761 gtttcactga aagattccgc ctttgccgaa cttcttcagg gcattgtcga aggtaagcgg
    17821 gaagaggcat tgatggtgca tacggcaggt agcatcccga tgaatgtctg ggaaggacat
    17881 gtcccgcatt acggtgtgtt ctatcccatg cagactttca gcaagcagag ggaggtagat
    17941 tttaaggaga ttcctttctt catagaggct tcttcgacag aagatgccgc gtttctgaaa
    18001 gccattgcct ctacactgtc caaccgtgtg tacgatgccg actcggagca gcgtaaaagt
    18061 ctccacttgg ctgccgtgtt tacatgtaat ttcaccaatc acatgtatgc ccttgctgcc
    18121 gagttgctta agaaatacaa tctgccgttt gacgtgatgt tgccgttgat tgatgaaacc
    18181 gcccgtaagg tgcacgaact ggaacctaag acggcccaga ccgggccggc catccgttat
    18241 gacgagaatg tgatcggcaa tcacttgcgg atgcttgccg atgatcctgc catgcagcgg
    18301 ttatacgagt tgcttagccg aagcattcac gaaagacaat aatcccgaaa cattaaataa
    18361 aaatgagcac aatcaattac gaccttaccc ggataaaagc acttgttttt gatgtagacg
    18421 gagtgctgag cgccaatgtc atccctttgc atccgtcggg tgaaccgatg cgtacggtaa
    18481 atgtaaaaga cggttatgcc atccaattgg ccgtaaaaaa agggcttcgt atcgctatta
    18541 ttacaggtgg gcggagcgat gtcgtgcgga aacgttttat cgggttgggg gtatccgatc
    18601 tgtacttcgg ctctgcggtg aagatacacg attatcgtgg tttccgtgac aaacacggac
    18661 ttacggacga ggagatactc tacatgggcg atgacgttcc cgatatggaa gtgatgcgtg
    18721 agtgcggatt gccctgctgt cccaaagatg cggttcccga ggtgaaagcg attgcccgtt
    18781 acatttcgta tgccgatgga ggatacggct gtggacgcga tgtggtggag caggtgctta
    18841 aagcacaagg ccaatggttg tccgatgatg ctttcggatg gtgatttcca gtatatacct
    18901 tatttattta tcagtatgct tgctaactta gatcgttata aaatcgtatt ggcctctaat
    18961 tctccgcgtc ggaaagagct gatgacgggc ttgggtgtcg attatgtagt aaaaactttg
    19021 ccggatgtgg acgaatctta tcccgatacg ttgcaaggtg aagagattcc tcttttcata
    19081 gcccgtgaga aggcagccgc ctatcagtcg atgatcggac cggaagagct tttgatcaca
    19141 gccgatacca ttgtctggca tgaaggcaaa gcgctcggca aacctgtcgg aaggcaggat
    19201 gccatagaga tgttgcggag cctctccggt aaatcgcacc aagtgattac cggtgtgtgt
    19261 ctcactaccc gagaatggca aaaatgtttc gctgccgtga cggatgtccg ttttgcgatt
    19321 cttgatgaag atgaaatcgc ttattatgtc gatcactatc agcccatgga caaagccggt
    19381 tcgtatggtg tgcaggagtg gatcggtttt gtcggagtag aatccatatc cggcagctac
    19441 ttcaatgtaa tgggacttcc cattcagaaa ttatacagag aattgaaaca actatagaga
    19501 gtgtgccgaa actcgtatat acaacggagt agcacagagt ctcacagagt agatttattc
    19561 tctaaagaac ttttataaaa aactctgtgt tgccttgtgg tgaattatgc cttccttgta
    19621 ggtcgcatga ttccgtatgg cgactccctc cgtgaaagga gaagagtgcc atgcgaaatt
    19681 atagtttgat catttgtttt ctgtattttc tttctccatt tcgatattga taattgtgtt
    19741 atcccatttg ttcatctttt gcgtacccaa atctaccaga aagcccggcc aaaatagaat
    19801 gttccacagg caggcattgt taaatgtaga ttccaggaca aagggagtcg tttggtaccc
    19861 ttcctttttg gctactagtt gtttgtcttc ccttttcttt ttgatttgta cagtgacact
    19921 attgtcttct ttgatttccg ctattttctg tttggtcgat gcttcgtaga ttttagttcc
    19981 attcattccc gtaaaggtga tatcttgttt ggaactgctg aataatgtac agcatgatga
    20041 aaatgaaata cagacggata gcaataataa aatctttttc ataatctaag tttttaatgt
    20101 gatataattg ttttctttgg tctaattatt tttttcggat cgaggatgct cttcttctgt
    20161 gtgtgctact gttatgggag gaacttttat tgcctgtggc aggtgtcttg atcctgataa
    20221 atggctttca gtaagcgtgc tcccagcagc ggacgataat gaccgggttc gtaataatga
    20281 tgtatgtcgg ctgtgtattc gttgattccc gtgaaatccc agacagcgga atcacccagt
    20341 atagccttca atatttttat gtcttcccgg ctggtctttt tctgatagta atccggaccg
    20401 atgatgaact tcaggttcgt gtggtgctta tcgcagattt ttttgatgga gcgaagtacc
    20461 tgaatctggc tggcaaatat aacaggaagt tcttccatac ccgcattcgt tcgcttcttg
    20521 aattcttttt catgacggct ccagtatatt tcgccatctt gcgcgatctc tttttctctg
    20581 ggattgataa aattgttcgt gtaaggctcc ctgacgggat ctcccggatt tataacccct
    20641 ttcatataag gagcatactt atgtcggatc agataatcta tgtaaggaat cattctgtcc
    20701 ggataaagga actcctgcag gaatctcaac tggaatccca attggctgat gccggctgct
    20761 tcggccgaaa acagatgatt gttgcccgat aaaggagcgt ttttgtccag tgatttttta
    20821 tccagaacga tcagtatatt tttcaggggt gcacctacag agtcgagcag ctgaagcttt
    20881 tgacggacgc cacccaggct ttctccgttg tcatagaagc gtacggcatg gtcgttctta
    20941 tccaggtatt tttcccattc tcctgtcagg aatgccatgg tacaggagtt gccgagtata
    21001 aaggagttat aggctatcga atcgcgattc tgcagataat tctgccatcc cacatgggct
    21061 tcgttgagta gcatgggaga gtcgtcgaat cgtttgtagg ggtgtaatac cctataagga
    21121 tcaaacataa aatagacaac cactatcggg atcagcggca ggatcagtaa aagcaacttc
    21181 aggcaaaaac gtgtcttggg ggagattctc gatgaatgat gtagcatgcg cgtaaagggt
    21241 ttcggttaaa attgtaaata gatgaaagtt tccgtgtcaa atttgcctaa catcagcaga
    21301 gcgaatacca acagatagta gacactccac cgtaaccatg cgggttggcg ttcaagtgtt
    21361 tccatcaggt tgtacttaga tgcataatat tcgtagatca acaccagtaa tagggccgaa
    21421 cctgctacga tgcaattatg atcgcgtatg ccgatgttca tttctttcca ggaagaatgt
    21481 acctcgaacg agatgttccg taagaaatac caggcatcgc tcagcgattg tacacgaaag
    21541 aatataagcg agagtgcgaa caatagataa gtccggacaa tcagcaagct gtcggccgca
    21601 tattttccta tatattgggg cagattattg cggaaagcag ctgttttcat ttcccagcag
    21661 ataaggacac cctgaatcag gccgtatatg gcgaaagtca atccggcccc atgccacaaa
    21721 cccaatgcga gaaaggtgat gaggaggctg aagtagattc cccactgtcc ccagttacgg
    21781 gtaccggcgg ttagcggtac atagagataa tcgcgtaccc agaaggagag tgacatgtgc
    21841 caacggcgcc agaagtcggc agtcgagcgt gctgcaaacg ggcggttgaa gttgggcgac
    21901 aacttgatgc cgaacatata ggcccctccg atagcaatat ccgtataacc cgaaaaatcg
    21961 gcatacagtt cgatagggta gagtaggcaa gtcattagca gttgtacacc cgagaggtca
    22021 tggatcgaat gaaacatgac atctgtttgt ggggagatct gattggctat cagcagtttc
    22081 ttgatcagtc cgagtaaaat atatttcagt ccggtcaccg cgtttgagta gatgaacggg
    22141 cggggatctt tcaattgtgg caacaggtct ccaccccgtt cgatagggcc ggagagaaac
    22201 ttcatgaaga aaagcatata gatcaggaaa tccacccagt ttctttcgct gcgttgctct
    22261 tgccagtaca cgtctgtcag ataactgatg gcttgaaatg tgtaaaatga catcccaagt
    22321 ggaaagatga tatcatctat gaccgtgcca tgaagaagaa gccatccgcc gatcagggcg
    22381 atgattcctg cgatatagac gggtttggtc ttttttccgg cttttgccct gctttccatc
    22441 cattgtgccc aaaagaaggt gaacagtgct accactactg ccgtcaacag gaaaggcaga
    22501 tagtaccatc cgatgaaaat acaactggtt accagtagta tgaggttgcg ggcacggcct
    22561 ttgactgcat agtagaggaa gaaacagagg gtaaacaggg ccaggaaact aaaagagagg
    22621 aactgcatcg tttattccat tttggttaat aaggcactgc acaaatcgcc gacattcttg
    22681 aacttaatga cctccctgaa attgaaacgt actccgaaat gtttctcgat ttgagctata
    22741 atttgcatgt gggttagcga gtcccagcca tctacatctt ttgaggtaga tgattcgtcg
    22801 atacatacgt tgtccttttt taagatatca cggaaaatgc tttgtagttg ttttaatact
    22861 tcttctcgat tcatatttat tattgttttt agagtttctt ctcttttatc agttcggcaa
    22921 tctttttacg gtctgtttta ttactattgg tcaccggaaa ttgggaaata caatgaatct
    22981 gcttcggcag catgtatttg ggcagctttt ctttcagata ttctatcaat gcgctttggg
    23041 tacattcagt tgtctcgacg gccagatgta attcgttaca gattccgtcg cagagcaacg
    23101 gaacggcagc cacgctgcag ggagtcttga aaaacgactg ggcagtatat tctatttcac
    23161 tcagttctat cctgaaaccc tgtattttca cctgatagtc tttacgtccg caataaataa
    23221 tatccccgtc gccatccaga atacacaagt ctccggtccg gtaatagatt tgtccgtcgg
    23281 gacggtgtat cagaaccaat gccgattttt ccgggtcgtc cagataacct ttcattacct
    23341 gccggccgga tacccaaagt tctcccgtct ctccttgagg tagctcgttt ccttcttcgt
    23401 cggcaatgat ggcgcggatg ccgggaaatg gttttccgat agccaccatt ccgttgtaat
    23461 gcttgcattt gtccgaagcc ggaatacggt aacaggtgca gtaaatcgta gcttcggtcg
    23521 gtccgtatag gttgatgaac gttgcgttgg gtgccgattt tctgaatcgc tccaacagct
    23581 cggtttgcga tgcttctgcc gatactccca gatatttcag agagggcaga ttgatttcgt
    23641 cgaagtaggg tgaaaggagt tgtagcagtg agggagtgac agtggcaaag gtcagttgat
    23701 acttctccag aagttcaaac accttgaagt gctttacatc ctgatggcct accgtataaa
    23761 cggcagcacc taaagtaaga ggatacagta aagatactac ggatacatcg aatgtaagtt
    23821 cgaacatttg caacatgcga tcatgttcat ccagattcca gtcgagcgaa ctgtatgccc
    23881 ggtaaaaggc gttcaagtta gcccgtgtga tgggcactcc tttgggctcg cctgtgcttc
    23941 ccgatgtaaa aatgatataa gcgttccttt cttcgtccga tgaatgggac tgctgttctg
    24001 acagtgtttt tcccggtagc cggtccgtat cgatgattct gaagtgtccg gtgccgaatg
    24061 ctgaccggtc agtgtcactt gtacagagca aagtacgcag tccggccaga gcggctattt
    24121 tgagattacg ctcttccggg taggcaggat gcaggataac ataggtcttt ccgccggcta
    24181 gtactgccag aatagcagca taggtttcaa tccggttttc cgctacgatt ccgatttttt
    24241 catcttttat ttctgatagc gaatgggtga tagaagctgt tatttcaccg agttgggcat
    24301 aagtataatg tttatcgtca ataatgaatg cttcgttttc gggataacat tgcatggcgg
    24361 aaagaatatc attgataata tccttctggg aagatgttgt catatccatt agtttttatt
    24421 catgttttgg gtttaggggt tctttatata tcttcttgag atcgtttatt aagatgacag
    24481 tgaaatggtc tgatctccct acgcacaatc gattaaagaa tgttaattat gtggtacgca
    24541 cgtgcccggt ctcgctttcc ctctttcgga aggggaaata gcgttggctt catagccgac
    24601 gactttgaat gggatagaca acacgatact ttattgata
//
