LOCUS       c00030_gnlPro..        13346 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GOGHGBIN_30.
ACCESSION   c00030_gnlPro..
VERSION     c00030_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:41:25
            Original ID  :: gnl|Prokka|GOGHGBIN_30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13346
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13346
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[387:3346]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      388..3346
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13346
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13346
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(185..298)
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MLNSIKIPIYGEKLDSSYYFQIYFSNIFLRNNLQVKK"
     CDS             388..2616
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_2"
                     /sec_met_domain="Gly_radical (E-value: 3e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1165.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYITVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2621..3346
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.9;
                     E-value: 1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_3"
                     /sec_met_domain="Radical_SAM (E-value: 4.3e-30, bitscore:
                     97.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEKGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3579..4841)
                     /locus_tag="ctg30_4"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVMDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4893..5441)
                     /locus_tag="ctg30_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5629..6381
                     /locus_tag="ctg30_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6486..7484)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg30_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.3e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7554..8027
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILATYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8131..9129)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.9e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9184..10452)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_10"
                     /sec_met_domain="MFS_1 (E-value: 5.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10702..11715)
                     /locus_tag="ctg30_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSIADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11738..12895)
                     /locus_tag="ctg30_12"
                     /transl_table=11
                     /translation="MTLKNLIMKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLN
                     EASENGSAKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVL
                     PEQYFTYDKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSK
                     FIILLDKPLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSG
                     SSDHEVYIRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYING
                     VLDVTLQTKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPA
                     DPNLIGYWKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 taaaaaaggg tgtaaatctc gcaaatgctt gatttacacc ctttattgcg gagagacagg
       61 gattcgaacc ccgggtacct cgcagtacaa cggttttcaa gaccgccgca atcgaccact
      121 ctgccacctc tccagaacta cggttaagta gtgcttttct cttaaagcgc tgcaaaggta
      181 cgaatcattt tttaacttgc aaattattcc gcaaaaaaat attagaaaag tatatttgga
      241 agtaataact gctatctagc ttctccccat aaataggtat ttttatgcta ttcaacataa
      301 aataggaccc ttttatatac ctaaaccgaa aaaaggttgt aaatttgcgc gctctaaagg
      361 ataactaacc actaactgat taattttatg gaactgaata agacctttaa agatggactt
      421 tggagcaaag aaatcaatgt aagggatttc gttagtaaca acatcactcc ttatgaaggg
      481 gatgcttctt tcctgcaagg acctaccgaa cgcaccaaag ctgtctggaa tcactgtctc
      541 aaagctctcg aagaagagag aaacaataat ggtattcgtg cactcgacta cataactgta
      601 tctactataa cctctcaccc tgccggctac atcgataaag agaacgaact gatcgtcgga
      661 ctacagaccg atcaggtgtt aaaacgtgcc atcaaaccgt ttggcggaat caatgtggtt
      721 atgaaagctt gccgtgaaaa cggagtggaa gtagatgaca gagttaagga tatcttcact
      781 cactatcgca agactcataa tgatggggta ttcgatgtgt ataccgaaga aattcgttcg
      841 ttccgttcat tgggattcct taccggactt cccgacaact atgcacgcgg acgtatcatc
      901 ggtgattatc gccgcctggc tctctatggt cttgaccgtc tgatagaagc taaaaaagaa
      961 gatctgcata atctgacagg tcctatgact gaagcccgca ttcgtcttcg cgaagaagta
     1021 gccgagcaaa tcaaggccct gaaagagatt aaagtattgg gcgaatatta tggtttggat
     1081 ctgagccgac cggcatatac cgcacaggaa gctgtacaat gggtgtatat ggcttatctg
     1141 gctgccgtaa aagagcagga tggtgctgcc atgtcactgg gtaatgtatc ttcattcctc
     1201 gacatctatc ttgaatatga attaagccag ggtacgataa ccgaaacatt cgctcaggaa
     1261 ctgatcgacc aattcgttat caaactccgt atggtacgcc acttgcgtat gcagtcgtac
     1321 aacgatattt ttgcgggtga tcccacatgg gtgaccgaat ctatcggtgg acgtttcaat
     1381 gatggacgta ccaaagttac taaaacttct ttccgcttct tgcagacact ttataactta
     1441 ggcccgtcac cggaacctaa catgactgta ctatggagcc ctgagttacc cgaaggtttc
     1501 aaagcattct gtgcacaagt atctatcgac acttcttccg tacaatacga aaacgacgac
     1561 ctaatgcgtg aagtccgtca atcggatgac tacggaatcg cttgttgtgt ttcatatcag
     1621 gaaatcggaa agcagattca attcttcggc gcacgtgcca accttgccaa agccctgcta
     1681 ctggctatca acggaggacg ttgcgaaaat acaggtacag ttatggtaaa agacatccct
     1741 gtattgaccg gtgaaacact gaagttcgaa gaagtaatgg ccaactataa gaaagtattg
     1801 atacaaattg cacgtgtata caacgaagca atgaatatca tacattacat gcacgataag
     1861 tattactacg aaaaggcgca gatggctttc gtggatactg atccccgcat taacctcgct
     1921 tatggtgtag ccggactctc aatcgccatc gattcactgt ccgccatcaa atatgcacat
     1981 gtgaaagccc gtcgcaacga catcggactg acggagggat tcgatatcga aggtgctttc
     2041 ccttgtttcg gtaatgacga tgaccgtgta gaccacctgg gtgtggacct ggtatatttc
     2101 tttagcgaag aattaaagaa actccccgta tataagaatg cccgtcctac cctctcgctg
     2161 ctgactatca cttcgaacgt aatgtatggc aagaagaccg gtgccactcc tgacggacgc
     2221 gccaaaggca ttgcctttgc tcccggtgcc aaccccatgc acggacgtga taaaaatggt
     2281 gcaatcgcct cactgagttc tgtagccaag ttgcgttatc gcgactcaca ggatggtatc
     2341 agcaatacat tctcaatcgt tcccaaatca ttgggagcaa cacaagaaga ccgtatcgac
     2401 aatctggtga ccatgatgga cggatacttt acaaaaggcg cacaccacct gaacgtaaac
     2461 gtgctgaacc gggaaatgtt gcaggatgcg atggaacatc ccgaaaagta tccgcaactg
     2521 actatccgtg tctcaggata tgccgttaat ttcgtgaaat tgagccgcga acatcagttg
     2581 gaagtaatca gccgcagttt ccacgaaaga atgtaattga atgataaacg tacactcata
     2641 cgagtcaatg ggaacattcg acgggccggg tctccggctc gtcgttttcc ttcaagggtg
     2701 taacttccgt tgcctctatt gtgccaatcc ggacacaatt gaagccaaag gagggacagc
     2761 aaccgaccct gaggaaatag ttcgcatggc cgtcagtcag aaagctttct tcggtaaaaa
     2821 gggaggtatc accttttccg gcggagagcc tacttttcaa gctaaatcgc ttatcccact
     2881 ttttaaaaga ctaaaggaaa aaggaatcca tatttgcctt gataccaatg gcgggctatg
     2941 gaacaatgat gtagaggaac tattggaatt gactgatctg gttttattag atatcaaaga
     3001 atttaatccg gaacatcatc agtctttaac cggaagaagc aacgagcaga ccctgaaaac
     3061 cgcagcctgg cttgaaacca atcataaacc attctggttg cgatatgtat tagtgcccgg
     3121 ctacagtgac ttcgaagacg atatccggca actgggagag catcttggaa cgtaccagat
     3181 gattcagcgt gtagaaatat tgccttacca caccttgggt gttcacaaat atgaagcaat
     3241 gaacaaagaa tatatgctga aaggagtgaa agagaatact ccggagcaga tagaaaaggc
     3301 tgagaaacta ttcaggcaat acttccggac cgtacaagtg aattgactta tataagtgtc
     3361 gaaattcgta ttcgccacag attacacgaa tttacacaga taaagattca ttggcaatca
     3421 acagattaag ttcactctgc ggtgaattat gacgattgcg cttatttata attttgtaag
     3481 tcacgacata aaaatctccc tgttcttgcc tcaattcatt acaatacaag gcaagaacag
     3541 ggagataatg taaccggcat attttttgcc accctacttt aataagtgaa tcgcaatcct
     3601 gcctgcaagt taaagttaca aggcctttct tttcggatgg tttgtacttt ggagccatca
     3661 tcaaagaaat acgaaactcc cggttccaca tataggccga catgatctgt cgcattgaat
     3721 tgcgctccca cggcaccggc tacagaaaat tgcaaaggct tcacattcac cttatcatcc
     3781 gccaactttc cataaacaca cttttcaacc attcctccgg cagatacata gagtgtaaaa
     3841 tatttctttt ccagaaaatt ccagtttcca cgtacaggaa tacctatata atgcaatttc
     3901 tgactctgca tcttggtatc cccctgccgt ttgatgtcag aagacaacaa cgtataagtc
     3961 aatcccgtct ctacagagaa acctttggga agagacttac gtacagacag tccgaagcta
     4021 accggctgat gatgttcata atccatcacg gcagttgtat tggacttcag atagggaacc
     4081 ccttcttcaa atataacttc ctgatcggca ggaatactca cagctccatt catgatcgtc
     4141 atcaagtcga ccctgttagt catcggacgg ggcgcaaaat tttcggaacc atttgtcgga
     4201 agtccacctc cattaccgat acccactccc atcgaccatt taccaccacg tttagcagaa
     4261 gagtctccga taggcaactg atacttgtct ttaccggacg gtcgccgcgc ttctttcctc
     4321 tttggaggct gcgccgtcgc actttctttt ttctcgattg cagcaattgc ttcctgttgc
     4381 ggctcagatc tcttttcctc cgtcactgcc tccggtcgct tctctaccag ggaggatacc
     4441 tccggaacaa tcaccggatc agtattcttt gccaaatagc ccgaaacagg gttaatactc
     4501 gtcgttccta ccggcttaac tggttcggat acagctacct gtacatccgg caaggcaggt
     4561 tccggcaata catccgggtt gacagccagt gaaggagccg ttgcataacg gatttcatca
     4621 gctaccggac tattcagaaa atacaaactg acagcagtcg ttagcaccaa taccacagct
     4681 gccgcagcaa ccgcccaccg gcgatacgga tatattcgtt tttcggttac aggcatcagt
     4741 tccctttcca gtcgttccca accggaagca ggcatcggct ccgaataatc ttcgagctta
     4801 tccttgaatg ctttaatcca tttttcgtct tctttcatca ttctatttca tttttgaaat
     4861 ccaaggttca cctcagtatc tgtaaataca tgtcaaccat tggtcaccaa ccattctttc
     4921 actttctttg ccaatacact ttttgcgcga aaaagctgtg aggcagaaga tttttcatta
     4981 atccccaaca tctgtgcgat ttccttgtgc gacttatctt caaaggtgta taaattgaat
     5041 acggtacgat atccggcggg gagttcatta ataaattgca tcagcacttt ctgtggtatt
     5101 gcttcaacag ccgaagcatc cggttcttca tacgtttcgg gaacttcatc cagtgccgtg
     5161 gtctggttca tcacgtcgtt ctttcttaag aactgtaaag ccgtattcac cattacacgc
     5221 tccatccatg ctctcagaga gccttcaccc cgccaggtaa acttgtcgaa ggagtcgaaa
     5281 atcttcagga aaccgtcgtg taccaagtct tgtgccatgt ctctgtctcc ggcataacga
     5341 agacagacac caagcatgcg ccctgcgtac tgctcataaa gttctttgcg ggcacgatta
     5401 tctccctgcc tgcaacgttc cgacagctct aattcattca ttctcctaaa cacgtgttta
     5461 ccttataaat gcagcaaaga tagaaatact gcacagagag aacaactctt ttatcacttt
     5521 tgtttcttta acattttagg atgcaatatt tcatcacttc ctgcattttc tcaatacaat
     5581 aaagaataaa tctcaatgga taaataggat aaaaccaaca agaaacttat gaagaaattt
     5641 aatttaataa cttttgccgt catcctgatg ttattgccca tattacagtc atgtctggac
     5701 gatgccaaca acgacgagtg ggtcacttgt cctccgggtg gaatattagc catcggcaca
     5761 atgaagattc ccaatgcgga cactccaagg gactttttca ttgcgttgga caatggagac
     5821 aatgtacttc cggcagatac ggccgatata cgcaacagga aatacactgt tgcagaaggt
     5881 caaagagtct tcgttggcta tctgcagatg ggagaagaga aacccggata tgagaacggt
     5941 aaaatattca cgatagaaga tatattgacg aaagagatca tcccactgac ggaagctaca
     6001 gcagacagca ttggagacga ccgtatcaac gtcacagcgc atgcacttac gaaagattat
     6061 ctgaccatcg aatatcaata tctgggcagc atgaatgaaa ataaaaaaca catgctgaac
     6121 ttggtacaaa acgaaataac aggtcccata aaagatgacg gatatatcta tctggagttc
     6181 cggcataatg cctttaatga ctcccccaat caattgggtt cgagccttgt ttctttcaag
     6241 ctggatagta tagccgagca attggcgaca gccaaaggaa taaaactccg tgtgaacacc
     6301 atttatgaca atatacagta tgtcacaata gatatcaacg aagacaaaaa cttaaaaata
     6361 aaatcatttc attctcaata aaacaacaag aaacacctac acaatcaggc aaaacgagta
     6421 ataattctga tacataaaag aaataaggcg gcgatgtttg tgaaaatatc gccgtcgttt
     6481 ttatattata ccagacactg aacggcctgc agggtaagca tctccttggg aaccgccgcc
     6541 tgaatctcct ctttcaaaac ctgcagcaga ctggtgcgga tgaagtcttt ccgggtcacc
     6601 aggacaatct gacgggtagg ccgcgggata gcaaacggac ggaccagttc tttctgctct
     6661 tcgctcaatt gcatcactgc cagttcggga ataaacgtaa tccccttacc actctccacc
     6721 atatgcataa aggtttccat actacccagc cgatacgcca tttggctgat cttaaccgct
     6781 tccatctgac aaaaacgaac caactgatcg cggaagcaat gcccttcgtc aagaagccaa
     6841 agccgttccc ctgtcacatc ggacgtacga atcacatcgt gcttgaacaa cggttccttc
     6901 tttgagacat agcccaggaa ttgctcgtag aataaggtct cttccgttaa tgcggcatca
     6961 tccagcatgc tggcaatgat agcagcatcc gcttcaccgg tcagcagagc cttgcgaatg
     7021 tcgggcgtct tcatctccat cacccgtata tcaagatccg ggtatttctc catcagttgc
     7081 ggaaagaaac ggggcagaag ataaggtgca atcgtcggta acactgccaa tcggaatgta
     7141 cccgacaggg agtgctgttc ttcgctgatg atctccttga cacagataac ttccgaaaga
     7201 atcttacggg cctgttccag cactttctta ccaatggcag tagggcaaac cggtgtcatg
     7261 ctacggtcga acagtttcac ccccaattcg tcttccagct tttggatcat tgcactcaaa
     7321 gtaggttgcg tcacccggca atactcggca gctttagcaa aatgccggaa ctggtcgaca
     7381 gccagaatat attccaattg ttgtatagtc atcgttctct gatttattaa agatatagaa
     7441 tctatcaatg caaagataga aattttcagt ttgacacgaa tcattttgtg ccgtatcttt
     7501 gttccagata aaaagaagaa atatagtatt aactcaaaaa aaacaatatc attatgaaga
     7561 ctttaaatta tacacatttg gaagaaaaag gagctaacac catcgtactg tcattacagc
     7621 aactgcttgc cgattttcag attcattatg caaacctgag aggatttcac tggaacatca
     7681 aaggacacgg tttcttcgta ctgcacagca agtttgaaga tttatataat ggagccgccg
     7741 aaaaggtgga cgaaatagcc gaacgtatac tgatgctggg aggaactccc gccaataaat
     7801 acagtgacta tctgaagatg gcgcagatca aggaagtgga cggagtgaat aaggccgacg
     7861 acgccctgaa tcatattctc gcaacttacg ggcatctgat tgcggaagaa cgtaaaatcc
     7921 tgtctctcgc ctcttcacac aacgacgaag taacagtggc catgatgagc gactacctga
     7981 aagaacagga aaagatggtt tggatgctga ctgcatacaa cggataacag ccgaaagggt
     8041 gtagccatct gaccgaaaag gtgtagccat acaagcaaaa gggtgtagcc atcccggcgg
     8101 gatagctaca ccctttctgt tttattcgat tcagatgata cttgtacgtt tggtaaattc
     8161 aataatctcc ggaatgtatc cgaatgcgag cccggtcact gtatccgcac acccataata
     8221 gatggcaatc cgtccggtct ccgaatcatg aagcgctgcg catgggaaac agacattagg
     8281 cacatcaccc atacattcgt aatccttctg aggtgaaatc agataaggcc ccgaacggaa
     8341 ttttactttc cagggctgat cgatgtcaag cagtgccgaa ccaaaactat acacaaaacc
     8401 gttgcaggaa gccaatacac catgatagat cagtaaccag ccttccgagg tttcaatcgg
     8461 gataggccct gcaccgatct tggtacactg ccaggcactg tcttcgaacg gagccggcga
     8521 cataacatga cgatgacgtc cccaaaactc catatcggga gactcgctat agaaaatatc
     8581 tccaaaagga gtatgcccat tatcactcgg gcggctcaac atcgcaaaac gaccgtttat
     8641 cttacgaggg aacaagactc cattccgatt gaagggaata aaggcattct ccaactggtg
     8701 aaaagtaaca aaatcatagg tgtaggccac accgatagta ggaccatgat agccattaca
     8761 ccaggtcaca tagtagcggt cttcgataaa gcaaacccgt gggtcatatc catagaccca
     8821 ggttccaacc tcagcgtcat cacattgaaa ctttaacggt tcttcgttga tatcccaatg
     8881 aacagcatcc ttactgaatc ccacatgcaa acgcatgcga cgattagtat catcacaacg
     8941 gaacacccct gcatagccat ccttaaacgg aactacggca ctgttgaata tactgtttga
     9001 agtagggagc aagtcgcgcg gaataatcgg attggccgaa caacgccaca ctacatcttt
     9061 acatcctgcc ggacgttctt cccaaggcat agccggcaaa gcagcacctg caattttaat
     9121 ttcttccatg attcgattaa attaatatta tgtatatatc ttgtttatat tgaaaatctc
     9181 tttttatttc ttctttccgt ccggatatgt gaaaggtacc agccaagtca cgataaaagc
     9241 cggtatggta gcgataagta cccagataaa gaaatcgcga taacccagcc aatcgctcag
     9301 gtatccgctc atcattccgg gaagcatcac ccccagattc ataataccgg tagcaaaagc
     9361 ataatgtgcc atctgatgtt tgccgggagc cacttgctgc atcataaaga gcatcaatcc
     9421 gacaaaacca aacccgtaac ccaagtattc agacacaatg gccataccaa taatccatag
     9481 atcggaaggc tggtaaaggg ctaacaggaa atataccaag aacggaatat taaaagcgca
     9541 acataaagaa aacaaagtct tccgaagtcc gaaagccgaa atgtaataac cggccaaaag
     9601 cgaaccgaga ataaaagctc ccgctccgaa cgtaccatat accagtccga tatcctgagt
     9661 gctgagtccc aatccaccat ccgcaaccga cgctttcagg aacaacggta caatcttgat
     9721 ggcatatcct tcggcaaacc ggtacaaaat gataaagaca atgtagaaag caatatgttt
     9781 tttttggaaa aaagagcgga tgacttccca aagcatattc aatgcgtcac tcatcgtatt
     9841 cacttcaccg gaagcgcctc ctcccgaagg caaaatccgg atgtggtaaa gaccgatcag
     9901 aatcataata cccgcacaca tcaacatgac aatcatccag gcatgtacca ctccaaattc
     9961 atccttcagc atacctgcca gccaaaccaa gcctccgttg gcaagtatct tagccagatt
    10021 ataaaaagct ccctgccaac cgatatactt ggcttgctgg gtagcagtca gttcagtcag
    10081 gtatactccg tcacccgcaa tgtcatgagt cgcaccactg agagcaatga tccccatcag
    10141 agcgatggca taacgaaaaa agtcgggcag cggcagcgaa agtgctacca atgcaaatgc
    10201 cagtccggta atgatttccg tagcgacaac aaagtatttt ttcgttttaa acatttccag
    10261 aaacggactc cataaaggct tcaatgtcca gggaagcata atgagagaag tccagaaagc
    10321 aatctgtgca ttcgacactt ccatatcgga aaacataagg acagaaacca tcgaaagggc
    10381 cacaaacggc aatcccatag caaagtaaac agtaggcacc caacatacag ggcttatcgg
    10441 ctttttattc atcagttagt tttttataat aattccatcg gttaacaatt ccagtaagca
    10501 aagatagggg atattaaaaa cataacccaa gattacgaca agaagttgct ttcattattt
    10561 aataatacaa ctcacccggg aaaactacta acctctatca cccttttttt attaaacttt
    10621 atcaatacaa tacacgcaaa gaagcaccga agactttcat ccccgatgcc tctcgccccc
    10681 ttatctacaa tctaaacacc tctattgctt cacatataaa tttatctcag caaacccggt
    10741 ataattatcc ggagtcagac agtttattct gaattccttt acattcggga taggtggttc
    10801 gatggccgca tattgcggat cagccccttt aaaatttctg aaagtcaaga ctctcgggta
    10861 agtaacccac tcggtttcac cctctttccg aaccttaatc tcagcacttc tcaggttata
    10921 acccgatccg taggcactct gtttagtgac cgaaaatccg gttaaggtaa caggccggtc
    10981 cagtaccgta ttccaccaac actctccggc attagccact ccccatgtaa accaagtagt
    11041 atttatctca ccgtcaatag ccagatgtgc accatattta gcatcatcat cggcataaac
    11101 attgctgcaa cttacactcc acgcacttcg atctacagcg gaccaattcc cgggtttcgt
    11161 ataactggta taaagcacgc tggtataaat ccggatataa accgtcttca tagatgtact
    11221 gacagcctgt tcgtccatgc ccgtaactcc tttaagcgtc acgggaagca catatccgtc
    11281 aggattagtc aacttttcta tattcttcaa aacgacctga aaagatgaat cggccactgt
    11341 ctgtcccgtt tttaagacaa cttcacttgt ttcaatggta taattatctt ggggcaacaa
    11401 cttacatttc gtcttattgg cagaattgta agtatccact ttcagcgtat ctactcccaa
    11461 agcggcagtg acatcccgcg taaccggctg tacggcacac aattgtattt caaaatcaga
    11521 acggtcggca atagaggaat tgctcacaca atccaccact accgcagcac ccatttcggc
    11581 ccccggtgca actcccgttc tgatatatat cttttgatat ttgtccattt catcatcatc
    11641 gttgctgcac gaagccaacg atacaaaacc tgttatcagg cagattaagg tcacaaaatt
    11701 caaatgtcta ttcatatctt atcttctttt tacatagtta ttgcttatca aaacgaacat
    11761 gctctttcca gacaagagtt cctcctgcca ccaaatcgta tccgtgtccg gtacagtcga
    11821 caaaggcatt tcccttacct tcatccattt tccaatagcc tatcaggttc ggatcggcgg
    11881 gcttcacggc aaaatacatg ttggactgaa tttgcgtctg gctgattgcg ctcttccaaa
    11941 gacgcacctg ggccatctga caattgttgc ggaagtagct accgctcgaa accatgttca
    12001 tcttgtcgaa tcttaccgga ccaccctttg tctgcagagt cacgtcgagc actccgttga
    12061 tataaatcga caataacccg gaagaattat aaacgaaggc cagatgatac cacttattct
    12121 tctcaaacaa agtcaccgta ttgacctgac ttccaagtgt cttcacctgt aatgaattat
    12181 aagggatcat agcgtcaccg aaacggatat aaacctcgtg gtcgctgctg cccgaattaa
    12241 atatagcctg attattaata tcgaatccgt ccatctgtac ccaagcctcg agtgaccatt
    12301 cattggttgt cactccccac aattcgtcct tggcgggctt cacggcattg gtcgtattca
    12361 taaacggtac agactgtatc agcggcttat ccagcaaaat gataaacttc gacgaaagcc
    12421 cgattgtgga caccggtccc tgaatttctg tgagagatac cggaatagca tacaattctc
    12481 cgttttcgtt tgaataaggt ttcactctaa actcactggg gattgcgcta acatcgcctg
    12541 ccgctatctt tatctctttg tcataagtaa aatactgctc gggaaggact tcgtacgaag
    12601 tttcattagc ttcattgtac tctttaagaa tagaaggatc taccgtcagg acagcagtca
    12661 cattttcggt tacaggctgt cccacacgta cggtcagagt agttgttgtt acattttcag
    12721 gatcaacggt aacctttgcc gaaccattct cggatgcttc attcaaataa atcgcattgt
    12781 cgataacctg gtaatcggca tcgttgcatc ctgccaggat catcggcaga acgaaacagg
    12841 caagcaaata ttgttttatt gttattcttt tcataatcaa attctttaaa gtcattttac
    12901 agcaggattc attattctga ttgcttcacg caggtactta tattcgatgt cgcccggata
    12961 gtcatattcc atgtgatagg tgcctactcc acccttccgt acctgttttc cgtcaatagt
    13021 cggagtccag cgtgccatgc cggcaagtgc tctcattttg tttccgtaac gatctacata
    13081 atcacctcct cctgtcggag cataagattc gaaattctcc gtaacgatgt acatattagc
    13141 cactttctcc ggaggaagta ttcctttaaa gttggcaatc gtaccagcca gacgtctgtc
    13201 aagattagca tcggaattac ccgcaaggtt agagtatgcc tgcacaatga aatagtcaaa
    13261 gtaaggcccg gtttccggat gaatactttg aggctcgcca tcaatcacaa gtaaccgtcc
    13321 cgtacccgat ttaggtccga ttcttt
//
