LOCUS       gnlProkkaDMKNCOBH_276  16210 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DMKNCOBH_276.
ACCESSION   gnlProkkaDMKNCOBH_276
VERSION     gnlProkkaDMKNCOBH_276
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 13:33:44
            Original ID  :: gnl|Prokka|DMKNCOBH_276
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 29004
            Orig. end    :: 45214
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16210
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16210
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16210
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2027..3064
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg276_19"
                     /sec_met_domain="PF04055 (E-value: 2.6e-17, bitscore: 54.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSKYPLLGMTLIELQSLVKRLGMPGFAAKQIASWLYDKKVTSID
                     EMTNLSLKYRELLKQNYEVGAEAPVEEMRSVDGTVKYLYPVGENHFVESVYIPDDERAT
                     LCISSQVGCKMNCKFCMTGKQGYSANLTAHQIINQIHSLPERDKLTNVVMMGMGEPLDN
                     LEEVLKALDILTGSYGYAWSPKRITVSTVGLRKGLRRFIEESDCHLAISLHSPVTAQRA
                     ELMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCR
                     INLIRFHSIPGVALEGADMDMMTRFRDYLTTHGLFTTIRASRGEDIFAACGMLSTAKQE
                     ENNKS"
     CDS             3082..4119
                     /locus_tag="ctg276_20"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKGNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFDCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTREA
                     EPTNK"
     CDS             4124..5218
                     /locus_tag="ctg276_21"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5342..6583
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg276_22"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6570..7097
                     /locus_tag="ctg276_23"
                     /transl_table=11
                     /translation="MNWIKKIARPLILVVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7102..7875
                     /locus_tag="ctg276_24"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQLAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7882..8277
                     /locus_tag="ctg276_25"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             8568..9956
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg276_26"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             10001..10348
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg276_27"
                     /sec_met_domain="PF05402 (E-value: 3.2e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-09, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10338..10625)
                     /locus_tag="ctg276_28"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10647..11711)
                     /locus_tag="ctg276_29"
                     /transl_table=11
                     /translation="MKKFIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(11785..13296)
                     /locus_tag="ctg276_30"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTSEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQAGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             complement(13762..14595)
                     /locus_tag="ctg276_31"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             14868..15092
                     /locus_tag="ctg276_32"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             15285..16208
                     /locus_tag="ctg276_33"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFF"
ORIGIN
        1 cgacgaagta tggcgttcct acgttaataa caaactggtt gagaaagaag caaaagcatt
       61 gggactgaca gtctctgctg ctgaaattca ggatatcctg aaagcaggcg tgcatccgtt
      121 gttgcaacag actcctttcc gcaacccgca gaccggtgct ttcgataagg atatgctgaa
      181 taagtttctg gtagattacg ctaaaatgaa cgaatctcag atgccggctc agtatgcaga
      241 acagtacaac aacatgtaca aatactggtc attcatccag aagacattgg ttcagagccg
      301 cctggcagaa aaatatcagg cattggtagc aaaagcgctt ctctctaacc cggtagaagc
      361 acaggacgct ttcgacgcaa gagtgaatca atatgacttg ttgatggctg ccgttcctta
      421 ttcttctgta gtagattcta caatcgttgt gaaagaatcg gaactgaaag acttttataa
      481 caagaagaaa gaacagttca agcaatatca ggaaagccgt gatatcaagt acattgatgt
      541 tcaggtgact gcaagtgcgg aagacagagc tgctatccag caggaagtag acgaagctac
      601 tgcacagctg gctactacaa cagatgatta tacttctttc atccgttctg taggttcgga
      661 agctccttat gtagacttgt tctataataa aacagctttc ccgtcagatg tagttgcccg
      721 tctggactct gcatccgttg gttctgttta tggtccgtac tataatggtg ccgacaatac
      781 tattaattca ttcaaagtgg ttgcaaaaac agctgctgcc gactcaatcg agttccgtca
      841 gattcaggtg tttgcagaag acgctttgaa gacaaaagcc ttggcggaca gtatctatac
      901 tgctatcaaa ggcggtgcta acttcgcaga tctggctaag aaatacggtc agacgggtga
      961 gactaactgg atgagctctg cacagtatga aggcgcacag atcgatggtg acaacctgaa
     1021 gtttatctct gctatcaata atacaggcgt gaacgaagta gtaaacctgc cgttgggaca
     1081 agctaatgta atcctgcagg tgactaacaa gaaagctgtg aaggataaat ataaagtagc
     1141 tgttgtgaaa cgtgaagttg aattcagtaa agaaacttat aaccgtgctt acaatgactt
     1201 cagccagttc atcgctgcca atcctactgc tgaaaagatg atcgctaacg ctgaagaagc
     1261 cggatacaaa ctgcttgaca gaagagactt gtatagctca gaacacacta tcggtggtgt
     1321 aagaggtact aaagaagcat tgagatgggc atttgccgct aaaccgggtg atgtttccgg
     1381 tttgtatgaa tgtggcgaaa gcgaccatat ggttgcagta gctctggttg gtgttactcc
     1441 ggaaggatat cgtccgctga aagctgtaca ggatcagttg agagctgaaa tcgttaaaga
     1501 taagaaagcc gaaaagatca tggctgatat gaaagctgcc aatgcaactt ctctcgacca
     1561 gtacaaggct atgcccggcg cagtcagcga ttctttgaag ctggttacat ttgccgctcc
     1621 cgcttatgtc tctgaattgc gcagcagcga accgctggta ggtgcttatg cttctgtggc
     1681 tgaaatgaac aaactgagtg ctccaatcaa aggtaatgcc ggtgtatttg tgcttcagat
     1741 gtatggcaaa gacaaactga gcgatacttt taacgctaaa gatgaagaag ctacattggc
     1801 taatatgcac gcacgcttcg caagccgtct gatgaacgat ctgtatctga aaggaaaagt
     1861 gaaggataca cgttacctgt tcttctaaga ttagtcgtaa aaacgataac tgcaaaaggt
     1921 cgttccatgc tttggaacga ccttttttgc taacttttac atccttgcta tacggaaatc
     1981 gactttattt ccttacattt gcaaatataa accatgaaca gaaagaatga tgtctaaata
     2041 tcccctctta ggaatgacgc ttatagagct gcagtcactg gtgaaacgtc tgggaatgcc
     2101 gggctttgca gccaaacaga ttgcatcctg gctttatgat aagaaggtga cttcgattga
     2161 tgaaatgact aacttgtcgt tgaaataccg ggagttactg aagcagaact atgaggtagg
     2221 agctgaagct ccggtggagg aaatgcgctc tgtagacggt acggtgaaat acctgtaccc
     2281 tgtgggcgag aatcattttg tggagtcggt gtatattccg gatgatgaac gggcgacttt
     2341 atgcatttct tcgcaggtag gctgcaaaat gaactgcaag ttctgtatga ccgggaaaca
     2401 aggctactct gccaacctga ccgcccatca gattatcaat cagattcact ccttgccgga
     2461 acgggacaaa ctgacgaatg tcgtcatgat gggaatgggc gaaccgctcg ataatctgga
     2521 agaggtgttg aaggcattgg acatactgac agggtcctat ggttatgcat ggagcccgaa
     2581 gcggattacc gtttcaactg tcggattgcg gaaaggattg cggcgcttta tcgaagaaag
     2641 cgactgtcac cttgccatca gcctgcattc tccggtgacc gcccagcgtg cggaactgat
     2701 gccggcggag aaagcctttt ctatcacgga aatggtggaa ctgttaaaaa actatgattt
     2761 tagcaaacag cgtcgacttt cgtttgaata tattgttttt aaggggctta atgattcgca
     2821 agtttatgcc aaggagttac tcaaactgct tcgcggactg gattgccgga ttaacttgat
     2881 ccgtttccat tctattccgg gagtagccct tgaaggagcc gatatggata tgatgacccg
     2941 tttccgtgac tatctgacta cgcacgggct tttcactacc attcgtgctt cgcggggaga
     3001 ggatattttt gcggcatgcg gtatgctgtc gactgcgaaa caggaggaaa ataataaaag
     3061 ttaatataaa aatcgaacat catgaaaaag tacttttttt atttaagcat ggctctggta
     3121 gccttcgtag ttgcttcttg tggattaaag gggaatcata cctctagcgg tcgtccgtat
     3181 gaactgttgg ttgtagtaga tgcgggagtg tgggaccgtg ccgccggaag ggccttgcat
     3241 gatgtgcttg attctgacat gccgggactg ccccagtcgg aaccttcttt ccggattatg
     3301 tatacttcac cgaaggacta tgattctacg ctgaagttga tccgtaatat tgtgatagta
     3361 gatataaaag atatttatac caaaggtact ttcaagtatg cgaaagacgt ttatgcttct
     3421 ccacagatga tactgaccat tcaggctccg aacgaagaag tgtttgagaa gtttgtcgaa
     3481 gaaaacaagc agacgattat cgacttcttc actcgcgctg aaatgaaccg tcagattact
     3541 ttgctggagg aaaagcacaa caactttatc tcaaataagg tagatagtct gtttgactgc
     3601 gatatctgga taccttccga actgaataac tccaagacag gagaggactt cttttgggca
     3661 tctaccaata caggcagcgc ggatcgcaat ttcgtgatgt attcttatcc ttatactgac
     3721 aaggatacat tcaccaaaga atactttgtt cataagcgcg attctgtgat gaaagccaat
     3781 atccccggat ataaagaagg cgtatatatg tcgacagact cgttactgac cgatgttcgt
     3841 ccgatcaacg tgcacaatga ctacacgatg gaagctcgtg gattgtggcg catgaagggt
     3901 gacttcatgg gtggcccatt cgtttcccat actcgtctgg atcagaagaa ccaacgtatt
     3961 attacagcag aaatatttgt atattcaccc gataaaatga aacgcaatct ggttcgccag
     4021 atggaagcat ctctttatac gctgaaactt ccgcaagaag gtcagcagag tcagattcca
     4081 ctgggggtaa ccagagaagc ggaaccaact aataaataaa aacatggaag aaaacaaaat
     4141 aagaatcggc attacccaag gagatatcaa cggggtaggt tatgaagtga tcttgaagac
     4201 attctcagac cctaccatgc ttgagctatg tactccgatt atctacggtt cacctaaagt
     4261 agcggcttac catcgtaaag cactggatgt acaggctaat ttcagcattg tcaacacagc
     4321 ttccgaagcc ggatacaacc gtctgagtgt agtgaactgt acagatgacg aagtgaaagt
     4381 ggaattctcc aaacccgatc ccgaagcagg taaggctgca ttgggtgctt tggagcgtgc
     4441 catagaagag tatcgtgagg ggctgatcga cgtcattgtg acagctccga tcaacaaaca
     4501 taccattcag tcggaagagt tctctttccc cgggcataca gagtatattg aagaacgtct
     4561 gggcaatgga aacaagtcac tgatgatcct gatgaaaaac gattttcgtg tggctttagt
     4621 aacgacgcat attccggtaa gggagattgc tacaacaatc accaaggaac tgattcagga
     4681 aaagctgatg attttccatc gttgtctgaa acaggatttc ggtatcggtg cgccccgtat
     4741 tgcagtgctt tcactgaatc ctcatgcagg agacggcgga ctgctgggta tggaagaaca
     4801 ggaaatcatt atccctgcca tgaaagaaat ggaagagaaa gggatcatct gttacggtcc
     4861 ttatgctgcg gacggtttta tgggttcggg caattatact cactttgacg gaatccttgc
     4921 tatgtatcat gatcagggac tggctccgtt caaagccctg gctatggaag acggtgtgaa
     4981 ctataccgcc ggactgccgg ttgtacgtac ctctccggct catggaacag cctatgacat
     5041 cgccggtaaa ggactggcca gcgaagactc tttccgccag gctatttatg tagcgattga
     5101 tgtattccgc aaccgccagc gcgagaaagc ggcacgggta aacccgttgc ggaagcagta
     5161 ttacgagaaa cgggacgata gtgataaact aaaactggat acagtagacg aagattaagt
     5221 aataggtatt aagtaataag tattaagtat tagccatgcg gatggaagcg agatgataat
     5281 gatggtaata cttaatactt attacttaat acttattacc tattacttaa tattaagata
     5341 gatgaccaaa gcggagatac aacaagtgaa acagcgtttc ggtattattg gcaataccga
     5401 ggctttatca cgtgccatag atgttgccat tcaggtagcg cctaccgatt tgtctgtgct
     5461 gattaccgga gaaagtggtg tcggaaaaga aagttttcca cagatcattc atcaatatag
     5521 ccggagaaag catgggcagt atattgctgt caactgtggt gccataccgg aaggtacgat
     5581 cgattccgaa ctgttcggac acgagaaagg agcatttacc ggtgctattg gtgagcggaa
     5641 aggatatttt ggagaagctg acggtggaac catcttcctt gatgaagtgg gagagttgcc
     5701 gttgcctaca caggcgcgtc tgctccgtgt acttgaaagc ggtgaattta tcaaggtcgg
     5761 ttcatccaaa gtgcaaaaga cggatgtacg tattgtggca gctaccaacg tgaacctgac
     5821 acaagccatt gccgaaggac gctttcggga agatttgtat tatcggttga acacggtgcc
     5881 tattcagata ccacctttgc gtgagcgcgg agacgatgtg ctgttgctgt tccgtaagtt
     5941 tgccgcagac tttgccgaaa agtaccggat gccggctatc cagctgacgg aagatgccaa
     6001 gaagatattg cttgcttatc cgtggccggg aaacgtccgg cagttgaaga acatcacaga
     6061 gcagatttcg attatagaaa caaaccgtga gataacggct gcgattctgc agacctatct
     6121 tccggcacag aatacccaac gccttccggc actgttcggc acacgcgaga gcaagagctt
     6181 tgagagcgaa cgcgaaatac tatattctgt cttgttcgat atgcgccagg aagtggcgga
     6241 actgaagaag atggtgcaca atatgatggc cgaacgtgcg ggacaagtcg gacagatggg
     6301 acaggtagta gctactccgg tagtgacaac gacgcaccaa ccttccgtgc cggccataat
     6361 ccatgctgtg cagcaaccgt ctgtttgtcc caaagaagac gatgacgata ttcaggacac
     6421 ggaagagtat gtggaagaaa ccctttcgct cgatgaagtg gaaaaagaaa tgatacgtaa
     6481 agcgcttgag aggcatcatg gtaagcggaa aagtgcggca aaggatctga atatctccga
     6541 gcgtaccctt tacagaaaaa taaaagaata tgaattggat taagaaaata gcacgaccgc
     6601 tgatattggt tgttttaccg gcagtcatca tcgcctgtag tgtgtcctat aagtttaatg
     6661 gctcctctat caattacgat aaggtgaaga ctatttcgat tgctgatttc ccgattaagt
     6721 cggagtatgt gtatgctccg ctggctacca agttcaatga agacctgaaa gatatcttca
     6781 tcagacagac ccgtctgcaa ctgctgaaac cgaaccagaa tgcggatctg cagattgacg
     6841 gtgaaattac gggctacaac cagtataacc aggcagtgtc tgccgatggt tactcttcgg
     6901 aaacgaagct gaccatcacg gtcaatgtac gctttgtcaa caacacaaat cacgccgaag
     6961 acttcgaaca acaattctca gctttccgta cctatgattc cagccagctg ctgacagccg
     7021 tacaggatgg attaatagcg gaaatgagta aagagataac cgaccaaata tttaatgcaa
     7081 ctgtagcaaa ctggtaattt aatgacttct gttaacttgc aacaatggat tcagcatccc
     7141 gagacgctga atagggatac tttgtacgaa ctgcgcaatc ttcttgcgag gtatccgtat
     7201 tttcagtcac ttcgtctgct gtatctgaag aatctgtata ttctccatga tattagtttc
     7261 ggtggagaac tgcggaaagc agttctttac attgcagaca gacggcagtt gttccggttg
     7321 attgaaggtg accgctatga tgtgcaggca cgaaaaaagg gagtacctct cacggaggtg
     7381 ctgaaagacg aaccgtccgt agaccgcaca ttagcattga tcgacgcttt cttgtccaca
     7441 gtacccgaag aggtgactgc ccgcaccagc ttcgactatt cgatggatta cacctcttat
     7501 cttttggagg agactccggc cacggaacag ctggccgaag aaacgcccaa actcaaaggc
     7561 tacgaactga ttgacgactt tatagaaaag agcgagagcg actctcccct ctgcaagaaa
     7621 cctttaagag aagaaatgcc atcttcgcca acctcttcgg acgaacttac cgaagaagaa
     7681 acgatgaagg aagaagagga agatgacagc tgttttacgg aaactttggc aaaaatctat
     7741 gttaaacagc aacgatattc aaaagctctt gaaataatta aaaaattaag cttgaaatat
     7801 ccaaaaaaaa atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac
     7861 gctaattcaa aataactaaa aatgtactta ttattcatta tcttaatggt gattgcagcc
     7921 ttgctgatgt gcttcatcgt gctgattcag aattcaaaag gaggcggact tgcttctggt
     7981 ttttcttcat caaacgctat catgggcgtg cgcaagacta cagattttct ggaaaaagca
     8041 acttggggtc tggctatctt catggttgtg atgagcgttg ctactgctta cgttgttcct
     8101 tcttcttctg cagctaaaga tgtattgttg gaacaagcac agaaagaaca acaaaccaac
     8161 ccgtataata tgcctaccgg tactgctgct cctcagacag atgctactgc tcctgcagag
     8221 tctgcaccag caacggaagc tccggctact gaaactcctg ctcctgcagc agaataattc
     8281 agtgacagga tattcggttt aaacttattg agtgaacggg ctttttgacc cgttctcttc
     8341 attataggcg cgaattacgc gaattacaag agattctaat agaatcgtgt aatacgtgta
     8401 gttcgcgcct gtctttatta ttgggcccgg tctgctcttc ttcatacagg aatatccggt
     8461 cagatgtcct ttttcttata aaatgttctc cttttttagt aaaacaaatg ataattagtt
     8521 aactttgttg cccgttacga gattattaac tccttttaaa tattacaatg acagaacaat
     8581 tgaaacaaaa gctgaatgac tccgcagtgc tgcgttggag tgttctagca ttagtcgctt
     8641 ttaccatgtt gtgcggctac ttcctcacag acgttatgtc tcctctgaaa cccatgcttg
     8701 aaaaagaact tctctgggac agtttagatt acggtttttt caccagtgct tatggctggt
     8761 ttaatgtatt cctgctgatg ctcatctttg gtggtatcat tctggataag atgggagtac
     8821 gcttcaccgg aatgggtgcc tgtttattga tggtgttcgg ttgtggattg aaatattatg
     8881 ctattactac tactttcccg gaaggtgcga tgcttttcgg attcaagatg caagtcacat
     8941 tggctgcatt gggttatgct attttcggtg taggagtcga aattgcgggt atcaccgttt
     9001 cgaagattat cgtgaagtgg tttaaaggca aagagatggc tctcgctatg ggactggaaa
     9061 tggcgaccgc gcgtattgga acgactttgg ccatggtgct taccgttcct ttggcagact
     9121 tcttcgggtc tacggatgag agcggcgtat tccataccaa tattcccgct ccgattctgt
     9181 tctgtctcgt catgttgtgc gtaggtacca tcgcattctt catctatact ttctacgata
     9241 agaaactgga tgcttcactg gatgcggaag gactggaacc ggaagaacct ttccgcatga
     9301 aagacattgt ctatatcatt accaacaaag gattctggct gatcgcatta ctgtgcgtat
     9361 tgttctattc ggctgtattc cccttcatca agtatgcggc cgatttgatg gtacagaagt
     9421 acaatgttga tccgaaactt gcgggaacga ttcccggatt gctgccgatt ggcgcgatca
     9481 tcctgacacc gttgttcggt tcattgtatg accgtatcgg taagggagcc acgctgatgg
     9541 tgatcgggtc ggtgatgctg attttcgtac acacgatgtt cgctcttcct attctgaata
     9601 tatggtggtt tgcaacggtg atcatgatta ttctgggatt tgctttctca ttggttcctt
     9661 cggcaatgtg gccttcggtt ccgaagatta ttccggagaa acagttggga acggcttatg
     9721 cgttgatctt ttgggtacag aactggggat tgatgggcgt gcctttgctg atcggatggg
     9781 tgttgaactc ttattgcaaa ggtccggttg tagatggtgc acagacttat gattatacct
     9841 tgccgatggc tatttttgct atgttcggtg tacttgccct gattgttgcc ttgatgctga
     9901 aagtggaaaa caagaagaaa ggctacggac tggaagaagc aaatattcag aaataatcac
     9961 agtatatatt ctatctgaaa agatataaaa gagaaaagat atggctacga aagagaaaat
    10021 aaacctcctg gaggtgatcc cttgtcgtaa cgaacatatt aaagctgaac aggaagggga
    10081 gactattgtg ctctccttcc ctcgttttaa acgttcgtgg atgagtcgtt atttattgcc
    10141 gaaaggaatg tccaaagata ttcatgtgcg tctggaagaa cacggtacgg ctgtatggaa
    10201 cctgatagac gggcagcgga cggttcgtga gattatagaa aaactcgcag accactttca
    10261 atatgaagca ggctacgagt ctcgtgtatc tacctatctt tcccaattac agaaagacgg
    10321 atttattaaa tggataatta tccattaaaa aagattgccc acaggaggac agcacatcct
    10381 atcagtacgc ccataatgat gagcgttccc catacgaaat agctgttatc tttttctttt
    10441 ttcttttccg aatccttgat gatgcgttcc atctcttccg gagtcgtatc cggcagaaga
    10501 taagggtcgt tgtttcttct aagtcgccct aacttgtcat ttctccgttc acggcgtaag
    10561 cgggaggctt ctttgccgtc tttcagccga cgtatcatgt cgagcatatg tccttcgcca
    10621 cccatcgttt tgttttttta gaggttttat ttgctttctt ctctatctac tttcagtagt
    10681 ccaccggtca ccggatcaaa gtaaactttg atggtcgagt tcttgttgaa taataccgga
    10741 gcaaggtatt ctatgatacc gaactgagta acaggtattt ctccttcata caatttcttt
    10801 ttgccgtccg tcagcgtcac cattgcctgt cccggtacgt tataagcaat gccttccatc
    10861 tctttcttct ttttcccgtc ctcttgcgga atcttcaccg ttttcaggtc tttcagactg
    10921 atgtagaatg gagtgcctgc caaatcgttg ttggcaacta tacctagctt ctttgaaaag
    10981 cggaaagcta cctcattgtc gaattcctta tccggagtga ggcggacagt aaatgtcttt
    11041 tcttctttat tgcggactcc cgaaaacatc tcggtcatgg cttcttcctg aagattcagg
    11101 ttgtcgagca tgattttgag ctgtgcgccg tccgaaggca tattatctgc ttgtccgcgc
    11161 aataatgcgt ttttactttc gcggatatta tagatttcct ttgctaccaa ttcggccatc
    11221 ttggcggtgg aacttgccat cagaatttct tctgtgagaa agtcgcgggg attggctttt
    11281 cgttggggag caacggcatt gtttgctgca ttctttgcat tgttgctgct gtaggggacg
    11341 ttgattgatt tgataagacc ctcttcagtc agttccataa gaggagctac ggttttgtct
    11401 ttcagtttga cgaaataagt agcttcgctg tttggtacac ctacaggttt cactttgaca
    11461 ctgttcagtt cccagtattc ttcgggttcg gcagagacgt tggtcagtct caggtagcgg
    11521 tcggcgtatt tgctgaattc acccggctta tagttgactt tgtttgcttt tatttctatt
    11581 tctatctggg ttttggggag ggcgtacact actccgtagt cttttcctcg cgtcactcct
    11641 gtcagcactt cggtctgcgc ataggcggaa gttgccatta gtagtcctgt tgctatgata
    11701 aactttttca tattcggttc tttttagctg attttgaaaa acaaagttaa tgaagttatt
    11761 gaataaaccg taagttctta acttttattc gcttacaagt cgccatgccg tcggcagaca
    11821 ggtgacgata tcacttgcga ttaatccgat catgccctgt tttttctggg cgatgtctcc
    11881 ggccaatccg tgaatgtaag taccgatctt tgcggcgtct tcggcgggat agccttgcgc
    11941 aaggagtgca aggattactc ctgtcagtac atctccgctg cctcctgttg ccataccggg
    12001 attaccggcc tggttgaagt aacatttgcc ttcgggggtg ataatggcgg aataagctcc
    12061 cttcagaatg atatgtactt tggcagtgtg cgccagttcg caggctttca tcagtcgttc
    12121 gtatgagtcc tgacatttgc cgaccaggcg ttccagctct ttcgggtgag gggtgaggat
    12181 ggaacctttc ggcagatggg tgagcgtatg ccggtgattg gccagaatat tgagtgcgtc
    12241 ggcatccagt accgtcggag tctgacaatg ttccagttgt tctatcaggg cggcttccgt
    12301 ttcctcgctg cgaccgagtc ccggaccgat gccgacagct tggtaatcgt ccgtatcggt
    12361 aggtacggca aagcatgttt cgctgacatc tgtttctacc atggcttcgg gggcggacgt
    12421 ttgcaaaata tcgttgttgc ataacggcgc gtgtaccgtc agcagaccta ctcccgatcg
    12481 cagacaggca cgggcggcca gtaccgatgc acctgccatt ccttttgagc cggctatcag
    12541 cagggcatgt ccgaagtttc ctttatgggc gaattgttgg cgtggtttga tcagtgaacg
    12601 gatttcttcg atttccagca tttcgtagtt tgtttcagtc tcttcgattc cttcttcgct
    12661 cagctggatg tccaataact cccattcgcc aacaaattct gtattttcgg caaagaggaa
    12721 ggccagttta ggaagttgca ggctgaaagt gacgtccgca cggataatat tgctttttac
    12781 attgaatgta ttttcttctc ccatcagtcc ggaagggatg tcgatggaga ctaccatggc
    12841 gggagaggca ttgatatatt tcacaacggc agcgaatcct ccgctcaatg gtttgttgag
    12901 tccggaaccg aataatccgt cgatcacgag atgctccgat gtcagtgtgg gcggtacgaa
    12961 ctgggtgctg atttcatgga aagttacttc ttccatcatc tctaccagtt ctttgttggt
    13021 ctgacagtcg ggcgaaagtt cgcctttcgt gttgaagaga tatacttcga tcttgtatcc
    13081 tttttccgcc atcatgcggg cgatggcgag ggcgtctccg ccattattgc ccggtccggc
    13141 aaagatggtg acaggtgttt ccggattcca tctgttggtg atggctttag tcagcgcctg
    13201 tgcggcacgt tccattaaat ctatggatgc aatcggttca tgttcaatgg tataggcatc
    13261 taacttctta atgctgctgc ttggaaatat tttcattgcg atattctttt agttttcgac
    13321 gcacaaactt acacaaaaac tctgaattaa tcctttattc cggttggttt tcggcttttt
    13381 gggaaggaac ttcaggtatt aatacttgag ttgtcaggta ttaatagttg atgtgtcagt
    13441 tattaatagt tgagaagtca gatattaatg attgttatct catttacttt tactctctcc
    13501 ggagaacatt catggctgtt tgttaacctt cccatgcgtg tttctactac tgtatattcc
    13561 tctggttcac ctctttcacc cgcaatcgcc ttattcatca aaggttcagg aaaagggtgg
    13621 aagaggtgat tgtgataaat atgctatggg catattcttg attagctaat agcttattgt
    13681 tttttgctaa atctaatggg gagtttgctc atataataaa tactctattc actctgctaa
    13741 agaagaaaat cagtgtagtt ctcattctgc tatttgaatc agatatgcat tttccagtgc
    13801 aaggtaatct tgtttgtact gtgcggttaa atctctgaca aaacagtact gaattaacgg
    13861 atgagcattc attcttgtat tgaggagtgg tagaaagttc ttggtaatat agaaagtatc
    13921 aataactttg ccattatctt ctttgattgt tatacggtaa tactcactca atttgtattc
    13981 acctttgatg ggaatggcat tttcttcatc cagcactata tgttcttttt caaagttgcc
    14041 tgttttcatg ttattatctg aataatacaa atctactgtt cctttgctgt cttccgcatt
    14101 cataaaagta aatacatatt tattaatcgg atatgaattg cccactttgt tcattaactc
    14161 agtgtgttct tcagatgtaa gctcgtctcc cttcacaatg acttttgctg taaacgcctt
    14221 atgagtaaga gtacgatatt ttacaacgac agacagtata tacatattat tcgaactgtc
    14281 ttctatcttg atggatgcgc gtcctatttc ctttgccttc aatgttaaac ttccgttgtg
    14341 gtagtttact tgtaccactt tctcattctc attggtcact ttgtaagttc cgtctccacc
    14401 cttgatgaag agtggtgtcg tttctttgct gaacggagtc agtgtgtaag aacggctctc
    14461 gttgtcgaac ttaatttgag gatcttcata ttccagagtg attggagaaa agttgtcatc
    14521 attgtcatta cagctcacga ggcaaataat acaaagaaat aacgaaagta ttcctgttag
    14581 ttttttggta gtcatgctaa ttaaagtttt aaatgtgcga tattagttta gttctcgtct
    14641 gcaaacttat gaaaaagaat tgaactgttt ctttatttgt gctatttttt agcagagatc
    14701 ggcataaatg attagaatgt aactaataat agcagctaat gctttgatta tttgcttttt
    14761 tcgagaaaaa tgatatcttt gtagtgcagt aatgtgcttt acgttattct cctgtgctca
    14821 caatgtttag attataaata taaattgttt aatcttctaa agtttgcatg atggaaaaga
    14881 aaagaattgg ctcaaatgcc gggaaagtat ggcgcatctt aaatgaaaag ggcgaacagt
    14941 ctatgttcac tttgtgccat gagttaggtt tgacgttcga ggatgtagcg attgctatcg
    15001 gttggctggc aagggaaaac aaaatcctgc ttagaaaaaa agaaggaatg ctctatgcca
    15061 gtattgagaa tgttgaattt acctttggat aaatggggac tgacccacat ttaaggagaa
    15121 tatccacttg attatttaca ctgttgaaaa cataataagg tgggtaactg agacttcttg
    15181 cacgccatcc tgtatttttc tattccataa gaatcttctt ttttgaggca tttaatctac
    15241 ttttctgtac ctttgcaccc cataaactac taaacacata attcatgagt tcattgaaag
    15301 ggcacccgaa aggcctttac ctaattttcg caacgagcac ggcagaacgt ttcagttact
    15361 acggtatgcg tgctatcttt atcctctttc tgacgcaggc attgcttttt gataaagaag
    15421 cggcggcctc tatctacggt agctacaccg gactggtcta tctgactccg ttgatcggcg
    15481 gatacattgc cgataaatat tggggcatcc gtcgttcggt attttgggga gcggtgatga
    15541 tggcagtcgg tcagttcctg atgtttatga gtgcctcttc actgaacaat acagaccttg
    15601 cccactggct gatgtatggc gggctcggat tcatgatttt aggtaacggt tgctttaagc
    15661 ctaccgtttc ttcgctcgtc gggcaattat atgaacccgg ggacaaacgg ttggatgctg
    15721 catacaccat tttctatatg ggtgttaatg taggttcttt cgctgctcct ttgatttgcg
    15781 gtttcttggg agacacaggg aatccgcagg actttaaatg gggattcctc gcatccggaa
    15841 tcatgacgct gttcactgtt gtcctctttg aaactcagaa gaataaatac cttttctctc
    15901 cttccggtga accgattggt atcgtccccg acgccagacg tgaaaaaaag gaggataaag
    15961 ccgaacatat ttcacatccg aagatggaca aacgtaccaa agtacgtaat atcatcatca
    16021 ttactgccct tacagttgcc ttaatagctt tttttagcta tgcctttagc gatgactgga
    16081 ttagtgtggg tatctttacg gcttgtattg tctttccagt gctcattctg ctggatggtt
    16141 cattgaccaa agtagaacgt agccgtattt tcgtaatcta tatcgtagct ttcttcgtca
    16201 ttttcttctg
//
