LOCUS       c00157_gnlPro..        13073 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OFLLDNEI_157.
ACCESSION   c00157_gnlPro..
VERSION     c00157_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:16:50
            Original ID  :: gnl|Prokka|OFLLDNEI_157
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 36418
            Orig. end    :: 49491
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13073
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[46418:49489]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13071
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13073
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="GR_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13073
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_fatty_acids"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2434..5166)
                     /locus_tag="ctg157_28"
                     /transl_table=11
                     /translation="VCAFFPECARAGDSVAGEDAAGSSESTDYPGRKKETWKLIKKEAW
                     AQDVFNKLKERTEVYTRRTESQPDWLLSRLAMYWKSHATEVYVKGEVFDHAGGAKAPAP
                     TVRYTGTRGTAATHGRPKLEDVVPYDDSAEGNVTFCNNALKGRPLESVHPSKTGRNIES
                     LNCEILGIARDAAFLYWMTGEEKYARLAAGVFDTYMTGIYYRNVPVDLNHGHQQTLVGL
                     TSFEVIHEDALHIVVPLYDFLYHYLQSNYPDKMMIYAGALKKWADNIIANGVPHNNWDL
                     LQARYIMNVGLVLEDNKEYADGKGREYYIDYVMNRSSIRQWSLTKLADYGFDSETGIWA
                     ECPGYSSVVINDYANFTHQFDHNLQYDLVKAMPVLAKAVATTPQYLFPNRMICGFGDTH
                     PSYLSTNFFIRMIQNAQANGKKEQERYFTALLKCLNPEEGSEKSGKKNVRASVNSFFED
                     KPLVLDPKVEAGKIEDYVSPLFYAPNVSWLVQRNGMHPRNSLMISLNASEGNHMHANGI
                     SMELYGKGYVLGPDAGIGLFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVMKSNHSFDL
                     LSCFPASAEPGKGFTSVTYSQVAFREPESRADQTRLMGIVTTGPETGYYVDVFRSRKER
                     GGDKMHDYFYHNLGQTMTLTAADGTDLNLQPTEELAFAGDHLYAYSYLYDKKVATTGQD
                     VKVTFTIDMKDKGGDDISMNLWMKGEPEREVFTALSPMTEGLSRTPHMPYNIKEQPTLT
                     FVARQHGEAWNRPFVAVYEPSTQKEPSAIQSVSYFDAEEPGLKDFAGICVESKNGRTDH
                     IFSLTDSSQTATYQGMKVKADYAVISNEYAGNRTLFIGNGTQLIASGISIQTSEAANVL
                     LEKKQGKWYILSSAPCKMVIDGKAVQSGITTELTLLAVQ"
     CDS             complement(5830..6642)
                     /locus_tag="ctg157_29"
                     /transl_table=11
                     /translation="LFNRFFEAIDGQRIFGADVDQSFGGTDGVTADAHRFYNRVRVAFH
                     DGAVHEGAGVAFVGVADNVLYVRCLLTGKFPFQAGGETTTATPPQSGAFDDVDDVGRLF
                     VEKTVGQCEVSFTGDVFFYIFGVDESAVAQGDAELFPVEVHVFGVADGLLGLRVYVEQP
                     SDSSSSDDVFADDFLRIFGSDLGIERIVRNDLYDGALFAEAEAAYCDDVYFVGNPVSFD
                     GFLKIFSDALTGRGFTTGTSANKNLEVCCSGRQPATFFGNLFITFFAQ"
     CDS             complement(7081..7542)
                     /locus_tag="ctg157_30"
                     /transl_table=11
                     /translation="VATDTKFRINGIGQQGLALFGAAGLVSDVFQIFVTEVVEGRQYRI
                     RGRLSQSAECRILYHPSEGGKRVQVFFRAPSFRYLVQQFQQALVADTAWGTFTAGFFDG
                     KVEIETGDGYHTVIFVHHDHASRSHHGTGCQQVVEVDGSIQMFLRQTAP"
     CDS             complement(7674..9146)
                     /locus_tag="ctg157_31"
                     /transl_table=11
                     /translation="VCDAYFQFKSVQVDGGAPDTAQSAYLFKVDILQRLSGVDFINGAQ
                     GGFHDTTRRTEDDTGAGRFSHRVVERAVQHEGKADVGSLYQACQFAGGDGVIDVGDTVY
                     FELVAVTFIFLGQTGHDGDNYQLFAGDSHFLCPVRLGDGAEHLLWRTGGRRDIQHIREV
                     VLEEVYPSRAAGSQDRKPDGFISVQIACQSVQDFGTFFHDGEVGGKVGIEYIVETQFAE
                     GVNHFSGYQCAGRQAEFFSQGGTYGGGSLDNYDLIGVGQIVQKAVGVIPFSQCAYRTYG
                     YALTAVGTFAILHHSVEGRGYCCVESAADGSQCADCLYIVADTFASAAEDALVHVAHNG
                     GGHFPFAGRKFAAVERHFTDVEAQCQCLEFTVAAFGTGEAVVGMIGQDQFGYHFPGVHH
                     AQGTGFHYHPFRATGSAGGSQIAASCHFDYTDAAGSGIVLDAGSFQVDVTQRRYVDADF
                     AGGFEDGASFGYGDKVTVYLEGNLFFFHSSRF"
     CDS             complement(9168..9431)
                     /locus_tag="ctg157_32"
                     /transl_table=11
                     /translation="MRVQEHFRFLTQRFAEVFFIQFLNIGVVVRFAQRFVGIFPVKGVG
                     TGVENVRVAVMQGLPATSDAAAGACHDFDDMIFIMSVSYIFQ"
     CDS             9474..9950
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg157_33"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 2.3e-54,
                     bitscore: 174.4, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVVEQVKTICDKHGNNAGELINILHEAQHLHGYLPEE
                     MQRIIASKLRIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKYSLDCLRCVGACGLAPVVMIGEKVYGRLQPVDVKKIIEELE"
     CDS             complement(10001..11008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: ACP_syn_III_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_34"
                     /sec_met_domain="Thiolase_N (E-value: 1.6e-11, bitscore:
                     35.2, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 6.2e-33, bitscore:
                     103.9, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 4.6e-34, bitscore:
                     107.8, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKINAVITGVGGYVPDYVLTNDEISKMVDTTDEWIMGRIGIKER
                     HILNEEGLGTSYMARKAAKQLMQRTKSRPDDIDLVIVATTTSDYRFPSTASILCERLGL
                     KNAFAFDMQAVCSGFLYAMETGANFIRSGKYKKIIIVGADKMSSVIDYTDRATCPIFGD
                     GAAAFMLEPTTEEVGIMDSVLRTDGKGLPFLHIKAGGSVCPPSYYSLDHHLHYIYQEGR
                     TVFKYAVANMSDSCEAIIARNHLTKEEVDWVIPHQANQRIITAVAQRLEVPSEKVMVNI
                     ERYGNTSAGTLPLCIWDFEKKLKKGDNLIFTAFGAGFAWGAVYVKWGYDPKEDA"
     CDS             11141..11362
                     /locus_tag="ctg157_35"
                     /transl_table=11
                     /translation="LAKEREVLTKFQIQRRERDSNPRYTFGVYTLSKTAAIDHSATSPK
                     LPYQKCFSLKAVQRYEDILNLQEFSLKI"
     CDS             11512..13071
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_acetate1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_36"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1027.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLIEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIA"
ORIGIN
        1 ctgatcacga ctggattcct gacactgacc attaggataa atataatatt gaagctgttc
       61 gtcataacca taatcctgaa tatcattctt ccgttgtaac aatttataat caatcatagt
      121 aggagaaaca tgaatgggtt gatcgctgga aatagccggt cctgaaggat atggcaaatc
      181 atctttacga tgtttcattc ccagtaaata gcgataagca cggtcataca ttatctcatt
      241 atcaagatag atagccattg ccatcatact gcgtgctgca aacaatcctt gattaccgaa
      301 acgcgctgca tcaaaattat agatattcca ataaaaagtt actccatttt ttgtatcatc
      361 cagataatta gcatatttag cagaataatt ttccgtatta ctataccccg gataaaccag
      421 catatctttg aaacgttgct gatcttgccg tgtccatcca gaataatctc tcatcatttc
      481 agccgcatca atcaacaaat aaattttccc attatccaac ggtcctgtac cacggctact
      541 agtattagta taataagaat ttgcattcaa atattctaca gccttacgtg cataggcttc
      601 ttctcctgtc aagtgccaaa gaagagctaa atcatgagca cgacgcccat ccaccccgat
      661 tgtagcatta aatcgccctt cctttatttg ctctccacga ttcaccacag gtgcatcaag
      721 tgatgaataa gaagactcct tcaatttcaa aaaggtagaa taataaggtt cttgtctggc
      781 ttctaccatt gctttcatac gatcgaggtc accttgcgta taagtaatac ccggatgaac
      841 aaaacgacgt tgtgactgag ctacatcact tgtaaaaaca atattttcca catgaggtcc
      901 tacatatatg cgtgccatat ctgaagtctt ataccaccga ggtttgtccg gcatattatc
      961 atcaatcaat tttccattta ttttcaaatt ttcaaaacgt atgttcttta ccttacgttt
     1021 ttcatcatat ccttcaataa tagaaagttc cgcattctct ccggtatagg atatattctt
     1081 aaacaatacg ttctcaattc ctcttccggg agcagtacag tatttttcat tataaaagat
     1141 acgtaaattg acaagttgcc cctgacggaa attctcaaca cggatgtcct caaaatgaac
     1201 attgcgtatt aaattgttat cacctgcatt aatagccata catccttgat aatcgacttg
     1261 tttctctcta tgatccaata tatcaatatt aatataattc agatcttcca aaacttcggg
     1321 agctttagaa ttaccatgaa ttccaataaa aataggatgg gctacatctg cccaaagagt
     1381 ggaattctgc attgttatat tccgacaacc tccttcaaat cccaaacgag tgccataaac
     1441 agttgtacaa tcatctgagt tacggcagaa gacaccatca aataatacgt tattgctcgc
     1501 aaaaacattc atgccatctc cccacccata ataactaata cttttgacat tacggatagt
     1561 aacattttcc gaccctcctg tcgcacattg agtagcaaca attccttcta catagacatc
     1621 tcgggaattc gcaatacgaa tacctccttt tatagaatga tcgataattc ctcttcctag
     1681 caattttaca tcatgtacgt tttcgattag gacacgcccc attaaaacag ctcctcctgc
     1741 cagatacaca gtcttaccgg atggcactct caattcccca tttttaactg tatgtattcc
     1801 aggaccaaag taaattactt ccggattatc tttgtccgga atcgttcttt ccggagatcc
     1861 tgtaaataag tgaaaattat gaaaaatatc cccatttact tctactgaca aatttcgagg
     1921 atgctctaat gtaaaagtta ctgtattacc atcgatctga aatgggatat catacgagag
     1981 aggacggact tttgccgtct gtacttctcc caaattatag gttacggcta cttccacttt
     2041 tcctgtaaaa tcaaaaattg ccatcgaagc attttctaca taatgtcgtg tatctcttac
     2101 ctcatccacc ttaatcagat aagaagataa ggtatgccag actccatctt gcaaacggac
     2161 cttaaccgta aaatcactat ttaaagcaac tcctgcggga gccttccaag ttgcaagtgt
     2221 gtctttagca aagatacaag ttgcaccacc taataatgca gctaataata agaaccaata
     2281 tttcttcatg atattatcga ataaaattct tttatagtat tacgaacaat aaagacgatt
     2341 cacctattct ctatcaaaga tatttatgaa aactcgcaaa acaacaatcg ttcaattaaa
     2401 acaatgatat gtttattcat ctaacaatga ttcttattgt acagccaata acgtcaattc
     2461 ggtggttatt ccagattgca ccgcttttcc gtcaatcacc atcttacagg gggcagaaga
     2521 aagaatatac cattttccct gcttcttttc gagcagcaca ttagcagcct ccgaagtctg
     2581 gatactgata ccggatgcaa tcagttgcgt tccgttccct ataaacagcg tccggtttcc
     2641 cgcatattcg ttactgatta cggcatagtc cgctttcact ttcattccct gataggttgc
     2701 ggtctgcgac gaatccgtca aagagaaaat atggtcagta cgcccgtttt tactttccac
     2761 acagataccg gcaaagtctt tcaagccggg ctcttccgca tcaaagtaag agactgactg
     2821 aatagccgaa ggctctttct gcgtacttgg ttcataaaca gcaacaaaag gacgattcca
     2881 tgcttctcca tgctgccggg caacgaaggt gagcgtaggc tgttccttta tattataagg
     2941 catatgggga gtccggctca atccttcggt catcggtgac agtgcggtga acacttcccg
     3001 ttccggttct cctttcatcc agagattcat ggaaatatca tctccgcctt tatccttcat
     3061 atcgatggta aaagtcactt tcacatcctg accggtggta gccactttct tatcatataa
     3121 gtaggaataa gcataaagat ggtcacctgc aaaagcaagt tcttcggtag gctgcaaatt
     3181 caagtccgtg ccatcggcag ccgttagtgt cattgtctga cctagattat ggtagaaata
     3241 atcgtgcatt ttatcgcctc cccgttcttt ccggctgcgg aatacatcca cataataccc
     3301 tgtctccgga ccggtagtaa caatgcccat cagtcgagtc tgatccgccc tgctctccgg
     3361 ctcacggaaa gctacctgac tataggtgac ggaagtaaat cctttacccg gttccgccga
     3421 agccggaaaa caggaaagca aatcgaaaga atgattactt ttcatcaccg gataactgga
     3481 aatgccatct acacaaaccg tattatgact ggggaattga gagtaatatt ccgcatagtc
     3541 cagaccgcta tacagaaaaa gtccgatacc cgcatccggt cccagcacat atccttttcc
     3601 ataaagctcc atcgaaatac cattcgcgtg catatgattg ccttcactag cattgagaga
     3661 aatcatcaga ctgttgcgcg gatgcatccc gttgcgctgt accagccacg atacgttggg
     3721 ggcatagaac agaggagata cataatcctc gattttcccc gcctccacct tcgggtccaa
     3781 cactaacggc ttgtcctcaa agaaggagtt gacagaggcc cgtacattct tcttgccact
     3841 tttttcgcta ccttcctccg gattcagaca tttcagcaaa gcggtgaagt aacgttcctg
     3901 ctctttcttt ccgtttgcct gcgcattctg tatcatccgg ataaagaagt tcgtacttaa
     3961 gtaacttgga tgcgtatctc cgaaaccaca gatcatccgg ttcggaaaaa gatactgcgg
     4021 agtagtcgct actgcttttg ccagcacagg cattgccttt accaagtcat attgcagatt
     4081 gtggtcaaac tgatgggtga agttcgcgta gtcattgatg actacactgc tgtatcccgg
     4141 acattccgcc catatacccg tttcggagtc aaagccgtaa tcggccagct tggtcagact
     4201 ccactggcgg atgctcgaac ggttcataac gtagtcaata tagtattcgc gtcctttccc
     4261 gtccgcatat tctttattat cttccagcac cagtcccacg ttcatgatat atcgtgcctg
     4321 caataaatcc cagttattat gggggactcc gttggcgatg atattatccg cccatttctt
     4381 caatgcgccg gcataaatca tcatcttatc cggatagttg gattgcagat aatgatagag
     4441 gaagtcatac aaagggacaa cgatatgcaa agcatcctca tggatcactt caaaagaagt
     4501 cagccccacc agtgtctgct gatgcccgtg attcaggtca acaggaacat ttctgtaata
     4561 aattcccgtc atataagtat cgaaaacgcc ggcagccagt cgggcatact tttcctctcc
     4621 cgtcatccaa tagaggaaag cggcgtcacg ggcaattccc agaatctcac agttcagact
     4681 ttcaatattg cgtccggtct tggacggatg cacactctcc agcggacgac ctttcagggc
     4741 attgttgcag aaagtcacgt ttccttccgc actatcgtca taaggtacta catcttccag
     4801 cttaggtcga ccgtgcgtag cggccgtccc tcgtgttccg gtatagcgaa ccgtcggagc
     4861 aggtgccttc gcgcctccgg catggtcgaa cacctcacct ttcacgtaca cttccgttgc
     4921 atgcgacttc cagtacatgg ccaaacggga taataaccag tccggctgac tttccgtacg
     4981 tcgcgtatat acttccgtcc gttctttcag cttgttaaag acatcttgtg cccatgcttc
     5041 cttcttgatc aacttccatg tttctttttt ccttccgggg tagtcagtac tctcggatga
     5101 tcctgcggca tcttctccgg caacggaatc tcctgcccgt gcgcattcag gaaaaaaagc
     5161 acacacaatc ctaacaaaat tcgtctcata cttccatttc ttatttacgt ttgctacgta
     5221 tttaatacga aaataaggaa taatttacct aactggtatc agaaaacccg tttttatttt
     5281 caccggtacg gactgccttc atactccgga cattcaagta tactcaaaaa gatagcctgc
     5341 aagcatacca cttacaggct atcacaatcc ccttttttcc ctttgtatca gggaggcaac
     5401 ttacgtttcc ccgtccccgc cggaactctt gctgtacatc cttgccatca agctatataa
     5461 aactcataca aggagcattt tcccattcag atacagtacc ggcaggtccc cataagtcac
     5521 tccacaatgt tcttgcgaat ctccccaact attgttggat tcatatgggt attcgccctt
     5581 tttcgatgcg aagataattt ttttatgcta ctattatagt taacaccgtc tattaaaagt
     5641 gttaaaaata aagatttcat accatacttc cgcaagccga caccaaagaa gaatatttat
     5701 tttctctaaa caaagcgcta attccgaaca aagaattata tttgcagaaa tctaacaatt
     5761 ctgatactta tgaaaatact atctatccat gatttgcaaa taatcaggaa gagagcggag
     5821 caccatcttt cattgcgcga agaaagtaat gaaaaggttt ccgaaaaatg ttgcgggctg
     5881 gcgtccggaa caacacacct ccagattctt atttgcggag gtaccggttg taaagcctct
     5941 tccagtcagg gcatcactga aaatcttcaa aaagccatcg aaagaaacgg gattaccgac
     6001 aaagtagacg tcatcacagt aggctgcttc ggcttctgcg aaaagggccc catcgtaaag
     6061 atcattcctg acaatacgtt ctatacccaa gtcactcccg aagatgcgga ggaaatcatc
     6121 agcgaacaca tcatcggagg acgaagaatc ggacggctgc tctacataga cccgaagacc
     6181 gagcaaaccg tcagcgactc caaacacatg gacttctacc ggaaacaact ccgcatcgcc
     6241 ttgcgcaact gcggattcat cgactccgaa aatatagaag aatacatcgc ccgtgaagga
     6301 tacttcgcac tggccgactg tcttctcaac aaacagcctg ccgacgtcat cgacatcatc
     6361 aaacgctccg gactgcgggg gcgtggcggt ggtggtttcc ccaccggctt gaaatgggaa
     6421 tttgccagta agcaggcatc ggacgtaaag tacgttgtct gcaacgccga cgaaggcgac
     6481 cccggcgcct tcatggaccg ctccatcatg gaaggcgacc cgcactctat tgtagaagcg
     6541 atgtgcatct gcggttactc catcggttcc tccaaaggac tggtctacat ccgcgccgaa
     6601 tatccgctgg ccatcaatcg cctcaaaaaa gcgattgaac aagcccgtgc atacggatta
     6661 ctgggagacc acatcctggg gacagatttc agcttcgaca tagagatccg ctacggagca
     6721 ggcgcgttcg tctgcggcga ggaaaccgcc ctcatccact cgatggaagg aaaacgggga
     6781 gagccgaccc tgaaacctcc tttccccgcc gaatccggtt atctgggcaa accgaccaat
     6841 gtgaacaatg tggaaaccct cgccaatatt cccattatcc tgaccaaagg cgccgaatgg
     6901 ttcgcctcca tcggaacgga acgctccaaa ggaaccaaag tcttcgctct tgccggaaag
     6961 atcaacaatg tcggactgat cgaagtacca atgggaacta ccctgcggga agtaatctac
     7021 gaaatcggag gaggcatcaa gggaggaaag aaattcaaag ccgtacagac aggcggtccg
     7081 tcagggggct gtctgacgga gaaacatctg gatactccca tcgacttcga caacctgctg
     7141 gcagccggtt ccatgatggg atcgggaggc atgatcgtga tggacgaaga tgactgtatg
     7201 gtatccgtcg cccgtttcta tctcgacttt accgtcgaag aatcctgcgg taaatgtacc
     7261 ccatgccgta tcggcaacaa gcgcctgctg gaactgctga acaagataac ggaaggacgg
     7321 ggcacggaaa aagacctgga cacgcttgcc accctcggac gggtgataaa ggatacggca
     7381 ctctgcggac tgggacagac gtccccgaat ccggtactgt ctaccctcga caacttccgt
     7441 gacgaatatc tggaacacgt cagagacaag acctgccgcg ccaaacaatg caagtccctg
     7501 ctgacctata ccattaatcc ggaactttgt atcggttgcc acctgtgtgc caagaattgt
     7561 ccggcggatg ccatcagcgg cttggtacgc aaacctcatg tcatcagccc cgagaaatgt
     7621 atcaagtgcg gcatgtgcat ggcacgttgt aaattcaaag ctattcttgt ctgctaaaat
     7681 ctactgctat ggaagaaaaa caaattaccc tccagataga cggtcacttt atcaccgtac
     7741 ccgaaggaag caccatcctc gaagccgcct gcaaaatcgg catcaacata cctacgctgt
     7801 gtcacatcga cctgaaagga acctgcatca agaacaatcc cgcttcctgc cgcatctgtg
     7861 tagtcgaagt ggcaggacgc cgcaatctgg ctcccgcctg cgctacccgt tgcacggaag
     7921 ggatggtagt gaaaaccagt accctgcgcg tgatgaacgc ccggaaagtg gtagccgaac
     7981 tgatcctgtc cgatcatccc aacgactgcc tcacctgtcc caaatgcggc aactgtgaac
     8041 tccagacact ggcactgcgc ttcaacatcc gtgaaatgcc gttcaacggc ggcgaacttt
     8101 ctccccgcaa acgggaagtg acctcctcca ttgtgcgcaa catggacaag tgcatcttct
     8161 gccgccgatg cgaaagtgtc tgcaacgatg tacagacagt cggcgcactg ggagccatcc
     8221 gccgcggatt caacacaaca atagcccctg ccttcgacag aatgatgaag gatagcgaat
     8281 gtacctactg cggtcaatgc gtagccgtat gtccggtagg cgcactgact gaacgggatt
     8341 acaccaaccg ccttctggac gatttggccg accccgataa gatcgtaatt gtccagactg
     8401 cccccgccgt acgtgccgcc ctgggagaag aattcggctt gcctcccggc acactggtaa
     8461 ccggaaaaat ggtttacgcc ctccgcgaac tgggtttcga ctatgtattc gataccgact
     8521 ttgccgccga cctcaccatc atggaagaag gttccgaaat cctgaaccga ctgacacgct
     8581 atctggacgg agataaatcc gtccggcttc cgatcctgac ttcctgctgc ccggcttggg
     8641 taaacttctt cgagcaccac ttcccggata tgctggatat cccttctacc gcccgttctc
     8701 cacaacagat gttcggctcc atcgccaagt cttactgggc agagaaaatg ggaatccccc
     8761 gcgaaaagct ggtagttgtc tccatcatgc cctgtctggc caagaaatat gaatgtgacc
     8821 gcgacgagtt caaagtaaac ggtgtccccg acgtcgatta ctccatctcc acccgcgaac
     8881 tggcacgcct gataaagcga gccaacatcg gctttaccct cgtgctggac agcccgttcg
     8941 acaaccctat gggagaatcg accggcgccg gtgtcatctt cggtacgacg ggtggtgtca
     9001 tggaagccgc cctgcgctcc gtttatgaaa tctacaccgg acagccgctg aagaatgtca
     9061 actttgaaca ggtacgcgga ctgagcggtg tccggcgcgc caccatcaac ctgaacggat
     9121 ttgaactgaa agtaggcatc gcacacggac taggcaacgc aaggcactta ctggaagata
     9181 tacgaaacgg acataatgaa tatcatgtca tcgaaatcat ggcatgcccc ggcggctgca
     9241 tcggaggtgg cgggcaaccc ttgcatcacg gcaactcgga cgttctctac gcccgtgcca
     9301 acgcccttta ccgggaagat gccaacaaac ctctgcgcaa atctcacgac aacccctata
     9361 ttcagaaact gtatgaagaa tacctcggca aaccgctggg tgagaaatcg gaaatgctct
     9421 tgcacacgca ttatttcaac aaatcgattg attaacttta aacaagtact attatgtcag
     9481 atatcaaact agcctgcgat gtggtggaac aagtcaagac gatttgcgac aagcacggga
     9541 acaatgcggg cgaattaatc aatattttgc atgaagcgca acatctgcac ggctatctgc
     9601 ccgaagagat gcaacggatc atagcctcca aactcagaat ccccgtgtcg aaagtctacg
     9661 gagttgtgac attctacacc ttctttacga tgactcccaa aggaaagcat ccgatttccg
     9721 tctgcatggg cacggcgtgc tacgtacgtg gttcggagaa gttgctggaa gagttcaagc
     9781 gggtactcgg catcgaagtc ggagaaacca cccccgacgg aaagtattcg ctggattgcc
     9841 tgcgctgcgt aggcgcctgc ggactggctc cggtagtgat gatcggcgaa aaggtgtacg
     9901 gacgactgca accggtggat gtaaagaaga ttatcgagga actggaataa gtctcccccg
     9961 cccttcaaaa gaggatgtga cgtatcgggt atccgatatg tcacgcatct tctttggggt
    10021 catatcccca cttcacataa accgctcccc aggcaaatcc cgcaccgaat gcggtaaata
    10081 tcagattatc gcctttcttc agttttttct caaaatccca gatgcagagc ggaagcgtgc
    10141 cggcactggt gttgccataa cgttcgatgt tgaccatcac tttctcggac ggtacttcga
    10201 gtcgttgcgc cacagcggta atgatacgct ggttagcctg atgaggaatc acccagtcaa
    10261 cctcttcctt agtcagatgg tttctggcga taatagcttc acaggaatcc gacatattcg
    10321 ctacggcata cttgaacacc gtgcggcctt cctgataaat ataatgcaga tgatgatcca
    10381 atgaataata ggaaggagga catacggaac ctcccgcttt tatatgcaga aaaggcagcc
    10441 ctttaccatc cgttctcaac accgaatcca tgatgccgac ctcttccgta gtcggttcca
    10501 gcataaaagc ggccgcaccg tcgccaaaga tagggcaagt ggcacggtcc gtataatcga
    10561 ttacggatga catcttatca gcacctacaa taataatctt tttatatttc cccgaacgga
    10621 taaaattcgc tcccgtttcc atcgcataca ggaaaccgct gcaaaccgcc tgcatatcga
    10681 aagcgaaagc attcttcagc cccagccttt cgcacaagat agatgccgtt gaaggaaaac
    10741 gatagtccga agtggtagtg gcgacaatga ccagatcgat atcatcggga cgactctttg
    10801 tgcgttgcat caactgcttg gcggccttac gggccatata cgaagttcca agcccctctt
    10861 cattcaagat atgtcgttct tttatgccga tacgccccat gatccattcg tcggtggtat
    10921 ccaccatttt agaaatttca tcattagtca gcacataatc gggcacatat cccccgaccc
    10981 cagtaattac cgcatttatt ttatccatca agtctatttt cagaattaca aaaatgtgat
    11041 atctcaaaaa aaatatcggg cgcaaatata cagaaaagag aatgatatac aagagaagag
    11101 tactagaaat accagacact ttgacctatg aaaagaactt ttggctaaag aacgagaagt
    11161 tttgactaaa tttcagattc agcggagaga gcgggattcg aacccgcgat acacttttgg
    11221 cgtatacacg ctttccaaga ccgccgcaat cgaccactct gccacctctc caaaacttcc
    11281 ttatcagaag tgcttttcgt taaaagcggt gcaaaggtac gaagatattt taaacttgca
    11341 agagttttca ctaaaaattt aatctaatct tttcctaagg atagcaatta ataggtattt
    11401 tatgttgaaa agcataaaat agagcatatt tatgctgatt atatgaaaaa tgattgtaac
    11461 tttgtgcgct ctaaagaata ggataactac aacctctaat tttatcattt tatggaatta
    11521 aacaagatct ttaaagacgg tctttggagc agcgaaatca acgtcagaga tttcgtaagt
    11581 cataacatca ctccgtatta cggagatgct tcattcctcg aaggacctac agaacgtacc
    11641 aaagccgtat ggaaccgctg cctcgaagcg ttggcagaag aaagagaaaa caacggtgtc
    11701 cgctcattag ataatgttac cgtatcaacc atcacttccc acaaggccgg atatatcgac
    11761 aaggaaaacg aactgatcgt cggcctgcag acagacgaac ttctgaaacg tgccatcaag
    11821 cctttcggag gtatcaacgt agtcagcaaa gcctgtcacg aaaacggcgt ggaagtggac
    11881 gaccgcgtaa aagatatttt cactcactac cgcaagacgc acaacgacgg agtattcgac
    11941 gtatatacgg aagaaatccg ttccttccgt tcgctgggat tccttaccgg acttcccgac
    12001 aactatgcac gcggacgtat catcggtgac taccgccgta tggctcttta cggcatcgac
    12061 cgtctgatcg aagcaaagaa ggaagatttg cacaacctca ccggtccgat gacagatgcc
    12121 cgtatccgtc tgcgcgaaga agtggcagaa cagatcaagg cactgaaaga catgaaagtg
    12181 atgggcgaat actacggtct cgacctgagc cgtcccgctt acacggcaca agaagccgta
    12241 cagtgggtat atatggctta ccttgccgcc gtcaaagaac aagacggtgc cgccatgtca
    12301 ctgggtaacg tttcttcttt cctcgatatc tatctggaat atgaactgag caaaggaacc
    12361 atcaccgaat cgttcgcgca agagctgatc gaccagtttg tcatcaaact gcgtatggtc
    12421 cgccacctgc gtatgcaatc atacaacgac atctttgcag gcgacccgac ctgggtaacc
    12481 gaatctctgg gcggacgcct caacgacgga cgtaccaaag tgacaaagac ctccttccgt
    12541 ttcctgcaga cattgtacaa cctcggccct tcaccggaac cgaacctgac cgtactctgg
    12601 agcccggaac ttcccgaagg attcaaagaa ttctgtgcaa aggtttctat cgacacttct
    12661 tctatccagt acgaaaacga cgacctgatg cgtgaagtac gtcagtccga cgactacgga
    12721 atcgcctgct gcgtatcata ccaggaaata ggcaagcaga ttcagttctt cggtgcccgt
    12781 tgcaacctgg ccaaagccct gttgcttgcc atcaacggcg gacgttgcga gaataccggt
    12841 acagtcatgg tgaagaacat ccccgtactg accagtgaca cgctgaagtt cgaagaagta
    12901 atggacaact acaagaaagt actgatcgaa atcgcccgcg tatacaacga agcgatgaac
    12961 atcatccact atatgcacga caagtattat tacgagaaag cccagatggc tcttgtagat
    13021 acgaacccgc gcataaacct tgcttacggt gtagccggac tttctatcgc act
//
