LOCUS       c00037_gnlPro..        16735 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FLAMDBJK_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:45:00
            Original ID  :: gnl|Prokka|FLAMDBJK_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16735
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16735
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3221:6735]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3222..6735
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16735
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16735
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..92
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="NKLLIRILLHLQVEFSFYFNELKSGFKAE"
     CDS             234..1760
                     /locus_tag="ctg37_2"
                     /transl_table=11
                     /translation="MRTKRAFKEFCVLGGLASSVCGVAQERPNIIVFLVDDMGLMDTSV
                     PFIADESGQPVRHPLNDWYHTPNMERLAKQGICFSTFYAQSVSSPSRASIMTGQNATRH
                     GVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPRVLQQAGYKTIHVGKAHFGCMGSEG
                     ENPLNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTI
                     EANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMD
                     KSLGDIMDQLEKLGIAENTLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRV
                     PFIAAWAKPEKKSKVQKNLPIEVGSMQTQLGTIMDIYPTVLSVAGCEVPQNYVIDGFDL
                     KKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLK
                     DDPEERNELSAAHPDQCREMIREMSARLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(1832..3061)
                     /locus_tag="ctg37_3"
                     /transl_table=11
                     /translation="MNKLLLIWIVVLLTSCITNQENARDTLFVNLTDATDSQSLKLSDF
                     GNTVRYVPLETNEVCLIGNNPHIALLEDKIVIATKDQCFLFHKQTGKYICSIGHIGDDP
                     SGYSSTNYWIDDAGLFYFFRAPDQLLKYNQKGEMTGKIQIPHIPAAPDFFAFSDSTIIA
                     HCNSSIGLESSNSLLFLNSFGEKLDSIPNLLKSPSIPSPDNISSLSIIKRGAGFFGNLG
                     RRGVMIIKDKEQGELLLPLYNPSLWSSENEVRFRETFTDTIYTVKNRKLYPYMVFHTDT
                     DHSSANPLWYSNPQSIYVAYVLENTHSVFFQYVKNKQVYNGLYNKETQQTKFAKCQQFI
                     VDDLTSEQELKVDLSALCSYKGEYGFILEAASIPDASQKQSDNKNENIPHWMSQLDEDA
                     NPVIAIVSDK"
     CDS             complement(3222..3977)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_4"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(4014..5993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.1e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2e-36, bitscore:
                     116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             complement(6031..6735)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_6"
                     /sec_met_domain="SucD_FumR (E-value: 4.8e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             complement(6856..7806)
                     /locus_tag="ctg37_7"
                     /transl_table=11
                     /translation="MEERILFSQKTTIFVPVDNDSRIKPMSKDSLCAQHTDCSGCPKAM
                     ESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTTLHEKQFILQAIGSKY
                     EILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVMNPRLFYLINDVAAYL
                     DESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTESFQYFVMQNYSKAKNV
                     EEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQHSNMRITEICNRYGFD
                     SLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             complement(8490..10073)
                     /locus_tag="ctg37_8"
                     /transl_table=11
                     /translation="LKKCNIYTYMNKLVLTGLLAAGTMTHLQGAQPAGQRPNILFILSD
                     DHTSQAWGIYGGVLAEYAHNANIRRLAKEGVVLDNCFCTNSISAPSRASILTGLYSHRN
                     RLYTLADSLDTSIPTLATLLQANGYHTGLVGKWHIQSQPQGFDYYSIFYDQGEYRDPTF
                     IESTDPWPGNHQFGERVLGFSTDLVTEKAIRWMKEQDGNQPFLMCCHFKATHEPYDYPI
                     RMEHLYDGVTFPEPENLLDWGPETNGRSFKGQTLEELERRWRIASQDPDKWWCRYPGLP
                     FSTEGMQRTAARRASYQKFIRDYLRCGATVDDNIGKLLKALDEMNIADNTIVIYVSDQG
                     YFLGEHGFFDKRMFYEESARMPFVIRYPNKVPAGKRLDDLILNVDFAPTLAEFAGVKME
                     NVQGDSFVSNLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYARNLDMTD
                     TENFDFTPSWDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLRKETGDTDGKYPEM
                     QELLEKYYNK"
     CDS             complement(10260..10355)
                     /locus_tag="ctg37_9"
                     /transl_table=11
                     /translation="MGFDRKSRYRQRKQMFKNHYNTSKNQHKVSY"
     CDS             10371..11336
                     /locus_tag="ctg37_10"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKGVTSWEELIKSVRADVKGTKTKLRLGA
                     ASGEWKAMVADEAARVAFAKNIKKILEKNKLDGIDLDFEWAETEKEYEDYSLAILKMRE
                     VLGDKYVFSVSLHPVCYKISKEAIAAVDFISYQCYGPSPVRFPMEKYCSDIQMALAYGI
                     PKEKLVAGVPFYGVTKDGSKKTEAYFSFVQDGLITGPAQNEVTYKGDVYVFDGQNNIRA
                     KTRYAMDQQLKGMMSWDLATDMPLNDSRSLFKTMVEELGR"
     CDS             complement(11305..15435)
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MKTYIAAFFLLLSATFAAAHPYLIQRLGIEQGLSNNYVLSITQDK
                     QGFLWFATEEGLNKFDGTRFITYYKEEQSSSVQSITGNELNEVYADPVQPVIWIATQRA
                     GLNAYNYETQSFSVYQYNPEDPQSLITNDVTHITSSVQAGKGLWVCTYYRGIEYLDIAT
                     GKFTHYNKSTVPALPSEQTWTATEAEDGKLYIGHVEGGLSILSLNDKSVKHFVHDPQNP
                     NSLPGNDVRCIYKDTNGNIWIGTSKGLALFNANTETFTNFHNNPGNIHGALSSYIFSIK
                     QLKDNKLWIATELNGIMILDLQQNQFLLPEQIRFEFIREGDNNYSLSNASARYIFQDSF
                     NNIWIGTWGGGINFISNAPPAFHTWSYSPTQMNESSLSNKVVSSVCDDGQGKLWIGTDG
                     GGINVFENGKRVAIYNKENRELLSNSVLCSLKDSEGNLWFGTYLGNISYYNTRLKKFQI
                     IELEKNQLLDVRVFYEDKNKKIWIGTHAGVFVVDLASKKVIHHYDTSNSQLLENFVRSI
                     AQDSEGRFWIGTFGGGVGIYTPDMQLVRKFNQYEGFCSNTINQIYRSSKGQMWLATGEG
                     LVCFPSARNFDYQVFQRKEGLPNTHIRAISEDKNGNIWASTNTGISCYITSKKCFYTYD
                     HSNNIPQGSFISGCVTKDHNGLIYFGSINGLCFFNPDIAINSPQIPPVVITKVRIPGRL
                     TSREKNETAIPISEGEIELTHEQNSFNLTFNVQDYSLANQVEYAYMLKGLENSWYTINE
                     QNSVTFRNIPPGKYEFLVKARLHNQDWSEDTTSLRIHINPPLWLTWWAKLIYILITISI
                     IYTIIHAYKKKIDLEILYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGPLED
                     MQKDTSLPTRQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVCKSNIAPLVHEI
                     GLKYKELNQKKAIDFQIQIEKEEMLLFFDKEIITIILDNLISNAIKYTEQGKITLSLYP
                     TTRNGVTYTEIKVSDTGYGISAEALPHVFDRYYQESGKHQASGTGIGLALVRNLVELHE
                     GEIRVESIQNEGSTFYISLLTDNIYPNALHGDSTKQTEEEMISEAVPEDSQNTEPETSK
                     PILLIVEDNEDIQKYIAESFSDSFEVITGSNGEEGKQQALNRIPDIIVSDIMMPVMDGI
                     TLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLD
                     SRKKLIAQFQQTGTSHNPNSHLDEKRSIITEALSKLDNEFIEKITQLVEDNLSSEKIDI
                     TYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKYNISEIAYKIGMN
                     STGYFRQCFKDEFGVSPSDYLKQFTSPTPPPSS"
ORIGIN
        1 taaacaaatt attaatcaga attctgttgc atttgcaagt tgaattcagc ttttatttca
       61 acgaattaaa atcaggtttc aaagcagaat aataacatga tagattatgc tgaatgaatg
      121 aaagataata ggatattttt ctaatactct tttgtgtaat cagaagagag tctgagtttg
      181 aaatctatta tggcacgtac aataactagg atataaatca taaatactat gtaatgagaa
      241 caaaacgagc ttttaaggaa ttttgtgtat tgggtggttt ggcatcttcc gtttgcggag
      301 tagctcagga gcgcccgaat attattgttt tccttgtaga tgacatggga cttatggata
      361 cgtcggttcc ttttatcgca gatgagagtg gtcagccggt gcgtcatccg ctgaatgact
      421 ggtatcatac cccgaatatg gagagactgg ctaaacaggg tatttgtttt tctacttttt
      481 acgcacagag cgtgagttcc ccttccagag cttccatcat gaccggacag aatgcgacca
      541 ggcatggagt cactaactgg attaatgctg agagcaacaa tcggaatcct ttcggaccgc
      601 cccaatggaa ctggaaaggt ctcagaaaag atatgcctac catgccgaga gtcctgcaac
      661 aagccggata taaaaccatt catgtaggaa aagcacattt cggctgtatg ggaagcgaag
      721 gagagaatcc gctgaatatc ggctttgatg taaatatcgc aggttccggc attggacatc
      781 ccggcagcta ttatggcgaa tggggatacg ggcatatcaa gggacagaag attagagcag
      841 ttcctgacct ggagaaatat cacggtacag ataccttcct gagtgaagcg ctgactatag
      901 aagcgaatcg ggagatcacc aaagccgtag aagaaaaacg acctttctat ctgaatatgg
      961 cccattacgc agttcattca cctttccagg cagacaaacg tttcttgtca cgctacaccg
     1021 acccggataa gaacgagcag gcaagagctt ttgctacatt gatagaaggc atggataaat
     1081 cattaggcga catcatggac caactcgaaa agctgggaat tgccgaaaat acgctgattc
     1141 tctttttagg agataacggt ggtgatgctc cattgggaga tgaacgtggc tatggttctt
     1201 ccgctccgct gagaggtaaa aaggggacgg agtttgaagg tggtatgcgt gttcctttca
     1261 tcgcagcttg ggcaaagcct gagaagaaga gcaaagtaca gaagaacttg cctattgaag
     1321 taggaagtat gcagacacag ttgggcacaa tcatggatat ctatccgact gttctgtctg
     1381 tggcaggatg cgaagttccc caaaactacg tgatagacgg attcgatctg aaaaagcaac
     1441 tgagcggtaa ggtggacaag aagcgtcccg agtctttcct gatgcacttc cctcacgcac
     1501 accgcggcag ctacttcacc acctatcgca tgggcgactg gaaactgatt tattattatc
     1561 ttcccgagac tccgaaacaa cccaaagcct tgctttacaa tctgaaagac gatccggaag
     1621 aaaggaatga gctgtctgcc gcacatccgg atcaatgcag agagatgatt cgggaaatgt
     1681 ccgcccggct agaaaaggaa ggagctcttt atccggtgga taaacaagga aatgagttga
     1741 agccttttgt ttacttttaa ataggtgcta ctatttcaac tgtctgtttt gccaaagcat
     1801 atctattagg caaaacagac agaattatat atcatttgtc agatacaatt gctatgaccg
     1861 gattggcatc ctcatccaat tggctcatcc aatggggaat attctcattt ttattgtcag
     1921 attgtttttg agaagcatca ggaatactgg cagcttccag aataaatcca tattctcctt
     1981 tataactgca caatgccgac aggtcaactt tcagttcctg ctctgaagtg agatcgtcaa
     2041 caatgaattg ctggcacttt gcaaacttag tttgctgtgt ttctttatta tacaaaccat
     2101 tatagacttg tttgtttttt acgtattgaa aaaatacaga atgtgtgttt tccaatacat
     2161 aagctacgta gatactttgc ggattactat accataaagg attggcggat gaatgatctg
     2221 tatctgtatg aaaaaccata tatggatata gtttcctgtt tttaactgtg tatatcgtgt
     2281 ctgtgaaggt ttctctgaaa cgtacttcat tctcggacga ccataggctg ggattataga
     2341 gaggcagcag taattctcct tgctccttat ctttgataat cattacccct cttcttccca
     2401 gatttccaaa gaaacctgct cctcttttta tgatagaaag gctggatata ttatccggag
     2461 aagggataga gggcgatttt aataaattgg gaattgaatc cagcttttct ccaaaggagt
     2521 tgaggaaaag caaagagttg ctggattcca atcctatact actattacaa tgggcaataa
     2581 tggtagagtc ggaaaacgcg aaaaagtcgg gtgcggcagg tatatgtgga atttgaattt
     2641 tcccggtcat ttctcctttc tgattatatt ttagcaactg gtccggtgcg cgaaagaagt
     2701 aaaaaagacc tgcatcatct atccagtaat ttgtcgagct atatccactt ggatcatcac
     2761 cgatatggcc tatactgcat atatacttcc cggtctgttt gtggaataag aaacattggt
     2821 ctttagtagc aatcacaatc ttgtcttcca gcagcgctat atggggattg tttcctatca
     2881 ggcatacttc gttggtttcc aaaggtacat aacgtacagt atttccgaag tcagataact
     2941 ttaggctttg ggaatcagtt gcatccgtaa gatttacaaa taatgtatcc ctggcattct
     3001 cctgatttgt gatgcatgag gttagtaaga ctactatcca tatcagcaat aatttattca
     3061 tcgtatttaa tttatttgat tgtctggcct tatgtcacaa agaaaagaat aaaaaacgga
     3121 taatgaacaa gctatctata aataattggt cagtaaaaag aaatcccccg ccagctaacg
     3181 ccgacggggg atttatgcta ttaatcaaat caagctcacg cttagtcttt cagtttagcg
     3241 atgatgaagt cgcggttcag gcgggcgatg ttgctgatag agatgttctt cggacattca
     3301 gcctcgcaag cgcgggtgtt ggtacagtta ccgaatccga gttcgtccat cttggacaac
     3361 atagctttcg cacggcgcag agcttccggt ttaccttgcg gaagcaagtt caactggctg
     3421 acctttgccg aaacgaacaa catggcagaa ccattcttac aagcagctac acaagcaccg
     3481 caaccgatac aagaagcggc atccatagct tcgtcagcaa tgggcttcgg gatcaggata
     3541 gcgttggcat cctgcggagc gcctgtacga acgcttacat aaccaccggc ctgcatgatc
     3601 ttgtcataag cagtacggtc taccatcaag tccttgatga cagggaaacc ggccgaacgc
     3661 caaggctcaa cagtgatggt gtcaccatcg ttgaaacgac gcatgtaaat ctggcaagta
     3721 gtagcacctg ttgcaggacc gtgcggatgt ccgttgatgt aaagagaaca cataccgcaa
     3781 ataccttcgc ggcagtcgtg gtcgaataca accggttctt ttctttcgct gatcagctgt
     3841 tcgttcagaa tatccagcat ttcgaggaag gaagtatcac cggggatatc tttcatttgg
     3901 taggtttcaa aagcgccttt agccttcggg cctgcttgac gccatacctt cagtgtaaat
     3961 gatatatttt tatccatttt cgtctaattc ttttaaatgt ttaacttcac cgattagctc
     4021 ttgtagttac gggtctgaac cttgatagct tcgtatacca gcggttcttt gatcaataca
     4081 ggagcctttt catcgtcacc ctgatattcc cagcaagcta cgtagaagaa gttttcgtca
     4141 tcacgttttg cttctccttc ttcagtctgg tattcttcac ggaagtgacc accacaactt
     4201 tcgttacggt tcaatgcgtc gtaagcaacg agctcgccca tagtgatgaa gtcatacaga
     4261 cggatagcct tgtcgagctc aacgttcata ccttccttag aaccggggat aaacagattg
     4321 gtttcgaatt ccttgcggac tgctttcagt tcggcgatac ctttcttcag gccttctgcc
     4381 gtacgtccca tacctacgta ttcccacatg atgtgaccca gtttcttgtg gatagaatca
     4441 actgattctt taccctggat gctcatgaac ttgtcgatct tagcctgaac tgccttttct
     4501 gcttcggcaa attccggaag gtcagtagag aaacgaggaa cagtaatctg atctgccaga
     4561 tagttctgga tagtgtaagg caatacgaag taaccgtcgg ccagaccttg catcaatgcg
     4621 gaagcaccga ggcggtttgc accgtggtcg gagaagttac attcaccgat agcgaacaga
     4681 cccttgatgg tagtctgcag ttcgtagtct acccagatac cacccattgt gtagtggata
     4741 gccggataaa tcatcatcgg attataatat ttcacaccac tgatttcttt tgccagttcg
     4801 cccggattaa cgtcagtgat ttcttcatac atatcgaaga ggttaccata acgctgaagc
     4861 actacatcga tgcccaggcg gttgatagct tcagagaaat cgaggaatac ggccagacct
     4921 gtgttgttca caccgaaacc tgcgtcgcaa cgttctttag ctgcacggct ggcaacgtca
     4981 cgtggaacca ggttaccgaa tgccggataa cggcgttcca gataatagtc gcggtcttct
     5041 tcaggaatat cgcttccctt gatttcgcct ttctgcaatt tgatagcgtc ttctttcttc
     5101 ttcggaaccc agatacgacc gtcgttacgc agagattcgg acatcagagt cagtttggac
     5161 tgcttgtcac cgtgtaccgg gatacaagtc gggtgaatct gaacgtatgc ggggttagcg
     5221 aatacagcac ccttgcggta gcaagagata gcagctgtac agttacaacc catagcgttg
     5281 gtagacagga agtaagcgtt accgtaacca ccggtagcga ttactacggc gtgagcagcg
     5341 aaacgttcca gttcgccggt gattaagttc ttggcgatga taccgcgagc acgtccgtcg
     5401 atgattacaa cgtcctgcat ttcataacgg gtgaacaact tcaccgtacc tacgtttacc
     5461 tgacggctta gtgcggagta agcacccagc aacagctgct gaccggtctg gcctttagcg
     5521 tagaacgtac gtgatacctg tgcaccacca aaagaacggt tgtccagtgt accgccgtat
     5581 tcgcgtgcga aaggaacacc ttgtgccacg cattggtcga tgatagcgtt ggacacttcg
     5641 gccagacggt aaacgttggc ttcacgtgca cgatagtcac caccttttac tgtatcgtaa
     5701 aacagacggt aaacggagtc accatcattc tgataattct ttgcagcatt gataccaccc
     5761 tgtgcagcga tagagtgtgc acggcgcgga gagtcctgaa tacagaagtt gaatactctg
     5821 aaacccattt caccgaggga tgcagcagca gaagcacctg ccagacccgt acccacaacg
     5881 atgatatcca aacggcgttt attagcgggg ttcaccaatt tctggtgagc tttatagttg
     5941 gtccatttct cagccaccgg gccttctgga atttttgaat ctatcttgat cataatatta
     6001 tttacaattt aatcatttac aatttactat ttagcaagca ccgccacaaa ggagtgattt
     6061 cacgaagaat accactacta cgagtgcgaa accgagtact acaatcgtag aatagatgtt
     6121 agaaatacat ttccaacgat tgatccatac cttgttgttc catcccagtg attgcatgga
     6181 gctccagaaa ccgtgagtca ggtggaacca cagagcaaac agccaaatga ggtagagcac
     6241 tacataaacc ggacaagaga atgtctgctg gatgtgatat gcaccgtttg ccgcataagc
     6301 cagcgtcagt gtatcagcgt gcatgtccag gttgtgcatc agttccggca actgcatttt
     6361 tgcccagaag ttgaagaggt gcaaaccgag gcctacgata acgataatgc ctaacaccaa
     6421 catgttttga gaagcccact ctacagtttt cggtttgtcg actactgcat agcgttcgct
     6481 accgcgcgct gtgcgattct gcattgtcag ccagaacgcg tagatgatgt gaataatgaa
     6541 aagagcagcc agtgctgcgg tagctaccag cgcataccag tttgctccca aaaactcaca
     6601 aatcatgttg taaccatcag ccgagatgat tgcaactaag ttcatcgcca tgtgaaatgt
     6661 tagaaacagg acaagggcga taccggtaac gctcatcacc actttccttc ctacagatga
     6721 attacttaac cacataaatg attgaattta aattatttaa ttgttagaac taaaatttcg
     6781 acgttttaca cctcttacag actgcaaaaa taggggaaat agattgattg accaaagaat
     6841 taaagaaata attccttaat cggtgatctt tccgattttt tcgccattgg ccgctttctt
     6901 gcgcaaggcg cgcggggtgt ctccgaagga gtctttgcag aagtgtgcaa ggtgggacag
     6961 cgagtcgaaa ccataccggt tgcaaatctc tgtaatccgc atattagagt gctgtaggtc
     7021 ttcgaggatg ccttcccgtt ttttctccag catccattcg tagacgggca cgccgtataa
     7081 gtttcggaag agacggcgga aggtggtggt gttatagcct cccagatgtg cgaattcttc
     7141 gacgttcttc gctttgctgt aattctgcat gacaaagtat tggaaacttt ccgtataggt
     7201 gctgatcggg tagaagaaag ccctcaactg gggcagggga tagtaattgg tgatcatata
     7261 caccatctcc tgacatttca ggtcgatata tttgccgcag gcgggtgtcg attcgtcaag
     7321 gtatgcggct acgtcgttga tgagatagaa caggcgcggg ttcatcacca ttggggtgta
     7381 ggtcagcggg ccttctgcct ggtcgatgat ttcacggtag cggttttcgc atagcaacgg
     7441 cagttcgttg aaccagaaaa ggatgtatga tacgtccgtc agtgccagta tctcgtattt
     7501 tgagccgatg gcttgcagga taaactgttt ctcgtgtagt gtcgttccgg gatgttcgtc
     7561 actgttgatc agcaattcgc cctcgatcat aaagagcatg cagttttgcg tgcacttatc
     7621 cttcggaata tgctgccctc tgagcagatt tctgtgaata agagtacttt ccatcgcttt
     7681 ggggcatcct gagcaatctg tatgttgagc acaaagtgag tcttttgaca tgggttttat
     7741 ccgtgaatcg ttgtctacag ggacaaagat agtcgttttt tgtgaaaata aaattctttc
     7801 ttccattatg ttttagcaga aacggggata tgattgtctt tattggtttt gtttgcacaa
     7861 ctttgaagtt tcacggactc ctgaatggcg ttctttaata cattaataca tttttatctg
     7921 ccatctgcag cattttcttc atccctttac atgatatatt cagaacaagt agtttcatca
     7981 ttagttccac ctgttgaaac caagtgtttc aaggcatgaa acaaactgtt tcaagtaatg
     8041 aaacttcttg gaacaactgt cgatttcgtt catatgacag ctcgattcaa ctcacttgac
     8101 cgcataagtt gctctgattg acctgtccgt tcgaaaggta ttatttcatt tttcagtcaa
     8161 taatggatga cttctcagct gttaatacct gatttctcaa ttattaatag ctgacatgac
     8221 aatcgttaat agctgacgcg tcagatgtta atacccagta aatcaaagta taatgtagga
     8281 taaacgacct atatgccgtg gtggcagagt gagagcaaac ctttgctctc actctgccac
     8341 catacttgct gtaatgcttg aaatgccgat gaataaaggg atacacgcga ataatgagag
     8401 cgttagggca aaactgctat ctttttcact tgtagcagct gcctaagttc aagttataaa
     8461 tgcgacagtt cagtttccgt accagtcact tacttattat agtatttttc aagcagttcc
     8521 tgcatttccg gatatttccc gtccgtatct ccggtttctt tgcgaagtct caataagtcc
     8581 ttcttcatct gtttgatgac aggtgcatat ttcggatcgt tgtatgcatt atgattctcg
     8641 tgcggatcgt tctgcaagtc atagaagtcc catgacggag taaagtcgaa gttctccgta
     8701 tcagtcatgt ccagatttcg ggcataatag aagatcagct tgtaacggtc tgaccggatg
     8761 gcgaagtgtg cgggacgaat agcgtgattg gtccagtagc gatagtagat ttcttttcgc
     8821 cagtcggtcg gcgtgttgcc ttccaggttg ctgacgaagc tgtctccttg cacattctcc
     8881 atctttactc cggcaaattc tgccagcgtc ggtgcgaaat cgacattcag tatcagatca
     8941 tccagacgtt ttcctgcggg gaccttattc ggataacgga taacgaaagg catacgagcc
     9001 gattcttcat aaaacatccg tttgtcgaag aagccgtgtt cgcctaggaa atagccttgg
     9061 tcggagacgt agatgacgat ggtattgtcg gcgatattca tttcgtccag agctttcagg
     9121 agtttgccga tgttgtcgtc gacggtagcg ccacaacgga ggtagtcacg gataaacttt
     9181 tggtaggaag cacgtctggc ggctgtccgt tgcatccctt cggtgctgaa cggcagtccg
     9241 gggtagcggc accaccactt gtcgggatcc tgtgatgcga tgcgccagcg gcgttccagt
     9301 tcttccagtg tctgtccttt gaaagaacgg ccgttggttt ccggtcccca gtccagcagg
     9361 ttttcgggtt cggggaaggt gacgccgtcg tagagatgct ccatgcgtat cgggtagtcg
     9421 tagggttcgt gcgttgcttt gaaatggcag cacatcagga agggttgatt gccgtcctgc
     9481 tctttcatcc atcggatggc tttctcggtg acgaggtcgg tggagaagcc gagcacccgt
     9541 tcgccgaact ggtggttgcc gggccacggg tcggtgctct ctatgaaagt cgggtcacgg
     9601 tattcgcctt gatcgtagaa gatggagtag tagtcgaatc cttgcggttg cgactggata
     9661 tgccatttgc cgacgagtcc ggtgtggtat ccgttggctt gtagcagggt ggcaagggtg
     9721 gggatggagg tgtccagtga gtccgcaagg gtgtacagtc tgttccggtg actgtataga
     9781 ccggtgagga tactggcacg gctgggtgct gagatagagt tggtgcagaa acagttgtcg
     9841 agcactaccc cttcttttgc cagccggcgg atgttggcgt tgtgggcata ttctgccagt
     9901 actccgccat agatgcccca ggcttgggag gtgtggtcgt cactcaggat aaaaaggatg
     9961 ttggggcgtt gtccggcagg ttgagcgcct tgcaggtgcg tcatggttcc ggctgccagc
    10021 agaccggtaa gtacgagttt attcatatac gtatagatgt tgcatttctt caaaagtcag
    10081 tctaagttag acggttgctt tcatgtagat aaatgatcat atgaactgat tttatgccta
    10141 aagatagtga ttgttattca ctttgtatta taatccggaa aacttttgcg atttaatgta
    10201 attgattccg gtaaaacact taattccctt tttaaaagga tgtttttgtt ttacatctct
    10261 caataagaaa ctttatgttg atttttggaa gtattatagt gatttttgaa catttgtttt
    10321 ctttgcctgt acctactttt gcgatcaaaa cccattaatt atcaattatt atgctactac
    10381 caagaaaaat tgtatttttc cttctcttgt ttgtcggatt atcgttgtat gcgcaacaaa
    10441 actgcttcat tagttcgtat gtacggggta atttctacaa tcgcggacgt atttctgccg
    10501 agagtttaag ggcgagtgat gatctgattt ttctgaacgt ccgtcccaat aaagatgggt
    10561 cgctttcgtt tgagaatccc cgtatctttg agaatgggaa aggagtgact agttgggagg
    10621 aattgataaa gtctgtccgt gcggatgtga aaggaacaaa gacaaaactt cgtctgggcg
    10681 ctgccagtgg cgagtggaaa gcgatggttg cagatgaggc ggcccgtgtt gcatttgcca
    10741 aaaacataaa gaagatactg gaaaagaata agctcgatgg catcgatctg gattttgaat
    10801 gggcggagac tgaaaaagag tatgaagatt acagtctggc tattctgaag atgagagagg
    10861 tattgggaga taaatatgtg ttcagcgtat ccctgcatcc tgtgtgttat aagattagta
    10921 aagaggcgat tgctgcggtc gatttcattt cttatcagtg ttacggtcct tcgccggttc
    10981 gcttcccgat ggagaaatac tgttcggata tacagatggc gttggcttat ggcattccaa
    11041 aggaaaagct ggtggcaggc gttcctttct atggcgtgac aaaagatggc tcaaagaaga
    11101 ctgaggctta cttcagtttt gtgcaggacg ggctgattac ggggccggca caaaacgaag
    11161 taacctataa aggagacgtg tatgtctttg acgggcaaaa taatatccgt gccaagacac
    11221 gttatgcgat ggaccagcag ctcaaaggaa tgatgagctg ggacttggct acggatatgc
    11281 cgctgaatga cagcagatcg ttgtttaaga cgatggtgga ggagttgggg aggtgaactg
    11341 cttcagataa tctgaaggag agacaccaaa ctcatcctta aaacattgac ggaagtagcc
    11401 tgtactgttc attcctattt tataggctat ttccgagata ttatattttc cttcgaggag
    11461 taaccgttcc gcattctgca tttttacttt ccggatgtat tcgttcgtag aaagtccggt
    11521 cagcgctttc atcttccggt agagcgtaga gccgctcata cacatcttgt cggacaggta
    11581 agtgatatcg atcttttccg aagaaaggtt atcctcaacc agttgtgtga ttttctcaat
    11641 gaattcgtta tccagtttgc tgagcgcctc ggtgattatg gaacgctttt catccaaatg
    11701 agaattgggg ttatgactcg ttccggtctg ctggaattga gcaatcagtt tctttctcga
    11761 atcgagcaga ttgttgatgc ggcttcgcag cagtgaagca ctgaaaggct tggtcagata
    11821 agaatccgct cccacttcgt atccttcttc tttatcctgc aatgaatctt tggccgttag
    11881 caggatgaca gggatgtggc tggtacgcac atcctctttt agttgacggc atagcgtgat
    11941 gccatccatt accggcatca tgatatcgct tactataata tcgggaatac ggttgagagc
    12001 ctgctgtttc ccttcctcac cgttgctgcc tgtgattact tcgaaagagt cggagaaaga
    12061 ttcggcgatg tatttctgta tatcttcatt gtcttctaca atcagcagga taggtttgct
    12121 cgtttccggt tccgtatttt gagaatcttc cggaacagct tctgatatca tttcctcctc
    12181 tgtttgcttc gtagagtctc catgcaaagc gttggggtag atattgtctg ttaataagct
    12241 gatatagaaa gtacttcctt cgttctgtat gctttccacc cggatttcgc cttcgtgcag
    12301 ttctacaaga tttcggacta aagccagtcc gatacctgtg ccggatgcct gatgcttgcc
    12361 gctttcctga tagtaacggt cgaaaacatg aggcaaggct tccgcagaga ttccgtatcc
    12421 cgtatcactg actttaatct ccgtataagt gactccgttt cgtgtggtgg gatacaagct
    12481 caaggttatt tttccctgtt ccgtatattt gatggcattg gaaatcagat tatcgaggat
    12541 aatggtgatg atttctttgt caaagaacag aagcatctct tctttttcta tttgaatctg
    12601 aaagtcgatc gctttctttt gattgagttc tttgtatttg agtccgattt catgaacgag
    12661 gggcgcgatg ttgcttttgc aaacacatag ctttttgttc tgcgtttccg ttttccggaa
    12721 ctcaagaatc tgattgatca ggttgagcag ccggagggca ctctggtgga tgacagaaag
    12781 tttctgcgcc tgtctggtcg gcagtgacgt gtctttctgc atatcttcca gcggaccgag
    12841 gatcagggtc agtggtgtgc gcagctcatg agtgatgtta gtatagaatc gcaaacgttc
    12901 ctgattcaat tcttgttctt gttcgtggtt tttcttttcc agggtataga gaatttcgag
    12961 gtctattttc ttcttatagg catggataat agtataaata atgctgatag tgatcagaat
    13021 ataaataagt tttgcccacc atgtcagcca gagaggaggg ttgatatgta tcctgagaga
    13081 ggtcgtgtcc tccgaccagt cctgattgtg caggcgggct tttaccagaa actcatactt
    13141 gccgggagga atattacgga aggtgacgct gttttgctcg ttgatcgtat accatgagtt
    13201 ttcaagtcct ttcagcatat aggcatattc cacctggttg gccagtgaat agtcctgtac
    13261 gttgaaagta agattaaaac tattttgttc atgagtcaat tctatctctc cttcggagat
    13321 gggaatagcg gtttcgttct tctcccgact tgtgagtcgt ccgggaattc tcactttagt
    13381 gataaccaca ggaggaatct gcggactgtt tatggcaata tcggggttga agaaacacaa
    13441 tccgttgata gagccgaaat agatgagccc gttatgatct ttggtaacgc atccgctgat
    13501 gaaacttcct tgtgggatgt tgttggagtg atcgtaggta tagaaacatt ttttagaggt
    13561 gatatagcaa ctgatgccgg tattggtact tgcccagatg ttgccgttct tatcttcact
    13621 gatagctctt atgtgtgtat tgggcagtcc ttcttttctt tgaaaaacct gatagtcaaa
    13681 attacgggcc gaaggaaaac ataccagccc ctcaccggtg gcaagccaca tctgaccttt
    13741 gctgctccgg tatatctgat taatcgtatt ggaacaaaaa ccttcgtatt ggttgaactt
    13801 cctgaccagt tgcatatccg gcgtatatat cccgactcct cctccgaaag ttcctatcca
    13861 gaaacgtcct tcactgtctt gggcaatgct gcgtacaaag ttttccagca actggctgtt
    13921 ggaggtgtca taatgatgaa tcaccttctt gctggcaagg tctacaacga acacccctgc
    13981 gtgagttcct atccatatct ttttattctt gtcttcatag aagacgcgta cgtcgagaag
    14041 ctgattcttt tccagttcga tgatctgaaa cttcttcagt cttgtattgt aatagctgat
    14101 gttgcccaga taggtgccga accataggtt gccttccgag tctttcagcg aacaaagcac
    14161 tgagttggac aggagttctc tgttttcttt attgtaaatg gccacccgtt ttccgttttc
    14221 gaatacgtta atacctcctc cgtcagttcc tatccacaat tttccttgtc cgtcatcgca
    14281 gacgctgcta acgactttgt tgctcagcga actttcattc atttgggtgg gtgaatagct
    14341 ccatgtatgg aatgcgggag gagcattgct gataaaattg attcctcctc cccaagtccc
    14401 tatccagata ttattaaaag agtcttgaaa gatataccgt gcgctggcgt tggacaaact
    14461 gtagttattg tccccttcgc ggataaactc aaagcgtatt tgttcgggca gcagaaactg
    14521 attttgctgt aagtccagta tcatgattcc gttcagttct gttgcaatcc agagtttgtt
    14581 gtctttgagt tgtttgatgg agaagatata gcttgacaat gctccgtgaa tattccccgg
    14641 gttgttatga aagttggtaa atgtttctgt attggcattg aacagggcta gtcctttgct
    14701 ggttccgatc catatatttc cgttggtatc tttatagata caacgcacat cgttccccgg
    14761 aaggctgttc gggttttgag gatcatggac gaagtgcttc acggatttgt cattcaggga
    14821 gaggatgctc aacccgcctt ctacgtgtcc gatgtatagt ttgccatcct cagcctccgt
    14881 ggctgtccag gtctgctcag agggaagggc gggtactgtg cttttgttat aatgagtgaa
    14941 tttcccggta gcgatgtcca gatactctat acctctgtaa taagtacata cccataaccc
    15001 tttgccggct tgtacggatg aggtaatgtg agtgacatcg ttcgttatca gactttgcgg
    15061 gtcttccgga ttatattggt agacgctgaa actttgtgtc tcgtaattat aagcgttgag
    15121 tcctgcccgc tgggtggcta tccagataac aggctgcacg ggatcggcgt acacttcatt
    15181 gagttcgttg ccggtaatgc tttgaacaga agaagattgc tcctctttat agtaggtgat
    15241 aaagcgggtt ccgtcaaact tattcagccc ttcttcggtg gcgaaccaca gaaatccctg
    15301 cttgtcctgc gtgatactca atacataatt gttggataag ccttgttcta ttcccaatct
    15361 ttggatgagg taagggtggg ctgccgcaaa tgtggcggat agcaggagga agaaagccgc
    15421 aatgtatgtt ttcatcgttt cagatattat gtattccttg atattcactc tcaaaagtac
    15481 aaataaatct tgtatttagt atagacaaat gattcattgc atgattttct accctttctg
    15541 catgattttt acagcgaata aaataaaaca actgtaattt tgcaatcaat caaataaccg
    15601 aatctaatac ttgcagaaaa tggaatctga ttctttacac gaacatgata aaagctggaa
    15661 ggcatttttt attaccactc tgttcatctt gtgtacagcg aacgtttatg cgcagtcatc
    15721 cgatacaatc ttttcccgat atttccgtta tgcacagaac ttcgcagatt cgtaccctcg
    15781 cgagaaagtg agtcttcatt tggataatgc aagttattac cttggtgata cgatttggtt
    15841 caaagcgtat gtagtgacgg ctgaacaaaa cttaccgacg acgatcagca aacctttgta
    15901 tgtagaatta ctggaccagt tgggaaatgt cgtagagcgg caaattattc agcttacgga
    15961 tggggaggga acgggacaaa tcattttgaa caataccttc tttaccggtt attatgaaat
    16021 gcgtgcctat acaaagtgga tgcttgcttt tgataaccct tcctgttttt cccgtgtatt
    16081 acccgtctat cggaaacggc tgagcgatga agagactcct cggagtatag ctacctatcg
    16141 tatggacgct tcgatgaaac agcggccgaa ggataaagag aagaagttta cagtccgctt
    16201 ttttccggag ggtggacaat tggtgaaagg catatcttcg attgtagctt ttgaagccac
    16261 cagccgtgac aaaggagctg ctgatgtaga gggaacagtg gttttgccga gtggtgaaga
    16321 actggcgcat atccgttcat tgcatgacgg gatgggttac tttgagtata agcccgaaga
    16381 aaaggcgggt gtggcaaaaa ttgattatga aggctccact tatcagtttg accttccgga
    16441 agctcttcca caaggatatg tactccgaat cgataaccgg cgggaaatgt tggatatcac
    16501 tgtagcccgc agttcacagg caatgaaaga cacactggct gtttttgtat cttctcaggg
    16561 gcgaccttac aaatgtatga cactggactt tgaagatgaa ttgaactgcc aattccggat
    16621 ttcgactaaa gaactaccgc ccggagtgca acagatatct ctggtcaatc tgaaagggga
    16681 aacgttatgc gagcgttttt gttatgtgat gccgcgttct tccatgctcc ttgcc
//
