LOCUS       gnlProkkaLDEMOHEN_105  12507 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDEMOHEN_105.
ACCESSION   gnlProkkaLDEMOHEN_105
VERSION     gnlProkkaLDEMOHEN_105
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:36:24
            Original ID  :: gnl|Prokka|LDEMOHEN_105
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 13496
            Orig. end    :: 26003
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12507
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12507
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(249..878)
                     /locus_tag="ctg105_13"
                     /transl_table=11
                     /translation="MEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVD
                     ALITREPGYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGT
                     SGEDVIACIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQ
                     ILAFGVPSGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(1058..2224)
                     /locus_tag="ctg105_14"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(2314..2883)
                     /locus_tag="ctg105_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(2943..3479)
                     /locus_tag="ctg105_16"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3520..5064)
                     /locus_tag="ctg105_17"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVVLIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5787..6011)
                     /locus_tag="ctg105_18"
                     /transl_table=11
                     /translation="MVVYLYHFLILIGHFVSSVSTLDEEWCRFFAERSQCVRTALVVEL
                     NLRIFIFQSDWRKVVIIVITAHEANNTKE"
     CDS             6027..6587
                     /locus_tag="ctg105_19"
                     /transl_table=11
                     /translation="MKAKEIGRASIKIEDSSNNMYILSVVVKYRTLTHKAFTAKVIVKG
                     DELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVL
                     DEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFLPLLNTRMNAHPLIQYCFVR
                     DLTAQYKQDYLALENAYLIQIAE"
     CDS             7053..8564
                     /locus_tag="ctg105_20"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8638..9702
                     /locus_tag="ctg105_21"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9724..10011
                     /locus_tag="ctg105_22"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_23"
                     /sec_met_domain="PF05402 (E-value: 2.4e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.9e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10393..11781)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg105_24"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSTVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(12072..12467)
                     /locus_tag="ctg105_25"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPVAE"
ORIGIN
        1 cgcttataag cctcacgggt agcagcaatc acaggttgca acttaatgtc tgccatttgg
       61 gtggtggtag tcaagtcttc tgtgaaaata tttatttctt tccaaagtcc atcgcaataa
      121 gcagtattct tcactgctgc atatacggct gctccggcaa aaacagggca ggcgttcttt
      181 atttcctgag atacttttat ttcaaacata cttttattca agtttatatc aacttacgtt
      241 caagtctatt atttatgaat catgatcccc gacagaatcc gtccggactt aatgcccaaa
      301 cgccttgccg agaaaaactc gtcgtgatga atatacgtac atatccgggc aagctccact
      361 tgtccggacg gcacaccgaa agcaaggatt tgcatccggt tcgcttccca caagtcgata
      421 tgatgttttc cggtttcctc tttcctgata gaaatacgag gcatatcaaa accattcttc
      481 tgaaatgctt cgtacacttc ctcacccact tcaaaagaag ccaatgagat actcggaccg
      541 atacaggcta tcacatcttc tccacttgtg ccaaactcct tctccatccg caacaaagta
      601 tcacgcacga tgtatgctac cgtccctctc catccggcat gaatggcagc tatggcacta
      661 tgtttcttat catatatcaa cacaggaaca caatccgcag tagaaataca aagacaatat
      721 cccggctcgc gggtaatcaa agcatccact ccgtgcagca tctcctgtcg ttgttgagac
      781 gaagccgata aataagcatc cccgatcagc aggcaattcg tctcatgagt ctgcacagga
      841 atcaccagtt cttcgggtgt ctgcgacatt ccttccatca gaagcgtttg attccgccag
      901 accttttccg cctcgtctcc actgtagggc gtacagttga atgacgcata atttccttcg
      961 ctgcaccctc cctgccgggt agttacaaaa tgagaaatgt tggagtatga gcttaacgac
     1021 tcatacccca acattctttt atctcttgtg attgaaatca tttttcttcc caatcctctt
     1081 cttcgtattc gtagtcgaga tcatcatcgt cgtcgtcagc gtcttcctca tattcatagt
     1141 cgagttcttc atcctcgccc atgtccttga gttcctgctg cagacgggtc acgtctttcg
     1201 gacggtgaac aatgtcttct atcttattac tttccttgtt cagttcctcc cacagaatgt
     1261 ctttcaacac tgagattccc aaaccagaaa cagaagaaat gaatatatgc ggaacaccct
     1321 cgggcaatgt cggttcaatc tcgtccatca gctcctgatc gagcatatcg ctcttcgtga
     1381 tagccagcac acgttgtttg tccagcattt cgggattgaa cgtacgcaac tcattcagca
     1441 atacttcata ctccttgcgg atatcatcgc tatctgccgg aaccatgaac aacagcaacg
     1501 agttacgctc gatatgacgc agaaaccgca gtcccaatcc ttttccctga ctggctccct
     1561 cgatgatgcc cggtatgtcc gccatcacga atgactttcc atcgcgatag gaaacaattc
     1621 ccagattcgg ttcgagtgtc gtaaacgggt aatcggcaat cttcggtttc gcagccgaaa
     1681 tagcagaaag caacgtagac tttcccgcat tcgggaaacc taccagccct acatctgcca
     1741 acagtttcag ctccatgatc accgtcattt cctgcatcgg ttcgcccggc tgcgcaaagc
     1801 gcggagcctg acgggtagcc gtcttgaaat gactgttacc ctgaccgcca cgaccgcctt
     1861 tcagcaagat cacttcctgt ccgtcgtccg tcacatcgca aaggtattct ccggtttcgg
     1921 cgttatacac taccgttccg cagggtactt cgatcacttt atccgcaccg tcttttccga
     1981 aactacggtt cttgctgccc gattcgccat gacctgccat cgcatgacgg tcatacttca
     2041 agtgaagcaa tgtccagtaa ttacggttac cgcgcaagat aatatggcct cctcttccac
     2101 catcgccccc atcgggacct ccgttaggac aatatttctc gcgcctcatg tgcgtagagc
     2161 ctcttccgcc cttacccgaa cgacagtata tctttacgta atcaacaaaa ttcgattcag
     2221 ccatattttt tttaaaagtt aaagtagcca gtagttagag cagttaatta gaacactccg
     2281 gctactgact tatttattta taatattgta ttattacaat ttatctactg cttcgcagat
     2341 ttcagcgaag ataccttcca tagtacccaa gccgttgatg tgttggtatt tcttttcgtt
     2401 cttgtaccag tcgatcagtg gagcagtctg tgaatgatat acatgcagac gtttcttgat
     2461 tgtttcttcg ttatcatcag cacgaccgga atccttacca cgtttaatga gacgtaccat
     2521 cagttcttct tccggaacat ccaagtcaac cattacagaa acgtcctgtc ctctttctgc
     2581 caacattttc tttaatgctt ctgcctgtgc aattgttctt gggaaaccgt cgaaaattac
     2641 acctttgcta tctttgaagc tgtcgaatac gcttgccaga atatcaatca ttaattcatc
     2701 aggaatcaat tgaccttggt cgatgtaacc tttagctgtt ttacccagtt ctgtgccatt
     2761 cttgatttca gcacgcaata catctcctgt cgagatgtga ttgattccat acttttctac
     2821 gatacgttcg ctctgtgttc cttttcctga acccggagca ccgaaaatta cgatgttcaa
     2881 cattttgtta tttacaattt aacgatttac tatttaccat ttaaactggt acctatttaa
     2941 tattaatcta ctactgtata aatatcggga taattacgtc cgaaaccatc ataatccagt
     3001 ccgtaaccta cgataaagtc gttcgggatt tccatcgcta catattcaat gttgaggttt
     3061 accttgagct tttcaggttt caccaacaga gaagcgatat gaatagcttc gggattgcgt
     3121 gtacctaatg tttcgagcag tcgctgcatc gtcagtcctg tgtctacgat atcttctacg
     3181 atcacaatgg tacgtccggc aatgtcttca ttcaggccga ttacctcttt aatcactccg
     3241 gtggaagtga tgccctgata agacgccaac ttcacaaatg agatttcaca agggatggtg
     3301 atgtgcttca gtaaatcagc ggtaaacatg aacgaaccgt tcaacacact aaggaaaagc
     3361 ggattcttac ctgctaaatc gcggttaatt tcgttcgcta cgcgaatcac ttctttctga
     3421 atttcttgtt ccttaataga aacggtaaac aatttgtctt ttatctgaat ggtatccata
     3481 accggtaatt taaaaataac cttgcaaaaa tacgattttt tattctaccc cgtgcatcat
     3541 cttctgtaat ttcttcgaga gaaggaacag aatcagtgag gcaacaccgg acataatgac
     3601 gaacagcatg aagaagtcgt acatggtagc aatctgataa ccaaggattg atttcacttt
     3661 tccgtcttcg ggatagagac cgctcagcat acctgcaaat ttatttgcgg tggcggtaga
     3721 aagataccag atccccatca tcaaggaggc gaaacgtaac ggactcaact tattaaccat
     3781 agaaagcccg ataggtgaca gagcgatttc tcccattgta tgaataaagt aaagccctgt
     3841 cagccagatc atgctcacct ttactcccgg aatagcatct ttcactccaa aacagatgaa
     3901 gagataacca agagaaagca gcaacagacc gattgcctgt ttggtagggg aagccggttc
     3961 catgtttcgc ttattcagaa agccccatat accgggcata atataggcaa ggatcactac
     4021 aaaaagcgga ttgaatgact ggaaccacga agccggcatc tcccagccga aaatgctgcg
     4081 gtcagtctgt tcggaagcga ataatgtcag agaagctcct gcctgctcgt aagctgccca
     4141 gaagaaaatg acgaagaaag ctacgatata gattacgaaa atacggctac gttctacttt
     4201 ggtcaatgaa ccatccagca gaatgagcac tggaaagaca atacaagccg taaagatacc
     4261 cacactaatc cagtcatcgc taaaggcata gctaaaaaag gctattaaga caactgtaag
     4321 ggcagtaatg atgataatat tacgtacttt ggtacgtttg tccatcttcg gatgtgaaat
     4381 atgttcggct ttatcctcct ttttttcacg tctggcgtcg gggacgatac caatcggttc
     4441 accggaagga gagaaaaggt atttattctt ctgagtttca aagaggacaa cagtgaacag
     4501 cgtcatgatt ccggatgcga ggaatcccca tttaaagtcc tgcggattcc ctgtgtctcc
     4561 caagaaaccg caaatcaaag gagcagcgaa agaacctaca ttaacaccca tatagaaaat
     4621 ggtgtatgca gcatccaacc gtttgtcccc gggttcatat aattgcccga cgagcgaaga
     4681 aacggtaggc ttaaagcaac cgttacctaa aatcatgaat ccgagtccgc catacatcag
     4741 ccagtgggca aggtctgtat tgttcagtga agaggcactc ataaacatca ggaactgacc
     4801 gactgccatc atcaccgctc cccaaaatac cgaacgacgg atgccccaat atttatcggc
     4861 aatgtatccg ccgatcaacg gagtcagata gaccagtccg gtgtagctac cgtagataga
     4921 ggccgccgct tctttatcaa aaagcaatgc ctgcgtcaga aagaggataa agatagcacg
     4981 cataccgtag taactgaaac gttctgccgt gctcgttgcg aaaattaggt aaaggccttt
     5041 cgggtgccct ttcaatgaac tcatgaatta tgtgtttagt agtttatggg gtgcaaaggt
     5101 actaaaaagt agattaaatg cctcaaaaaa gaagattctt atggaataga aaaatacagg
     5161 atggcgtgca aaaagtctca gttacccacc ttattatgtt ttcaacagtg taaataatca
     5221 agtggatatt ctccttaaat gtgggtcagt ccccatttat ccaaaggtaa attcaacatt
     5281 ctcaatactg gcatagagca ttccttcttt ttttctaagc aggattttgt tttcccttgc
     5341 cagccaaccg atagcaattg ctacatcctc gaacgtcaaa cctaactcat ggcacaaagt
     5401 gaacatagac tgttcgccct tttcatttaa gatgcgccat actttcccgg catttgagcc
     5461 aattcttttc ttttccatca tgcaaacttt agaagattaa acaatttata tttataatct
     5521 aaacattgtg agcacaggag aataacgtaa agcacattac tgcactacaa agatatcatt
     5581 tttttcgaaa aaagcaaata atcaaggcat tagctgctat tattagttac attctaatca
     5641 tttatgccga tctctgctaa aaaatagcac aaataaagaa acagttcaat tctttttcat
     5701 aagtttgcag acgagaacta aactaatatc gcacatttaa aactttaatt agcatgacta
     5761 ccaaaaaact aacaggaata ctttcgttat tcctttgtat tatttgcctc gtgagctgta
     5821 atgacaatga tgacaacttt tctccaatca ctctggaata tgaagatcct caaattaagt
     5881 tcgacaacga gagccgttct tacacactga ctccgttcag caaagaaacg acaccactct
     5941 tcatcaaggg tggagacgga acttacaaag tgaccaatga gaatgagaaa gtggtacaag
     6001 taaactacca caacggaagt ttaacattga aggcaaagga aataggacgc gcatccatca
     6061 agatagaaga cagttcgaat aatatgtata tactgtctgt cgttgtaaaa tatcgtactc
     6121 ttactcataa ggcgtttaca gcaaaagtca ttgtgaaggg agacgagctt acatctgaag
     6181 aacacactga gttaatgaac aaagtgggca attcatatcc gattaataaa tatgtattta
     6241 cttttatgaa tgcggaagac agcaaaggaa cagtagattt gtattattca gataataaca
     6301 tgaaaacagg caactttgaa aaagaacata tagtgctgga tgaagaaaat gccattccca
     6361 tcaaaggtga atacaaattg agtgagtatt atcgtataac aatcaaagaa gataatggca
     6421 aagttattga tactttctat attaccaaga actttctacc actcctcaat acaagaatga
     6481 atgctcatcc gttaattcag tactgttttg tcagagattt aaccgcacag tacaaacaag
     6541 attaccttgc actggaaaat gcatatctga ttcaaatagc agaatgagaa ctacactgat
     6601 tttcttcttt agcagagtga atagagtatt tattatatga gcaaactccc cattagattt
     6661 agcaaaaaac aataagctat tagctaatca agaatatgcc catagcatat ttatcacaat
     6721 cacctcttcc acccttttcc tgaacctttg atgaataagg cgattgcggg tgaaagaggt
     6781 gaaccagagg aatatacagt agtagaaaca cgcatgggaa ggttaacaaa cagccatgaa
     6841 tgttctccgg agagagtaaa agtaaatgag ataacaatca ttaatatctg acttctcaac
     6901 tattaataac tgacacatca actattaata cctgacaact caagtattaa tacctgaagt
     6961 tccttcccaa aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggaac
     7141 gtgccgcaca ggcactgact aaagccatca ccaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgccagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg gctgatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcactgatc aaaccacgcc aacaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcccgtg
     7861 cctgtctgcg atcgggagta ggtctgctga cggtacacgc gccgttatgc aacaacgata
     7921 ttctgcaaac gtccgccccc gaagccatgg tagaaacaga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca
     8041 acgaagaaac ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac
     8101 tggatgccga cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtgacttg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaatg tcccctacag cagtaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
     9361 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
     9481 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgcttat cattatgggc
     9961 gtactgatag gatgtgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatattg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
    10141 ctatcaggtt ccatacggcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggt atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
    10381 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
    10441 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
    10501 catcggcaag gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
    10561 gttcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
    10621 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
    10681 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
    10741 ccaccatata ttcagaatag gaagagcgaa catcgtgtgt acgaaaatca gcatcaccga
    10801 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tataatgaac cgaacaatgg
    10861 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
    10921 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
    10981 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttggtaa tgatatagac
    11041 aatgtctttc atgcggaaag gttcttccgg ttccagtcct tccgcatcca gtgaagcatc
    11101 cagtttctta tcgtagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
    11161 gagacagaac agaatcggag cgggaatatt ggtatggaat acgccgctct catccgtaga
    11221 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagttgttc caatacgcgc
    11281 ggtcgccatt tccagtccca tagcgagagc catctctttg cctttaaacc acttcacgat
    11341 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccgaaaatag cataacccaa
    11401 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
    11461 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
    11521 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
    11581 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
    11641 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
    11701 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgtggagt cattcagctt
    11761 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
    11821 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
    11881 gacatctgac cggatattcc tgtatgaaga agagcagacc gggcccaata ataaagacag
    11941 acgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
    12001 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
    12061 ctgtcactga attattctgc tacaggagca ggagtttcag tagccggagc ttccgttgct
    12121 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
    12181 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagctgca
    12241 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
    12301 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
    12361 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
    12421 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
    12481 gaattagcgt taataatcaa tttctcc
//
