LOCUS       gnlProkkaJLAAJOJE_145  27219 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JLAAJOJE_145.
ACCESSION   gnlProkkaJLAAJOJE_145
VERSION     gnlProkkaJLAAJOJE_145
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:23:13
            Original ID  :: gnl|Prokka|JLAAJOJE_145
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 27219
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1032)
                     /locus_tag="ctg145_1"
                     /transl_table=11
                     /translation="MATKIKLNDCVPCIAIHPGEIIKDELDAREMKQKELASLMSMPTS
                     VLNDIIKGRRAVTPEVAVLLQEILGIDASYWLSLQNQYDIDRANINKKIVERKKNIEIW
                     KVISQYCSVKYFEKLNVIGTKISENIKIIYSIFGVTSVEELIASFSSEKELSYFKKSER
                     LKSDPINIFSWKHFAFYQSSQMLDVADFDENSLERLVQELNQMFVVNINTIDKTKEILS
                     RYGIKFIIVPKFDKTPIDGFSFWQGKNPTIVLTLRLNKIDNYAFALLHEIYHVYMHLFN
                     NREQKYIAIEGAEINKCEEEANKFAKCSLIGKDLWNTFLKQHSMISPHAMQMKIKQFAH
                     QHNI"
     protocluster    1..27219
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7011:17219]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7012..17219
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..27219
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..27219
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1022..1345)
                     /locus_tag="ctg145_2"
                     /transl_table=11
                     /translation="MNIYTEDEALIELLEEGCTNDKRYKRLPKDVIKGYIKAYNHLKAA
                     TRIEDLFRIGSLHYERLKGDLKDFESVRCTGRWRLIFQSSTIDGSLIITEIELIEISNH
                     YGD"
     CDS             complement(1649..2779)
                     /locus_tag="ctg145_3"
                     /transl_table=11
                     /translation="MAVINPFVVGGYVSPRYFCDRVAETENLIRNLINGRNVALVSTRR
                     MGKTGLIRHCFYQPLIKEGYYTFFIDIYATSSLKEFVFALGKGIFEKLKPQGNKFIDRF
                     FSIITSLRIGFKLDSITGEPILELGLGDIHAPETTLEEIFIYLEQADKPCIVAIDEFQQ
                     ISSYPEKNLEAILRTKVQHCSNSNFVFAGSQRHIMMNIFNSPSRPFYQSVSMMHLGAIP
                     LEVYKPFVKGLFEENGKKVTDQLVENVYTLFDGHTWYVQLMLNELFILTDKKGICDVPM
                     INLALNNIIATQDFTFQEIFSRLPEKQKEIMIAIAKEQKAKGVTSAAFIKKYRLTSASS
                     VQSGLKGLLEKDMLTQESGGYQVYDRLFNIWLRRNY"
     CDS             complement(2820..3776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_4"
                     /sec_met_domain="Glycos_transf_4 (E-value: 9.7e-30,
                     bitscore: 95.6, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCYLLILVLLFLAELFYFRIADKCNIIDKPNERSSHTRITLRGGG
                     IIFYLGALTFFLTNQFEYPWFILALTLITFISFIDDIRSTSHGLRLVFHFTVMALMFYQ
                     WGLFSLPWWTLLVALIVCTGIINAYNFMDGINGITGGYSLVILVSLAYVNAEVISFTEQ
                     SFIYTMICSVLVFDFFNFRKRAKCFAGDVGSVSIAFVVLFLIGSLILQTKDFSWLVMLT
                     VYGVDSVLTIIHRLLLHENIGLPHRKHLYQIMVNELRIPHVVVSLVYMIVQIVIIIGYL
                     YCRGYGDWYLLGCILLLSGIYIVLMRKYFHLHLLPKR"
     CDS             complement(4005..4280)
                     /locus_tag="ctg145_5"
                     /transl_table=11
                     /translation="MIHGIRNGKYLSIAGGEARKSVLMVQDITNLVPLLIEKGGIYNVC
                     DSYQLSFRELEMVICKQLNKKRPISIPYCLLKVWPFLVIVLGKMPQ"
     CDS             5066..5629
                     /locus_tag="ctg145_6"
                     /transl_table=11
                     /translation="MAQLESKQLNKIGLHENATNRNMDEKLLLKCENSIRAYKIVNLLN
                     KHNIALRQHDESQDPRVGAYGAVTGIAIYVFAKDYEKALSIVSPILKDFNTISTFCPKC
                     GSENVKPITGNHKYITYLIFLCLFLILTPGIYIALPEDFGLRSSLINKIALMMVVLGFI
                     LMPIINHYNVNYKCKKCGNRFRHY"
     CDS             5580..5681
                     /locus_tag="ctg145_7"
                     /transl_table=11
                     /translation="MLIISVKNAAIDLGIISFIVHNRFYCFITTESS"
     CDS             complement(5662..5817)
                     /locus_tag="ctg145_8"
                     /transl_table=11
                     /translation="MDRILIEYITERSSFHLFQIDSDVYISRNFKPHNKNIYYIGQSLF
                     INLILL"
     CDS             5967..7040
                     /NRPS_PKS="Domain: PKS_ER (37-231). E-value: 1.3e-20.
                     Score: 65.6. Matches aSDomain:
                     nrpspksdomains_ctg145_9_PKS_ER.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 104.3; E-value: 1.2e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_9"
                     /sec_met_domain="ADH_N (E-value: 3.8e-08, bitscore: 25.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIIVCDSNINKKDIEGYKVVIDGYEYLFALLDIPVNKYTDKIS
                     DQSVVVRVSAFSCNYRDKGILYNFLKKCKDYNLKESYYYSFLGSEFVGKVIKIGRNVRS
                     FKIGDRVMSDNSYPFKVDGKIGGIVSNYASKRIQIFHESCLIKVPDSMSDIEAAAFSLT
                     ASTAHSMVSKSKLKEGDKVLVTSLFSNTSLGCLELLKNISGIKIYGLTTGYKEAQSLSE
                     KFKIQKIFTPDDFYTATNKMNINFNVIIDPFPDIHINYLHSYLNYSSRYISCGMSSHQN
                     EKIDFYKILYSLIVSNSQFIGNCLGLPYDLKAVINEYSHERYKVYVDSVYTGRQISDFI
                     NKSFNERHFGKVVYSYE"
     aSDomain        6078..6659
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg145_9_PKS_ER.1"
                     /evalue="1.30E-20"
                     /label="ctg145_9_PKS_ER.1"
                     /locus_tag="ctg145_9"
                     /protein_end="231"
                     /protein_start="37"
                     /score="65.6"
                     /tool="antismash"
                     /translation="NKYTDKISDQSVVVRVSAFSCNYRDKGILYNFLKKCKDYNLKESY
                     YYSFLGSEFVGKVIKIGRNVRSFKIGDRVMSDNSYPFKVDGKIGGIVSNYASKRIQIFH
                     ESCLIKVPDSMSDIEAAAFSLTASTAHSMVSKSKLKEGDKVLVTSLFSNTSLGCLELLK
                     NISGIKIYGLTTGYKEAQSLSEKFKIQKIFT"
     CDS             7012..8256
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     198.9; E-value: 2.2e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_10"
                     /sec_met_domain="LANC_like (E-value: 3.1e-40, bitscore:
                     129.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLYILMNSLNINVCKVMKRKTLIEEDKKKIEISNKIDEIYLIM
                     KENVHCNNWGVLDGFSSTILFLSRLYIYSKDDKILDDLYNRINLLISYLDKIKLPTICG
                     GYAGICWLFRYLYKEKLVESNNINEVLDGLEKYITKTFYNYYINDTDFLHGGLGIAFYF
                     LLSDTNYSENLCKVYLDRLDKNKQNQKDGSCMWTTQVYNGGENEAVANLSLSHGMASII
                     IFLAYYHSKTNNPKAKRLLQQAIEFYKRNTNPNNFYSMYSNWIKINSPSNLSESRLAWC
                     YGDLGIAKALNYAGVSLGNSDITNFSFEVLNKTIPRFMNSHVEDASFCHGSSGISHIYN
                     HFYQITGYDAYKNSAIFWLNDTLNRIKYLEVNSSFSTELNDVCSILTGLSGVGLSLLSS
                     IEDKEDNWNELLLLL"
     CDS             8234..10429
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     400; E-value: 3.2e-121)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_11"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-123,
                     bitscore: 405.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.7e-10,
                     bitscore: 31.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYYYYCNLNLYKMNKYIPYNQCIIRTPLFPINYIDKIEDFELSI
                     FQQSFKEAVYIATPVLYQELYIKNNINERTINSAIKYYVRSCTRCTPYGIFAGCDIVPI
                     RIDDNYSNIIMSDLKNYKTYTRIDMNYLCELIRKLDLMPQIQNAITYHVNTTSYFLGKN
                     LRYIEYRINKSKRNYTFSEISHTPYLNNIIKALKKTPLTKKEIIRLLIKNKEIEEEEAL
                     NFVQTLIDEQILISNLEPSVVGEDLIQQLHHNLSEINYNLEFINSLIYLLKECDKESLG
                     NKESIINNIYRLLSDGMLFEQDTLMQVDTLNKVKQGIIGNNITKVIDKCIYFFSKFQPS
                     HKSETFELFKRRFYEKYEEQEVPLVVALDPQVGIGYGNWTENNGDINPLLQGLPNPFLD
                     RSYKIDMDLTPVTMLLIKKYEEAIKQGLHEIEILDEDLNEFEERDLKLPQCSVMLSVLS
                     NDDTPSILLKGIIGGATSRLISRFEYLDSKIENFVNEINKRDELYYKDCIVAEVMHLPE
                     DRIGNIQMHPNNRQYGICYLSSPTTKYVKKIIPIDDITISVYHGQEVILKSKKNKKRII
                     PMLSTAHNTKNGLPIYSFLSDYINQESMSYSFDWGSYFHNKSFLPRVIYSNVILKPARW
                     LIHPNEFPQNKNLNSDELYSWKLKQRIPDEILITLGDNQLYINFNKEHLVKIFISELKK
                     KRPIILEEFLYSSKNINLVESQEGFFANELIINLYKK"
     CDS             10426..11268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_12"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.5e-37, bitscore:
                     120.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQRIFIIGGEWIYFKIYSGPKTIENIFINDIMCKINLLIKQRMI
                     DSFFFVRYMDPNYHIRLRLHCTNINNYAFILHLIYKTLNRYVKDLIITKVQLDTYTREL
                     ERYEYNEIVHFETFFYYDSCLITKCLKRLNCTDQDRYKISMKFIDSIMDICNFSLDEKI
                     NFTEKNSKAYFLELYQSDCTIGHILNLKYRKYRNEIEKCLNDESKHCWWNKEIKKNIYI
                     MRTIPLNILTGKNNKLSSIIHMHVNRMYRINQRTVELVIYWYLNKYYRSKKAILCNLK"
     CDS             11278..11835
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_13"
                     /sec_met_domain="LANC_like (E-value: 3.9e-06, bitscore:
                     17.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNKMGKTIALFRLYRNTKEEEWRIRAEEMLDDIWNECTKDMSLA
                     YRDGLCGIGAGTEYLIQNGFVEGNTDEILAEIDSRVFAAINVRPPFDLSIEQGILGLAC
                     YLYHRLYYRKDSEEPTVLDLKEYTIYLIDWIAEALQDNSTDKDYYEFYFILVLLHTLNI
                     MNAKIENLLECCDKKLLTSVYK"
     CDS             11839..12609
                     /locus_tag="ctg145_14"
                     /transl_table=11
                     /translation="MEPISIVIPVRIDSTERKENLHCVLQYLLQTPFIYIDILEADQKQ
                     HFHFHPHERIRYRFIQDYETVFYRTRYLNILLKDARHVIVGIWDTDVLVPEKQLMDAIN
                     YIQKGCVLSFPYDGNFRFLDKEESQSIRKDITILHEGMGHRLIGRPSVGGAFLVNKTKY
                     LETGGENEGFYGWGPEDVERVKRLEILELPIARTKGALYHLHHERKPDIGVDNRKKARH
                     NQKVLLNTCRQSKEELTKALKNHTGIFFYLENHN"
     CDS             12617..14380
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 65.1;
                     E-value: 1.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_15"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-16,
                     bitscore: 52.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIAFLSSLNPRDIHNWSGTLYYMYHHLEKDHRLTWTGWQQYEEA
                     IKFHRENFGEDPPFSPEKYAQLFGKMLTDLFHYEYYDLIICRDYFFLAYLTTDIPVVYI
                     GDTTCRLFNQYLKIADSPKLDLAEKLEERSIQKATHIVYASEWAKNSAINHYHATPEKI
                     SVIEFRANIDNIPEYTDHDCISVCNLLFIGKNWEMKGGNKTIEIFYSVKKKGIPCTLTI
                     IGSTPTQIPKDTDIVVYPYIDKSSSEGQKLFEQILSQSHYLIAPTLFDCFGIIYCEASA
                     YGIPVLTTDVGGISQAVHNGYNGFLFTADTPASEYADKIIDLYMNKDMYTNLRRECRKH
                     FETRLNWNVWKKRMNDLLISIKEREEGTYIPVYVINIKEREERRKHIVREFEGKSEFEF
                     HLVEACTHSKGTIGLWNSITKVIKMAKEREDDVIVICEDDHFFTENYSSGLLFKEIQEA
                     YMQGAELLSGGIGGFGQAVPVGYHRYWVDWFWNTQFIVIYSSAFDTILSYEFQENDTAD
                     GVLSKIIHNKMVIYPFISEQKDFGYSDVTLGNMEYPGKIREFFTRTNAKFKMIRTIQEL
                     SVLEYCIKYTL"
     CDS             complement(15199..16446)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 99.1;
                     E-value: 5.2e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_16"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.5e-27,
                     bitscore: 88.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQHIFIINEKNLASSYGVGTYINEYIKCLRRFDLEIHLVTLFCD
                     EELYNLYENEFVDYINIPTTILKNTKYYHQSVCAIIKLYYAKIEKPLFHLNFHQNIFFV
                     KYIKDYFNDAIILYTIHYSCWSLQLNSDVNLFKSILSKYNSNGNLSELEHRVILEFEKE
                     KELFNKVDRIICLSNETYEILKSEYLISPTKINLIPNGIEDSYTPLLGNQKNIIRKYFH
                     IKKKEKIILFVGRLTALKGAYILLDSFKKISPYHTNYRLFIIGDGDFNLLLNQAEPYWD
                     RITFTGKIDKEKLNQLYKIADIGIIPSYCEQCSYVCLEMMMNAIPCIVSDGIGLNSIFK
                     NNINSIVAKIVDYQNPDSYILNLEKSILDMINNASKKDNISKKSRLTYLEKFTLDHMFE
                     NYKKLFLTFNIRVKEW"
     CDS             complement(16536..17219)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_17"
                     /sec_met_domain="LANC_like (E-value: 1e-08, bitscore: 26.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNSFYLEDAEIIKQLFLKSPHLQSNSLYKGKMGIVLFLYEFANL
                     TQNDAFKRFASFLLDLLWEDIEMDSPINLALGLSGIGVGIELLSQRKFIDCNNTSELCF
                     ELNNQIMTQNIYRLTDYTFETGLSGIIYYVLIHIKNNRHHSFDKVFLSEIFEKCIQIDQ
                     AKLNEISKFYISYYLDYFKGEKNNNLNPQLSHFINKKSVKNLKSMDDMGLYEGIVGYLY
                     LKYFL"
     CDS             complement(18559..19443)
                     /locus_tag="ctg145_18"
                     /transl_table=11
                     /translation="MKNTFILLLYVCISLGANAQLLWQISGNGLTKPSYVFGTHHLSPL
                     SILDSIIGFKQVMNDVEQVYGELVMDDMKIPINMQKVQQATLLPGDTTLQTLMTEAQYD
                     SIALKIKQLMGVELKMMNKLKPAALTSQIAVILAMKSMNNFNPQQQLDGWIQTEARKQG
                     KKVYGLETIDIQIKVLFNSQSLQRQAEQLFCTLMHLDLLDQMYQKMTIAYLNQDIDLIE
                     KIMKEKMDNACDFFPEEEEELNYGRNANWVKLMPPIMKEKSTLFTVGSGHLPGKLGVLN
                     MLGKQGYTIKPVK"
     CDS             complement(19901..20143)
                     /locus_tag="ctg145_19"
                     /transl_table=11
                     /translation="MTDATIATESVTGNSVQTLYADGVYGETNRAFVKKHGMDFITTGV
                     QGKTGRFDFEMTGKALQVTNKKTGEVIPVEKQEGK"
     CDS             complement(20443..20676)
                     /locus_tag="ctg145_20"
                     /transl_table=11
                     /translation="MDSRLIGSNIAWYSRYQLVYETFLKCINEDTTNPFPSKLKEKVLV
                     LLHKNAKSVIYTSVQDTIAAKLQNIEAGYFQR"
     CDS             complement(21466..21609)
                     /locus_tag="ctg145_21"
                     /transl_table=11
                     /translation="MLELCWCPNRVDTVAKDLRDYFKQFVDEDDVSHCFANKINEMPLE
                     LQ"
     CDS             complement(24264..24485)
                     /locus_tag="ctg145_22"
                     /transl_table=11
                     /translation="MVLDSLMLQSSKISRYGFSRRLYVILACCGNGLGHEVHAVRVLVC
                     NLVSTDLSKAAYRSMRCLSYPSYDRAHI"
     CDS             24654..24863
                     /locus_tag="ctg145_23"
                     /transl_table=11
                     /translation="MQTIRKDIEQTEAIIVDLTSRIKVVLSPYENVLKLLSPGLSRKTV
                     EDLIAEIGVDMEAFPTEKASDLVG"
     CDS             complement(25676..25852)
                     /locus_tag="ctg145_24"
                     /transl_table=11
                     /translation="MDSQRVCLGNHRSLNGGIDGNKKVKGVKCHVVVDKNGFLLAVMVT
                     IACVHNSKLFIYW"
     CDS             complement(25886..26143)
                     /locus_tag="ctg145_25"
                     /transl_table=11
                     /translation="MYSTWLEETQWQVIKKILNLQERKRKYDLREMWNAIFYVVKIGCQ
                     WRMLPSDFAPWELAYYYYCRYSSLGEFELLLNNLREKVHL"
ORIGIN
        1 gatattatgt tgatgagcaa attgttttat tttcatttgc attgcatgtg gagatatcat
       61 ggaatgttgt ttgaggaatg tattccataa gtctttacca attaaagaac acttggcgaa
      121 tttatttgct tcttcctcgc atttatttat ttcagctcct tctatggcaa tatatttctg
      181 ttctctattg ttgaaaagat gcatataaac atggtatatc tcatgcaata aagcgaaagc
      241 ataattatca attttgttta atcgtaatgt taatacaatg gttggatttt ttccttgcca
      301 aaaagaaaat ccatcaatcg gtgtcttgtc gaatttaggc actatgataa atttaattcc
      361 atatcgtgat agaatttctt ttgtcttatc aatagtgttt atgtttacaa caaacatttg
      421 attcaattcc tgcacaagcc tttctaaact gttttcatca aaatcggcaa catccagcat
      481 ttgtgaactt tgatagaaag caaaatgttt ccatgagaaa atgttaatgg ggtcactctt
      541 taaccgttca gatttcttaa aataagaaag ttccttttct gaagaaaacg aagctattag
      601 ttcttcaact gaagttacac cgaaaattga atatattatt tttatgtttt ctgatatttt
      661 cgttccaata acatttaatt tctcgaaata tttaacagaa caatattgag aaattacttt
      721 ccatatctca atattctttt ttcgttctac tattttctta tttatatttg ctcggtctat
      781 atcatattga ttttgtaatg ataaccaata tgaagcatct attcctaaaa tttcctgtag
      841 caaaacagca acttcaggag ttacagcacg acgtcccttt ataatatcat tgagtactga
      901 agtaggcatg ctcataagtg aagccaactc tttttgcttc atttctcttg catccaattc
      961 atccttaatg atttcacccg gatgaatggc tatacaaggt acgcaatcgt ttaatttaat
     1021 tttagtcgcc ataatggttg gatatttcta ttaattctat ttcagtaatt atcaatgaac
     1081 cgtctattgt ggagctttga aatattaatc tccaccgtcc ggtacatcta accgattcaa
     1141 agtcttttaa gtctcctttc aatcgttcat aatgcagact tccgattctg aataaatctt
     1201 ctattcttgt ggctgctttt aaatgattat atgcttttat ataacctttg attacatcct
     1261 taggaagtct cttgtatctt ttgtcgttgg tgcaaccctc ttccaacaac tcaattagtg
     1321 cttcatcttc tgtatagata ttcatgcaat tcgttatctt tctgcaaaga taaggatttt
     1381 attcttttcg ataatatata ccataaaata aattatcaaa tttgataatt acgcaatatc
     1441 gtttctcaaa aaaaaacaat aagaaaggat atattgtttc gtgaaaaaca acttttcaaa
     1501 attattagta tataaatgat tggcaaacca tttaattcaa ttcatatgct gcatttattc
     1561 tcaatacgtc cctgtccatc ctccaagttg attatttcaa acctgtcctc ttccgcgaag
     1621 atggttaaca ctgatgtttc cggttaaatc agtaattcct cctaagccag atattgaaaa
     1681 gtctatcata cacctgatac cctccagact cctgagtcaa catgtctttt tccagtaaac
     1741 ccttcaaccc cgactgcacc gaactggcag aagtcaaccg atatttttta ataaatgcag
     1801 cagaagtaac tccttttgct ttctgctcct tggcaatggc aatcattatc tctttttgct
     1861 tttccggaag acgagaaaat atttcttgaa aagtaaagtc ttgtgtagca attatattgt
     1921 ttagtgccag atttatcata ggtacatcac agataccctt tttgtctgtc aaaataaaaa
     1981 gttcattcaa cattaactgc acataccaag tgtgcccatc aaacagggta tatacattct
     2041 ctaccaattg atctgtcact ttcttaccat tctcctcaaa caatcccttc acaaaaggtt
     2101 tatatacctc caaaggaatt gctcctaagt gcatcatact cacgctttga taaaatggcc
     2161 tggaaggact gttgaatata ttcatcatta tatgcctttg acttcctgca aaaacaaaat
     2221 tagagttact gcaatgctga actttagtcc ttaaaatagc ttccagattt ttctccggat
     2281 atgaactgat ttgctgaaat tcatctattg ctacaataca aggcttgtct gcctgctcca
     2341 gatagataaa gatttcttct aaagtagttt caggagcatg aatatctccc aaaccaagtt
     2401 ctaaaatcgg ttctcctgta atactatcta atttaaatcc aatccttaaa gaggtaatta
     2461 tagaaaagaa acgatctatg aatttattcc cctggggctt taacttctca aaaatccctt
     2521 tacccaaagc aaaaacaaac tctttcaaac ttgaagtcgc atatatatca ataaagaaag
     2581 tataatagcc ttctttaatc aaaggctgat aaaaacaatg ccttatcaat cccgtttttc
     2641 ccattcggcg agttgaaaca agagccacat ttctcccatt tatcaagtta cggatcaagt
     2701 tttctgtttc agcaactcta tcacaaaaat aacgaggaga aacgtatcct ccaactacaa
     2761 aaggattaat aacagccata acaaaattat catatttata attattgcaa atataataat
     2821 tatcttttag gtaaaagatg caagtgaaaa tatttgcgca taagaacaat atatattcca
     2881 ctcagcaaaa ggatacagcc caataaatac caatcaccat aaccccggca atataaatac
     2941 ccgatgataa tcacaatttg cacaatcata tacaccaacg ataccaccac gtgcggtatt
     3001 ctcaattcat taaccatgat ctgatacaaa tgtttccggt gaggcaaacc aatattttca
     3061 tgtagcaaca accggtgtat gattgtcaac acactatcca ctccatatac agtaagcatc
     3121 acaagccagc tgaaatcttt cgtttgaaga atcaaactcc cgatcaggaa caggactaca
     3181 aaagctatac tgaccgaacc cacatcaccg gcgaagcatt tcgctctctt acggaaatta
     3241 aagaagtcaa acaccaacac agaacaaatc atcgtataaa taaaactctg ttctgtgaag
     3301 gagatcactt ctgcattcac atatgccaaa gaaaccagga taaccaatga atacccgccg
     3361 gtaatgccgt taatgccatc cataaagtta taggcattga taatccccgt acagacgatc
     3421 agagcgacaa gcaacgtcca ccaaggcaag ctgaacaacc cccattgata gaacatcagg
     3481 gccattaccg taaaatggaa gactaaacgc aaaccatgcg aagtagaacg gatatcatct
     3541 ataaaactga taaaagtgat caaggtcaaa gccaatataa accaaggata ttcaaactga
     3601 ttcgtcagaa aaaaagttaa tgcacccaaa tagaagatga ttcctccacc tctcagagta
     3661 atccgagtgt gtgaactccg ctcgtttggc ttatcgataa tattgcattt atcagcaata
     3721 cggaaataaa aaagttctgc caggaatagc agaactaaga ttagcagata acacataaac
     3781 tattcgttct ttttaatgaa ataaaaccaa agttgaagtc ctaaaaaggc aaaagaaata
     3841 ccccctatta ggagtcctat aatcccccaa aaatccactc acaatacctc cttattctat
     3901 ctgaaaattc tccaaaacat tcataggttt ccacccaagt tcacgcatag ccttttcatt
     3961 actaagagtc aaagagtgcg tgatcttacg aagttttaaa ctgtttattg gggcattttc
     4021 cccaagacaa tcaccaaaaa tggccatact tttagcaaac aataaggaat agatattggt
     4081 ctttttttat tcaattgctt acatatcacc atctctaatt cacgaaaact cagctggtaa
     4141 ctgtcacaaa cattatatat ccctcccttt tcaatcaata gaggaacaag attagttata
     4201 tcctgaacca tcaaaacact tttccgagct tctcccccag caatacttaa gtacttacca
     4261 tttctaatcc catgaatcat cgctcctaaa tttcccggag gattaggtcc ggcaatttag
     4321 gctactattg acggaacgat agattcagac gcaatgctga ataattactt atacgacttc
     4381 ttgtcgcacg agatacctaa agagacaaaa aatcaaatga ttttcaacaa tttgattatg
     4441 agtaaattgt aaaattttat aatattttct cataactacg gtgttgcatt gatactgtta
     4501 cactattggt aagtgatgta cttcctagta aggctacacc attggattaa ttcttttatt
     4561 tgctcagaaa gagcgagaaa aatcttcagc ttaatctaat aaatgattcc tgtttgctgc
     4621 agaaaaaatt tcttcctagt aaagatggaa ctcgaagagg tgtaatacaa aagaaaaaaa
     4681 tacaagaagc ataaaaagaa agaaaagcct attctcaaac ttattgatcc gcctttcctg
     4741 ttggtagagg agattcatct tagcatgaaa aagacaatag ataaaaaacg gtattcagaa
     4801 agatcgtttt gctaaaatca gaacgagtat tagttcttgt ctacaacttt aaattttatt
     4861 tacagaataa tatattttaa aacaaaatct aagtaataat tggaatatga actataaaaa
     4921 tcaatattct ttttgtaacc tgattttttc gtaagataga caaaagtgtt aaattacgca
     4981 aaatacatca gcatatattt ataatcaaat ttattttgac tatattagaa aaatgttcct
     5041 tcaatcttta aatataatat gaacaatggc acagttagaa tctaaacaat taaacaaaat
     5101 tggtttacat gagaatgcta ccaatagaaa catggatgaa aaattattat taaagtgcga
     5161 aaatagtatt cgcgcttaca aaattgtgaa tttgctcaac aagcataata ttgcattacg
     5221 acagcatgac gagagtcagg atcctagggt tggtgcatat ggcgccgtaa ctggtattgc
     5281 tatatatgta tttgctaagg attatgaaaa ggctttatct atagtttccc ctattcttaa
     5341 agattttaat accatcagta cattctgtcc aaaatgtgga agtgaaaatg taaaacccat
     5401 tactggtaat cacaaatata ttacttattt aattttcctt tgcctgttcc ttatacttac
     5461 tcctggtatt tatattgctt tgcctgaaga ttttggactc aggtcttccc taataaataa
     5521 aatagcttta atgatggttg tgctaggttt tattttaatg ccaattatta accattataa
     5581 tgttaattat aagtgtaaaa aatgcggcaa tagatttagg cattattagc tttattgttc
     5641 ataatcgatt ctattgtttt attacaacag aatcaagtta ataaaaagag attgtcctat
     5701 ataataaatg tttttattat gaggtttaaa attccgactt atgtatacat cactatctat
     5761 ttgaaataaa tggaatgagg atctttcagt tatatattct ataagtattc tatccattag
     5821 gaatcattac ttaaaaataa aaatatactt aagtttgact cgtttttatc caaaagtata
     5881 atagatagga tatatttcta tttttataga actccaagaa tgctgattta attgagaaaa
     5941 tgtaaattga taaataaata aaaaacatga aaaatataat agtctgtgat tccaatataa
     6001 ataaaaaaga tattgaaggt tataaagtag taattgatgg ttacgagtat ttatttgctt
     6061 tgcttgatat tccggtaaat aaatacaccg acaaaattag tgatcagtct gtagttgtta
     6121 gagttagtgc tttttcatgt aattacagag ataaaggaat attgtacaac tttttaaaaa
     6181 aatgcaaaga ttacaattta aaagaatcat attattattc atttctggga tctgaatttg
     6241 tgggtaaagt cataaaaata ggtaggaatg tgcggtcttt taaaattggt gatagagtta
     6301 tgtccgataa tagttatcct tttaaggttg atggcaagat tggtgggatt gtcagcaatt
     6361 acgcatcaaa acgtatacaa atatttcatg aatcatgtct aataaaagtt cctgactcta
     6421 tgtctgatat agaagcagct gctttttcac tgactgcttc taccgctcat tctatggtgt
     6481 ctaagtcaaa attaaaagaa ggggataagg ttctagtgac atcattgttc tccaatacat
     6541 ccttaggatg tttggaatta ctcaaaaata taagtgggat aaaaatatat ggattaacaa
     6601 ctggatataa agaagctcaa tcattatcgg aaaaatttaa aattcaaaag atattcacac
     6661 cagatgactt ttatactgca acaaataaaa tgaatatcaa ttttaatgtg ataatagatc
     6721 catttcctga catacatata aattatcttc attcatattt aaattattct tcacgataca
     6781 tatcatgtgg aatgagttct caccaaaatg agaagataga tttttataaa attttgtata
     6841 gcctgatagt atccaattcc caatttatag ggaattgcct aggattacca tatgatctta
     6901 aagctgtaat taatgagtac agtcatgaac ggtataaagt gtatgtggac tctgtataca
     6961 ctggaagaca aatttctgat tttataaata aatcctttaa cgaaagacat tttggaaaag
     7021 ttgtatattc ttatgaatag tcttaacatt aatgtatgta aagttatgaa aagaaaaaca
     7081 ttaattgaag aagataagaa aaaaatagaa atatctaata aaatagatga aatatacctt
     7141 attatgaaag aaaatgttca ttgtaataat tggggagttt tagatggctt ttcgagtact
     7201 attttatttc tgtcacgctt atacatctat tcaaaagatg ataagatatt ggatgattta
     7261 tacaatagaa ttaatttatt aatatcttat ttggataaga taaaacttcc tactatatgt
     7321 ggagggtatg ctggaatatg ttggctattc agataccttt ataaagaaaa attagttgaa
     7381 agcaataata ttaatgaggt cttagatgga ctagagaaat acataacgaa aacattttac
     7441 aattactaca taaatgatac agatttttta catggaggat taggtattgc attttatttt
     7501 ttactttctg atacaaatta tagcgaaaac ctttgtaaag tgtatttgga tagacttgat
     7561 aaaaacaaac aaaatcaaaa agatggaagt tgtatgtgga caacacaagt ttacaatgga
     7621 ggagagaatg aagctgttgc aaatcttagc ttatctcatg gaatggcttc aataattata
     7681 tttcttgcat attatcatag caaaacaaac aatcccaaag ccaagagatt attacagcaa
     7741 gcaatagaat tttacaaaag aaacactaat cccaataatt tttattccat gtatagtaat
     7801 tggattaaaa taaactcacc tagtaacctt tcggagtcta ggttagcttg gtgttacggt
     7861 gatcttggca ttgcaaaagc attaaattat gcaggagtat cattgggtaa tagcgatatt
     7921 actaattttt cttttgaagt tttaaataaa acaataccga ggttcatgaa tagccacgtt
     7981 gaagatgcat ctttttgtca tggttctagt ggaatttctc atatatataa tcatttttac
     8041 cagataacag gttatgacgc atataaaaat tctgcaatat tttggctgaa tgatactctt
     8101 aatagaatta aatatttaga ggttaactcc tcatttagta ccgaacttaa tgatgtttgt
     8161 tctattctaa caggattgtc tggtgttggt ttgtccttac tatcttcaat agaagataag
     8221 gaagataatt ggaatgaatt attattatta ttgtaattta aatttatata aaatgaataa
     8281 atatattcct tataatcaat gcattattag aacaccgtta tttcctatta attacattga
     8341 taaaatagaa gactttgagt tatcaatatt tcagcaatca tttaaagaag cagtttatat
     8401 tgcaactcct gttctctacc aagaattata tataaaaaat aatataaatg aaaggactat
     8461 aaattccgct ataaaatatt atgtccgtag ttgtacaaga tgtacaccat acggtatttt
     8521 tgcgggttgt gatatagtac ctattagaat tgatgataat tattctaaca taattatgtc
     8581 agaccttaaa aattataaga catatacacg tatagatatg aactatttat gtgaacttat
     8641 aagaaagtta gatttaatgc cacagataca gaatgcaatt acatatcatg taaatacaac
     8701 ttcgtatttt ttaggtaaaa atttgcgcta tattgagtat cgcatcaata aatctaaacg
     8761 gaattatacc ttctctgaaa tttctcatac accatattta aacaatataa taaaagcatt
     8821 aaagaagacc cctttaacaa aaaaggaaat aattaggcta ttgataaaaa ataaagaaat
     8881 agaagaggaa gaagctttaa attttgttca gacacttatt gatgaacaaa tcttaattag
     8941 taatttggag ccatctgtgg ttggcgaaga tttgattcaa caattgcatc ataatctttc
     9001 agaaattaat tataatctag aattcattaa ttctctcata tatttattaa aagaatgtga
     9061 caaggaatca ctaggaaata aagaatcgat tattaataat atataccgtt tattatcgga
     9121 tggtatgtta tttgagcaag atactctaat gcaagtagat actttaaata aagttaaaca
     9181 aggcataata ggaaataaca ttactaaagt tattgataaa tgcatatact tcttttcaaa
     9241 atttcagcca agccataaat ctgagacttt tgagcttttt aagaggagat tttatgaaaa
     9301 gtatgaagag caggaagtac cactagttgt agcattagac ccacaagtag gaattggtta
     9361 tggaaactgg actgagaaca atggcgatat aaatccttta ttacaagggt tgcccaatcc
     9421 ttttttagac cgatcttata agatcgatat ggatctgact ccagtcacga tgttgctaat
     9481 aaaaaagtat gaagaggcta taaaacaagg attgcatgag attgaaatac tagatgaaga
     9541 tttaaatgaa ttcgaagaac gtgacttaaa acttcctcag tgttcagtca tgctctctgt
     9601 tttatcaaat gatgatacgc catctatttt attaaaaggg ataattgggg gtgctacttc
     9661 tagattgatt tcaagatttg aatatttaga ttctaaaatt gaaaattttg taaatgaaat
     9721 aaataaacgt gatgaattat attataaaga ttgcatagtc gctgaggtaa tgcatcttcc
     9781 agaggataga attggaaata ttcaaatgca tcctaataat agacaatatg gaatttgcta
     9841 tttatctagt ccaaccacta agtatgtaaa gaagatcata ccaattgatg atataaccat
     9901 ttcagtgtac catggacaag aagttatatt gaaatcaaaa aagaataaga aaagaattat
     9961 tccaatgtta tcaactgcac ataatacaaa aaatgggctt ccaatatata gctttttatc
    10021 agattatata aatcaagaat ccatgtctta ctcttttgat tggggatcat attttcataa
    10081 taaatcattt ctcccaagag ttatctattc taatgtaata ctaaaaccag ctagatggtt
    10141 aattcatccc aatgaatttc cacaaaataa aaatttaaat agcgatgaat tgtattcttg
    10201 gaaactaaaa cagagaatac cagacgaaat attaataact ttgggggaca atcaattata
    10261 tataaatttc aacaaagaac atcttgttaa aatttttatt agtgagctca agaaaaagag
    10321 accaattatt ttagaagaat ttctatatag ttctaaaaat ataaatcttg ttgagtctca
    10381 agaaggtttt tttgctaatg aacttataat aaatctatat aagaaatgac acagcgtata
    10441 tttataatag gaggagaatg gatatatttt aaaatatatt ctggaccgaa aacaatagaa
    10501 aatattttta ttaatgatat tatgtgcaag ataaatcttc ttataaaaca gagaatgata
    10561 gattcattct tctttgtaag atatatggat cctaattatc atattaggtt aagattacat
    10621 tgcactaata taaataatta tgcatttatt cttcatctta tttataaaac tcttaaccgt
    10681 tatgttaagg atttaatcat aactaaagtt caattagaca cttatacaag agaattggaa
    10741 aggtatgaat acaatgagat agttcatttt gagacttttt tttactacga cagctgtttg
    10801 attactaagt gtcttaaaag actaaattgt acagaccaag atagatataa aatatcgatg
    10861 aagtttattg attcgattat ggatatatgt aattttagcc ttgatgaaaa aattaatttt
    10921 acagaaaaga atagtaaagc atatttttta gaattatatc aatctgattg tactattggg
    10981 catatattaa atttgaaata tagaaaatat agaaatgaaa ttgagaaatg tttgaatgat
    11041 gagagtaaac actgttggtg gaataaagag ataaaaaaaa atatatatat tatgagaact
    11101 attcctctaa acatcttgac cggtaaaaat aataaacttt ctagcataat tcacatgcat
    11161 gtaaatcgta tgtatagaat taaccagaga actgtagaat tagtaattta ttggtattta
    11221 aataagtatt atcgttcaaa aaaagcaatt ctatgtaatc taaaatgaaa agagtttatg
    11281 cttaacaaaa tgggaaaaac gattgccctg ttccgattat accgtaatac aaaagaagaa
    11341 gaatggagga tacgggcgga ggaaatgctg gatgatatat ggaacgaatg tactaaagat
    11401 atgtcattag catatagaga cggtctgtgc ggaataggag caggaacgga atatctgata
    11461 caaaatggtt ttgtggaagg aaacacagat gaaattctgg cagaaataga cagtagagta
    11521 tttgctgcta taaatgtccg cccaccattc gatttaagta ttgaacaggg aatattagga
    11581 ctagcttgtt acttatatca tcggctttac tatagaaaag attccgaaga accgactgta
    11641 ttggacttaa aagaatatac tatctatctc attgactgga tagctgaagc cttacaagat
    11701 aattctacag acaaggatta ttatgaattt tattttattt tggttttatt gcacacactg
    11761 aatataatga atgccaaaat agaaaatcta ttggaatgtt gcgacaaaaa gttattaacc
    11821 tcagtatata agtaaagaat ggaacctatc agcattgtta taccagtgag aattgattct
    11881 actgaacgaa aagaaaatct gcattgtgtc ctacaatatc tattgcagac tccttttatc
    11941 tatatagata tattggaagc cgatcaaaaa caacatttcc atttccatcc acatgaaaga
    12001 atccgctacc gctttattca agattatgag accgtatttt atcggacacg ttatcttaat
    12061 attttattaa aagacgcacg tcatgtcatt gtaggtattt gggatactga cgtacttgta
    12121 cccgaaaagc agctaatgga tgccatcaac tatattcaaa aaggctgtgt attaagcttc
    12181 ccttatgatg gtaatttccg ttttttggat aaagaggaaa gtcaatcaat cagaaaagat
    12241 attacaatat tacacgaagg aatgggacat agactgatag gacgcccatc ggtaggagga
    12301 gcctttcttg tgaataaaac taaatatttg gaaacaggag gtgagaatga aggtttctac
    12361 ggatggggcc ccgaagatgt agagagagta aaaagactgg agattttgga attgccaata
    12421 gcaagaacta aaggagcgct ttatcatctc caccatgaaa gaaaaccaga cataggagtg
    12481 gataatagaa aaaaggcacg gcataatcaa aaagtacttc taaatacttg ccgacaaagt
    12541 aaggaagagt tgacaaaagc actgaaaaat cataccggaa tattttttta tttagaaaac
    12601 cataactgaa accattatga atatagcatt cctttcctcc ctgaatccga gagacataca
    12661 caactggtcg ggaacattat attatatgta tcatcatttg gaaaaagatc atcggctaac
    12721 ttggacaggt tggcagcaat atgaagaagc tatcaaattc caccgggaaa acttcgggga
    12781 agaccctcct ttttcaccag aaaaatatgc ccaactattc ggaaagatgt taaccgattt
    12841 attccattat gaatactatg acctgattat ctgccgggat tatttctttt tagcctatct
    12901 gacaacagac atccctgttg tatatatagg tgataccact tgcagactat tcaaccaata
    12961 tctgaaaatc gcagattccc caaaactcga tttagccgaa aagctggaag aaagatcaat
    13021 ccaaaaggca acacatattg tatatgcttc cgaatgggcc aaaaacagtg ccatcaacca
    13081 ttaccatgca acacctgaaa aaatcagcgt tatagagttc agagccaata tagacaacat
    13141 ccctgagtat actgatcatg attgcatatc tgtctgcaac ttgcttttta taggtaaaaa
    13201 ttgggaaatg aaaggtggaa ataagactat tgaaattttc tattctgtaa aaaagaaagg
    13261 aatcccatgc acattgacta ttattggaag tacacctaca caaataccaa aggatacaga
    13321 tattgttgtt tatccttata tcgacaaatc atcatctgaa ggacaaaaac tttttgaaca
    13381 aatactcagc caatcccatt atctgattgc tcccactctg tttgattgtt tcggcattat
    13441 atattgtgaa gcctccgcct atggcatacc tgtactaact accgatgttg gaggtataag
    13501 tcaagctgtc cataatgggt acaatggatt cttatttact gctgatactc cggcatctga
    13561 gtatgcagat aaaatcatag atttatatat gaataaagat atgtatacca atctcagaag
    13621 agaatgtaga aagcattttg aaacacgctt gaattggaat gtttggaaaa agcgcatgaa
    13681 cgacttgctt atttccataa aagagaggga agaagggact tatatccccg tatatgtcat
    13741 caacataaaa gaaagagagg aaagaaggaa acatatcgtt cgtgaatttg aaggaaaatc
    13801 ggaatttgaa tttcatcttg tcgaagcatg cacccactcc aaaggtacga ttggactttg
    13861 gaacagcata acaaaggtga taaagatggc taaagagcgg gaagacgatg taattgtcat
    13921 ctgtgaagac gaccacttct ttactgagaa ttattcatcc ggactgttat ttaaagaaat
    13981 ccaggaggca tatatgcaag gagccgaact tttatccgga ggtatcggag gattcggaca
    14041 agccgttcct gtcggatatc atcgttattg ggtagactgg ttttggaata ctcaatttat
    14101 tgtaatttat tcatctgcat ttgacacaat tctgtcatac gaatttcaag agaatgatac
    14161 tgccgacgga gtattatcca aaatcattca taacaagatg gtgatttatc catttatttc
    14221 ggaacaaaaa gattttggat attcggatgt caccttggga aatatggaat acccgggaaa
    14281 aatcagagaa tttttcacaa ggactaacgc caaattcaaa atgatacgta ccattcaaga
    14341 attatctgta cttgaatatt gtataaagta cacattgtag attcataaag acagtcaact
    14401 ctttttgtta acaaatgcaa agttgatgag aaggttttac cgtcttatta aattctcatc
    14461 aaactccaat tggcttttta tcaaatttct tcaacttcca gacatcagga agcaagtcgc
    14521 gcacattctt tgccgactcc tctctccaac tagtacgaaa gttagggtat gacatcattc
    14581 agccattctc ctggattggc tgaatgcgcc ttgcaggtgg caagcaatga acaatcgctg
    14641 tattttctac agctccgtga ctgtcaaagt ggattctaat accggaaaaa aattctatga
    14701 ttacttcggt aattacaact tatgagagac gactactgtg acccaggtct aaaggaatat
    14761 atatcattgg gagctttatc tgaatggctg gtataagcac agctcaaacc aaacttctac
    14821 ttccaataat ggaaacaaga tactgaatag gcttcattct cacagaaatc cttatggcca
    14881 aggcactgga ctgttttttt cataactctt ttactcattg tacgtttcat cgtctttttt
    14941 acatgcaaag caacagaaga gttcttgact ttacaatgtg tactttatcg gatgcttaca
    15001 atattttaga tgttgcaata tgggattact gaatgcttac acataaaaag catctgactt
    15061 actcttttaa aaatagacca ttgtcttaaa cgacagttta aaccattaca accaccataa
    15121 tctcacatcc actatataaa ttcttcaaca ctacttggga gcttattcga agaataattt
    15181 ataacaaaca ctctattatt accactcttt tactcttata ttaaatgtaa gaaataattt
    15241 tttatagttc tcaaacatat gatccaaagt aaatttttct agatatgtta atcttgattt
    15301 ttttgatata ttatcctttt tactggcatt attaatcata tctaaaattg atttctcaag
    15361 attaagaata tatgaatcgg ggttttgata atcgacaatt ttagcaacaa tactgttaat
    15421 gttatttttg aaaattgaat ttaaaccaat tccatcagag acgatacaag gtatcgcatt
    15481 catcatcatt tctagacaga cataactaca ttgttcacaa taagatggta taattccaat
    15541 atctgcaatt ttatatagtt gatttaattt ctctttatct attttacctg taaaggttat
    15601 tctgtcccaa taaggctctg cttgatttag taataaatta aaatcgccat cgccaattat
    15661 aaataatcta tagtttgtat gataaggaga tattttcttg aaactatcta ataatatata
    15721 tgctcctttt aaagcagtaa gccttcccac aaaaagaatt atcttttctt tttttttaat
    15781 atgaaaatac tttctaataa tatttttttg attgcctaaa agcggagtgt atgaatcttc
    15841 aatcccatta ggaattaaat taatttttgt tggactaatt aaatattcac ttttcaaaat
    15901 ttcatatgtc tcattagaaa ggcaaataat cctatctacc ttattaaata attctttttc
    15961 tttttcaaat tctaatataa cacgatgctc taactccgac aaatttccat tactattgta
    16021 tttagataaa atcgatttaa acaaattaac gtctgaattt aattgtaagc tccaacacga
    16081 gtaatggatt gtatataaga taattgcatc attaaagtaa tctttaatgt atttgacaaa
    16141 aaaaatattt tgatgaaaat tcagatgaaa aagcggcttt tctattttag cataatataa
    16201 ttttattatt gcacagacac tttgatggta atattttgta tttttcaata tagttgtggg
    16261 tatattaata tagtcaacaa attcattctc atataagtta tataattctt catcacaaaa
    16321 caatgtaact aaatgaatct ccaaatcaaa cctgcgcaaa catttaatat attcgtttat
    16381 gtaagtgcct actccataac ttgatgctaa attcttttca tttataataa aaatatgttg
    16441 tttcatattc aaatatttaa cacaataata atcaagaaca tatacaaaaa aaaaaaaaaa
    16501 atcataaaga cactatttag cataatagtg tttgttcata aaaaatattt caaatataaa
    16561 taacctacaa taccttcata aagccccata tcatccattg acttaagatt tttgacagac
    16621 ttcttattta taaaatgact taattgagga ttaagattat tatttttctc acctttgaaa
    16681 taatcaagat aatatgatat ataaaatttg ctaatttcat ttagcttcgc ttgatctatc
    16741 tgtatgcatt tttcaaatat ttcagagaga aaaactttat caaatgaatg atgcctatta
    16801 tttttgatat gtataagtac ataatatatt ataccactta acccagtttc aaatgtatag
    16861 tcagttagtc gatatatatt ttgagtcatt atttgattat tcaattcaaa acataactca
    16921 gacgtattgt tacaatcaat aaattttcgt tgtgataaaa gctcgatacc aactcctatc
    16981 cctgaaagcc ctaatgctaa atttatagga gaatccatct ctatatcttc ccacaataaa
    17041 tctaataaaa aagaagcaaa cctcttgaaa gcatcatttt gagtaagatt tgcaaattcg
    17101 taaaggaaca aaacaatacc cattttccct ttataaagac tatttgattg gagatgtggt
    17161 gatttcaaaa atagctgttt gataatttcc gcatcctcta aataaaaaga attatccata
    17221 aataatatat attaaattaa agattaagtc ccccatgtaa caaattataa tttaaataga
    17281 tatagtgtta tttctcaaac tatgtatatt catttactta tagaatttaa ttgttaaaac
    17341 agctcgtttc ataaaatatt aatataacat ttcattaaaa caaatttaaa gaaacaatct
    17401 tatctactgc aaactaaatt tttaggctaa tacaatagac caatcaaatc ctacagaacc
    17461 tattaccatg ctcaagatac aaaacattta atttcaaact ttaataatcc tcatatgaat
    17521 aaacccaata aataaccaca agacttaatg tatacaaaga tagtattttc ctctgtataa
    17581 ttgatacctt aggaaaagtt ttaaaacata aatatggtgt ttatcctgaa cttgaccaat
    17641 tagcctgcaa catgaagaaa taccgcgggc cgaaccaatc aatggagaat acaagtgcat
    17701 attaataata tgtactcttg tcgtaaaatg gtacgcccac ttcaggaaaa catcctttac
    17761 atgtgagctt tcgggcaagt ccattccaac ttccgtacca ttaagcctca gtctccataa
    17821 caagcatttg aagaacagta ttcacagccc gtttactcca attgttccca tgctaatgga
    17881 attagggcat agcaactgga aaaagtaata tattgatgga atcaagatga actcagcagc
    17941 tgtcactata cctttgtccg acgaaaagta taaaaaaaca caaaaggtag caaaaaaaat
    18001 aatgtatacc tcctcatgtt aatgaaggcg ttttctatga caacaatatt tcgaaaaatt
    18061 gaccgacata ctttggaagc aaaaacagat gacattagct tagtaaacca cagtcaatct
    18121 gaacttcatc aaataaaaaa tcaatgagaa gcacttgccc aaactgcaag gatacgagaa
    18181 acacctagat acgatagatg aaagaaacag atatttcaaa actaacctta ttatgactta
    18241 catgcgtata aaaaaacagc ataaagaaga gacaacttaa aacagaaata taactgcgat
    18301 acctacaaaa aaacagttca cgccaaatta tagtccccgt cacaataccg gtgtcccctg
    18361 attaaacatt tacgatactt tactcagaaa ggcaggaaag ccaatacttt tagtgtaaat
    18421 tataataaaa cgtataaaaa ctctaacttg taattcccca actttacatc aaagtttcat
    18481 tttttaacca ttaggatatt gttttaacat aaaaaacaaa ctcatatgta ttaatcttgc
    18541 caacaaatat actatcaatt attttactgg cttaatcgta tatccttgtt tacccagcat
    18601 gtttaataca cctagtttac caggcaaatg accactccct acagtaaata gagttgattt
    18661 ttctttcatt attggcggca taagtttaac ccaattagca ttgcgtccat aatttaattc
    18721 ctcttcttcc tcaggaaaga aatcgcacgc attatccatt ttttctttca ttattttttc
    18781 tatcaaatct atatcttgat tgagataagc gattgtcatt ttttgataca tttgatctaa
    18841 taaatctaaa tgcatcaaag tacaaaatag ctgttctgcc tgacgctgta aactctgaga
    18901 attaaataaa acctttatct gaatatctat agtttccaat ccataaacct ttttaccttg
    18961 ttttcgagct tctgtttgaa tccatccatc aagttgttgc tggggattaa aattgttcat
    19021 agatttcatt gctaatataa cagctatctg tgatgtcaga gctgctggct ttaacttatt
    19081 catcattttt agttcaactc ccattaattg ttttattttt agagctatgc tatcatattg
    19141 tgcttcagtc atcaaagtct gtagcgtagt atcacctgga agcagagtag cttgttgtac
    19201 tttttgcata ttaataggga tcttcatgtc atccattacc aactcaccat atacttgttc
    19261 aacatcattc ataacctgtt taaaaccgat aatgctatct aaaatagaaa gaggtgataa
    19321 atgatgtgta ccaaacacat aggaaggttt agttagtcca ttaccagaaa tttgccataa
    19381 caattgagcg tttgctccaa gagagataca aacatatagt aataatataa aagtattttt
    19441 cataaaatga aattataaac taattcgaca ttaaataata atcgataaaa acatccaatt
    19501 ttttcacccc aataaggtgt ggagacatag catccttttt agagattatt atatgacaaa
    19561 aatagatatt tttcgtgaga taaggaaata ttaaatgtta aaagaaagcc tataagagta
    19621 caaatagttc tttgaagtat tgcaatttgg aagattgtca gcctcacaag attcattcac
    19681 atgcaacggg catatatatg catacgatgc tttgtaagat tacggtaaca tgtcttgtta
    19741 ttgcgagcat ggaagcagta ctgaaaatac ttgttcccac attatttctt ttgttaagtt
    19801 cttctttaga aatctattgc cgccattttt tctcggtaat cccctgcgtg tactcttcag
    19861 aaaaatatct tagcggtgta tttcaattaa tgcgtatctt ctacttccct tcttgctttt
    19921 ccaccggaat aacttccccg gttttcttat tcgtaacttg aagggcctta cctgtcattt
    19981 caaaatcaaa gcggccggtt ttaccctgca ctccggttgt tataaagtcc ataccatgct
    20041 ttttaacaaa agccctgttc gtttctccgt atacgccatc cgcatatagt gtttgcacac
    20101 tattgcccgt gacactttcg gtagcgatag tggcatcagt cacatatgaa ttgtcagtcg
    20161 ttgttgcagg ctctatctgt atgcttgtaa tgatagaaga cttgccttct tctgtcttct
    20221 cggtgatgtt ggcactgtag ccttttactt tttagtcatt cttcttgcgg tagtccgctt
    20281 cgaaatcatt agaattttgg acactgagag cactaattaa atgtttgtca cgtggaagca
    20341 gattgccttc atctgtatca tcgccttctt catctttctt ttttacgacc tcaaaacaca
    20401 cgacacgata gagaagggtg acgataaact cccgttcagc aattatctct ggaaataacc
    20461 agcctcgatg ttttgaagtt tggcagcgat ggtgtcctga acggaagtat agattacact
    20521 ctttgcgttc ttatgaagca gcacaagcac tttctctttc aactttgaag ggaaagggtt
    20581 ggttgtatct tcgttgatgc acttgagaaa tgtctcgtag acaagctgat aacgtgaata
    20641 ccaagcaatg ttactaccaa taagcctact gtccatacac ggacttttct gaaatgttga
    20701 acctgactgc ttgaagtgag ctcagttgag caaaacattt cgctaacaag tcaccttttt
    20761 ttttgcgcat acaaccaaac aatagcaaac catataatat gtgggactgc atcgcctatt
    20821 tcaaacaatc tcaatgcacg gcgaaatcac acttgttttc cagctcggca tcactgcatc
    20881 cgcattcggc tttgtatacg atcttgtcaa tctttgaggt gatcaaaata taaaacatgt
    20941 tgtgccaaag atctgggtct gagatatcat ggatgtgcac atttgcacat attcaacgac
    21001 ttgtcgttga atatatcaag ctggcgatta tggtctgctt ccttgaacat ttctatacat
    21061 ttttacaaca taaatgtacg aataagcttt caaacatgta atatctaatt aacattgaaa
    21121 taattaaaaa atcaataaga aataaaccac ccgttttttt tagcggactc atatattaga
    21181 agtcctagaa aacctgaagc atgaaagtcc ctaagccatg ctttttttct tcatcagcgc
    21241 tccccattta ataaatttca taaataaaag gtactttaga gagttactat atttatagta
    21301 ttttcacaaa acgccacatc aaggttcaaa tatccaacag attcctaatt aaatttagta
    21361 tttattcaaa ttcttatttc tttttcttac gttaagataa atcatcagta gcattttgcg
    21421 ctgcaacgca ctcagagtga gaaatgtcac ataatgggtt ttaaatcatt ggagttccaa
    21481 gggcatctca ttgattttat ttgcaaaaca atgagaaacg tcatcctcgt caacaaactg
    21541 cttgaaatag tctcttaagt ctttcgctac tgtatctact ctattgggac accaacataa
    21601 ttcaagcatt ctaatcttat ttattttttt aactcattta ctcttttaac cttccattat
    21661 cacagctaag aaaaaacaaa tctatcttta tctaatttta caattttgag aactttataa
    21721 atactaataa aagaagtcta gataaccaca tttacagtat gctcctttta ttttcagatt
    21781 acgatggaag aagtatataa aacccatcta cataattctc acgaatttat cgatctagta
    21841 tacaagaaaa atttgagaca caagctttaa ctcgtattat tctctaaatc tcaggctatc
    21901 aatattaagt tgccttaagt attacttcat aaaaagcttc tgcacaggaa actattcatt
    21961 catcatgaca atattgggaa aagcggaata ggaacaaaca tcatcggcag aaagacacta
    22021 agatagttgt gttgcaacaa gaaaaataca tgattgaaaa taagtagttt aagagccaca
    22081 acaaattcaa ccgtattttt atcactgctc ctctgaaagc tttaattttt acgttaaata
    22141 tttccgctgc tgcattggca ctacagttca caaagtagtc caacatcctc ttgtaatgat
    22201 tcttcacggg atttgtcaca gcggcaaagt gtgccgcatc tatatccctc gatttcatat
    22261 cactgagcaa gctggacgca tgccacattt tatccgtaca aaatgcgagt accagaggca
    22321 actagattcc ccagttgcag gtatatctgc ctgtgacaag atcttcccag cgacaacact
    22381 gcatgcacag gtacgtagcc ttcctagaaa tagagaatgt ttgaacctca atctctagaa
    22441 aaaacctttg gaatgtagat gtacataaaa agtttatggg gagtgtcagt tttggtttaa
    22501 tgccacaaaa taagcatttt aactaaaccc tctaaatttc acaactgaac cataacatat
    22561 attgttatag cagcaaaata aaccacggta aaaaaaagag ttccgtataa caccgaactc
    22621 ttttgaagta attaattatc taatcttttt ttgggggatc gatacaccct ccatatttag
    22681 tagaatctct ctctttttac ataataattt agcgtcacaa ctaaacaata atatgtaaaa
    22741 tatatcctcc gccagaaact taatttatga gcttctgact actcatgatt attagacata
    22801 acaaatttat caatttgtta acctgtacat aagcaataag acgctttaga ttcttgttga
    22861 caatacctcg tattacagcc atatgaagca caatcatcac atgctgatgc aataattgaa
    22921 taagtgtaaa gagatatcag agaaatcgtt gttataggag cactttttac ttcgttgttt
    22981 ccaccattta ctttatccat agcttcagac ggcatttcag caagcgtgat tttttttaat
    23041 tttagttttt tcatacttct aaaaatttta tcctcacttc aaaacgggca atagagttga
    23101 ggagaactct tattgtctgt attttatttg ctataaatat agcaacaaat aatacaaaaa
    23161 cacaatattt ttaatatttt ttaatataaa tctatattta acaataattg cattttctaa
    23221 caatcaaaca aaaggatatt atttacttaa ttatcaatat catatattga aaaaccagta
    23281 ccctataata cagcgggaca attaaccttt ctttagatta aaaaaaaaaa tatactcaaa
    23341 gcacatataa tttattagtc aacaacgtct aaggtttaaa cagattcaat tttaacgatg
    23401 tcaacttatc attttgttta catatatcat ttttacaaat attacaatgc gaattactta
    23461 aagcacataa agcaatacaa ttagaaactt acgaataata caaaacagaa attaacaata
    23521 attttagact tatgtatatc gattaataag ccattgtaat attatcaaga ttgtattata
    23581 tattataaat ttttggttga tagtaattaa gctatgcact acttgcgaat aaaatttcca
    23641 ataagttgca taagtattgt gatacaataa tctaaaaaag cagttcaatc ttctttgccg
    23701 aattgataat atacctaaag aatatgattc tgacaataga gtagattatg tctaatgagt
    23761 aacgtaaaat attcaatatt tataaaagcc tgtttaaatt ttatccaata gcatcttaat
    23821 agatgttagt tttaccattt cctctgccga atcacatatt aattcataat ttcggaaaaa
    23881 gccttctata gctgtcaaag catgaaacac ccataaaata aattttgtcc aaaaggatgt
    23941 aaattggtga atattaacta ccttagaagc atttaccaac agatagaata catgaataca
    24001 gtagctttta agcaagtgat tctccgaggt tgtggaatag atatccacaa ggacgtatga
    24061 taaccacgat aagtggcaaa gatctcaaaa ctggaacccg cagctagaaa accttcagta
    24121 gttctttgat gggattaaaa gaatagttat tatccaatgg cattacccat gtaacagtga
    24181 aagtaccggt gtttactgga aacctgccta taagattctt gaatgtctca gtatgaaagt
    24241 ctggattgtg aacacccacc atatcaaata tgtgcccggt cataagacgg ataagagaga
    24301 cagcgcatgg atctgtaagc agcttttgac aggtctgttg aaaccaagtt acatactaga
    24361 acgcgaacag catgaacttc gtgacctaac ccgttaccgc aacaagctaa tataacatat
    24421 aacctccgag aaaaaccgta tcgtgatatt ttggaagact gcaacatcaa actatccaac
    24481 accatgagtc atttggacag cgtagtggca acctagttaa taaacatact gataaagaaa
    24541 ggacacgtaa aaagaaacga cataacctgc atgtatcaca aaaacttgaa gtcgatccga
    24601 aactacttta tcaggcgtgt gaaagtttta taaaaccgca tcatgcttat atattgcaaa
    24661 ccatccgaaa ggatattgaa cagacagaag ctatcattgt agacctgaca tcccgcatta
    24721 aggtcgttct ttccccttat gagaatgtgc ttaaactttt atcccccgga cttagcagaa
    24781 aaacagtaga agacctgata gcagaaatag gtgtcgatat ggaagccttc cctacggaaa
    24841 aagcatctga cttagtgggg tagtatgtgt ccggggaata atgaaatcgc aggtaaaaaa
    24901 gtaaaacaat cacacataaa aacgaacagt tgaaagccat cattacagag actgcctggg
    24961 cagtaatccg taccaagaat accttttaca gtgcacgcca tcaccggttg gcagtccaca
    25021 gggggtaaga aaagggcttt gatagtagta gggcactcga tactgaaatc ggcatgacat
    25081 atacttaata acacctgtga gtacaaggaa ctcgaggcgg aatatctcac cccaaggata
    25141 gaacagaaaa gaaaagaaaa aaatatttaa agaaggaact ggaagtactc tgctataaag
    25201 taaaaatcag ccgcgatgat atttcaatcc cccgaaggca agtcagaagc atacaaaagg
    25261 gtaactttca ctggcttgct gtcgtaaaaa acagccagag gtcgtacata aaactaatct
    25321 caacagctaa gcgatcaaag ctgcgagtcc tttaacgtgt gtatgaaact tttctttctt
    25381 agctgttgta aaacaacaaa atgccgaaag ataatagcca agcgcatttg tatctttctt
    25441 gtgttttgtc cagactgtac gaatcaattt attaatggtt agaaactgct ctctttacaa
    25501 tggagagtac aatttattta cgcatgaaaa ggttctttct acaatccact ttttacctta
    25561 tcatcattaa cgataacttc tatgatatct ccaaaaacat ctttgatctt ctgggttatt
    25621 tctccacagt atccggcgtc agccaatatt actttgatat tttccctcag ataccttacc
    25681 agtaaataaa caacttacta ttatgtacac aagcaatcgt caccatgaca gcaagtagaa
    25741 agccattttt atccaccacc acatgacact tgacaccttt tactttcttg ttcccatcaa
    25801 tgccgccgtt aagggaacgg tgatttccca aacacacacg ttgactatcc ataataccaa
    25861 ggctcacctc tgctttttac cccatctata aatgtacttt ttctcgtaag ttgttcaata
    25921 ataattcaaa ttcacctaaa gaggagtatc tgcaataata gtagtaagcc aactcccaag
    25981 gagcgaaatc ggagggaagc atacgccact gacaaccgat tttcactaca tagaaaatag
    26041 cattccacat ttcacgtaaa tcatatttcc gtttcctttc ttgcaaattc aagattttct
    26101 tgataacttg ccactgtgtt tcttctaacc atgttgaata catgattatt ttaagcgtgg
    26161 taactaaaaa ataatcattt tcaaggaaag aaaaaaacac tctttttatt tcaaaatgga
    26221 aaatttaaac aggctctaat atgaaaacga ttttattaaa ttgccttcct cccgcaatgg
    26281 aaaattgtgc atcacctgca ccctctgttc ttaagcatac attacaaaat aatggattta
    26341 aaacagatgt tttatactgg aatttaaaac ttaactcttt tctacgaaat tatctcaact
    26401 ttggagatta catacataga gatgacatct ataaattatt acctttttat attcatattg
    26461 caattgaaga aaatgatcaa gaactcttga acaaattagc atattctgtc ctttatcata
    26521 agcctgaaat tcactcaaaa gggatagcct atttatattc atatttttac gaacaagata
    26581 aaaggttaat tcatattatc aaagaatgtc tgcaatccat aaacatgaaa gaactactat
    26641 ttgttggttt ttctgcaaag ttctcacaat ggattgtggc aactattata gctaaagaga
    26701 taaagaaaat atataaaaaa ctacctataa tcataggtgg gtttggaaca ccccaagaag
    26761 cccaaactat tcttaaaaac tttaattgtt ttgacttgtc atcttggggg gaaggtgaaa
    26821 actcaacact attactggct caacatggtt tttctgaagg agtacttaac aaaattccgc
    26881 atatttgtta tcgaaattgt aatacaatca cgtctaacaa agcgattaat acttacataa
    26941 atttaaacaa tgtcagtttt gatatgtcag attatttttc acaaataaaa cttcataaat
    27001 tacctcttac tttaatgatt ccaattgaag caagtagagg gtgcaattgg ggaaggtgta
    27061 aattttgctt tttaaacaaa ggatataaat ttagaactaa atccgtaaaa agcgttaaaa
    27121 acgaaatatt aaattacatt gaaaaattta attgcacatc tatatttttt cttgataata
    27181 atatcgtagc taacgataat ataagattcg atacgctac
//
