LOCUS       c00042_gnlPro..        15679 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IEFIKGMA_42.
ACCESSION   c00042_gnlPro..
VERSION     c00042_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:58:14
            Original ID  :: gnl|Prokka|IEFIKGMA_42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15679
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..135)
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MSVYKSKFQPVMERWSLVLKIVLLTTGLMFLLRTFMLQSLQDQIA
                     "
     protocluster    1..15679
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[915:5679]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      916..5679
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15679
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15679
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(135..926)
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENFVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKNCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             complement(916..1962)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.8e-10, bitscore:
                     32.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLNFISPNTLSLLTTYYCTAACKNCCFECNQERRGRMSFKQME
                     TYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAHKKGLITRVVTNGYWAVSYEKA
                     LGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRAAAKVDLPCLVNIETNPSSQFS
                     EEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRDTNYNELIKHRYVQRPIISHGC
                     NSLFESIPIDPEGNVYACCGLACRKAKFLKIGNMNTAGINKIYTRQFDDFLKVWAYVDG
                     PKFILNKIAMETGKNIEVNADMHNCEACLLLLNDPSKIEYIKNNISRYISEVVLKYNIK
                     QKKANYEK"
     CDS             complement(2518..2631)
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MLNSIKIPIYGEKLDSSYYFQIYFSNIFLRNNLQVKK"
     CDS             2721..4949
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_5"
                     /sec_met_domain="Gly_radical (E-value: 2.6e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1164.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVETDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4954..5679
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_6"
                     /sec_met_domain="Radical_SAM (E-value: 3.5e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(5912..7171)
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKQPEAVTEEKRAEPQQEATAAIEK
                     KESVTAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGVVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(7226..7774)
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             7962..8714
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(8819..9817)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg42_10"
                     /sec_met_domain="LysR_substrate (E-value: 1.3e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.4e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             9887..10360
                     /locus_tag="ctg42_11"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(10464..11462)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_12"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.6e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(11517..12785)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_13"
                     /sec_met_domain="MFS_1 (E-value: 4.6e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(13035..14048)
                     /locus_tag="ctg42_14"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(14071..15207)
                     /locus_tag="ctg42_15"
                     /transl_table=11
                     /translation="MKRITIKQCLFACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 tgcgatttga tcctgcaaag attgtagcat aaaagttctt aatagaaaca taaggccagt
       61 agttaataag acaatcttta ataccagaga ccaacgctcc attaccggct gaaattttga
      121 tttatatacg ctcattatat tgctaatgtc ttctgtatta tttcaataag ttctttatcc
      181 gtatatcgtt ccataacctc aggacgtttt tcttttacta acttaaccaa atcttgaaca
      241 tagtgatttt tgtactcatc tgctaactca tatacacttc cgtcctgtgt ttcaacgtcc
      301 caaacctgca atgccatttc actgttaatt gttctggaag cacatactac gggaccacca
      361 agtgctgcat aatcaattcc tgccccaaca tatgcaacac ctaacaaaat ccattcaccg
      421 atccaaaaga atcccatttg cacatctaca cagtttttac ttcttgttat tgcagtatgg
      481 ttcaataatt taatattgga agaattggca tttttaaaaa tatcatactt ttcacataat
      541 tctacaaatc ttctaatatc tctctttatt acagcctctc gaaattccgg cttacaaatt
      601 gctaataaaa aacgtacagt accgtcatca gtatctatag agctttttat tcccaaagac
      661 cgggcatatt ccaaaggggc attcaaaaag gcttccgctg catttgtatc atttaaaata
      721 ttatgtgata ataaactcat atcgtgaata tacacctgtt cctcctgtga taactttttc
      781 atagaaatag cagtagtttc atcatctaca aaattttctt ctgacgcaat agctaaatta
      841 ggaaaatcat ttgaattatc acatgaagaa aatgaagtag cagctattgc tgccccaaca
      901 cctaaagtta gaattttact tttcatagtt cgctttcttt tgtttaatat tatactttaa
      961 tacaacctca gatatatatc tggatatatt gtttttaata tactctattt tagagggatc
     1021 attcaacagc aatagacagg cttcacaatt atgcatatca gcattaacct caatattttt
     1081 cccggtttcc attgctattt tatttaatat aaatttcggc ccatcaacat aagcccatac
     1141 ttttaaaaaa tcatcaaatt gtcttgtata tattttattt ataccggcag tattcatatt
     1201 tccaattttt aaaaacttag cttttctaca agccagtcca caacaagcat acacattccc
     1261 ttccggatca ataggaatac tctcaaatag actgttgcac ccatgggata ttataggtct
     1321 ctgcacatat ctatgtttta ttaattcatt ataatttgta tcacgtttaa ttttatcctc
     1381 catatcaaat ggaatccata taccagaaga aaagataact ttattatccc gtatatactc
     1441 ttttaactct tcatgatttt tgaaatcttc ctcagaaaac tgtgaacttg gattcgtttc
     1501 tatattcacc aaacaaggca aatccacttt agctgctgct cttatagcat ttacgatatt
     1561 atcaaagggc acccattttt gatgatcatc ccccgtgctt aaatttaatt catttaaccc
     1621 caactccttt agtaacacca aaattccaag agccttttca taactaacag cccaataccc
     1681 attagtaaca acccttgtta taagcccctt tttatgtgca taataaatag cttgatataa
     1741 atcatctttt aaggaaaaac attctccacc actaaagaca accagcctaa tcgtagggaa
     1801 agcttttaca cattccgata tataggtttc catttgttta aatgacattc tccccctacg
     1861 ttcttggtta cactcaaaac aacaattctt acacgctgcc gtacaataat aagttgtcaa
     1921 caatgataag gtattaggtg atataaaatt cagtaattcc atggctaatt attcacttaa
     1981 gagtttaaac tctttcaaaa tattacttat atggcaaata tactttattt ttgttacagc
     2041 caaacggtta aacacgaaat tttaatctaa ttatacaatt ttatcaatgt gaataacaac
     2101 ttacaaaatt ataattttat tagattagaa aggaagtagc attcatagcc ctcacattct
     2161 acatttgtag aaacagattc aatcaaaaca aaaaatatat aattattagc cctctataga
     2221 cacactgcat aagcaggaaa tttagaatag cctccagttg gaataattaa atacggaaca
     2281 gcaagaaaca aatcttaaat aatacaaaac acccaatttt acttttcagg gtgtaaaatt
     2341 gggtgttatt cttgtaaaca actgattatc aatgtttatt gcggagagac agggattcga
     2401 accccgggta cctcgcagta caacggtttt caagaccgcc gcaatcgacc actctgccac
     2461 ctctccagaa ctacggttaa gtagtgcttt tctcttaaag cgctgcaaag gtacgaatca
     2521 ttttttaact tgcaaattat tccgcaaaaa aatattagaa aagtatattt ggaagtaata
     2581 actgctatct agcttctccc cataaatagg tatttttatg ctattcaaca taaaatagga
     2641 cccttttata tacctaaacc gaaaaaaggt tgtaaatttg cgcgctctaa aggataacta
     2701 accactaact gattaatttt atggaactga ataagacctt taaagatgga ctttggagta
     2761 aagaaatcaa tgtaagggat ttcgttagta acaacatcac tccttatgaa ggggatgctt
     2821 ctttcctgca aggacctacc gaacgcacca aagctgtctg gaatcactgt ctcaaagctc
     2881 tcgaagaaga gagaaacaat aatggtattc gtgcactcga ctacacaact gtatctacta
     2941 taacctctca ccctgccggc tacatcgata aagagaacga actgatcgtc ggactacaga
     3001 ccgatcaggt gttaaaacgt gccatcaaac cgtttggcgg aatcaatgtg gttatgaaag
     3061 cttgccgtga aaacggagtg gaagtagatg acagagttaa ggatatcttc actcactatc
     3121 gcaagactca caatgatggg gtattcgatg tgtataccga agaaattcgt tcgttccgtt
     3181 cattgggatt ccttaccgga cttcccgaca actatgcacg cggacgtatc atcggtgatt
     3241 atcgccgcct ggctctctat ggtcttgacc gtctgataga agctaaaaaa gaagatctgc
     3301 ataatctgac aggtcctatg actgaagccc gcattcgtct tcgcgaagaa gtagccgagc
     3361 aaatcaaggc cctgaaagag attaaagtat tgggcgaata ttatggtttg gatctgagcc
     3421 gaccggcata taccgcacag gaagctgtac aatgggtgta tatggcttat ctggctgccg
     3481 taaaagagca ggatggtgct gccatgtcac tgggtaatgt atcttcattc ctcgacatct
     3541 atcttgaata tgaattaagc cagggtacga taaccgaaac attcgctcag gaactgatcg
     3601 accaattcgt tatcaaactc cgtatggtac gccacttgcg tatgcagtcg tacaacgata
     3661 tttttgcggg tgatcccaca tgggtgaccg aatctatcgg tggacgtttc aatgatggac
     3721 gtaccaaagt tactaaaact tctttccgct tcttgcagac actttataac ttaggcccgt
     3781 caccggaacc taacatgact gtactatgga gccctgagtt gcccgaaggt ttcaaagcat
     3841 tctgtgcaca agtatctatc gacacttctt ccgtacaata cgaaaacgac gacctgatgc
     3901 gtgaagtccg tcaatcggat gactacggaa tcgcttgttg tgtttcatat caggaaatcg
     3961 gaaagcagat tcagttcttc ggcgcacgtg ccaaccttgc caaagccctg ctactggcta
     4021 tcaacggagg acgttgcgaa aatacaggta cagttatggt aaaagacatc cctgtattga
     4081 ccggtgaaac actgaagttc gaagaagtaa tggccaacta taagaaagta ttgatacaaa
     4141 ttgcacgtgt atacaacgaa gcaatgaata tcatacatta catgcacgat aagtattact
     4201 acgaaaaggc acagatggct ttcgtggaaa ctgatccccg cattaacctc gcttatggtg
     4261 tagccggact ttcaatcgcc atcgattcac tgtccgccat caaatatgca catgtgaaag
     4321 cccgtcgcaa cgacatcgga ctgacggagg gattcgatat cgaaggtgct ttcccttgtt
     4381 tcggtaatga cgatgaccgt gtagaccacc tgggtgtaga cctggtatat ttctttagcg
     4441 aagaattaaa gaaactcccc gtatataaga atgcccgtcc taccctctcg ctgctgacta
     4501 tcacttcgaa cgtaatgtat ggcaagaaga ccggtgccac tcctgacgga cgcgccaaag
     4561 gcattgcctt tgctcccggt gccaacccca tgcacggacg tgataaaaat ggtgcaatcg
     4621 cctcactgag ttctgtagcc aagttgcgtt atcgcgactc acaggatggt atcagcaata
     4681 cattctcgat cgttcccaaa tcattgggag caacacaaga ggaccgtatc gacaatctgg
     4741 tgaccatgat ggacggatat tttacaaaag gcgcacacca cctgaacgta aacgtgctga
     4801 accgggaaat gttgcaggat gcgatggaac atcccgaaaa gtatccgcaa ctgactatcc
     4861 gtgtctcagg atatgccgtt aatttcgtga aattgagccg cgaacatcag ttggaagtaa
     4921 tcagccgcag tttccacgaa agaatgtaat tgaatgataa acgtacactc atacgagtca
     4981 atgggaacat tcgacgggcc gggtctccgg ctcgtcgttt tccttcaagg gtgtaacttc
     5041 cgttgcctct attgtgccaa tccggacaca attgaagcca aaggagggac agcaaccgat
     5101 cctgaggaaa tagttcgcat ggccgtcagt cagaaagctt tcttcggtaa aaagggaggt
     5161 atcacctttt ccggcggaga gcctactttt caagcaaaat cgcttatccc actttttaaa
     5221 agactaaagg aagcaggaat ccatatttgc cttgatacca atggcgggct atggaacaat
     5281 gatgtagagg aactattgga attgactgat ctggttttat tagatatcaa agaatttaat
     5341 ccggaacatc atcagtcttt aaccggaaga agcaacgagc agaccctgaa aaccgcagcc
     5401 tggcttgaaa ccaatcataa accattctgg ttgcgatacg tattagtgcc cggctacagt
     5461 gacttcgaag acgatatccg gcagctggga gagcatcttg gaacgtacca gatgattcag
     5521 cgtgtagaaa tattgcctta ccacaccttg ggcgttcaca aatatgaagc aatgaacaaa
     5581 gaatatatgc tgaaaggagt gaaagagaat actccggagc agatagaaaa ggctgagaaa
     5641 ctattcaggc aatacttccg gaccgtacaa gtgaattgac ttatataagt gtcgaaattc
     5701 gtattcgcca cagattacac gaatttacac agataaagat tcattggcaa tcaacagatt
     5761 aagttcattc tgcggtgaat tatgacgact gcacttattt ataattttgt aagtcacgat
     5821 ataaaagtct ccctgttctt gccttaattc attacaatac aaggcaagaa cagggagata
     5881 atgtaaccgg catatttttt gccaccctac tttaataagt gaatcgcaat cctgcctgca
     5941 agttaaagtt acaaggcctt tcttttcgga tggtttgtac tttggagcca tcatcaaaga
     6001 aatacgaaac tcccggttcc acatataggc cgacatgatc tgtcgcattg aattgcgctc
     6061 ccacgacacc ggctacagaa aattgcaaag gcttcacatt caccttatca tccgccaact
     6121 ttccataaac acacttttca accattcctc cggcagatac atagagtgta aaatatttct
     6181 tttccagaaa attccagttt ccacgtacag gaatacctat ataatgcaat ttctgactct
     6241 gcatcttggt atccccctgc cgtttgatgt cagaagacaa caacgtataa gtcaatcccg
     6301 tctctacaga gaaacctttg ggaagagact tacgtacaga cagtccgaag ctaaccggct
     6361 gatgatgttc ataatccacc acggcagttg tattggactt caggtaaggg actccttctt
     6421 caaatataac ttcctgatcg gcaggaatac tcacagctcc attcatgatc gtcatcaagt
     6481 cgaccctgtt agtcatcgga cggggcgcaa aattttcgga accatttgtc ggaagtccac
     6541 ctccattacc gatacccact cccatcgacc atttaccacc acgtttagca gaagagtctc
     6601 cgataggcaa ctgatacttg tctttaccgg acggtcgccg cgcttctttc ctctttggag
     6661 gctgcgctgt cacactttct tttttctcga ttgccgcagt tgcttcctgt tgcggctcag
     6721 ctctcttttc ctccgtcact gcctccggtt gcttctctgc cagggaggat acctccggaa
     6781 caatcaccgg atcagtattc tttgccaaat agcccgaaac agggttaata ctcgtcgttc
     6841 ctaccggctt aacgggttcg gatacagcta cctgtacatc cggcaaggca ggttccggca
     6901 atacatccgg gttgacagcc agtgaaggag ccgttgcata acggatttca tcagctaccg
     6961 gactattcag aaaatacaaa ctgacagcag tcgttaccac caataccaca gctgccgcag
     7021 caaccgccca ccggcgatac ggatatattc gtttttcggt tacaggcatc agttcccttt
     7081 ccagtcgttc ccaaccggaa gcaggcatcg gctccgaata atcttcgagc ttatccttga
     7141 atgctttaat ccatttttcg tcttctttca tcattctatt tcatttttga aatccaaggt
     7201 tcacctcagt atctgtaaat acatgtcaac cattggtcac caaccattct ttcactttct
     7261 ttgccaatac actttttgcg cgaaaaagct gtgaggcaga agatttttca ttaatcccca
     7321 acatctgtgc gatttccttg tgcgacttat cttcaaaggt gtataaattg aatacggtac
     7381 gatatccggc ggggagttca ttaataaatt gcatcagcac tttctgtggt attgcttcaa
     7441 cagccgaagc atccggttct tcatacgttt cgggaacttc atccagtgcc gtggtctggt
     7501 tcatcacgtc gttctttctt aagaactgta aagccgtatt caccattaca cgctccatcc
     7561 atgctctcag agagccttca ccccgccagg taaacttgtc gaaggagtcg aaaatcttca
     7621 ggaaaccgtc gtgtaccaag tcttgtgcca tgtccctgtc tccggcataa cgaagacaga
     7681 caccaagcat gcgccctgcg tactgctcat aaagttcttt gcgggcacga ttatctccct
     7741 gcctgcaacg ttccgacagc tctaattcat tcattctcct aaacacgtgt ttaccttata
     7801 aatgcagcaa agatagaaat actgcacaga gagaacaact cttttatcac ttttgtttct
     7861 ttaacatttt aggatgcaat atttcatcac ttcctgcatt ttctcaatac aataaagaat
     7921 aaatctcaat ggataaatag gataaaacca acaagaaact tatgaagaaa tttaatttaa
     7981 taacttttgc cgtcatcctg atgttattgc ccattttaca gtcatgtctg gacgatgcca
     8041 acaacgacga gtgggtcact tgtcctccgg gtggaatatt ggccatcggc acaatgaaga
     8101 ttcccaatgc ggacactcca agggactttt tcattgcgtt ggacaatgga gacaatgtac
     8161 ttccggcaga tacggccgat atacgcaaca ggaaatacac tgttgcagaa ggtcaaagag
     8221 tcttcgttgg ctatctgcag atgggagaag agaaacccgg atatgagaac ggtaaaatat
     8281 tcacgataga agatatattg acgaaagaga tcatcccact gacggaagct acagcagaca
     8341 gcattggaga cgaccgtatc aacgtcacag cgcatgcact tacgaaagat tatctgacca
     8401 tcgaatatca atatctgggc agcatgaatg aaaataaaaa acacatgctg aacttggtac
     8461 aaaacgaaat aacaggtccc ataaaagatg acggatatat ctatctggag ttccggcata
     8521 atgcctttaa tgactccccc aatcaattgg gttcgagcct tgtttctttc aagctggata
     8581 gtatagccga gcaattggcg acagccaaag gaataaaact ccgtgtgaac accatttatg
     8641 acaatataca gtatgtcaca atagatatca acgaagacaa aaacttaaaa ataaaatcat
     8701 ttcattctca ataaaacaac aagaaacacc tacacaatca ggcaaaacga gtaataattc
     8761 tgatacataa aagaaataag gcggcgatgt ttgtgaaaat atcgccgtcg tttttatatt
     8821 ataccagaca ctgaacggcc tgcagggtaa gcatctcctt gggaaccgcc gcctgaatct
     8881 cctctttcaa aacctgcagc agactggtgc ggatgaagtc tttccgggtc accaggacaa
     8941 tctgacgggt aggccgcggg atagcaaacg gacggaccag ttctttctgc tcttcgctca
     9001 attgcatcac tgccagttcg ggaataaacg taatcccctt accactctcc accatatgca
     9061 taaaggtttc catactaccc agccgatacg ccatttggct gatcttaacc gcttccatct
     9121 gacaaaaacg aaccaactga tcgcggaagc aatgcccttc gtcaagaagc caaagccgtt
     9181 cccctgtcac atcggacgta cgaatcacat cgtgcttgaa caacggttcc ttctttgaga
     9241 catagcccag gaattgctcg tagaataagg tctcttccgt taatgcggca tcatccagca
     9301 tgctggcaat gatagcagca tccgcttcac cggtcagcag agccttgcga atgtcgggcg
     9361 tcttcatctc catcacccgt atatcaagat ccgggtattt ctccatcagt tgcggaaaga
     9421 aacggggcag aagataaggt gcaatcgtcg gtaacactgc caatcggaat gtacccgaca
     9481 gggagtgctg ttcttcgctg atgatctcct tgacacagat aacttccgaa agaatcttac
     9541 gggcctgttc cagcactttc ttaccaatgg cagtagggca aaccggtgtc atgctacggt
     9601 cgaacagttt cacccccaat tcgtcttcca gcttctggat cattgcactc aaagtaggtt
     9661 gcgtcacccg gcaatactcg gcagctttag caaaatgccg gaactggtcg acagccagaa
     9721 tatattccaa ttgttgtata gtcatcgttc tctgatttat taaagatata gaatctatca
     9781 atgcaaagat agaaattttc agtttgacac gaatcatttt gtgccgtatc tttgttccag
     9841 ataaaaagaa gaaatatagt attaactcaa aaaaaacaat atcattatga agactttaaa
     9901 ttatacacat ttggaagaaa aaggagctaa caccatcgta ctgtcattac agcaactgct
     9961 tgccgatttt cagattcatt atgcaaacct gagaggattt cactggaaca tcaaaggaca
    10021 cggtttcttc gtactgcaca gcaagtttga agatttatat aacggagccg ccgaaaaggt
    10081 ggacgaaata gccgaacgta tactgatgct gggaggaact cccgccaata aatacagtga
    10141 ctatctgaag atggcgcaga tcaaggaagt ggacggagtg aataaggccg acgacgctct
    10201 gaatcatatt ctcgaaactt acgggcatct gattgcggaa gaacgtaaaa tcctgtctct
    10261 cgcctcttca cacaacgacg aagtaacagt ggccatgatg agcgactacc tgaaagaaca
    10321 ggaaaagatg gtttggatgc tgactgcata caacggataa cagccgaaag ggtgtagcca
    10381 tctgaccgaa aaggtgtagc catacaagca aaagggtgta gccatcccgg cgggatagct
    10441 acaccctttc tgttttattc gattcagatg atacttgtac gtttggtaaa ttcaataatt
    10501 tccggaatgt atccgaatgc gagcccggtc actgtatccg cacacccata atagatggca
    10561 atccgtccgg tctccgaatc atgaagcgct gcgcatggga aacagacatt aggcacatca
    10621 cccatacatt cgtaatcctt ctgaggtgaa atcagataag gccccgaacg gaattttact
    10681 ttccagggct gatcgatgtc aagcagtgcc gaaccaaaac tatacacaaa accgttgcag
    10741 gaagccaata caccatgata gatcagtaac cagccttccg aggtttcaat tgggataggc
    10801 cctgcaccga tcttggtaca ctgccaggca ctgtcttcga acggagccgg cgacataaca
    10861 tgacgatgac gtccccagaa ctccatatcg ggagactcgc tatagaaaat atctccaaaa
    10921 ggagtatgcc cattatcact cgggcggctc aacatcgcaa aacgaccgtt tatcttacga
    10981 gggaacaaga ctccattccg attgaaggga ataaaggcat tctccaactg gtgaaaagta
    11041 acaaaatcat aggtgtaggc cacaccgata gtaggaccat gatagccatt acaccaggtc
    11101 acatagtagc ggtcttcgat aaagcaaacc cgtggatcat atccatagac ccaggttcca
    11161 acctcagcgt catcacattg aaactttaac ggttcttcgt tgatatccca atgaacagca
    11221 tccttgctga atcccacatg caaacgcatg cgacgattag tatcatcaca acggaacacc
    11281 cctgcatagc catccttaaa cggaactacg gcactgttga atatactgtt tgaagtaggg
    11341 agcaagtcgc gcggaataat cggattggcc gaacaacgcc acactacatc tttacatcct
    11401 gccggacgtt cttcccaagg catagccggc aaagcagcac ctgcaatttt aatttcttcc
    11461 atgattcgat taaattaata ttatgtatat atcttgttta tattgaaaat ctctttttat
    11521 ttcttctttc cgtccggata tgtgaaaggt accagccaag tcacgataaa agccggtatg
    11581 gtagcgataa gtacccagat aaagaaatcg cgataaccca gccaatcgct caggtatccg
    11641 ctcatcattc cgggaagcat cacccccaga ttcataatac cggtagcaaa agcataatgt
    11701 gccatctgat gtttgccggg agccacttgc tgcatcataa agagcatcaa tccgacaaaa
    11761 ccaaacccgt aacccaagta ttcagacaca atggccatac caataatcca tagatcggaa
    11821 ggctggtaaa gggctaacag gaaatatacc aagaacggaa tattaaaagc gcaacataaa
    11881 gaaaacaaag tcttccgaag tccgaaagcc gaaatgtaat aaccggccaa aagcgaaccg
    11941 agaataaaag ctcccgctcc gaacgtacca tataccaagc cgatatcctg agtgctgagt
    12001 cccaatccac catccgcaac cgacgctttc aggaacaacg gtacaatctt gatggcatat
    12061 ccttcggcaa accggtacaa aatgataaag acaatgtaga aagcaatatg ttttttttgg
    12121 aaaaaagagc ggatgacttc ccaaagcata ttcaatgcgt cactcatcgt attcacttca
    12181 ccggaagcgc ctcctcccga aggcaaaatc cggatgtggt aaagaccgat cagaatcata
    12241 atacccgcac acatcaacat gacaatcatc caggcatgta ccactccaaa ttcatccttc
    12301 agcatacctg ccagccaaac caagcctccg ttggcaagta tcttggccag attataaaaa
    12361 gctccctgcc aaccgatata cttggcttgc tgggtagcag tcagttcagt caggtatact
    12421 ccgtcacccg caatgtcatg agtcgcacca ctgagagcaa tgatccccat cagagcgatg
    12481 gcataacgaa aaaagtcggg cagcggcagc gaaagtgcta ccaatgcaaa tgccagtccg
    12541 gtaatgattt ccgtagcgac aacaaagtat tttttcgttt taaacatttc cagaaacgga
    12601 ctccataaag gcttcaatgt ccagggaagc ataataagag aagtccagaa agcaatctgt
    12661 gcattcgaca cttccatatc ggaaaacata aggacagaaa ccatcgaaag ggccacaaac
    12721 ggcaatccca tagcaaagta aacagtaggc acccaacata cagggcttat cggcttttta
    12781 ttcatcagtt agttttttat aataattcca tcggttaaca attccagtaa gcaaagatag
    12841 gggatattaa aaacataacc caagattacg acaagaagtt gctttcatta tttaataata
    12901 caactcaccc gggaaaacta ctaacctcta tcaccctttt tttattaaac tttatcaata
    12961 caatacacgc aaagaagcac cgaagacttt catccccgat gcctctcgcc cccttatcta
    13021 caatctaaac acctctattg cttcacatat aaatttatct cagcaaaccc ggtataatta
    13081 tccggagtca gacagtttat tctgaattcc tttacattcg ggataggtgg ttcgatggcc
    13141 gcatattgcg gatcagcccc tttaaaattt ctgaaagtca agactctcgg gtaagtaacc
    13201 cactcggttt caccctcttt ccgaacctta atctcagcac ttctcaggtt ataacccgat
    13261 ccgtaggcac tctgtttagt gaccgaaaat ccggttaagg taacaggccg gtccagtacc
    13321 gtattccacc aacactctcc ggcattagcc actccccatg taaaccaagt agtatttatc
    13381 tcaccgtcaa tagccagatg tgcaccatat ttggcatcat catcggcata aacattactg
    13441 caacttacac tccacgcact tcgatctaca gcggaccaat tcccgggttt cgtataactg
    13501 gtataaagca cgctggtata aatccggata taaaccgtct tcatagatgt actgacagcc
    13561 tgttcgtcca tgcccgtaac tcctttaagc gtcacgggaa gcacatatcc gtcaggatta
    13621 gtcaactttt ctatattctt caaaacgacc tgaaaagatg aatcggccac tgtctgtccc
    13681 gtttttaaga caacttcact tgtttcaatg gtataattat cttggggcaa caacttacat
    13741 ttcgtcttat tggcagaatt gtaagtatcc actttcagcg tatctactcc caaagcggca
    13801 gtgacatccc gcgtaaccgg ctgtacggca cacaattgta tttcaaaatc agaacggtca
    13861 gcagtagagg aattgctcac acaatccacc actaccgcag cacccatttc ggcccccggt
    13921 gcaactcccg ttctgatata tatcttttga tatttgtcca tttcatcatc atcgttgctg
    13981 cacgaagcca acgatacaaa gcctgttatc aggcagatta aggtcacaaa attcaaatgt
    14041 ctattcatat cttatcttct ttttacatag ttattgctta tcaaaacgaa catgctcttt
    14101 ccagacaaga gttcctcctg ccaccaaatc gtatccgtgt ccggtacagt cggcaaaggc
    14161 atttccctta ccttcatcca ttttccaata gcctatcagg ttcggatcgg cgggtttcac
    14221 ggcaaaatac atgttggact gaatttgcgt ctggctgatt gcgctcttcc aaagacgcac
    14281 ctgggccatc tgacaattgt tgcggaagta actaccgctc gaaaccatgt tcatcttgtc
    14341 gaatcttacc gggccaccct ttgtctgcag agtcacgtcg agcactccgt tgatataaat
    14401 cgacaataac ccggaagaat tataaacgaa ggccagatga taccacttat tcttctcaaa
    14461 caaagtcacc gtattgacct gacttccaag tgtcttcacc tgtaatgaat tataagggat
    14521 catagcgtca ccgaaacgga tataaacctc gtggtcgctg ctgcccgaat taaatatagc
    14581 ctgattatta atatcgaatc cgtccatctg tacccaagcc tcgagtgacc attcattggt
    14641 tgtcactccc cacaattcgt ccttggcggg cttcacggca ttggtcgtat tcataaacgg
    14701 tacagactgt atcagcggct tatccagcaa aatgataaac ttcgacgaaa gcccgattgt
    14761 agacaccggt ccctgaattt ctgtgagaga taccggaata gcatacaatt ctccgttctc
    14821 gtttgaataa ggtttcactc taaactcact ggggattgcg ctaacatcgc ctgccgctat
    14881 ctttatctct ttgtcataag taaaatactg ctcgggaagg acttcgtacg aagtttcatt
    14941 agcttcattg tactctttaa gaatagaagg atctaccgtc aggacagcag tcacattttc
    15001 ggttacaggc tgtcccacac gtacggtcag agtagttgtt gttacatttt caggatcaac
    15061 ggtaaccttt gccgaaccat tctcggatgc ttcattcaaa taaatcgcat tgtcgataac
    15121 ctggtaatcg gcatcgttgc atcctgccag gatcatcggc agaacgaaac aggcaaacaa
    15181 acattgtttt attgttattc ttttcataat caaattcttt aaagtcattt tacagcagga
    15241 ttcattattc tgattgcttc acgcaggtac ttatattcga tgtcgcccgg atagtcatat
    15301 tccatgtgat aggtgcctac tccacccttc cgtacctgtt ttccgtcaat agtcggagtc
    15361 cagcgtgcca tgccggcaag tgctctcatt ttgtttccgt aacgatctac ataatcacct
    15421 cctcctgtcg gagcataaga ttcgaaattc tccgtaacga tgtacatatt agccactttc
    15481 tccggaggaa gtattccttt aaagttggca atcgtaccag ccagacgtct gtcaagatta
    15541 gcgtcggaat tacccgcaag gttagagtat gcctgcacaa tgaaatagtc aaagtaaggc
    15601 ccggtttccg gatgaatact ttgaggctcg ccatcaatca caagtaaccg tcccgtaccc
    15661 gatttaggtc cgattcttt
//
