LOCUS       c00038_gnlPro..        16575 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBCKPFCG_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:34:32
            Original ID  :: gnl|Prokka|MBCKPFCG_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16575
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16575
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3177:6735](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3178..6735
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16575
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16575
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(605..1759)
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1939..3144
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3178..6735
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6860..7048
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7059..7919)
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7947..8777)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8774..10000)
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10473..11759
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11722..12054)
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12082..14835)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15168..16394)
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 aacacatagc agctattaga gataaacaag tcaaccatta ttagggaagt acacagtatt
       61 accacaatat gacttttccg atgttcacca attccaattt agcagtatct tcaaagagtt
      121 tccattgctt gaaaccagag tttcatcggt gtgaaactgt agtttcatcg gtgagaaact
      181 agagtttcat acgcttgaaa ctttagttcc aaacgctcga aactatctga aactactgtt
      241 gatttgattg acttaaccgc atgttccaat cacattgaac gcatcagcta cttcaatagt
      301 actgctctct ctgaaaacat taaatcatat atcagtcaat aatacataaa ttatcagtcc
      361 ttaatacttg atttctcaat tattaatatc tgagaaatca aacgttaaca gttgagatat
      421 cagatattaa catcctgtaa atcaaagaat aacacagtaa aaacggtatt tatcaggacg
      481 atgcagagtg agagcaagtc cttgctctca ctctgctacc actggatctc taacagctaa
      541 aacatcgatg aataaaggga tacagacgaa ctgttagagc atgagagcaa aagcactatc
      601 tttttcactg ggggagagta agcaaaagaa acgcacgata ccggctttga ggcgtcaccg
      661 gtactaacgg caaatatccg gcacacaccc gattattctc tacggacaaa gggaacgaag
      721 ccgacatctg ccgatgttcc tccaaagcct gaccggctaa aggataataa tcaatccgaa
      781 aaactccttc cgcatccgca gccaaataac gatccgtcaa gagccatgcc accaccccca
      841 tattcattcg cagattaatt tcgacacaag gatgaatccg gtaaacaggc gcttcatccg
      901 gaaaatgaca aatcatcata tccactccca agtatccatg ataaaagcca ccgaacaaag
      961 ctgacaattc ttcttccaaa cgagtccgca gcctgataaa ttcttcttgt ggcacataag
     1021 ccgatagttt ctgcagaatc ttctcgtcag acagcaagtc attccctgca tacatcccac
     1081 tcccacccgt gtggaagacc gaatatccgg caaaaacaac ccttcctctc ccgtcagcat
     1141 aaaactccat agcgaaatct tccaccttat tatatatagg ttcgcctacc accccaccct
     1201 gagaagcagc gacacgggca caccaaccgg aaataaaagt agtaaatatg cctttacacc
     1261 aattcaatcc tttcccgctt ccggaaagcg gagcttttaa caagcacgct tcccgccctt
     1321 cgacgaacgc actgcactcc gccaaagtac tcaaataaaa agattctcca cagaagtatt
     1381 cattcaaccg caacccaggc aacaacttta ccgcctgcag acgatgcgaa tgctctctca
     1441 gaatattcat ataatccgca gaaggcagct ccgtctgatc tgcccccaat gtcatcaaac
     1501 gcttccgcaa agcagggtcc cacccccacg gagagaactt ccggtcttta ccgtcagcca
     1561 cttccggttc cgtcaacaag gccacatcca tgcccaaaag ttcactcttt gttttcagga
     1621 agtccgcatt ataagcagac ggtgcaagca ccgcacttcc cgcttcggca taccacatag
     1681 gaagcaacgc caggtcactc gccatctgtc gggcggaagc cggcgccata tagttcgtct
     1741 caccgcttgc caacgccata tcatgctccg gattgaatat ataaacaggt cttttcgtca
     1801 tgtcaaagat ggattcaaca cattattctg caaatatata caggaaataa tcaggaactt
     1861 acacaataaa gagaaactta taaattaaag cacatttttg ctatctctac tttgcaaatc
     1921 ctaaaaaaag cactatattt gccagccgaa aaacaaagaa acgaaatgga atcattctat
     1981 cgcacacacg cctacctcgt tgagcacacc aatgcccccg ttcgccgcga tcttatggac
     2041 gagatcgact ggagtgaccg tctgattggt atcaaaggga cacgtggcgt aggaaaaacc
     2101 actttcctcc tgcagtacgc caaagagaaa ttcggcaccg accgttcctg tctgttcatc
     2161 aatatgaaca acttttattt ctccggtcac agccttgttg acttcgccaa cgagtttcag
     2221 aaacgtggcg gaaaagtact gctgatcgac caggtgttca aacatcccga atggagcaaa
     2281 gagctacgaa tgtgctatga ccgtttcccc agcctgaaga ttgtcttcac cggttcttcc
     2341 gtcatgcgac tcaaagagga aaacctcgaa ttgcgtgaca ttgcgaaaag ttataacctg
     2401 cgcggattct ctttccgtga atttctgaac ctgcagacag gaatgaaatt ccgggcatac
     2461 agcctcgaag aaatcctcag tacacatgaa cagatagcca aaggagtact ttccaaagta
     2521 cgaccgctgg attattttca ggattacctg catcatggtt tctacccttt cttccttgaa
     2581 aaacgtaatt tctcggagaa tctgctgaaa acaatgaaca tgatggtaga agtggatatc
     2641 ttgctgatca aacaaattga gctgaaatat ctttcaaaga taaaaaaatt actatatttg
     2701 ttggctgtgg acggaccgaa agctccgaac gtgagccaac tggcaagtga cgtacagaca
     2761 tcccgcgcta cggtaatgaa ctatatcaag tatctggcag acgcgcgtct gattaatctg
     2821 gtttacccga aaggagaaga attcccaaag aaaccgtcaa agattatgat gcacaactct
     2881 aacctgatgt actccattta tccggtgaaa gtggaagaac aggatgtact cgacacgttc
     2941 ttcgttaaca ctttatggaa agaccataag gtacataaag gagataaaaa cgtctctttc
     3001 atggtagacg aagtgatgcc gttcaaaatt tgtgcggaag gtacaaaaat aaagaataac
     3061 ccggacgtga cgtatgcgtt gcaaaaggct gagataggcc gcggcaacca aatacctctt
     3121 tggatgttcg gattcttata ctaaaaagat ttatttactt aaatatttaa tttagttatg
     3181 actaaacaga agaaattcat cacttgtgat ggtaaccagg ctgcagcaca tatctcgtat
     3241 atgttctctg aagtagcggc tatctacccc atcactcctt cttcgactat ggctgagtac
     3301 gtagacgaat gggctgccgc aggacgtaag aacatcttcg gcgaaacagt attggtacag
     3361 gaaatgcaat ctgaaggtgg tgctgccggt gcagttcacg gttctcttca ggctggtgca
     3421 ttgactacta cttacactgc ttctcagggt cttcttttga tgatccctaa catgtacaag
     3481 attgccggtg aattcttgcc ttgtgtattc cacgtttctg ctcgtacact ggcttctcac
     3541 gcattgtgta tcttcggtga ccatcaggac gtaatgtcag ctcgtcaaac cggcttcgct
     3601 atgttggcag aaggttctgt acaggaagtt atggatttgg caggtgttgc tcatctggct
     3661 actatcaaat cacgcgttcc gttcatgaac ttcttcgatg gtttccgtac ttctcacgaa
     3721 atccagaaga tcgaaatgtt ggaaaacgac gacctcgctc cgctgatcga ccaggaagct
     3781 ttggctgaat tccgtgcccg tgcactgaat ccgatgaagc cggttgcccg tggtatggct
     3841 gaaaaccccg accacttctt ccaacatcgt gaatcatgca ataactacta tgaagcagtt
     3901 cctgctatcg tagaagaata catgaacgaa atttccaaga tcacaggccg caaatacggt
     3961 ttgttcgatt actacggtgc agaagatgca gaacgcgtaa ttatcgcaat gggttctgta
     4021 actgaagctg cccgcgaagc tatcgaccac ttggtagcaa acggcgaaaa agtaggtatg
     4081 gttgccgtac acttgtatcg tccgttctct gctaaacact tcctggctgc tgtacccaag
     4141 actgcaaaga gcatcgcagt gcttgaccgt acaaaagaac cgggtgctaa cggcgaacct
     4201 ctttaccttg acgttaaaga ctgcttctat ggcgcagaaa atgctcctgt tatcgttggc
     4261 ggtcgctacg gtctgggttc aaaagataca actccggcac agatcatctc tgtattcgaa
     4321 aacttggcta tgccaatgcc gaagaaccac ttcactatcg gtatcgtaga cgacgttacg
     4381 ttcacttctc ttcctcagaa agaagaaatc gctctgggcg gtgaaggtat gttcgaagct
     4441 aaattctacg gtctgggtgc tgacggtact gtaggtgcca acaagaactc tgttaagatt
     4501 atcggtgaca acaccgacaa acactgtcag gcttacttct cttacgactc caagaagtcg
     4561 ggtggtttca cttgttctca cttgcgtttc ggtgatactc cgatccgttc tacttacttg
     4621 gtaaatactc cgaacttcgt tgcttgtcac gttcaggctt acctgcacat gtacgacgta
     4681 acacgtggtt tgcgtaagaa cggttctttc ttgctgaata ccatctggga aggcgaagaa
     4741 ctggctaaga acctgcctaa caaggtgaag aaatactttg cacagaacaa catctctgta
     4801 tactatatca acgcaactca gattgcaatg gaaattggtt tgggcaaccg taccaataca
     4861 atccttcagt ctgcattctt ccgtatcaca ggcgtaatcc ctgtagatca agctgttgaa
     4921 cagatgaaga aattcatcgt taagtcttac ggcaagaagg gtgaagacgt tgttaacaag
     4981 aactacgctg ctgtagaccg cggtggtgaa tacaagactc tgactgtcga tcctgcttgg
     5041 gctaacctgc cggatgatgc aaaagcagaa aacaatgatc ctgctttcat caacgaagta
     5101 gttcgtccga tcaatgcaca ggacggtgac ttgctgccgg tatctgcatt caagggtatc
     5161 gaagacggta cttggtatca aggtacttcc aaatacgaaa aacgtggtgt agctgcattc
     5221 gttcccgaat ggaatgctga aaactgtatt cagtgtaaca agtgtgctta cgtttgtcct
     5281 cacgcttcta tccgtccgtt cgtactcgat gctgaagagc agaagggtgc taagttcgag
     5341 caactgaaag ctgtaggtaa agcattcgat ggtatgacat tccgtattca ggtagacgtt
     5401 ctcgattgtc tgggttgcgg taactgtgcc gacatctgtc cgggtaatcc gaagaagggt
     5461 ggcaaggcat tgaccatgaa acaccttgaa agccagttgg ccgaagctga taactggact
     5521 tactgcgctg aaaacgtgaa gagcaaacaa cacctggtag acatcaaggc taacgtgaag
     5581 aactctcagt tcgcaactcc gttgtttgag ttctcaggcg cttgctccgg ttgtggtgaa
     5641 actccgtacg tgaaactgat ttctcagttg ttcggtgacc gtgaaatggt tgctaacgct
     5701 acaggatgtt cttctatcta ctccggttca gttccttcta ctccgtacac tatgaacgaa
     5761 aagggtcacg gtcctgcatg ggctaactcc ttgttcgaag acttctgtga atttggtctg
     5821 ggtatggaac tggctaacga aaagatgcgt gcccgtctgg tgaaagtaat gaacgaagct
     5881 atcgcttctg attgctgccc ggctgaatac aaagaagtat ttgctgaatg gatcaacaat
     5941 atgctggatg cagaaaagac taaggaactg gccgaaaaga tcattccgat ggtagaagct
     6001 gctaaagata aatgcaacca ctgcaagcaa atcgctgatc tgcaacaata tcttgttaaa
     6061 cgcagccaat ggatcatcgg tggtgacggt gcttcttatg atatcggtta cggtggtctt
     6121 gaccatgtaa tcgcttccgg taaggacgtt aacatccttg tattggatac tgaggtttac
     6181 tctaacacag gtggtcagtc ttctaaagct actccggtag gcgctatcgc taagtttgct
     6241 gctgcaggta agcgtgtacg taagaaagac ctcggtctga tggctactac ttacggttat
     6301 gtatatgttg ctcagattgc tatgggtgct gaccaggctc agactctgaa agctatccgt
     6361 gaagctgaag catatccggg accatcactg atcatcgctt acgctccatg tatcaaccac
     6421 ggtctgaaag ccggtatggg taagagccag gaagaagaag aaaaggctgt taagtgcggt
     6481 tactggcact tgtggcgtta caaccctgct ttggaagaag aaggcaagaa tccgttccaa
     6541 ctggatagca aagaacctaa ctgggaagac ttccaaggtt tcttgaaggg tgaagttcgt
     6601 tacgcttctg taatgaaaca atatcctgct gaagctgaag aactgtttaa agctgctgaa
     6661 gaaaacgcta aatggcgtta caacagctac aaacgtcttg ccagagaaaa ctggggagct
     6721 gatacagctg aataataagt agaaatactt tgtacataat aaaaggcagg aatcctggaa
     6781 acagattcct gccttttttg tttatatctt agaagtaacg attacttctc acgaagatat
     6841 tcattaaaac tctaaagata tgatcggatt tgttatttgg attatcggtt tgatactgac
     6901 tttcagagct gccatagaga tttggaatat aaatgcggct gtagagaaaa gacttatagc
     6961 gattgtatta atcgttctta ccagctggct gggactactt ttctactact tctatggtaa
     7021 agaaagaatg gcgggatggt tgaagtagtg tttgcatatc aatctttctc aggaatccaa
     7081 ctgttcacca gttcctgatg ttcttccatc cattgacggg cagcctgtct ttccgttgtc
     7141 tgcgcctctt ccagagcagt cattaaggag ctgatttccg catctgtcag acgaatgttg
     7201 cccaaaagtt cggcagcaaa agggtctttc tcgctaaaac ctttccatgc tatggtatga
     7261 atggattccg tatttccata tatcagcttc gggtcctgaa gaactttcag cttgaaacgg
     7321 tcgaacatcc agtgaggcgt ccatcccgtc acgacaatcc agtctttctt atcaatcgct
     7381 ttctttaggg aagcagtcat ggcaggtccg ctcgaagtca tcagtttata atccaatcca
     7441 tagtctttga tggcctgatc ggtagctttc ataataccgg ctccggcatc aataccgaca
     7501 atctgaccgg agaaacgttc cttttccgcg ttcagttctt cgattgagtt gatcgtaacg
     7561 taatccggaa ccaccagccc gatacgggca ccatcataaa tatccccgat aacttcgagt
     7621 ttatccccgt attgtttcat ataatcttcc atagtgacag gcatccagac atccataaat
     7681 acgtctgctt tcttacggga gatagaggta aatataggtg caaggtcggc attcagcaac
     7741 tttacatcgt acccctgatc ttcaaaaatc gctttggcaa ggtttgtcat tgcaatacct
     7801 tccgaccagt tggcataagc gatacttatc ttcttactct ttccgttgtc tccgcaggaa
     7861 acgaaggtta agagtatgcc ggcaataaac attgccgcaa tcatttttat cttattcatt
     7921 gattattcct ttctttggtg tgattcttat ttctttttac tttttctgtt atctgccata
     7981 ccctgagtga tgcggtccag cacgatcgcc aatatcacga ctgcgatacc gccttcaaat
     8041 ccgagtccga ttttcatttg ggtgatacct ttcagcacga tttctcccaa tcctccggca
     8101 gaaatcatgg cagcaatcac taccatcgaa agtgacatca tgatcgtctg gttgattccc
     8161 gtcagaatag taggcaacgc caaaggcaat tgcaccttat aaagaagctg ccagggagta
     8221 gctccaaaag agcgggaggc ttctactacg tttttaggaa cctgacgaat gcccagaccg
     8281 gtcagacgaa ccacaggagg cattgcaaag atgatggtgg caaaagctcc cggcacagtt
     8341 cccaatccga agaatagaac ggcaggaatc agatagacaa aggcaggcat tgtctgcata
     8401 aagtcgagga cagggcgcat tatcttgtta caacgatcac tgttggcagt ccagattccc
     8461 aacggaacgc ctaaaagcaa tgccagacaa gtggaagaaa gtaccaatgc caatgtctgc
     8521 atcgtttctt cccaaaagcc catgccgtaa ataagcaata aacccaagag ggtaaatacg
     8581 gctgtcccct tacccgactt aaaccaggcg agcgcagcca gcactgcaat tgtgatataa
     8641 aaaggtattc caaacagtac gtgctgaaaa ccgtctatga atcctccgat ccccatgctg
     8701 agagcatcaa aaaaggaagc aaaatgttct gtgagccaat taatggcagt ctctatatat
     8761 tgtccgatat ttatcataat tctattgcgt tttgaatgat ttcattaatt tcttctttat
     8821 cttttcccgt tacttcgatg atcaatgagg aaagtggcac tacgccttca aactcccgat
     8881 tctcatttac gacccagatt ggcgagttcg tttttgtcat caacggaaga atatcttcca
     8941 gcaccgtatc acccagcact gaatgaactt catgccttac tacggactcg atggagcgga
     9001 tttgctcttt tcgtagtttc agcaagtcat tcaaccgcac ctctcctact aacagattat
     9061 tggaatcgac taccggaaga acggtcagat tccgttcgcg catcttacgg atcagcacct
     9121 ccgggccttc tttcttcaaa cgtgccacta tgggtttatc taccataaca gaggaagctg
     9181 ttataatctt gcttcgatct acattctcca caaatcgttc tacataagcg ttggcaggtt
     9241 cggtcaggat ttcttccgat gtaccgattt gtacaatttc tccatccttc atgatagcaa
     9301 tccggtcacc caatttaatc gcttcactca ggtcgtgagt aataaagaca atcgtttttt
     9361 tcatcttcga ctgcaaagtc agcagttcat cctgcatctg cacacggatc aaaggatcga
     9421 gtgccgagaa ggcctcatcc atcaacagga cttcgggatt attggccaaa gcccgcgcca
     9481 gcccgacacg ctgctgcatc ccacccgaca gttcacttac catctgattc tcgtagcctt
     9541 tcagccccac cagttgcata ctttccatcg ctttctgctc ccgttctccc ttttttactc
     9601 cctgtagttc gagcccgaaa gctatattat gcaagacaga acggtgagga agcagaccga
     9661 agttctgaaa gaccatagcc agttctttcc ggcgaatctg caacagttcc ttatccgaca
     9721 ctttggctat gtctgttcca ttgataatca cttctccgga agtagggcgt atcaaacggt
     9781 tgatgcagcg gagtaaagtg gactttccac taccggacag ccccataatg acgaatattt
     9841 cgccttcatt aatggaaaga ttcgcatctt tcaccgcaac tgtacatccg gtcgctttca
     9901 atatttcact ttttgtttta ccttctttca acatcttcaa agccttctgc ttctcattgc
     9961 caaaaaccag atagagatct ttaatttcta ttttactcat acaataaaat ggtttaggtt
    10021 attaaaataa tatacacagc aagacaagaa caaacgataa caggaatctt tctttatatc
    10081 gtataaagtt ctgatttaaa taagggacaa ataacaatga atcccgaaat aattaataaa
    10141 atgattattg acagactgag taattaaaaa aggaatagaa tttgataaga taatcctttc
    10201 aacgaatagc aaaaaatagc atttttatgt ataaaaacag cctgttccag tatcttgctg
    10261 gcacaaagat acaaaaaacg gattaaacat acaaattata ttcaaaatcc ggggcataca
    10321 gagggcttta tttgtaatga tatggaaagt ttccgggtaa tattccccta tcactcagca
    10381 aaatagaaca aaccggcaga taaatataaa ataagtttga atatttcact taaacaccgt
    10441 atatttggcg tcaataacta aactagattt atatgttcaa cagggctatt acaattttcc
    10501 tggggaagga taattgtcat tacacaacaa aagaaaaaca aacaggtact gccacactag
    10561 acgacaaaag ccaagtacag ttccttagta aaaagaaccc caaaatgccg tttttctata
    10621 gccggcggaa tctctacatg ataggtttcc tgctcgcttt tatagtgact ctgctcgaat
    10681 ttatacgagg acggcatcaa aactttatgg tcttctcgga cgctactcaa ttcttctggc
    10741 aaggcatcag cccatacaca actgaatttg tagaagctca cggacgctac ttcctttatt
    10801 ctccagtttt cacggtattg ttcgctccgt ttgcgtatct gcctgcatgg ctgggacctt
    10861 tcgcgtggaa tctattcaat tattcgctgt tctttatggc gatcttcacg ctgccccaac
    10921 aattcaccca gcagcagaaa tgccgtatgt tcctttttct gttactgatt ttaggacaaa
    10981 gtttactttc atttcagtat aacataacgg tagcctattt attcttattc gcctatacgt
    11041 tattggaaaa agaccgtgga tttctggctg ttctgttaat catgatttcg ggatgtacca
    11101 aagtatatgg aattttcgaa ctggcattgt tgctgtgcta tcctcacgta tggcgtaact
    11161 ttggctatgc cgttacaatg ggcattgtat tgcttgcatt accgttaatc aaaatagctc
    11221 ctgcagattt gctcccctat tatgaagaat ggtgccatag tcttgctgtt catcagtccg
    11281 ccggagctta tgattcattt ttctatgccc gccccattgc agcatggaca ttgccacact
    11341 tccgtgcact tcagatagga atgctcggct tgctgactct gctctttttg gggaatttcc
    11401 gcaaatggtc gtcttttgcc ttccgtgccc aggctttggg cattctcatg ggctgggtag
    11461 tattactgag tgactccgcc gagaagcata cctatattat cgcattggca ggtttcatgc
    11521 tctggtattg gagcagacca acacgtaccg caacagacaa gattctattt tggtgctgtt
    11581 ttgtgctgtt atgtatcgtt cctatcgaca tattcgtccc tatacccatc agagatttca
    11641 ttaccaggac cttatggctt catgtatggg ttttctttat tgtatggata cggatgatat
    11701 ggcttacctt ccttgcatcc ttcattcatc cacgtgccac aaatgttctt tcagattaac
    11761 gcatccgtta gctttgaaag aaacttcttc tgccagcaag agttgttttt gttccaccca
    11821 accgggcacc agccttccgg tggaatttac aactctatgg cagggaatgg ataattcatc
    11881 cggcacttct ttcaatgcac gtcccaccat ccgcgagcat tggggtgccc ccaacagcaa
    11941 agcaatacct ccataagtag atacttttcc cacaggtatc tgggatacga cttcgtacac
    12001 ttccttccga aaggattcgg aaaagctctc tttatctact ttataatctt tcatatatcc
    12061 ctctttacga tatcaatgaa atcatccttt ccttttcagg aaatctgtcg ggctctctcc
    12121 aaactgctct ttatagcact tggcgaaata agaaggtgaa ctgaaaccga cttcataacc
    12181 aatctccgct acggtcatgt ccgaagaagc aagcaaagaa gctgccttct tcaaacgggc
    12241 gatacggagc aattcattcg gagagtagtt agtcaatgat ttaatcttgc gataaagctg
    12301 cacacggctt agtcccatgt ctttgcccaa gtcctccaca ttcaaaccgg agtctcccat
    12361 tttctcttca atcaatgact tgaatctttc tacaaaatcc ttgtccatat cgcagacatc
    12421 ttcttttgcc aatgtctgcc cgtcaccaaa gaactgtttc agacgacggt gagaatcgat
    12481 cagattgcgg acacgtgcca gcaacagctg tgaactgaac ggctttgaaa tataagaatc
    12541 cgcaccaccg tcatatccct gaatacgctg ttcgtccagt gaacacgctg tcagcagaat
    12601 aaccggaata tgacaggtct gtaactcact tttcagccgg cggcaacatt caatgccatc
    12661 aatgcccggc atcatcacat cagaaatgat caggtccgga acatacttca tagccttacg
    12721 gattccttcg gagccgtctg ccgcttcaat caccgtatag tctgtatgca acaacgtatg
    12781 gacatacgaa cggatatcct cattatcatc aataatcagt acggacggtt tggaagagtc
    12841 atatcctttt tccagttctt cctcttccgc caatagaaca tctgttgtac gggaatccgc
    12901 agaaacaagg gtggtatccg gttcggcagc aacagcctca caagactgta caggcagttc
    12961 aacggtaaag accgtgccct gtttctcatc gctctctacg gagatcatac caccgtgcat
    13021 ttctacgaag gcttttacca atgccagtcc gattcccgaa ccggtatggt gcatatcgat
    13081 cttatagaaa cggtcgaata cattgcgaat atgttcggca gaaatcatag aaccggtatt
    13141 tgccaccgtg aaacgtatcc atcgcttgtc ctctttacta agggaagaca gacggacggc
    13201 tattttcccg ttttccggtg taaacttaaa ggcattggac agaagattga aataaatacg
    13261 ttccagcttc tccatgtctg ccagtgtatg ataatccgta tccggcatac tatcaaaaga
    13321 aaaatggata tgcttcttac gggctgccgc ctgaaaagac tcattccatc cttcgaaaga
    13381 agaaaggaca tccaccgtaa ccggagtata ttccatcttg ccgttttcat atttacggaa
    13441 atccagaatc tgattgacca gacgcagaag aatgttcaca ttccgctgaa tcagcatgag
    13501 catccggtgc tgatctccgc tcagtgtctt gtccgccaac aaatgttcta ccgggtcggc
    13561 aaccaatgtc aacggagtac ggaagtcgtg agaaatattg gtgaaaaaga ccagcttggc
    13621 atgggtagct tcttccagtt gatgagagag ctgtatcaat tggtcacgct gttcttccag
    13681 tttgtcacgc tgctcttcca attgctgctt ctgcttaaaa agctctttat tcaagcgatt
    13741 cttagagcgg agtgatttat aaacgaccaa taataagccg gctaccaata aaaggataat
    13801 cagactgccg tataaaacga cctgttgtgt agctacctga gagagatagc caccgatacg
    13861 tccgttgagc gtttcaatct ttttgtcgag ttcggaaatg tgtgtggtct gcaactgcat
    13921 gacgtgtgcg ttggtacggt ccacaacagc ggtattcatc accgtttctt tgggataggg
    13981 tttcttctcc agaatgtcca tagccagttg cagtacctta tcgccattgg tcggatagat
    14041 aaaggtggca tccagcacac tgtccagtac cagttccagt ccgtttccct tacccggcaa
    14101 ggcatctatg ccgacaaaaa tcatttcctt ctcccgccct gccatctttg ctgcctgata
    14161 ggcacccgga gcgatacggt cattatgggc atacacagca tcaatcttag gatgcctccg
    14221 aagcatacta tccatttcta tctctgccgg accacgttcc cacgcagcat ccgctttatc
    14281 aatcagcttt atatccggga atttactgat ggcagccata aatccctgat gccgttccat
    14341 tgcaggagtc gaaccgctca atcctgtcag ttctactata tttcccttcc ctttcagact
    14401 ggaggcaata tagtttccta ccgaacgacc gatttcataa ttatcggctc cgatataggc
    14461 agtatattta tccgaaagaa tcttccggtc tacaagaata acggggatgc ctttctgata
    14521 agcttcttct acaatcggag tcataggagc agcttcgtta gcggaaataa tcagcagatc
    14581 gactccttcg tccataaaat aatggacatc ttccgcctgc ttactgttat catcccctgc
    14641 cgaacggatt tccaccgaaa caccattata aaacatcgct tcccgaagaa tctcatcatt
    14701 catcttatgt cgccatgaat catcgctgca ttgagccacc ccaatacgaa aacggggtgt
    14761 atcctgccgg caagccgtca tcccgattaa accaaacagc accagcatcc acttcagata
    14821 tctcatcgtc ttcatccatc tcatcatttc atagttcttt ctgtaatcca attaagaaca
    14881 aaaataagaa ataatactgt aaagttctct aacttcagct atttattatt ctaaaaagaa
    14941 ggaaagcagt cctctttcag accatcggaa agtattaaca aaagtataaa gcgtaaaaca
    15001 aacacttaat caatgttata aaacatagcg ttttacttgg ataatttgca gatttcacag
    15061 aagtccgtat ctttgcactg tgtttttcat agtattagat ttaaggttaa caaaggttgg
    15121 agcaaggcgt tgctcctttt tttatgctct gacctttcat ctaccggtta gttttcatcc
    15181 cattcctttt ccagtttacc atcaatagtg tagcgtttcc atcgtcctac acggtgacca
    15241 ttcttatatt ccccacattc acgaagctgg tcattcttta cataacgagc ttcgaacggt
    15301 ccgttctgcc ttccgttcac ataggtagaa gtttcccaat aatcaaagcg gttgctcact
    15361 atcagccgtc gttccttgcc atgcaatctg ccggcctgat aggtagcttc atatctcaat
    15421 tcaccatttt ccaaattata ttcacggtat aaaccgtctt tacgatcgtt cttcatataa
    15481 tattctttct gccttacccc acttccgttg gcaaatgaga catggagtcc atcttctttt
    15541 ccatccagat aggtttcaat catcagcgta tctccgcttt cagcaaaagt agtccaacga
    15601 ccattcttct ttccattctt ataactaccc agtatacgtg gcgagccaaa cgtaaacacg
    15661 gacgaatatt caccgtcctg aaaaccttct tcattgaaat aaacggtctc atacaaatca
    15721 tatgtacctt tcagaaaagt atactgtttg cctacctgct tcccgtcctt gtaattatgc
    15781 tctttccgca aagtaccgtc agattcgtac gacagttgct tcccgtgctc tttccccatc
    15841 cggaagtttc tttcactttc cacttttccg gtagtaaagt aacttttgct cgtaccgtcc
    15901 agcttacctt ccttatagga cttttcttct ttcagcttac cgtcaaactt ggagttaatc
    15961 ttgaagaggc catccttccg cccttcttta taacttcctt ccgttattaa tatattgtcc
    16021 acatattctt tgtatccgcc atcataaaaa ccatctttaa aagatgccag cacataggcg
    16081 gaatgataac catctatgat gcgatgttcg ccattcaatg ctttttccgt tttcagttcc
    16141 tgaaacaaca gtctgccatc gcctacatta acaacagata cctgatcgat cttatattcc
    16201 ttttgcgcaa acaaaggaag agcaagatat aaaaacaaaa atacgttcca gctttttgat
    16261 ctgaggaagt tcgaaatgtg tttcataaag tagttttctc tttttgattt attatttaaa
    16321 aacctgccgc aaagataggc aatcggctta taaaacaagg caagaaagag ggggacaatt
    16381 agaaaaaaga acatctgtta ttatcattct aataattaac agattaagta gtaaatcaaa
    16441 acacagggaa gggggacatt tactgaaata agaaacagaa aagaagatgt gtcaaaagca
    16501 actaaattcc cctccttcag gaaggaggag agtttagtta cttttgactt ttgacacatt
    16561 tacatttgca gtatt
//
