LOCUS       gnlProkkaADIJIICD_84   12393 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADIJIICD_84.
ACCESSION   gnlProkkaADIJIICD_84
VERSION     gnlProkkaADIJIICD_84
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:03:14
            Original ID  :: gnl|Prokka|ADIJIICD_84
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 28323
            Orig. end    :: 40716
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12393
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10354]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10354
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12393
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12393
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(337..1674)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 123.8; E-value: 1.7e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_28"
                     /sec_met_domain="CTP_transf_like (E-value: 3.3e-18,
                     bitscore: 57.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVITYGTYDLLHQGHLNLLRRAKSLGDYLIVGVTTDNFDLDRG
                     KLNVRNNVMERIESVRRTGLADEIIIEEYVGQKIDDIQRYNIDVFAIGSDWRGHFDYLK
                     EYCDVVYLDRTEGISSTQLRNESCVRLGIIGTGRIAHKFIPEVAFVNGVNITTVYNPDQ
                     ESASSFSEQFGISHVSCSFSELCKHIDAAYVASPHLTHYDYVKQLLDCGKHVLCETPLT
                     LSFSEAQQLCELARSKGLTFMEANKTAHCPAFNHLITLIKSGLIGTIVDIDASLSTLKV
                     QGVRELDSFQAGGSVTENLSFALLPVFKLLGTNYKEVMFFSSFKDGVDIFTKGILRYDS
                     AIASFKLGLGVKTEGNLVISGTKGYAYVPAPWWKTDYFELRYEDTNQNKKYFYTYAGEG
                     LRYELQEFVSCINNGLCNTHRLTYSEMITMAGIIEKFRRGEHVEFL"
     CDS             complement(1683..2720)
                     /NRPS_PKS="Domain: Aminotran_5 (25-265). E-value: 4.4e-25.
                     Score: 80.2. Matches aSDomain:
                     nrpspksdomains_ctg84_29_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_29"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-21, bitscore:
                     68.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFVFPGNIESDILGISSLPIPYMRTSSFSSLVQDCESMLLRLI
                     GCPNGRVIFYTASGTGAMDAVVTNYVSLKHKAFVVAGGSFGYRWKSLCDYYDIDVDLYE
                     VPFAKDIDYSDLEAKIALSHPDVFLCQQHETSTGQMFNLDKISYICKKYHVSLVVDAIS
                     SFLADPLHMSDLGIDICITSSQKGLNIAPGLSFVILSQNISDMHFASSGYYFDFNENLK
                     NLQRGQTPYSPATTIFLQLHERLKRNVQIGVDSIISRVRERALFFRTLCNKYNWIVPAE
                     VPSNCITGFFINRNGDILFKELLDREIYIMPGGTPNYFRVSHLGVQDKQDLLCLSEEIY
                     RIEQL"
     aSDomain        complement(1926..2645)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_29_Aminotran_5.1"
                     /evalue="4.40E-25"
                     /label="ctg84_29_Aminotran_5.1"
                     /locus_tag="ctg84_29"
                     /protein_end="265"
                     /protein_start="25"
                     /score="80.2"
                     /tool="antismash"
                     /translation="RTSSFSSLVQDCESMLLRLIGCPNGRVIFYTASGTGAMDAVVTNY
                     VSLKHKAFVVAGGSFGYRWKSLCDYYDIDVDLYEVPFAKDIDYSDLEAKIALSHPDVFL
                     CQQHETSTGQMFNLDKISYICKKYHVSLVVDAISSFLADPLHMSDLGIDICITSSQKGL
                     NIAPGLSFVILSQNISDMHFASSGYYFDFNENLKNLQRGQTPYSPATTIFLQLHERLKR
                     NVQIGVDSIISRVRERAL"
     CDS             complement(2744..3136)
                     /locus_tag="ctg84_30"
                     /transl_table=11
                     /translation="MKNSLCNSVSSVVKKLLEYGGDGTPVYVNELTALNKELRNLCADL
                     LLQKGKSPEEEAEILVTLFKGYDTMLFNFSLENEQVVQELLDRSMTVLEKLPASVLKCQ
                     LLLECFEQMGDEELIREVKNIVNRLA"
     CDS             3155..3307
                     /locus_tag="ctg84_31"
                     /transl_table=11
                     /translation="MIRRFFFGFYLYRKSNFSFRSRFTPSEPIYLCLSSINIVNVFFRL
                     FGSCA"
     CDS             complement(3671..4189)
                     /locus_tag="ctg84_32"
                     /transl_table=11
                     /translation="METTDSDKHWYVVLTRTNSERKVRDYFQLQEVDTFLPVQNRVIER
                     EGKRIERERLLLPRMVFVHISRQEMAAVRSTLNVYDFLRDRSTGAPTCIPDAQMADFRY
                     MLDYSQDQVILTGESIPKGTRVVVAKGDLQGLRGELVRYNNKYHILVRIDMFGSAMVTI
                     PASYVRKEK"
     CDS             complement(4570..4755)
                     /locus_tag="ctg84_33"
                     /transl_table=11
                     /translation="MLTSYSSLIKILLFDNQLLIFWMRSAVKFFSYIQDVRSCLFIKLP
                     LRLSIACLSTYFHILL"
     CDS             complement(4903..5454)
                     /NRPS_PKS="Domain: oMT (22-123). E-value: 6.9e-16. Score:
                     49.1. Matches aSDomain: nrpspksdomains_ctg84_34_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 102.3; E-value: 5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_34"
                     /transl_table=11
                     /translation="MNTGHASLAQWGMSCLQWQPEWSVLDIGCGGGANLLQILQRCPQG
                     KAYGIDISPESVTFARKKNKKYLGTRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNL
                     QHAFTEVARVLKPGGSFLICCEISDPANKAWTGLVEGMEIHSCDELKAILSKSGFTDTA
                     IFRTKKEELCLVSHRQTVRL"
     aSDomain        complement(5086..5388)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_34_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.90E-16"
                     /label="ctg84_34_oMT.1"
                     /locus_tag="ctg84_34"
                     /protein_end="123"
                     /protein_start="22"
                     /score="49.1"
                     /tool="antismash"
                     /translation="SVLDIGCGGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKY
                     LGTRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLI"
     CDS             5844..7184
                     /locus_tag="ctg84_35"
                     /transl_table=11
                     /translation="MNNVQQVKTYSQRKISDFLFILWAGGAALLSYSLVYALRKPYTAA
                     GFDGLEAFGMDYKVVVTIAQILGYVLSKFIGIKLISELKRENRMKFILISIILAEASLI
                     LFGLLPAPYNIGAMFLNGLSLGCMWGIIFSFIEGRRMTDILASLLGVSMVISSGTAKSA
                     GLYVMDTLNISEFWMPALIGGVALPLLALLGYALNRLPQPTAEDIAMKSKRETLNGKQR
                     WELFKNFMPFLTLLFIANVVLTILRDIKEDFLVKIIDVSQYSSWMFAQVDSVVTLIILI
                     IFGLIVFVRSNLKALSILLGLIIASMVVMAVVSFGYEQLQLNAIVWLFIQSLCLYLAFL
                     TFQTIFFDRFIACFKIRGNVGFFIAMNDFLGYTGTVIVLAVKEFFSPDINWTAFYNLMA
                     GYVGIICFVAFVCSFIYLHQRYRRENYGKTGVFRKKEEEKEVPDFVY"
     CDS             7585..8739
                     /locus_tag="ctg84_36"
                     /transl_table=11
                     /translation="MDHLVVDGLFGSGLNKPLSGGFAAVVKYINASPATVVAIDIPSGL
                     MGEENTFNVKANIIRAQLTLSLQLPKLAFLFAENSEFVGEWKLLDINLSREAIEETESN
                     YALLEAEEIHALIKPRNTFSHKGNFGHALLIAGSYGMAGASILAARACMRSGVGLLTVH
                     APIRNNDILQISVPEAIIESDASDTYFACPTDTDDYQAVGIGPGIGRSEETEAALLEQL
                     SGCQTPLVLDADALNILANHRHALTTLPKGSILTPHPKELERMVGKCQNSYERLMKACE
                     LARTAKVHIILKGAYSAIITPSGKCYFNSTGNPGMATAGSGDVLTGVVLALLAQGYPAE
                     EAAKIGTYVHGLAGDFARKKQGVISMTAGDIISNLPLAWRLVSE"
     CDS             8812..9867
                     /locus_tag="ctg84_37"
                     /transl_table=11
                     /translation="MKKLIILTGLLLSTSAYAQTEVTAGVTRGKDYGVTYALPKTAINI
                     EVKVNKVTYTPGEFSKYADRYLRLTDVSGEPQEYWELVSVKAKSVGIPDSEHTYFVKLK
                     DKTVAPLIELTEDGIVKSINVPLSPKKSAPMQPATTQKKKINPRDFLTEEILMAGSTAK
                     MAELVAKEIYNIRESKNALVRGQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKD
                     EKIFNIRLTPDKEMDNEVAFRFSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKK
                     VDGIAYNVPGKAQVTLTEGKKQWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTG
                     GLIKVDREEGE"
     CDS             complement(10001..10354)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_38"
                     /sec_met_domain="PF05402 (E-value: 6.1e-17, bitscore: 53.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.5e-10, bitscore:
                     29.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSADIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(10361..11623)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 82.1; E-value: 5.1e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg84_39"
                     /transl_table=11
                     /translation="MLEKELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFT
                     GMGACILMVLGCGLKYYAISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIAGITVSK
                     IIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNIPMPILL
                     CLIMLCIGTIAFFIYTFYDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWLIALLCV
                     LFYSAVFPFIKYATDLMVQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRIGKGATL
                     MIIGAVMLIGVHTLFALPILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIPEKQLGT
                     AYALIFWVQNWGLMGVPLLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGVLALIVA
                     LMLKAEDKKKGYGLQEANIKK"
     CDS             complement(11920..12300)
                     /locus_tag="ctg84_40"
                     /transl_table=11
                     /translation="MYLLLVILMVIAAILMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWGLAAFMVVMSIATAYVVPTSSSKTQDVIMEQAQQEEQTNPYNLPVGTTA
                     PKTDAAAPVEAPATETPATPAN"
     CDS             complement(12305..12391)
                     /locus_tag="ctg84_41"
                     /transl_table=11
                     /translation="MLKYPKKNAYFADQIRFLEKLIINAKSK"
ORIGIN
        1 aaaaaagcgg agttggggat atttagattc cggatatttt tgtttaagtt caaattgctt
       61 caattcatca cgagaataga taacaattcg tttaacattc ggataatccc gaaggattgt
      121 ttccacaaac ttcttaccga aagaacctgt tccaccggta attaagactg atttactatt
      181 aagcatatat tacatttata tatattttta atcacctata ttcttaaata catttttata
      241 cgactatagc ttaaaaatta ttatttttaa atacctgaca tatatcagca aaataacatt
      301 atattaaaaa gcatataaat tttgtaacta tttacactat aggaactcaa catgttcacc
      361 ccttcggaat ttttctataa tcccagccat agtaatcatt tcagaatagg ttagccgatg
      421 cgtattacaa agtccattgt ttatgcagga tacaaattcc tgtaattcat aacggagacc
      481 ctcgcccgca taagtataaa agtatttctt attttgattt gtatcttcat aacgaagttc
      541 aaaataatca gtcttccacc aaggtgcagg aacataagca tatcctttag tacctgaaat
      601 taccagattc ccttccgtct tgaccccaag ccccaactta aaggaagcaa tagccgaatc
      661 atagcgtaat atccctttag tgaaaatatc aacgccatcc ttaaaagaag aaaagaacat
      721 tacctcttta taattagtac ccaaaagttt aaataccgga agtaaagcaa aagagagatt
      781 ttcagtcaca ctaccaccgg cctgaaaact gtcaagttct cgcactccct gaacctttaa
      841 agtggataaa gaagcatcta tatcaacgat ggtaccgatc aaaccggatt ttatcaatgt
      901 aatcagatga ttaaaagcag ggcagtgagc tgttttgtta gcttccatga aagtcaatcc
      961 tttggatctg gcaagttcac aaagttgctg tgcctcggaa aaggatagtg tcaaaggagt
     1021 ttcgcataaa acgtgtttcc cacaatccaa aagttgttta acatagtcat aatgggttaa
     1081 atgtggagat gcaacataag cagcatctat atgtttacac aattcggaaa aagaacatga
     1141 cacatgggat ataccaaatt gctctgaaaa tgaagatgcg gactcctgat caggattata
     1201 aactgtagtt atgttaactc cattgacaaa agcaacctca ggaataaact tatgggctat
     1261 gcgccctgtg ccgatgatac caagacgaac acaactctca ttcctcaact gtgtactgga
     1321 aatcccctct gtacgatcta gataaacaac atcacaatac tctttcagat aatcaaaatg
     1381 gcctctccaa tcggaaccaa ttgcaaatac atcaatatta tagcgctgaa tatcatctat
     1441 cttttggccg acatactctt ctatgataat ttcgtcagcc aaccccgttc gacgaacact
     1501 ttcgatacgc tccattacat tattgcggac atttagctta ccccgatcca aatcaaaatt
     1561 atccgtagtc acaccaacaa tcaaataatc acctaacgat ttggcacgac gaagtaaatt
     1621 caaatgacct tgatggagca aatcatatgt accgtaagta ataacccgtt tcatcgaata
     1681 aattataatt gttcgatacg ataaatttcc tcagacaaac aaagcaaatc ctgcttatcc
     1741 tgtactccaa gatgagatac ccgaaaataa ttaggtgttc cccccggcat tatgtaaatc
     1801 tccctatcaa gtaattcttt gaaaagaata tcgccattac gattgataaa aaaaccggtg
     1861 atgcaattag acggcacttc agcaggaaca atccaattgt acttattaca taaagtacga
     1921 aaaaacaaag cacgttcacg aactcgggaa ataatgctgt ctactcctat ctgaacatta
     1981 cgtttcagtc gttcatgcaa ttgtaaaaaa atcgtagtag ccggactata aggggtctgc
     2041 ccgcgttgga gattttttaa attttcatta aaatcaaaat aataaccgga actggcaaag
     2101 tgcatatccg aaatattttg agaaagaatg acgaaagaaa gccctggagc tatattaagg
     2161 cctttttggc tgctggtaat gcagatatct attcccaaat cagacatatg cagaggatca
     2221 gccaaaaaag aactgattgc atcaacgacc aaagagacat gatatttttt acaaatatag
     2281 gagattttat ctaaattgaa catttgtcca gtagaggttt catgctgctg gcaaagaaac
     2341 acatctggat gcgataatgc aatcttggcc tcaagatctg agtaatctat atcttttgca
     2401 aaaggcactt catacaaatc aacatcaata tcataatagt cgcataaact tttccaacga
     2461 taaccaaaag aaccgccagc aacaacaaaa gctttatgct ttagagaaac ataattggtt
     2521 acaactgcat ccatcgcacc tgttccggaa gctgtataaa aaataacccg cccattaggg
     2581 caaccaatca aacgaagcaa catactctca caatcttgca ccaaagatga aaaagaggaa
     2641 gtacgcatgt agggaatggg aagagaagaa ataccaagga tatccgactc tatattacca
     2701 ggaaatacaa aagaattcat aaataactca aattttaaaa ctactaagct aatcgattta
     2761 caatattttt cacttctctt atcagctcct catctcccat ctgttcaaag cactccagca
     2821 gcaattgaca tttcaataca gaggctggta gtttttctaa aacagtcatt gaacgatcca
     2881 ataattcttg aacaacctgt tcattttcta aggagaaatt aaacagcatg gtatcgtaac
     2941 ctttgaacaa agtaacaaga atttccgcct cttcttcggg ggattttcct ttctgaagaa
     3001 gaagatcggc acacaagtta cggagttctt tatttaacgc agtaagttca ttcacataga
     3061 caggagtacc gtccccgcca tactccaaga gtttcttcac tacggaggac acagaattac
     3121 acagagaatt tttcatttta aaaaggaatg aattatgatt cgtcgattct ttttcggttt
     3181 ttatttatat agaaaaagta acttcagttt cagaagtaga tttacgccgt ctgaaccgat
     3241 atacttatgc ctttcttcaa ttaacattgt taacgtcttt tttagactgt ttggttcttg
     3301 tgcgtaaaca acaagccttt tgcatttaaa acactcgtta tttgcatcta aagaacaagc
     3361 tttaacactg tgttaaaacg aaacttttgt agacagaagg cttgtacttt gaaagcatta
     3421 cttttcaaac agttaagtgt taaattcgct ttttcctctc accgatagcc ttttcggtcg
     3481 aaagccggga tacttacttt tttgtcaact ataaatgagc acttgcactt ccgaaacctg
     3541 aagaagagta ataatatcca atagaattat atctaacgac gtaacggggc attacatata
     3601 ttgttatcac ccgttacata tattgttatc gccattacat ataatggtat tttctttaca
     3661 tatatacttt ttatttctct ttccggacgt agctagccgg aattgtaacc atagcgctac
     3721 cgaacatatc gatacgtact aaaatatgat atttattatt atagcggacc aattctcccc
     3781 gcaagccttg taaatcgccc ttggcaacta ctacacgagt acctttggga atggactctc
     3841 ctgtcaggat cacctgatcc tgggagtaat cgagcatata gcgaaaatca gccatttgcg
     3901 catcagggat acaggtagga gccccggtgg aacgatcacg aaggaaatcg tatacattca
     3961 gtgtacttcg gacggcagcc atttcctgac gggagatatg aacgaaaacc atacggggca
     4021 acaaaaggcg ctcacgctca atgcgttttc cttcacgctc tatgacacgg ttttgtacag
     4081 gaagaaaggt atctacctcc tgcaattgaa aataatcccg aactttacgt tctgagttag
     4141 ttcgtgtcag tacgacatac caatgtttat cgctatctgt tgtctccaag actacgttcg
     4201 taagaaaaag tttcagtaat gactaagaat gaaaatttgt taaaaacaag aacattcaaa
     4261 aaacatgcct tattttcagt aatttacaaa ttaagtttta tgataatcgg gtacagaaaa
     4321 agtattcgca ccggatttga atactatccg atacgttgaa ttattttatt ttaaacatat
     4381 atcggacata aagaaaagta tatttgtccg cctatatatt tacgggtgca aaggtaaaac
     4441 cttcttttga gtctccaaaa cttttcacag gttattttca tcataggaag ttatataact
     4501 gaatatcaaa gatataattt atctctttgc aaataaggaa agcagcaata tacataatac
     4561 taatgtggct cataaaagaa tgtggaaata agtggagagg caggctatgg agagtcttaa
     4621 cggtaacttg ataaacagac aactacgcac atcttgaatg taagagaaga attttacggc
     4681 agaacgcatc cagaatataa gcaattgatt atcaaacaat aatatcttaa taagagaact
     4741 gtaggaagtt aacattaaca gtacgttaat attaacttcg taattgcaag atattaattc
     4801 tttagagata cgaagttaat aagctattga taaggaggga aagcactttt acgggcatta
     4861 acattgttaa cgtattcgtt ggtaagagcg tcccggcatt ggttacaacc gcacagtttg
     4921 ccgatggctt accaggcaca gttcttcttt cttcgtccgg aatatggccg tatcggtaaa
     4981 accacttttg gaaagaatcg ccttcagttc atcacaggaa tgaatctcca tcccttcaac
     5041 aagtcccgtc caagccttat tggcaggatc gcttatctca caacagataa gaaacgatcc
     5101 accgggcttt aacacacgcg ccacttccgt aaaagcatgc tgcaggttac cccagaagta
     5161 gacagtctcg aaagcagtga ccgcatcgaa cgcataatca ggatagggaa gtcggtggac
     5221 tcctccctgc tcgataaagc agcgtgtacc gagatacttt ttattttttt tacgcgcaaa
     5281 ggtgacactc tccggtgaaa tatctatgcc atacgctttc ccttgcgggc aacgttgcaa
     5341 tatctgtagc aaattggcac caccaccgca accgatgtcg agtacactcc attccggttg
     5401 ccattgcaag catgacattc cccattgcgc caatgatgca tgtcctgtat tcatccccca
     5461 aagtatcatt cttccgaaaa aaccttcagg cttccggaaa ttctgtaaga tcctgcttac
     5521 aaagcctctc ttattcattt gtctgctgat ttaatatttc aggcaaaagt acagtttctg
     5581 cccaaacagg caatacccag aaatagggaa tttatttcct aaaagatatt tgcaggtatg
     5641 catctgcttc ccgttaaaat tatgacgaac agatgcccgg aggtgcgatg ctcttttcgt
     5701 tttcgtttca taaatattac ataaacatta caacataaca gattcattat caatatctat
     5761 taataataaa cattcatata ttcagtaaca ggtctgtaac actaccctcc tatttttgca
     5821 ccggaaaaca acaagcagat gttatgaaca atgtacagca agtaaaaact tattcgcaga
     5881 gaaaaatttc tgatttcctt ttcattcttt gggcaggcgg agcagcgctg ctctcctatt
     5941 cattggtata tgcactgaga aagccttata cagcagccgg atttgacgga cttgaagcgt
     6001 ttggaatgga ctacaaagtg gtagttacca tcgcgcaaat attaggatat gtactttcta
     6061 aattcatcgg aattaaatta atctccgaat taaaacggga aaaccggatg aagtttattc
     6121 tgatctccat aattctggct gaagcttcgt taatattgtt cggactgttg cccgcacctt
     6181 ataatatagg agccatgttt ctgaacggac tttcactggg atgtatgtgg ggaatcattt
     6241 ttagctttat cgagggaaga cgaatgacgg acattcttgc cagcttactc ggagtcagta
     6301 tggtcatcag ctcgggtacc gccaagtcgg ccggtttgta tgtcatggac actttgaaca
     6361 tcagcgaatt ctggatgcct gccctgatag gcggagttgc ccttcctcta cttgccttgt
     6421 tgggatatgc actcaaccgg cttccacagc caacagccga agacattgcc atgaaatcga
     6481 aacgggaaac actgaacggc aagcaacgat gggagctatt taagaatttc atgcctttcc
     6541 tcactctgct ctttatagcc aatgtggtac tgactatctt gagagatata aaggaggact
     6601 tcctggtaaa aattatcgat gtctctcaat actcttcgtg gatgtttgca caggtagaca
     6661 gcgtagtaac cctcattatt ctgataattt tcggattaat agtgttcgtc agaagcaact
     6721 tgaaagcact gtcgatatta ctgggattga tcattgccag catggtagtg atggcagtcg
     6781 tttcgtttgg ttacgaacaa ttgcagctga acgccatcgt ctggctattc atccagagcc
     6841 tgtgtctcta tctggctttt ctcactttcc agactatctt cttcgaccgt tttatcgctt
     6901 gcttcaaaat tcgaggtaac gtgggtttct tcattgctat gaatgatttt ctgggctata
     6961 cgggaacagt catagtattg gctgtcaaag aattcttttc accggacatt aactggacag
     7021 ctttctacaa tctgatggca ggatatgtgg gaataatctg tttcgttgct tttgtatgct
     7081 ctttcatcta cctgcaccaa cgctaccgca gggagaatta cggaaagaca ggggtattca
     7141 gaaaaaaaga agaagaaaaa gaagttcccg atttcgtata ttaattgcta tctttgtggg
     7201 tcaaaaaact taaaatgaaa gttcaccatg aagatttttc caagtagcag catcaagaaa
     7261 ctggatgctt acaccataga acatgaaccg attgcatcga tcgacctgat ggagcgggcc
     7321 gcacaggcac tgaccaaagc catcaccgaa cgctgggaca tcacaactcc cgtcacggta
     7381 tttgccggac cgggcaacaa tggcggagat gcccttgccg tggcccgaat gttggcggaa
     7441 aaggaataca aggtcgaagc ctatctgttt aacccgaaag gggaactgtc tgccgactgc
     7501 cagaccaaca aggagctggt agagatgatg gataatgtga agttcagcga agtaagcaca
     7561 cagtttgtac ctcctgccct gacgatggat catctggtag tggacggact ttttggttcg
     7621 ggacttaata agccgctaag tggcggtttt gcggcagtag tgaaatatat caatgcatcg
     7681 cctgccaccg tagtcgccat cgatatcccc tcgggactga tgggagaaga gaacacattt
     7741 aatgtaaaag ccaatatcat ccgtgcccaa ttgacattga gcctgcaatt gccgaaactg
     7801 gctttcctct ttgctgaaaa ttccgaattc gtaggcgaat ggaaactgtt ggatatcaac
     7861 ctcagtcgtg aagcgattga agagacggaa agcaattatg ccttattgga agcggaagaa
     7921 atacacgctc tgatcaaacc ccgtaacact ttctcacaca aaggaaactt tgggcatgct
     7981 ctgctgattg ccggttcgta cggcatggca ggcgcgtcga tactggcagc ccgcgcctgt
     8041 atgcgttcgg gtgtaggctt actgacagtc catgcaccca tacgtaacaa tgatatcctg
     8101 cagatttcgg ttccggaggc aattatcgaa tcggatgcca gcgataccta ctttgcctgc
     8161 cctacagata cggatgacta tcaggctgta ggaatcggtc cgggcatcgg acgctcggaa
     8221 gagaccgaag ctgcactgct tgaacaactc agtggttgcc agacacctct ggtactggat
     8281 gccgatgcac taaacatatt ggccaaccac cgccacgcac tgaccacatt gcccaaaggc
     8341 tctattctga ctccccatcc caaagaactg gaacgcatgg tgggcaaatg ccagaactca
     8401 tacgaacgac tgatgaaggc ctgtgaactg gcccgaaccg ccaaagtaca tatcatatta
     8461 aaaggagcct attcggcaat tatcaccccc tcgggcaagt gctatttcaa ctctacgggt
     8521 aatccgggta tggcaacagc cggaagcgga gatgtattga caggtgtcgt gctggctttg
     8581 ctcgcacagg gatatccggc tgaagaagct gccaaaatcg gtacttatgt acatggtctg
     8641 gcaggtgatt tcgcacgcaa aaagcaaggc gttatcagca tgacggcagg agacattatc
     8701 agtaatctgc cattggcttg gcgtctggta agcgaataaa agttaacaac ttatgatttt
     8761 ccaaataact tcattaactt tgttttttaa accagttaaa ataaaccgga aatgaaaaag
     8821 ctaattatac tgacagggct gttactctct acctcggctt atgcccagac cgaagttaca
     8881 gcgggagtta cccggggaaa agattacggt gtaacctatg cacttcctaa aacagcaatc
     8941 aatattgaag tcaaagtcaa taaagtgaca tatactccgg gagaattcag caagtatgcc
     9001 gaccgttatc tccggttgac cgatgtgtcg ggtgagcctc aggaatattg ggaactggtc
     9061 agcgtcaaag caaaatctgt cggtatcccc gatagcgaac atacctattt tgtcaagctg
     9121 aaagataaaa ctgtagctcc gctaatagaa ttgaccgaag atggtatcgt aaaatcaatc
     9181 aacgtaccgc tatctcctaa aaagtcggct ccgatgcaac ccgccacgac acagaaaaag
     9241 aagataaatc cacgtgattt tctgaccgaa gagattctga tggcaggttc tacagctaaa
     9301 atggcggagt tggttgccaa agagatttat aacattcgtg aaagtaaaaa tgccctggta
     9361 cgcggacagg cagacaacat gcccaaagat ggggagcaac tgaagattat gctcgccaac
     9421 ctggaagagc aagaggctgc catgaccgaa atgttctcgg gtaccttgaa taaagacgaa
     9481 aagatattca acatccgcct cactccggat aaggaaatgg acaacgaagt agccttccgc
     9541 ttttcgaaga agctgggcat agttgccaat aacgatcttg caggagagcc ggtttatatc
     9601 acgctgaaga atctgaaaac cgtcaacgta ccggaagacg atggcaaaaa gaaggtggac
     9661 ggcattgcct ataatgtgcc cggcaaagca caagtaacac taacggaggg gaaaaagcaa
     9721 tggtttaacg gagaacttcc tgtcacacaa ttcggtacta tcgaatatct ggctccggcg
     9781 cttttcaata agaaatcgac tgttcaggtt actttcaacc cggatacagg aggcttgatc
     9841 aaggtagata gagaagaagg agaataaagc ataatcaaaa actccggccg atcttaaatg
     9901 aagtgcaccc caaaagttca tgtttaactt ttagggtgca cttcattttt aaatcagccg
     9961 gagtctcttt attatattcc gatagtatat cgtaatgcaa tcagttctca atcactaatt
    10021 tcacaaatcc gtctttctgc aactgagtga tataagccgt aatacgtgat tcgtaatttt
    10081 cttcataatt gaagtgttct gccagctctt caataatccg gcgtacggtt ctctttccgt
    10141 caatcaactc ccatacggca gtgccatgat cttccagccg gacatgaata tccgcagaca
    10201 ttcctttagg caacaagaat cgccgcatcc actcgtattt aaaccggggg aaagcaatgg
    10261 taacggtacc atcgcttccc ttttcggccg taatattttc actacggaaa ggaattacat
    10321 ccagaagatt tattttctct ttcacgtctg ccatatactg ttattttttg atatttgctt
    10381 cctgcagtcc gtatcccttc ttcttgtctt ccgctttcaa cattaaagct acaatcagag
    10441 ccaaaacacc gaaacaagca aagatagcca taggcaaagt atagtcataa gtctgcgctc
    10501 catccacaac aggacctttg caataggtat tcaacaccca tccgatcaac agaggtaccc
    10561 ccatcaatcc ccagttctgc acccagaaaa tcaaagcata ggcagtaccc agttgtttct
    10621 ccggaataat tttcggaaca gaaggccaca tggccgaagg caccagtgaa aaagcaatac
    10681 ccagaacaat cataatcaca gtggcaaacc accatacgtt cagaatggga agcgcaaaca
    10741 aagtatgcac accaatcagc atgacggcac cgataatcat caacgtcgct cccttaccga
    10801 tacggtcata aagagtacca aacaacggag tcaggaagat ggtacctatc ggtagtaatc
    10861 ccggaatatt tccggccagc ttagggtcta cgttatactt ctgcaccatc aagtcggttg
    10921 catatttaat aaaggggaaa acagcagaat agaatagtac acacaataaa gcaatcagcc
    10981 agaagccttt attggtgaca atcagcataa cgtccttcat acggaacggt tcttccggtt
    11041 cttctccctg agcatctaaa gaagcgtcaa gtttcttatc ataaaaggta taaatgaaaa
    11101 aggcgatagt accgatgcac agcatgatca ggcacaacaa aataggcatc ggaatattgg
    11161 tatggaaact gccgctttca tccgtatagc cgaaataatc ggcaatggga acggtaagca
    11221 ccatagccaa agtggtaccg atacgtgcgg ttgccatctc aagtcccata gccaaagcca
    11281 tctctttacc tttaaaccat ttcacgataa tcttagagac ggtgataccg gcgatctcta
    11341 cgccgacacc aaagatagcg tatcctaaag ccgccagaaa gacctgagtc ttgaaaccca
    11401 taatcaaagc tccctcagga aaagttgtag agatagcata atattttagt ccacaaccca
    11461 acaccatcag tatacaagct cccataccgg tgaaacgaac tcccatctta tcgagaataa
    11521 taccaccgaa aatcaacatg agcaggaata cattgaacca tccgtaagca ctggtaaaga
    11581 atccgtagtc caaactatcc cagagaagct ctttctcgag cataggcttt aaaggggaca
    11641 ttacatcggt gaggaaatag ccgcaaagca tagtaaacgc gaccagagcg agcacactcc
    11701 aacgaagtgt tttggagtca ctcaatttgt ttttcaattg ttctgtcatt gtaatattta
    11761 aactcagaaa ttagtaaaag tgttattgcg aacaaaggta actaaatctg ccttgtatgc
    11821 ctaacaaaaa gatgcatttt acggcaaaaa ataagcgaag ctgcaagttt cggtttgaaa
    11881 ttgcagcttc gcttatcgtt tcttaaaaag aatctgttgt tagtttgccg gagtagctgg
    11941 agtttctgtg gcaggtgctt caaccggagc agcagcgtct gtcttcggtg cagtagtacc
    12001 tacgggcagg ttataagggt tggtctgctc ttcctgctgt gcctgttcca taatgacatc
    12061 ttgtgtttta gaagaagaag tcggaacgac atacgcagta gcaatgctca tcacaaccat
    12121 aaatgcagct aagccccaag ttgctttttc cagaaagtct gtagttttgc gtacacccat
    12181 aatctggtta gatgatgaga accctgaagc aagaccaccg ccttttgagt tctgaatcaa
    12241 cacaatgaag cacatcagta tggctgcaat aaccattaag ataactaata ataagtacat
    12301 tttgttattt tgatttagcg ttaataatca atttctctaa aaatctgatt tggtctgcaa
    12361 agtaagcatt tttttttgga tatttcaaac tta
//
