LOCUS       c00040_gnlPro..        13260 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADIJIICD_40.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:24:41
            Original ID  :: gnl|Prokka|ADIJIICD_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13260
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13260
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15:3260]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      16..3260
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13260
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13260
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(16..1008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 3.4e-119,
                     bitscore: 389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFIVSLVYFGLGA
                     LIVTATSVIACLFFEWAIGKFLLKKETTTICDGSAVITGVLLAFNLPSNLPVWIIILGA
                     LFAIGVGKMSFGGLGNNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTAATPL
                     ALMKQAIHGDVSAFGQLPDAWSLFIGNNGGCLGEVSAAALILGLLYMLWKRIITWHIPV
                     SILVTVFVFSGIMHLANPEAYVSPVIQLLSGGLMLGAIFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(1014..2351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_2"
                     /sec_met_domain="Fer4_7 (E-value: 5e-09, bitscore: 28.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.1e-16, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.9e-51, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.4e-31, bitscore: 98.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIVTAEVPAKAVILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEANGFVSAAIHSSVSGKVAKIDSIVDASGYAKPAIFIDVDGDE
                     WEESIDRNPELVKECELTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVAILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSVAQPSNFLARIGTPMQQLIDACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNRKEAKRGEVQNCIRCAKCVSACPMGLEPYLLSALAENTEFERM
                     ESERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(2388..3260)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36.6; E-value:
                     1.8e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_3"
                     /sec_met_domain="Fer4_7 (E-value: 4.5e-12, bitscore: 38.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-08, bitscore: 26.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 6.6e-09, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.1e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.2e-08, bitscore: 27.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.3e-10, bitscore: 32.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.7e-06, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAVLYVASKKFAVYEDPRIAQVSEVLP
                     QANCGGCGYPGCSGFADACVKAGSLEGKFCPVGGQPVMSQVASILGLDAGTAEPMVAVV
                     RCNGTCTNRPRTNMYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACVKACPKAIIELRAKGKKSRRVYVSCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDYNKCKSCRKCVEVCPQHTIIELNFPPRKPKEETPV
                     AEAAKTAEA"
     CDS             3441..3635
                     /locus_tag="ctg40_4"
                     /transl_table=11
                     /translation="MRKARRTACMPMEVAPIIVTSSPIFHADEVSVTSITFSLLSAEEQ
                     CPLTLQVEQADVWMILTKT"
     CDS             complement(3936..4340)
                     /locus_tag="ctg40_5"
                     /transl_table=11
                     /translation="MIKQDYLIRMIQEIISLIVNAILNKKKFRKDEWTEYDCLTRQILG
                     VSQEELLSMSLDEMIDCYEGDPNRMGKIELAAVTLLKVSDEVESDILQKSKLRQDGLSL
                     LKYVQKESSTFSIQRTNLIRMIEINESLKM"
     CDS             complement(4469..5902)
                     /locus_tag="ctg40_6"
                     /transl_table=11
                     /translation="MKTSHISTLAFAILFSSSVMAQKTNKPVSETVQSEVKADTLSETL
                     QQYLVLKLNLDGPKPKIDTVSILYNKYIGELEYLNDPSVPMRYIKTDPDYYRLFVPLTY
                     YNSPIAEYSTMHWKFKEPFVTPSLSSQLLPPYDTLQFSKAERASRLVNVALMDLYLNHP
                     NLVVNTEDHIMSRKLYHGDKKIEVPKTEVKSLFRADKVEDNVGEAEMVISKPNWWVTGG
                     NGSLQITQNYISDNWYKGGESNNAVMANLQLFANYNDREKVQFENLFEAKLGFNSSPSD
                     EYHKYLVNTDQLRLYSKLGIQAANNWYYTITGEFKTQFVKGYKANSEELVAAFLAPADV
                     IVSVGMDYKLKKKKFNLSVFMSPLTYNLRYIGNKNVDETKFGLDKGKCSKNDFGAQVQP
                     TISWTIIPSIVVDSRLNYLTNYKWVRVEWENTFNFVLNRYLSTKLFVHARFDDSAKPTT
                     GSSYFQLKELLSFGLNYKW"
     CDS             6286..7887
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_7"
                     /sec_met_domain="GATase (E-value: 3.7e-55, bitscore: 178.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGQNALCVHLTYVPFLSAAQELKTKPTQHSVKELQSLGVQPDILVLRTEHDLNTNL
                     RKKVALFCNVAENAVVQSIDASTIYEVPLLMQEQGLDETILQKMGLPVGERPPLGPWKD
                     FLNRRANATETVTIAMVGKYVELQDAYKSILESLSQAATYNDRKVKIEYVSSEHLTPDN
                     VDEQLGHVNGVVICPGFGSRGIEGKFVAAKYTREHNIPTFGICLGMQCMAIEFARNVLG
                     YADANSIEMDEKTKHNVIDIMEEQKAITNMGGTMRLGAYECVLKKDSKVYEAYKEEHIQ
                     ERHRHRYEFNNDYRKQFEEAGMKCVGINPESDLVEIVEIPTLKWYIGTQFHPEYSSTVL
                     HPHPLFVSFIKAAIDK"
     CDS             7936..9792
                     /locus_tag="ctg40_8"
                     /transl_table=11
                     /translation="MDKNTITGLVLIGILLVGFSFLSRPSEEQIAAQKRYYDSIAVVQQ
                     QEEALRAKTEAALANEKEETAADSASLFFNATKGKEAFTTIQNNLVEITLDNKGGRVYS
                     ALLKNYMGQDKKPVVLFNGSDASMNFNFYNKKGALQTKDFYFEAVNKTDSSVTMRLAAD
                     SASYIDFIYTLKPDNYLMSFVIKATGMDGKLAASTNYVDISWSQRARQIEKGYTYENRL
                     ADLTYKYTGDDVDNLSASKDDEKSVSERLDWIAFKNQFFSSVFIAEQDFEKTTVKSKME
                     KQGSGYIKDYSAEMSTFFDPTGKQPTDMYFYFGPNHYKTLTALDKGREEKWELNNLVYL
                     GWPLIRWINKWITINVFDWLSGWGLSMGIVLLLLTIMVKIVVFPATWKTYMSSAKMRVL
                     KPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSA
                     IELRQQSFLWADDLSTYDAFITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMQQQDTG
                     AQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFISTLISVVTMIILRRTTDENKLLT
                     ELEAKKKDPKQMKKTGFAARLEAMQKQQEQLAKERANKQNKK"
     CDS             9881..11212
                     /locus_tag="ctg40_9"
                     /transl_table=11
                     /translation="MTTKYTYKEIWIIAYPILISLIMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVYYLAIFMMAFGFSIGAQILIARRNGEQQYQAIGPIFYQGVYFLLSLAVVAFTL
                     SLCFSPHILKKVISSEHIYDASISYINWRVFGFFFSFVGVMFRAFFVGTTQTKTLTLNS
                     VVMVLSNVVFNYILIFGKFGAPQLGIAGAAIGSSLAEMVSVIFFVIYTWKRIDCKKYAL
                     NHLPGFRPEMLKRILNVSFWTMIQNFFSLSTWFMFFLFVEHLGERALAITNIIRNVSGI
                     PFMVTMAFAATCGSLVSNLIGAGEIKCVPGTIRQHIRIGYIFVLPLVILFALFPNLILS
                     IYTDIPDLREASIPSLWVLCSAYLILVPANVYFQAVSGTGNTRTALGLELCVLAIYLIY
                     ITYMILYLRVDVAVCWTTEHLYGICILFLSYLYIKKGNWQKKQI"
ORIGIN
        1 atgattctaa ctttttcatt tcttcttcgc tacctcccca aagcgttttg gtttgcaata
       61 cgtattgatt agcggagtga atgcattcat aatcagaata gcaaacgaca taccttccgg
      121 atatgcacca aacagacgga taacaaccgt cagcaaaccg atgcagacac cataaatcaa
      181 catacctttt ttactcatcg gagaggtgac atagtctgtt gccataaaga tagcacccag
      241 catcagacct cccgaaagca actggatcac cggagaaaca taagcttcgg gatttgccag
      301 atgcatgata ccggaaaata caaatacagt aaccagaatg gatacaggga tatgccatgt
      361 aatgattctc ttccataaca tataaagaag acccaaaatc agggcagcag cactcacttc
      421 acccagacat ccaccattgt taccaataaa cagactccag gcatcgggca gttgaccaaa
      481 agccgagaca tccccatgga tagcctgttt catcaatgcc aaaggagtgg cggcagtagt
      541 agcatcggta taagcagtta actgaccgac caccggccag gaagtcatct gtaccgggaa
      601 tgacaataac agaaacacac gccctgccag tgccgggtta aacggattgt tccccaagcc
      661 gccaaatgac atcttaccga caccaatagc aaacaaagca cctaaaataa taatccatac
      721 aggtaagtta gacggtagat tgaacgccag caacactccc gtgatgacag cagaaccgtc
      781 acaaatagta gtggtttctt tcttcagcaa gaacttaccg attgcccatt caaaaaacaa
      841 acaggctatc acagaagtag ctgtgacaat cagtgcaccc agtccgaaat atacgagcga
      901 aacgataaag gcaggaatca gcgcaatcag cacaccgtac atattctttt gtacgctgtc
      961 tccaccatga acgtgaggcg ataatgatac aattaattta ttttccatac ttattatttt
     1021 ttagcttgac gtgcacgaat catagctcct actttcccct tacccagacg acagtagtcg
     1081 agtaacggac gattggcagg acaagtgaac tggcaagagc cacactcgat acaatccatg
     1141 attctttctg attccattct ttcaaattct gtgttctcag ccaaagcgga aagcagatac
     1201 ggctccagtc ccatcgggca ggcactcaca cactttgcac aacgaatgca gttctgtact
     1261 tctccgcgtt ttgcctcttt ccggttcata attaaaattc cggaacttcc tttagcagtg
     1321 ggcacatcag tattaaccaa tgctttaccc atcatcggac caccgccaat tatttttccg
     1381 gtatcctccg gcaaaccgcc acaggcatcg atcaactgct gcatcggagt accaatacgc
     1441 gccaaaaagt tagaaggctg ggcaacagac ttaccggtca ccgtaatgac acgctcaaac
     1501 aaaggcttat ttttctgtac agcttgatat acggcaaatg cagtacctac attctgcaca
     1561 actgctcctg tagagatagg taatgcgccg cttgcaacct ggcgcttcgt aatagcatcg
     1621 attaactgct tctcaccccc ttgaggatat ttcactttca aaggaacaac ttcaataccg
     1681 gcataactgg atgcaacttt cgtcatcagt tggatagcat cgggtttatt gttttcgata
     1741 cctataaaag ccttattgac tttcaccgcc ttcatcagaa tagccacccc taccattacc
     1801 tcctcggcat gttccaacat cagttgatgg tcggctgtca agtaaggttc acactctaca
     1861 gcgttgataa tcacgcattc tgctttaaat gaaggaggcg gacaaagttt gacttgagtt
     1921 gggaaacaag ctcctcccaa accaacaatg cctgcatctg ctatcttctt cacaatctct
     1981 tccgaagtca attcgcactc ttttaccaat tcaggattac gatcgataga ctcttcccat
     2041 tcatccccgt ctacatcaat aaaaatagca ggtttagcat aaccgctcgc atcgacaata
     2101 gagtcaatct tagcgacttt accactgaca gaagagtgaa tggctgccga aacaaagcca
     2161 ttagcttcgg ctattttagt gcccaccttc accacatcac cttttgccac aataggctta
     2221 gcaggcgcac cgatatgctg ccccagcagt atcacagctt ttgccggaac ctctgccgta
     2281 acaataggtt gatgtgctga gagtttattt tcgtgtggat gaacaccacc aattgaaaat
     2341 gtcttcaaca tacaattctg tattttatct gtttattact cgttttttta agcttcggca
     2401 gttttggcag cttcggcaac aggcgtttcc tctttaggtt tacgaggagg gaaattcaac
     2461 tcgatgatag tgtgctgcgg acaaacttca acgcacttgc gacaagactt acatttattg
     2521 taatcgatgt aagcgagatt gttttcaagt gtaattgcct cgaacggaca agttttgaca
     2581 cacttaccac aaccgatgca acttaccgta caggctttgc gtgcgacagc ccctttgtct
     2641 ttgttgacac aagatacata tacacgacgc gatttcttac ctttggcacg aagctcgatt
     2701 atcgctttcg gacaggcttt tacacaagct ccgcaagccg tacacttttc ttcatccacc
     2761 tcaggaagtc ctgtttccgg attcatgtga atagcatcga actggcaggc agccacacag
     2821 tcgccacatc ccaaacatcc atagctacag ccggtctctc cgccataaag cgaagcagca
     2881 atagcacagc tctttgcacc gtcatacata tttgtacgcg gacggttcgt gcaggttccg
     2941 ttacatctaa ccactgcaac catcggttct gcagttccgg cgtccaatcc gagaatagag
     3001 gcaacctgag acatcacagg ctgtccaccc accggacaaa acttaccttc cagcgaaccg
     3061 gctttgacgc aagcatcggc aaatccgctg caacccggat aaccacatcc accgcagtta
     3121 gcctgaggca acacttcgga tacctgggca attcgtgggt cttcgtacac ggcaaatttc
     3181 ttagaagcaa catacaatac tgcagccaat acaagcgcaa tagctcccaa agaaatcact
     3241 gcaatcagaa tcaaattcat aatttttagt tatttattgg ttttatagta aaagaaaatt
     3301 tttgtttcaa ccgagttctg ttcaaccata ttatataata ataaggaata agcaccgcca
     3361 aagcagcaaa tgctccatat agttcactat gaagaactgt cttgaaaatg aaaaggccaa
     3421 agattaaaag aaagagagga atgagaaaag ccagaagaac cgcttgcatg cccatggagg
     3481 tggcaccaat aatcgtcacc tcgtccccta tcttccatgc agacgaagta tcggtaactt
     3541 caattacctt ctccttgcta tctgccgaag agcaatgtcc cttgacactg caagtcgagc
     3601 aagccgatgt ctggatgatc ctcacaaaaa cctgagaacc acttatgttt tccacaatac
     3661 cttgatgagt tattatatta gtcattttgc aaactgcaca ttacaaattg cggcaaattt
     3721 aagcataagt ttgaaaatta cgaagtattt gaatgttttt tatagtgcaa tatgaagtct
     3781 ttttaaagta atttttgctc tatcaatcgg gtatggaaac agaaaaagca ggcttttcac
     3841 ctgctttact aagaaaatgt tatcatcttc tgatattttt aaagaaatta gaaacaaaaa
     3901 ccaattcttt tatcactttc tgtttatttc cccttctaca ttttaagaga ttcattaatc
     3961 tcaatcatcc gaatcaaatt cgtccgctga attgaaaagg tactgctttc tttctgaaca
     4021 tattttagca aggaaagccc atcctgacgt aatttggact tttgcaaaat atcagattcc
     4081 acctcgtccg aaactttcaa caaagtcacg gccgccaatt ctatcttccc cattctatta
     4141 ggatctcctt cataacagtc aatcatttca tccaggctca tacttaacaa ttcctcttga
     4201 gaaactccta aaatctgtct cgtcaggcaa tcatattcag tccattcatc cttacggaac
     4261 ttctttttat tcaatatcgc atttacaatt aacgaaatga tttcctgaat catccgtatc
     4321 agatagtctt gtttaatcat aatatcctct ttttgaatta gaacttactt accacgggga
     4381 gaattaacct caccggaaag aagagagccg actgaagatt ccagtcggcc cctatttcat
     4441 atatttacat tatgtcaatt attcccgatt accatttata attcagacca aaacttagca
     4501 actccttcag ctggaaataa ctgctgccag tagtcggctt cgcactgtcg tcaaagcgtg
     4561 catgtacaaa tagtttagta gaaagataac ggttcaatac aaagttgaaa gtattctccc
     4621 actctacacg cacccattta tagttcgtca gatagttcaa acgggaatcg actacaatag
     4681 acggaataat agtccatgaa atagtaggtt gaacctgtgc accgaagtca ttcttcgagc
     4741 atttgccttt atccaatcca aacttggttt cgtccacgtt tttgttacct atataacgaa
     4801 ggttataagt caacggagac atgaatacag aaagattgaa ttttttcttt ttcaacttat
     4861 agtccatacc gacactgact atcacatctg caggagcaag gaaagcagct accaactctt
     4921 cactgttagc cttatatccc tttacgaact gggttttaaa ctctcctgta atagtatagt
     4981 accaattatt ggcagcctga atacctaatt tagaatacaa acgcaactgg tcggtattaa
     5041 ccaggtattt atgatattcg tctgacggag aagaattgaa tcctaattta gcttcgaaca
     5101 gattttcaaa ctgtactttc tcacggtcat tgtagttagc aaacaactgc agattggcca
     5161 ttacggcatt attgctctca cctcccttgt accagttgtc cgaaatatag ttctgggtaa
     5221 tctgaagcga accgttacct cctgtcaccc accaattggg cttggagatc accatttccg
     5281 cttcacccac attgtcttcc accttatccg cacggaacag gcttttcact tctgttttcg
     5341 ggacttcaat cttcttatcg ccatgataca acttacggct catgatatga tcttcggtat
     5401 taacgactaa attaggatgg ttcagatata gatccatcaa agcaacattc accagccggg
     5461 aagctctctc agctttagaa aactgcaatg tgtcatacgg cggcaataat tgcgaagaaa
     5521 gagagggagt aacaaaaggt tccttaaact tccaatgcat ggtagaatat tccgcgatgg
     5581 gagagttata ataagtcagc ggtacaaaca gtcggtagta atccggatcc gtcttaatat
     5641 aacgcatggg tacagaagga tcattaagat attccaactc tcctatatac ttattatata
     5701 agatggacac cgtatctatc ttaggcttcg gaccatccag attcagtttc aggacaaggt
     5761 actgttgaag cgtctcggaa agtgtatctg ctttcacttc actctgcact gtttcagaaa
     5821 ccggtttgtt cgtcttctgc gccatcactg acgaagaaaa caggatcgca aatgctaatg
     5881 ttgagatgtg actagtcttc atttttataa caaatttggg gcaaatttac attaaatagt
     5941 ttagattaca taaaatttgc tcgattttaa taggaataac ctatcaaatg aatctataca
     6001 acaattcagc tgttttattg gaacgtgcgt tatctctcag aataatacag atcgaactga
     6061 gaaccgcctt cccccggctc gatagtgcaa gttgaataaa ggcgtgctta tatgccggca
     6121 aacatgtgac tgtttgtcgt tcaaacattt cggtacccgg aattgcattt tttaataaat
     6181 ttgttttgta gaaagcatcc gttcttcccc atttttttgt aattttgcgg tttttaagat
     6241 tcaaatcaaa ggatttagaa acaaattatt aaaacagtta tagctgtggg agaaacaaag
     6301 tatattttcg tcaccggtgg tgttgcctct tctttaggaa aaggtatcat ttcatcttcc
     6361 atcggtaaat tgctgcaagc aagaggttat aaagtaacta tccagaagtt tgacccgtac
     6421 atcaacattg acccgggaac attgaaccct tatgaacacg gagaatgcta cgtgactgta
     6481 gacggccatg aagccgatct tgacttagga cactacgaac gtttcctggg catccagaca
     6541 acgaaggcca acaacatcac gacaggccgt atctataaga gcgtcatcga taaagaacgc
     6601 cgtggagatt atttggggaa aaccattcag gtgattcctc atatcaccga tgaaatcaaa
     6661 cgtaacgtca agttactggg taacaagtat aagttcgact ttgtaatcac agaaattggc
     6721 ggaacagtag gtgatatcga atctttgcct tatctggaaa gtattcgtca gttgaaatgg
     6781 gaactgggtc agaatgcctt atgtgtacac ctgacttatg tacctttcct gtccgccgcc
     6841 caagaattaa aaaccaaacc gactcaacat tccgtaaaag agttgcaatc actcggtgta
     6901 cagccggata tcctggtgct acgtaccgaa catgacctga ataccaactt gcgcaagaag
     6961 gtcgctctgt tctgtaatgt agccgaaaac gcagttgttc agtcaatcga cgcttcaact
     7021 atttatgaag tacctctgtt gatgcaagag caaggcctgg acgaaaccat actccaaaag
     7081 atgggtctgc ctgtaggcga acgtccgccg ttgggtcctt ggaaagactt cctgaaccgt
     7141 cgtgccaatg caactgaaac agtaaccatt gcaatggtag gtaaatatgt tgaattgcag
     7201 gatgcctaca aatctattct ggaatccttg tcacaagctg ctacctacaa tgaccgcaaa
     7261 gtaaaaatag aatatgtatc atccgaacat ctgactccgg acaatgtaga cgaacaattg
     7321 ggacatgtaa acggagtagt tatctgtccg ggattcggtt cacgcggtat cgaaggtaag
     7381 ttcgtagctg ccaaatacac ccgcgaacac aacattccga cattcggtat ctgtctgggt
     7441 atgcaatgta tggctatcga gtttgcccgt aatgtgttgg gttatgccga tgccaactcc
     7501 attgaaatgg atgaaaagac caagcacaac gtgatcgaca tcatggaaga gcagaaagcc
     7561 atcaccaata tgggaggtac catgcgtctg ggagcttacg aatgtgtatt gaagaaagac
     7621 tctaaggtat acgaagccta caaagaagaa cacattcagg agcgtcatcg ccaccgctac
     7681 gaattcaaca acgactatcg caaacaattc gaagaggccg gcatgaagtg tgtaggtatc
     7741 aaccccgagt ccgacttggt agaaattgta gagattccta cattgaaatg gtacatcgga
     7801 acacagttcc atccggaata cagcagtacc gtactacacc cgcatccgtt gttcgtgtcg
     7861 ttcatcaagg ctgcaatcga taagtaaaga tcgttatcgt atagattatt aatcattaat
     7921 cacttaaaaa agagaatgga taaaaacacc atcacaggcc tcgttttaat aggtatatta
     7981 ctggtaggat tcagttttct gagccgtccc agcgaggagc aaatagccgc tcaaaagcgg
     8041 tattatgact ctatagccgt ggtacagcag caagaagaag cactgagagc caaaaccgaa
     8101 gctgcgctgg ctaacgaaaa agaagaaaca gcagccgact cagcatcgct cttcttcaat
     8161 gccaccaaag gtaaagaggc gtttactact atccagaata atttggtaga aatcactctg
     8221 gataacaaag gcggccgtgt ttactctgcc ctgttgaaaa actacatggg acaggataag
     8281 aaaccggttg tgttgttcaa cggcagcgat gcttccatga acttcaactt ctataacaag
     8341 aagggggccc tccagacaaa agacttctat tttgaagcag tcaataagac agatagcagt
     8401 gtaacgatgc gtctagctgc cgacagtgcc agctatatcg atttcattta tacactgaaa
     8461 cctgataact acctgatgag ctttgtgatc aaagctacgg gaatggacgg aaaattggct
     8521 gccagcacaa actatgtgga catctcatgg tcacaacgtg cccgccagat cgaaaaggga
     8581 tatacttacg aaaaccgttt ggcagacctc acctacaaat acaccggtga tgatgtggat
     8641 aacctttcgg caagtaaaga cgacgaaaag tccgtttcgg aacgtctgga ctggatcgct
     8701 ttcaagaatc agttcttctc ttccgtattc atcgcagaac aggatttcga aaagactacg
     8761 gttaaatcga aaatggagaa acagggaagc ggttacataa aggactattc cgccgagatg
     8821 agtacgttct ttgatccgac cggcaaacaa cctaccgata tgtatttcta cttcggcccg
     8881 aaccactaca aaacgttgac tgcgttggat aagggacgtg aagagaaatg ggaacttaac
     8941 aacctggtat atctgggctg gccgctgatt cgttggatta acaaatggat caccatcaac
     9001 gtattcgact ggttgtccgg ctggggatta agtatgggta tcgttctgtt gttactcacc
     9061 atcatggtga aaatagtcgt tttcccggca acatggaaga cctatatgtc atcagccaaa
     9121 atgcgggtgc tgaaaccgaa aatcgatgaa atcaacaaga aataccccaa acaggaagat
     9181 gcgatgaaga aacagcagga agtgatggga ttgtacagcc agtacggtgt aagcccgatg
     9241 ggtggctgtc tgccgatgtt gttgcaattc cctatcctga tggcattgtt catgttcgta
     9301 ccgagtgcta tcgaacttcg tcagcagagt ttcctttggg cggatgactt gtcgacttat
     9361 gacgcattca tcactttccc gttccatatt ccattcttgg gtaatcacct cagtttgttc
     9421 tgcttgctga tgactgttac caacatcctg aatacgaagt acacaatgca acagcaggat
     9481 acgggtgccc agccgcaaat ggctgcgatg aagtggatga tgtacctgat gccgatcatg
     9541 ttcctcttcg tcttgaacga ctatccttcg ggattgaact attactactt tatttcgact
     9601 ctgatcagtg tagtaaccat gatcatactg cgccggacaa ctgacgaaaa caaattgctt
     9661 accgaactgg aagctaagaa gaaagatccg aaacagatga agaagaccgg atttgccgca
     9721 cgcctggaag ctatgcaaaa acaacaggaa caattggcaa aagaacgggc taataagcag
     9781 aataagaaat aagagataga aatcagctta aataccgaag agccggacaa gcagtgtatg
     9841 tttgtccggc tttcttttcc tttattgaac agattacaac atgactacta aatacacata
     9901 caaagaaata tggattatcg cctaccccat cctgatcagc ctgatcatgg aacagctgat
     9961 aggcatgacc gacactgctt ttctgggacg tgtgggcgaa gtcgaactgg gagcctcggc
    10021 cattgccggt gtatactatc tggctatttt tatgatggca ttcggattca gtataggtgc
    10081 acaaatcctg attgcccgtc gtaacggtga acagcaatac caggctatcg ggcccatctt
    10141 ttatcagggt gtctactttc tgctttcact cgcagtggta gcattcactc tttcgctgtg
    10201 cttctcaccg cacatactga aaaaggtcat tagctcggag catatatacg atgcgtccat
    10261 cagctacatc aactggaggg tcttcggctt tttcttctcc tttgtcggag taatgtttcg
    10321 tgcattcttc gtgggtacaa ctcagaccaa aaccctgaca ctgaactctg tggtcatggt
    10381 attatccaat gtggtgttca actacatact gattttcggt aagttcggtg ctccacagtt
    10441 aggtatcgcc ggagccgcca tcggttcgtc actggccgaa atggtttcgg tcatcttctt
    10501 cgtcatctac acctggaaac ggatagactg taaaaagtat gccttgaatc atctgcccgg
    10561 attccggccg gagatgctga aacggatcct gaacgtatcc ttttggacaa tgattcagaa
    10621 ctttttctca ctgtccactt ggttcatgtt cttcctattt gtcgaacact taggcgaacg
    10681 tgcactggcc ataaccaata tcatccgtaa cgtatcgggc atcccgttta tggtcaccat
    10741 ggcatttgca gctacttgcg gctccctggt gagtaacctg atcggtgcgg gcgaaatcaa
    10801 gtgtgttccc ggaacgatcc gccagcacat ccgtatcggt tatattttcg tgttgccgct
    10861 ggttatactc ttcgcactgt ttcctaacct gatattgagt atctatacgg atattcccga
    10921 tttgcgggag gcctccatcc cttctttatg ggtactatgc tccgcttatc tgatactcgt
    10981 acctgccaac gtctattttc aggcagtatc cggaacgggc aacacacgta cggcgttggg
    11041 attggaactc tgtgtactgg ccatttatct gatctatatc acctatatga ttctctatct
    11101 gagagtggat gtagccgtct gctggactac ggaacatctg tacggaatct gtatcctgtt
    11161 cctttcatac ctttatataa agaaaggaaa ctggcagaaa aagcagattt gacctgattt
    11221 ttgcttatct tcgcagcact attatggaag agaacacaag taaattacta attattaaaa
    11281 taactatgag acaagtaaac ctatttatta tgtcggcagc aatgatgtta gcatcttgtg
    11341 gtggaaccaa agatgcaggc aaaacagatc aggcgctgat cggtaaatcc gatatcaaga
    11401 tcgaaggaaa gcggatgact cccgaagcgc tttgggcgat gggacgtatc ggcggactgg
    11461 ccgtatcgcc tgacggaaag caaatagcct atactgtggc atattacagt gtccccgaga
    11521 acaagagcaa ccgggaagtt tttgtgatga acgcggatgg aacggataat cgacagatta
    11581 cccacactcc ttatcaggaa aatgaagtga cttgggcggc agacggaagc aagctgctct
    11641 tcctgagcaa tgacaacggc agcagccaac tgtatgaaat gaatccggac ggtagcggac
    11701 gcaagcagat ctccaagtat gacggagaca tcgagggata ttccatctca ccggacggta
    11761 aaaagatact cttcatcgct caagtgaaaa cagtaaagag cacggctgat aaataccccg
    11821 acctggataa agcgaccgga atcatcatca ccgacctgat gtataaacat tgggacgaat
    11881 gggtgaccac cgctccacat cctttcatcg ccgactttga tggcaaatca atctccaaca
    11941 tcatagatgt gctggaagga gaaccttacg aaagcccgat gaaaccttgg ggaggtatcg
    12001 aacaactggc ttggaatacg acttcggaca aggtggctta tacctgccgc aaaaaaacgg
    12061 gactggctta tgccatatct accaactcgg atatctatgt atatgacctg aataccaaga
    12121 aaacagtaaa catcaccgaa ggtatgatgg gttatgatac aaacccgcaa tattctccgg
    12181 atggaaaaag cattgcctgg caaagcatgg agcgcgacgg ttacgaagct gaccagaacc
    12241 gcctcttcgt catgaacctg gaaacgggcg agaaacgttt tgtaagtaaa gctttcgatt
    12301 cgaatgtaga tgcattcata tggagccggg atgccaagac gatctacttc accggtgtat
    12361 ggcatggcga gacacaaatt tattcactcg atctgtctaa cgattccgta cgccccgtca
    12421 cttcgggtat gtacgactac gaaggtgttg ccctctttgg agacaaactg attgccaaac
    12481 gccattcaat gagtatgggt gacgaaattt acgcaatagc tttggacgga caaaccacgc
    12541 aactgaccca agagaacaag caaatctatg accagatcga aatgggtaaa gtagaaggcc
    12601 gctggatgaa aacaactgac agcaaagaga tgctgacatg ggtcatctat ccgcctcaat
    12661 tcgatccgaa taagaagtac ccgacactgc tcttctgcga aggtggtcct cagagtccgg
    12721 taagccagtt ctggagttat cgttggaaca tgcagattat ggccgccaac ggttatatcg
    12781 tcgtagctcc gaatcgtcgc ggacttccgg gcttcggatt ggaatggaac gaggctatca
    12841 gcggtgatta cggtggtcaa tgtatgaagg attatttcac ggctatcgac gaaatggcca
    12901 aagagccgtt tgtggatagt gatcgtctgg gttgtgtagg tgccagcttc ggaggatttt
    12961 ctgtgtattg gttggccgga catcacgaca agcgcttcaa ggcatttatt gcccacgacg
    13021 gtatcttcaa tatggaaatg caatatctgg agacagaaga aaaatggttt gccaactggg
    13081 atatgggcgg cgcttactgg gaaaaacaga acccgacagc ccaacgtaca tttgccaatt
    13141 ctccccattt gtttgtcgaa aaatgggata ctccaattct ctgtatccac ggtgagaaag
    13201 actaccgcat ccttgccaac caggcaatgg ctgcattcga tgctgccgtg atgcgtggtg
//
