LOCUS       c00035_gnlPro..        15235 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FCBAOOCH_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:52:06
            Original ID  :: gnl|Prokka|FCBAOOCH_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15235
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15235
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5235]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5235
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15235
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15235
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..938
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     5.8e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_1"
                     /sec_met_domain="Fer4_7 (E-value: 4.5e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-08, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.3e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 4e-08, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 9.8e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLPQANCGG
                     CGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVVRCNGTC
                     MNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPETGLPEVD
                     EAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCIGCGKCV
                     KTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPAAPKPAA
                     VSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             963..2300
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_2"
                     /sec_met_domain="Fer4_10 (E-value: 4.7e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.8e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 8.3e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.8e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.6e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             2306..3298
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.7e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             3325..4041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAN"
     CDS             4077..4640
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.7e-69, bitscore:
                     224.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICSN
                     VVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLIVVNCIVL
                     GRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMPEEYGMLV
                     FVLAPGAFIALGYLIALINSFKKA"
     CDS             4663..5235
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 8.4e-63, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5460..6494
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 8.5e-52, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             6818..7117
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             7128..7490
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(7523..8353)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.9e-10,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2.5e-10,
                     bitscore: 32.2, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFILKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             8592..10151
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             10323..12785
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             12817..13551
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             13561..13806
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
ORIGIN
        1 ttgcagtgat ttcattggga gctatagcgc tcgtgctggc cgctattctt tatgtggctt
       61 ccaagaaatt tgccgtgtat gaagacccgc ggattgccca ggtgggagaa gtgcttcccc
      121 aggctaattg tggtggatgt ggctatcccg gttgtagcgg ctttgccgac gcttgcgtca
      181 aagccggttc gctggatggt aaattctgcc ccgtaggcgg acagcctgtc atggcacaaa
      241 ttgctgatat cctagggctt gcagccggag aagctgaacc gatggtagca gtggtaagat
      301 gtaacggaac gtgtatgaat cgtccgcgta ttaatcagta cgacggtgcg aagagttgcg
      361 ctattgccgc ttcgctctat ggtggggaaa cgggttgtag ttacggatgt ctggggtgtg
      421 gtgactgtgt ggctgcctgc cagttcgatg ccatccacat gaatcctgaa acaggacttc
      481 cggaagtgga tgaagcgaaa tgtaccgctt gcggtgcctg tgtgaaggct tgtccgaagg
      541 cgatcatcga aatccgtccg caaggaaaga aatcacgccg tgtgtatatc tcttgtgtga
      601 ataaagacaa gggagctgtg gcgcgcaagg cttgtacggt gagttgtatc ggctgtggca
      661 aatgcgtgaa gacttgtccg ttcgaagcta tcacgttgga gaataacttg gcttacatcg
      721 atccgcacaa gtgcaaatct tgccggaaat gtgtggaagt ctgtccgcag aataccatta
      781 tcgaattgaa tttcccgccg aggaaaccga aagaagaagc tccggctgct ccaaaaccgg
      841 ctgctgtttc taaagaagcg gtggaaactc ctgcaccggc ggcaaaagtg gaaactcctg
      901 ctgaaaaggc tacagaagct ccgaaagtaa cagaataata acagaataaa atacagaact
      961 gtatgttaaa gacattttca attggtggag ttcatccaca cgaaaataaa ttgtcggcac
     1021 atcaacctat tatcacagcg gaagttcctg caaaggctgt tattttgctg gggcagcaca
     1081 ttggtgcgcc tgcaaaaccg gttgtagcga aaggggatgt ggtaaaggta ggcactaaaa
     1141 ttgctgaacc tgccggcttt gtttcggcgg caattcactc ttcggtcagt ggtaaagtgg
     1201 cgaagattga tactattgtc gatgccagcg gttatgcgaa acctgctatc tttatcgatg
     1261 tggaaggcga cgaatgggaa gaaacaatcg accgtagcgc cacactggtg aaggaatgtg
     1321 aacttccggc agaagagatc gtgaagaaaa ttgccgatgc cggaatcgtt ggtctgggcg
     1381 gtgcttgttt ccctacacag gtgaaacttt gtcctcctcc ttcttttaaa gctgaatgtg
     1441 tgattatcaa tgccgtagaa tgtgaacctt atttgactgc cgaccatcag ctgatgctgg
     1501 aacacgcgga agaaatcatg gtaggtgttt ccatcctgat gaaagcggtg aaagtgaata
     1561 aggcatttat cggaatcgaa aataataagc ccgatgctat cgaactgatg actaaagtag
     1621 cttccagcta tgcaggcatc gaagtcgttc ccttgaaggt gaaatatccg caaggaggtg
     1681 aaaagcagct gatcgatgcg atcaccaaac gtcaggtggc gagcggtgcg ttgcctatct
     1741 ctacgggagc agtcgtgcag aacgtgggaa cggcgtttgc tgtttatgaa gctgtgcaga
     1801 agaataaacc gttgtttgaa cgggtgatta ccgtgacggg aaagtcggtt gcgaagccgt
     1861 ccaacttcct ggcccgtatc ggtacaccga tgaaacagtt gattgacgct tgcggtggtc
     1921 tgcccgaaga tacgggtaag gtgatcggtg gcggtccgat gatgggtaag gcgctcgtaa
     1981 atatcgaggt tcctactgcg aagggcagtt ccggcatcct gattatgaac cggaaggaag
     2041 ccaaacgcgg tgaagctcaa acctgcatcc gttgcgcgaa gtgcgtgagt gcctgtccga
     2101 tgggactgga accgtacttg ctcggagcct tgtctgaaaa cggagatttt gaaacaatgg
     2161 aaaaagaaag aatcatggat tgcatcgagt gcggctcttg ccagttcact tgtcctgcca
     2221 accgtccgct gctcgactat tgtcgtctgg gtaaaggcaa agtgggagct atgattcgtg
     2281 cacgtcaagc taaaaaataa cgaatatgga aaataaatta atcgtatcac tatcgcccca
     2341 cgttcatggc ggagacagcg tacagaaaaa tatgtatggc gtgctgattg cactgattcc
     2401 ggcttttctg gtgtctctct atttcttcgg actgggtgcc ctgattgtca cggctacttc
     2461 cgttgcggct tgtttgttct tcgaatgggc gatcggaaaa tatttaatga agaaaccgac
     2521 caccaccatc tgcgacggct ctgccatcat cacaggtgtg ttgctggcat ttaatttacc
     2581 gtctaacttg cctatctgga ttatcatcct cggtgcactg tttgctatcg gtgtaggcaa
     2641 aatgtctttc ggcggattgg gctgcaatcc tttcaacccg gcattggcag gccgcgtatt
     2701 cctgctgctt tctttcccgg tgcagatgac cagctggccg gtagtcggac agttgaccgc
     2761 ttatacggat gctaccaccg gtgccactcc gctggccttg atgaagcaag ccatttacgg
     2821 tgacactgcc gctttaagcc agattccgga cgcattgacc ttgctgatcg gacagaatgg
     2881 cggatgcttg ggtgaagtga gtgcactggc tctgctgatc ggactcgttt atatgctctg
     2941 gaagaaaatc attacctggc atattcctgt gtctatcctg gctactgtgt ttgtctttgc
     3001 aggcatcatg cacctggcag atccggaaaa atacgtttct ccggtattgc agttgctttc
     3061 cggtggtctg atgctgggtg ctgtctttat ggcaaccgac tatgtgactt ctccgatgag
     3121 taagaaaggg atgctgatct atggtgtatg tatcggtctg ctgacggtag ttatccgtct
     3181 gttcggcgcc tatcccgaag gtatgtcgtt cgccatcctg attatgaatg cgttcactcc
     3241 gctgattaac acctattgta aaccaaaacg ctttggggag gtagcgaaga agaaatgaaa
     3301 aagttagaat catctttaaa gaatatgttg ctggtactta cgggagtgac tgctatttcc
     3361 gttgcgttgc tggcttatgt aaatgaactg acaaaaggcc ccattgccga agcgaacgcg
     3421 aagacactga acgaggcctt gaaaaaggtt cttcccgaat ttaccaataa tccggtagcg
     3481 gaaagcgata cgatcttcag cgagaaagat ggaaagaaga atgttgactt tatcgtttat
     3541 ccggctaaga acggtgaaga acttgtagga accgctgtcg aagctaaatc aatgggattt
     3601 ggcggtgaac tgaaagtgct ggtaggcttt aatgccgaag gaaaaatcta taactactct
     3661 ctgttggctc acacggaaac tccgggattg ggctctaaag ccgacaaatg gttcggagcg
     3721 tatgatcctg cgaaaggaga aaaggcagta tctcacgaag agagtacgaa atctattttg
     3781 ggtatgaatc cgggtgaagc tccgttgacc gtcagcaaag atgggggagc agtggatgcc
     3841 atcacagctt ctaccattac ttcacgcgct ttcttgaatg ccgtgaatgc tgcttatcaa
     3901 gcctataagg ccgaaggcgg ggaagtgaac ggggtaaccg gtgcttctca aaaagcgaaa
     3961 ggcgcggacg cagatgctgc tgacgctgct acgggagcta cgatcaaagt tgaactaact
     4021 gattcagtca gtgctaatta agaaaggaga cagatatgaa taactttaaa gtaatgatga
     4081 acgggattat caaagagaat cctacgtttg tactcctgct cggtatgtgt cctacattgg
     4141 gtactacatc atcggctatc aatggtatgg gtatgggact ggctaccatg ttcgtattga
     4201 tctgctcgaa tgtggtgatc tctttaataa agaacctgat tccggacatg gtgcgtatcc
     4261 catcgtttat tgtggtgatc gcatccttcg tgaccttgct tcaaatggtg atgcaggctt
     4321 acgtgccggg actgtatgct acactcggtc ttttcattcc gttgattgta gtgaactgta
     4381 ttgtactggg acgtgccgaa gccttcgctg ccaagaataa cgcagttgct tctatgttcg
     4441 acggtatcgg tatggggctt ggctttacca tcgccctaac cttgctgggt gctgtccgcg
     4501 agtttttggg aaccggtaaa atcttcgatt tgaccatcat gccggaagaa tatggaatgt
     4561 tggtgtttgt attggctccg ggcgctttca tcgctttggg atacctcatt gcgttgatta
     4621 acagtttcaa gaaagcctaa ttcaattaaa taagaaaaga atatggaata tatattgata
     4681 tttatttcgg caatctttgt aaacaacatc gtgttgtcgc agttcctggg tatctgtccg
     4741 ttcctgggcg tatccaagaa ggtggaaact gcgatgggta tgagcgctgc ggttgctttc
     4801 gtgttgacca tcgctaccat cgtcactttc ctgattcaga agtttgtact ggatgttttc
     4861 ggactgggat acttgcagac gattacattc atcctggtga ttgccggatt ggtgcagatg
     4921 gtggaaatca tcctgaaaaa ggtatctccg gccctgtatc aggctttggg tgtgttcttg
     4981 ccgctgatta caacgaactg ttgtattctt ggtgtcgcta tcctggtgat tcagaaagac
     5041 tatgatctgc tgacaggtgt tgtgtacgcg ttttctacgg ctatcggctt cggtctggca
     5101 ctggtgcttt ttgccggatt gcgcgaacag atgagccttg tgaaaattcc gaaaggaatg
     5161 caaggaactc cgattgcttt gattaccgcc ggtttgcttg ctatggcatt catgggattc
     5221 tccggcgtgg tgtaaggatt tacagttgat gattaaatag gggattggaa gctctgctgt
     5281 gtggcgacat acaggttaga gtttccaatt cttttttata cctaaatgct accaaatcgt
     5341 accttaatta cttttcagca aataaatttg tggcagatta ttgcaatttc attttatttc
     5401 catacatttg taactcaaac aataataagc cgagaaacta accatttttt ataaagtata
     5461 tgaaagaaag aattttagta acaggcggga caggatacat tgggtctcat actgttgtag
     5521 aactacaaaa cagtggatat gaagtaatca tcatcgataa tttatcaaat tcaagtgccg
     5581 acgttgttga caatatagag aaagtttccg gtattcgccc agtttttgaa aagctggact
     5641 gtttggactt tgccggtctg gatgcagtat ttgcaaaata taaaggaatt aaggcaatca
     5701 ttcactttgc agctagcaaa gcagtaggag agtcggtaca aaaaccgttg ctttactacc
     5761 gtaataacct ggtttctttg attaaccttc tcgaactgat gccaaaacat ggagtagaag
     5821 gtattgtgtt ctcttcttct tgtacagtat acggtcagcc ggacgagctg ccggtaacgg
     5881 aaaaagctcc gatcaagaaa gcggaatcac cttatggaaa taccaaacag atcaatgaag
     5941 agattattcg tgatacggta gcttcaggtg ctccgatcaa tgcgatcatg ttgcgctatt
     6001 tcaacccgat tggcgcgcat cctactgcat tgcttggtga actgcctaac ggggttcctc
     6061 aaaacctgat tccatatctg acccagacag ccatcggtat ccgtgagaaa cttagcgtgt
     6121 ttggtgacga ttatgataca ccggacggtt cttgtatccg tgactttatc aatgtcgttg
     6181 acttggctaa agcacacgtg attgctatcc gtcgtatctt ggaaaagaaa caaaaagaaa
     6241 aagtagaagt atttaatatt ggtacaggac gtggtgtttc tgtattggaa ttaataaatg
     6301 gctttgaaaa agccactggt gtaaaattga attatcagat tgtcggacgt cgtgcaggtg
     6361 acattgaaaa agtttgggct aacccggatt ttgctaataa agagctgggt tggaaagccg
     6421 tagaaacttt agaagatact ttacgctctg catggaactg gcagctgaaa ctccgtgaaa
     6481 gagggattca ataaaagaga aacttgtttt aaataacata aaagtttaaa caaatcgtgc
     6541 atgcgatttg tttaattgat gctaatcgac ctgaagctgt ttatgagtat gcgaatatac
     6601 gtagatagta cttatgcctc cccggcatag acaggaaaga ttgcatagta gttttgtcgt
     6661 gttttatttt gtgtttgtgt tgtgacggta ctacgacgtg agtcgtggta ccgttttttg
     6721 gtacgcccag catggatgtt ctgttttata aaatatttag cactaattct tttgttatcc
     6781 aaaattattt tgtaattttg tatcaaatga ataagatatg agagtagtat cacataagaa
     6841 attgaaagat ttctacgaga cgaaagggtg tgaagattca cgtgttgctt tagaacgttg
     6901 gtatgatata gcggaaaaag cagaatggcg gaatttgtct gatataaaag cggattttct
     6961 atcgactgat tatgtgggca atcaacacta tgtttttaat atcagaggga acaactatcg
     7021 gctggtagtg gttgttaaat ttacggtggg atacattttt gtccgttggg tgggaactca
     7081 taaagagtat gataaaatag attgttcaac tatataatat aatagatatg actaaaataa
     7141 cgaaagaaca atacgaattt gcattggcaa gagtcgaaga acttctgcct ttggtggacg
     7201 acagcactcc tgcaaatgac aagagcatgg tggagctttc tgttatgtct gatatagtga
     7261 ttgcgtatga gaaggaacat tttcctatag aaaaaccaac cgtagcagaa ttgatagaat
     7321 tgtcccttga agaaaagggg atgacacaaa aacagcttgc cagtgaaata ggggttagcc
     7381 cttcacgcgt gaatgattat atttcgggtc gctcggaacc tactttaaaa atagctcgct
     7441 tgctttgccg ggtactcaat atacaccccg ctgccatgtt gggattttga aaaaatagtc
     7501 aaaacataat tgttagtgag atttatttgt ttaatgtacc tttgaagcag aatacatcag
     7561 ttccccaatc aatttccggt aagacgaatc cgggagcaaa cagcccgaat acggatgagc
     7621 cggagccgct catggatgcg tagattgctc cttgatgata gagttcttct ttgatttctc
     7681 caatgacggg atgttgcggg aatacacttg cttcgaaatc attgattaac gtatccttcc
     7741 attcttgtac aggacgctgg attgcctccc taaccggata tttcggacga tggggatgaa
     7801 tgtttgaaaa ggcttcccgg gtggaaacaa aaacattcgg ttttataatc atgatttggt
     7861 agccgtttaa tgaaagttcg accggggaga agatgtttcc aattccctcg gcaaatatcg
     7921 gtctgttttt gataaagaaa gcgcagtctg ctcccaaagt ggcagcgtat acttccaatt
     7981 gttcttcgga tactcccagc tgataatgat cgttgagcaa ctttagtatg aaagcggcat
     8041 ccgatgatcc tcctcccagt ccggctcctg aagggatgtg cttgtataag tggatttcga
     8101 taggagggag atgaaattcc ttatccatca ataaataggc ttttactacc agattgtctt
     8161 cagggttacc ggctatttcc attccatgtt ggtggagagt gaattttcgg tcagcgttag
     8221 gggaggtacg gatttccagt gcgtcttcca gagccaccgg atagaaaact gtttccagat
     8281 tgtggtatcc gtccgggcgt ttttccgtga tggaaagtcc caggtttatt ttgatattgg
     8341 gaaaagcaat catatttcta tttactattt tactatttac tatttacagt gcttcacatt
     8401 acaattaatc atagctggat aatgtgaatc gggagcaaag ttactaaaat cttcattttt
     8461 ccttattcat tcttcgtgat tatattctat ctttgtcgtc tcgactggaa gaattccgtg
     8521 ataaatgtga taatagagtc tgtccagtcg taaaataata aatagtaaat cgtaaaatag
     8581 taaatatctc gatggccgaa cagaaaagaa atacccgcaa ttcaaagtct actaaaatac
     8641 aaccggtaaa tgattatggt cgtattcagc cgcaggcgcc tgaactggaa gaagcagttt
     8701 tgggagcttt aatgattgaa aaggacgctt attcattggt gagtgaaatt cttcgtcccg
     8761 aatcatttta cgaacgccgg catcagttga tttattctgc tatcgtcgat cttgcggtga
     8821 accagaaacc ggtggatatt ctgactgtaa aggaacaact tagtaaacgc ggagacttgg
     8881 aagaggtggg aggtcccttc tatattactc aattgagtag taaggtggct tcatccgcac
     8941 atattgaata ccatgcccgt attattgcac agaaatcgct ggcgcgtgag ctgataacgt
     9001 ttacgagtaa tattcagagt aaagcgtttg atgaaacgtt ggatgtggac gacttgatgc
     9061 aggaagcgga aggtaagctt ttcgagatct cacagcagaa tatgaaaaaa gattatacgc
     9121 agatcaatcc ggtgattgac gaagcctata aactaattca gaaagctgcg gctcgaaccg
     9181 atggtttgag tggtctggag agtggtttca cgaaacttga taagatgact tcgggttggc
     9241 agaattccga ccttattatt atagctgccc gtcctgctat gggtaagact gctttcgttc
     9301 tttcaatggc taagaatatt gcggtggatt accggaaccc ggtggcgttg ttctctcttg
     9361 aaatgagtaa cgttcagttg gtgaaccgtt tgattgcgaa tgtctgcgag attccgagcg
     9421 agaaaatcaa aagcgggcag ttggcaaatt atgaatggca acaactggac tataaactga
     9481 agaatctgat ggatgcaccg ctttacgtgg atgatacgcc gtctctgtct gtgtttgaac
     9541 ttcgaaccaa agcgcgtcgt ttggtacgcg aacatggggt gcgaatcatc atcattgact
     9601 accttcagtt gatgaatgcg agtgggatgg cgtttggtag ccgtcaggaa gaggttagta
     9661 ccatttcccg ttcgttgaaa ggattggcga aagagttgag tattccgatt atcgcactgt
     9721 cacagttgaa tcgtggtgtg gaaagtcgtg aaggtattga cggtaaacga ccgcagttga
     9781 gtgaccttcg tgaatcggga gccatcgagc aggatgccga tatggtgtgc tttatccacc
     9841 gtccggaata ctataagata tttcaggatg atcgtggtaa tgacttgcgc ggtatggcgg
     9901 aaattgtaat cgccaagcat cgtaacggtg cggtaggcga ggtgttgctc cgctttaagg
     9961 gtgagtttac ccgtttctct aatccggagg acgatatggt gatcccgatg ccgggcgagc
    10021 ctgcaggagc tatgttagga tcgaaaatga atacaggtaa tgctggttcc atacctcctc
    10081 ccgcacctga ttttgcaccg cagacggaga atccattcgg agcaccggga gatggaccgt
    10141 taccatttta gttaatagtt gataactgat agtgaaaatg ctctgcgcaa catttcttct
    10201 atctgtatgt tattccgcat ggtaactatc aactataaac ttttttatct aaccttctcg
    10261 gtcaaccgaa aaatcttatt aactttgcaa atctttttga gaaacaataa aaaattaaat
    10321 atatgaatat ctcttataac tggctgaaag agtatgtcaa cttcgacctg acgcccgatg
    10381 aaacggctgc tgcgttgact tctatcggct tggaaacagg tggtgtagaa gaagtgcaaa
    10441 ccattaaagg tggtttggaa ggactggtga tcggtgaagt gctgacctgc acggaacatc
    10501 ctaattctga ccatttgcat attactactg ttaatctggg agacggtgaa ccggtacaga
    10561 ttgtttgtgg tgccccgaat gtggctgccg gacagaaagt ggtggtagct actttaggta
    10621 cgaaacttta tgacggtgac gaatgtttta ccatcaagaa atcaaaaatc cgtggggtgg
    10681 aatctactgg tatgatttgt gctgaagacg aaatcggtat cggtacggat catgcaggta
    10741 ttatcgtatt gccggaaaat gctgttccgg gtacgcttgc caaggattat tataatatca
    10801 agagcgacta tgtgcttgaa gtggacatta cgcctaaccg tgcggatgct tgctctcact
    10861 atggggtggc tcgtgacttg tacgcttatc tgattcagaa cggcaaacag gctactttgc
    10921 aacgtccgtc ggtagacggc tttaaagtgg aaaaccatga cttgaatatt gaagtgaagg
    10981 tggaaaacag cgaagcttgt ccgcattatg ccggtgttac ggtgaaaggt gtcactgtga
    11041 aggaaagccc ggaatggctg caaaacaaat tgcgtctgat cggggtgcgt cctattaata
    11101 atgtagtgga tattactaat tatatcgttc atgctttcgg tcagccgttg cactgcttcg
    11161 atgccggaaa gataaaaggc aatgaagtaa ttgtaaagac aatgccggaa ggaactccgt
    11221 tcgttacgct ggatgaggtg gaacgtaaat tgaacgaacg cgacctgatg atttgtaaca
    11281 aggaagaggc catgtgtatt gccggtgtat tcggcggact ggactccggt tctacggaag
    11341 ctacgacaga tgtattcatt gaaagtgctt atttccatcc tacatgggtg cgtaagacag
    11401 cccgccgtca tggcttgaat acggatgctt ctttccgttt cgaacgcggt atcgatccga
    11461 acagtgtgat atattgcttg aaactggctg ctttgatggt taaagaactg gctggcggta
    11521 cgatttcttc tgaaataaaa gacgtgttca ctactcctgc acccgatttt atagttgatc
    11581 tggcttatga gaaagtacat tctttggtag gaaaagtaat tccggtagag acgatcaaga
    11641 gcattgtgac cagcctggaa atgaagatca ctaatgaaac ggcggaaggg ctgacattag
    11701 ctgttcctcc ttatcgtgta gacgtgcagc gtgattgtga cgtgattgaa gatattcttc
    11761 gtatctacgg atataacaat gttgaaatcc cgactacact gaactccagc ctgactacca
    11821 aaggtgaaca tgataaatcg aataaattgc agaacctgat tgcagagcaa ttggtgggct
    11881 gcggatttaa tgagatcctg aacaactcat tgacgcgtgc tgcttattat gatggtatgg
    11941 agacttatcc gtccaaccat ctagtgatgt tattgaatcc gttgagtgcg gatttgaacg
    12001 ctatgcgtca gactttgctg ttcggtggac tggaaagtat tgctcataat gcaaatcgta
    12061 agaatgctga tttgaagttc ttcgaattcg gtaattgcta tcatttcgat gctgacaaga
    12121 agaatgaaga gaaggtattg gctccttact cggaagatta tcacttgggc ttgtgggtaa
    12181 ccggtaagaa ggtttccaat tcatgggcac atgcagatga gaacagttcg gtatatgaat
    12241 tgaaggctta tgtagaaaat atattgaagc gtctgggact ggatttgcac aatctggttg
    12301 tcggtaatct gacggacgat atttttgctg ccgcactttc tatcaatacg aagggtggta
    12361 agcgtcttgc ttccttcggt atcgtgacta agaagctgtt gaaagcattt gatatcgaca
    12421 atgaagtgta ttttgccgac ttgaactgga aggaactgat gaaagctatc cgttctgtga
    12481 agatcagcta caaggaaatc tccaagttcc ctgctgtgaa acgtgacctg gcattgttgc
    12541 ttgacaagaa tgtgcagttt gccgaaatcg aaaagattgc ttacgaaaca gagaagaagc
    12601 tgttgaaaga agtggaactc ttcgacgtgt acgaaggtaa gaatctggaa gcaggcaaga
    12661 agtcgtatgc ggtgagcttc ctgcttcagg atgagagcca gactttgaat gataagatga
    12721 ttgataagat catgtcgaaa ctggtgaaga acttggaaga taagctgggt gccaaactta
    12781 gataaactta aaatttcaat ctaaaaatat aaaccaatgg gaagagcatt tgaatataga
    12841 aaggccgcta aactgaaaag atggggccac atggctaaaa catttacaag actgggtaaa
    12901 caaatcgcga tagctgtaaa ggcaggcggt ccggaacctg aaaataaccc gactttgcgt
    12961 tcggtgatcg ctacttgtaa gcgtgaaaat atgccgaagg ataatattga acgtgctatc
    13021 aaaaacgcaa tgggtaaaga ccagagcgac tacaagagca tgacttacga aggatacggt
    13081 cctcacggta ttgctgtatt tgtggatacg ctgacagata acacaacccg tacggtggct
    13141 gacgttcgtt cggtatttaa taagtttggc ggtaatctcg gtacaatggg atctctcgcg
    13201 ttcctgttcg accacaaatg tgtattcact ttcaagaaga aagacggatt ggatatggaa
    13261 gaactgattc tggatctgat cgattatgat gtggaggatg aatacgaaga ggatgatgaa
    13321 gaaggaacaa tcactatcta tggtaatccc aagagctatg ccgctattca gaaacacctg
    13381 gaggagtgtg gctttgaaga tgtcggtgga gacttcactt atatcccgaa cgacatgaaa
    13441 gaggtgactc cggaacagcg cgaaacattg gataagatga tcgaacgttt agaagaattt
    13501 gacgacgtgc agactgttta taccaatatg cagccggaag agggagaata agacaaggtt
    13561 atggaatatg tgtatagaac ccagggaact tgtagcacca acatcgaact gaatgtggaa
    13621 gatggagtgg tgaaagaagt tgctttttgg ggaggatgta atggtaacct tcaaggtatt
    13681 tcccgccttg tgagaggaat gaaggtagcg gatgttatcg caaaacttga aggagtgcat
    13741 tgtggtggca gaccgacttc atgtcctgac caattgtgtc gtgcattaca tgagatggga
    13801 tattaatcga cttcttttat ttttgtaaaa tttgatattt ttcaagacct tcggcaattt
    13861 attttgtcga gggtcttttt tttgtgggaa tccatagggg ggggatccgg gtgttgttta
    13921 cttacttgtc ggtattttga actaaaattg accttcactc gttatttata agtatatttg
    13981 taaggttaaa actattatgc aaaaatgaag aatatttttc aagacttaaa acgcaaagat
    14041 cataaacgct atctgggtgg actggatgtt tttaaatata ttggtccggg gcttctagtt
    14101 acggtaggat ttattgatcc gggaaactgg gcttctaact tcgccgccgg ttccgaattt
    14161 ggctattcct tactttgggt ggttacattg tccactatta tgctgattgt gcttcagcac
    14221 aacgttgccc acctggggat tgttaccgga ctttgccttt cggaggcggc cactaaatac
    14281 actcccaaat gggtgtcgcg acctattctt ggtacggcgg tactggcgtc gatttctact
    14341 tctttagcgg aaattctggg aggtgccatt gcgttggaaa tgctctttga tattcctatt
    14401 atatggggag ctgtgttgac tacgcttttt gtctctatca tgcttttcac taattcgtat
    14461 aaaaagatag agcgttccat cattgcattt gtctctgtta tcgggctttc gtttatctat
    14521 gaactgtttc tggtggaaat agactggccg gctgcgacag cagggtgggt gactccttct
    14581 tttccgaaag gaagtatgct gattatcatg agtgtgttgg gagcggtagt gatgcctcat
    14641 aatctgtttc ttcattcgga ggtgatacag agtcacgaat ataataagaa agatgatgct
    14701 tctattaaga aggtcttgaa atatgagttg tttgatactc ttttctcaat gattgtcggc
    14761 tgggcgatta acagtgccat gattcttctg gctgccgcta ctttctttaa aagcggtatt
    14821 caggtagagg aactgcaaca ggctaagtca ttgctcgaac ctttgttggg aagtaatgct
    14881 gccatcgtat ttgcactggc attgctgatg gcgggtattt catccaccat tacgagcgga
    14941 atggcggcag gttccatctt tgcgggtatt ttcggtgaat cgtatcatat caaagacagc
    15001 cactcgcagg taggagtcct tttatctctg ggaattgcct tattgctgat tttctttatt
    15061 ggagatcctt tcaaaggatt gattatttcg cagatgatac ttagtattca attacctttc
    15121 acggtatttt tgcaggtggg actgacgtct tcccgaaagg tgatgggaga ttatgtcaat
    15181 agtcgttgga gcacgtttgt gttgtattcg attgccatta ttgtttcggt actga
//
