LOCUS       gnlProkkaLAJMMHKH_33    5569 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAJMMHKH_33.
ACCESSION   gnlProkkaLAJMMHKH_33
VERSION     gnlProkkaLAJMMHKH_33
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:11:24
            Original ID  :: gnl|Prokka|LAJMMHKH_33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5569
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5569
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2:4249]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..4249
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5569
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5569
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..1085)
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 5.9e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_ctg33_1_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.6; E-value:
                     1.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_1"
                     /sec_met_domain="Aminotran_5 (E-value: 3.7e-32, bitscore:
                     100.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMRE"
     aSDomain        complement(207..995)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg33_1_Aminotran_5.1"
                     /evalue="5.90E-34"
                     /label="ctg33_1_Aminotran_5.1"
                     /locus_tag="ctg33_1"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             complement(1082..2218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_2"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-23, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(2230..3531)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_3"
                     /sec_met_domain="CTP_transf_like (E-value: 6.4e-13,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.6e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.3e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(3551..4249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.8e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(4263..5567)
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MVQRTTRMIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
ORIGIN
        1 gcctccctca tcacctcaaa gaacctctca atatcctcca catcaatctc tcccaacgca
       61 caaagccgga atgtattcgt tgtggaaatc ttacccgggt agatcgtaaa gccacgttca
      121 tagcagtaat catgaacctt atcaaaatcc cagaggggat catcaggata caatacagaa
      181 acaacaagac ccgactgcca ttcacgtttg atcgcatact gaagaccaag ctcttgcaaa
      241 cctttatgga tggcttcaaa gaccctcttg tgacgggcga atttagcctc ttcacctact
      301 gcaaaatatt catcaagagc ctgacgggca gcgtaaacgg tttgaacagg aggagtaaaa
      361 tgcatctcac ccgtcttctc aaagtaatcg tattgtaaat agaggttaca atagtaggag
      421 cgtttcggat aatcccttga agcacgtatc agggattcat cacctatgat aaaggaaaga
      481 cccgtcatgg cctgaaggcc tttctgagcc gaagccatac aaaagtcaac attatccttc
      541 ccgatatcaa aaggaatcat acccagggag gaagtggtgt cgacaacaaa aacggcaccg
      601 tgcgaatggg ctatttttcc gatctcacgg atggggttca agatacccgt acccgtttca
      661 tggtgcgtgg tatagaccaa agcgatgtcc ggattgtcgg aaagcgtctt ttcgattacc
      721 gacaggtcgg gaagttcgta aacggaaaac ttcaaatcga tatggggaag accgtaatat
      781 tcgcagactt ccaccgcacg ggtgctatag gcaccgttat tgacaaccag aactttctta
      841 tccgcaggaa gaagagagtt caggcagata tcgatattga tcgtacccga gccgcaaaac
      901 aggacggccg tatgtttgga gaggtctcca tgcgcaacgc ggaccaggtc gtcacgtaac
      961 tgtttcatca tacccgcaaa ctctttctca cgcggacaga tatcgggaac aacctgcgcc
     1021 agctttaccg tatccgtcgt ggtggcggga cccggattca aaaggatctt tctttcgata
     1081 ttcatgaatg cgtatctttt aaaaatgcca taaaatgctc tttattctct accggagtag
     1141 tcgtagggcg acccagatca tcacgtgaat cgatccggac cttaatttca agaagaaccg
     1201 ggccggacag gccggacagc ttctcaagcg cacacgaaag cccttccttg tcggaggcag
     1261 tcagtacatg cgcataaccg caacctttcg ctatcgaggc gatatccaga cggaaaccga
     1321 gcgtgggttg accgccgaca gattcatgcg caccgttgtt gaaaaggacg tgcctgtaat
     1381 tcttgggaga aagatcgccg atattgctga cagcacccat gtgcatgata aaggcaccgt
     1441 caccgtcaag acagtagaca cggcggtcag gcttctcaag ggcaatcccc agggcaatgg
     1501 aagaactgtg acccatggaa cccacagtta ggaaatccct tgcgtgcccc tgccctttcg
     1561 attcacggta ctcgaaaagc tcacgggaga gcttgcccgt ggtggaaacc acaatgtcat
     1621 tgtccccgag gtggtcgaca acctgcatta gcgcctcctc gcgggacaga ggatagtcat
     1681 tcaaggcttc ctgacgcaat ttatattttc caaacgtatc tttacggatg acaatcgcat
     1741 ggggaatcga ccggctcttc gccgagacaa ccgcgtcatg gatctgcgcc agggcctcgt
     1801 cttcatccgt atccagaatt ataaaaggaa ttttcatggc tttcagaaga tcaagggtaa
     1861 cctcgccctg cttcttatgc tggggttcgt cttttgtgcc gggctcaccg cgccagccga
     1921 ccagcaaaag aagaggaagg ctgtacactt tctcgtccgc aagggacaag aggggattca
     1981 ccgtatttcc cagaccggag ttctgcatat aaaccaaagg aacgttgcca gaagccatat
     2041 aataaccgca ggcaatgccc accgcggaac cttcattggc ggcgatgata tgcttaccac
     2101 gcggagcatg atccgtgata taggcgcaaa tattcttcaa aagggaatcg ggaacacccg
     2161 taaagaagtc aacaccgtga tgaaggaacg tatcgtatat cttttctaca cttaccataa
     2221 ccgtctgatt tatttagtgc ccggaatcaa ttccagaatt tccttgatag gcatacaaag
     2281 cggacggacc tcctcggcgc gctcgttttc aaggatggtc ctggccacgt tcatcatggc
     2341 cgggtaagcg gcacggagaa ggtggttggc gtaaatgact acgttggcac cccattcgtg
     2401 aagttcggat tcgtgcacat ggtcataagt cgtcggaaca acgacaatgg gaacatgggc
     2461 gtattctttg cggaaagtcc ggcagaactc acggatatcc tcacccgact tatccttgct
     2521 gtggatcatg atgccgtccg cacccgcctg tacataggca taagcacgtt cgagggcgtc
     2581 actcatgggt ttgccggcaa taaggctttc gatacgcgca atgatcataa agtcaccggt
     2641 gacctgggca ttcttccctg ctctgatctt atcgcagaaa ccctcgatac tatcctgagt
     2701 ctggatagcg tcagtaccaa aaagggaatt cttcttcaga ccgactttat cttcaatgat
     2761 tactgcagaa atgccatgac gttccagagt gcgcacagta aagacaaagt gttcgatctt
     2821 gccacccgtg tctccatcaa aaataatagg cttggtggta cattcaagga tattgttcag
     2881 gtcctgtaaa cgggtggtaa ggtcgaccgc ttcaatatcc ggtttaccct tactcgtgga
     2941 gtcggtcagg ctgctggacc acatgccgtc aaagacctcg cgcttatccc ccttctggac
     3001 ttcaagattc tcaataatca gaccgcaaag accgtcgtga gcctccagga tacggaccac
     3061 aggcttggcc tggatcaggc ggcggaggga cttaagacgt acgtcagggg tagtcccgat
     3121 cgccttgata tccttgtcga gcgaggagga gttgatgccc cgggtataag ggatctcgat
     3181 taccttgccc ccctgggcgt tcatcacctc aaaaacctgt tcgcgcacct cgcgcaacgg
     3241 gcccgttttc cagtcgtcgc cgtggatgat atagtcaggc ttgagttttt ccagattcgg
     3301 aacatagctc cagtcctcct ggggaacaac ctcaaaaacc cccttgatat tctcaacaac
     3361 ctccttacgc tgatcatagg taaggtaagg gaggcgtttg tgttcggcga tggccttgtc
     3421 cgtcagcaga ccgacgatga catcaccgta tttagtagct tcatgaataa tatggatcag
     3481 ccccggatgc atgatatccg cggtcatacc gacataaatt ttcttgttca tatatggaaa
     3541 agatttgttt ttaacaatag cggatgatgt gctcctcggc atacgaaagg tcggcttcat
     3601 catcgatttc ataccattta agaccctcca ccctgagcac acggacaggg gaaacggaac
     3661 gggacatgcg gagcagttcg tattcgtaac ccagtttagg ctgggactcc aggatggtcg
     3721 cataatcggc gcacatccgg cggtagaaag tattggaaag tttatggata ccgaccagct
     3781 cgccttttgc ctcaagggcg ttcttgtcta ccgaacagga agtaaggatg tgattgcggt
     3841 catattccac ataatactga tcctggaact tggtcagaga agagacaagc atcacatccg
     3901 ggaattcgtc atccagcagc gaaaggatgg ccttgcgttc aaaaacaagg tccgattcaa
     3961 gcagcaggaa actgtcatcg cctatcacgt cacgcgtatt gtacagagtg tacatactgt
     4021 tagtatcggc ataacgggga ctgaaacagg tctctatctg ggggaaatcc gcctgaaggg
     4081 cttcataagc ctctttttta taacccgtac cgaggatgat acgttcgata ccgcaggaaa
     4141 gaagggtttc gatagagcgg ataatcatag gttttccacc aacctccaca aaacctttgg
     4201 gcacaagctc ggtataatgc ccgaagcggg taccaagacc ggcagccatg atcattgctg
     4261 ttttaatcat gaatttcaga gggaattaat ataagtgaat tcaattgttg cttgaaataa
     4321 cagtaaatcg caaaaatcga caggacagaa acaaatcctg aaaaaagggc agtacgcatt
     4381 agcatgacag tccaggaaat gtcagcagaa acgaagttct tgaccataaa cacacccgta
     4441 gtgcccagat agccgaaaga atcggccaaa taaataataa aaacagccgt actaaccacc
     4501 ctaagggaag caatcagacg ttctatcagg taagtgaaag gaatataccc catatacaga
     4561 ccaagaccgg aaagaatcat ccaccaaata ggagaaagaa aaccgtacac ataaagcaat
     4621 gtggaaaaaa ccattaagga accgcctgtg acggcaatgc aataaatgat attaagagcc
     4681 aaacggttat tacggacaaa cacaatcagg aacatcagta caaggacaaa aacggcaatg
     4741 ggaacctctg tctgagtaaa gatcattgca ccctcaatat ggagctcctt ccaaatatcg
     4801 gcagcgaaag agtcacgaag ctcacggaac acggtcaggg caccgtaaaa aacaaccagc
     4861 atgcagattc cccagaagaa ttgcctcaaa aatttacgcc tgtctttacc atccatcgga
     4921 gcacgtttgg tacgctgtat gatatcttgc tcattgggag ccggaatctg attgagaagc
     4981 cagctgcaaa gcaacataac agggtatacc aacaaacctg tggtaaaagg catccaatat
     5041 tccgacacat gcaaattatc catcacgaat tgtcccaagg ttttcaccaa accggaagag
     5101 actatcaaag caacgctcag cccgacattc aatatttcac tgatacgacg cccttcgata
     5161 tagctaaaaa tgacacccca gatcataccc aggggaagac cgctcagaaa aatagaacac
     5221 accttcaaag gaaccggaag aagtgcaaaa cccaacaaag caacttcgga aaaagtaagc
     5281 agccctatta tataatagat gcggtgaccc gctttcatcg aaggcaaaat acgaacaccg
     5341 atgaacttgg aaagggcgta gccgataatc tcagaaagga catacagaat tttgacatcg
     5401 aatccccaaa gaatctcacc ttcataaatg gctgcggtaa atggcttacg gtaggcatag
     5461 gcacaagtat aaaccagaaa aatcaaaacg ctggcataga gagccaaaac gtaaagggga
     5521 gaacgggaaa gaaaggaacg aatcattcgt gtagttcgct gtacggata
//
