LOCUS       c00008_gnlPro..        11354 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMMAFHEK_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 19:51:38
            Original ID  :: gnl|Prokka|HMMAFHEK_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11354
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11354
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4753]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4753
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..11354
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11354
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..709
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 39.1; E-value:
                     2.9e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Fer4_7 (E-value: 5.1e-13, bitscore: 39.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.8e-09, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.7e-09, bitscore: 26.0,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.6e-09, bitscore: 27.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 3.7e-09, bitscore: 26.7,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-06, bitscore: 17.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAV
                     VRCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPE
                     TGLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSC
                     IGCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEA
                     PKTVAAEAPKVTE"
     CDS             734..2065
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="SLBB (E-value: 6.4e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.2e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETT
                     EKYVWRADRTDSGFSGVALFLRPGGSDCHGYFGSSLFILRMGDR"
     CDS             2073..2846
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 3e-99, bitscore:
                     321.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGALFAIGVGK
                     MSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPLALMKQAIH
                     GDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPVSIIVTVFV
                     FAGIMHMVDPEKYVSPVLQLFSGGLMLGAVFMATDYVTSPMSKKGMLIYGVCIGLLTVV
                     IRLFGAYPEGMSFAILIMNAFTPLINTYCKXXXXK"
     CDS             2843..3556
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="FMN_bind (E-value: 8.5e-24, bitscore:
                     73.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLESSLKNMLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTL
                     NEALKKVLPEYTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGG
                     ELKVLVGFDAEGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILG
                     MNPGETPLAVTKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEP
                     AAAPEGEEAANDTNN"
     CDS             3592..4158
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 9.9e-71, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             4181..4753
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.1e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5012..6046
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 4.1e-53, bitscore:
                     170.4, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDYANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(6279..7103)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.1e-10,
                     bitscore: 31.4, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.5e-10,
                     bitscore: 30.9, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLCPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIKNAPTFAEGIGNIFSPIPLSLK
                     GYKILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPVNEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQGAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFCFKGRL"
     CDS             7302..8855
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             complement(8844..9038)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MVGDKVAKNKGVFFVIFATYPHQNTTRLYSIKNNRPLDWSKSSGY
                     FHLTKRSFLFNPNERFLER"
     CDS             9178..11352
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYPSNHLVMLLNPLSADLNCMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFDADKKNPEKVLATYSEDYHLGLWVTGKKVANSWAHPDENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFATALSVHTKGGKRLASFGVVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKE"
ORIGIN
        1 cggatttgcc gacgcttgcg tcaaagccgg ttcgctggat ggtaaattct gccctgtagg
       61 cggtcagcct gtcatggcac aaattgctga tattctcgga ctggcagcta ctgaagctga
      121 accgatggta gcagtagtaa gatgtaacgg aagctgtgcc aaccgtccgc gtattaatca
      181 atacgacggt gcgaagagtt gcgctattgc cgcttcattg tatggtggag aaacaggttg
      241 tagctacgga tgcctcggat gtggcgactg tgtggctgcc tgccagttcg atgctatcca
      301 catgaatcct gaaacgggac ttccggaagt ggatgaagcc aaatgtacag cttgtggcgc
      361 ttgtgtaaag gcttgtccga aggcgatcat cgagattcgt ccgcaaggca agaaatcacg
      421 ccgtgtgtac atctcttgtg tgaacaaaga caagggagcc gtagcacgta aggcttgtac
      481 agtgagctgt atcggctgtg gtaagtgtgt caagacttgt ccgttcgaag ccattacgct
      541 ggagaacaac ctggcttaca tcgatccgaa caagtgtaaa tcatgccgta agtgcgtgga
      601 agtttgtccg cagaacacaa ttatcgagct gaacttccct ccacgtaaac cgaaggcgga
      661 agaagcaccg aaaacagttg ctgcagaagc tccgaaggta acagaataat aacagaataa
      721 aatacagaat tgtatgttaa agacattttc aattggtgga gttcatccac acgaaaataa
      781 attgtcggca catcaaccta tcatcacagc ggaagttcct gcaaaggcag ttattctgtt
      841 ggggcagcac attggcgcac ctgccaaacc gatagtagca aaaggtgata tggtgaaggt
      901 aggcacgaag attgccgaac ctgccggctt cgtttcggca gcaattcact cttctgtcag
      961 tggaaaagtg gcgaagattg atacagtagt cgatgcgagc ggttatgcaa aacctgctat
     1021 ctttattgat gtagaaggcg acgaatggga agaaaccatt gaccgtagca agacactggt
     1081 caaagaatgt gagctttcgt ccgaagaaat cgtgaagaag attgccgatg ccggtatcgt
     1141 aggtttgggt ggtgcttgtt tccctacaca ggtgaaactt tgtccgcctc cttcgttcaa
     1201 ggcagaatgt gtgattatca atgcggtgga atgtgaaccg tatctgactg ccgaccatca
     1261 gctgatgctg gaacacgcgg aagaagtcat ggtaggtgtc tccattctga tgaaagccgt
     1321 gaaggtaaat aaggcattta tcggaattga gaataacaag ccggatgcta ttgaactgat
     1381 gacgaaagtt gcttccagtt atgcaggcat cgaagttgtt cctttgaaag tgaaatatcc
     1441 tcagggtggt gagaaacagt tgattgatgc gattaccaaa cgccaggtgg caagtggtgc
     1501 gctgcctatc tctactgggg cagttgtgca gaatgtgggt acggcatttg ctgtttatga
     1561 agctgttcag aaaaataaac cgttgtttga gcgtgtgatt accgtaactg gtaagtctgt
     1621 ggccaaacct tccaacttcc tggctcgtat cggtacaccg atgaaacagc tgattgatgc
     1681 ttgtggcggt ctgccggagg atacgggaaa agtgatcggt ggcggtccga tgatgggtaa
     1741 ggctctggtg aatatcgaag ttcctaccgc aaaaggcagt tccggtatcc tgattatgaa
     1801 tcagaaggaa gccaaacgtg gtgaagcaca aacctgtatc cgttgcgcaa agtgtgtgag
     1861 cgcttgtccg atgggactgg agccgtactt gctcggagct ttgtccgaaa acggagattt
     1921 tgaaacaaca gaaaaatatg tatggcgtgc tgatcgcact gattccggct tttctggtgt
     1981 cgctttattt cttcggcctg ggggctctga ttgtcacggc tacttcggta gcagcctgtt
     2041 tattcttcga atgggcgatc gttaaattct taatgaagaa acctgctaca accatttgtg
     2101 acggttctgc tgtcattaca ggtgtgttgc tggcattcaa tctaccttcc aatctgccta
     2161 tctggattat cattctgggt gcactgttcg caatcggtgt aggcaagatg tctttcggtg
     2221 gtctgggctg caacccattc aacccggcat tggcgggacg tgtattcctg ttgctttctt
     2281 tcccggtgca gatgacaaca tggccggtag taggtcagct gacatcttat atggacgcta
     2341 ccaccggtgc tactccgctg gcattgatga aacaggctat tcacggcgat gcaagtgctt
     2401 tgagccagat acctgatgcg ctgactctgt ttatcggaca gaacggcgga tgtatcggtg
     2461 aagtaagtgc gctggcactg ttgctcggac tggtatacat gctctggaaa aagatcatca
     2521 cctggcatat tccggtttct atcattgtga ctgtatttgt atttgcaggc attatgcata
     2581 tggtggatcc cgaaaagtat gtttctccgg tattgcaact attctccgga ggtctgatgc
     2641 tgggagctgt ctttatggca accgactatg tgacttctcc gatgagcaag aaagggatgc
     2701 tgatttacgg tgtttgtatc ggtctgctga cggtggttat ccgtttgttc ggtgcatatc
     2761 ccgaaggtat gtcattcgcc atcctgatta tgaatgcgtt cactccgctg attaacacct
     2821 attgtaaann nnnnnnnnag aaatgaaaaa gttagaatca tctttaaaga atatgttgct
     2881 ggtacttacg ggcgttacag ctgtttccgt agcgttgctg gcttatgtga acgaactgac
     2941 gaaaggccct attgccgaag cgaatgcaaa gacgctgaac gaggccttga aaaaggttct
     3001 tcctgaatat accaataatc cggtagccga aagcgatact gttttcagcg agaaagacgg
     3061 aaagaaaatc gtggatttca ttatctatcc ggccaagaat ggcgaaaagt gggtaggttc
     3121 tgccgttgaa gccaagtcaa tgggatttgg cggtgaactg aaagtgctgg tgggctttga
     3181 tgctgaaggc aagatttata actactcttt attggcgcac gctgaaactc cgggattggg
     3241 ttcgaaagcg gacaaatggt ttggagctta tgatcctgca aagaacgaaa aaccggtatc
     3301 tcacgaagaa agtgcaaagt ctattttggg catgaatccg ggagagactc cattggctgt
     3361 gaccaaagac atgaatggac aggtagatgc tatcacggct tctactatca cttcacgtgc
     3421 tttcctgaat gcggtgaatg ctgcttatca ggcatataaa ggcggtgagg tggatacgaa
     3481 ttccggagct tcccagaaaa atgaaccggc tgctgcaccg gaaggtgaag aagctgctaa
     3541 tgacactaat aactaagaaa ggaggagaca gttatgaata attttaaagt aatgatgaac
     3601 gggattatca aagagaatcc tatttttgtg ctcctgctcg gtatgtgtcc tacactgggt
     3661 acgacatcat cggcaatcaa cggtatgggt atgggactgg ccactatgtt cgtcctgatt
     3721 tgctcgaacg tggtaatttc atctatcaag aatctgattc cggatatggt acgcatccct
     3781 tcatttatcg tggtgatcgc gtcattcgtg acactgttgc agatgataat gcaagcatac
     3841 gtgcccgatc tgtatgctac tctcgggctt ttcattccgc tgatcgtagt aaactgtatc
     3901 gtattgggac gtgcggaagc tttcgcagcg aagaacaatc cgctggcctc tatgtttgat
     3961 ggtatcggta tgggatttgg ctttaccatt gccctgactc tgttgggtgc cgtacgtgaa
     4021 ttcctcggaa caggtaagat atttaatctg accattctgc cggaagaata cggaatgttg
     4081 atctttgttc tggctccggg tgcctttatc gctttaggtt atctgattgc cattattaat
     4141 agtctgaaga aagcctaact ctattaaata agaaaagaat atggaatata tattgatatt
     4201 tatctcggca atctttgtaa acaacatcgt gttgtcgcag ttcctgggta tctgtccgtt
     4261 cctgggtgtt tccaagaagg tggaaacagc gatgggtatg agtgcggcag ttgctttcgt
     4321 gctgactatc gctaccatcg tcacattcct gattcagaag tttgtgttgg atgctttcgg
     4381 attggggtac ttacagacaa tcacttttat tctggttatt gccggactgg tgcagatggt
     4441 agaaattatt ctgaagaaag tttctccttc tttgtatcag gcactggggg tgttcctgcc
     4501 gttgattaca acgaactgct gtattctcgg tgtggcaatc ctggtaatcc agaaagactt
     4561 tgatctgctg acaggtgttg tatacgcatt ctctactgct cttggctttg gtctggcact
     4621 ggtattgttt gccggattgc gtgagcagat gaccctggtg aagattccga aaggaatgca
     4681 ggggactccg attgctttga ttaccgcagg tttgctggca atggcattca tgggcttctc
     4741 tggcgtcgtg taaaagacta agttgataat tagataaaga ggctggaaac tctgtcgtat
     4801 ggcaacatac aggcagtttg tttccggcct ttttctttat atctgttcat accgaatatg
     4861 ttttttatca taccaaaacg ccctcaaatc gtcccgtaag tatcttcctg tgaataaaat
     4921 tgcgatagtt tattgcattt ccattttatt tccatacatt tgtacctcaa acaaactgaa
     4981 aaccgaaaaa ctaaccatat tttaaaatta tatgaaagaa agaattttag taacgggagg
     5041 aacaggctat attgggtctc ataccgttgt agaactacaa aacagtggat acgaagtaat
     5101 cattatcgat aatttatcaa attcgagtgc tgacgttgtt gacaatatag agaaagtatc
     5161 cggtatccgc ccagcttttg agaaactgga ttgtcttgat tttgctggcc ttgatgccgt
     5221 atttgccaaa tataaaggaa ttaaagcgat tattcatttc gcagcaagca aagcagtagg
     5281 agagtcggta gagaagccgt tgctttatta tcgtaacaac ctggtttctt taatcaacct
     5341 tctggagtta atgcctaaac atggagtaga aggcatagtg ttctcttctt cctgtacagt
     5401 atatggtcaa ccggatgagt tgcctgtaac ggaaaaggct ccgatcaaga aagcggaatc
     5461 tccttatgga aatacaaaac agattaatga agaaattatc cgtgatacaa tagcttccgg
     5521 tgccccgatc aatgctattt tgctgcgtta tttcaatccg attggcgcac atcctacagc
     5581 attgctgggt gaacttccga acggtgttcc tcaaaacctg attccttatc tgactcagac
     5641 agcgatgggt atccgtgaaa aactaagtgt attcggtgac gattatgata ctcctgacgg
     5701 ttcttgtatc cgtgacttta tcaacgttgt tgacttggct aaagcacacg tgattgcaat
     5761 ccgccgtatt ttggagcaaa aacagaaaga aaaagtagaa gtattcaata tcggtacagg
     5821 acgcggcgtt tcagtattgg aactgattaa tggctttgaa aaagctaccg gcgttaaatt
     5881 gaattatcag attgtaggcc gtcgcgcagg tgatattgaa aaggtatggg ctaatcccga
     5941 ttatgcaaac caggaactgg gttggaaagc ggtagaaaca ttagaagata ctttacgctc
     6001 tgcatggaat tggcagctga aactccgtga aagaggcatt cagtaaaaag atatttgttt
     6061 taattaacat aaaagtttaa acaaatcgtt catgcgattt gtttattaga tgctaatcag
     6121 cttgatctgt ttgtgagtat gtgaatatga gtaaatggta cttatgcctc tccggcatag
     6181 acaggtatga ttgcatagta gttttgtcgt gttttatttt gtgtttgtgt tgtgacggta
     6241 ctacgacggg agtcgtggta ccgttttttg ttactctttt acagcctgcc tttaaaacag
     6301 aatacgttag ttccccaatc ggtttcaggt aaagtccctt ccggttcgaa caatccatat
     6361 acggaagaac cggaaccgct catagaggca taaacagccc cttgcctgta tagctcggct
     6421 ttaatttctc cgatcaccgg atgctggggg aatacgctgt cttcaaaatc attgattaat
     6481 atctctttcc attcatttac cgggcgttta atcgcttctt tgatcgagta ttcgggatga
     6541 tgagggtgaa tattggcgaa agcttcccgc gttgatacga atacatccgg tttgatgatc
     6601 agaatcttat atccttttaa ggatagtgga atgggggaga atatgttgcc gattccttcg
     6661 gcaaaggtcg gggcgttttt gataaagaaa gcgcagtctg ctcccaaagt tgcggcatat
     6721 atttccagct gatcttcgga taaattcagc tgaaagtgtt cgttgagtaa tttcagcatg
     6781 aaagccgcgt ctgatgagcc tcctcccagt ccggcaccgg aaggaatgtg tttgtacaga
     6841 tggatctcga taggacagag gtgaaactct ttatctaata gcagatatgc tttcaccact
     6901 aaattgtctt ctggattacc ggatatctcc attccgtact gatgcaggga gaactttttg
     6961 tccgcttcgg ggctggtccg gatttccagc gcatcttcga gagcgacggg gtagaatacg
     7021 gtttcgaggt tgtgatatcc gtccggacgc ttctcggtaa tagagagtcc caggtttatt
     7081 tttgcgtttg ggaaagtgat catattcgtt ctgaattatt atttttgaat tttaaattat
     7141 gggttgcgaa tttatgctat tggtgacaaa gttactaaaa tcttcatttt tccttatctt
     7201 ttcttcatta ttatattcta tctttgtcat ccctttcggc ttttactatg tataaaagcc
     7261 ggggatcata aattgtaaat cataaaattg tatataagca gatggctgaa caaagaagaa
     7321 attcccgtaa cacaaaatca actaaagtac aaccggtcaa tgattatggt cgtatccaac
     7381 ctcaggcacc ggagctggaa gaggcggtgt tgggtgcttt aatgattgag aaggatgctt
     7441 attcgctggt gagtgagatt cttcgcccgg agtcatttta tgagcatcgt catcagttga
     7501 tttatgctgc cattactgat cttgccgtta atcagaagcc ggtggacatt ctgacggtca
     7561 aagagcagtt gagcaaaaga ggtgagttgg aagaggtcgg tggaccgttc tatattactc
     7621 agttgagcag taaggttgct tcttccgcac atatcgaata tcacgcccgt attattgcac
     7681 aaaaatcgtt ggcgcgcgaa ttgataacgt ttaccagtaa tattcaaagc aaggcttttg
     7741 atgagacact ggatgtggac gacttgatgc aggaggcgga aggcaagctg tttgagattt
     7801 cccagcagaa tatgaagaaa gactatacgc agattaatcc ggtaattgac gaagcgtata
     7861 agctgattca gaaagcggct gcacgaacgg acggtctgag tggtcttgaa agtggattta
     7921 cgaaactgga caagatgacc tccggttggc agaactccga ccttattata atcgctgccc
     7981 gtcctgccat gggtaagaca gctttcgtac tttctatggc taagaatatt gctgttgatt
     8041 atcggaatcc ggtagcgttg ttctctcttg aaatgagtaa cgtccagttg gtcaaccgtc
     8101 ttatcaccaa tgtttgtgag attccgagtg agaagatcaa aagtggacaa ttggcaagct
     8161 atgagtggca acagttggac tacaaactga aagatctgct ggatgctccg ctttatgtgg
     8221 atgatactcc gtctttgtct gtgtttgaac tccggaccaa agcacgtcgt ctggtgcgtg
     8281 aacatggggt gagaattatt attattgact accttcagtt gatgaatgcg agtggtatgg
     8341 cattcggtag ccgtcaggaa gaggttagta cgatatcccg ttcgttgaaa ggattggcga
     8401 aggagttgaa cattcccatt atagccttgt cgcagttgaa tcgtggtgtg gagagtcgtg
     8461 aaggtattga cggtaaacgc cctcagttga gtgaccttcg tgaatccgga gccatcgagc
     8521 aggatgccga tatggtgtgt tttattcacc gtccggaata ttataagatt tatcaggatg
     8581 atcgtggtaa cgaccttcgc ggtatggcgg aaattgtgat agccaagcat cgtaatggtg
     8641 cggtaggtga agtcttgctc cgattcaaag gtgagtttac acgattctca aatccggaag
     8701 atgatatggt tataccgatg ccgggtgaac ctgcaggtgc catgctgggg tctaaactga
     8761 atgccggtgc tatgcctccg cctccgccgg aaccggactt tgttccgcag ggaaataatc
     8821 cgttcggtgc aacggaagga ccgttacctt tctaaaaaac gttcgtttgg gttgaataga
     8881 aatgaccgct tagtcagatg aaaataaccg ctcgatttac tccaatcgag cggtcgatta
     8941 ttttttatag agtatagccg ggttgtattc tgatggggat aggtggcaaa aatgacaaag
     9001 aatacccctt tattttttgc cactttgtca ccaaccatga atttattggg gaataataca
     9061 gtcaggtcct tgttagttta gcttctcttg acatttttct ctcaaatcgt tctatgtcaa
     9121 ccgaaaaatc ttattaactt tgcgaaactt tttgagaaac aataaaaatt taattatatg
     9181 aatatctctt ataactggct gaaagagtat gtcaactttg atttgacccc cgatgaaacg
     9241 gctgctgcgc tgacctcaat cggcttggaa acaggtggtg tagaagaagt gcaaaccatt
     9301 aagggtggtt tggaaggact cgtaatcggt gaagtgctga cttgcgaaga acatccgaat
     9361 tccgaccatt tgcatatcac taccgtcaat ctgggagacg gcgaacctgt acagattgta
     9421 tgcggtgctc cgaatgtagc tgccggacag aaagtagtgg ttgccacttt gggtaccaaa
     9481 ctttatgacg gtgatgaatg ctttactatc aagaagtcaa aaatccgtgg tgtagaatct
     9541 acagggatga tttgtgcaga agacgaaatc ggtattggta ctgatcatgc aggaatcatc
     9601 gtgttgccgg ctgaagctgt tccgggtact ctcgccaaag actattataa tatcaagagt
     9661 gactacgtac tcgaagtaga tattactcct aaccgtgcag acgcttgctc acactatggt
     9721 gtggcccgcg acttgtatgc ttacctgatt cagaatggca agcaggctac tttgcaacgt
     9781 ccatctgtag atggatttaa ggtggaaaat catgatttgg atatcgaagt agtggttgaa
     9841 aacagcgaag cctgtcctca ctatgccggc gttacggtga aaggcgttac tgtgaaggaa
     9901 agccccgaat ggttgcagaa taaattgcgc ttgatcggtg tacgtcctat taataatgta
     9961 gtggatatta ctaattatat cgttcatgct ttcggtcagc cattgcattg tttcgatgcc
    10021 ggaaagataa aaggcaatga agtaattgtc aagacattgc cggaaggcac tccattcgtc
    10081 acattggatg aagtggaacg caagttgaac gaacgcgatc tgatgatctg caacaaagaa
    10141 gaagcgatgt gtattgccgg tgtattcggc ggactggatt ccggttctac ggaagctacg
    10201 acagatgtat ttatcgaaag cgcttatttc catcctacat gggtgcgtaa gactgcccgt
    10261 cgtcacggtc tgaatacgga tgcttctttc cgtttcgaac gtggcatcga tccgaacgga
    10321 gtaatctatt gtctgaaact ggctgctctg atggtgaaag aactggccgg tggcactatc
    10381 tcatccgaaa ttaaggatgt ttgcgttgca gctccacaag actttatggt agaactttct
    10441 tatgagaaag taaattcgct gattggtaaa gtgattcccg tggaaacgat caagagcatt
    10501 gttaccagcc tggaaatgaa aatcatgaat gagacagttg acggactgac attagccgtt
    10561 cctccttatc gtgtagacgt acagcgtgat tgcgatgtga tcgaagatat tctacgtatc
    10621 tacggatata ataatgtaga aatcccgact acgctgaact ccagtctgac aaccaagggt
    10681 gagcatgata aatcaaacaa attacagaat ctggttgcag aacagttggt tggctgtggc
    10741 ttcaatgaaa tactgaataa ttctctgact cgtgccgctt actacgacgg tctggagaac
    10801 tatccatcca accatctggt gatgctgctg aatccactga gtgccgatct gaactgtatg
    10861 cgtcagacat tgctgttcgg tggactggaa agcatcgctc acaatgcaaa ccgcaagaat
    10921 gccgatttga aattcttcga attcggtaat tgctattact tcgatgcgga caagaagaat
    10981 ccggaaaaag tactggctac ctattcggaa gactatcact tgggtttgtg ggtgactgga
    11041 aagaaagtcg ctaattcatg ggcacacccg gatgaaaaca gttcggtata cgaactgaag
    11101 gcttatgtag aaaatatatt gaaacgtttg ggactggatt tgcacaacct ggtagttggc
    11161 aatctgactg acgatatttt cgctaccgca ctttctgttc ataccaaggg ggggaagcgt
    11221 cttgcctctt tcggtgttgt gacgaagaaa ctgctgaaag cattcgatat agataatgag
    11281 gtgtattatg ccgacttgaa ctggaaagaa ctgatgaagg ctatccgttc tgtgaagatc
    11341 agctacaagg aaat
//
