LOCUS       gnlProkkaGLHEDEIN_38   10315 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLHEDEIN_38.
ACCESSION   gnlProkkaGLHEDEIN_38
VERSION     gnlProkkaGLHEDEIN_38
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:03:29
            Original ID  :: gnl|Prokka|GLHEDEIN_38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10315
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10315
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2453:6718]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2454..6718
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10315
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10315
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             147..671
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             675..1160
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             1157..2440
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             2454..3152
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             3172..4473
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.4e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.1e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             4485..5621
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             5618..6718
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg38_7_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_7"
                     /sec_met_domain="Aminotran_5 (E-value: 8.5e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVLKY"
     aSDomain        5708..6496
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_7_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg38_7_Aminotran_5.1"
                     /locus_tag="ctg38_7"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             6738..8231
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_8"
                     /sec_met_domain="Polysacc_synt (E-value: 4.5e-11, bitscore:
                     32.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKKNVVKWNFVFYLLEFLYTILVGIILVPLYLKYIPKDLYGFW
                     LATGNILSILTLINPGFSDVIQQKVAYCYGLHDYKKIGLYTVSGICLTFVFSLIVLIIG
                     VVVNLLIGSIFTMQANYLYELKIAFGLMLVGTFLTINYYSFSSILYAFLSSKSIGLIVL
                     LGNSLGTLISIYLIIHGYGLIALGIASVVRGGVFLSCSVGYVIFKFRKKKIKIVFDLNN
                     VKEIFSFSIYNFLGKTGQTLLTNMNSFLTAKFVSPIDAANLRFTQTVPEFGKVLVLRFL
                     YSVAPIIPNLLAAKGLESIRIKLLNIVYFLISFIFLVCIGFYLLNEQFIYLWLGENNFS
                     GKIINFFIIILLFFSSINKVCFQFLFALGDIKKSNKILFYQSLLYLPIAVFTTKFCGII
                     GLLLSGILVELLALFIFFFPKMVDILNISKIDIRKKLFVELTKISFVTVITLLIGSCVK
                     FSNPSWLLFFVEIVFIVLTFFVLLFLCSKTFRNLLSICK"
     CDS             8235..9380
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MKILLVFIDMIRVDHLSLYNDNMEKTSLDLFFENLGGTILTNCYT
                     PAPDTPRSIACLQSGLLPYLNGCDSRVKWPRYFMKPNIETIFDIAVGLGYKVNLCATKS
                     DIETGLFKFKENENISIFTTIEDFTDTVHLSENTLSLIAIDDYHSAIDDYGGTSLGIKE
                     GQKVILYSLNNFLTPDIVNKYDYSFFFSDHGHALQSEIVMQKNKLELLSDGRTKLFMFY
                     HNINNKKIVKDSRLASILDLYASIVDLIGSGDFRQGFSFFRDSQRDILHIEDHADFRVS
                     PEQIVSQWRVISDEIDIRTNVFETLNKKGQIIDINVVKKYLDSFSPSFSYYMKQIEILK
                     MYEKMKQRKTHYFNGVKRANWWIRCYVRIINRLYILINRLK"
     CDS             9377..10246
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MIVSSLRGGLGNQMFIYAMVKAMALRNNVPFAFNLTTDFANDEVY
                     KRKLLLSYFALDLPENKKLTFDFSYGNYYRRLSRNLGCHILHPSYRYICEERPPHFESR
                     LISSKITNAFLEGYWQSEKYFLDYKQEIKEDFVIQKKLEYTSYLELEEIKLLDKNAIMI
                     GVRRYQESDVAPGGVLEDDYYKCAMDIMASKVTSPVFFCFSQDLEWVEKHLAGKYPVRL
                     ISKKEDDSGTIDDMFLMMHFRNYIISNSSFYWWGAWLSKYDDKLVIAPGNFINKDSVPE
                     SWFKLNVR"
     CDS             10254..10313
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MNVLVTGAAGFIGSHVCKRL"
ORIGIN
        1 acgaacgttt tttgaaacac attcgttcgt tctcaacttc taaaaatgtt tcgtaaaatt
       61 tgacggtttg aaagagaaaa gatgtctcgt tcaaaccgcg aagcgcaccc gaaacaaagg
      121 aaaatttccc caagtataaa tcgtaaatgt ctgaacaaca gaagtattgg tttgccgccc
      181 gtacccgaga taaacaagag tttgctattc gtgactctct tgaaaaattg aagactgaac
      241 ttgatctcaa ttactatctt cccactcagt ttgtcatccg gcagttgaaa tatcgtcgaa
      301 aacgggtgga agtccctgtt attaagaatc ttatcttcat ccaagctacc aagcaagatg
      361 cttgtgatat ttctaataaa tacaatatcc agctttttta tatgaaagac ctgcttacca
      421 gggctatgct gatagttcct gataaacaga tgcaggactt catatttgtc atggatttag
      481 atccgaatgg cgtcagtttc gataatgacc atttatctgt cggtagcagg gttcaggtag
      541 ttaaaggtga tttctgtggt gtcgagggcg aacttgccag cgaggccaac aaaacttatg
      601 ttgttattcg tattgccggt gtattgagcg ccagcgtcaa agttcctaaa agttatttac
      661 gtgtcattta agttatgaat acactcactt ctcaaattga acaattacag agtctcgcgc
      721 acgagttact ctatttaggt gtggatggtg ctcctattta taccgatcat ttccgtcagt
      781 tgaacaaaga agttttagaa caatccgatg cgttgtatcc tcagcgtggt gctactcccg
      841 aagaggaagc aaacatctgt ctggcattat tgatgggtta caatgcaacc atctataatc
      901 agggtgacaa ggaggagaaa aagcaagttg ttctcaatcg ttgttgggac gtgcttgacc
      961 aacttcctgc tactttattg aaatgccagt tattgactta ttgttatggt gaggtgtttg
     1021 aagaggagtt ggcgaaagag gcgcatacta tcatagaaag ttggagcaat cgagaacttt
     1081 taaaagctga aaaagaaata gctgaaagtt tgaataattt ggaagctaat ccatatccgt
     1141 acagcgaact acacgaatga ttcgttcctt tctttcccgt tctccccttt acgttttggc
     1201 tctctatgcc agcgttttga tttttctggt ttatacttgt gcctatgcct accgtaagcc
     1261 atttaccgca gccatttatg aaggtgagat tctttgggga ttcgatgtca aaattctgta
     1321 tgtcctttct gagattatcg gctacgccct ttccaagttc atcggtgttc gtattttgcc
     1381 ttcgatgaaa gcgggtcacc gcatctatta tataataggg ctgcttactt tttccgaagt
     1441 tgctttgttg ggttttgcac ttcttccggt tcctttgaag gtgtgttcta tttttctgag
     1501 cggtcttccc ctgggtatga tctggggtgt catttttagc tatatcgaag ggcgtcgtat
     1561 cagtgaaata ttgaatgtcg ggctgagcgt tgctttgata gtctcttccg gtttggtgaa
     1621 aaccttggga caattcgtga tggataattt gcatgtgtcg gaatattgga tgccttttac
     1681 cacaggtttg ttggtatacc ctgttatgtt gctttgcagc tggcttctca atcagattcc
     1741 ggctcccaat gagcaagata tcatacagcg taccaaacgt gctccgatgg atggtaaaga
     1801 caggcgtaaa tttttgaggc aattcttctg gggaatctgc atgctggttg ttttttacgg
     1861 tgccctgacc gtgttccgtg agcttcgtga ctctttcgct gccgatattt ggaaggagct
     1921 ccatattgag ggtgcaatga tctttactca gacagaggtt cccattgccg tttttgtcct
     1981 tgtactgatg ttcctgattg tgtttgtccg taataaccgt ttggctctta atatcattta
     2041 ttgcattgcc gtcacaggcg gttccttaat ggttttttcc acattgcttt atgtgtacgg
     2101 ttttctttct cctatttggt ggatgattct ttccggtctt ggtctgtata tggggtatat
     2161 tcctttcact tacctgatag aacgtctgat tgcttccctt agggtggtta gtacggctgt
     2221 ttttattatt tatttggccg attctttcgg ctatctgggc actacgggtg tgtttatggt
     2281 caagaacttc gtttctgctg acatttcctg gactgtcatg ctaatgcgta ctgccctttt
     2341 ttcaggattt gtttctgtcc tgtcgatttt tgcgatttac tgttatttca agcaacaatt
     2401 gaattcactt atattaattc cctctgaaat tcatgattaa aacagcaatg atcatggctg
     2461 ccggtcttgg tacccgcttc gggcattata ccgagcttgt gcccaaaggt tttgtggagg
     2521 ttggtggaaa acctatgatt atccgctcta tcgaaaccct tctttcctgc ggtatcgaac
     2581 gtatcatcct cggtacgggt tataaaaaag aggcttatga agcccttcag gcggatttcc
     2641 cccagataga gacctgtttc agtccccgtt atgccgatac taacagtatg tacactctgt
     2701 acaatacgcg tgacgtgata ggcgatgaca gtttcctgct gcttgaatcg gaccttgttt
     2761 ttgaacgcaa ggccatcctt tcgctgctgg atgacgaatt cccggatgtg atgcttgtct
     2821 cttctctgac caagttccag gatcagtatt atgtggaata tgaccgcaat cacatcctta
     2881 cttcctgttc ggtagacaag aacgcccttg aggcaaaagg cgagctggtc ggtatccata
     2941 aactttccaa tactttctac cgccggatgt gcgccgatta tgcgaccatc ctggagtccc
     3001 agcctaaact gggttacgaa tacgaactgc tccgcatgtc ccgttccgtt tcccctgtcc
     3061 gtgtgctcag ggtggagggt cttaaatggt atgaaatcga tgatgaagcc gacctttcgt
     3121 atgccgagga gcacatcatc cgctattgtt aaaaacaaat cttttccata tatgaacaag
     3181 aaaatttatg tcggtatgac cgcggatatc atgcatccgg ggctgatcca tattattcat
     3241 gaagctacta aatacggtga tgtcatcgtc ggtctgctga cggacaaggc catcgccgaa
     3301 cacaaacgcc tcccttacct tacctatgat cagcgtaagg aggttgttga gaatatcaag
     3361 ggggtttttg aggttgttcc ccaggaggac tggagctatg ttccgaatct ggaaaaactc
     3421 aagcctgact atatcatcca cggcgacgac tggaaaacgg gcccgttgcg cgaggtgcgc
     3481 gaacaggttt ttgaggtgat gaacgcccag gggggcaagg taatcgagat cccttatacc
     3541 cggggcatca actcctcctc gctcgacaag gatatcaagg cgatcgggac tacccctgac
     3601 gtacgtctta agtccctccg ccgcctgatc caggccaagc ctgtggtccg tatcctggag
     3661 gctcacgacg gtctttgcgg tctgattatt gagaatcttg aagtccagaa gggggataag
     3721 cgcgaggtct ttgacggcat gtggtccagc agcctgaccg actccacgag taagggtaaa
     3781 ccggatattg aagcggtcga ccttaccacc cgtttacagg acctgaacaa tatccttgaa
     3841 tgtaccacca agcctattat ttttgatgga gacacgggtg gcaagatcga acactttgtc
     3901 tttactgtgc gcactctgga acgtcatggc atttctgcag taatcattga agataaagtc
     3961 ggtctgaaga agaattccct ttttggtact gacgctatcc agactcagga tagtatcgag
     4021 ggtttctgcg ataagatcag agcagggaag aatgcccagg tcaccggtga ctttatgatc
     4081 attgcgcgta tcgaaagcct tattgccggc aaacccatga gtgacgccct cgaacgtgct
     4141 tatgcctatg tacaggcggg tgcggacggc atcatgatcc acagcaagga taagtcgggt
     4201 gaggatatcc gtgagttctg ccggactttc cgcaaagaat acgcccatgt tcccattgtc
     4261 gttgttccga cgacttatga ccatgtgcac gaatccgaac ttcacgaatg gggtgccaac
     4321 gtagtcattt acgccaacca ccttctccgt gccgcttacc cggccatgat gaacgtggcc
     4381 aggaccatcc ttgaaaacga gcgcgccgag gaggtccgtc cgctttgtat gcctatcaag
     4441 gaaattctgg aattgattcc gggcactaaa taaatcagac ggttatggta agtgtagaaa
     4501 agatatacga tacgttcctt catcacggtg ttgacttctt tacgggtgtt cccgattccc
     4561 ttttgaagaa tatttgcgcc tatatcacgg atcatgctcc gcgtggtaag catatcatcg
     4621 ccgccaatga aggttccgcg gtgggcattg cctgcggtta ttatatggct tctggcaacg
     4681 ttcctttggt ttatatgcag aactccggtc tgggaaatac ggtgaatccc ctcttgtccc
     4741 ttgcggacga gaaagtgtac agccttcctc ttcttttgct ggtcggctgg cgcggtgagc
     4801 ccggcacaaa agacgaaccc cagcataaga agcagggcga ggttaccctt gatcttctga
     4861 aagccatgaa aattcctttt ataattctgg atacggatga agacgaggcc ctggcgcaga
     4921 tccatgacgc ggttgtctcg gcgaagagcc ggtcgattcc ccatgcgatt gtcatccgta
     4981 aagatacgtt tggaaaatat aaattgcgtc aggaagcctt gaatgactat cctctgtccc
     5041 gcgaggaggc gctaatgcag gttgtcgacc acctcgggga caatgacatt gtggtttcca
     5101 ccacgggcaa gctctcccgt gagcttttcg agtaccgtga atcgaaaggg caggggcacg
     5161 caagggattt cctaactgtg ggttccatgg gtcacagttc ttccattgcc ctggggattg
     5221 cccttgagaa gcctgaccgc cgtgtctact gtcttgacgg tgacggtgcc tttatcatgc
     5281 acatgggtgc tgtcagcaat atcggcgatc tttctcccaa gaattacagg cacgtccttt
     5341 tcaacaacgg tgcgcatgaa tctgtcggcg gtcaacccac gctcggtttc cgtctggata
     5401 tcgcctcgat agcgaaaggt tgcggttatg cgcatgtact gactgcctcc gacaaggaag
     5461 ggctttcgtg tgcgcttgag aagctgtccg gcctgtccgg cccggttctt cttgaaatta
     5521 aggtccggat cgattcacgt gatgatctgg gtcgccctac gactactccg gtagagaata
     5581 aagagcattt tatggcattt ttaaaagata cgcattcatg aatatcgaaa gaaagatcct
     5641 tttgaatccg ggtcccgcca ccacgacgga tacggtaaag ctggcgcagg ttgttcccga
     5701 tatctgtccg cgtgagaaag agtttgcggg tatgatgaaa cagttacgtg acgacctggt
     5761 ccgcgttgcg catggagacc tctccaaaca tacggccgtc ctgttttgcg gctcgggtac
     5821 gatcaatatc gatatctgcc tgaactctct tcttcctgcg gataagaaag ttctggttgt
     5881 caataacggt gcctatagca cccgtgcggt ggaagtctgc gaatattacg gtcttcccca
     5941 tatcgatttg aagttttccg tttacgaact tcccgacctg tcggtaatcg aaaagacgct
     6001 ttccgacaat ccggacatcg ctttggtcta taccacgcac catgaaacgg gtacgggtat
     6061 cttgaacccc atccgtgaga tcggaaaaat agcccattcg cacggtgccg tttttgttgt
     6121 cgacaccact tcctccctgg gtatgattcc ttttgatatc gggaaggata atgttgactt
     6181 ttgtatggct tcggctcaga aaggccttca ggccatgacg ggtctttcct ttatcatagg
     6241 tgatgaatcc ctgatacgtg cttcaaggga ttatccgaaa cgctcctact attgtaacct
     6301 ctatttacaa tacgattact ttgagaagac gggtgagatg cattttactc ctcctgttca
     6361 aaccgtttac gctgcccgtc aggctcttga tgaatatttt gcagtaggtg aagaggctaa
     6421 attcgcccgt cacaagaggg tctttgaagc catccataaa ggtttgcaag agcttggtct
     6481 tcagtatgcg atcaaacgtg aatggcagtc gggtcttgtt gtttctgtat tgtatcctga
     6541 tgatcccctc tgggattttg ataaggttca tgattactgc tatgaacgtg gctttacgat
     6601 ctacccgggt aagatttcca caacgaatac attccggctt tgtgcgttgg gagagattga
     6661 tgtggaggat attgagaggt tctttgaggt gatgagggag gctgttttaa aatactagag
     6721 aaattgtcaa ttgggatatg aaagataaaa aaaatgtagt aaaatggaat tttgtatttt
     6781 atctcttgga atttttgtat acaattttag ttgggattat tttggttccg ttgtatttga
     6841 aatatattcc aaaggattta tatggtttct ggctagctac tggtaatata ttgtctattt
     6901 taactcttat caatcctggg ttttcagatg tgatacaaca aaaagttgca tattgttatg
     6961 gattacatga ttataaaaaa ataggattat ataccgtttc aggtatttgt cttacgtttg
     7021 ttttttcatt aattgttttg ataatcggag tagtagttaa ccttttaata ggtagtatat
     7081 ttacaatgca agctaattat ttatatgaat taaaaatagc ttttggctta atgcttgttg
     7141 gtacattttt aactattaat tattattcct tttcttctat attatatgct tttcttagta
     7201 gtaagtcaat cgggctaatt gtacttctag gcaatagttt aggtacttta atatctattt
     7261 atcttattat ccatggatat ggtctaatag ctttgggaat tgcatcagtt gttcgaggag
     7321 gtgttttttt gtcatgtagt gttggctatg taatatttaa atttcgaaaa aagaaaataa
     7381 aaattgtatt tgatttaaat aatgttaagg agatcttttc tttttctata tataattttt
     7441 taggtaaaac aggacaaaca ttgttgacta atatgaattc tttcttgact gctaagtttg
     7501 tttctcctat tgacgctgca aatttgagat ttactcaaac tgtgccggaa tttggtaaag
     7561 ttttagtttt aagattttta tattctgttg ctcctattat tcctaatttg ttagcagcta
     7621 aggggttgga gtctattaga ataaagcttt tgaatattgt gtattttttg atttccttta
     7681 ttttcttagt atgtattggt ttttatctat tgaatgaaca atttatatat ttatggcttg
     7741 gtgagaacaa tttttcaggg aaaataatta atttttttat cattatttta ttgttttttt
     7801 cttctataaa caaggtctgt tttcagtttc tttttgcatt aggagatata aagaaaagca
     7861 ataagatttt attttaccaa tctttgttgt atttacctat tgctgttttt acaacgaaat
     7921 tttgtggaat aattggttta ttgttatctg gaatattagt agaattattg gcactattca
     7981 ttttcttctt tcctaaaatg gttgatattc ttaatatttc gaaaatagat attagaaaga
     8041 aactttttgt ggagttaacc aaaatatctt ttgttacggt tattacatta ttaataggtt
     8101 cttgtgtcaa gttctctaat cctagttggc tacttttctt tgtggaaatt gtttttattg
     8161 tattaacatt ttttgttttg ttgtttttat gttcaaagac ttttcgtaat ttattgtcta
     8221 tttgtaaata aaagatgaag atactactag tttttataga tatgatacgt gttgatcatt
     8281 tatcattata taatgataac atggagaaaa catcgttgga tttgtttttt gaaaatttag
     8341 gaggtacaat tctaactaac tgttatacac ctgcacctga tactccaaga agtatagctt
     8401 gtttgcaaag tggcctatta ccctatttga atggctgcga tagtcgtgtc aaatggccaa
     8461 gatattttat gaaacctaat atagaaacta tttttgatat tgcagtaggg ttaggatata
     8521 aagtaaattt gtgtgcgact aaatctgata ttgaaacagg gttgtttaag tttaaagaaa
     8581 atgaaaatat tagtatattt actactattg aagattttac tgatactgtt catttgtcag
     8641 aaaatacatt gtccttaatt gccattgatg attatcattc tgccattgat gattatggag
     8701 gaacctcatt gggaattaaa gaagggcaga aagtgatatt atattcttta aataattttc
     8761 taactccaga tatcgtaaat aaatacgact attcgttttt cttttcagac catgggcatg
     8821 ctttgcagag tgaaattgtc atgcaaaaaa ataaactaga actacttagt gatggaagaa
     8881 ctaaactttt tatgttctat cataatatta ataataagaa aatagtaaaa gattctaggc
     8941 ttgcttctat tttggatctt tatgcctcta ttgttgattt gattggtagt ggagatttta
     9001 ggcaaggttt ttcctttttt agagacagtc aaagagatat acttcatata gaggaccatg
     9061 ctgattttag ggtgtctcca gagcaaattg tgagtcaatg gcgagtaatt tcagatgaaa
     9121 tagatattag gactaatgta tttgaaactt taaataaaaa aggacaaata atcgatataa
     9181 atgtggtaaa aaaatattta gatagttttt ccccctcgtt ttcttattat atgaaacaga
     9241 tagagattct aaaaatgtat gagaaaatga aacaacggaa aacgcattat tttaatgggg
     9301 taaagcgagc taattggtgg atccgctgtt atgttagaat tataaatagg ttatatatac
     9361 taataaatag attgaaatga ttgtatcatc tttgcgagga ggattgggga atcaaatgtt
     9421 tatttacgct atggtgaagg ccatggcatt aagaaacaat gtaccattcg cttttaattt
     9481 gactactgat tttgcaaatg atgaagttta taaaaggaaa cttttattat catattttgc
     9541 attagacttg cctgaaaata aaaaattaac atttgatttt tcatatggga attattatag
     9601 aaggctaagt cgtaatttag gttgtcatat acttcatcca tcatatcgtt atatttgcga
     9661 agagcgccct ccccactttg aatcaaggtt aattagttct aagattacaa atgcttttct
     9721 ggaaggatat tggcagtcag aaaaatattt tcttgattat aaacaagaga taaaagagga
     9781 ctttgtaata caaaaaaaat tagaatacac atcgtatttg gaattggaag aaataaaatt
     9841 gctagataag aatgccataa tgattggggt tagacggtat caggaaagtg atgtagctcc
     9901 tggtggagtg ttagaagatg attactataa atgtgctatg gatattatgg catcaaaagt
     9961 tacttctcct gttttctttt gtttttcaca agatttagaa tgggttgaaa aacatctagc
    10021 gggaaaatat cctgttcgtt tgataagtaa aaaggaggat gatagtggta ctatagatga
    10081 tatgtttcta atgatgcatt ttcgtaatta tataatatcg aatagctctt tttactggtg
    10141 gggagcatgg ctttcgaaat atgatgataa gctggtgatt gctccaggta attttataaa
    10201 taaggattct gtaccagaat cttggtttaa attgaatgta agataaaatc ttaatgaatg
    10261 tattagtaac cggtgctgcc ggatttatag gttcgcatgt ttgtaagcgt ctttt
//
