LOCUS       gnlProkkaLKKJNABI_315  10688 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LKKJNABI_315.
ACCESSION   gnlProkkaLKKJNABI_315
VERSION     gnlProkkaLKKJNABI_315
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:54:04
            Original ID  :: gnl|Prokka|LKKJNABI_315
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10688
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10688
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7459:7807]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7460..7807
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10688
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10688
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..218)
                     /locus_tag="ctg315_1"
                     /transl_table=11
                     /translation="MLAERGQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKK
                     RLHVYHSQTSPLIDWYKNEKKYQHING"
     CDS             complement(269..367)
                     /locus_tag="ctg315_2"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVXXXXSKIAKV"
     CDS             complement(401..937)
                     /locus_tag="ctg315_3"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(979..2523)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg315_4"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(2716..2940)
                     /locus_tag="ctg315_5"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             3213..4046
                     /locus_tag="ctg315_6"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDRTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             4512..6023
                     /locus_tag="ctg315_7"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             6097..7161
                     /locus_tag="ctg315_8"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             7183..7470
                     /locus_tag="ctg315_9"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(7460..7807)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg315_10"
                     /sec_met_domain="PF05402 (E-value: 1.3e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 4.7e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(7852..9240)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg315_11"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(9531..9926)
                     /locus_tag="ctg315_12"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEASATETPAPAAE"
     CDS             complement(9949..10686)
                     /locus_tag="ctg315_13"
                     /transl_table=11
                     /translation="MIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNLYILHDINF
                     GAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTLALIDAFLS
                     TAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEKSETDPVVY
                     LKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVKQQRYSKAL
                     EIIKKLSLKYPKKNAXXXXEIDY"
ORIGIN
        1 agaccgttga tatgctggta tttcttttcg ttcttgtacc agtcaatcag cggagatgtc
       61 tgtgaatgat atacatgcag acgttttttg attgtttctt cgttgtcgtc ggcacgaccg
      121 gagtctttgc cacgtttgat cagacgtacc atcagttcat cttccggaac ttcgagatcc
      181 aacattacag aaacatcctg tcctctttcc gccaacatct tctttaatgc ttccgcctgt
      241 gcaattgttc ttgggaaacc gtcgaaaatt acacctttgc tatctttgaa gnnnnnnnnn
      301 ntacaatacg ttcgctctgt gttccttttc ctgaacccgg agcaccgaaa attacaatgt
      361 tcaacatctt ttttacctaa aaattaattt gtatttgaat ttaatctact acagtataaa
      421 tatcgggata attgcgtccg aaaccatcat aatccaatcc gtagccaacg ataaaatcat
      481 tcggtatttc catcgctacg tattctatgt tcagattgac cttcagcttt tccggtttca
      541 ccagcaaaga ggcgatatga atcgcttcgg ggttgcgtgt gcccagtgta tccagcagac
      601 gctgcatcgt cagtccggta tctacaatat cttctacgat cactaccgta cgtccggcaa
      661 tgtcttcatt cagcccgatc acttctttaa ttactccggt ggaagtcacc ccctgataag
      721 atgccaactt cacgaatgaa atttcgcacg gaatcgtaat atgcttcagc aagtcggcgg
      781 taaacatgaa cgagccgttc aacacactga ggaagagcgg attcttacct gccaaatcac
      841 gattgatttc gttcgctacg cgaatcactt ctttctgaat atcctgttcc ttaatggaaa
      901 cagtaaattg cttgtctttt atctgtatgg tatccataac cggtcatttt aaaaaagttg
      961 tcgcaaaaat acaatttttt attctacccc gtgcatcatc ttctgtaatt tcttcgagag
     1021 aaggaacaga atcagtgagg caacaccgga cataatgacg aacagcatga agaagtcgta
     1081 catggtagcg atctgataac caaggattga tttcactttt ccgtcttcgg gatagaggcc
     1141 gctcagcata cctgcaaatt tatttgcggt ggcggtagaa agataccaga tccccatcat
     1201 caaggaggcg aaacgtaacg gactcaactt attaaccata gaaagcccga taggtgacag
     1261 agcgatttct cccattgtat gaataaagta aagccctgtc agccagatca tgctcacctt
     1321 tactcctgga atagcatctt tcactccaaa acagatgaag agataaccaa gagaaagcag
     1381 taacagaccg attgcctgtt tggtagggga agccggttcc atgtttcgct tattcagaaa
     1441 gccccatata ccgggcataa tataggcaag gatcactaca aaaagcggat tgaatgactg
     1501 gaaccacgaa gccggcatct cccagccgaa aatgctgcgg tcagtctgtt cggaagcgaa
     1561 taatgtcaga gaagctcctg cctgctcgta agctgcccag aagaaaatga cgaagaaagc
     1621 tacgatatag attacgaaaa tacggctacg ttctactttg gtcaatgaac catccagcag
     1681 aatgagcact ggaaagacaa tacaagccgt aaagataccc acactaatcc agtcatcgct
     1741 aaaggcatag ctaaaaaaag ctattaaggc aactgtaagg gcagtaatga tgatgatatt
     1801 acgtactttg gtacgtttgt ccatcttcgg atgtgaaata tgttcggctt tatcctcctt
     1861 tttttcacgt ctggcgtcgg ggacgatacc aatcggttca ccggaaggag agaaaaggta
     1921 tttattcttc tgagtttcaa agaggacaac agtgaacagc gtcatgattc cggatgcgag
     1981 gaatccccat ttaaagtcct gcggattccc tgtgtctccc aagaaaccgc aaatcaaagg
     2041 agcagcgaaa gaacctacat taacacccat atagaaaatg gtgtatgcag catccaaccg
     2101 tttgtccccg ggttcatata attgcccgac gagcgaagaa acggtaggct taaagcaacc
     2161 gttacctaaa atcatgaatc cgagcccgcc atacatcagc cagtgggcaa ggtctgtatt
     2221 gttcagtgaa gaggcactca taaacatcag gaactgaccg actgccatca tcaccgctcc
     2281 ccaaaatacc gaacgacgga tgccccaata tttatcggca atgtatccgc cgatcaacgg
     2341 agtcagatag accagtccgg tgtagctacc gtagatagag gccgccgctt ctttatcaaa
     2401 aagcaatgcc tgcgtcagaa agaggataaa gatagcacgc ataccgtagt aactgaaacg
     2461 ttctgccgtg ctcgttgcga aaattaggta aaggcctttc gggtgccctt tcaatgaact
     2521 catgaattat gtgtttagta gtttatgggg tgcaaaggta ctaaaaagta gattaaatgc
     2581 ctcaaaaaag aagattctta tggaatagaa aaatacagga tggcgtgcaa gaagtctcag
     2641 ttacccacct tattatgttt tcaacagtgt aaataatcaa gtggatattc tccttaaatg
     2701 tgggtcagtc cccatttatc caaaggtaaa ttcaacattc tcaatactgg catagagcat
     2761 tccttctttt tttctaagca ggattttgtt ttcccttgcc agccaaccga tagcaatcgc
     2821 tacatcctcg aacgtcaaac ctaactcatg gcacaaagtg aacatagact gttcgccctt
     2881 ttcatttaag atgcgccata ctttcccggc atttgagcca attcttttct tttccatcat
     2941 gcaaacttta gaagattaaa caatttatat ttataatcta aacattgtga gcacaggaga
     3001 ataacgtaaa gcacattact gcactacaaa gatatcattt ttctcgaaaa aagcaaataa
     3061 tcaaagcatt agctgctatt attagttaca ttctaatcat ttatgccgat ctctgctaaa
     3121 aaatagcaca aataaagaaa cagttcaatt ctttttcata agtttgcaga cgagaactaa
     3181 actaatatcg cacatttaaa actttaatta gcatgactac caaaaaacta acaggaatac
     3241 tttcgttatt tctttgtatt atttgcctcg tgagctgtaa tgacaatgat gacaactttt
     3301 ctccaatcac tctggaatat gaagatcctc aaattaagtt cgacaacgag agccgttctt
     3361 acacactgac tccgttcagc aaagaaacga caccactctt catcaagggt ggagaccgaa
     3421 cttacaaagt gaccaatgag aatgagaaag tggtacaagt aaactaccac aacggaagtt
     3481 taacattgaa ggcaaaggaa ataggacgcg catccatcaa gatagaagac agttcgaata
     3541 atatgtatat actgtctgtc gttgtaaaat atcgtactct tactcataag gcgtttacag
     3601 caaaagtcat tgtgaaggga gacgagctta catctgaaga acacactgag ttaatgaaca
     3661 aagtgggcaa ttcatatccg attaataaat atgtatttac ttttatgaat gcggaagaca
     3721 gcaaaggaac agtagatttg tattattcag ataataacat gaaaacaggc aactttgaaa
     3781 aagaacatat agtgctggat gaagaaaatg ccattcccat caaaggtgaa tacaaattga
     3841 gtgagtatta ccgtataaca atcaaagaag ataatggcaa agttattgat actttctata
     3901 ttaccaagaa ctttctacca ctcctcaata caagaatgaa tgctcatccg ttaattcagt
     3961 actgttttgt cagagattta accgcacagt acaaacaaga ttaccttgca ctggaaaatg
     4021 catatctgat tcaaatagca gaatgagaac tacactgatt ttcttcttta gcagagtgaa
     4081 tagagtattt attatatgag caaactcccc attagattta gcaaaaaaca ataagctatt
     4141 agctaatcaa gaatatgccc atagcatatt tatcacaatc acctcttcca cccttttcct
     4201 gaacctttga tgaataaggc gattgcgggt gaaagaggtg aaccagagga atatacagta
     4261 gtagaaacac gcatgggaag gttaacaaac agccatgaat gttctccgga gagagtaaaa
     4321 gtaaatgaga taacaatcat taatatctga cttctcaact attaataact gacacatcaa
     4381 ctattaatac ctgacaactc aagtattaat acctgaagtt ccttcccaaa aagccgaaaa
     4441 ccaaccggaa taaaggatta attcagagtt tttgtgtaag tttgtgcgtc gaaaactaaa
     4501 agaatatcgc aatgaaaata tttccaagca gcagcattaa gaagttagat gcctatacca
     4561 ttgaacatga accgattgca tccatagatt taatggaacg tgccgcacag gcgctgacta
     4621 aagccatcac caacagatgg aatccggaaa cacctgtcac catctttgcc ggaccgggaa
     4681 ataatggcgg agacgccctc gccatcgccc gcatgatggc ggaaaaagga tacaagatcg
     4741 aagtatatct cttcaacacg aaaggcgaac tttcgcccga ctgtcagacc aacaaagaac
     4801 tggtagagat gatggaagaa gtaactttcc atgaaatcag cacccagttc gtacctccca
     4861 cactgacacc ggaacatctc gtgatcgacg gattattcgg ttccggactc aacaaaccat
     4921 tgagcggagg attcgctgcc gttgtgaaat atatcaatgc ctctcccgcc atggtagtct
     4981 ccatcgacat cccttccgga ctgatgggag aagaaaatac attcaatgta aaaagcaata
     5041 ttatccgtgc ggacgtcact ttcagcctgc aacttcctaa actggccttc ctctttgccg
     5101 aaaatacaga atttgttggc gaatgggagt tattggacat ccagctgagc gaagaaggaa
     5161 tcgaagagac tgaaacaaac tacgaaatgc tggaaatcga agaaatccgt tcactgatca
     5221 aaccacgcca acaattcgcc cataaaggaa acttcggaca tgccctgctg atagccggct
     5281 caaaaggaat ggcaggtgca tcggtactgg ccgcccgtgc ctgtctgcga tcgggagtag
     5341 gtctgctgac ggtacacgcg ccgttatgca acaacgatat tctgcaaacg tccgcccccg
     5401 aagccatggt agaaacagat gtcagcgaaa catgctttgc cgtacctacc gatacggacg
     5461 attaccaagc tgtcggcatc ggtccgggac tcggtcgcaa cgaagaaacg gaagccgccc
     5521 tgatagaaca actggaacat tgtcagactc cgacggtact ggatgccgac gcactcaata
     5581 ttctggccaa tcaccggcat acgctcaccc atctgccgaa aggttccatc ctcacccctc
     5641 acccgaaaga gctggaacgc ctggtcggca aatgtcagga ctcatacgaa cgactgatga
     5701 aagcctgcga actggcgcac actgccaaag tacatatcat tctgaaggga gcttattccg
     5761 ccattatcac ccccgaaggc aaatgttact tcaaccagac cggtaatccc ggtatggcaa
     5821 caggaggcag cggagatgta ctgacaggag taatccttgc actccttgcg caaggctatc
     5881 ccgccgaaga cgccgcaaag atcggtactt acattcacgg attggccgga gacatcgccc
     5941 agaaaaaaca gggcatgatc ggattaatcg caagtgatat cgtgacttgt ctgccgacgg
     6001 catggcgact tgtaagcgaa taaaagttaa gaacttacgg tttattcaat aacttcatta
     6061 actttgtttt tcaaaatcag ctaaaaagaa ccgaatatga aaaagttaat catagcaaca
     6121 ggactactaa tggcaacttc cgcctatgcg cagaccgaag tgctgacagg agtgacgcga
     6181 ggaaaagact acggagtagt gtacgccctc cccaaaaccc agatagaaat agaaataaaa
     6241 gcaaacaaag tcaactataa gccgggtgaa ttcagcaaat acgccgaccg ctacctgaga
     6301 ctgaccaacg tctctgccga acccgaagaa tactgggaac tgaacagtgt caaagtgaaa
     6361 cctgtaggtg taccaaacag cgaagctact tatttcgtca aactgaaaga caaaaccgta
     6421 gctcctctta tggaactgac tgaagagggt cttatcaaat caatcaatgt cccctacagc
     6481 agtaacaatg caaagaatgc agcaaacaat gccgttgctc cccaacgaaa agccaatccc
     6541 cgcgactttc tcacagaaga aattctgatg gcaagttcaa ccgccaagat ggccgaactg
     6601 gtagcaaagg aaatctataa tatccgcgaa agtaaaaacg cattattgcg cggacaagca
     6661 gataatatgc cttcggacgg cgcacagctc aaaatcatgc tcgacaacct gaatcttcag
     6721 gaagaagcca tgaccgagat gttttcggga gtccgcaata aagaagaaaa gacatttact
     6781 gtccgcctca ctccggataa ggaattcgac aatgaggtag ctttccgctt ttcaaagaag
     6841 ctgggtatag ttgccaacaa cgatttggca ggcactccat tctacatcag tctgaaagac
     6901 ctgaaaacgg tgaagattcc gcaagaggac gggaaaaaga agaaagagat ggaaggcatt
     6961 gcttataacg taccgggaca ggcaatggtg acgctgacgg acggcaaaaa gaaattgtat
     7021 gaaggagaaa tacctgttac tcagttcggt atcatagaat accttgctcc ggtattattc
     7081 aacaagaact cgaccatcaa agtttacttt gatccggtga ccggtggact actgaaagta
     7141 gatagagaag aaagcaaata aaacctctaa aaaaacaaaa cgatgggtgg cgaaggacat
     7201 atgctcgaca tgatacgtcg gctgaaagac ggcaaagaag cctcccgctt acgccgtgaa
     7261 cggagaaatg acaagttagg gcgacttaga agaaacaacg acccttatct tctgccggat
     7321 acgactccgg aagagatgga acgcatcatc aaggattcgg aaaagaaaaa agaaaaagat
     7381 aacagctatt tcgtatgggg aacgcttatc attatgggcg tactgatagg atgtgctgtc
     7441 ctcctgtggg caatcttttt taatggataa ttatccattt aataaatccg tctttctgta
     7501 attgggaaag ataggtagat acacgagact cgtagcctgc ttcatattga aagtggtctg
     7561 cgagtttttc tataatctca cgaaccgtcc gctgcccgtc tatcaggttc catacggccg
     7621 taccgtgttc ttccagacgc acatgaatat ctttggacat tcctttcggc aataaataac
     7681 gactcatcca cgaacgttta aaacgaggga aggagagcac aatagtctcc ccttcctgtt
     7741 cagctttaat atgttcgtta cgacaaggta tcacctccag gaggtttatt ttctctttcg
     7801 tagccatatc ttttctcttt tatatctttt cagatagaat atatactgtg attatttctg
     7861 aatatttgct tcttccagtc cgtagccttt cttcttgttt tccactttca gcatcaaggc
     7921 aacaatcagg gcaagtacac cgaacatagc aaaaatagcc atcggcaagg tataatcata
     7981 agtctgtgca ccatctacaa ccggaccttt gcaataagag ttcaacaccc atccgatcag
     8041 caaaggcacg cccatcaatc cccagttctg tacccaaaag atcaacgcat aagccgttcc
     8101 caactgtttc tccggaataa tcttcggaac cgaaggccac attgccgaag gaaccaatga
     8161 gaaagcaaat cccagaataa tcatgatcac cgttgcaaac caccatatat tcagaatagg
     8221 aagagcgaac atcgtgtgta cgaaaatcag catcaccgac ccgatcacca tcagcgtggc
     8281 tcccttaccg atacggtcat acaatgaacc gaacaacggt gtcaggatga tcgcgccaat
     8341 cggcagcaat ccgggaatcg ttcccgcaag tttcggatca acattgtact tctgtaccat
     8401 caaatcggcc gcatacttga tgaaggggaa tacagccgaa tagaacaata cgcacagtaa
     8461 tgcgatcagc cagaatcctt tgttggtaat gatatagaca atgtctttca tgcggaaagg
     8521 ttcttccggt tccagtcctt ccgcatccag tgaagcatcc agtttcttat cgtagaaagt
     8581 atagatgaag aatgcgatgg tacctacgca caacatgacg agacagaaca gaatcggagc
     8641 gggaatattg gtatggaata cgccgctctc atccgtagac ccgaagaagt ctgccaaagg
     8701 aacggtaagc accatggcca aagtcgttcc aatacgcgcg gtcgccattt ccagtcccat
     8761 agcgagagcc atctctttgc ctttaaacca cttcacgata atcttcgaaa cggtgatacc
     8821 cgcaatttcg actcctacac cgaaaatagc ataacccaat gcagccaatg tgacttgcat
     8881 cttgaatccg aaaagcatcg caccttccgg gaaagtagta gtaatagcat aatatttcaa
     8941 tccacaaccg aacaccatca ataaacaggc acccattccg gtgaagcgta ctcccatctt
     9001 atccagaatg ataccaccaa agatgagcat cagcaggaat acattaaacc agccataagc
     9061 actggtgaaa aaaccgtaat ctaaactgtc ccagagaagt tctttttcaa gcatgggttt
     9121 cagaggagac ataacgtctg tgaggaagta gccgcacaac atggtaaaag cgactaatgc
     9181 tagaacactc caacgcagca ctgcggagtc attcagcttt tgtttcaatt gttctgtcat
     9241 tgtaatattt aaaaggagtt aataatctcg taacgggcaa caaagttaac taattatcat
     9301 ttgttttact aaaaaaggag aacattttat aagaaaaagg acatctgacc ggatattcct
     9361 gtatgaagaa gagcagaccg ggcccaataa taaagacagg cgcgaactac acgtattaca
     9421 cgattctatt agaatctctt gtaattcgcg taattcgcgc ctataatgaa gagaacgggt
     9481 caaaaagccc gttcactcaa taagtttaaa ccgaatatcc tgtcactgaa ttattctgct
     9541 gcaggagcag gagtttcagt agccgaagct tccgttgctg gtgcagactc tgcaggagca
     9601 gtagcatctg tctgaggagc agcagtaccg gtaggcatat tatacgggtt ggtttgttgt
     9661 tctttctgtg cttgttccaa caatacatct ttagccgcag aagaagaagg aacaacgtaa
     9721 gcagtagcaa cgctcatcac aaccatgaag atagccagac cccaagttgc tttttccaga
     9781 aaatctgtag tcttgcgcac gcccatgata gcgtttgatg aagaaaaacc agaagcaagt
     9841 ccgcctcctt ttgaattctg aatcagcacg atgaagcaca tcagcaaggc tgcaatcacc
     9901 attaagataa tgaataataa gtacattttt agttattttg aattagcgtt aataatcaat
     9961 ttctcnnnnn nnnnnagcat ttttttttgg atatttcaag cttaattttt taattatttc
    10021 aagagctttc gaatatcgtt gctgttttac gtagattttg gccaaagttt ctgtgaaaca
    10081 gctgtcatct tcctcttcta tggtgttggt ttcagttgtt tcgtctgttc tgcccgtttc
    10141 gtttgtttca gcggaagaag ctgcctttgc tttctcttct tccctcaaag gtttcaggta
    10201 tacgactgga tcagtctcgc ttttttcgat aaagttgtca atcagctcgt gtcctttcag
    10261 cttgggcatt gcctctgccg gctcgtcggc gacaggtgtc tcttcgagaa ggtatgccgt
    10321 atagtccata gagtaatcaa agcttgtctg actggttact tcttcgggag ccgtcgaaag
    10381 gaaagcatcg atcagagcca gtgtccggtc gacggtaggc tcatctttca atacttcaga
    10441 gagaggcaac cctttcttct gggattcgac agcgaagcgt tcgccttcga tcagatgaaa
    10501 cagtttccgt cggtcggcaa tatacagaac ggctttccgc agttccgcac cgaaattaat
    10561 gtcgtggaga atatacaggt tcttgagata caacaaccgg agcgactgaa aatacggata
    10621 cctcgcgagc tggttgcgca gttcgtacaa agtatcccta ttcagcgtct cgggatgctg
    10681 aatccatt
//
