LOCUS       gnlProkkaEHLLENFJ_117  10706 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EHLLENFJ_117.
ACCESSION   gnlProkkaEHLLENFJ_117
VERSION     gnlProkkaEHLLENFJ_117
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:32:25
            Original ID  :: gnl|Prokka|EHLLENFJ_117
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10706
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10706
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3855:8169]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3856..8169
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10706
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10706
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..206
                     /locus_tag="ctg117_1"
                     /transl_table=11
                     /translation="MPEQDATLCLAILQGYNVSMYANPEDEDRKRSVLQRSLTLLDALP
                     PSLLKQQLSAVCHGMQELCETN"
     CDS             222..2633
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg117_2"
                     /sec_met_domain="Poly_export (E-value: 5.8e-18, bitscore:
                     54.2, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCSMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSQSTGTDINESRLREETKENTSDMLED
                     HPTTEDLAREDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPDDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             2644..3792
                     /locus_tag="ctg117_3"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             3856..4575
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-16, bitscore:
                     50.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEYDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             4596..5897
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.5e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.6e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.8e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             5914..7038
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.4e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.2e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             7048..8169
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg117_7_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_7"
                     /sec_met_domain="Aminotran_5 (E-value: 1.2e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        7138..8145
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg117_7_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg117_7_Aminotran_5.1"
                     /locus_tag="ctg117_7"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             8166..8309
                     /locus_tag="ctg117_8"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             8512..9996
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_9"
                     /sec_met_domain="Polysacc_synt (E-value: 1.1e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             9950..10705
                     /locus_tag="ctg117_10"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKISFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIGEFYQFNLSSCIRQQN"
ORIGIN
        1 agacaccgga gcaggatgct accctgtgtt tggccatcct tcagggatat aatgtgtcga
       61 tgtacgccaa tccggaagac gaggatagaa aacggtctgt cttgcagcgt tctctgaccc
      121 ttcttgatgc tcttccccct tctcttctta aacaacagtt gtctgccgtc tgtcacggta
      181 tgcaggaact gtgtgaaacc aactaacttt tttatttgtc aatgaaaata caacgacttt
      241 ttagcattct acttttttgt tctatgctgg gaagtggctc gcttatggcc cagtccatga
      301 gtgactcaca ggtactggaa tatgtaaagg acggcatccg gcaaggcaag gaacagaaac
      361 agcttgcttc cgagcttgcg cgtaaaggtg tgaccaagga acaggctatg cgtgtgaagc
      421 agctctatga gcagcagaat aatgtaaaca cctcccaatc cacaggtacg gatatcaacg
      481 agtcccgcct tcgtgaagaa acaaaggaga atacttccga catgctggag gatcatccga
      541 ctacggaaga tttggcccgt gaggaccagg ttttcgggcg caacatcttc aatacccgca
      601 acctgacgtt cgagcctagt gtcaaccttg ccactcctgc caattaccgt cttggtcccg
      661 atgatgaagt catcattgat atctggggtg cgagccagaa cacgatccgc cagcaaatct
      721 ctcctgaagg tactatcaac attcagaaga tcgggcctgt caaccttagc ggtatgacag
      781 tctctgccgc caatgactat ctgaagaacg ccctgaataa aatatataac ggtctgaata
      841 atactaccga tcctacttcc gacatccgtc tgacgttagg taatatccgt actattcaga
      901 ttaatgtgat gggagaagtc gtacagcccg gtacctacgc cctttcttcc ttctctaccg
      961 tcttccatgc gctttatcgt gcaggcggtg tgagtgatat cggtagcctc cgaaacgttc
     1021 agttggtacg caacggaaag aatattgcca ccatcgacgt ctacgaattc attatgaaag
     1081 gcaacacaca ggatgacatc cgcctacagg aaggtgacgt tgtgattgtt cctgcctatg
     1141 atgtattggt aaagattagc ggcaaggtaa aacgtcctat gcgttttgaa atgaagaaag
     1201 acgagaacct tgctactctc attaaatatg ccggcggctt tgaagctgat gcctacaccc
     1261 gttcattacg tgttgtccgt cagaatggtg aggaatacga agtcaacaca gtcaaagata
     1321 tagattacaa catttataaa atgcgtaacg gtgacgtagt aaccgccgaa gccatcctta
     1381 accgcttcac aaacaaactg gaaatccgtg gcgctgtcta tcgtcccggt atctaccagc
     1441 tcagcggtaa actgaacacg atccgcgaac ttgtccatga agctcagggt ctgaccggtg
     1501 acgctttcct gaatcgtgcc gtcctctatc gccagcgtga agacctgacc agtgaagttg
     1561 ttcagataga cattaagtct atcatggacg gcacttcccc aaaccttgcc ctaatgaaga
     1621 atgacatcct ctacattcca agtatccatg acctggaaga ccggggtaat gtcacagttc
     1681 acggtgaggt tgcccaccct gattcctatc cttatgcgga taacatgaca cttgaggatc
     1741 tgatcattca ggccggtggc ttgaaagaag ccgcctctac tgtccgtatt gatatatcga
     1801 gacgaatcaa gaatcctcgt agtactgcgg ataatgatac gattggtcag atgtatacct
     1861 tctctttaaa ggatggtttt gtaatagatg gtcagcccgg ttttatcctt gagccttatg
     1921 atcaggttta tgtccgtcgc agtccgggct atcaggcaca acagaatgta gccattgaag
     1981 gtgaaatcct tttcggagga aattacgcca tgaccagccg tgaggaacgt ctttccgatt
     2041 tagtgaataa agccggcggt ccgaccaatt atgcctatct gcgtggtgcg aaactgaccc
     2101 gtgtggctaa cgctagtgaa aagaaacgta tgggtgatgt aattcgcctt atgagcaggc
     2161 aattgggcga agccatgatt gactctttgg gtattcgtgt tgaagatact tttacggttg
     2221 gaatagattt ggaaaaagcc ttgagcaatc ctaaaagtaa tgccgatctt gtcttacgtg
     2281 aaggtgatgt gatctccata cctaagaata ctaatactgt aactatcaat ggtgctgtca
     2341 tggttccgaa tacggtttct tatatgaagg gaaagaatgt ggattattac ctgaatcagg
     2401 ccggtggctg ttctgataat gcaaggaaga gtaagaagtt cattgtttac atgaatggtc
     2461 aggtgacgaa ggttaagggt agtggtaaga aacagattga gccggggtgt gagattattg
     2521 tgcctggtaa ggctaagaag aaagggaaca tagctaatat tttaggttat gctacttcct
     2581 tcagttcttt gggaatgatg attgcttcta ttgctaattt gataaagaaa taaatgacct
     2641 attatgattg aaaagcaatc ttatcaagaa ccgttttctg aagtggataa aaggaaagat
     2701 gatgaaatgg aaatagactt gatggctatt ttttataaga ttattactgt tcgtggagta
     2761 ctatgcaaag ctgctggagt gggagtaata attgctatag tggtggcatt gagcattccc
     2821 aagcaatata cagtaaaggt taccctttct cctgaaatgg gtaatgcgaa gggaagtaat
     2881 ggtttagccg gacttgctgc ctcgtttttg ggagatgggg ctctaatagg ggaaagcaca
     2941 gatgccttga acgcttctct ttcagcagat attgtttctt caactccttt tttattggaa
     3001 cttttagaaa tggaagtctc cgtttctaaa aaggatgata aaatgacttt ggggtcttat
     3061 ctcgatgaag agtcatctcc ttggtgggat tatcttatag gttttccggg catagtaata
     3121 ggaggagtta aatcattatt cggagaagat acggttcctg ccagtggagg gcggcaagga
     3181 actatcgaat tgacgaaaga agtaaatgag aagattaatt ttcttaaaaa gaagattagt
     3241 gcatccattg ataagaaaac cgccataacg agcattacgg tcaccttaca aaatccgcag
     3301 atcactgcgg ttatagcaga ttctgtcgtt cataaattac aggaatatat tattgggtat
     3361 cgaacttcaa aagtaaaaga agactgtgcg tatttggaac ggttgtttaa agaacgtcag
     3421 caggaatatt atgctgctca aagaaaatat gcggattatg tagacgccca tgataatgtg
     3481 gttcttcaaa gtgtacgtgc tgagcaggag cgtttacaga acgacatgag tttggcttat
     3541 cagatatata gtcaggttgc taatcagttg caggtatcca gagccaaagt acaggaggaa
     3601 aagccagtct ttgcagtagt tgagcctgcc gttgtacctt tgaaaccttc aggtatggga
     3661 ctcaaaattt atattttatt atttgtgttc ctgtccgtat ctggtactct cgtgtgggtg
     3721 ttttttggca aaagtctgct ggctagcttg agaaaagaac tgaaaaataa ggagatagaa
     3781 caggataaat gatgctaaaa cgtcgtttac aacattctta catcaattaa attcacttac
     3841 tatattatta aacgaatgat acgtacagct atgataatgg ctgcgggcat gggaacccgt
     3901 tttggccaat atacagaatt gatacctaaa gggttcgtca aagtgggagg tattccaatg
     3961 atagttcgtt ctattgatac tttgttatca tgtgacattg agcgaattgt aatcggtaca
     4021 ggatataaac aagaagttta tgaagaattg aagacagact atcctatgct tgaaacctgt
     4081 tttagtcctc gttatgctga aacaaatagt atgtatactt tatataatac gcgggagatt
     4141 ctgggcaatg atgatttttt attgttagag tcagatttga tttttgagaa acaagcaata
     4201 atgagcttat tggagtgtcc tgcggcagat gcaatgctaa taactccagt gacaaagttt
     4261 caagatcagt attatgtgga atatgatgat aattttcgcc tttcttcatg ttctgtcaat
     4321 aagaataaac taaacgctaa aggcgaattg gtcggcatcc ataaactatc cggttccttt
     4381 tacaaaataa tgtgtgctga ttatgcgagt attgttgatg aacaacccaa tttgggatat
     4441 gagtatgaat tactacgaat atcttgttct caatctcctg tttatgtgca taaagtagaa
     4501 gggctgaaat ggtatgaaat cgatgacata tcagatttgg aatatgcaga gaaatatatt
     4561 gttccgtatt gttaattaaa ataatatatc aaattatgag taagacagtt tatattggga
     4621 tgactgcgga tattatgcat ccaggactta tccgcattat taatgaggct actaaatacg
     4681 gtgatgttat aattggtctt cttacagata aagctattgc ggagcataaa cgccttcctt
     4741 atctgaccta tgaacaacga aaagaggtag ttcagaatat taaaggcgta tgtaaagttg
     4801 ttcctcaaga agaatggagc tatgttgaga atctcaaacg cattaaacct gactatataa
     4861 ttcatggtga cgactggaaa accgggcctt tacgtgaaga acgtgtgcgc gtatttgaag
     4921 tgatgaatga acagggagga aaggttatcg aaattccata tactttggga attaattcat
     4981 cttctttgga taaagatatt aaggctatag gtacaacccc tgatgtacgt ttaaaatcac
     5041 ttcgtcgttt gataaatgcc aaacccgtag ttcgtatttt ggaagctcat gatggactat
     5101 gtggcttgat aattgaaaat caggaaatat taaaagggga taagagggaa gtatttgacg
     5161 gaatgtggtc tagtagcctt acggattcaa ccagtaaagg taaacctgat attgaggcgg
     5221 ttgatttaac tacccgattg caagatttga ataatattct ggagtgtact actaaaccta
     5281 ttatttttga tggagataca ggtggtaaaa ttgaacattt cgtatttaca gtacgcactt
     5341 tagaacgtca tggaatttca gctataataa ttgaagataa agttggatta aaaaagaatt
     5401 cattgtttgg tacagatgtt attcaaactc aagatacaat cgaaggtttc tgtaataaga
     5461 tcaaagcagg aaaggcatct cagattactg atgattttat gattatcgct cgtattgaga
     5521 gccttatagc gggaaagccg gtaagtgatg ctttagagag agcttttgca tatgtccaag
     5581 cgggagcgga cggtattatg atacatagca aaaataagtc gggtgaagat ataaaagaat
     5641 tttgtttggc gtttcgaaaa cagtatgctc atgtacctat cgtggttgtg cctactacat
     5701 atgatcatat ttatgagtct gaattgtgtg attggggtgt gaatataatt atttatgcta
     5761 atcatatgct tcgtgccgct tatcctgcta tgatgaatgt cgcaaagata atattagaga
     5821 atgaacgtgc tttagaggtg cgcgaactgt gtatgcccat aaaagaaata ttggaactga
     5881 ttccaggtac taaataaaaa gaggaatatc attatgttaa gcgtagaaaa agtttatgaa
     5941 acgtttctga gtcatgacgt tgattttttt acaggagttc cagactcatt actaaaaaat
     6001 atttgtgcct atatcacaga ccatacttca cgtgagaaac atatcatagc tgctaatgaa
     6061 ggtgcggctg taggaattgc ttcaggttat tatatggcat caggtaaggt tcctgtggtt
     6121 tatatgcaaa attccggctt gggtaatact gttaatcctc tgctgtctct tgcagatgaa
     6181 caagtataca gttttccaat gcttttgatg attggctggc gtggtgaacc gggaacaaaa
     6241 gatgaacctc agcataaaaa acagggtgag gtaactttag atttgttgaa agcaatgcgg
     6301 attccttata taattcttga ttcaaatgag aatgatgcat ttattcagct ccatgatatc
     6361 atacaatcag caaaaactaa gaatattcct catgcaataa ttattcggaa agatgttttt
     6421 ggcaaatata aacttcaaaa agagttcgga tgtaattatc ctttatctcg tgaggatgct
     6481 ttgcaaatag ttgtggatta tctgcctgaa aattcagtgg tcgtttctac tactggcaag
     6541 ctttctcgtg agttatttga atatcgagaa atgaaagagc aaggtcatga acatgatttt
     6601 ctcacggtag gctctatggg acatagttca tcaatctctt tgggtattgc tatagcaaag
     6661 caagatagac ctgtttattg cttggatggt gatggagcat ttattatgca tttaggggca
     6721 attagtaaca ttggcgattt atctcctaaa aactattatc atattttgtt taacaatggt
     6781 gctcacgagt ctgtaggagg acagcctact ttaggattta gtttagatat tccggctatt
     6841 gtccggggga gcggatataa gcatacttat actgtttgta caaaagttga aattgaagaa
     6901 gcaatgaagc agcttccaaa gttatgtggt cctgttttgt tggaaataaa ggttaaaata
     6961 gattctcggg agaatttggg acgtcccacg actactccta tagagaataa ggagcatttt
     7021 atggattttt taaaataaat atattcgatg aaaatagaaa gaaaaatatt attaaatcct
     7081 gggcctgcca ctactactga cagtgtaaaa atggcacaag ttgttccgga tatttgtcct
     7141 cgcgagaaag aattcgcagg tatgatgaaa caacttcggg acgatttggt cagagttgct
     7201 catgggaatt tggaaaaaca taccgctgta ttattttgtg gctcaggaac catcaatatt
     7261 gatatatgtc taaattctct tcttcctgaa gacaaaaggg tgcttatagt gaataatggg
     7321 gcatatagta cccgtgctgt agaagtgtgt caatattatg gtttgcctca tattaatttg
     7381 gaattttccg tttacgaacg tcctgattta tcggtggtgg aaaatgtgtt gcaagaaaat
     7441 cctgatatag ctatggttta tactactcat cacgagacgg gtacaggaat tctgaaccct
     7501 attcgcgaga tgggcgctat agctcataaa tatcaggcta aatttgtcgt cgatactact
     7561 tcttctttgg gcatgattcc ttttgatata gagaaagata atgtggattt ttgtatggca
     7621 tctgctcaaa aaggacttca agcgatgaca ggtctttctt ttattatagg caatgaggaa
     7681 cagattaagt tttcaaaaaa atatcccaag cgttcttact attgtaatct ttatttgcag
     7741 tatgagaatt ttgagagaac aggtgaaatg cattttactc caccggtaca aactatttac
     7801 gccactcgtc aggcattaaa tgaatatttt gaagtgggtg aagaagctaa gtttgcccgt
     7861 cacaaaagag tttttgaggc tattcattca ggtataaatg aaattggtct taaaagtgta
     7921 ataaagcgtg aatggcagtc aggactggtt gtctcagttc aatacccaga agatcccaac
     7981 tgggattttg agaaaataca tgattattgt tatgagcgtg gatttacgat ttatccaggt
     8041 aagatatcaa ctgaggatac ttttagaatc tgtgctttag gagagataga agtagatgat
     8101 attgagaact tctttaaagt actaaaagct gcattaaatc attataacgt cacattaccg
     8161 atgtcatgat tgcagaaata ttattgaaga ttcgtcattt ttatttttcc cttcgtggta
     8221 tacacttcca tccggaaagt gttatttctg gagtgcctat tcgtagcttt cgcttagtag
     8281 gcaaatatgg caatattaat ttgaggtgat gcattaggag ttctttattc ttataaaaag
     8341 gcatcggtag ttataggaga taatgtttgt gtagggtaat ttgcttttag tgggagagac
     8401 catattagaa ttgcggtaag gggcgaagaa gataataacc aattagtgag aatattggaa
     8461 aaatataatt gatatcggta aatgtagttg tttttatact gtatttaagt aatggaaaat
     8521 ctaaagcaga aaactgtatc aggaataatg tggagcgcta tagaacgttt ctctttacaa
     8581 ggagtacagt ttataattca aataatatta gctcgtttgt tactaccatc ggattatggt
     8641 atgatcggga tgttagctat ttttcttcaa gtcgctcaag tatttataga tagcggtttt
     8701 acaaatgctt taatccagaa aaaagataga actgaagagg attttgccac tgtcttttat
     8761 tttaatattc ttgtcgcagt attattctat ggtatattgt ttttttcggc ttctttgatt
     8821 gcagactttt ataatatgcc gactttagtt cttgtaattc gttttatagc attgtcgttg
     8881 ataataaatg ctttatcggc tattcacaga acgaaattaa ttatttctgt aaactttaaa
     8941 actcaatcta aaatttcatt aggtgcagct tttatatcag gcgtgattgg aatatggatg
     9001 gcttatgtcg gttgcggggt ttgggcttta gtttggcaaa ctctcttaaa tagtataatt
     9061 ttgacaattt tgttttactg tttagttcat tggaaacctt tacatacttt ctccaaaagt
     9121 tcttttgaaa gattattcaa tttcggatct aaattattga tctcaagtct tatcaataca
     9181 gtatatcgta atctgtatac cattgtaata ggaaaaaagt tttctgttgt agagcttggt
     9241 tactatacaa gagcagaaca atttgctatt tttccttcca ataatttaaa tgctttagtt
     9301 tctagagtag cgtatcctat tttaagttcc attcaagatg atgataaatg tttaacaaac
     9361 gcatatcgaa attatatcag attatcctca tatataattt ttcctttaat ggtaggttta
     9421 cttgttttgg ctaatcctat tattagtcta ttgttaacag ataaatggtc tggggttgtt
     9481 attcttttac agatattatg tttggattgg atgtttgatc atttgagcca aattaatttg
     9541 aatttattat gggttaaagg aagatctgat ctgtcgttac gtcttgaaat aataaaaaag
     9601 acgattgcta tattcattct ttttgtgtca attccatttg ggcttgaggt gatgtgttgg
     9661 ggtagagtta tttactctct gatagcgaca tatttgaata catattatac taattctctt
     9721 attgatttga ccttaaagtt gcaagttaaa gatgtatttc caagtttaat actctctttc
     9781 ataatggggg ggatcgtttt tatatgtatt tctttctttg aaactgatat agtaaaaatt
     9841 gtgattggat gtattactgg gatgtccttc tatattttac tttcttttct ttttaagcta
     9901 gattcttttt tttgtatttt aacattgatc attaaaacta aaaacataga tgaaaatatt
     9961 aaaaaagatt tttcaagtaa tagtaaagat aattaaccat tgtgtgccag ttgatagtag
    10021 atcattgtat tttattcctc atcctaattg tagaacagat aaatatgata ttataaatta
    10081 ttcgtcagat aatgttctcg ttctgttaaa ttatttgcta aaaaaagata gtgctgaata
    10141 ttataaaata tatgttgaaa tttatgattc ttctcgtatt tcagaatatc aagaatatat
    10201 ttatggcata aatcctaata ttaggtgtac ttttttatgt gcatgtgttg gacgtttttt
    10261 ctttaataaa atatctttta aggatatgtt gtatgccttt ttttgttttt gtagagcaag
    10321 taaatgtttt acagctactt tttattatga tttttcattt aaaaaacgct ctcaacagat
    10381 tatttgtttg gggtattata ctccattcaa agatgattat catatgggag atcattctta
    10441 tgataaattt cgtaatacaa catgtaactc atttgattac tctattgcta cttcttgttt
    10501 aagtgctaga ataatttcaa tagattgtgg aatctcatat gataaattca aagtcttagg
    10561 atttcccaga aatgatttgt tgatatcgaa aaataattgc aatgttatta aaagagaaat
    10621 ttcgaaattt gcgggatatg atgtaactaa atatataggt gagttctatc aattcaattt
    10681 atcctcttgt atcagacagc agaact
//
