LOCUS       gnlProkkaEHLLENFJ_35   12507 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EHLLENFJ_35.
ACCESSION   gnlProkkaEHLLENFJ_35
VERSION     gnlProkkaEHLLENFJ_35
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:32:25
            Original ID  :: gnl|Prokka|EHLLENFJ_35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12507
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2159:2507]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2160..2507
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12507
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12507
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             727..2115
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             2160..2507
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_2"
                     /sec_met_domain="PF05402 (E-value: 2.1e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 7.9e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(2497..2784)
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(2806..3870)
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(3944..4780)
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARA
                     CLRSGVGLLTVHAPLCNNDILQTSAPEAIVETDVSETCFAVPTDTDDYQAVGIGPGLGR
                     SEETEAALIEQLEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKC
                     QDSYERLMKACELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGV
                     ILALLAQGYPAEDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             5090..5377
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MLRCQCGRYELGADFMESYFFHHLYQFFVGLAVGRKFAFRVEEIY
                     FDLVSFFRHHAGDGEGVSAIIARSGKDGDRCFRIPSVSDGFSQRLCGTFH"
     CDS             complement(5965..6582)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MTNENEKVVQVNYHNGSLTLKAKEIGRASIKIEDSSNNMYILSVV
                     VKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDL
                     YYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFL
                     PLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             7488..9032
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             9074..9610
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             9644..10213
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             10226..11392
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             11572..12201
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVD
                     ALITREPGYCLCISTADCVPVLVYDKKHGAIAAIHAGWRGTVAYIVRDTLLRMEKEFGT
                     SGEDVVACIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQ
                     ILAFGVPSGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
ORIGIN
        1 ggagaaattg attattaacg ctaattcaaa ataactaaaa atgtacttat tattcattat
       61 cttaatggtg attgcagcct tgctgatgtg cttcatcgtg ctgattcaga attcaaaagg
      121 aggcggactt gcttctggtt tttcttcatc aaacgctatc atgggcgtgc gcaagactac
      181 agattttctg gaaaaagcaa cttggggtct ggctatcttc atggttgtga tgagcgttgc
      241 tactgcttac gttgttcctt cttcttctgc agctaaagat gtattgttgg aacaagcaca
      301 gaaagaacaa caaaccaacc cgtataatat gcctaccggt actgctgctc ctcagacaga
      361 tgctactgct cctgcagagt ctgcaccagc aacggaagct ccggctactg aaactcctgc
      421 tcctgcagca gaataattca gtgacaggat attcggttta aacttattga gtgaacgggc
      481 tttttgaccc gttctcttca ttataggcgc gaattacgcg aattacaaga gattctaata
      541 gaatcgtgta atacgtgtag ttcgcgcctg tctttattat tgggcccggt ctgctcttct
      601 tcatacagga atatccggtc agatgtcctt tttcttataa aatgttctcc ttttttagta
      661 aaacaaatga taattagtta actttgttgc ccgttacgag attattaact ccttttaaat
      721 attacaatga cagaacaatt gaaacaaaag ctgaatgact ccgcagtgct gcgttggagt
      781 gttctagcat tagtcgcttt taccatgttg tgcggctact tcctcacaga cgttatgtct
      841 cctctgaaac ccatgcttga aaaagaactt ctctgggaca gtttagatta cggttttttc
      901 accagtgctt atggctggtt taatgtattc ctgctgatgc tcatctttgg tggtatcatt
      961 ctggataaga tgggagtacg cttcaccgga atgggtgcct gtttattgat ggtgttcggt
     1021 tgtggattga aatattatgc tattactact actttcccgg aaggtgcgat gcttttcgga
     1081 ttcaagatgc aagtcacatt ggctgcattg ggttatgcta ttttcggtgt aggagtcgaa
     1141 attgcgggta tcaccgtttc gaagattatc gtgaagtggt ttaaaggcaa agagatggct
     1201 ctcgctatgg gactggaaat ggcgaccgcg cgtattggaa cgactttggc catggtgctt
     1261 accgttcctt tggcagactt cttcgggtct acggatgaga gcggcgtatt ccataccaat
     1321 attcccgctc cgattctgtt ctgtctcgtc atgttgtgcg taggtaccat cgcattcttc
     1381 atctatactt tctacgataa gaaactggat gcttcactgg atgcggaagg actggaaccg
     1441 gaagaacctt tccgcatgaa agacattgtc tatatcatta ccaacaaagg attctggctg
     1501 atcgcattac tgtgcgtatt gttctattcg gctgtattcc ccttcatcaa gtatgcggcc
     1561 gatttgatgg tacagaagta caatgttgat ccgaaacttg cgggaacgat tcccggattg
     1621 ctgccgattg gcgcgatcat cctgacaccg ttgttcggtt cattgtatga ccgtatcggt
     1681 aagggagcca cgctgatggt gatcgggtcg gtgatgctga ttttcgtaca cacgatgttc
     1741 gctcttccta ttctgaatat atggtggttt gcaacggtga tcatgattat tctgggattt
     1801 gctttctcat tggttccttc ggcaatgtgg ccttcggttc cgaagattat tccggagaaa
     1861 cagttgggaa cggcttatgc gttgatcttt tgggtacaga actggggatt gatgggcgtg
     1921 cctttgctga tcggatgggt gttgaactct tattgcaaag gtccggttgt agatggtgca
     1981 cagacttatg attatacttt gccgatggct atttttgcta tgttcggtgt acttgccctg
     2041 attgttgcct tgatgctgaa agtggaaaac aagaagaaag gctacggact ggaagaagca
     2101 aatattcaga aataatcaca gtatatattc tatctgaaaa gatataaaag agaaaagata
     2161 tggctacgaa agagaaaata aacctcctgg aggtgatccc ttgtcgtaac gaacatatta
     2221 aagctgaaca ggaaggggag actattgtgc tctccttccc tcgttttaaa cgttcgtgga
     2281 tgagtcgtta tttattgccg aaaggaatgt ccaaagatat tcatgtgcgt ctggaagaac
     2341 acggtacggc tgtatggaac ctgatagacg ggcagcggac ggttcgtgag attatagaaa
     2401 aactcgcaga ccactttcaa tatgaagcag gctacgagtc tcgtgtatct acctatcttt
     2461 cccaattaca gaaagacgga tttattaaat ggataattat ccattaaaaa agattgccca
     2521 caagaggaca gcacatccta tcagtacgcc cataatgatg agcgttcccc atacgaaata
     2581 gctgttatct ttttcttttt tcttttccga atccttgatg atgcgttcca tctcttccgg
     2641 agtcgtatcc ggcagaagat aagggtcgtt gtttcttcta agtcgcccta acttgtcatt
     2701 tctccgttca cggcgtaagc gggaggcttc tttgccgtct ttcagccgac gtatcatgtc
     2761 gagcatatgt ccttcgccac ccatcgtttt gtttttttag aggttttatt tgctttcttc
     2821 tctatctact ttcagtagtc caccggtcac cggatcaaag taaactttga tggtcgagtt
     2881 cttgttgaat aataccggag caaggtattc tatgataccg aactgagtaa caggtatttc
     2941 tccttcatac aatttctttt tgccgtccgt cagcgtcacc attgcctgtc ccggtacgtt
     3001 ataagcaatg ccttccatct ctttcttctt tttcccgtcc tcttgcggaa tcttcaccgt
     3061 tttcaggtct ttcagactga tgtagaatgg agtgcctgcc aaatcgttgt tggcaactat
     3121 acccagcttc tttgaaaagc ggaaagctac ctcattgtcg aattccttat ccggagtgag
     3181 gcggacagta aatgtctttt cttctttatt gcggactccc gaaaacatct cggtcatggc
     3241 ttcttcctga agattcaagt tgtcgagcat gattttgagc tgtgcgccgt ccgaaggcat
     3301 attatctgct tgtccgcgca ataatgcgtt tttactttcg cggatattat agatttcctt
     3361 tgctaccagt tcggccatct tggcggttga acttgccatc agaatttctt cggtgagaaa
     3421 gtcgcgggga ttggcttttc gttggggagc aacggcattg tttgctgcat tctttgcatt
     3481 gttactactg taggggacgt tgatcgattt gataagaccc tcttcagtca gttccataag
     3541 aggagctacg gttttatctt tcagtttgac gaaataagta gcttcgctgt ttggtacacc
     3601 tacaggtttc actttgacgc tgttcaattc ccagtattct tcgggttcgg cagagacgtt
     3661 ggtcagtctc aggtagcggt cggcgtattt gctgaattca cccggcttat agttgacttt
     3721 gtttgctttt atttctattt ctatctgggt tttggggagg gcgtacacta ctccgtagtc
     3781 ttttcctcgc gtcactcctg tcagcacttc ggtctgcgca taggcggaag ttgccattag
     3841 tagtcctgtt gctatgatta actttttcat attcggttct ttttagctga ttttgaaaaa
     3901 caaagttaat gaagttattg aataaaccgt aagttcttaa cttttattcg cttacaagtc
     3961 gccatgccgt cggcagacag gtcacgatat cacttgcgat taatccgatc atgccctgct
     4021 ttttctgggc gatgtctccg gccaatccgt gaatgtaagt accgatcttt gcggcatctt
     4081 cggcaggata gccttgcgca agaagtgcca ggattactcc tgtcagtacg tctccgctgc
     4141 ctcctgttgc cataccggga ttaccggttt ggttgaagta acatttgcct tcgggggtga
     4201 taatggcgga ataagctccc ttcagaatga tatgtacttt ggcagtgtgc gccagttcgc
     4261 aggctttcat gagtcgttcg tatgagtcct gacatttgcc gaccaggcgt tccagctctt
     4321 tcgggtgagg ggtgaggatg gaacctttcg gcagatgggt gagcgtatgc cggtgattgg
     4381 ccagaatatt gagtgcgtcg gcatccagta ctgtcggagt ctgacaatgt tccagttgtt
     4441 ctatcaaggc ggcttccgtt tcctcgctgc gaccgagtcc cggaccgatg ccgacagctt
     4501 gataatcatc cgtatcggta ggtacggcaa agcaagtttc gctgacatct gtttctacta
     4561 tggcttcggg ggcagacgtt tgcagaatat cgttgttgca taacggcgcg tgtacggtca
     4621 gcagacctac tcccgagcgc agacaggcac gcgcggccag taccgatgca cctgccattc
     4681 cttttgagcc ggctatcagc agggcatgtc cgaagtttcc tttatgggcg aattgttggc
     4741 gtggtttgat cagtgaacgg atttcttcga tttccagcat ttcgtagttt gtttcagtct
     4801 cttcgattcc ttcttcgctc agctggatgt ccaataactc ccattcgcca acaaattctg
     4861 tattttcggc aaagaggaag gccagtttag gaagttgcag gctgaaagtg acgtccgcac
     4921 ggataatatt gctttttaca ttgaatgtat tttcttctcc catcagcccg gaagggatgt
     4981 cgatggagac taccatggcg ggagaggcat tgatatattt cacaacggca gcgaatcctc
     5041 cgctcaatgg tttgttgagt ccggaaccga ataatccgtc gatcacgaga tgctccgatg
     5101 tcagtgtggg cggtacgaac tgggtgctga tttcatggaa agttacttct tccatcatct
     5161 ctaccagttc tttgttggtc tggcagtcgg gcgaaagttc gcctttcgtg ttgaagagat
     5221 atacttcgat cttgtatcct ttttccgcca tcatgcgggc gatggcgagg gcgtctccgc
     5281 cattattgcc cggtccggca aagatggtga caggtgtttc cggattccat ctgttagtga
     5341 tggctttagt cagcgcctgt gcggcacgtt ccattaaatc aatggatgca atcggttcat
     5401 gttcaatggt ataggcatct aacttcttaa tgctgctgct tggaaatatt ttcattgcga
     5461 tattctttta gttttcgacg cacaaactta cacaaaaact ctgaattaat cctttattcc
     5521 ggttggtttt cggctttttg ggaaggaact tcaggtatta atagttgatg tgtcagttat
     5581 taatagttga gaagtcagat attaatgatt gttatggtag atatcaatgc ttgttatgat
     5641 ggctttcaat gcttgtaacg cagtataaca agcattgtta tctcatttac ttttactctc
     5701 tccggagaac attcatggct gtttgttaac cttcccatgc gtgtttctac tactgtatat
     5761 tcctctggtt cacctctttc acccgcaatc gccttattta tcaaaggttc aggaaaaggg
     5821 tggaagaggt gattgtgata aatatgctat gggcatattc ttgattagct aatagcttat
     5881 tgttttttgc taaatctaat ggggagtttg ctcatataat aaatactcta ttcactctgc
     5941 taaagaagaa aatcagtgta gctctcattc tgctatttga atcagatatg cattttccag
     6001 tgcaaggtaa tcttgtttgt actgtgcggt taaatctctg acaaaacagt actgaattaa
     6061 cggatgagca ttcattcttg tattgaggag tggtagaaag ttcttggtaa tatagaaagt
     6121 atcaataact ttgccattat cttctttgat tgttatacgg taatactcac tcaatttgta
     6181 ttcacctttg atgggaatgg cattttcttc atccagcact atatgttctt tttcaaagtt
     6241 gcctgttttc atgttattat ctgaataata caaatctact gttcctttgc tgtcttccgc
     6301 attcataaaa gtaaatacat atttattaat cggatatgaa ttgcccactt tgttcattaa
     6361 ctcagtgtgt tcttcagatg taagctcgtc tcccttcaca atgacttttg ctgtaaacgc
     6421 cttatgagta agagtacgat attttacaac gacagacagt atatacatat tattcgaact
     6481 gtcttctatc ttgatggatg cgcgtcctat ttcctttgcc ttcaatgtta aacttccgtt
     6541 gtggtagttt acttgtacca ctttctcatt ctcattggtc actttgtaag ttccgtctcc
     6601 acccttgatg aagagtggtg tcgtttcttt gctgaacgga gtcagtgtgt aagaacggct
     6661 ctcgttgtcg aacttaattt gaggatcttc atattccaga gtgattggag aaaagttgtc
     6721 atcattgtca ttacagctca cgaggcaaat aatacaaagg aataacgaaa gtattcctgt
     6781 tagttttttg gtagtcatgc taattaaagt tttaaatgtg tgatattagt ttagttctcg
     6841 tctgcaaact tatgaaaaag aattgaactg tttctttatt tgtgctattt tttagcagag
     6901 atcggcataa atgattagaa tgtaactaat aatagcagct aatgctttga ttatttgctt
     6961 atttcgtaaa aaatgatatc tttgtagtgc agtaatgtgc tttacgttat tctcctgtgc
     7021 tcacaatgtt tagattataa atataaattg tttaatcttc taaagtttgc atgatggaaa
     7081 agaaaagaat tggctcaaat gccgggaaag tatggcgcat cttaaatgaa aagggcgaac
     7141 tgtccatgtt cactttgtgc catgagttag gtttgacgtt cgaggatgta gcgattgcta
     7201 tcggctggtt ggcaagggaa aacaaaatcc tgcttagaaa aaaagaagga atgctctatg
     7261 ccagtattga gaatgttgaa tttacctttg gataaatggg gactgaccca catttaagga
     7321 gaatatccac ttgattattt acactgttga aaacataata aggtgggtaa ctgagacttt
     7381 ttgcacgcca tcctgtattt ttctattcca taagaatctt cttttttgag gcatttaatc
     7441 tactttttag tacctttgca ccccataaac tactaaacac ataattcatg agttcattga
     7501 aagggcaccc gaaaggcctt tacctaattt tcgcaacgag cacggcagaa cgtttcagtt
     7561 actacggtat gcgtgctatc tttatcctct ttctgacgca ggcattgctt tttgataaag
     7621 aagcggcggc ctctatctac ggtagctaca ccggactggt ctatctgact ccgttgatcg
     7681 gcggatacat tgccgataaa tattggggta tccgtcgttc ggtattttgg ggagcggtga
     7741 tgatggcagt cggtcagttc ctgatgttta tgagtgcctc ttcactgaac aatacagacc
     7801 ttgcccactg gctgatgtat ggcggactcg gattcatgat tttaggtaac ggttgcttta
     7861 agcctaccgt ttcttcgctc gtcgggcaat tatatgaacc cggggacaaa cggttggatg
     7921 ctgcatacac cattttctat atgggtgtta atgtaggttc tttcgctgct cctttgattt
     7981 gcggtttctt gggagacaca gggaatccgc aggactttaa atggggattc ctcgcatccg
     8041 gaattatgac gctgttcact gttgtcctct ttgaaactca gaagaataaa taccttttct
     8101 ctccttccgg tgaaccgatt ggtatcgtcc ccgacgccag acgtgaaaaa aaggaggata
     8161 aagccgaaca tatttcacat ccgaagatgg acaaacgtac caaagtacgt aatatcatca
     8221 tcattactgc ccttacagtt gccttaatag ccttttttag ctatgccttt agcgatgact
     8281 ggattagtgt gggtatcttt acggcttgta ttgtctttcc agtgctcatt ctgctggatg
     8341 gttcattgac caaagtagaa cgtagccgta ttttcgtaat ctatatcgta gctttcttcg
     8401 tcattttctt ctgggcagct tacgagcagg caggagcttc tctgacatta ttcgcttctg
     8461 aacagactga ccgcagcatt ttcggctggg agatgccggc ttcgtggttc cagtcattca
     8521 atccgctttt tgtagtgatc cttgcctata ttatgcccgg tatatggagc tttctgaata
     8581 agcgaaacat ggaaccggct tcccctacca aacaggcaat cggtctgtta ctgctttctc
     8641 ttggttatct cttcatctgt tttggagtga aagatgctat tccgggagta aaggtgagca
     8701 tgatctggct gacaggactt tattttattc atacaatggg agaaatcgct ctgtcaccta
     8761 tcgggctttc tatggttaat aagttgagtc cgttacgttt cgcctccttg atgatgggga
     8821 tctggtatct ttctaccgcc accgcaaata aatttgcagg tatgctgagc ggcctctatc
     8881 ccgaagacgg aaaagtgaaa tcaatccttg gttatcagat cgctaccatg tacgacttct
     8941 tcatgctgtt cgtcattatg tccggtgttg cctcactgat tctgttcctt ctctcgaaga
     9001 aattacagaa gatgatgcac ggggtagaat aaaaaattgt atttttgcga caactttttt
     9061 aaaatgaccg gttatggata ccatacagat aaaagacaag caatttactg tttccattaa
     9121 ggaacaggat attcaaaaag aagtgattcg cgtagcgaac gaaatcaatc gtgatttggc
     9181 aggtaagaat ccgctcttcc tcagtgtgtt gaacggctcg ttcatgttta ccgccgactt
     9241 gctgaagcat attacgattc cgtgcgaaat ttcattcgtg aagttggcat cttatcaggg
     9301 ggtgacttcc accggagtaa ttaaagaagt gatcgggctg aatgaagaca ttgccggacg
     9361 tacggtagtg atcgtagaag atattgtaga taccggactg acgatgcagc gtctgctgga
     9421 tacactgggc acacgtaacc ccgaagcgat tcatatcgcc tctttgctgg tgaaaccgga
     9481 aaagctgaag gtcaatctga acatagaata cgtagcgatg gaaataccga atgattttat
     9541 cgttggctac ggattggatt atgatggttt cggacgcaat tatcccgata tttatactgt
     9601 agtagattaa attcaaatac aaattaattt ttaggttaaa aagatgttga acattgtaat
     9661 tttcggtgct ccgggttcag gaaaaggaac gcagagcgaa cgtattgtag aaaagtatgg
     9721 aatcaaccac atctcgacag gagatgtatt gcgtgcagaa atcaagaacg gcacggaact
     9781 gggcaaaact gctaaaggtt acatcgacca ggggcagttg attccggatg aattgatgat
     9841 tgatattctg gcaagcgtat tcgatagctt caaagacagc aaaggtgtaa ttttcgacgg
     9901 tttcccaaga acaattgcac aggcggaagc attaaagaag atgttggcgg aaagaggaca
     9961 ggatgtttct gtaatgttgg atctcgaagt tccggaagat gaactgatgg tacgtctgat
    10021 caaacgtggc aaagactccg gtcgtgccga cgacaacgaa gaaacaatca aaaaacgtct
    10081 gcatgtatat cattcacaga catctccgct gatcgactgg tacaagaacg aaaagaaata
    10141 ccagcacatc aacggtttgg gtactatgga tggtatcttc gctgatatct gcgaagcggt
    10201 agacaaatta taataaataa aaaatatggc tgaatcgaat tttgttgatt acgtaaagat
    10261 atactgtcgc tcaggcaagg gcggaagagg ctctacgcac atgaggcgcg agaaatattg
    10321 tcctaacgga ggtcccgatg ggggcgatgg tggaagagga ggccatatta tcttgcgcgg
    10381 taaccgtaat tactggacat tgcttcactt gaagtatgac cgtcatgcga tggcaggtca
    10441 tggcgaatcg ggcagcaaga accgtagttt cggaaaagac ggtgcggata aagtgatcga
    10501 agtaccctgc ggaacggtag tgtataacgc cgaaaccgga gaataccttt gcgatgtgac
    10561 ggacgacgga caggaagtga tcttgctgaa aggcggtcgt ggcggtcagg gcaacagtca
    10621 tttcaagacg gctacccgtc aggctccgcg ctttgcgcag ccgggcgaac cgatgcagga
    10681 aatgacggtg atcatggagc tgaaactgtt ggcagatgta ggactggtag gtttcccgaa
    10741 tgcgggaaag tctacgttac tttctgccat ttcggctgcg aaaccgaaga ttgctgatta
    10801 cccgtttacg acactcgaac cgaatttggg aattgtttcc tatcgcgatg gaaagtcatt
    10861 cgtgatggcg gacataccgg gcatcatcga gggagccagt cagggaaaag gattgggact
    10921 gcggtttctg cgtcatatcg agcgtaactc gttgctgttg ttcatggttc cggcggatag
    10981 cgatgatatc cgcaaggagt atgaagtatt gctgaatgag ctgcgtacgt tcaatcccga
    11041 aatgctggac aaacaacgtg tgctggctat cacgaagagc gatatgcttg atcaggagct
    11101 gatggacgag attgaaccga cattgcccga gggcgttccg catatattca tttcttctgt
    11161 ttccggtttg ggaatctcag tgttgaaaga cattttgtgg gaggaactga acaaggaaag
    11221 taataagata gaagacattg ttcaccgtcc gaaagacgtg acccgtctgc agcaggaact
    11281 caaagatatg ggcgaggatg aagaactcga ctatgaatat gaggaagacg ctgacgacga
    11341 cgatgatgat ctcgactatg aatacgaaga agaggattgg gaggaaaaat gatttcaatc
    11401 acaagagata aaagaatgtt ggggtatgag tcgttaagct catactccaa catttctcat
    11461 tttgtaacta cccggcaggg aggatgcagc gagggaaatt atgcgtcatt caactgtacg
    11521 ccttacagtg gcgacgaggc ggaaaaggtc cggcggaatc agacgcttct gatggaagga
    11581 atgtcgcaga cacccgaaga actggtgatt cctgtgcaga ctcatgagac gaattgcctg
    11641 ctgatcggcg atgcttattt atcggcttcg tctcaacaac gacaggagat gttacatgga
    11701 gtagatgcat tgattacccg tgagccggga tattgtcttt gtatttctac tgcagattgt
    11761 gtgcctgtgc tggtatatga taagaaacat ggtgccatag ccgccattca tgccggatgg
    11821 agagggacgg tagcgtacat cgtgcgtgat actttgttga ggatggaaaa ggagtttggc
    11881 acaagtggag aagatgtggt ggcctgtatc ggtccgagta tctcattggc ttcttttgaa
    11941 gtgggtgagg aagtgtacga agcatttcag aagaatggtt ttgatatgcc ccgtatttct
    12001 atcaggaaag aggaaaccgg aaaacatcat atcgacttgt gggaagcgaa ccggatgcaa
    12061 atccttgctt tcggtgtgcc atccggacag gtggagcttg cccggatatg tacgtatatt
    12121 catcacgacg agtttttctc ggcaaggcgt ttgggcatta agtctggacg gattctgtcg
    12181 gggatcatga ttcataaata atagttttga acatagattg acataaataa gcgcataggt
    12241 tggaatagac ttgaacgtaa gttgatataa acttgaataa aagtatgttt gaaataaaag
    12301 tatctcagga aataaagaac gcctgccctg tttttgccgg agcagccgta tatgcagcag
    12361 tgaagaatac tgcttactgc gatggacttt ggaaagaaat aaatactttc acagaagact
    12421 tgactaccac cacccaaatg gcagacatta agttgcaatc tgtgattgct gctacccgtg
    12481 aggcttataa gcgttgcgga aaagatc
//
