LOCUS       c00045_gnlPro..        25251 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBPNCJJM_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 18:59:38
            Original ID  :: gnl|Prokka|CBPNCJJM_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 35700
            Orig. end    :: 60951
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25251
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[45700:50951]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15251
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..25251
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25251
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1430..1675)
                     /locus_tag="ctg45_35"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
     CDS             complement(1685..2419)
                     /locus_tag="ctg45_36"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             complement(2451..4913)
                     /locus_tag="ctg45_37"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             complement(5085..6644)
                     /locus_tag="ctg45_38"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             6883..7713
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_39"
                     /sec_met_domain="GHMP_kinases_C (E-value: 4.3e-10,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 5.8e-10,
                     bitscore: 32.2, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFILKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             complement(7746..8108)
                     /locus_tag="ctg45_40"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(8119..8418)
                     /locus_tag="ctg45_41"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             complement(8742..9776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_42"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.9e-51, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_43"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.9e-62, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(10596..11162)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_44"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.4e-69, bitscore:
                     225.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMPEEYGML
                     VFVLAPGAFIALGYLIALINSFKKA"
     CDS             complement(11195..11911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_45"
                     /sec_met_domain="FMN_bind (E-value: 2.5e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAN"
     CDS             complement(11938..12930)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_46"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.3e-119,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(12936..14273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_47"
                     /sec_met_domain="Fer4_10 (E-value: 1.1e-08, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 6.3e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.9e-50, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.1e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(14298..15251)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_48"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.6e-08, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.4e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 9.4e-08, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.3e-10, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKPAAVSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             complement(16057..16197)
                     /locus_tag="ctg45_49"
                     /transl_table=11
                     /translation="MKKKTVCCSDLGAYINELLKRAKLKNEYVCETLGMGHDVLNGIKK
                     G"
     CDS             16365..16991
                     /locus_tag="ctg45_50"
                     /transl_table=11
                     /translation="MMSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQM
                     ITCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFTRRSCKDFVSPSHLVIVDVDGL
                     HSYQEAVEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCHYSPTINDAQNITDNMSWAM
                     RYVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTK"
     CDS             17030..18871
                     /locus_tag="ctg45_51"
                     /transl_table=11
                     /translation="MTDIESLCRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPTHTGAHNKVGNDNISDDREGEEELLPGSEPQHQLPTFPENDWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVTIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKTHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGREMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPTDNRKDDIITRWDVSISQ
                     EDFHAVLSLAEPLYCHATHILSFLPSTEISHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKHGKLISMDGKGLYARACVYE"
     CDS             complement(19053..19271)
                     /locus_tag="ctg45_52"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             19491..19979
                     /locus_tag="ctg45_53"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             20278..20706
                     /locus_tag="ctg45_54"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRGRALEKVGAHCRNHNTHSIGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALIVGHRDLNPMKGCPCFDAVKEYSQVISYQK"
     CDS             complement(20992..21429)
                     /locus_tag="ctg45_55"
                     /transl_table=11
                     /translation="MEFDKEFLDKLFEQAMENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGKLDEVIYEEVVSYEKDTDDFQKGVNVQDVARKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(21435..22433)
                     /locus_tag="ctg45_56"
                     /transl_table=11
                     /translation="MNAYLTYGIIFVILLALELCYFKVADHFNIIDKPNERSSHSTIVL
                     RGGGIIFLIGVWIWSAFFGFQYPWFLLGLTLVASISFVDDIHSLPDSVRLVAQFAAAAM
                     AFYQLGILHWSMWWVILLALIVYVGATNVINFMDGINGITAGYSLAVLIPLALVNMDDI
                     FVEQSLIISTILASLVFCIFNFRPKGKAKCFAGDVGSIGIAFIILFLLGNVMIETTDIT
                     WLIFLLVYGVDGCLTIVHRIMLHENLGEAHRKHAYQIMANELKVGHVKVALLYTVMQLV
                     ISLGFIYLCPDTVIAHWLYLVGVSAVLAVAYILFMKKNYHLHEEYLISLKQ"
     CDS             complement(22441..23430)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_HSD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_57"
                     /sec_met_domain="Beta_HSD (E-value: 2.1e-09, bitscore:
                     29.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 1.3e-18, bitscore:
                     60.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILITGVHGFVGSNLVKALSPENTIYGLDIVAPEKEGIVKTFLW
                     DDLGGIDLPQIDAVIHLAGKAHDTRNKSAADVYFKVNTGLTQRIFDWFLSNESAKKFIF
                     FSTVKSASDKVEGKCLTEECVPTPVGPYGESKIKAEDYIIGHFAPEALKRPYHNFDDSD
                     SLVKGKNVYIIRPCMIHGPGNKGNLNLLYGVVSKGIPWPLGAFENRRSFTSIGNLCVVI
                     DGFLTKNVPSGIYHMGDDEALSTNELIQVICEALGKKAHIWCIPKGLMNGVAKVGGWFH
                     LPLNPLRMQKLTENYVVSNAKIKAALGITRMPVRAKDGLMDTIRSFKQ"
     CDS             complement(23433..24530)
                     /locus_tag="ctg45_58"
                     /transl_table=11
                     /translation="MRTVFIGAHEEPNGVNSYTYNLALELKKRGFESFVMSFGSCNKVT
                     DYKGVKIKQYRTWGNTMTSIPVLYLKSLPYLIKHRKEIDMVMYQTVTFSVIPSLIVRLF
                     GMKSSAIIHSLAEDSPKHGKMMKKLLMASMRLALAFTKNVVTVSCTKAKEVYNRYHKSC
                     KVLPCGVFLPINKELNTDILEKNEIQVGKFFLTIGRIDPIKNYEVLIDAFKRHNHVNYQ
                     LVIGGDINNAYGRTIVERAKGCKNIIFPGIVYGDAKIALLKNCMAYCLVSSSEGLPIAL
                     LEGMSYGKIPVVTRIPSIQEVLEKYEIGLWSTVKNVEEVIANMIAIEKDFNTLKVQGKT
                     ARQIVEDNYTWPQICDRYIELVKEF"
ORIGIN
        1 cagtaccgaa acaataatgg caatcgaata caacacaaac gtgctccaac gactattgac
       61 ataatctccc atcacctttc gggaagacgt cagtcccacc tgcaaaaata ccgtgaaagg
      121 taattgaata ctaagtatca tctgcgaaat aatcaatcct ttgaaaggat ctccaataaa
      181 gaaaatcagc aataaggcaa ttcccagaga taaaaggact cctacctgcg agtggctgtc
      241 tttgatatga tacgattcac cgaaaatacc cgcaaagatg gaacctgccg ccattccgct
      301 cgtaatggtg gatgaaatac ccgccatcag caatgccagt gcaaatacga tggcagcatt
      361 acttcccaac aaaggttcga gcaatgactt agcctgttgc agttcctcta cctgaatacc
      421 gcttttaaag aaagtagcgg cagccagaag aatcatggca ctgttaatcg cccagccgac
      481 aatcattgag aaaagagtat caaacaactc atatttcaag accttcttaa tagaagcatc
      541 atctttctta ttatattcgt gactctgtat cacctccgaa tgaagaaaca gattatgagg
      601 catcactacc gctcccaaca cactcatgat aatcagcata cttcctttcg gaaaagaagg
      661 agtcacccac cctgctgtcg cagccggcca gtctatttcc accagaaaca gttcatagat
      721 aaacgaaagc ccgataacag agacaaatgc aatgatggaa cgctctatct ttttatacga
      781 attagtgaaa agcatgatag agacaaaaag cgtagtcaac acagctcccc atataatagg
      841 aatatcaaag agcatttcca acgcaatggc acctcccaga atttccgcta aagaagtaga
      901 aatcgacgcc agtaccgccg taccaagaat aggtcgcgac acccatttgg gagtgtattt
      961 agtggccgcc tccgaaaggc aaagtccggt aacaatcccc aggtgggcaa cgttgtgctg
     1021 aagcacaatc agcataatag tggacaatgt aaccacccaa agtaaggaat agccaaattc
     1081 ggaaccggcg gcgaagttag aagcccagtt tcccggatca ataaatccta ccgtaactag
     1141 aagccccgga ccaatatatt taaaaacatc cagtccaccc agatagcgtt tatgatcttt
     1201 gcgttttaag tcttgaaaaa tattcttcat ttttgcataa tagttttaac cttacaaata
     1261 tacttataaa taacgagtga aggtcaattt tagttcaaaa taccgacaag taagtaaaca
     1321 acacccggat ccccccccct atggattccc acaaaaaaaa gaccctcgac aaaataaatt
     1381 gccgaaggtc ttgaaaaata tcaaatttta caaaaataaa agaagtcgat taatatccca
     1441 tctcatgtaa tgcacgacac aattggtcag gacatgaagt cggtctgcca ccacaatgca
     1501 ctccttcaag ttttgcgata acatccgcta ccttcattcc tctcacaagg cgggaaatac
     1561 cttgaaggtt accattacat cctccccaaa aagcaacttc tttcaccact ccatcttcca
     1621 cattcagttc gatgttggtg ctacaagttc cctgggttct atacacatat tccataacct
     1681 tgtcttattc tccctcttcc ggctgcatat tggtataaac agtctgcacg tcgtcaaatt
     1741 cttctaaacg ttcgatcatc ttatccaatg tttcgcgctg ttccggagtc acctctttca
     1801 tgtcgttcgg gatataagtg aagtctccac cgacatcttc aaagccacac tcctccaggt
     1861 gtttctgaat agcggcatag ctcttgggat taccatagat agtgattgtt ccttcttcat
     1921 catcctcttc gtattcatcc tccacatcat aatcgatcag atccagaatc agttcttcca
     1981 tatccaatcc gtctttcttc ttgaaagtga atacacattt gtggtcgaac aggaacgcga
     2041 gagatcccat tgtaccgaga ttaccgccaa acttattaaa taccgaacga acgtcagcca
     2101 ccgtacgggt tgtgttatct gtcagcgtat ccacaaatac agcaataccg tgaggaccgt
     2161 atccttcgta agtcatgctc ttgtagtcgc tctggtcttt acccattgcg tttttgatag
     2221 cacgttcaat attatccttc ggcatatttt cacgcttaca agtagcgatc accgaacgca
     2281 aagtcgggtt attttcaggt tccggaccgc ctgcctttac agctatcgcg atttgtttac
     2341 ccagtcttgt aaatgtttta gccatgtggc cccatctttt cagtttagcg gcctttctat
     2401 attcaaatgc tcttcccatt ggtttatatt tttagattga aattttaagt ttatctaagt
     2461 ttggcaccca gcttatcttc caagttcttc accagtttcg acatgatctt atcaatcatc
     2521 ttatcattca aagtctggct ctcatcctga agcaggaagc tcaccgcata cgacttcttg
     2581 cctgcttcca gattcttacc ttcgtacacg tcgaagagtt ccacttcttt caacagcttc
     2641 ttctctgttt cgtaagcaat cttttcgatt tcggcaaact gcacattctt gtcaagcaac
     2701 aatgccaggt cacgtttcac agcagggaac ttggagattt ccttgtagct gatcttcaca
     2761 gaacggatag ctttcatcag ttccttccag ttcaagtcgg caaaatacac ttcattgtcg
     2821 atatcaaatg ctttcaacag cttcttagtc acgataccga aggaagcaag acgcttacca
     2881 cccttcgtat tgatagaaag tgcggcagca aaaatatcgt ccgtcagatt accgacaacc
     2941 agattgtgca aatccagtcc cagacgcttc aatatatttt ctacataagc cttcaattca
     3001 tataccgaac tgttctcatc tgcatgtgcc catgaattgg aaaccttctt accggttacc
     3061 cacaagccca agtgataatc ttccgagtaa ggagccaata ccttctcttc attcttcttg
     3121 tcagcatcga aatgatagca attaccgaat tcgaagaact tcaaatcagc attcttacga
     3181 tttgcattat gagcaatact ttccagtcca ccgaacagca aagtctgacg catagcgttc
     3241 aaatccgcac tcaacggatt caataacatc actagatggt tggacggata agtctccata
     3301 ccatcataat aagcagcacg cgtcaatgag ttgttcagga tctcattaaa tccgcagccc
     3361 accaattgct ctgcaatcag gttctgcaat ttattcgatt tatcatgttc acctttggta
     3421 gtcaggctgg agttcagtgt agtcgggatt tcaacattgt tatatccgta gatacgaaga
     3481 atatcttcaa tcacgtcaca atcacgctgc acgtctacac gataaggagg aacagctaat
     3541 gtcagccctt ccgccgtttc attagtgatc ttcatttcca ggctggtcac aatgctcttg
     3601 atcgtctcta ccggaattac ttttcctacc aaagaatgta ctttctcata agccagatca
     3661 actataaaat cgggtgcagg agtagtgaac acgtctttta tttcagaaga aatcgtaccg
     3721 ccagccagtt ctttaaccat caaagcagcc agtttcaagc aatatatcac actgttcgga
     3781 tcgataccgc gttcgaaacg gaaagaagca tccgtattca agccatgacg gcgggctgtc
     3841 ttacgcaccc atgtaggatg gaaataagca ctttcaatga atacatctgt cgtagcttcc
     3901 gtagaaccgg agtccagtcc gccgaataca ccggcaatac acatggcctc ttccttgtta
     3961 caaatcatca ggtcgcgttc gttcaattta cgttccacct catccagcgt aacgaacgga
     4021 gttccttccg gcattgtctt tacaattact tcattgcctt ttatctttcc ggcatcgaag
     4081 cagtgcaacg gctgaccgaa agcatgaacg atataattag taatatccac tacattatta
     4141 ataggacgca ccccgatcag acgcaatttg ttttgcagcc attccgggct ttccttcaca
     4201 gtgacacctt tcaccgtaac accggcataa tgcggacaag cttcgctgtt ttccaccttc
     4261 acttcaatat tcaagtcatg gttttccact ttaaagccgt ctaccgacgg acgttgcaaa
     4321 gtagcctgtt tgccgttctg aatcagataa gcgtacaagt cacgagccac cccatagtga
     4381 gagcaagcat ccgcacggtt aggcgtaatg tccacttcaa gcacatagtc gctcttgata
     4441 ttataataat ccttggcaag cgtacccgga acagcatttt ccggcaatac gataatacct
     4501 gcatgatccg taccgatacc gatttcgtct tcagcacaaa tcataccagt agattccacc
     4561 ccacggattt ttgatttctt gatggtaaaa cattcgtcac cgtcataaag tttcgtacct
     4621 aaagtagcta ccaccacttt ctgtccggca gccacattcg gggcaccaca aacaatctgt
     4681 accggttcac cgtctcccag attaacagta gtaatatgca aatggtcaga attaggatgt
     4741 tccgtgcagg tcagcacttc accgatcacc agtccttcca aaccaccttt aatggtttgc
     4801 acttcttcta caccacctgt ttccaagccg atagaagtca acgcagcagc cgtttcatcg
     4861 ggcgtcaggt cgaagttgac atactctttc agccagttat aagagatatt catatattta
     4921 attttttatt gtttctcaaa aagatttgca aagttaataa gatttttcgg ttgaccgaga
     4981 aggttagata aaaaagttta tagttgatag ttaccatgcg gaataacata cagatagaag
     5041 aaatgttgcg cagagcattt tcactatcag ttatcaacta ttaactaaaa tggtaacggt
     5101 ccatctcccg gtgctccgaa tggattctcc gtctgcggtg caaaatcagg tgcgggagga
     5161 ggtatggaac cagcattacc tgtattcatt ttcgatccta acatagctcc tgcaggctcg
     5221 cccggcatcg ggatcaccat atcgtcctcc ggattagaga aacgggtaaa ctcaccctta
     5281 aagcggagca acacctcgcc taccgcaccg ttacgatgct tggcgattac aatttccgcc
     5341 ataccgcgca agtcattacc acgatcatcc tgaaatatct tatagtattc cggacggtgg
     5401 ataaagcaca ccatatcggc atcctgctcg atggctcccg attcacgaag gtcactcaac
     5461 tgcggtcgtt taccgtcaat accttcacga ctttccacac cacgattcaa ctgtgacagt
     5521 gcgataatcg gaatactcaa ctctttcgcc aatcctttca acgaacggga aatggtacta
     5581 acctcttcct gacggctacc aaacgccatc ccactcgcat tcatcaactg aaggtagtca
     5641 atgatgatga ttcgcacccc atgttcgcgt accaaacgac gcgctttggt tcgaagttca
     5701 aacacagaca gagacggcgt atcatccacg taaagcggtg catccatcag attcttcagt
     5761 ttatagtcca gttgttgcca ttcataattt gccaactgcc cgcttttgat tttctcgctc
     5821 ggaatctcgc agacattcgc aatcaaacgg ttcaccaact gaacgttact catttcaaga
     5881 gagaacaacg ccaccgggtt ccggtaatcc accgcaatat tcttagccat tgaaagaacg
     5941 aaagcagtct tacccatagc aggacgggca gctataataa taaggtcgga attctgccaa
     6001 cccgaagtca tcttatcaag tttcgtgaaa ccactctcca gaccactcaa accatcggtt
     6061 cgagccgcag ctttctgaat tagtttatag gcttcgtcaa tcaccggatt gatctgcgta
     6121 taatcttttt tcatattctg ctgtgagatc tcgaaaagct taccttccgc ttcctgcatc
     6181 aagtcgtcca catccaacgt ttcatcaaac gctttactct gaatattact cgtaaacgtt
     6241 atcagctcac gcgccagcga tttctgtgca ataatacggg catggtattc aatatgtgcg
     6301 gatgaagcca ccttactact caattgagta atatagaagg gacctcccac ctcttccaag
     6361 tctccgcgtt tactaagttg ttcctttaca gtcagaatat ccaccggttt ctggttcacc
     6421 gcaagatcga cgatagcaga ataaatcaac tgatgccggc gttcgtaaaa tgattcggga
     6481 cgaagaattt cactcaccaa tgaataagcg tccttttcaa tcattaaagc tcccaaaact
     6541 gcttcttcca gttcaggcgc ctgcggctga atacgaccat aatcatttac cggttgtatt
     6601 ttagtagact ttgaattgcg ggtatttctt ttctgttcgg ccatcgagat atttactatt
     6661 ttacgattta ctatttatta ttttacgact ggacagactc tattatcaca tttatcacgg
     6721 aattcttcca gtcgagacga caaagataga atataatcac gaagaatgaa taaggaaaaa
     6781 tgaagatttt agtaactttg ctcccgattc acattatcca gctatgatta attgtaatgt
     6841 gaagcactgt aaatagtaaa tagtaaaata gtaaatagaa atatgattgc ttttcccaat
     6901 atcaaaataa acctgggact ttccatcacg gaaaaacgcc cggacggata ccacaatctg
     6961 gaaacagttt tctatccggt ggctctggaa gacgcactgg aaatccgtac ctcccctaac
     7021 gctgaccgaa aattcactct ccaccaacat ggaatggaaa tagccggtaa ccctgaagac
     7081 aatctggtag taaaagccta tttattgatg gataaggaat ttcatctccc tcctatcgaa
     7141 atccacttat acaagcacat cccttcagga gccggactgg gaggaggatc atcggatgcc
     7201 gctttcatac taaagttgct caacgatcat tatcagctgg gagtatccga agaacaattg
     7261 gaagtatacg ctgccacttt gggagcagac tgcgctttct ttatcaaaaa cagaccgata
     7321 tttgccgagg gaattggaaa catcttctcc ccggtcgaac tttcattaaa cggctaccaa
     7381 atcatgatta taaaaccgaa tgtttttgtt tccacccggg aagccttttc aaacattcat
     7441 ccccatcgtc cgaaatatcc ggttagggag gcaatccagc gtcctgtaca agaatggaag
     7501 gatacgttaa tcaatgattt cgaagcaagt gtattcccgc aacatcccgt cattggagaa
     7561 atcaaagaag aactctatca tcaaggagca atctacgcat ccatgagcgg ctccggctca
     7621 tccgtattcg ggctgtttgc tcccggattc gtcttaccgg aaattgattg gggaactgat
     7681 gtattctgct tcaaaggtac attaaacaaa taaatctcac taacaattat gttttgacta
     7741 ttttttcaaa atcccaacat ggcagcgggg tgtatattga gtacccggca aagcaagcga
     7801 gctattttta aagtaggttc cgagcgaccc gaaatataat cattcacgcg tgaagggcta
     7861 acccctattt cactggcaag ctgtttttgt gtcatcccct tttcttcaag ggacaattct
     7921 atcaattctg ctacggttgg tttttctata ggaaaatgtt ccttctcata cgcaatcact
     7981 atatcagaca taacagaaag ctccaccatg ctcttgtcat ttgcaggagt gctgtcgtcc
     8041 accaaaggca gaagttcttc gactcttgcc aatgcaaatt cgtattgttc tttcgttatt
     8101 ttagtcatat ctattatatt atatagttga acaatctatt ttatcatact ctttatgagt
     8161 tcccacccaa cggacaaaaa tgtatcccac cgtaaattta acaaccacta ccagccgata
     8221 gttgttccct ctgatattaa aaacatagtg ttgattgccc acataatcag tcgatagaaa
     8281 atccgctttt atatcagaca aattccgcca ttctgctttt tccgctatat cataccaacg
     8341 ttctaaagca acacgtgaat cttcacaccc tttcgtctcg tagaaatctt tcaatttctt
     8401 atgtgatact actctcatat cttattcatt tgatacaaaa ttacaaaata attttggata
     8461 acaaaagaat tagtgctaaa tattttataa aacagaacat ccatgctggg cgtaccaaaa
     8521 aacggtacca cgactcacgt cgtagtaccg tcacaacaca aacacaaaat aaaacacgac
     8581 aaaactacta tgcaatcttt cctgtctatg ccggggaggc ataagtacta tctacgtata
     8641 ttcgcatact cataaacagc ttcaggtcga ttagcatcaa ttaaacaaat cgcatgcacg
     8701 atttgtttaa acttttatgt tatttaaaac aagtttctct tttattgaat ccctctttca
     8761 cggagtttca gctgccagtt ccatgcagag cgtaaagtat cttctaaagt ttctacggct
     8821 ttccaaccca gctctttatt agcaaaatcc gggttagccc aaactttttc aatgtcacct
     8881 gcacgacgtc cgacaatctg ataattcaat tttacaccag tggctttttc aaagccattt
     8941 attaattcca atacagaaac accacgtcct gtaccaatat taaatacttc tactttttct
     9001 ttttgtttct tttccaagat acgacggata gcaatcacgt gtgctttagc caagtcaacg
     9061 acattgataa agtcacggat acaagaaccg tccggtgtat cataatcgtc accaaacacg
     9121 ctaagtttct cacggatacc gatggctgtc tgggtcagat atggaatcag gttttgagga
     9181 accccgttag gcagttcacc aagcaatgca gtaggatgcg cgccaatcgg gttgaaatag
     9241 cgcaacatga tcgcattgat cggagcacct gaagctaccg tatcacgaat aatctcttca
     9301 ttgatctgtt tggtatttcc ataaggtgat tccgctttct tgatcggagc tttttccgtt
     9361 accggcagct cgtccggctg accgtatact gtacaagaag aagagaacac aataccttct
     9421 actccatgtt ttggcatcag ttcgagaagg ttaatcaaag aaaccaggtt attacggtag
     9481 taaagcaacg gtttttgtac cgactctcct actgctttgc tagctgcaaa gtgaatgatt
     9541 gccttaattc ctttatattt tgcaaatact gcatccagac cggcaaagtc caaacagtcc
     9601 agcttttcaa aaactgggcg aataccggaa actttctcta tattgtcaac aacgtcggca
     9661 cttgaatttg ataaattatc gatgatgatt acttcatatc cactgttttg tagttctaca
     9721 acagtatgag acccaatgta tcctgtcccg cctgttacta aaattctttc tttcatatac
     9781 tttataaaaa atggttagtt tctcggctta ttattgtttg agttacaaat gtatggaaat
     9841 aaaatgaaat tgcaataatc tgccacaaat ttatttgctg aaaagtaatt aaggtacgat
     9901 ttggtagcat ttaggtataa aaaagaattg gaaactctaa cctgtatgtc gccacacagc
     9961 agagcttcca atcccctatt taatcatcaa ctgtaaatcc ttacaccacg ccggagaatc
    10021 ccatgaatgc catagcaagc aaaccggcgg taatcaaagc aatcggagtt ccttgcattc
    10081 ctttcggaat tttcacaagg ctcatctgtt cgcgcaatcc ggcaaaaagc accagtgcca
    10141 gaccgaagcc gatagccgta gaaaacgcgt acacaacacc tgtcagcaga tcatagtctt
    10201 tctgaatcac caggatagcg acaccaagaa tacaacagtt cgttgtaatc agcggcaaga
    10261 acacacccaa agcctgatac agggccggag ataccttttt caggatgatt tccaccatct
    10321 gcaccaatcc ggcaatcacc aggatgaatg taatcgtctg caagtatccc agtccgaaaa
    10381 catccagtac aaacttctga atcaggaaag tgacgatggt agcgatggtc aacacgaaag
    10441 caaccgcagc gctcataccc atcgcagttt ccaccttctt ggatacgccc aggaacggac
    10501 agatacccag gaactgcgac aacacgatgt tgtttacaaa gattgccgaa ataaatatca
    10561 atatatattc catattcttt tcttatttaa ttgaattagg ctttcttgaa actgttaatc
    10621 aacgcaatga ggtatcccaa agcgatgaaa gcgcccggag ccaatacaaa caccaacatt
    10681 ccatattctt ccggcatgat ggtcaaatcg aagattttac cggttcccaa aaactcgcgg
    10741 acagcaccca gcaaggttag ggcgatggta aagccaagcc ccataccgat accgtcgaac
    10801 atagaagcaa ctgcgttatt cttggcagcg aaggcttcgg cacgtcccag tacaatacag
    10861 ttcactacaa tcaacggaat gaaaagaccg agtgtagcat acagtcccgg cacgtaagcc
    10921 tgcatcacca tttgaagcaa ggtcacgaag gatgcgatca ccacaataaa cgatgggata
    10981 cgcaccatgt ccggaatcag gttctttatt aaagagatca ccacattcga gcagatcaat
    11041 acgaacatgg tagccagtcc catacccata ccattgatag ccgatgatgt agtacccaat
    11101 gtaggacaca taccgagcag gagtacaaac gtaggattct ctttgataat cccgttcatc
    11161 attactttaa agttattcat atctgtctcc tttcttaatt agcactgact gaatcagtta
    11221 gttcaacttt gatcgtagct cccgtagcag cgtcagcagc atctgcgtcc gcgcctttcg
    11281 ctttttgaga agcaccggtt accccgttca cttccccgcc ttcggcctta taggcttgat
    11341 aagcagcatt cacggcattc aagaaagcgc gtgaagtaat ggtagaagct gtgatggcat
    11401 ccactgctcc cccatctttg ctgacggtca acggagcttc acccggattc atacccaaaa
    11461 tagatttcgt actctcttcg tgagatactg ccttttctcc tttcgcagga tcatacgctc
    11521 cgaaccattt gtcggcttta gagcccaatc ccggagtttc cgtgtgagcc aacagagagt
    11581 agttatagat ttttccttcg gcattaaagc ctaccagcac tttcagttca ccgccaaatc
    11641 ccattgattt agcttcgaca gcggttccta caagttcttc accgttctta gccggataaa
    11701 cgataaagtc aacattcttc tttccatctt tctcgctgaa gatcgtatcg ctttccgcta
    11761 ccggattatt ggtaaattcg ggaagaacct ttttcaaggc ctcgttcagt gtcttcgcgt
    11821 tcgcttcggc aatggggcct tttgtcagtt catttacata agccagcaac gcaacggaaa
    11881 tagcagtcac tcccgtaagt accagcaaca tattctttaa agatgattct aactttttca
    11941 tttcttcttc gctacctccc caaagcgttt tggtttacaa taggtgttaa tcagcggagt
    12001 gaacgcattc ataatcagga tggcgaacga cataccttcg ggataggcgc cgaacagacg
    12061 gataactacc gtcagcagac cgatacatac accatagatc agcatccctt tcttactcat
    12121 cggagaagtc acatagtcgg ttgccataaa gacagcaccc agcatcagac caccggaaag
    12181 caactgcaat accggagaaa cgtatttttc cggatctgcc aggtgcatga tgcctgcaaa
    12241 gacaaacaca gtagccagga tagacacagg aatatgccag gtaatgattt tcttccagag
    12301 catataaacg agtccgatca gcagagccag tgcactcact tcacccaagc atccgccatt
    12361 ctgtccgatc agcaaggtca atgcgtccgg aatctggctt aaagcggcag tgtcaccgta
    12421 aatggcttgc ttcatcaagg ccagcggagt ggcaccggtg gtagcatccg tataagcggt
    12481 caactgtccg actaccggcc agctggtcat ctgcaccggg aaagaaagca gcaggaatac
    12541 gcggcctgcc aatgccgggt tgaaaggatt gcagcccaat ccgccgaaag acattttgcc
    12601 tacaccgata gcaaacagtg caccgaggat gataatccag ataggcaagt tagacggtaa
    12661 attaaatgcc agcaacacac ctgtgatgat ggcagagccg tcgcagatgg tggtggtcgg
    12721 tttcttcatt aaatattttc cgatcgccca ttcgaagaac aaacaagccg caacggaagt
    12781 agccgtgaca atcagggcac ccagtccgaa gaaatagaga gacaccagaa aagccggaat
    12841 cagtgcaatc agcacgccat acatattttt ctgtacgctg tctccgccat gaacgtgggg
    12901 cgatagtgat acgattaatt tattttccat attcgttatt ttttagcttg acgtgcacga
    12961 atcatagctc ccactttgcc tttacccaga cgacaatagt cgagcagcgg acggttggca
    13021 ggacaagtga actggcaaga gccgcactcg atgcaatcca tgattctttc tttttccatt
    13081 gtttcaaaat ctccgttttc agacaaggct ccgagcaagt acggttccag tcccatcgga
    13141 caggcactca cgcacttcgc gcaacggatg caggtttgag cttcaccgcg tttggcttcc
    13201 ttccggttca taatcaggat gccggaactg cccttcgcag taggaacctc gatatttacg
    13261 agcgccttac ccatcatcgg accgccaccg atcaccttac ccgtatcttc gggcagacca
    13321 ccgcaagcgt caatcaactg tttcatcggt gtaccgatac gggccaggaa gttggacggc
    13381 ttcgcaaccg actttcccgt cacggtaatc acccgttcaa acaacggttt attcttctgc
    13441 acagcttcat aaacagcaaa cgccgttccc acgttctgca cgactgctcc cgtagagata
    13501 ggcaacgcac cgctcgccac ctgacgtttg gtgatcgcat cgatcagctg cttttcacct
    13561 ccttgcggat atttcacctt caagggaacg acttcgatgc ctgcatagct ggaagctact
    13621 ttagtcatca gttcgatagc atcgggctta ttattttcga ttccgataaa tgccttattc
    13681 actttcaccg ctttcatcag gatggaaaca cctaccatga tttcttccgc gtgttccagc
    13741 atcagctgat ggtcggcagt caaataaggt tcacattcta cggcattgat aatcacacat
    13801 tcagctttaa aagaaggagg aggacaaagt ttcacctgtg tagggaaaca agcaccgccc
    13861 agaccaacga ttccggcatc ggcaattttc ttcacgatct cttctgccgg aagttcacat
    13921 tccttcacca gtgtggcgct acggtcgatt gtttcttccc attcgtcgcc ttccacatcg
    13981 ataaagatag caggtttcgc ataaccgctg gcatcgacaa tagtatcaat cttcgccact
    14041 ttaccactga ccgaagagtg aattgccgcc gaaacaaagc cggcaggttc agcaatttta
    14101 gtgcctacct ttaccacatc ccctttcgct acaaccggtt ttgcaggcgc accaatgtgc
    14161 tgccccagca aaataacagc ctttgcagga acttccgctg tgataatagg ttgatgtgcc
    14221 gacaatttat tttcgtgtgg atgaactcca ccaattgaaa atgtctttaa catacagttc
    14281 tgtattttat tctgttatta ttctgttact ttcggagctt ctgtagcctt ttcagcagga
    14341 gtttccactt ttgccgccgg tgcaggagtt tccaccgctt ctttagaaac agcagccggt
    14401 tttggagcag ccggagcttc ttctttcggt ttcctcggcg ggaaattcaa ttcgataatg
    14461 gtattctgcg gacagacttc cacacatttc cggcaagatt tgcacttgtg cggatcgatg
    14521 taagccaagt tattctccaa cgtgatagct tcgaacggac aagtcttcac gcatttgcca
    14581 cagccgatac aactcaccgt acaagccttg cgcgccacag ctcccttgtc tttattcaca
    14641 caagagatat acacacggcg tgatttcttt ccttgcggac ggatttcgat gatcgccttc
    14701 ggacaagcct tcacacaggc accgcaagcg gtacatttcg cttcatccac ttccggaagt
    14761 cctgtttcag gattcatgtg gatggcatcg aactggcagg cagccacaca gtcaccacac
    14821 cccagacatc cgtaactaca acccgtttcc ccaccataga gcgaagcggc aatagcgcaa
    14881 ctcttcgcac cgtcgtactg attaatacgc ggacgattca tacacgttcc gttacatctt
    14941 accactgcta ccatcggttc agcttctccg gctgcaagcc ctaggatatc agcaatttgt
    15001 gccatgacag gctgtccgcc tacggggcag aatttaccat ccagcgaacc ggctttgacg
    15061 caagcgtcgg caaagccgct acaaccggga tagccacatc caccacaatt agcctgggga
    15121 agcacttctc ccacctgggc aatccgcggg tcttcataca cggcaaattt cttggaagcc
    15181 acataaagaa tagcggccag cacgagcgct atagctccca atgaaatcac tgcaatcaga
    15241 atcaaattca taatgttttt agttatttat tggttttata gtaaatgaaa attgttgttt
    15301 gagtcgcgtt ttgttaagcc ataaaacgaa ataataaggt ataaggacag ccagagaaag
    15361 aagagctgca tacagttcat tctctatcaa tgccatcaaa aaaaacaacg aaaatataag
    15421 aagtacgaaa ggaaatacga aagccaacaa taccgccatc atgcccatcg acgtttcgcc
    15481 gaccaccatc accttctctc ccacctgata ggaagaagct gcggtatcta tgatatctat
    15541 gattttgtcc ttactatccg ccgaggaaca atgccccttt gcgctacatg ccgcacaagc
    15601 cgatgtctgg acaatcctca ccgacagatg agaaccctgt atgttttcca caatacctag
    15661 atgctttata gtattattcg tcattttgca aactccgcat tacaaatcgc ggcaaattta
    15721 atcattattt gtgaactacg aagcattcct caaacttttt ctacctaata aaatgttatt
    15781 ttttgtgttt tcgttatcgc acacggaaaa ggtatggcta ccatttgata tttcccaaga
    15841 atgacaaata gacatcctaa acaaaaaaat cccggccgtt tttatttatt cagccgggat
    15901 tttctatcaa ttatttcacg gattactcca ctatcctctt cttgtagtag cgcagataca
    15961 ttctcaccaa cgtattcaaa atcagttcaa tctcctcttc gttgtaggca ttcaaacaga
    16021 gattcattac ttttatataa tcgttcaatg ggagatttag ccctttttta tgccattcaa
    16081 aacatcatgt cccataccca gggtctcgca tacatactca tttttcaatt tcgcacgttt
    16141 aagcaactca ttaatataag ctcccaaatc actgcaacaa accgttttct ttttcatctt
    16201 tgttttttgt tgttaaatac acactttaat aattaaatat tttaactttt atcctcacat
    16261 atcagggtag agtctatttt gttattacta ccttcatgcc gtgtttttga aacaccctca
    16321 tattttttgc aaaaataaac attttaactt ataacaaaaa gaaaatgatg tcaaacaact
    16381 acagaatgtc ctattttatg ccacctatcg ctcccatcaa agacaaacaa ggccgactga
    16441 tgactcctcc cacgcttatc cccttctgcg aagtctccat cgaacaagtt ttccaaatga
    16501 ttacttgcaa tgagaatctc aaaaccctga ccgcacaagt acggaatgcc acagatatac
    16561 gagccgccaa agcatcattg cttccgtatg tgaccccttg cggcacattc acccgccgta
    16621 gctgtaagga tttcgtctcc ccgtctcatc tggtgatagt agatgtggac ggtctccact
    16681 cttatcagga agcagtagaa atgcgacgta tgctctatga cgatcctctc ctacaacctg
    16741 tactcacctt tatcagcccc agcggactgg gtgtaaaggc atttgttcct tgccattatt
    16801 cccccacgat aaatgatgcc caaaatatca cagacaacat gagttgggcg atgcggtacg
    16861 tagagacggc atacaatacg gtaacagcgg tttcttccga aacgaaatcc aaagtagatt
    16921 tctccggcaa agacctcgtg agatcctgtt tccttagtta cgacccggaa gcattgttta
    16981 gaaccaagta aacgagaata attaaacatt attttataaa aatcaaaaca tgaccgatat
    17041 tgaatcttta tgccgtctca ccgaagcagt cgaagcggca ggagcggaca ttgctcccac
    17101 ctatcttgaa tacgtacaat tgtcatttgc catcgcaacg gattgcggtg aagcaggacg
    17161 tgactttttc catcgcctgt gccgggtgtc tcccaagtat cagcgcgaac atgccgaacg
    17221 ggtattctcc aacgcactcc acacccaacg tggagaagtg cacttgggca ccgctttcca
    17281 cctggccgaa gcgacgggag taagcatctg catagaagaa atgcccaaac atcccacagg
    17341 tacaaaaggt acagcaggta cagcacgcaa atttcccaca cacacgggcg cgcataataa
    17401 ggtgggaaat gacaatatct ccgatgatag agaaggggaa gaagaactat taccgggcag
    17461 tgaaccgcaa catcaattgc ccacttttcc ggaaaacgac tggccggaat ttttgcaacg
    17521 tatcataaaa gccgggagca gcccaataca acacgacatc atgttattgg gagcgctcac
    17581 tgccctgggt gcttgtatgt cgcgccacgt gcgatgccta tatggcggca aataccatca
    17641 ccccagcctc caatgtttcg tagtggctcc ttcggcttcc ggcaaaggta tcctttccta
    17701 catccgctta ctcgtggaac ctatccacga cgagatccgc aaagaagtga ccatacagat
    17761 gaaagcatac aaaaaagaga aagccgagta cgatgcaatg ggaaaagaac gaaccaaaaa
    17821 ggaggctcca caaatgcccc ctaacaggat gttcctcatt tcgggcaaca acaccggtac
    17881 gggtatccta caaaacatca tggactccga cggaaccgga cttatctgcg aagcggaagc
    17941 ggacaccctt tccaccgcca tcggatcgga ccacggtcat tggagcgata ccctgcgcaa
    18001 agcattcgac cacgaccgct tgtcctacaa ccgccgcacc gaccaggaat accgggaagt
    18061 gaagaaaagc tatctttccg tcctgatttc gggtacgccg tcgcaggtgc aaactttcat
    18121 tccgacggca gaagacggat catactcccg ccaattatat tattacatgt gcggaatcag
    18181 taaatggatc agccaattta tggacaacga gatagattgg gaggagatat tcaccgctat
    18241 gggactggaa tggaaagaaa agttgagcgt gataaaaacg cacggcattc ataccctgca
    18301 acttacggat gaacaaaaag aagaaatcga caccgtcttt tccgacttgt ttgaacgctc
    18361 cagtgtagct aatggaaggg aaatgtatag ttttgtggca cgtctggccg tcaatctatg
    18421 cagaatcatg tcggaagtag ccgtattgcg tgccctcgaa agcccgcagc cctacgactt
    18481 caagacctct cccacctctc ctttcacacc ggacaaggag attcctacgg acaaccgcaa
    18541 agatgacatc atcactcgtt gggatgtatc catttcacag gaagactttc atgctgtgct
    18601 tagccttgcg gagcctctct actgtcatgc cacgcatatt ctatcgttcc tccccagtac
    18661 agaaatcagc catcgtccta atgccgatcg tgattatctt ttccagaaac tgggtgatga
    18721 atttactcgt acccagttac tggaagaagc agttgccatg ggaattaaag aaaacacagc
    18781 cctcacttgg ctgaaacggc tcaccaaaca cggaaaatta atcagtatgg acggtaaagg
    18841 gttgtatgcg cgtgcgtgtg tgtatgagtg aaccggaaaa agtgtaccta ctgtacctgt
    18901 tttacttacg gatgcagtag tcatttcaat taccacatcc gttttgactg aaacaatcgt
    18961 ttgtcctgca taaagcatcg ctttaggagg tgtaaagcta agctttagac atcgtaaagc
    19021 ggtgctttat acaccataaa gcgacgcttt atttaaggct ctcctaaagc atccacaatg
    19081 actctcacct ccaacggtgt gaatgagcgt cgctttgatt cgtagcctaa gtcgtacagg
    19141 cgttgtagaa gtccgggaca caaagagatc catttcttca tttttcgata ggcagcgatg
    19201 tcagttagtt gcggagaata gagttgcgcc agttccatgc gcccgtaagc acgtatttta
    19261 aattcactca tgatggatat atttctgatt tactgttaca aaaataacaa aaaacgacta
    19321 tataaccaac gtttttccat tgaataaccg actataatga caaataaccg accgctacca
    19381 gacacaaccg tgcacagctg atttccggga gatccggagt agtatttttg tatcgtcgaa
    19441 agggaaaaga atccccggac aatatgttta accctttaat ttattgtttt atgattcgtt
    19501 acaaaattta tcagaaccag cagaagaaag gcttgaatgc gggtaagtgg ttcgcccgtg
    19561 cagtaagcga cgagacgttt gatttggcaa agcttgccga acatatgtcg aagcacaatt
    19621 caccgtattc cggtggtgtc atcaaaggtg tgctttcgga tatggtagat tgcatcaaag
    19681 aattgttgct agacggcaag tgtgtgaaaa ttgatgatct tgccattttt ggtgtgggta
    19741 ttcgcagtaa ggcagccgat acgctggaag agttctcgtt ggagaagaat attagcggca
    19801 tgcgtctgaa agcccgtgcc accggtaatc tgtcgaccaa taatctgaaa ctcgatagcc
    19861 agttgaagca gcaggcggaa tatcagaaac cgacaactgc cggaggaggt tctgattcgg
    19921 gtgacaaccc tgatccgaaa ccggatggag gtggcgaagc gcctgacccg gctgcctaaa
    19981 agattcacca cagactacac agatttccac agattatatt gaattggtag ttgtaaagta
    20041 gtcgattatt tatctgtgtg agtctgtgta aatctgtggt aaacctatgg caaacctaca
    20101 gtaaatctgt ggtaaatctg tggtaaaaga aaactattat taatttattt aaaacctgtt
    20161 attgtatgag taaatcatca tctccccgct ctgtatggag cttagtcctc aaaatcatta
    20221 tcactgtagc caccgccatc ggaggtgtgt tcggaataca aagttgcatg taaccccatg
    20281 cggactatta cattaattat cattcattgc agtgccacgc cggaaggaaa gtccctttcg
    20341 gcggaggctt gccgacagga tcatatcttg caccgtggtt tccgtgatat tggctatcat
    20401 ttttacatca ctcgtgatgg ggagattcac cggggacgtg cgttagaaaa ggtcggggca
    20461 cactgccgta atcataacac ccattcgata ggtgtttgtt atgagggagg attggatgcg
    20521 aacggaaaac cgaaagatac gcgtacactg gaacaaaaag gagctttgct tgctttgttg
    20581 agggagttga aaaggcagtt tccaaaagcg ttgattgtgg gacaccggga cttgaatcca
    20641 atgaaaggat gtccgtgctt tgatgcggtg aaagagtatt cccaagtaat ttcttatcaa
    20701 aagtagcttc ttttagattt ccaccacggc ttattgtata aaaaaatatc aacgatcttc
    20761 acagacagtt ggtatttttt ggaaatcata ttagtgttaa cactaatatg aagagcgaga
    20821 ttaggacaat accactatat tgctcctaat ctactaaatg tagggattca tgtttgtcac
    20881 atgaatctag ggacctacat ttttccatct cattgtaaat attcaattat aacataacgt
    20941 attaaaaagc actttcagta cttcctattc atttcatctg tttttcatcg tttaacgagc
    21001 ataagctcca tctttagcct caaagatgac agatggttca atcacttcca cagtatgcca
    21061 tgcaccctta ggtatctgac aaccatactt ggtttctgta ggattgagat ggatacgctg
    21121 tacttctcga tactcaacct tacgagctac atcttgtaca tttaccccct tctgaaaatc
    21181 atccgtatcc ttctcatacg aaactacttc ctcataaatt acttcgtcca acttaccaca
    21241 caggcagatt actgtttcgg tagtatcttc atgtcgatgg ataggcacct tagtttctgg
    21301 caacaatgcg tttagcatac gttgactggt atcggcagat gaagtgcgta ggtcgaagtt
    21361 ctgacgcaaa cgtggattct ccatagcttg ctcaaataac ttatctaaaa attctttatc
    21421 aaattccata atcgttattg tttcaatgat ataagatatt cttcatgtaa atgatagttt
    21481 tttttcatga ataatatgta agcaacagcc aatacagctg atacacccac cagatataac
    21541 caatgagcaa tcactgtatc gggacaaaga tagataaatc caagagaaat cactaactgc
    21601 ataaccgtat acaacaatgc aacttttaca tgccccactt tcaactcatt agccataatc
    21661 tgataagcat gcttacgatg tgcctcgccc aaattttcgt gcaacataat acgatgtaca
    21721 atagtcagac aaccatccac accatatacc aacaggaata tcagccaagt aatatccgtt
    21781 gtctcgatca tcacattacc taacagaaac agtatgataa aagcaatgcc gatagagccg
    21841 acatcccctg caaagcattt cgctttaccc ttcggacgga aattgaaaat acaaaacacc
    21901 aatgaagcaa gaatcgttga tatgatcaaa ctctgttcta caaaaatatc atccatattc
    21961 accagagcca acggtatcaa tacagccaaa gagtatcctg ctgtgatacc attgattcca
    22021 tccatgaagt ttattacatt cgtggcaccg acatagacta ttagtgctaa tagtattacc
    22081 caccacattg accaatgcaa tatgccaagc tgatagaacg ccattgcggc agctgcaaat
    22141 tgagcaacca atcttacaga gtccggcagt gaatggatgt catctacaaa gctaatgctt
    22201 gctacaagtg tcaggcctag tagaaaccaa ggatattgaa atccgaagaa ggcgctccaa
    22261 atccatacgc caatcaaaaa gattatacct ccgccacgca atacaatcgt ggagtgtgat
    22321 gaacgttcgt tgggtttgtc aataatgtta aaatggtcag ccaccttgaa ataacataac
    22381 tctaatgcca atagaatcac aaaaataatt ccgtaagtca agtatgcatt cataatcatt
    22441 ctactgctta aaacttctaa tagtgtccat caatccatcc ttcgctctta ccggcatccg
    22501 cgtaatgcca agggcagcct tgatcttagc attactcact acatagtttt ctgtgagttt
    22561 ctgcattcga agaggattga gcggaagatg aaaccaacca cccacttttg caactccgtt
    22621 catcagacct ttcggaatgc accatatatg agctttctta ccaagagcct cacaaataac
    22681 ttgaatgagt tcattagttg aaagagcttc atcgtctccc atatgataaa tacctgaagg
    22741 tacattctta gttaaaaatc cgtcaattac tacacaaaga tttccaatac tggtaaacga
    22801 acggcgattc tcaaaagcac caagaggcca tggaatcccc ttgctcacta ctccataaag
    22861 aagattgagg ttacccttgt ttccaggacc atgaatcata caaggacgta taatgtacac
    22921 attcttccct tttacaaggg aatcgctatc atcaaaattg tgataaggac gtttgagagc
    22981 ttcaggggca aaatgcccga ttatgtaatc ctccgcttta attttactct ctccataagg
    23041 acctacggga gtgggaacgc attcttctgt aaggcatttg ccttccactt tgtcagaagc
    23101 actctttact gtagagaaaa atataaactt ttttgcagat tcattggaaa gaaaccaatc
    23161 gaaaatacgt tgagtaagac ctgtatttac cttgaaatac acatccgctg cactcttgtt
    23221 ccgagtatca tgtgccttac cagcaagatg gataacagca tcaatctgcg gcaaatcaat
    23281 accacccaga tcatcccata aaaaagtctt tactatacct tccttctcag gagccacaat
    23341 gtccagacca tatattgtat tctcaggcga gagtgctttt actaaatttg agccgacgaa
    23401 accgtggact ccggtgatga ggatattcat aactaaaact ctttaactaa ttcaatatat
    23461 cggtcacata tctgcggcca tgtataatta tcttcgacga tttgacgtgc agttttacct
    23521 tgaactttca gtgtgttaaa atccttttca atcgctatca tattagcgat cacttcctcc
    23581 acattcttta cagtactcca aagcccaatc tcgtattttt caagtacctc ttgaattgac
    23641 ggaatacgtg taactacagg aatcttacca tatgacatcc cttctaacaa tgctatcgga
    23701 agcccctctg acgaagacac aaggcaatac gccatacaat ttttaagcaa tgctatttta
    23761 gcatctccat atacaattcc aggaaaaata atatttttgc acccctttgc acgttcaaca
    23821 atggtacgac cataagcatt attaatatct ccaccgataa ccaactgata atttacatga
    23881 ttatgccttt tgaatgcatc aatcaggacc tcatagttct taatcggatc aatgcgaccg
    23941 atagtcagaa agaattttcc aacttgtatt tcattctttt caagaatatc cgtatttaat
    24001 tctttattta tgggcaagaa tacaccacaa ggaagaacct tacaactttt gtgatacctg
    24061 ttgtacacct cttttgcttt agtacagcta acggtaacca catttttagt gaaagccaaa
    24121 gctaacctca ttgaagccat aagaagtttc ttcatcatct ttccatgttt cgggctatct
    24181 tccgcaaggc tatgaataat agcacttgat ttcataccaa acaaacgtac aatcagtgaa
    24241 ggaatcactg aaaatgtaac cgtttgatac attaccatat ctatttcctt cctatgcttg
    24301 atcaaatatg gtaatgattt tagatacaaa acaggaatac tggtcatcgt atttccccaa
    24361 gtcctatact gcttaatttt cacccctttg taatcagtta ccttattgca tgatccaaaa
    24421 ctcatcacaa acgactcaaa acctcttttc ttcagttcaa gagccaaatt ataagtatat
    24481 gagttcactc cgttcggttc ctcatgtgca cctatgaata ctgttctcat ctattatttt
    24541 ccctctatca aatccaaata tcgtttctcg aaaatctcca tagaatagtt ctcgcgaaga
    24601 ttctgattgc tcctcactcc catttgattc ctgagttcta ctgaatcaag caacttacat
    24661 aaagaagtag ttagtcccgt aacatcacca attggatgca agtaaccatt cacaccatca
    24721 attactaaat gatcattatc tccaacgtta gtagcaacca ccggcaaact ccaattcaaa
    24781 gcctccataa tactattgct tgtaccctca aatagactag tagatatata tatgtcggca
    24841 ttacgttcaa gttctgatac attattcggt ttgatatgga tatcagttct atccttgatg
    24901 ccatacagtt caacccattc acgaatctgc gcttcaagca ctccatagcc tacaatacag
    24961 aggcgataat cttttctatc aagcaatgaa atacttttaa taagagtttc gtaatctttt
    25021 tgagggtcga agcgaccaac tgtaatgatt gtcctttgag aatgattgtc tcttataatt
    25081 ggttcggcaa tatccgggaa gcaattagga atgacaatat tcttgtcttt ccgaaaaccg
    25141 aacttctcaa aataatcagc cccagaataa cagttgtaaa tggtcgctgt agcccaatga
    25201 ttatgagccc atttctctat caacatctta ctccttggaa gtcttgagtt a
//
