LOCUS       gnlProkkaGPBMDOCB_9    12506 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPBMDOCB_9.
ACCESSION   gnlProkkaGPBMDOCB_9
VERSION     gnlProkkaGPBMDOCB_9
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:27:50
            Original ID  :: gnl|Prokka|GPBMDOCB_9
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 36726
            Orig. end    :: 49232
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12506
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12506
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12506
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(183..995)
                     /locus_tag="ctg9_25"
                     /transl_table=11
                     /translation="MISITRDKRMLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTP
                     YSGDEAEKVRRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHG
                     VDALITREPGYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEF
                     GTSGEDVVACIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANR
                     MQILAFGVPSGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(992..2158)
                     /locus_tag="ctg9_26"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(2248..2817)
                     /locus_tag="ctg9_27"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(2877..3413)
                     /locus_tag="ctg9_28"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3454..4998)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_29"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5191..5415)
                     /locus_tag="ctg9_30"
                     /transl_table=11
                     /translation="MMEKKRIGLNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             5688..6521
                     /locus_tag="ctg9_31"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             complement(6614..6859)
                     /locus_tag="ctg9_32"
                     /transl_table=11
                     /translation="MLVMMAFNACNAVWQALLSHLLLLSPENIHGCLLTFPCVFLLLYI
                     PLVHLFHPQSPYSSKVQEKGGRGDCDKYAMGIFLIS"
     CDS             7053..8564
                     /locus_tag="ctg9_33"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8638..9702
                     /locus_tag="ctg9_34"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9724..10011
                     /locus_tag="ctg9_35"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_36"
                     /sec_met_domain="PF05402 (E-value: 3.7e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.4e-09, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10393..11781)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_37"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(12072..12467)
                     /locus_tag="ctg9_38"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
ORIGIN
        1 gtagtcaagt cttctgtgaa agtatttatt tctttccaaa gtccatcgca gtaagcagta
       61 ttcttcactg ctgcatatac ggctgctccg gcaaaaacag ggcaggcgtt ctttatttcc
      121 tgagatactt ttatttcaaa catacttcta ttcaagttta tatcaactta cgttcaagtc
      181 tattatttat gaatcatgat ccccgacaga atccgtccgg acttaatgcc caaacgcctt
      241 gccgagaaaa actcgtcgtg atgaatatac gtacatatcc gggcaagctc cacctggccg
      301 gacggcacac cgaaagcaag gatttgcatc cggttcgctt cccacaagtc gatatgatgt
      361 tttccggttt cctctttcct gatagaaata cgaggcatat caaaaccatt cttctgaaat
      421 gcttcgtaca cttcctcacc cacttcaaaa gaagccaatg agatactcgg accgatacag
      481 gcaactacat cttctccact tgtgccaaac tccttttcca tccgcaacaa agtatcacgc
      541 acgatgtatg ctaccgtccc tctccatccg gcatgaatgg cagctatggc actatgtttc
      601 ttatcatata tcaacacagg aacacaatcc gcagtagaaa tacaaagaca atatcccggc
      661 tcgcgggtaa tcaaagcatc cactccgtgc agcatctcct gtcgttgttg agacgaagcc
      721 gataaataag catccccgat cagcaggcaa ttcgtctcat gagtctgcac aggaatcacc
      781 agttcttcgg gtgtctgcga cattccttcc atcagaagcg tttgattccg ccggaccttt
      841 tccgcctcgt ctccactgta gggcgtacag ttgaatgacg cataatttcc ttcgctgcac
      901 cctccctgcc gggtagttac aaaatgagaa atgttggagt atgagcttaa cgactcatac
      961 cccaacattc ttttatctct tgtgattgaa atcatttttc ttcccaatcc tcttcttcgt
     1021 attcgtagtc gagatcatca tcgtcgtcgt cagcgtcttc ctcatattca tagtcaagtt
     1081 cttcatcctc gcccatgtcc ttgagttcct gctgcagacg ggtcacgtct ttcggacggt
     1141 gaacaatgtc ttctatctta ttactttcct tgttcagttc ctcccacaga atgtctttca
     1201 acactgagat tcccaaaccg gaaacagaag aaatgaatat atgcggaaca ccctcgggca
     1261 atgtcggttc aatctcgtcc atcagctcct gatcgagcat atcgctcttc gtgatagcca
     1321 gcacacgttg tttgtccagc atttcgggat tgaacgtacg cagctcattc agcaatactt
     1381 catactcctt gcggatatca tcgctatctg ccggaaccat gaacaacagc aacgagttac
     1441 gctcgatatg acgcagaaac cgcagtccca atccttttcc ctgactggct ccctcgatga
     1501 tgcccggtat gtccgccatc acgaatgact ttccatcgcg ataggaaaca attcccagat
     1561 tcggttcgag tgtcgtaaac gggtaatcgg caatcttcgg tttcgcagcc gaaatagcag
     1621 aaagcaacgt agactttccc gcattcggga aacctaccag ccctacatct gccaacagtt
     1681 tcagctccat gatcaccgtc atttcctgca tcggttcgcc cggctgcgca aagcgcggag
     1741 cctgacgggt agccgtcttg aaatgactgt tgccctgacc gccacgaccg cctttcagca
     1801 agatcacttc ctgtccgtcg tccgtcacat cgcaaaggta ttctccggtt tcggcgttat
     1861 acactaccgt tccgcagggt acttcgatca ctttatccgc accgtctttt ccgaaactac
     1921 ggttcttgct gcccgattcg ccatgacctg ccatcgcatg acggtcatac ttcaagtgaa
     1981 gcaatgtcca gtaattacgg ttaccgcgca agataatatg gcctcctctt ccaccatcgc
     2041 ccccatcggg acctccgtta ggacaatatt tctcgcgcct catgtgcgta gagcctcttc
     2101 cgcccttgcc cgagcgacag tatatcttta cgtaatcaac aaaattcgat tcagccatat
     2161 ttttttaaag agttaaagta gtcagtagtt agagcagtta attagaacac tccggctact
     2221 gacttattta tttataatat tgtattatta caatttatct actgcttcgc agatttcagc
     2281 gaagatacct tccatagtac ccaagccgtt gatgtgttgg tatttctttt cgttcttgta
     2341 ccagtcgatc agtggagcag tctgtgaatg atatacatgc agacgtttct tgattgtttc
     2401 ttcgttatca tcagcacgac cggaatcctt gccacgttta atgagacgta ccatcagttc
     2461 ttcttccgga acatccaagt caaccattac agaaacgtcc tgtcctcttt ctgccaacat
     2521 tttctttaat gcttctgctt gtgcaattgt tcttgggaaa ccgtcgaaaa ttaccccttt
     2581 gctatctttg aagctgtcga atacgcttgc cagaatatca atcattaatt catcaggaat
     2641 caattgacct tggtcgatat aacctttagc tgttttaccc agttctgtgc cattcttgat
     2701 ttcagcacgc aatacatctc ctgtcgagat gtgattgatt ccatactttt ctacgatacg
     2761 ttcgctctgt gttccttttc ctgaacccgg agcaccgaaa attacgatgt tcaacatttt
     2821 gttatttaca atttaacgat ttactattta ccatttaaac tggtacctat ttaatattaa
     2881 tctactactg tataaatatc gggataatta cgtccgaaac catcataatc cagtccgtaa
     2941 cctacgataa agtcgttcgg gatttccatc gctacatatt caatgttgag gtttaccttg
     3001 agcttttcag gtttcaccaa cagagaagcg atatgaatag cttcgggatt gcgtgtacct
     3061 aatgtttcga gcagtcgctg catcgtcagt cctgtgtcta cgatatcttc tacgatcaca
     3121 atggtacgtc cggcaatgtc ttcattcagg ccgattacct ctttaatcac tccggtggaa
     3181 gtgatgccct gataagacgc caacttcaca aatgagattt cacaagggat ggtgatgtgc
     3241 ttcagtaaat cagcagtaaa catgaacgaa ccgttcaaca cactaaggaa aagcggattc
     3301 ttacctgcca aatcgcggtt gatttcgttc gctacgcgaa tcacttcttt ctgaatttct
     3361 tgttccttaa tggaaacggt aaacaatttg tcttttatct gaatggtatc cataaccggt
     3421 aatttaaaaa taaccttgca aaaatacgat tttttattct accccgtgca tcatcttctg
     3481 taatttcttc gagagaagga acagaatcag tgaagcaaca ccggacataa tgacgaacag
     3541 catgaagaag tcatacatgg tagcaatctg ataaccaagg attgatttca cttttccgtc
     3601 ttcgggatag aggccactca gcatacctgc aaatttattt gcggtggcgg tagaaagata
     3661 ccagatcccc atcatcaagg aggcgaaacg taacggactc aacttattaa ccatagaaag
     3721 cccgataggt gacagagcga tttctcccat tgtatgaata aaataaagtc ctgtcagcca
     3781 gatcatgctc acctttactc ccggaatagc atctttcact ccaaaacaga tgaagagata
     3841 accaagagaa agcagtaaca gaccgattgc ctgtttggta ggggaagccg gttccatgtt
     3901 tcgcttattc agaaagctcc atataccggg cataatatag gcaaggatca ctacaaaaag
     3961 cggattgaat gactggaacc acgaagccgg catctcccag ccgaaaatgc tgcggtcagt
     4021 ctgttcggaa gcgaataatg tcagagaagc tcctgcctgc tcgtaagctg cccagaagaa
     4081 aatgacgaag aaagctacga tatagattac gaaaatacgg ctacgttcta ctttggtcaa
     4141 tgaaccatcc agcagaatga gcactggaaa gacaatacaa gccgtaaaga tacccacact
     4201 aatccagtca tcgctaaagg catagctaaa aaaggctatt aaggcaaccg taagggcagt
     4261 aatgatgatg atattacgta ctttggtacg tttgtccatc ttcggatgtg aaatatgttc
     4321 ggctttatcc tccttttttt cacgtctggc gtcggggacg ataccaatcg gttcaccgga
     4381 aggagagaaa aggtatttat tcttctgagt ttcaaagagg acaacagtga acagcgtcat
     4441 gattccggat gcgaggaatc cccatttaaa gtcctgcgga ttccctgtgt ctcccaagaa
     4501 accgcaaatc aaaggagcgg cgaaagaacc tacattaaca cccatataga aaatggtgta
     4561 tgcagcatcc aaccgtttgt ccccgggttc atataattgc ccgacgagcg aagaaacggt
     4621 aggcttaaag caaccgttac ctaaaatcat gaatccgagc ccgccataca tcagccagtg
     4681 ggcaaggtct gtattgttca gtgaagaggc actcataaac atcaggaact gaccgactgc
     4741 catcatcacc gctccccaaa ataccgaacg acggatgccc caatatttat cggcaatgta
     4801 tccgccgatc aacggagtca gatagaccag tccggtgtag ctaccgtaga tagaggccgc
     4861 cgcttcttta tcaaaaagca atgcctgcgt cagaaagagg ataaagatag cacgcatacc
     4921 gtagtaactg aaacgttctg ccgtgctcgt tgcgaaaatt aggtaaaggc ctttcggatg
     4981 ccctttcaat gaactcatga attatgtgtt tagtagttta tggggcgcaa aggtactaaa
     5041 aagtagatta aatgcctcaa aaaagaagat tcttatggaa tagaaaaata caggatggcg
     5101 tgcaagaagt ctcagttacc caccttatta tgttttcaac agtgtaaata atcaagtgga
     5161 tattctcctt aaatgtgggt cagtccccat ttatccaaag gtaaattcaa cattctcaat
     5221 actggcatag agcattcctt ctttttttct aagcaggatt ttgttttccc ttgccagcca
     5281 accgatagca atcgctacat cctcgaacgt caaacctaac tcatggcaca aagtgaacat
     5341 agactgttcg cccttttcat ttaagatgcg ccatactttc ccggcattca agccaattct
     5401 tttcttttcc atcatgcaaa ctttagaaga ttaaacaatt tatatttata atctaaacat
     5461 tgtgagcaca ggagaataac gtaaagcaca ttactgcact acaaagatat catttttttc
     5521 gaaaaaagca aataatcaaa gcattagctg ctattattag ttacattcta atcatttatg
     5581 ccgatctctg ctaaaaaata gcacaaataa agaaacagtt caattctttt tcataagttt
     5641 gcagacgaga actaaactaa tatcgcacat ttaaaacttt aattagcatg actaccaaaa
     5701 aactaacagg aatactttcg ttattccttt gtattatttg cctcgtgagc tgtaatgaca
     5761 atgatgacaa cttttctcca atcactctgg aatatgaaga tcctcaaatt aagttcgaca
     5821 acgagagccg ttcttacaca ctgactccgt tcagcaaaga aacgacacca ctcttcatca
     5881 agggtggaga cggaacttac aaagtgacca atgagaatga gaaagtggta caagtaaact
     5941 accacaacgg aagtttaaca ttgaaggcaa aggaaatagg acgcgcatcc atcaagatag
     6001 aagacagttc gaataatatg tatatactgt ctgtcgttgt aaaatatcgt actcttactc
     6061 ataaggcgtt tacagcaaaa gtcattgtga agggagacga gcttacatct gaagaacaca
     6121 ctgagttaat gaacaaagtg ggcaattcat atccgattaa taaatatgta tttactttta
     6181 tgaatgcgga agacagcaaa ggaacagtag atttgtatta ttcagataat aacatgaaaa
     6241 caggcaactt tgaaaaagaa catatagtgc tggatgaaga aaatgccatt cccatcaaag
     6301 gtgaatacaa attgagtgag tattaccgta taacaatcaa agaagataat ggcaaagtta
     6361 ttgatacttt ctatattacc aagaactttc taccactcct caatacaaga atgaatgctc
     6421 atccgttaat tcagtactgt tttgtcagag atttaaccgc acagtacaaa caagattacc
     6481 ttgcactgga aaatgcatat ctgattcaaa tagcagaatg agaactacac tgattttctt
     6541 ctttagcaga gtgaatagag tatttattat atgagcaaac tccccattag atttagcaaa
     6601 aaacaataag ctattagcta atcaagaata tgcccatagc atatttatca caatcacctc
     6661 ttccaccctt ttcctgaacc tttgatgaat aaggcgattg cgggtgaaag aggtgaacca
     6721 gaggaatata cagtagtaga aacacgcatg ggaaggttaa caaacagcca tgaatgttct
     6781 ccggagagag taaaagtaaa tgagataaca atgcttgcca tactgcgtta caagcattga
     6841 aagccatcat aacaagcatt gatatctacc ataacaatca ttaatatctg acttctcaac
     6901 tattaataac tgacacatca actattaata cctgacaact caagtattaa tacctgaagt
     6961 tccttcccaa aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggaac
     7141 gtgccgcaca ggcgctgact aaagccatca ccaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgtcagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg actgatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcgctaatc aaaccacgcc aacaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcccgtg
     7861 cctgtctgcg atcgggagta ggtctgctga ccgtacacgc gccgttatgc aacaacgata
     7921 ttttgcaaac gtccgccccc gaagccatgg tagaaacgga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca
     8041 gcgaggaaac ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac
     8101 tggatgccga cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtcacctg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaacg tcccctacag cagtaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
     9361 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
     9481 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgcttat cattatgggc
     9961 gtactgatag gatgtgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatattg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
    10141 ctatcaggtt ccatacagcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggg atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
    10381 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
    10441 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
    10501 catcggcaag gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
    10561 gttcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
    10621 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
    10681 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
    10741 ccaccatata ttcagaatag gaagagcgaa catagtgtgt acgaaaatca gcatcaccga
    10801 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tacaatgaac cgaacaatgg
    10861 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
    10921 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
    10981 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttagtaa tgatatatac
    11041 gatgtctttc atgcggaaag gttcttccgg ttccagtcct tccgcatcca gtgaagcatc
    11101 cagtttctta tcatagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
    11161 gagacagaac agaatcggag cgggaatatt ggtatggaat acgccgctct catccgtaga
    11221 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagttgttc caatacgcgc
    11281 ggtcgccatt tccagtccca tagcgagagc catctccttg cctttaaacc acttcacaat
    11341 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccaaagatgg cataacccaa
    11401 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
    11461 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
    11521 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
    11581 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
    11641 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
    11701 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgcggagt cattcagctt
    11761 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
    11821 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
    11881 gacatctgac cggatattcc tgtatgaaga agagcagacc gggcccaata ataaagacag
    11941 gcgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
    12001 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
    12061 ctgtcactga attattctgc tgcaggagca ggagtttcag tagccggagc ttccgttgct
    12121 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
    12181 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagctgca
    12241 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
    12301 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
    12361 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
    12421 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
    12481 gaattagcgt taataatcaa tttctc
//
