LOCUS       c00074_gnlPro..         3804 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FOGAMIMN_74.
ACCESSION   c00074_gnlPro..
VERSION     c00074_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 19:56:03
            Original ID  :: gnl|Prokka|FOGAMIMN_74
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3804
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3804
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3804]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3804
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3804
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3804
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..799)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_1"
                     /sec_met_domain="IlvN (E-value: 2.4e-49, bitscore: 155.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.7e-25, bitscore: 76.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMY"
     CDS             complement(841..1572)
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(1609..2163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_3"
                     /sec_met_domain="ALS_ss_C (E-value: 4.5e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSSIK
                     GINKFTITTIADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(2176..3804)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-51, bitscore:
                     162.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FGYPGGQAIPIYDSLYDYRDQLKHILVRHEQGATHAAQGYARVSG
                     KVGVTVVTSGPGATNTITGIADALMDSTPMVVIAGQVPSPLLGTDAFQEVDVIGITQPI
                     TKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLDLAKDAQVGLVDYEYQKVDYVRSYQ
                     PEPDIREERIEAAASLINNAKKPFCLVGQGVILGGAEEELKEFLLKNDIPAGSTVLGLS
                     ALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLD
                     IDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERKRPEWNAEFEPDEKEEYNKVIEKEL
                     YPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMG
                     FGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELGTIMQENLNVKIIVLNNNFLGMVRQ
                     WQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVDKREDLDEAIAEMLNHDGAYMLVAN
                     VETCGMVYPMVPAGGSVTNMILGDK"
ORIGIN
        1 catacatcca gtccataccg ttttctgcga acaacggcat caatgactga gtcagttctt
       61 ctactgtttc attgaatgct tcagaaggtt cgtgaccgtt ttcacgcaaa gtttcgtact
      121 gagccaacag taatccctgg atagctccca tcaaagtacc acgttcgccg gtcaggtcag
      181 aataaacttc tttcttgaat gttgtttcaa acaagtaacc agaaccaaca ccgataccca
      241 gtgcaatcac gcgatcccat gctttgcctg ttgcatcctg gaagattgcg tagcttgagt
      301 tcagaccacg cccctgcaag aacatacggc gcagtgaagt acctgaacct ttcggagcaa
      361 ccaggattac gtctacatca gcaggaggga tgatgtttgt acgttctttg taagtgatac
      421 cgaatccgtg agagaaatac aaagccttac ccggagtcag gtattttttg atgcgcggcc
      481 aaacttcaat ctgagcagca tctgaaagca gatactggat gatagttgct ttttcgcatg
      541 cttcttcgat atcgaacagt gtttcgcccg gtacccaacc gtcagcaacg gccttttccc
      601 aggtcttacc acctttacgt tgtcctacaa ttacgttaaa accgttgtcg cgcaggttca
      661 ggctctggcc aggaccttgt acgccgtaac ctattacagc gattgtttcg tctttcaata
      721 cttctcttgc cttttccaac ggaaattctt cgcgggttac tacgttttcg tcaacgccgc
      781 caaaattcat tactgccatt ttctttttac tattaaaatg tatataaaat aatttgtttt
      841 tcagatccag gtaacggcag cgcggctgat ggctttgccg tcgttacaga ttgccatatt
      901 atatttaccg ggggatactt cctggttatg gagagtcagc tccatcccat actttccttc
      961 ggactgataa gctatttcga aacggcttat ctctttttct cggaacagac tgatatcgaa
     1021 caagtcgagc aggtgttcca tgtatttgat actgttcagg tggccgttta cgtccaggtc
     1081 actgtacttc acacggtaag gttcgccgga agtgttgttt tccaccggag caattttacc
     1141 cggtttttca atcggacagg gacggtcggt gatataagca ctcaggccct ccacatcgag
     1201 caaggtcggg cggcgggttt ccatatcgat agccgcccag atagagcggg caaagccaaa
     1261 ggtcttgcct tcgccgttca ccagttcaaa gcaacggctg gtaaacaact taccgacctc
     1321 atccacccag gtatataaag ttacggattc agacatggca ggataagaag tcatctcgat
     1381 agccagacgg gaaagaaccc aggcggtatg cctttcggtc atatcgttat atccgaatcc
     1441 acggtcggcg gcatggcaag aagcagcatg caacaaataa gttccgatca tagggattgt
     1501 aatacgtccc cggaagtcca tcagataaga ctctgttacg aaatgaaatt ctcctacttt
     1561 gttcttctcc ataatttact ttatttacaa aatgtttcct tattattctc agacatgttt
     1621 ttcctgcaac ttcttttcca ttgcagataa catgtcgctc agacgttcta ccttactctt
     1681 cgttatagca acgcgtccgg aacggataaa ttgcaggaca ccgatcgtct cactcaattc
     1741 tttaaacaaa gcctgtgtct catcataatg accactcttt tccaacacca cacaatcctc
     1801 attcatttca aggatacggg cattgtactt acggatcaga tcctcaaccg tccccatctt
     1861 gataaagagt tcggtactca gtttataaag agcgatttcc tggtaaacca ggtcttcatc
     1921 cgtattataa taggctttca ggatatccac acgcttgtca atctgtttta cgaccttatc
     1981 gatcgtatcc tcgtcggcaa tggtagtaat tgtaaactta tttattccct ttatagaaga
     2041 gggagaaaca gaaagcgtct caatgttcag ttgccggcgc gtaaagataa cagttatctg
     2101 attcagaaga ccaacagtgt tttccgaaaa gataataacg gtatataatt gttttgtatt
     2161 catagtttct cctccttact tatcacccaa aatcatgttt gtcacgcttc ctccggccgg
     2221 aaccatcgga tataccatac cacaagtttc cacattggca accaacatat aggcaccatc
     2281 gtgattcaac atttcagcaa tcgcctcatc caagtcttcc cgtttatcta ccgcacggga
     2341 agcaatacca aaagccttgg ctatcgctac aaaatccgga ttcttcatga tggtattcga
     2401 ataccgttcg ttgaagaaca gctcctgcca ctggcgtacc attcccagga aattgttgtt
     2461 aagaacgatg atctttacat tcagattttc ctgcatgata gttcccaact cctggatagt
     2521 catctggata ccaccgtcgc cggtaaagaa acagaccgta cggtcaggcg ctcccagctt
     2581 cgctccaatg gcggcgggaa ggccaaagcc catcgttccc aaacctcctg aagtaactac
     2641 gctgcgtgtt tgtttatatt tgaaatagcg aacacccatc atctggttct gacctacatc
     2701 cgtaaccaga atcgcatcat tatcggttgc ttcggaaacc ttacggacta cttcgcccat
     2761 ttttagttgg ccttcggtag gatagagttc tttttctatt accttattat attcctcttt
     2821 ttcatccggt tcgaattcag cattccattc cggacgcttc cgttcttcca gtaaagccgt
     2881 aatcatcgga atcgtatgct tggcatttcc cagcactttc acgtcgaccg gcacattctt
     2941 tccgatctcc gaattgtcga tatccaagtg gataatcttt gcctgcttgg cataagtctt
     3001 caggtcgccg gttacacggt catcgaaacg cataccgata gcaatcaaca cgtcacattc
     3061 gtttgtcttg cggttcggtc cgacatttcc atgcatcccc aacatacctt tatttaatgg
     3121 gaagtccgaa ggtaatgcag acaagcccaa tacggtagaa ccggctggta tatcgttttt
     3181 caacaagaat tctttcagtt cttcttcggc tcctcccagg ataaccccct gccctaccag
     3241 acagaatggc tttttggcat tatttatcaa tgaagcagcc gcctcgatac gttcctccct
     3301 gatatccggt tcaggctggt aactacgaac ataatccact ttctgatact cataatctac
     3361 caaacccacc tgtgcatctt tcgccaaatc cagtaccaca ggtcccgggc gaccggtcga
     3421 tgcgatatag aaagcacggg aaacggccca agcaatttct tccgggcggc gtatctggta
     3481 agcccatttg gtaatcggtt gtgtgatacc gatcacatca acttcctgga aagcatctgt
     3541 tccaagcagc ggagacggaa cctggccggc aatcaccacc atcggtgtac tgtccatcag
     3601 cgcatcggca ataccagtga tggtattggt tgccccggga cccgaagtaa ccaccgttac
     3661 tcccactttt ccggaaacac gggcatatcc ctgtgcagca tgtgttgcac cttgttcgtg
     3721 gcgcaccaga atatgtttta actgatctct gtaatcgtat aaactatcgt aaattggtat
     3781 cgcctgccca cccggataac cgaa
//
