LOCUS       c00011_gnlPro..        13404 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHIMMPOH_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 22:47:09
            Original ID  :: gnl|Prokka|MHIMMPOH_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13404
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13404
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3404](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3404
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13404
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13404
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             3..3404
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="PFOR_II (E-value: 1.4e-19, bitscore: 60.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.3e-70, bitscore: 226.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.5e-32, bitscore: 102.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.8e-13, bitscore:
                     38.4, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2e-12, bitscore: 37.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.8e-08, bitscore: 22.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-05, bitscore: 14.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.7e-26, bitscore: 80.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMI
                     PNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLA
                     GVAHLATIKARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLVDQEALAEFRARALNPMN
                     PVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAER
                     VIIAMGSVTEAAREAIDYLTSQGEKVGLVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRT
                     KEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIIAVFKNLAMPMPKNH
                     FTIGIVDDVTFTSLPQEAEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHC
                     QAYFSYDSKKSGGFTCSHLRFGDDPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNG
                     SFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIAQEIGLGNRTNTILQSAFF
                     RITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDD
                     AKVENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWN
                     AENCIQCNKCAYVCPHASIRPFVLDAEEQKGANFEMLKAVGKQFDGMTFRIQVDVLDCL
                     GCGNCADICPGNPKKGGKALTMKHLESQLAQADNWTYCADNVKSKQHLVDIKANVKNSQ
                     FATPLFEFSGACSGCGETPYVKLISQLYGDREMVANATGCSSIYSGSVPSTPYTTNAKG
                     HGPAWANSLFEDFCEFGLGMELANEKMRARIVKLFNEILAADNAPAEAKEVLKAWIENM
                     YDADKTKELAPQIEAIIEQGIAAGCPISKELKGLTQYLVKRSQWIIGGDGASYDIGYGG
                     LDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRVRKKDLGLMATTY
                     GYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAV
                     KCGYWHLWRYNPALEAEGKNPFTLDSKEPNWDDFKGFLKGEVRYASVMKQYPAEAEELF
                     QAAEDNAKWRYNNYKRLANQAWGAAE"
     CDS             3608..4111
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MNITIRPTRLEELGQVMPFYERARRFMAANGNANQWINGYPSPDD
                     IRQDIENGSSYVFVNENQELEGCFAFIRGEDPNYKVIKDGAWLNDAPYGVIHRIASGGR
                     VKGLMDLCLEWCLSHCPNLRVDTHRDNKVLQNILLKNGFTYCGIIYVKNGTERLAYQRT
                     AVTR"
     CDS             complement(4153..4980)
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="LLLLAVMCVACNPDSGKKKISIAYANWLEGIAMSHLAKVVLEEKG
                     YEVELLNADVAPVFASVSRKKADVFMDAWLPVTMKDYIDQYGDQIEFIGEVYDSARVGL
                     VVPQYVTIDSIGELAAHKGQFSSEIVGIDAGAGIMKTTDKAIGDYGLDGYKLLTSSSST
                     MLASLQKAMEKEAWIVITGWTPHWMFDRYPLKFLHDPKGTYGNVESIYVVGWKGFTEKD
                     PFAAKFFSNIKFTTEEISSLMKALKDARMDEEELVRKWRDEHRELVESWIPES"
     CDS             complement(5027..5851)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 96; E-value: 7.4e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.4e-30, bitscore:
                     96.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETLINWMMIHFSTFFDALNLGIGSFINGFQHILFGIP
                     FYLTIAAMVLLAWAKAGRGVAVFTLLGLLLIYGMGFWEATMQTLALVLSSTCLALIVGV
                     PIGVWTANSNRAEKVIHPILDLMQTMPAFVYLIPAVLFFGLGVVPGVFATIIFAMPPVI
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMVRRKDKK"
     CDS             complement(5848..7074)
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MSKITIKDLYLIFGNDKQHALRMLKEEKSKSEILKATGCTVAVKD
                     ANLSIREGEIFVIMGLSGSGKSTLLRCINRLIKPTSGEVIINGRDISNVTDKELLRIRR
                     KELAMVFQHFGLLPHRSVLHNIAFGLELQGVKKQEREQRAMESMQLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRIQMQDELLTLQSKMKKTIVFITH
                     DLNEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANAYVERFVQSVDRSKIITAASVMVD
                     KPLVARLKKEGPEVLIRKMLERNLTVLPVVDANNVLVGEVRLKDLLRLRQDQVKSIESV
                     VREEVHSVLGDTILEDILPLMTKTNSPIWVVNETREFQGVVPLSSLIYEVTGKNKQEIN
                     EIIQNAIEL"
     CDS             complement(7409..7753)
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MKDYKENKSNLSETFCNEVYSVVREIPAGSVTTYGDIAALLGMPQ
                     YSRMVGRALRQVPAGLNLPCHRVVNAIGRLVPGWDEQRRLLDAEGVSFRKNGCVDLRLH
                     RWRDDSVLAD"
     CDS             complement(7784..10507)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_7"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.2e-16, bitscore:
                     49.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILFLLGLMLSGLLVSCSPDAPRYTIGVSQCSDDTWRHKMNDE
                     IQREALFYGGVKVETRTAHDDSRRQIEDIRYFIRQKVDLLIVAANEGMALTPVVEEAFD
                     KGIPVIMVDRRILSDKYTAYIGADNYELGKAVGNYIAHRLKGRGKVVELSGLVGSTPAI
                     ERHQGFMSAISQYPDMTLLASEDAGWLQQPAEAKMDSLLQRFPEIDAVYGMNDRMAAGA
                     FRAAGRRGREKEMIFVGIDALPGKGNGVELVLDSVLDATFIYPTEGDKVVQLAMDILEK
                     KPFERETKLKTAVVDAVNAHVMELQTNHIGELDGKIETLNDRVGIYLSRVATQRIVLYG
                     GLIILLLIVGLLIVVYKSLRSKNRLNRELSRQKEQLEEQRDQLIELSHQLEEATHAKLV
                     FFTNISHDFRTPLTLVADPVEQLLADPSLEGDRRRMLLLVQRNVQILLRLVNQILDFRR
                     YETGKMDFTPVPLDLLQCFVEWNDSFQAAARRKHIHFSFDSMPDTDYHTQADAEKLERI
                     YFNLLANAFKFTPENGKVTVRLAALKKDSVPFFRFTVANTGSLISAEHIRSIFDRFYKI
                     DRHHTGSGIGLALVKAFVEIHGGSISVESDERLGTVFTVDLPVRTCEEGTYVVTAPMEE
                     SAPDRVDSLLREDEAENLNDPSKPSVLVIDDNADIRAYVHTLLNSEYSIIEAADGTEGI
                     RKAMKYVPDVIISDVMMPGIDGIECCRRLKGELQTCHIPVILLTACSLDEQRIQGYAGG
                     ADSYISKPFSSQLLLTRIRNLIESRQRMKQFFGDRQTLAKEDICDMDKDFVERFKSLIE
                     VKMGDSELNVEDLGKEMGLSRVQLYRKIKSLTNYAPNELLRMARLKKAASLLASSDMTI
                     AEVGYEVGFTSPSYFAKCYKEQFGESPTEFLKRSGL"
     CDS             complement(10694..11584)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MNSIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGNDELGDEILEIFREKQLKHQLERVNYPTGTVQVTLDNGGVPCYDIKEGVAWDNIPFT
                     DDLKRLALSTRAVCFGSLAQRDEVSRATINRFLDTMPDMEGQLKIFDINLRQNFYTKEV
                     LRESFRKCNVLKINDEELIIISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGTVSFQETPKVPVADTVGAGDSFTAAFCSSVLKGKSIPEAHRLAVEVSAYVCTQSG
                     AMPVLPEALRNRLND"
     CDS             complement(11616..12782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 112.6; E-value: 6.3e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_9"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-35, bitscore: 112.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNNSYMKLIPVMLCFFAMGFVDLVGIASNYVKADLGLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDSYLLMLVSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASTLTFGQFVKAIASFLAPYIAMWGAIEAIPT
                     FDLGWRVLFPIYMVVAVVAILLLNATQITEEPEEGKPSTFGQCLALLGKPFILLSFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAAKTF
                     FAISVLCMLAAMFGLFVFQDQAMIYVCIALIGFGNSNVFPIIFSQAMLYMPDKKNEVSG
                     LMIMGLFGGTIFPLAMGVASDAVGQSGAVAVMLVGVLYLMFYTWRIKK"
ORIGIN
        1 agaacatctt cggcgaaaca gtattggtac aggaaatgca atctgaaggt ggtgcagccg
       61 gtgctgttca cggttctctt caggccggtg cactgactac tacttacact gcttctcagg
      121 gtcttctttt gatgatcccg aatatgtata agattgccgg tgaattcctg ccttgcgtat
      181 tccatgtatc tgctcgtaca ctggcttctc acgcactgtg tattttcggt gaccaccagg
      241 acgtaatgtc tgcgcgccag acaggtttcg ctatgttggc tgaaggttct gtacaggaag
      301 tgatggactt ggccggtgtt gcacaccttg ccacaatcaa agcccgtgtt cctttcatga
      361 acttcttcga tggtttccgt acttcacacg aaatccagaa gatcgaaatg ctagaaaatg
      421 aagatctcgc tccgttggtt gaccaggaag cgcttgccga attccgtgca cgtgcgctga
      481 atccgatgaa tccggttgcc cgtggtatgg ccgaaaaccc tgaccacttc ttccagcacc
      541 gcgaatcatg caacaactac tatgaagctg ttcccgccat cgtagaggaa tacatgaatg
      601 aaatttctaa gatcacaggc cgcaaatacg gtttgttcga ttactacgga gcagaagatg
      661 cagaacgcgt aattatcgct atgggttctg taacagaagc tgcccgcgaa gctatcgact
      721 atctgacaag ccaaggagaa aaagtcggtt tggttgcagt tcacctgtac cgcccgttct
      781 ctgctaaaca cttcctggcc gccgtaccta aaacagctaa aacaatcgca gtactcgatc
      841 gcacaaaaga accgggtgct aacggtgaac ctctgtatct ggatgttaaa gactgcttct
      901 atggcgcaga aaatgctccg gttatcgtag gcggtcgtta cggtctgggt tctaaagata
      961 ctactccggc acaaatcatc gccgtattca agaatctggc tatgccgatg ccgaagaacc
     1021 acttcacaat cggtatcgta gacgatgtaa ccttcacttc tcttcctcag gaagcagaaa
     1081 tcgctctggg tggcgaaggt atgttcgaag ctaaattcta cggcttgggt gctgacggta
     1141 cagtaggtgc caacaagaac tcagtgaaaa ttatcggtga caacacagat aaacactgtc
     1201 aggcatactt ctcttacgac tctaagaagt caggaggttt cacttgctct cacctgcgtt
     1261 tcggtgacga tcctatccgt tctacctatc tggtaaacac tccgaacttc gtggcttgcc
     1321 acgttcaggc ttacctgcac atgtacgacg taacccgtgg tctgcgtaag aacggttcgt
     1381 tcttgctgaa cactatctgg gaaggcgaag agctggctaa gaacctgcct aacaaggtga
     1441 agaaatactt tgcacagaac aatatctctg tatattatat caacgcaact cagattgcac
     1501 aggaaatagg tttgggcaac cgtaccaata ctatccttca gtctgcattc ttccgtatca
     1561 caggtgtaat ccctgtagac caggctgtag aacagatgaa gaagtttatc gtgaagtctt
     1621 acggtaagaa gggtgaagac gttgtaaaca agaactacgc agccgttgac cgcggtggcg
     1681 aatacaagac tttgactgtt gacccggctt gggctaacct gccggacgat gccaaggttg
     1741 aaaacaacga cccggcattc atcaacgaag tagttcgccc tatcaatgct caggacggag
     1801 acttactgcc ggtatctgca ttcaaaggta tcgaagacgg aacctggtat cagggaactt
     1861 ctaaatacga aaaacgcggt gtagctgctt tcgtaccgga atggaacgca gaaaactgta
     1921 tccagtgtaa caagtgtgct tacgtttgtc ctcacgcttc tatccgtccg ttcgtactcg
     1981 acgctgaaga gcagaagggt gccaacttcg agatgctgaa agctgtaggt aaacaattcg
     2041 acggtatgac attccgtatc caggttgacg ttctcgactg tctgggttgc ggtaactgtg
     2101 ccgacatctg tccgggtaac ccgaagaagg gtggcaaggc tctgactatg aaacaccttg
     2161 aaagccaatt ggctcaagct gataactgga cttactgtgc agacaacgtg aagagcaaac
     2221 aacacctggt agacatcaag gctaacgtga agaactctca gttcgctact ccgttgttcg
     2281 agttctcagg agcttgttct ggttgtggtg aaactccgta tgtgaaactg atttctcagt
     2341 tgtacggtga tcgcgagatg gttgccaacg ctaccggatg ttcttctatc tattccggtt
     2401 cagtaccttc aactccatat actaccaacg caaaaggaca cggtccggct tgggctaact
     2461 cactgttcga agacttctgt gagtttggtt taggtatgga actggctaac gaaaagatgc
     2521 gtgcacgtat cgtgaagttg ttcaacgaaa tcctggcagc cgacaatgct cctgcagaag
     2581 ctaaggaagt attgaaagca tggatcgaaa acatgtacga tgcagataag accaaagaac
     2641 tggctccgca gatcgaagca atcatcgaac aaggtatcgc agcaggttgc ccgatcagca
     2701 aagagctgaa gggcctgact caatatctgg tgaaacgcag ccagtggatc atcggtggtg
     2761 acggtgcttc ttacgatatc ggttacggcg gtctcgacca cgttatcgct tcaggtaaag
     2821 acgttaacat tctggttctg gatacagagg tttactctaa cacaggcggt cagtcttcta
     2881 aggctactcc ggtgggtgct atcgctaagt tcgctgcttc cggtaagcgc gtacgtaaaa
     2941 aagacctcgg tctgatggct actacttacg gttatgtata tgttgcacag atcgctatgg
     3001 gtgctgatca ggctcagact ctgaaagcta tccgcgaagc tgaagcatat cccggaccat
     3061 cactcatcat cgcttacgct ccgtgtatca accacggtct gaaagccggt atgggtaaga
     3121 gccaggaaga agaagaaaaa gctgttaagt gcggttactg gcacttgtgg cgttacaacc
     3181 cggctctgga agcagaaggc aagaatccgt tcacgctgga tagcaaagaa ccgaattggg
     3241 atgacttcaa aggcttcctg aaaggcgagg ttcgttatgc atcagttatg aaacagtatc
     3301 ctgcagaagc agaagaactg ttccaggcag ctgaagacaa cgcaaaatgg cgttacaaca
     3361 actacaagcg tctggctaac caagcttggg gtgcagctga ataatctttg atcagataat
     3421 aactttcgaa gggggaaggg actaaaagag gttctttccc cctttttgaa caaaaatgaa
     3481 taggtttcac cacagattac acggattaac acagaactct taatcctata tattgacgaa
     3541 gataaattat taatctgtgt taatccgtgt aatctgtggt gcccccccca aaaaaaacgg
     3601 aataatcatg aatataacca tacgccccac ccggcttgaa gaactcggcc aagtgatgcc
     3661 attctacgaa cgtgcccgcc gcttcatggc tgccaatggc aatgccaacc agtggatcaa
     3721 cggatacccc tcccctgatg atatccggca agatatcgaa aacgggagca gctatgtgtt
     3781 tgtaaacgaa aatcaagagt tagaaggctg ttttgctttc atccggggag aagatcccaa
     3841 ctacaaagtc atcaaagacg gcgcctggct caacgatgcc ccttacgggg tgatccatcg
     3901 catcgcatcc ggcggacggg taaagggatt gatggactta tgcctggaat ggtgtttgtc
     3961 ccactgtccg aacctgcgtg tagacactca ccgtgacaat aaagtactcc aaaacattct
     4021 cctaaagaac ggtttcacct attgtggcat tatttatgtg aaaaacggta cggaacgact
     4081 tgcctaccaa cgcactgccg ttacccgata gacagaaatc agaagttgga ttcccggaca
     4141 cacatatacc gcttatgatt cagggatcca gctttctacc agttcccgat gttcgtcgcg
     4201 ccattttcgg acaagctctt cttcgtccat gcgtgcatct ttaagtgctt tcatcaacga
     4261 actaatctct tctgtagtga atttaatatt gctgaaaaac tttgccgcaa aaggatcttt
     4321 ctccgtaaat cctttccatc cgacgacata gatagattcc acattcccat aagtaccttt
     4381 cggatcatgc aggaacttca atggatagcg gtcgaacatc caatgcggag tccatccggt
     4441 gatgacgatc cacgcctcct tctccatagc cttctgcaaa gaagccaaca tagtagagct
     4501 gctcgaggtg agtaatttat aaccatcgag accataatcc ccgatagcct tatcggtagt
     4561 tttcataata ccggctccgg catcgatccc gacaatctcg gaagagaact gccctttgtg
     4621 ggcggcaagt tccccaatcg aatcgatagt gacatattga ggtaccacca gccctaccct
     4681 cgcgctatca tatacctctc cgataaactc tatctgatca ccgtattgat ctatataatc
     4741 cttcattgtc acaggtaacc aggcatccat aaacacatct gccttcttac gggaaaccga
     4801 tgcaaagacg ggagctacat ctgcattcag caactccact tcgtacccct tctcttccag
     4861 caccacttta gccagatgac tcatggcaat tccttccagc cagttggcat aggcaatgct
     4921 tatcttcttt ttcccgctat ccgggttaca ggctacgcac atcacagcca gtagcaacaa
     4981 acttcctatt attctatatt ttcgcatatc ctattctttc tcctttctat tttttgtcct
     5041 tccgacggac cattccctga gtaatccggt ctaaaataat tgccaatatg acaacggcta
     5101 tacctccttc aaagcccagc ccgattttca tctgggtgat acctttcaaa acgatttctc
     5161 ctaaaccgcc ggcagcaatc atagccgcaa tgacaaccat ggaaagagac atcataatcg
     5221 tctggttcac tccggtcagg atggtgggca aagcaagggg caactgtact ttataaagca
     5281 actgccatcg ggtagctccg aacgagcgtg aagcctctac cacattcttt ggcacctgac
     5341 ggatgccaag ccctgtaagg cgaatcaccg gaggcatcgc aaagatgatt gtagcaaata
     5401 ctcccggaac cactcccagg ccgaaaaaca aaacagcagg aatcagatag acgaaggctg
     5461 gcatggtctg catcaagtcg agaatgggat gtatcacctt ctcggcacga ttgctgtttg
     5521 ccgtccatac tccgatggga acccctacga taagggccag gcaggtggat gacagaacca
     5581 gtgccaatgt ctgcatagtg gcttcccaga atcccatacc ataaataagc aacaagccta
     5641 aaagggtgaa aactgcaaca ccgcgtccgg ctttcgccca tgccagcagc accattgccg
     5701 caatggtcag atagaaagga atgccgaaca gtatgtgctg gaatccatta ataaaactac
     5761 cgatgcctaa gttgagtgca tcgaaaaaag tggagaagtg tatcatcatc cagttgatga
     5821 gcgtctcaat atattgtcct atgttgatca taattctatt gcattttgaa tgatttcatt
     5881 gatttcttgt ttgttctttc cggttacctc gtaaataagc gatgacaacg gaacaactcc
     5941 ctgaaactca cgggtctcgt tcactaccca gataggcgaa ttggtttttg tcatcaacgg
     6001 taaaatatct tccagtatcg tatctcccaa caccgaatgc acttcctccc ggacaaccga
     6061 ctcgatcgac ttcacctggt cctgacgcaa tcggagcaaa tctttcagcc ggacctctcc
     6121 cacaagcaca ttgtttgcat cgaccacagg caacacagtc aggttacgct cgagcatttt
     6181 acgaatcaac acctccggtc cctctttctt caatcgggcc acaaggggtt tatctaccat
     6241 cactgatgca gcggtaataa tcttgctacg gtccacactc tgcacaaagc gctctacata
     6301 agcattggcc ggttctgtca ggatctcttc cgaagtgcct acctgtacca cctcaccatc
     6361 tttcatgata gcaatccggt cgcccaattt aatggcttca ttcaaatcgt gggtaataaa
     6421 cacaatggtc ttcttcatct tagattgtaa ggtcagcaat tcatcctgca tctgtatgcg
     6481 aatcaaagga tcgagagcgg aaaaagcctc atccatcagc agcacctcag gatcattggc
     6541 caacgcacgg gccaaaccga cacgttgctg catacctccc gacagttcgc cgaccatctg
     6601 gttctcgtag cccttcagtc ctaccagttg catgctttcc atcgcccgct gctctcgctc
     6661 ctgtttcttt actccttgca gttccagtcc gaaagctata ttatgcaaca ccgagcgatg
     6721 gggcaacaac ccaaaatgct ggaacaccat agccagctct tttcttcgga tacggagcaa
     6781 ttctttatca gtgacgttag aaatatctct cccgttaatg atcacttcgc ctgaggtcgg
     6841 ttttatcaat cggttgatgc aacgcagcaa agttgatttt ccacttcccg aaagtcccat
     6901 aatcacaaat atttctcctt cccggataga taggtttgca tcttttacgg ccaccgtaca
     6961 tccggtagcc ttcaatatct cacttttgct cttttcttcc ttcaacatgc gtaaagcatg
     7021 ctgtttgtca ttgccaaaaa tgagatacaa gtctttaatc gttattttac tcatacataa
     7081 tagggtttag attattaaaa aaacagatcg ggtgacctat acacacgaaa acaagcactt
     7141 ctttatagca aggaagttga tgccggggaa gcgacggttc cgccgttccc cggtcaaata
     7201 tgatttcttt acccgattat tacagacagg attcctgtca acagatagtt tactatatcc
     7261 cgaaagtcaa tttcacatct gcacacagct atcttcccaa gatgcgtatg cagacaatta
     7321 agtaaacaag ccgaacgttc aaatggttca tcgcattatt tccggcaggc gcattacacg
     7381 tacataaacc cctacaaaag agtcagtatc aatcggccag cacactgtca tccctccacc
     7441 tgtgaagcct gaggtcgaca catccatttt tacggaaaga aacaccttcg gcatccagca
     7501 gccgccgctg ctcgtcccat ccgggcacta atcggcctat ggcattgact acccgatgac
     7561 aagggaggtt taaaccggca ggcacctgcc tcaaggcacg ccccaccatg cgtgaatatt
     7621 gcggcatccc gagcaaagcg gcaatatcgc cataagtagt aacactaccg gcaggaatct
     7681 cacgcacgac actgtatact tcattacaaa aagtttcgga caaattagat ttattttctt
     7741 tataatcttt catggatgta ttgcttttat acagtgagtt cctttataat ccgcttctct
     7801 tcaggaactc cgtcggactt tcaccgaact gctccttgta acacttcgca aagtacgaag
     7861 gagatgtgaa tcccacttca tatccgacct ccgctatcgt catatccgaa gaagccaaca
     7921 gagatgccgc ctttttaaga cgtgccatgc ggagcagctc attaggagcg tagttcgtga
     7981 gcgacttgat cttccgataa agctgaaccc ggctcaaccc catctccttg cccagatctt
     8041 ccacattaag ttccgaatca cccatcttca cctcgatcag cgacttgaac ctctccacaa
     8101 aatctttatc catatcgcaa atgtcttctt tcgccagcgt ctgccggtcg ccaaagaact
     8161 gcttcatacg ctgcctcgat tcaatcagat ttcggatacg ggtcaacaag agttgcgaac
     8221 tgaacggttt tgagatgtat gaatcggctc ctccggcata tccctggatg cgttgctcat
     8281 cgagcgaaca ggccgtaagc aggataacgg gaatgtggca ggtttgcagt tctcccttca
     8341 gcctccgaca acactctatg ccatcgatcc ccggcatcat cacatccgaa ataatcacat
     8401 cggggacgta cttcatcgct ttacggattc cttcggtacc atccgcagct tcaataatcg
     8461 aatactccga attgagcaac gtatgcacat aagcacggat gtcggcatta tcgtcgatca
     8521 caaggacaga aggtttggac ggatcattca ggttttccgc ttcatcctcg cggagcaggc
     8581 tgtccacccg gtccggagca gactcctcca tcggagcagt caccacatag gttccctctt
     8641 cacaagtccg caccggcaga tcgacagtaa agacagttcc caaccgttcg tcactctcca
     8701 cactaatact tccgccatgt atctcgacaa atgctttcac caatgccaac ccgatgccgg
     8761 aaccggtatg atgcctgtcg attttataga accgatcgaa aatgctgcga atgtgttcag
     8821 ccgaaatcag gctgccggta ttggccaccg tgaaacggaa gaaaggcacg ctgtccttct
     8881 tcagagccgc aagacggaca gtgacctttc cattctccgg agtgaattta aaggcatttg
     8941 ccaacaaatt gaagtaaatg cgttccagct tctccgcatc tgcctgtgtg tgataatccg
     9001 tatcgggcat actgtcgaaa gagaagtgga tatgtttccg ccgggcagcc gcctgaaacg
     9061 aatcattcca ctctacaaag cattgcaaca ggtcgagcgg aaccggtgta aagtccattt
     9121 ttccggtctc gtatctgcga aaatcaagta tttgattgac caaacgcaat aggatctgca
     9181 cattgcgttg caccagcaac aacattctac gccggtcacc ttccagcgac ggatctgcca
     9241 gtagctgttc cacaggatcg gcaaccaaag tgagaggagt acggaaatca tgtgaaatgt
     9301 tggtgaagaa aaccagtttg gcatgggtag cctcttccaa ctgatgggaa agttcgatca
     9361 gctgatctct ttgctcttcc aactgctcct tttgccgtga cagctcccgg ttcaggcgat
     9421 tcttggaacg aagcgattta tatactacta tcaacaaccc gacaatcagc agcaggatga
     9481 tcaggcctcc gtacaacact atccgttgcg tagccaccct cgagagatat atccccacac
     9541 ggtcgttcag tgtctcgatc tttccgtcca gctcaccgat atggtttgtc tgcaactcca
     9601 tcacatgcgc gtttaccgca tcgactacag ccgtcttcaa cttcgtttcc cgttcaaaag
     9661 gtttcttttc gagaatatcc attgccagtt gcaccacttt atccccttcg gtgggataga
     9721 taaaggtagc atccagtacg ctgtcgagca ccagttccac tccattcccc ttacccggca
     9781 gggcatcgat gcccacaaaa atcatctcct tctcccgtcc tcgacgaccg gcagcccgaa
     9841 aagcccctgc agccatacgg tcattcattc catatacggc atcgatctcc ggaaaacgtt
     9901 gcaaaaggga gtccatcttt gcctcggcag gttgttgcag ccatcctgca tcttcgctgg
     9961 caagcaaggt catgtccgga tattggctga tggcactcat aaacccctga tggcgttcga
    10021 tagcgggagt agaaccgaca agtccgctca gttcgactac ttttccgcgc cctttcaggc
    10081 gatgggctat gtaattgccg acggctttgc ctaactcata attgtcggct ccgatgtatg
    10141 cggtatattt atcggaaagt attctgcggt ctaccataat caccggtatt cctttatcga
    10201 aagcctcctc gacaaccgga gtgagagcca ttccttcatt ggctgccaca atcagcaggt
    10261 caaccttctg ccggatgaag tatcgtatat cttctatctg acgccggcta tcgtcatgcg
    10321 ccgtacgtgt ctctactttg actcctccgt agaacaaggc ttcccgctgt atctcgtcat
    10381 tcatcttgtg acgccaggtg tcgtcactgc attgtgacac accgatggta tatcggggag
    10441 catccggact gcacgagaca agcagtcccg acagcatcag tccgagtaag aaaagtatac
    10501 ggttcatggt cggttattac ataaaaggtt ccggaggcaa atataacaat ttccctccgg
    10561 aatctcccac ctgcttggtt taaaaccaaa gtctcgttgg tttaaaaaaa ggtgagttat
    10621 gaaacactct cctgatttta aaccaaacgg aactttctat taaccaatca ataaccctat
    10681 ataaaccaac acattagtca ttcaaacgat tcctcaaagc ctccggaagt acgggcatcg
    10741 ctccactttg ggtacatacg taagcagata cctctaccgc cagccgatgt gcctcaggga
    10801 tactctttcc ttttaaaaca gatgaacaaa aagccgctgt aaacgaatca cccgccccca
    10861 cagtatcggc aaccggaact ttcggtgtct cctggaaaga gaccgtaccg ggagtgaata
    10921 cataacttcc gttcgttccg caagtcagga tcagcatctt caggttgtac ttggccagca
    10981 gaatccaaca tttatcctgc aggtcaatgc cgggataacc gaacatgcgg ctgataatga
    11041 tcaattcctc atcattaatc ttcagcacat tgcacttccg gaaagattca cgcaagacct
    11101 ccttggtgta gaagttctga cgaaggttga tatcgaatat tttcaactgt ccttccatgt
    11161 cgggcatggt gtcgaggaag cggttgatag tggcacggct cacctcgtcg cgctgtgcca
    11221 acgagccgaa acagacagca cgtgtactca aagccagacg tttcaagtcg tctgtgaaag
    11281 gaatattatc ccatgccact ccctctttga tgtcataaca cggcactccg ccgttatcga
    11341 gagtcacctg caccgttccg gtcgggtagt tcaccctttc gagctggtgc ttcaactgtt
    11401 tctcccggaa tatttccaga atctcgtcac ccagttcgtc atttcctacc gcactgacaa
    11461 cgcggctgtc gaaaccaaac tgagacacat gataagcaaa attagccggg gctcccccga
    11521 ttttctttcc ttcgggcagc acatcccata gcgcttcgcc cattcctacg attatactgt
    11581 tcatggtatg aattaatttt tatctataaa tccggttatt tcttgattct ccatgtataa
    11641 aacatcagat agagtactcc gaccagcatc accgctaccg ctccgctttg tcccacagca
    11701 tccgaagcca ctcccattgc cagcgggaag atcgttccac cgaaaagtcc cataatcatc
    11761 aggccggaaa cctcgttctt cttgtccggc atatagagca ttgcctgcga gaaaatgatg
    11821 gggaatacat tagagttgcc aaacccgatc agggcaatac agacataaat catcgcctgg
    11881 tcctgaaaaa cgaacaaccc gaacatggcg gccagcatac acaacacact gatagcgaag
    11941 aaggttttag ccgccatctt ctgcaaaatg aaagctccca gaaaacaacc tgccgtacgg
    12001 aaaatgaagt aaagactggt cgcaaacccg gcatccgcca gagtcatgcc cagacgttcc
    12061 atcagaatct tcggtgctgt agtattggta cccacatcga tccccacatg acacataatg
    12121 cccaaaaacg agagcaggat gaagggttta cccagcaaag cgagacactg accgaaagtg
    12181 gaaggtttgc cctcttccgg ttcttcggtg atctgcgtgg cgttgagtaa caaaatagcg
    12241 actacagcca ccaccatata gatggggaac agcactctcc agcctaagtc gaaggtaggg
    12301 atggcctcaa tagctcccca catagcgata taaggggcta ggaaggaggc gatggccttt
    12361 acaaactgcc cgaaggtcag ggtacttgcc aagcgctcgc cgctcacgat attcgacagc
    12421 aacggattga gcgatgtctg catcaacgca ttgccaatgc cgagcaacga gaaagagacc
    12481 aacatcagca aatagctatc accaaagacc ggtagcagta atgatgcgaa agtgatcacc
    12541 agactgagca acacggtctt tttacgcccg atgcggttca tcagcatccc cgtaggtaca
    12601 gagaagatca ggaaccagaa gaaaacgagc gacggaaaga tgtttgcctg tgagtccgtc
    12661 agtcccaaat ctgctttgac gtagttggag gcaatgccca ccagatctac gaatcccatg
    12721 gcaaagaagc agagcatcac cgggatgagt ttcatgtaag agttgttttt ggtattttcc
    12781 atgatatgtt aatttaatga atgtctcaac gggaggcgat agaggaacta caacctgtat
    12841 atcttgcacc gatccacctt gaaggctccc ccacgactgt agaaactcat ctgattgtaa
    12901 ggagttgtag ggaatatcag gttcgtcata gcaatcttac ctccgttcag gaagatttct
    12961 accgagcatt tatctacaaa gatatccaat ttatagttac cggctttctg caccggagcc
    13021 caggtaccca aagcaaaatc gtctacataa ttaatagagt tctgtttccg gcgatcgtgt
    13081 gtctcgatgg catgcggggc actgtctttg ccgaagtcta cgatgccgct cttcgtacgg
    13141 tccatcacca actttttctc cggaaggctg atgtagatat ctacattctc ccctttttca
    13201 ttgaacagct tcagtcccat aatctcggca gagccggctg ccagttccaa ctctatttcg
    13261 taagcccctt tattatcgga caacaacgaa tcgacatgat aagcatcccc cacctcaaaa
    13321 gccggaatct cccgggattc tttacgcaat gacttggtct cttccaccgg ggcggcagcc
    13381 atatagatat ccccatcttg tgta
//
