LOCUS       c00023_gnlPro..        15679 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MOCBBIPD_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:35:08
            Original ID  :: gnl|Prokka|MOCBBIPD_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 83960
            Orig. end    :: 99639
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15679
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[93960:98724]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14764
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15679
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15679
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             473..1609
                     /locus_tag="ctg23_65"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNNADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPSKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
     CDS             1632..2645
                     /locus_tag="ctg23_66"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVMVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVAGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWFAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             2895..4163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_67"
                     /sec_met_domain="MFS_1 (E-value: 4.9e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             4218..5216
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_68"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.7e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(5320..5793)
                     /locus_tag="ctg23_69"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             5863..6861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg23_70"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.8e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             complement(6966..7718)
                     /locus_tag="ctg23_71"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             7906..8454
                     /locus_tag="ctg23_72"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8506..9768
                     /locus_tag="ctg23_73"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPTSGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSEIF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDASKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_74"
                     /sec_met_domain="Radical_SAM (E-value: 3.8e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(10731..12959)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_75"
                     /sec_met_domain="Gly_radical (E-value: 2.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13718..14764
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_76"
                     /sec_met_domain="Radical_SAM (E-value: 4.1e-10, bitscore:
                     32.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLNFISPNTLSLLTTYYCTAACKNCCFECNQERRGRMSFKQME
                     TYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAHKKGLITRVVTNGYWAVSYEKA
                     LGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRAAAKVDLPCLVNIETNPSSQFS
                     EEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRDTNYNELIKHRYVQRPIISHGC
                     NSLFESIPIDPEGNVYACCGLACRKAKFLKIGNMNTAGINKIYRRQFDDFLKVWAYVDG
                     PKFILNKIAMETGKNVEVNADMHNCEACLLLLNDPSKIEYIKNNISRYISEVVLKYNIK
                     QKKANYEK"
     CDS             14754..15545
                     /locus_tag="ctg23_77"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENLVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKDCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             15545..15679
                     /locus_tag="ctg23_78"
                     /transl_table=11
                     /translation="MSVYKSKFQPVMERWSLVLKMVLLTTGLMFLLRTFMLQSLQDQIA
                     "
ORIGIN
        1 aaagaatcgg acctaaatca ggtacgggac ggttacttgt gattgatggc gagcctcaaa
       61 gtattcatcc ggaaaccggg ccttactttg actatttcat tgtgcaggca tactctaacc
      121 ttgcgggtaa ttccgatgct aatcttgaca gacgtctggc tggtacgatt gccaacttta
      181 aaggaatact tcctccggag aaagtggcta atatgtacat cgttacggag aatttcgaat
      241 cttatgctcc gacaggagga ggtgattatg tagatcgtta cggaaacaaa atgagagcac
      301 ttgccggcat ggcacgctgg actccgacta ttgacggaaa acaggtacgg aagggtggag
      361 taggcaccta tcacatggaa tatgactatc cgggcgacat cgaatataag tacctgcgtg
      421 aagcaatcag aataatgaat cctgctgtaa aatgacttta aagaatttga ttatgaaaag
      481 aataacaata aaacaatgtt tgcttgcctg tttcgttctg ccgatgatcc tggcaggatg
      541 caacaatgcc gattaccagg ttatcgacaa tgcgatttat ttgaatgaag catccgagaa
      601 tggttcggca aaggttaccg ttgatcctga aaatgtaaca acaactactc tgaccgtacg
      661 tgtgggacag cctgtaaccg aaaatgtgac tgctgtcctg acggtagatc cttctattct
      721 taaagagtac aatgaagcta atgaaacttc gtacgaagtc cttcccgagc agtattttac
      781 ttatgacaaa gagataaaga tagcggcagg cgatgttagc gcaatcccca gtgagtttag
      841 agtgaaacct tattcaaacg aaaacggaga attgtatgct attccggtat ctctcacaga
      901 aattcaggga ccggtgtcca caatcgggct ttcgtcgaag tttatcattt tgctggataa
      961 gccgctgata cagtctgtac cgtttatgaa tacgaccaat gccgtgaagc cctccaagga
     1021 cgaattgtgg ggagtgacaa ccaatgaatg gtcactcgag gcttgggtac agatggacgg
     1081 attcgatatt aataatcagg ctatatttaa ttcgggcagc agcgaccacg aggtttatat
     1141 ccgtttcggt gacgctatga tcccttataa ttcattacag gtgaagacac ttggaagtca
     1201 ggtcaatacg gtgactttgt ttgagaagaa taagtggtat catctggcct tcgtttataa
     1261 ttcttccggg ttattgtcga tttatatcaa cggagtgctc gacgtgactc tgcagacaaa
     1321 gggtggcccg gttagattcg acaagatgaa catggtttcg agcggtagct acttccgcaa
     1381 caattgtcag atggcccagg tgcgtctttg gaagagcgca atcagccaga cgcaaattca
     1441 gtccaacatg tattttgccg tgaaacccgc cgatccgaac ctgataggct attggaaaat
     1501 ggatgaaggt aaaggaaatg cctttgccga ctgtaccgga cacggatacg atttggtggc
     1561 aggaggaact cttgtctgga aagagcatgt tcgttttgat aagcaataac tatgtaaaaa
     1621 gaagataaga tatgaataga catttgaatt ttgtgacctt aatctgcctg ataacaggct
     1681 ttgtatcgtt ggcttcgtgc agcaacgatg atgatgaaat ggacaaatat caaaagatat
     1741 atatcagaac gggagttgca ccgggggccg aaatgggtgc tgcggtaatg gtggattgtg
     1801 tgagcaattc ctctactgcc gaccgttctg attttgaaat acaattgtgt gccgtacagc
     1861 cggttacgcg ggatgtcact gccgctttgg gagtagatac gctgaaagtg gatacttaca
     1921 attctgccaa taagacgaaa tgtaagttgt tgccccaaga taattatacc attgaaacaa
     1981 gtgaagttgt cttaaaaacg ggacagacag tggccgattc atcttttcag gtcgttttga
     2041 agaatataga aaagttgact aatcctgacg gatatgtgct tcccgtgacg cttaaaggag
     2101 ttgcgggcat ggacgaacag gctgtcagta catctatgaa gacggtttat atccggattt
     2161 ataccagcgt gctttatacc agttatacga aacccgggaa ttggttcgct gtagatcgaa
     2221 gtgcgtggag tgtaagttgc agtaatgttt atgccgatga tgatgctaaa tatggtgcac
     2281 atctggctat tgacggtgag ataaatacta cttggtttac atggggagtg gctaatgccg
     2341 gagagtgttg gtggaatacg ctactggacc gacctgttac cttaaccgga ttttcggtca
     2401 ctaaacagag tgcctacggt tcgggttata atctgagaag tgctgagatt aaggttcgga
     2461 aagagggtga aaccgagtgg gttacttacc cgagagtctt gactttcaga aattttaaag
     2521 gggctgatcc gcaatatgcg gccatcgaac cacctatccc gaatgtaaag gaattcagaa
     2581 taaactgtct gactccggat aattataccg ggtttgctga gataaattta tatgtgaagc
     2641 aatagaggtg tttagattgt agataagggg gcgagaggca tcggggatga aagtcttcgg
     2701 tgcttctttg cgtgtgtcgt attgataaag tttaataaaa aaagggtgat agaggttagt
     2761 agttttcccg ggtgagttgt attattaaat aatgaaagca acttcttgtc gtaatcttgg
     2821 gttatgtttt taatatcccc tatctttgct tactggaatt gttaaccgat ggaattatta
     2881 taaaaaacta actgatgaat aaaaagccga taagccctgt atgttgggtg cctactgttt
     2941 actttgctat gggattgccg tttgtggccc tttcgatggt ttctgtcctt atgttttccg
     3001 atatggaagt gtcgaatgca cagattgctt tctggacttc tctcattatg cttccctgga
     3061 cattgaagcc tttatggagt ccgtttctgg aaatgtttaa aacgaaaaag tactttgttg
     3121 tcgctacgga aattattacc ggactggcat ttgcattggt agcactttcg ctgccgctgc
     3181 ccgacttttt tcgttatgcc atcgctctga tggggatcat tgctctcagt ggtgcgactc
     3241 atgacattgc gggggacgga gtatacctga ctgaactgac tgctacccag caagccaagt
     3301 atatcggttg gcagggagct ttttataatc tggccaagat acttgccaac ggaggcttgg
     3361 tttggctggc aggtatgctg aaggatgaat ttggagtggt acatgcctgg atgattgtca
     3421 tgttgatgtg tgcgggtatt atgattctga tcggtcttta ccacatccgg attttgcctt
     3481 cgggaggagg agcttccggt gaagtgaata cgatgagtga cgcattgaat atgctttggg
     3541 aagtcatccg ctcttttttc caaaaaaaac atattgcttt ctacattgtc tttatcattt
     3601 tgtaccggtt tgccgaagga tatgccatca agattgtacc gttgttcctg aaagcgtcgg
     3661 ttgcggatgg tggattggga ctcagcactc aggatatcgg actggtatat ggtacgttcg
     3721 gagcgggagc ttttattctc ggttcgcttt tggccggtta ttacatttcg gctttcggac
     3781 ttcggaagac tttgttttct ttatgttgcg cttttaatat tccgttcttg gtatatttcc
     3841 tgttagccct ttaccagcct tccgatctat ggattattgg tatggccatt gtgtctgaat
     3901 acttgggtta cgggtttggt tttgtcggat tgatgctctt tatgatgcag caagtggctc
     3961 ccggcaaaca tcagatggca cattatgctt ttgctaccgg tattatgaat ctgggggtga
     4021 tgcttcccgg aatgatgagc ggatacctga gcgattggct gggttatcgc gatttcttta
     4081 tctgggtact tatcgctacc ataccggctt ttatcgtgac ttggctggta cctttcacat
     4141 atccggacgg aaagaagaaa taaaaagaga ttttcaatat aaacaagata tatacataat
     4201 attaatttaa tcgaatcatg gaagaaatta aaattgcagg tgctgctttg ccggctatgc
     4261 cttgggaaga acgtccggca ggatgtaaag atgtagtgtg gcgttgttcg gccaatccga
     4321 ttattccgcg cgacttgctc cctacttcaa acagtatatt caacagtgcc gtagttccgt
     4381 ttaaggatgg ctatgcaggg gtgttccgtt gtgatgatac taatcgtcgc atgcgtttgc
     4441 atgtgggatt cagcaaggat gctgttcatt gggatatcaa cgaagaaccg ttaaagtttc
     4501 aatgtgatga cgctgaggtt ggaacctggg tctatggata tgacccacgg gtttgcttta
     4561 tcgaagaccg ctactatgtg acctggtgta atggctatca tggtcctact atcggtgtgg
     4621 cctacaccta tgattttgtt acttttcacc agttggagaa tgcctttatt cctttcaatc
     4681 ggaatggagt cttgttccct cgtaagataa acggtcgttt tgcgatgttg agccgcccga
     4741 gtgataatgg gcatactcct tttggagata ttttctatag cgagtctccc gatatggagt
     4801 tctggggacg tcatcgtcat gttatgtcgc cggctccgtt cgaagacagt gcctggcagt
     4861 gtaccaagat cggtgcaggg cctatcccga ttgaaacctc ggaaggctgg ttactgatct
     4921 atcatggtgt attggcttcc tgcaacggtt ttgtgtatag ttttggttcg gcactgcttg
     4981 acatcgatca gccctggaaa gtaaaattcc gttcggggcc ttatctgatt tcacctcaga
     5041 aggattacga atgtatgggt gatgtgccta atgtctgttt cccatgcgca gcgcttcatg
     5101 attcggagac cggacggatt gccatctatt atgggtgtgc ggatacagtg accgggctcg
     5161 cattcggata cattccggaa attattgaat ttaccaaacg tacaagtatc atctgaatcg
     5221 aataaaacag aaagggtgta gctatcccgc cgggatggct acaccctttt gcttgtatgg
     5281 ctacaccttt tcggtcagat ggctacaccc tttcggctgt tatccgttgt atgcagtcag
     5341 catccaaacc atcttttcct gttctttcag gtagtcgctc atcatggcca ctgttacttc
     5401 gtcgttgtgt gaagaggcga gagacaggat tttacgttct tccgcaatca gatgcccgta
     5461 agtttcgaga atatgattca gagcgtcgtc ggccttattc actccgtcca cttccttgat
     5521 ctgcgccatc ttcagatagt cactgtattt attggcggga gttcctccca gcatcagtat
     5581 acgttcggct atttcgtcca ccttttcggc ggctccgtta tataaatctt caaacttgct
     5641 gtgcagtacg aagaaaccgt gtcctttgat gttccagtga aatcctctca ggtttgcata
     5701 atgaatctga aaatcggcaa gcagttgctg taatgacagt acgatggtgt tagctccttt
     5761 ttcttccaaa tgtgtataat ttaaagtctt cataatgata ttgttttttt tgagttaata
     5821 ctatatttct tctttttatc tggaacaaag atacggtaca aaatgattcg tgtcaaactg
     5881 aaaatttcta tctttgcatt gatagattct atatctttaa taaatcagag aacgatgact
     5941 atacaacaat tggaatatat tctggctgtg gaccagttcc ggcattttgc taaagctgcc
     6001 gagtattgcc gggtgacgca acctactttg agtgcaatga tccagaagct ggaagacgaa
     6061 ttgggggtga aactgttcga ccgtagcatg acaccggttt gccctactgc cattggtaag
     6121 aaagtgctgg aacaggcccg taagattctt tcggaagtta tctgtgtcaa ggagatcatc
     6181 agcgaagaac agcactccct gtcgggtaca ttccgattgg cagtgttacc gacgattgca
     6241 ccttatcttc tgccccgttt ctttccgcaa ctgatggaga aatacccgga tcttgatata
     6301 cgggtgatgg agatgaagac gcccgacatt cgcaaggctc tgctgaccgg tgaagcggat
     6361 gctgctatca ttgccagcat gctggatgat gccgcattaa cggaagagac cttattttac
     6421 gagcaattcc tgggctatgt ctcaaagaag gaaccgttgt tcaagcacga tgtgattcgt
     6481 acgtccgatg tgacagggga acggctttgg cttcttgacg aagggcattg cttccgcgat
     6541 cagttggttc gtttttgtca gatggaagcg gttaagatca gccaaatggc gtatcggctg
     6601 ggtagtatgg aaacctttat gcatatggtg gagagtggta aggggattac gtttattccc
     6661 gaactggcag tgatgcaatt gagcgaagag cagaaagaac tggtccgtcc gtttgctatc
     6721 ccgcggccta cccgtcagat tgtcctggtg acccggaaag acttcatccg caccagtctg
     6781 ctgcaggttt tgaaagagga gattcaggcg gcggttccca aggagatgct taccctgcag
     6841 gccgttcagt gtctggtata atataaaaac gacggcgata ttttcacaaa catcgccgcc
     6901 ttatttcttt tatgtatcag aattattact cgttttgcct gattgtgtag gtgtttcttg
     6961 ttgttttatt gagaatgaaa tgattttatt tttaagtttt tgtcttcgtt gatatctatt
     7021 gtgacatact gtatattgtc ataaatggtg ttcacacgga gttttattcc tttggctgtc
     7081 gccaattgct cggctatact atccagcttg aaagaaacaa ggctcgaacc caattgattg
     7141 ggggagtcat taaaggcatt atgccggaac tccagataga tatatccgtc atcttttatg
     7201 ggacctgtta tttcgttttg taccaagttc agcatgtgtt ttttattttc attcatgctg
     7261 cccagatatt gatattcgat ggtcagataa tctttcgtaa gtgcatgcgc tgtgacgttg
     7321 atacggtcgt ctccaatgct gtctgctgta gcttccgtca gtggaatgat ctctttcgtc
     7381 aatatatctt ctatcgtgaa tattttaccg ttctcatatc cgggtttctc ttctcccatc
     7441 tgcagatagc caacgaagac tctttgacct tctgcaacag tgtatttcct gttgcgtata
     7501 tcggccgtat ctgccggaag tacattgtct ccattgtcca acgcaatgaa aaagtccctt
     7561 ggagtgtccg cattgggaat cttcattgtg ccgatggcta atattccacc cggaggacaa
     7621 gtgacccact cgtcgttgtt ggcatcgtcc agacatgact gtaaaatggg caataacatc
     7681 aggatgacgg caaaagttat taaattaaat ttcttcataa gtttcttgtt ggttttatcc
     7741 tatttatcca ttgagattta ttctttattg tattgagaaa atgcaggaag tgatgaaata
     7801 ttgcatccta aaatgttaaa gaaacaaaag tgataaaaga gttgttctct ctgtgcagta
     7861 tttctatctt tgctgcattt ataaggtaaa cacgtgttta ggagaatgaa tgaattagag
     7921 ctgtcggaac gttgcaggca gggagataat cgtgcccgca aagaacttta tgagcagtac
     7981 gcagggcgca tgcttggtgt ctgtcttcgt tatgccggag acagggacat ggcacaagac
     8041 ttggtacacg acggtttcct gaagattttc gactccttcg acaagtttac ctggcggggt
     8101 gaaggctctc tgagagcatg gatggagcgt gtaatggtga atacggcttt acagttctta
     8161 agaaagaacg acgtgatgaa ccagaccacg gcactggatg aagttcccga aacgtatgaa
     8221 gaaccggatg cttcggctgt tgaagcaata ccacagaaag tgctgatgca atttattaat
     8281 gaactccccg ccggatatcg taccgtattc aatttataca cctttgaaga taagtcgcac
     8341 aaggaaatcg cacagatgtt ggggattaat gaaaaatctt ctgcctcaca gctttttcgc
     8401 gcaaaaagtg tattggcaaa gaaagtgaaa gaatggttgg tgaccaatgg ttgacatgta
     8461 tttacagata ctgaggtgaa ccttggattt caaaaatgaa atagaatgat gaaagaagac
     8521 gaaaaatgga ttaaagcatt caaggataag ctcgaagatt attcggagcc gatgcctact
     8581 tccggttggg aacgactgga aagggaactg atgcctgtaa ccgaaaaacg aatatatccg
     8641 tatcgccggt gggcggttgc tgcggcagct gtggtattgg tggtaacgac tgctgtcagt
     8701 ttgtattttc tgaatagtcc ggtagctgat gaaatccgtt atgcaacggc tccttcactg
     8761 gctgtcaacc cggatgtatt gccggaacct gccttgccgg atgtacaggt agctgtatcc
     8821 gaacccgtta agccggtagg aacgacgagt atcaaccctg tttcgggcta tttggcaaaa
     8881 aatactgatc cggtgattgt tccggaggta tcctccctgg cagagaagcg accggaggca
     8941 gtgacggagg aaaagagagc tgagccgcaa caggaagcaa ctgctgcaat cgagaaaaaa
     9001 gaaagtgcga cggcgcagcc tccaaagagg aaagaagcgc ggcgaccgtc cggtaaagac
     9061 aagtatcagt tgcctatcgg agactcttct gctaaacgtg gtggtaaatg gtcgatggga
     9121 gtgggtatcg gtaatggagg tggacttccg acaaatggtt ccgaaatttt tgcgccccgt
     9181 ccgatgacta acagggtcga cttgatgacg atcatgaatg gagctgtgag tattcctgcc
     9241 gatcaggaag ttatatttga agaaggagtc ccttacctga agtccaatac aactgccgtg
     9301 gtggattatg aacatcatca gccggttagc ttcggactgt ctgtacgtaa gtctcttccc
     9361 aaaggtttct ctgtagagac gggattgact tatacgttgt tgtcttctga catcaaacgg
     9421 cagggggata ccaagatgca gagtcagaaa ttgcattata taggtattcc tgtacgtgga
     9481 aactggaatt ttctggaaaa gaaatatttt acactctatg tatctgccgg aggaatggtt
     9541 gaaaagtgtg tttatggaaa gttggcggat gataaggtga atgtgaagcc tttgcaattt
     9601 tctgtagccg gtgccgtggg agcgcagttc aatgcgacag atcatgttgg cctatatgtg
     9661 gaaccgggag tttcgtattt ctttgatgat gcctccaaag tacaaaccat ccgaaaagaa
     9721 aggccttgta actttaattt gcaggcagga ttgcgattca cttattaaag tagggtggca
     9781 aaaaatatgc cggttacatt atttccctgt tcttgccttg tattgtaatg aattgaggca
     9841 agaacaggga gatttttatg tcgtgactta caaaattata aataagcgca atcgtcataa
     9901 ttcaccgcag agtgaactta atctattgat ggccaatgaa tctttatctg tgtaaattcg
     9961 tgtaatctgt ggcgaatacg agtttcgaca cttatataag tcaattcact tgtacggtcc
    10021 ggaaatattg cctgaatagt ttctcagcct tttctatctg ctccggagta ttctctttca
    10081 ctcctttcag catatattct ttgttcattg cttcatattt gtgaacaccc aaggtgtggt
    10141 aaggcaatat ttctacacgc tgaatcatct ggtacgttcc aagatgctct cccagctgcc
    10201 ggatatcgtc ttcgaagtca ctgtagccgg gcactaatac gtatcgcaac cagaatggtt
    10261 tatgattggt ttcaagccag gctgcggttt tcagggtctg ctcgttgctt cttccggtta
    10321 aagactgatg atgttccgga ttaaattctt tgatatctaa taaaaccaga tcagtcaatt
    10381 ccaatagttc ctctacatca ttgttccata gcccgccatt ggtatcaagg caaatatgga
    10441 ttcctgcttc ctttagtctt ttaaaaagtg ggataagcga ttttgcttga aaagtaggct
    10501 ctccgccgga aaaggtgata cctccctttt taccgaagaa agctttctga ctgacggcca
    10561 tgcgaactat ttcctcaggg tcggttgctg tccctccttt ggcttcaatt gtgtccggat
    10621 tggcacaata gaggcaacgg aagttacacc cttgaaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccatt gactcgtatg agtgtacgtt tatcattcaa ttacattctt
    10741 tcgtggaaac tgcggctgat tacttccaac tgatgttcgc ggctcaattt cacgaaatta
    10801 acggcatatc ctgagacacg gatagtcagt tgcggatact tttcgggatg ttccatcgca
    10861 tcctgcaaca tttcccggtt cagcacgttt acgttcaggt ggtgtgcgcc ttttgtaaaa
    10921 tatccgtcca tcatggtcac cagattgtcg atacggtctt cttgtgttgc tcccaatgat
    10981 ttgggaacga tcgagaatgt attgctgata ccatcctgtg agtcgcgata acgcaacttg
    11041 gctacagaac tcagtgaggc gattgcacca tttttatcac gtccgtgcat ggggttggca
    11101 ccgggagcaa aggcaatgcc tttggcgcgt ccgtcaggag tggcaccggt cttcttgcca
    11161 tacattacgt tcgaagtgat agtcagcagc gagagggtag gacgggcatt cttatatacg
    11221 gggagtttct ttaattcttc gctaaagaaa tataccaggt ccacacccag gtggtctaca
    11281 cggtcatcgt cattaccgaa acaagggaaa gcaccttcga tatcgaatcc ctccgtcagt
    11341 ccgatgtcgt tgcgacgggc tttcacatgt gcatatttga tggcggacag tgaatcgatg
    11401 gcgattgaaa gtccggctac accataagcg aggttaatgc ggggatcagt atccacgaaa
    11461 gccatctgcg ccttttcgta gtaatactta tcgtgcatgt aatgtatgat attcattgct
    11521 tcgttgtata cacgtgcaat ttgtatcaat actttcttat agttggccat tacttcttcg
    11581 aacttcagtg tttcaccggt caatacaggg atgtctttta ccataactgt acctgtattt
    11641 tcgcaacgtc ctccgttgat agccagtagc agggctttgg caaggttggc acgtgcgccg
    11701 aagaactgaa tctgctttcc gatttcctga tatgaaacac aacaagcgat tccgtagtca
    11761 tccgattgac ggacttcacg catcaggtcg tcgttttcgt attgtacgga agaagtgtcg
    11821 atagatactt gtgcacagaa tgctttgaaa ccttcgggta attcagggct ccatagtaca
    11881 gtcatgttag gttccggtga cgggcctaag ttataaagtg tctgcaagaa gcggaaagaa
    11941 gttttagtaa ctttggtacg tccgtcattg aaacgtccac cgatagattc ggtcacccat
    12001 gtgggatcac ccgcaaaaat atcgttgtac gactgcatac gcaagtggcg taccatacgg
    12061 agtttgataa cgaattggtc gatcagttcc tgagcgaatg tttcggttat cgtaccctgg
    12121 cttaattcat attcaagata gatgtcgagg aatgaagata cattacccag tgacatggca
    12181 gcaccatcct gctcttttac ggcagccaga taagccatat acacccattg tacagcttcc
    12241 tgtgcggtat atgccggtcg gctcagatcc aaaccataat attcgcccaa tactttaatc
    12301 tctttcaggg ccttgatttg ctcggctact tcttcgcgaa gacgaatgcg ggcttcagtc
    12361 ataggacctg tcagattatg cagatcttct tttttagctt ctatcagacg gtcaagacca
    12421 tagagagcca ggcggcgata atcaccgatg atacgtccgc gtgcatagtt gtcgggaagt
    12481 ccggtaagga atcccaatga acggaacgaa cgaatttctt cggtatacac atcgaatacc
    12541 ccatcattat gagtcttgcg atagtgagtg aagatatcct taactctgtc atctacttcc
    12601 actccgtttt cacggcaagc tttcataacc acattgattc cgccaaacgg tttgatggca
    12661 cgttttaaca cctgatcggt ctgtagtccg acgatcagtt cgttttcttt atcgatgtag
    12721 ccggcagggt gagaggttat agtagataca gttgtgtagt cgagtgcacg aataccatta
    12781 ttgtttctct cttcttcgag agctttgaga cagtgattcc agacagcttt ggtgcgttcg
    12841 gtaggtcctt gcaggaaaga agcatcccct tcataaggag tgatgttgtt actaacgaaa
    12901 tcccttacat tgatttcttt gctccaaagt ccatctttaa aggtcttatt cagttccata
    12961 aaattaatca gttagtggtt agttatcctt tagagcgcgc aaatttacaa ccttttttcg
    13021 gtttaggtat ataaaagggt cctattttat gttgaatagc ataaaaatac ctatttatgg
    13081 ggagaagcta gatagcagtt attacttcca aatatacttt tctaatattt ttttgcggaa
    13141 taatttgcaa gttaaaaaat gattcgtacc tttgcagcgc tttaagagaa aagcactact
    13201 taaccgtagt tctggagagg tggcagagtg gtcgattgcg gcggtcttga aaaccgttgt
    13261 actgcgaggt acccggggtt cgaatccctg tctctccgca ataaatactg aaaatcagtg
    13321 atttgcaaga ataacaccca attttacacc ctaaaaagta aaattgggtg ttttgtatta
    13381 tttaagattt gtttcttgct gttccatatt taattattcc aactgggggc tattctaaat
    13441 ttcctgctta tgcagtgtgt ctatagaagg ataatgatta tatatttttt gttttgattg
    13501 aatctgtttc tacaaatgta gaatgtgagg gttatgaatg ctacttcctt tctaatccaa
    13561 taaattatag tttttataaa ctattattcg cattggtaaa attgtataat tagattaaaa
    13621 ttttgtattc aaccgtttgg ctgtaacaaa aacaaagtac atttgccata taagtaatat
    13681 tttgaaagag tttaaactct taagtgaata attagccatg gaattactga attttatatc
    13741 acctaatacc ttatcattgt tgacaactta ttattgtacg gcagcgtgta agaattgttg
    13801 ttttgagtgt aaccaagaac gtagggggag aatgtcattt aaacaaatgg aaacctatat
    13861 atcggaatgt gtaaaagctt tccctacgat taggctggtt gtctttagtg gtggagaatg
    13921 tttttcctta aaagatgatt tatatcaagc tatttattat gcacataaaa aggggcttat
    13981 aacaagggtt gttactaatg ggtattgggc tgttagttat gaaaaggctc ttggaatttt
    14041 ggtgttacta aaggagttgg gattaaatga attaaattta agcacggggg atgatcatca
    14101 aaaatgggtg ccctttgata atatcgtaaa tgctataaga gcagcagcta aagtggattt
    14161 gccttgtttg gtgaatatag aaacgaatcc aagttcacag ttttctgagg aagatttcaa
    14221 aaatcatgaa gagttaaaag agtatatacg ggataataaa gttatctttt cttctggtat
    14281 atggattcca tttgatatgg aggataaaat taaacgtgat acaaattata atgaattaat
    14341 aaaacataga tatgtgcaga gacctataat atcccatggg tgcaacagtc tatttgagag
    14401 tattcctatt gatccggaag ggaatgtgta tgcttgttgt ggactggctt gtagaaaagc
    14461 taagttttta aaaattggca atatgaatac tgccggtata aataaaatat atagaagaca
    14521 atttgatgat tttttaaaag tatgggctta tgttgatggc ccgaaattta ttttgaataa
    14581 aatagcaatg gaaaccggga aaaatgttga ggttaatgct gatatgcata attgtgaagc
    14641 ctgtctatta ctgttgaatg atccctctaa aatagagtat attaaaaata atatatccag
    14701 atatatatct gaggttgtat taaaatataa tattaaacaa aagaaagcga actatgaaaa
    14761 gtaaaattct aactttaggt gttggggcag cgatagctgc tacttcattt tcttcatgtg
    14821 ataattcaaa tgattttcct aatttagcca ttgcgtcaga agaaaatctt gtagatgatg
    14881 aaactactgc tatttctatg aaaaagttat cacaggagga acaggtgtat attcacgata
    14941 tgagtttatt atcacataat attttaaatg atacaaatgc agcggaagct tttttgaatg
    15001 cccctttgga atatgcccgg tctttgggaa taaaaagctc tatagatact gatgacggta
    15061 ctgtacgttt tttattagca atttgtaagc cggaatttcg agaggctgta ataaagagag
    15121 atattagaag atttgtagag ttatgtgaaa agtatgatat ttttaaaaat gccaattctt
    15181 ccaatattaa attattgaac catactgcaa taacaagaag taaagactgt gtagatgtgc
    15241 aaatgggatt cttttggatc ggtgaatgga ttttgttagg tgttgcatat gttggggcag
    15301 gaattgatta tgcagcactt ggtggtcccg tagtatgtgc ttccagaaca attaacagtg
    15361 aaatggcatt gcaggtttgg gacgttgaaa cacaggacgg aagtgtatat gagttagcag
    15421 atgagtacaa aaatcactat gttcaagatt tggttaagtt agtaaaagaa aaacgtcctg
    15481 aggttatgga acgatatacg gataaagaac ttattgaaat aatacagaag acattagcaa
    15541 tataatgagc gtatataaat caaaatttca gccggtaatg gagcgttggt ctctggtatt
    15601 aaagatggtc ttattaacta ctggccttat gtttctatta agaactttta tgctacaatc
    15661 tttgcaggat caaatcgca
//
