LOCUS       gnlProkkaPNALKBAD_26   10661 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNALKBAD_26.
ACCESSION   gnlProkkaPNALKBAD_26
VERSION     gnlProkkaPNALKBAD_26
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:40:33
            Original ID  :: gnl|Prokka|PNALKBAD_26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10661
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10661
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1347:5661]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1348..5661
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10661
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10661
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..125
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="MIIVPSKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             136..1284
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             1348..2067
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.4e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2088..3389
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.1e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             3406..4530
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.2e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4540..5661
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg26_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4630..5637
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg26_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg26_6_Aminotran_5.1"
                     /locus_tag="ctg26_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5658..6131
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 73.7;
                     E-value: 2.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAVLYPYKKAPVVI
                     GDNVWIGANVTILPGVTIGDYVVVAAGAVVTKDVPSGVLVAGVPAIVKKRFNK"
     CDS             6128..7573
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="Polysacc_synt (E-value: 9e-33, bitscore:
                     103.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKTSLKNKAICGIFWSAVERFLSQGIQFVVTVIMARFLLPSDY
                     GMVGMLAIVLQLSQTLMDSGFTNALIRYKERTEIDYSTVFFFNILASLVIYFLIFFLAP
                     YISWFYKIGQLVEITRILSIVIVLNSFAIIPKTKLIIAVDFKTQSKVSFIAALVSGIIG
                     IWAAYLDFGVWALVGQTLVNGLLIVVLYAYFCRWKPLWIFSLKSFRLLFAFGSKLVLAN
                     ILNTLYKNLYAIVIGKKFSSVDLGFYTRAEQFAQFPSYNLSAIISRVTYPILSLVQNDN
                     DRLSALYRKYVRLSSAFIFPLMILLIVIAQPLVLLLLTEKWIGVVVLLQILCLDWMFDH
                     LSSINLNLLYVKGRSDLALRLEVIKKVLATGILLLSIPWGIVGMCWGRVMYSLIAVYLN
                     TYYTESLIKLSLIRQMRDILPSFFLALIMGGGTWYMILLLEGEIVQIVVGSVIALLLYG
                     TLLYCFSRSLFDEIWAVILKIKR"
     CDS             7573..8295
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MDKLSLIISKIRRNHWYRTYMRPIYLFVYGNRKLKNRNRIFLQYS
                     QELLTNFHQAMNEVGIPYWLEFGTLLGAVREHSFISHDFDLDVGLFKEDYSDIIREVLK
                     KYGFKRIRCITALDFIDAYEETYLYKGVTIDLFLFSREKNCDGVYCYDFVPVYSDIKRT
                     KKGDNAIRRIHFPRIDLIEYSFIGINTFVPENYEEHLCMHYGKDYMIPNPHWKDSDAQH
                     TDIFYGREIRIELFDKSK"
     CDS             8309..9322
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MFYLFFLLIVLFLLYIQSRKRQYSTVAGICVPIIIIFVVICRYRV
                     GYDYLTYYTLIENEEEAQILYLFSPLSIVWAEIALYFESPQMLFVLFGLPTFALLIFTL
                     KKYSKDYALSVTILICFFFFTSLSIIRQALALAICFYGYRFIVKRSLIKYILCILIAAL
                     FHPSAGVAIIIYWLPFLKFRLVVLLSIISIVAKPLFFYMLNILGVYTSYLDGKMDIEGG
                     KYTQLIYFLLFIICFVLGSKNIDKNKCNLFNVLLLSFVFVSFLGAHLGGRIAFYFNIYY
                     CLLIPKVVKGLDGQLREQVKLLSYFLCISYFLLYLFVPFIKGVPSYYIPYKFIFFK"
     CDS             9327..10286
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 57.2; E-value: 3.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-42,
                     bitscore: 135.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLISIIVPCYNSERYLSDCLLSILNQTYVNWEVICIDDGSQDNTL
                     SILNHYATLDERFKIISQSNAGVSVARNKALSQCQGEYICFVDSDDLIEPNFLITLLQL
                     ISHQADLAICGFTRSMVFCMDDAQGYIEMSGKRCIERIILDKSFNPQICCMLFRHNIIK
                     EKQLEFVIGCTRGEDREFILKYLVYSNKVCYTNNLLYHYRVNDQSAMAIFSIKSLTSIE
                     ASQRTVNYYKKVNYSVRGLEFEFSRTLWKFMILAILSGQNDLYQIIREKYDLKRQMEHL
                     YSHPGLSEKLTARLFVWNEALFKWVFSIIRYLYKKRWR"
ORIGIN
        1 gtgagattat tgtgcctagt aaggctaaga agaaagggaa catagctaat attttaggtt
       61 atgctacttc cttcagttct ttgggaatga tgattgcttc tattgctaat ttgataaaga
      121 aataaatgac ctattatgat tgaaaagcaa tcttatcaag aaccgttttc tgaagtggat
      181 aaaaggaaag atgatgaaat ggaaatagac ttgatggcta ttttttataa gattattact
      241 gttcgtggag tactatgcaa agctgctgga gtgggagtaa taattgctat agtggtggca
      301 ttgagcattc ccaagcaata tacagtaaag gttacccttt ctcctgaaat gggtaatgcg
      361 aagggaagta atggtttagc cggacttgct gcctcgtttt tgggagatgg ggctctaata
      421 ggggaaagca cagatgcctt gaacgcttct ctttcagcag atattgtttc ttcaactcct
      481 tttttattgg aacttttaga aatggaagtc tccgtttcta aaaaggatga taaaatgact
      541 ttggggtctt atctcgatga agagtcatct ccttggtggg attatcttat aggttttccg
      601 ggcatagtaa taggaggagt taaatcatta ttcggagaag atacggttcc tgccagtgga
      661 gggcggcaag gaactatcga attgacgaaa gaagtaaatg agaagattaa ttttcttaaa
      721 aagaagatta gtgcatccat tgataagaaa accgccataa cgagcattac ggtcacctta
      781 caaaatccgc agatcactgc ggttatagca gattctgtcg ttcataaatt acaggaatat
      841 attattgggt atcgaacttc aaaagtaaaa gaagactgtg cgtatttgga acggttgttt
      901 aaagaacgtc agcaggaata ttatgctgct caaagaaaat atgcggatta tgtagacgcc
      961 catgataatg tggttcttca aagtgtacgt gctgagcagg agcgtttaca gaacgacatg
     1021 agtttggctt atcagatata tagtcaggtt gctaatcagt tgcaggtatc cagagccaaa
     1081 gtacaggagg aaaagccagt ctttgcagta gttgagcctg ccgttgtacc tttgaaacct
     1141 tcaggtatgg gactcaaaat ttatatttta ttatttgtgt tcctgtccgt atctggtact
     1201 ctcgtgtggg tgctttttgg caaaagtctg ctggctagct tgagaaaaga actgaaaaat
     1261 aaggagatag aacaggataa atgatgctaa aacgtcgttt acaacattct tacatcaatt
     1321 aaattcactt actatattat taaacgaatg atacgtacag ctatgataat ggctgcgggc
     1381 atgggaaccc gttttggcca atatacagaa ttgataccta aagggttcgt caaagtggga
     1441 ggtattccaa tgatagttcg ttctattgat actttgttat catgtggcat tgagcgaatt
     1501 gtaatcggta caggatataa acaagaagtt tatgaagaat tgaagacaga ctatcctatg
     1561 cttgaaacct gttttagtcc tcgttatgct gaaacaaata gtatgtatac tttatataat
     1621 acgcgggaga ttctgggcaa tgatgatttt ttattgttag agtcagattt gatttttgag
     1681 aaacaagcaa taatgagctt attggagtgt cctgcggcag atgcaatgct aataactcca
     1741 gtgacaaagt ttcaagatca gtattatgtg gaacatgatg ataattttcg cctttcttca
     1801 tgttctgtca ataagaataa actaaacgct aaaggcgaat tggtcggcat ccataaacta
     1861 tccggttcct tttacaaaat aatgtgtgct gattatgcga gtattgttga tgaacaaccc
     1921 aatttgggat atgagtatga attactacga atatcttgtt ctcaatctcc tgtttatgtg
     1981 cataaagtag aagggctgaa atggtatgaa atcgatgaca tatcagattt ggaatatgca
     2041 gagaaatata ttgttccgta ttgttaatta aaataatata tcaaattatg agtaagacag
     2101 tttatattgg gatgactgcg gatattatgc atccaggact tatccgcatt attaatgagg
     2161 ctactaaata cggtgatgtt ataattggtc ttcttacaga taaagctatt gcggagcata
     2221 aacgccttcc ttatctgacc tatgaacaac gaaaagaggt agttcagaat attaaaggcg
     2281 tatgtaaagt tgttcctcaa gaagaatgga gctatgttga gaatctcaaa cgcattaaac
     2341 ctgactatat aattcatggt gacgactgga aaaccgggcc tttacgtgaa gaacgtgtgc
     2401 gcgtatttga agtgatgaat gaacagggag gaaaggttat cgaaattcca tatactttgg
     2461 gaattaattc atcttctttg gataaagata ttaaggctat aggtacaacc cctgatgtac
     2521 gtttaaaatc acttcgtcgt ttgataaatg ccaaacccgt agttcgtatt ttggaagctc
     2581 atgatggact atgtggcttg ataattgaaa atcaggaaat attaaaaggg gataagaggg
     2641 aagtatttga cggaatgtgg tctagtagcc ttacggattc aaccagtaaa ggtaaacctg
     2701 atattgaggc ggttgattta actacccgat tgcaagattt gaataatatt ctggagtgta
     2761 ctactaaacc tattattttt gatggagata caggtggtaa aattgaacat ttcgtattta
     2821 cagtacgcac tttagaacgt catggaattt cagctataat aattgaagat aaagttggat
     2881 taaaaaagaa ttcattgttt ggtacagatg ttattcaaac tcaagataca atcgaaggtt
     2941 tctgtaataa gatcaaagca ggaaaggcat ctcagattac tgatgatttt atgattatcg
     3001 ctcgtattga gagccttata gcgggaaagc cggtaagtga tgctttagag agagcttttg
     3061 catatgtcca agcgggagcg gacggtatta tgatacatag caaaaataag tcgggtgaag
     3121 atataaaaga attttgtttg gcgtttcgaa aacagtatgc tcatgtacct atcgtggttg
     3181 tgcctactac atatgatcat atttatgagt ctgaattgtg tgattggggt gtgaatataa
     3241 ttatttatgc taatcatatg cttcgtgccg cttatcctgc tatgatgaat gtcgcaaaga
     3301 caatattaga gaatgaacgt gctttagagg tgcgcgaact gtgtatgccc ataaaagaaa
     3361 tattggaact gattccaggt actaaataaa aagaggaata tcattatgtt aagcgtagaa
     3421 aaagtttatg aaacgtttct gagtcatgac gttgattttt ttacaggagt tccagactca
     3481 ttactaaaaa atatttgtgc ctatatcaca gaccatactt cacgtgagaa acatatcata
     3541 gctgctaatg aaggtgcggc tgtaggaatt gcttcaggtt attatatggc atcaggtaag
     3601 gttcctgtgg tttatatgca aaattccggc ttgggtaata ctgttaatcc tctgctgtct
     3661 cttgcagatg aacaagtata cagttttcca atgcttttga tgattggctg gcgtggtgaa
     3721 ccgggaacaa aagatgaacc tcagcataaa aaacagggtg aggtaacttt agatttgttg
     3781 aaagcaatgc ggattcctta tataattctt gattcaaatg agaatgatgc atttattcag
     3841 ctccatgata tcatacaatc agcaaaaact aagaatattc ctcatgcaat aattattcgg
     3901 aaagatgttt ttggcaaata taaacttcaa aaagagtttg gatgtaatta tcctttatct
     3961 cgtgaggatg ctttgcaaat agttgtggat tatctgcctg aaaattcagt ggtcgtttct
     4021 actactggca agctttctcg tgagttattt gaatatcgag aaatgaaaga gcaaggtcat
     4081 gaacatgatt ttctcacggt aggctctatg ggacatagtt catcaatctc tttgggtatt
     4141 gctatagcaa agcaagatag acctgtttat tgcttggatg gtgatggagc atttattatg
     4201 catttagggg caattagtaa cattggcgat ttatctccta aaaactatta tcatattttg
     4261 tttaacaatg gtgctcacga gtctgtagga ggacagccta ctttaggatt tagtttagat
     4321 attccggcta ttgtccgggg gagcggatat aagcatactt atactgtttg tacaaaagtt
     4381 gaaattgaag aagcaatgaa gcagcttcca aagttatgtg gtcctgtttt gttggaaata
     4441 aaggttaaaa tagattctcg ggagaatttg ggacgtccca cgactactcc tatagagaat
     4501 aaggagcatt ttatggattt tttaaaataa atatattcga tgaaaataga aagaaaaata
     4561 ttattaaatc ctgggcctgc cactactact gacagtgtaa aaatggcaca agttgttccg
     4621 gatatttgtc ctcgcgagaa agaattcgca ggtatgatga aacaacttcg ggacgatttg
     4681 gtcagagttg ctcatgggaa tttggaaaaa cataccgctg tattattttg tggctcagga
     4741 accatcaata ttgatatatg tctaaattct cttcttcctg aagacaaaag ggtgcttata
     4801 gtgaataatg gggcatatag tacccgtgct gtagaagtgt gtcaatatta tggtttgcct
     4861 catattaatt tggaattttc cgtttatgaa cgtcctgatt tatcggtggt ggaaaatgtg
     4921 ttgcaagaaa atcctgatat agctatggtt tatactactc atcacgagac gggtacagga
     4981 attctgaacc ctattcgcga gatgggcgct atagctcata aatatcaggc taaatttgtc
     5041 gtcgatacta cttcttcttt gggcatgatt ccttttgata tagagaaaga taatgtggat
     5101 ttttgtatgg catctgctca aaaaggactt caagcgatga caggtctttc ttttattata
     5161 ggcaatgagg aacagattaa gttttcaaaa aaatatccca agcgttctta ctattgtaat
     5221 ctttatttgc agtatgagaa ttttgagaga acaggtgaaa tgcattttac tccaccggta
     5281 caaactattt acgccactcg tcaggcatta aatgaatatt ttgaagtggg cgaagaagct
     5341 aagtttgccc gtcacaaaag agtttttgag gctattcatt caggtataaa tgaaattggt
     5401 cttaaaagtg taataaagcg tgaatggcag tcaggactgg ttgtctcagt tcaataccca
     5461 gaagatccca actgggattt tgagaaaata catgattatt gttatgagcg tggatttacg
     5521 atttatccag gtaagatatc aactgaggat acttttagaa tctgtgcttt aggagagata
     5581 gaagtagatg atattgagaa cttctttaaa gtactaaaag ctgcattaaa tcattataac
     5641 gtcacattac cgatgtcatg attgcagaaa tattattgaa gattcgtcat ttttattttt
     5701 cccttcgtgg tatacacttc catccggaaa gtgttatttc tggagtgcct attcgtagct
     5761 ttcgcttagt aggcaaatat agcaatatct acttaggtaa aaatgctgaa atacgttcag
     5821 gctgttatct gattgctcgt gataaaatca ttattggaga aaactcaaca ctcgcctatg
     5881 gaacgactat attgacaact gctgatccta atggaccgta taatgcatta gcagttcttt
     5941 atccttataa aaaggcaccg gtagttatag gagataatgt ttggattggg gctaatgtta
     6001 ccatccttcc tggagtaact attggtgatt acgttgtagt agcagctgga gctgttgtaa
     6061 caaaagatgt accttcagga gtattggtag ctggtgtacc agctattgtg aaaaaacgtt
     6121 ttaataaatg aaagaaaaaa cttctttaaa gaacaaagcc atatgtggaa tcttttggag
     6181 tgcagttgaa cgatttttat cacaggggat acagtttgta gttacagtca ttatggcgcg
     6241 ttttctattg ccatctgatt atggaatggt aggaatgtta gcaatagttc ttcaattatc
     6301 tcaaacgtta atggatagtg gttttactaa tgcccttatt cgttataagg aacgtactga
     6361 aattgattat tcaacagttt tcttttttaa tatattagca tcattagtta tttattttct
     6421 aatttttttt ctagctcctt atatatcgtg gttttataaa ataggtcaat tagttgagat
     6481 tactagaatt ttatctattg ttattgtttt aaattccttt gcgattattc ctaaaactaa
     6541 attaataata gctgtagatt ttaaaactca atcaaaagtc tcatttattg cagctttggt
     6601 ttcaggtatt attggcattt gggctgcata tttagatttt ggagtttggg ctttagttgg
     6661 acaaacttta gtaaacggat tgttgattgt agttttgtat gcatattttt gtagatggaa
     6721 accattgtgg atattttcat tgaaatcgtt tcgtttatta tttgcttttg ggtcaaaatt
     6781 agtattagct aatattctta atactttata taaaaatctg tatgctatag ttataggaaa
     6841 gaagttttcg tcggttgatt taggatttta tactcgtgcg gaacaatttg ctcagtttcc
     6901 ttcatataat ttgagtgcaa taatttctag agtgacatac cccatattga gccttgtgca
     6961 aaatgataat gatagattat ctgctttata taggaaatat gtccgtttat cttctgcttt
     7021 tatctttcca ttgatgattt tgttaattgt catagctcag ccactggtat tattgctttt
     7081 gacagaaaaa tggataggag tagttgtatt gcttcaaata ttgtgtttag attggatgtt
     7141 tgatcatttg agtagtataa atttgaattt actatatgta aagggacgtt cagacttggc
     7201 tttacgttta gaagttataa aaaaagtgtt agcgacgggg atccttcttc tatctattcc
     7261 ttgggggatt gtaggtatgt gttgggggcg tgttatgtat tcattgattg ctgtgtattt
     7321 gaatacttat tatacagaat cattgattaa attaagtctt attagacaga tgagagatat
     7381 actaccaagc ttttttttag cattaataat gggaggaggt acttggtata tgattttatt
     7441 gttagagggt gaaattgttc aaattgtagt aggaagtgtt attgctttat tgctatatgg
     7501 aacgttgttg tattgctttt ctcgatcctt gtttgatgaa atatgggcgg ttatattaaa
     7561 aataaaaagg taatggataa actgagtttg attattagta aaatacgacg gaatcattgg
     7621 tatagaacct atatgcgtcc tatatattta tttgtttatg gcaatagaaa attgaagaat
     7681 agaaatagaa tatttttgca gtattcacaa gagctgctaa ctaactttca tcaagcaatg
     7741 aatgaagtgg gaattcctta ttggttagaa tttggaactc ttttaggtgc tgttagagaa
     7801 cacagtttta taagtcatga ttttgatctt gatgtgggcc tttttaagga agattattca
     7861 gatataataa gagaggtctt aaaaaaatat ggtttcaaaa gaataaggtg tataaccgcc
     7921 cttgatttta ttgatgctta tgaggaaact tatctttata aaggtgtgac aattgatctt
     7981 ttcctttttt caagagagaa aaattgtgat ggggtctatt gttatgattt tgttccagta
     8041 tattcagata taaagagaac taaaaaaggt gataatgcaa tccggagaat tcattttcct
     8101 agaattgatt tgattgaata ttcatttatt ggaattaata cttttgttcc tgaaaattat
     8161 gaggaacatc tttgtatgca ttatggtaaa gactatatga ttccaaatcc tcattggaaa
     8221 gattcagatg cgcaacatac tgatatcttt tatggtagag agattagaat tgaattgttt
     8281 gataaaagta aataatagta gataatacat gttctatcta ttttttttac taattgtgct
     8341 atttttgtta tatatacaaa gtaggaaaag acaatattct actgtagcgg gaatttgtgt
     8401 tcctattatt ataatttttg ttgtaatttg tcgttataga gtggggtatg actatttaac
     8461 gtattataca ttaattgaaa atgaagaaga ggcacagatt ttatacttat tttctccttt
     8521 aagcattgtt tgggcagaga ttgctttata ttttgaatct ccacagatgt tatttgttct
     8581 ttttgggctt ccaacatttg ctcttctaat atttacttta aaaaaatatt caaaagatta
     8641 tgcgttatca gtaactattt taatttgttt cttctttttt acatcactca gtattattcg
     8701 acaagctttg gctttggcta tttgttttta tggttatcgt tttatagtaa aacgttcact
     8761 aattaaatat atattatgta tattgattgc agctttattc catccttctg caggagtagc
     8821 gattattata tattggttgc catttctaaa gtttagatta gttgtattat tatctataat
     8881 atcaatagta gccaaacctt tattttttta tatgctaaat atattagggg tgtatacctc
     8941 ttatcttgat ggcaagatgg atattgaagg tgggaaatat actcaattaa tatacttttt
     9001 gttgtttatt atttgttttg ttttgggaag taaaaacata gataaaaaca agtgtaattt
     9061 atttaatgtt ttattgttaa gttttgtttt cgtatctttt ttaggagctc atttaggcgg
     9121 gagaatagcg ttttatttta atatatatta ttgtttgttg attcctaaag tggttaaagg
     9181 attggatggg caactaagag agcaagtgaa gcttctttct tattttctat gtatttctta
     9241 tttcttattg tacctattcg ttccattcat aaaaggtgta ccctcatatt atatcccata
     9301 taagtttata tttttcaaat agtaaaatgt tgatatctat aattgtccct tgttataatt
     9361 ctgaaagata tttgtctgat tgtttattgt ctatattgaa tcaaacctat gttaattggg
     9421 aggtgatttg tatagatgat ggaagtcaag ataatacatt atctatttta aatcattacg
     9481 ctacattgga tgagcgtttt aaaattattt ctcagtctaa tgcaggagtg tctgtcgcaa
     9541 gaaataaggc tctatcccag tgtcaaggag agtatatttg ctttgttgat agtgatgacc
     9601 tgatagaacc taattttttg ataacacttt tacagcttat aagtcatcag gctgatttgg
     9661 caatctgtgg ttttactcgt tctatggttt tctgtatgga tgatgctcaa ggatatatag
     9721 aaatgagtgg taaacgttgt atagaaagaa ttattctaga taaaagtttc aatcctcaga
     9781 tttgttgtat gttatttcga cataatatta taaaagagaa acaattagaa tttgtgatag
     9841 ggtgtactcg tggtgaagat cgtgaattta tattgaaata tttagtttat tctaataagg
     9901 tttgttatac aaacaatctt ctttatcact atcgtgtaaa tgatcagtca gccatggcaa
     9961 tcttttctat taaaagtttg acaagtatag aagcttcaca acgcacggtc aactactata
    10021 aaaaagtgaa ttattctgtt agagggcttg aatttgaatt ttcacgtaca ttgtggaaat
    10081 tcatgatttt agctattttg tctgggcaaa atgatttata tcaaatcatt cgagaaaagt
    10141 atgatctaaa aagacaaatg gaacatcttt attctcatcc aggactatcc gaaaaactta
    10201 cagcgagatt gtttgtttgg aatgaggcac tttttaaatg ggtattttct attattagat
    10261 atctatataa aaaaagatgg agatgaataa acgaaataga ttatctgaac aagaaataaa
    10321 aaaagtagaa cttgacgctt tattgtatat tcggaaaatt tgtcagcaat atcatcttcg
    10381 ctattattta gcttggggta ctttgttggg agccgttagg cataaaggat ttattccttg
    10441 ggatgatgat attgatataa tgatgccacg ttcagattat gagcgattat tggagttagt
    10501 tccttccttg agacatagtt attataaaat cttaagtaat ccaaagaatg aggattatta
    10561 ttatactcat gcaaaaatga tagatactcg tactttgtgt gtggaaaatg atttgcaaac
    10621 tattcaaaat atggggattt gggttgatat tttcccctta g
//
