LOCUS       gnlProkkaONJFHMIH_52   10492 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONJFHMIH_52.
ACCESSION   gnlProkkaONJFHMIH_52
VERSION     gnlProkkaONJFHMIH_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:32:49
            Original ID  :: gnl|Prokka|ONJFHMIH_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10492
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10492
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[141:492]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      142..492
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10492
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10492
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(142..492)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.1e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.1e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(590..1978)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg52_2"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(2226..2621)
                     /locus_tag="ctg52_3"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(2628..3401)
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(3407..3934)
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(3921..5162)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_6"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(5172..6266)
                     /locus_tag="ctg52_7"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(6271..7311)
                     /locus_tag="ctg52_8"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(7330..8340)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_9"
                     /sec_met_domain="PF04055 (E-value: 1.5e-18, bitscore: 57.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 caccctttgt ggagttaatg acttacaaaa agtaaacgga ctgaaatagc ccgtttaact
       61 tctttaactg ttttttatag gcctattatt tgcataggtc ttagaattcc gtggcctctg
      121 tggtgaaata taaattccta tttatgcgac tggtatcacc agttttataa atccatcttt
      181 ctgcatttga gaaagataag ccgatacacg cgactcgtag ccctcttcat tttgaaaatg
      241 gtctgcgagt ttttctataa tctcacgaac attgcgtttt ccatctatca gttcccatac
      301 agccgtaccg tgttcttcca atttcacatg aagttctttc gacattcctt tcggcacaag
      361 gaagcgttgc atccacggat atttaaaacg gggaaaggag agcacaattg tctccccttc
      421 cctttctgct gtaatatgtt cactgcgaca gggaatgacc tctaacaggt tgattttctc
      481 tttggcagcc atacttctta ttttttattt cagagtattc atactgatac ccttttgttt
      541 acaccttgat acaaaattcc tttgttactt taggtattga atttcccagt tacttttgga
      601 tattcgcctc ttccagaccg tatcccttct tcttgttctc tgccttcaac atcaaagcca
      661 caatcagagc aagtacacca aagagagcaa aaatagtcat cggcaacgtg tagtcataag
      721 tctgtgcacc gtctactacc ggacctttgc aataagtatt caacacccat ccgatcaaca
      781 aaggaacacc catcaatccc cagttctgta cccagaaaat caatgcgtat gcggtaccca
      841 actgtttttc cggaataatc ttcggaacag acggccacat agctgaaggc accaacgaga
      901 aggcaaatcc caatataatc atgatgatag tagcaaacca ccatatattc agtataggca
      961 gagcaaacat cgtatgcaca aaaataagca tcactgatcc gattatcatc aatgtggctc
     1021 ccttaccgat acggtcataa agcgaaccga acaacggagt caggataatc gcaccaatcg
     1081 gcaacaatcc gggaatcgtt cccgccaact tcggatctac gttatatttc tgcaccatca
     1141 agtcggcagc atacttgata aaggggaata cagccgagta gaacaataca catagtaatg
     1201 caatcaacca gaatccttta ttggtaataa tatacacaat atctttcata cggaacggtt
     1261 cttccggttc caatccctct gcatccaaag aagcatccaa cttcttatca tagaaagtat
     1321 aaaggaaaaa agcaatcgta cccacgcaca acataatcag acaaaacaaa atcggagcag
     1381 gaatatttgt atggaatgtg ccactctcat ccgtagatcc gaaaaagtct gccaaaggaa
     1441 ctgtcaatac catcgccaga gttgttccga tacgtgccgt agccatttca agtcccatag
     1501 ccaatgccat ttccttgccc ttgaaccatt tcactataat cttggaaaca gtgataccag
     1561 caatctccac acctacacca aagatagcat atcccaatgc agccaacgtc acctgtgttt
     1621 tgaatccgaa gagcatggca ccttccggaa aagtagtaga aatcgcatag tatttcaatc
     1681 cacaaccaaa caccatcaat aagcaagccc ccattccggt gaaacgaact cccatcttat
     1741 ccaaaatgat accaccgaag atcagcatca ataggaatac attaaaccac ccgtaagcac
     1801 ttgtgaagaa accataatca agactgtccc atagtagttc tttctcaagc atgggtttta
     1861 gaggagacat tacgtcggtg aggaaatagc cgcatagcat agtaaatgcg accaatgcta
     1921 gaacactcca tcggagtacg gcggagtcat tcaatttctg tttcaaatgt tctgtcattg
     1981 ttatatttaa aaaagtagtt aataatctta tacagccaac aaaggtagtt aaatctcgtt
     2041 tgtttctatc acaaagagat tgtttttaca agaaaaagtt aagtgcggat tacactgacc
     2101 acgcggaaca ttgaaaatcc gtgtaatctg cgtaatccgc acttaaatat caaagaaatg
     2161 cagcatccgt ctgcaccttc ccattaatgg ttttacccca aagtcttact tgacgacgga
     2221 gtgaattact ctgctgcagg agcaggagtt tcagtagccg gtgccggagt ttctgtagca
     2281 ggtgcattgg tagcaggagc ttcagtttgc ggcgcagccg tacctgcggg taagttatac
     2341 gggttagtct gttgttcttt ctgtgcctgt tccaacactg cgtctttagc aacagcagag
     2401 cgaggaacta cataagcagt agcaatgctc attacaacca taaagatggc caggccccat
     2461 gttgcttttt ccagaaagtc tgtagtcttg cgcacgccca tgatggcgtt agatgaagag
     2521 aaaccagaag caagtccgcc tccttttgag ttctgaatca gcacgatgaa acacatcaac
     2581 aaggctgcaa taaccattaa gataacgaat aataagtaca tttttagtta ttttgaatta
     2641 gcgttaataa tcaatttctc caaaaatctg atttggtctg caaagtaagc attttttttt
     2701 ggatatttca agcttaattt tttaattatt tcaagagctt ttgaatatcg ttgctgttta
     2761 acatagattt ttgccaaagt ttccgtaaaa cagctgtcat cttcctcttc ttcctttatc
     2821 gtttcttctt cggtaagttc gtccgaagag gttggcgaag atggcatttc ttctcttaaa
     2881 ggtttcatgc agaggggaga gtcgctctcg ctcttttcta taaaatcgtc aatcagttcg
     2941 aagcctttga gtttgggcgt ttcttcagcc ggctgttccg tggccggagt ctcctccaaa
     3001 aggaaagagg tgtaatccat cgaatagtcg aaactggtcc gggcagtcac ctcttcgggt
     3061 actgtggaca agaaagcgtc gatcaatgct aatgtgcggt ctacggacgg ttcgtctttc
     3121 agcacctccg tgagaggtac tccctttttc cgtgcctgca catcatagcg gtcaccttca
     3181 atcaaccgga acaactgccg tctgtctgca atgtaaagaa ctgctttccg cagttctcca
     3241 ccgaaactaa tatcatggag aatatacaga ttcttcagat acaacagacg aagtgactga
     3301 aaatacggat acctcgcaag aagattgcgc agttcgtaca aagtatccct attcagcgtc
     3361 tcgggatgct gaatccattg ttgaaagtta acagaagtca tttatattac cagtttgcta
     3421 cagttgcatt aaaaatttgg tcggtgatct ctttagacat ttcagcaatc aatccgtcct
     3481 gtacggcagt caacaactgg gtagagtcgt aggtacggaa cgcagaaaac tgttgttcaa
     3541 agtcttcggc atgattggtg ttgttgacaa aacgcacatt gacggtgata gtcaacttcg
     3601 tctccgaaga ataaccgtcg gcagatactg cctggttgta ctgattgtac cctgtgattt
     3661 ctccgtcaat ctgcaagtcg gcattttgac tcggcttgag cagttgcaga cgggtctgcc
     3721 ggatgaagat atctttcagg tcctcattga atttggttgc caacggagca tatacatact
     3781 ccgacttgat cgggaagtcg gctatcgaaa tggtctttac cttatcataa ttgatagacg
     3841 atccgttaaa cttataggaa acagtgcacg caatgactac caacggcaag ccgaacagta
     3901 gcaaagggcg tattattttc ttaatccaat tcatattctt ttatttttct ataaagtgta
     3961 cgctcggaaa tattcaagtc cttggccgca ctcttccgct ttccatgatg cctctcaagt
     4021 gccttgcgta tcatttcttt ctccacttcg tccagtgaca aaggagattc ttctacatat
     4081 tcttccgtgt cttgtatgtc atcgtcatcc ttgcaaaccg taggctgcat ggtgtgaatg
     4141 atagcaggta ccgaaggttg atgcgccgtc actaccggag tagtaaccac cgttcccatt
     4201 tgccctacct gccccacctg tccggcacgt tccgccatca ggttgtgcac catcttcttc
     4261 agctccgcca cttcctggcg catatcgaac agaacagaat aaagaatctc ccgttcgctc
     4321 tcaaagcctt tactctcacg cgttcccatc agcgcgggaa gacgttgcgt attttgtgca
     4381 ggaagataat tctgcaagat agcagcagag atctccctgt tggtttcaat gatagatatt
     4441 tgctcggtga tgttcttcaa ctgacgaacg ttgccgggcc acgggtaagc caataactct
     4501 ttcttcgcat cctccgtcaa ctggatagca ggcatccggt atttctctgc aaagtctgcg
     4561 gaaaacttac ggaacaacaa gagtacatcg tcaccacgtt cacgcaaagg cggtatctgg
     4621 ataggcaccg tattcaaccg gtaatataaa tcttcacgga aacgtccttc tgcaatcgct
     4681 tgtgtcagat tgacgttggt agctgccacc acacgcacat ccgttttttg tactttggac
     4741 gaacctactt tcataaactc accactctcc agtacacgga gcaaacgtgc ctgggtagac
     4801 atcggcaact cccctacttc atcaagaaaa atagtaccgc cgtcggcttc gccaaagtac
     4861 cctttccgtt cgccaatcgc accggtaaac gcacccttct catgcccgaa cagttcggaa
     4921 tcaatcgtgc cctccggaat agcaccacag ttgacagcaa tatactgtcc gtgcttcctc
     4981 cggctatatt gatgaataat ctgcggaaaa ctttcttttc cgactccact ttctccggta
     5041 atcagcacag acaaatcggt aggagctacc tgaatggcaa catctatggc gcgcgacaat
     5101 gcttcagtat ttccaataat accgaaacgc tgtttcactt gttgtatctc tgctctcgtc
     5161 atcactcgtt tttaatcttc gtctactgta tccagcttca gtttatcact atcgtcacgt
     5221 ttctcgtaat actgtttacg caacggattg gcacgagcca ctttttcccg ctgacgatta
     5281 cggaacacat cgatggcaac atagattgcc tgacggaaag aatcttcaca agccaatccc
     5341 ttgcctgcaa tatcgtatgc cgttccatga gccggagaag tacgtactac cggcaggcct
     5401 gccgtatagt tcaccccgtc ttccatagcc aaggccttga acggagccag cccctgatcg
     5461 tgatacatcg ccaggatacc gtcaaaatga gtataattgc ccgaacccat aaagccgtcg
     5521 gccgcataag gaccgtagca aaggattcct ttctcttcca tttctttcat ggcagggata
     5581 atcacttcct gctcttccat tcccaacaaa ccaccgtctc cggcatgagg attgagagag
     5641 agcaccgcaa tacgcggagc gccgataccg aaatcctgtt tcagacaacg atggaatatc
     5701 atcagtttct cctgaatcag ttctttggta atcgtagtcg cgatctctct gacagggata
     5761 tgtgtcgtca ccaaagccac ccggaagtca ttcttcatca aaatcatcaa tgacttatca
     5821 ccattgccca gacgttcttc gatatattcc gtatgtccgg ggaaggagaa ctcttccgac
     5881 tgaatcgtat gtttgttgat cggagctgtt acgataacat ctatcaaccc ttcgcgatat
     5941 tcttcgatgg cacgttccaa agcccccagc gcagctttac cggcttcggg atcgggtttg
     6001 gaaaattcca ctttcacctc atcatccgta cagttcacca cgctcaaacg gttgtacccc
     6061 gcttcggtag cagagttgac aatgctgaaa ttggtctgta tatccagcgc tttgcgatga
     6121 taagccgcta ctttcggtga gccataaata atcggagtac atagttccaa catcgtaggg
     6181 tcggaaaatg tcttaagaat cacctcatag cccaccccgt taatatctcc ttgggtgata
     6241 cctatcctta tcttgttatc ttccatgttt ttatttatta gtttgttccg cttccttaga
     6301 tgcttctccc aatggaatct gcttctgctg aacttcattc ggaagtttca gtgtatacag
     6361 agatgcttcc atctggcgta ccaggttgcg tttcatttta tcaggtgaat aaacaaatat
     6421 ttctgctgta ataattcgtt ggtttttctc gtccagacga gtatgagaca catacggacc
     6481 acccataaag tcgcccttca tacgccacag gccacgtgct tccattgtgt agctgttctg
     6541 tacattgatc ggacggacat cggtcagcaa actatcggtc gacatataaa cgccttcctt
     6601 gaatccgggg atattggctt tcatcacgga gtcacgtttg tgcacaaaat attctttggt
     6661 aaacgtatcc ttgtcagtgt acggataaga gtacatcaca aagttacggt cggcagtacc
     6721 tgtgttggta gaagcccaga agaaatcatc cccggtcttt gaattagcca gttcggcatc
     6781 cacccagatg tcgcatccga acaaactgtc cactttctgc gaaatgaaat tactgtgttt
     6841 cccttccagg aacgtaatct gacggttcat ttccgcacgg gtaaagaagt cgacaatcgt
     6901 ctttttgttc tcttccacaa acttctcgaa ctcttcttcg ttcggagcct ggatagtcaa
     6961 tatcatctgc ggattggcat atacgtcctt cgcatatttg aacgaggctt tcgtatatat
     7021 atcctgtata tctacaataa taatgttacg tatcaacttc agcgtagaat cataatcttt
     7081 cggcgaagta tacataatcc ggaaagaagg ttccgactgc ggcaaaccgg gcatatcagc
     7141 atcgagcgca tcatgtaaag cccttccggc agcacgatcc caaacaccgt gatctactac
     7201 aaccaaaagc tcgtaagcac gaccactaga ggtgtgattt cctttcagac cacaagatgc
     7261 aacgacaaag gctaccaaag cgatgcataa aataaaagaa tactttttca tgatgttcgg
     7321 ttttatatat taactttcat tatttttctc ctgtttcgct gtcgacagca taccgcaagc
     7381 ggcaaaaata tcttcgcccc tggatgaacg gatagtggtg aaaagtccgt gtgatgtcag
     7441 ataatcacga aaacgggtca tcgtatccat atccgccccc tcgaggtcta cccccggtat
     7501 ggcatgaaaa cgaatcagat tcaccctgca atccagcccg cgaagaagtt tcagcaactc
     7561 tttggcatag acctgcgaat cattgagccc tttaaaaaca atatattcaa acgaaagtcg
     7621 acgttgttta ctaaaatcat agttttttaa cagttccacc atttcggtga ttgaaaacgc
     7681 cttttccgcc ggcattaatt cagcacgctg aacggtcagc ggagagtgaa ggctgatggc
     7741 aaggtggcag tcgttttctt caataaaacg ctgcaatcct ttccgtagcc cgacagtaga
     7801 aagcgtgata cgcttcggac tccatgcgta accgtaggta gcggtcagta gttccaatgc
     7861 cttcaatacc tcatccaggt tatcgagcgg ctcgcccatt cccatcatta cgacattagt
     7921 cagtttgtcc cgttccggca gcgaatgaat ctgattcatg atctggctgg cggtcaggtt
     7981 agcggtatac ccctgtttac cggtcataca gaacttacaa ttcatcttgc aacctacttg
     8041 tgacgacacg cacaacgttg cccggtcatc atccggtata taaaccgact ctacaaaatg
     8101 gttctcaccc actttataaa gatacttcac cgtaccatct acagagcgca tttcatctac
     8161 cggagcttct gctcccacct catagttctg cttgagcaac tcccggtgtt tcaatgacaa
     8221 attagtcata tcatcaatcg aggctacctt cttttcgtaa agccaggatg caatctgctt
     8281 ggcagcaaag ccgggcatac ccagtctttt tgtcaatgat tgaagctcta caagagtcat
     8341 tcctaaaagg ggatatttag acattcttct ttctgttgat agtttatatc tgcaaatgta
     8401 aggaaataaa gtcgatttcc gtatagcagg aatgtaaaag ttaacaaaaa agggaagtat
     8461 gcctccgtta tgattcaacc acgctgatat attgaagtag cttttgcgcc atttcagaat
     8521 cctcgccatt ctttttcact tcatgaccgt acgcctcacg gaaacaagcc agcgcctctt
     8581 cccgttcatt acaaaagctg tacaaaaccc ctaagttctg acaagccaga atcgtatctt
     8641 cttcctccca tcccaaatac ttctttcgca gttcgaactc tctgaagaaa gcctctttcg
     8701 ccattggata attctccaac ttcacataag cctgtgcttt gtaataatat accagacagg
     8761 aagcattagg gtcagcatca tcgtgaatat ccaaagacgt cgcaatacga atcacgttat
     8821 catagtcttt attcatgtaa tactgctgca taatatcaca tctcaatgcc tcatatcgga
     8881 cagtcagttc cgccagacgc ggtttttcgc tgaaatacat ttcatgcaga agagactcac
     8941 ggaagaataa agtagacgcc tgctcatcgc cacgttcatt catcatccgt ttgaattccc
     9001 tgcacagata atacaactgt ttatgacaag cgacgatctg ttttttatta tctatctgta
     9061 tagcaatgtc caacgcctga ttcatcagca tccatgcttc atcgtatcgt ttgatataat
     9121 aaagacattt accctgcata cgcaaacatt tagccactcc accggacagt ctgccattca
     9181 acgactcgtg catttcagct actttccgga atttctcggc agcactctct tcctcatcct
     9241 tatagtaatc acaataagcc agatattcgg aaagttcaat gacttctgcc tgactcttct
     9301 cgtcagcaga agccgcatga taatcaagcg ccctattcaa atagatcgcc gcttcattgt
     9361 attgctcatt gtagtaatat gccaaagcta gatttcgaca ggtgttggca atctccagtt
     9421 ccggagtcgg tactatgttc tcctgcatca ccaatgcttt caggaaacag tcgcatgccg
     9481 tttcgtattc ttcattacgg gcataccgac atccctcatt catcttcaat accgacttgg
     9541 caatgagtgg catggcagca ccttccatac tcttctcact cacagcagct gccgccttcg
     9601 tcagatggaa agaactgctc aagaaagtag ccatatcatt agcaatgaca ggaattaaaa
     9661 aagaatcgat ctcatcaaag tccaattcgg catagacttc aggcgtaact tcaggattgt
     9721 cgttcatgat cgccttccag ctatcttcca acagagaacg attcgtgcga tacagaatct
     9781 cgaaaatctc cacatcacaa atccaatcct tcaatatatc ccattcttgc atcttatagc
     9841 attgataggt aatctccact ttatagcgat acgaatcatg gtagcagaac tgtttcatgc
     9901 gatagttata atcggcaaaa gtcaacggat gggaaaggat ctcttcctca tccagcagag
     9961 cggaaataat ttcatggcga ctatcatcta tacattcgtc atcttgagcg aaatagcgtt
    10021 cgatcgcctc taccatttgt gtgtcaccaa tgcaatatcg tcctcctttg ttggtgagcc
    10081 agctgctcat ttccactctc aactgcgacc aaagtatctg attaatgtct gccatgctct
    10141 tcacttcatc ttcggtaaat ccttctaaag taagtgaaag catcagaagc gttcttccaa
    10201 tctcttcgga accataatca gccgacaaac gccgtagcac actgtcatag aattgcccaa
    10261 cctcattgag ccggcaatat ccacgcatat attcattgag agcatcgtac tgaccgaacg
    10321 aaaccagctc gttgagcaat acactcaaac agcgcggttg tttagccagc acccacgaag
    10381 caagaatatc ttcctgctgt gcagacaaag ccttggagta agtagacaaa tattgctttg
    10441 agaacgactt ggcatccgcc tgtgaaaagc cattcaactg gaaatgagca ta
//
