LOCUS       gnlProkkaJJBIJICI_7    13895 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJBIJICI_7.
ACCESSION   gnlProkkaJJBIJICI_7
VERSION     gnlProkkaJJBIJICI_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:36:49
            Original ID  :: gnl|Prokka|JJBIJICI_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13895
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13895
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3544:3895]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3545..3895
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13895
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13895
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             390..1901
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1974..3041
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             3078..3362
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3545..3895)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="PqqD_RRE (E-value: 4.1e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.5e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3993..5381)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5629..6024)
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(6031..6804)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6810..7337)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7324..8565)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8575..9669)
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9674..10714)
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10733..11743)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_12"
                     /sec_met_domain="PF04055 (E-value: 5.2e-18, bitscore: 57.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 caaccgaaca caccaattga aaaatacagg gaactgcttc ctgacagatg ggaaaaggct
       61 aatgactaaa aagggatcat tagccttttt attttaatac actatataga atcgcggaga
      121 cgcttacgag acgcttacag atgtgaaggg ttaaaaagag aaccttaaat cacaacaaac
      181 atctgtcaca ctacaactta cgtgtccgtg aaacttgtga aaggtacaaa atgattattt
      241 ttaataaatc aaaccaccac gaatttgatt catttccctg cccccaacaa gtcatctcct
      301 tatgattaac aagttttctt cccacaacaa acgggaaaag tcagaagaat catgtacatt
      361 tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt tccaagcagc agtatcaaga
      421 aattggacgc ttataccatt gagaacgaac ctattgcatc aatcgatctg atggaacgtg
      481 cagcaaccgt attaacaaaa gccatcacag acagatggaa tacggagaca ccggtcacta
      541 tctttgccgg accggggaat aatggcggag atgctctcgc cgtagcccgc atgatggctg
      601 aaaaaggata taaaatcgag gtatttctct tcaacacgaa aggagaactt tcacccgact
      661 gccagaccaa taaagaattg gtagaaatga tggaagaagt aaaattccac gaaatcagta
      721 cccaattcgt acctcccgcc ctgacgcccg accatctggt aatcgacgga ttattcggtt
      781 caggcctgaa caaaccgtta agcggcggat tcgctgccgt agtgaaatac atcaattcct
      841 cccctgccat ggtagtagcc atcgacattc cttccggact gatgggagaa gaaaatacat
      901 tcaacgtaaa agctaatatt atccgtgccg acgtaacttt cagtctgcaa ctgccgaagc
      961 tcgcctttct tttcgcagag aacactgaat ttgtcggaga atgggaagtg ctggatatcc
     1021 aattgagcga agacggtatt gaagagatgg agactaacta cgaaatgttg gaaatagaag
     1081 aaatccgttc actcatcaag ccacgcaaac agtttgccca caaggggaac ttcggccatg
     1141 cactattgat tgccggttca aaaggtatgg caggagcctc tgttctcgct gcccgcgcct
     1201 gcctccgttc gggagtaggg ctgctgactg ttcatgcgcc aatgtgcaac aacgacatct
     1261 tgcagacctc catacccgaa gcaatcgtag aaaccgacat caacgaaacc tgttttgccg
     1321 tacctaccga cacggacgac tatcaagcag tcggcatcgg cccgggactg ggacgaaacg
     1381 aggaaacgga agctgcctta ttggagcaac tggaacactg ccagactcct gttgtagtgg
     1441 atgccgacgc acttaatatc ctcgccaacc accgtcatgc ccttacccac ctgccgaagg
     1501 gttccatcct caccccgcat ccgaaagaac tggaacgtct gaccggcaaa tgccaggact
     1561 cttacgaacg tctgatgaag gcttgcgaac tggcccgtgc cgcccatgtc cacattattt
     1621 taaaaggagc ctactccgcc atcatcaccc ccgaaggtaa atgtttcttc aacccaaccg
     1681 gaaatccggg aatggcaacc ggaggtagcg gtgacgtact gaccggagta atcctggcgc
     1741 tgcttgccca aggttatccc accgaagaag ccgctaaaat cggcacttac attcacggat
     1801 tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg aatgatcgca agcgatatta
     1861 tcacctgtct gccgacagca tggcgacttg taagcgaata aaagttaaga acttacagtt
     1921 ttttcaataa cttcattaac tttgttttca aaaccagtta aaaagaaccg aatatgaaaa
     1981 agttgattat agcagcagga ctacttatga caacgtccgc ctatgcacaa accgaagtac
     2041 tgacaggggt tacccgagga aaagactatg gagtggttta cagtcttccc aaaacccaaa
     2101 tagaacttga aataaaagcc aacaaagtca actatactcc gggagaattc agcaaatatg
     2161 ctgatcgtta cctgcgactg accaacgtct ccgccgaccc tgaagagtac tgggaactga
     2221 ctagcgtaaa agtgaaatcc gtaggtgtgc ccaacagcga aacgacgtat ttcgtaaaat
     2281 tgaaggataa gacagtagca ccgctcatgg aactgacaga ggatggcatt gtgaaaacga
     2341 tcaatgttcc ttacagcaac agcagtgtag gcaaaaaagc cgctcccgct cccacagtcc
     2401 tccaaaagaa agcaaatcct cgtgaattcc tgaccgaaga gattctgatg gctagctcta
     2461 ccgccaagat ggccgaactg gtggctaaag aaatctataa catccgcgaa agcaaaaatg
     2521 ccttattgcg cggacaggct gacaatatgc cttcagacgg agcacagctt aagattatgc
     2581 tcgacaatct gaatgcacag gaagaagcca tgacgcaaat gttctccggc acctgcaaca
     2641 aggaagagag aacattcact gtccgcctta cccctgacaa ggaattcaac aatgaagttg
     2701 ctttccgctt ctcgaagaag ttaggtgtag ttgccaacaa tgatttggca ggaactccgt
     2761 tttatatcag tctgaaagac ctgaaatcgg tcaagatacc acaggaagat ggtaagaaga
     2821 agaaagattt ggatggaatc gcctacaacg tacccggaca agctatggtt acattgaccg
     2881 acggcaaaaa gaaactttac gaaggtgaac ttcctattac tcaatttggt gtgatagaat
     2941 atctggctcc ggttttgttc aacaagaatt ctaccatcaa agtttatttt gatccgaata
     3001 cgggaggatt gctcaaagtg gacagagaag aagggaaata gaaaaacgag aaagtgaact
     3061 tctaaaaaac aaagaatatg gttggtgaag gacatgcatt cgacatgata cgccgaataa
     3121 aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc taacgacaag ttgaagcatt
     3181 taaaccgtgc aaacgaacct tatccactac ccaataccac tcccgaagaa atggaacgta
     3241 tcatccacga ctcggagaaa aagaaagaga aagacagcaa ttattttgtt tggggaacgc
     3301 ttattatcat gggagtcctg atagcaattg ccgtcatact ttgggctgta tttatcaaat
     3361 aaataataat aaattcacca cagaggacac ggaggacaca gaggtttaat cttttttatt
     3421 cactatagag taacacagag tctcacgtat tgagaatcgt atttatcgct ctgttttact
     3481 tgcggaaaga gagagaagaa ctctgtgtcc tccgtggcct ctgtggtgaa atataaattc
     3541 ctatttatgc gactggtatc accagtttta taaatccatc tttctgcatt tgagaaagat
     3601 aagccgatac acgcgactcg tagccctctt cattttgaaa atggtctgcg agtttttcta
     3661 taatctcacg aacattgcgt tttccatcta tcagttccca tacagccgta ccgtgttctt
     3721 ccaatttcac atgaagttct ttcgacattc ctttcggcac aaggaagcgt tgcatccacg
     3781 gatatttaaa acggggaaag gagagcacaa ttgtctcccc ttccctttct gctgtaatat
     3841 gttcactgcg acagggaatg acctctaaca ggttgatttt ctctttggca gccatacttc
     3901 ttatttttta tttcagagta ttcatactga tacccttttg tttacacctt gatacaaaat
     3961 tcctttgtta ctttaggtat tgaatttccc agttactttt ggatattcgc ctcttccaga
     4021 ccgtatccct tcttcttgtt ctctgccttc aacatcaaag ccacaatcag agcaagtaca
     4081 ccaaagagag caaaaatagt catcggcaac gtgtagtcat aagtctgtgc accgtctact
     4141 accggacctt tgcaataagt attcaacacc catccgatca acaaaggaac acccatcaat
     4201 ccccagttct gtacccagaa aatcaatgcg tatgcggtac ccaactgttt ttccggaata
     4261 atcttcggaa cagacggcca catagctgaa ggcaccaacg agaaggcaaa tcccaatata
     4321 atcatgatga tagtagcaaa ccaccatata ttcagtatag gcagagcaaa catcgtatgc
     4381 acaaaaataa gcatcactga tccgattatc atcaatgtgg ctcccttacc gatacggtca
     4441 taaagcgaac cgaacaacgg agtcaggata atcgcaccaa tcggcaacaa tccgggaatc
     4501 gttcccgcca acttcggatc tacgttatat ttctgcacca tcaagtcggc agcatacttg
     4561 ataaagggga atacagccga gtagaacaat acacatagta atgcaatcaa ccagaatcct
     4621 ttattggtaa taatatacac aatatctttc atacggaacg gttcttccgg ttccaatccc
     4681 tctgcatcca aagaagcatc caacttctta tcatagaaag tataaaggaa aaaagcaatc
     4741 gtacccacgc acaacataat cagacaaaac aaaatcggag caggaatatt tgtatggaat
     4801 gtgccactct catccgtaga tccgaaaaag tctgccaaag gaactgtcaa taccatcgcc
     4861 agagttgttc cgatacgtgc cgtagccatt tcaagtccca tagccaatgc catttccttg
     4921 cccttgaacc atttcactat aatcttggaa acagtgatac cagcaatctc cacacctaca
     4981 ccaaagatag catatcccaa tgcagccaac gtcacctgtg ttttgaatcc gaagagcatg
     5041 gcaccttccg gaaaagtagt agaaatcgca tagtatttca atccacaacc aaacaccatc
     5101 aataagcaag cccccattcc ggtgaaacga actcccatct tatccaaaat gataccaccg
     5161 aagatcagca tcaataggaa tacattaaac cacccgtaag cacttgtgaa gaaaccataa
     5221 tcaagactgt cccatagtag ttctttctca agcatgggtt ttagaggaga cattacgtcg
     5281 gtgaggaaat agccgcatag catagtaaat gcgaccaatg ctagaacact ccatcggagt
     5341 acggcggagt cattcaattt ctgtttcaaa tgttctgtca ttgttatatt taaaaaagta
     5401 gttaataatc ttatacagcc aacaaaggta gttaaatctc gtttgtttct atcacaaaga
     5461 gattgttttt acaagaaaaa gttaagtgcg gattacactg accacgcgga acattgaaaa
     5521 tccgtgtaat ctgcgtaatc cgcacttaaa tatcaaagaa atgcagcatc cgtctgcacc
     5581 ttcccattaa tggttttacc ccaaagtctt acttgacgac ggagtgaatt actctgctgc
     5641 aggagcagga gtttcagtag ccggtgccgg agtttctgta gcaggtgcat tggtagcagg
     5701 agcttcagtt tgcggcgcag ccgtacctgc gggtaagtta tacgggttag tctgttgttc
     5761 tttctgtgcc tgttccaaca ctgcgtcttt agcaacagca gagcgaggaa ctacataagc
     5821 agtagcaatg ctcattacaa ccataaagat ggccaggccc catgttgctt tttccagaaa
     5881 gtctgtagtc ttgcgcacgc ccatgatggc gttagatgaa gagaaaccag aagcaagtcc
     5941 gcctcctttt gagttctgaa tcagcacgat gaaacacatc aacaaggctg caataaccat
     6001 taagataacg aataataagt acatttttag ttattttgaa ttagcgttaa taatcaattt
     6061 ctccaaaaat ctgatttggt ctgcaaagta agcatttttt tttggatatt tcaagcttaa
     6121 ttttttaatt atttcaagag cttttgaata tcgttgctgt ttaacataga tttttgccaa
     6181 agtttccgta aaacagctgt catcttcctc ttcttccttt atcgtttctt cttcggtaag
     6241 ttcgtccgaa gaggttggcg aagatggcat ttcttctctt aaaggtttca tgcagagggg
     6301 agagtcgctc tcgctctttt ctataaaatc gtcaatcagt tcgaagcctt tgagtttggg
     6361 cgtttcttca gccggctgtt ccgtggccgg agtctcctcc aaaaggaaag aggtgtaatc
     6421 catcgaatag tcgaaactgg tccgggcagt cacctcttcg ggtactgtgg acaagaaagc
     6481 gtcgatcaat gctaatgtgc ggtctacgga cggttcgtct ttcagcacct ccgtgagagg
     6541 tactcccttt ttccgtgcct gcacatcata gcggtcacct tcaatcaacc ggaacaactg
     6601 ccgtctgtct gcaatgtaaa gaactgcttt ccgcagttct ccaccgaaac taatatcatg
     6661 gagaatatac agattcttca gatacaacag acgaagtgac tgaaaatacg gatacctcgc
     6721 aagaagattg cgcagttcgt acaaagtatc cctattcagc gtctcgggat gctgaatcca
     6781 ttgttgaaag ttaacagaag tcatttatat taccagtttg ctacagttgc attaaaaatt
     6841 tggtcggtga tctctttaga catttcagca atcaatccgt cctgtacggc agtcaacaac
     6901 tgggtagagt cgtaggtacg gaacgcagaa aactgttgtt caaagtcttc ggcatgattg
     6961 gtgttgttga caaaacgcac attgacggtg atagtcaact tcgtctccga agaataaccg
     7021 tcggcagata ctgcctggtt gtactgattg taccctgtga tttctccgtc aatctgcaag
     7081 tcggcatttt gactcggctt gagcagttgc agacgggtct gccggatgaa gatatctttc
     7141 aggtcctcat tgaatttggt tgccaacgga gcatatacat actccgactt gatcgggaag
     7201 tcggctatcg aaatggtctt taccttatca taattgatag acgatccgtt aaacttatag
     7261 gaaacagtgc acgcaatgac taccaacggc aagccgaaca gtagcaaagg gcgtattatt
     7321 ttcttaatcc aattcatatt cttttatttt tctataaagt gtacgctcgg aaatattcaa
     7381 gtccttggcc gcactcttcc gctttccatg atgcctctca agtgccttgc gtatcatttc
     7441 tttctccact tcgtccagtg acaaaggaga ttcttctaca tattcttccg tgtcttgtat
     7501 gtcatcgtca tccttgcaaa ccgtaggctg catggtgtga atgatagcag gtaccgaagg
     7561 ttgatgcgcc gtcactaccg gagtagtaac caccgttccc atttgcccta cctgccccac
     7621 ctgtccggca cgttccgcca tcaggttgtg caccatcttc ttcagctccg ccacttcctg
     7681 gcgcatatcg aacagaacag aataaagaat ctcccgttcg ctctcaaagc ctttactctc
     7741 acgcgttccc atcagcgcgg gaagacgttg cgtattttgt gcaggaagat aattctgcaa
     7801 gatagcagca gagatctccc tgttggtttc aatgatagat atttgctcgg tgatgttctt
     7861 caactgacga acgttgccgg gccacgggta agccaataac tctttcttcg catcctccgt
     7921 caactggata gcaggcatcc ggtatttctc tgcaaagtct gcggaaaact tacggaacaa
     7981 caagagtaca tcgtcaccac gttcacgcaa aggcggtatc tggataggca ccgtattcaa
     8041 ccggtaatat aaatcttcac ggaaacgtcc ttctgcaatc gcttgtgtca gattgacgtt
     8101 ggtagctgcc accacacgca catccgtttt ttgtactttg gacgaaccta ctttcataaa
     8161 ctcaccactc tccagtacac ggagcaaacg tgcctgggta gacatcggca actcccctac
     8221 ttcatcaaga aaaatagtac cgccgtcggc ttcgccaaag taccctttcc gttcgccaat
     8281 cgcaccggta aacgcaccct tctcatgccc gaacagttcg gaatcaatcg tgccctccgg
     8341 aatagcacca cagttgacag caatatactg tccgtgcttc ctccggctat attgatgaat
     8401 aatctgcgga aaactttctt ttccgactcc actttctccg gtaatcagca cagacaaatc
     8461 ggtaggagct acctgaatgg caacatctat ggcgcgcgac aatgcttcag tatttccaat
     8521 aataccgaaa cgctgtttca cttgttgtat ctctgctctc gtcatcactc gtttttaatc
     8581 ttcgtctact gtatccagct tcagtttatc actatcgtca cgtttctcgt aatactgttt
     8641 acgcaacgga ttggcacgag ccactttttc ccgctgacga ttacggaaca catcgatggc
     8701 aacatagatt gcctgacgga aagaatcttc acaagccaat cccttgcctg caatatcgta
     8761 tgccgttcca tgagccggag aagtacgtac taccggcagg cctgccgtat agttcacccc
     8821 gtcttccata gccaaggcct tgaacggagc cagcccctga tcgtgataca tcgccaggat
     8881 accgtcaaaa tgagtataat tgcccgaacc cataaagccg tcggccgcat aaggaccgta
     8941 gcaaaggatt cctttctctt ccatttcttt catggcaggg ataatcactt cctgctcttc
     9001 cattcccaac aaaccaccgt ctccggcatg aggattgaga gagagcaccg caatacgcgg
     9061 agcgccgata ccgaaatcct gtttcagaca acgatggaat atcatcagtt tctcctgaat
     9121 cagttctttg gtaatcgtag tcgcgatctc tctgacaggg atatgtgtcg tcaccaaagc
     9181 cacccggaag tcattcttca tcaaaatcat caatgactta tcaccattgc ccagacgttc
     9241 ttcgatatat tccgtatgtc cggggaagga gaactcttcc gactgaatcg tatgtttgtt
     9301 gatcggagct gttacgataa catctatcaa cccttcgcga tattcttcga tggcacgttc
     9361 caaagccccc agcgcagctt taccggcttc gggatcgggt ttggaaaatt ccactttcac
     9421 ctcatcatcc gtacagttca ccacgctcaa acggttgtac cccgcttcgg tagcagagtt
     9481 gacaatgctg aaattggtct gtatatccag cgctttgcga tgataagccg ctactttcgg
     9541 tgagccataa ataatcggag tacatagttc caacatcgta gggtcggaaa atgtcttaag
     9601 aatcacctca tagcccaccc cgttaatatc tccttgggtg atacctatcc ttatcttgtt
     9661 atcttccatg tttttattta ttagtttgtt ccgcttcctt agatgcttct cccaatggaa
     9721 tctgcttctg ctgaacttca ttcggaagtt tcagtgtata cagagatgct tccatctggc
     9781 gtaccaggtt gcgtttcatt ttatcaggtg aataaacaaa tatttctgct gtaataattc
     9841 gttggttttt ctcgtccaga cgagtatgag acacatacgg accacccata aagtcgccct
     9901 tcatacgcca caggccacgt gcttccattg tgtagctgtt ctgtacattg atcggacgga
     9961 catcggtcag caaactatcg gtcgacatat aaacgccttc cttgaatccg gggatattgg
    10021 ctttcatcac ggagtcacgt ttgtgcacaa aatattcttt ggtaaacgta tccttgtcag
    10081 tgtacggata agagtacatc acaaagttac ggtcggcagt acctgtgttg gtagaagccc
    10141 agaagaaatc atccccggtc tttgaattag ccagttcggc atccacccag atgtcgcatc
    10201 cgaacaaact gtccactttc tgcgaaatga aattactgtg tttcccttcc aggaacgtaa
    10261 tctgacggtt catttccgca cgggtaaaga agtcgacaat cgtctttttg ttctcttcca
    10321 caaacttctc gaactcttct tcgttcggag cctggatagt caatatcatc tgcggattgg
    10381 catatacgtc cttcgcatat ttgaacgagg ctttcgtata tatatcctgt atatctacaa
    10441 taataatgtt acgtatcaac ttcagcgtag aatcataatc tttcggcgaa gtatacataa
    10501 tccggaaaga aggttccgac tgcggcaaac cgggcatatc agcatcgagc gcatcatgta
    10561 aagcccttcc ggcagcacga tcccaaacac cgtgatctac tacaaccaaa agctcgtaag
    10621 cacgaccact agaggtgtga tttcctttca gaccacaaga tgcaacgaca aaggctacca
    10681 aagcgatgca taaaataaaa gaatactttt tcatgatgtt cggttttata tattaacttt
    10741 cattattttt ctcctgtttc gctgtcgaca gcataccgca agcggcaaaa atatcttcgc
    10801 ccctggatga acggatagtg gtgaaaagtc cgtgtgatgt cagataatca cgaaaacggg
    10861 tcatcgtatc catatccgcc ccctcgaggt ctacccccgg tatggcatga aaacgaatca
    10921 gattcaccct gcaatccagc ccgcgaagaa gtttcagcaa ctctttggca tagacctgcg
    10981 aatcattgag ccctttaaaa acaatatatt caaacgaaag tcgacgttgt ttactaaaat
    11041 catagttttt taacagttcc accatttcgg tgattgaaaa cgccttttcc gccggcatta
    11101 attcagcacg ctgaacggtc agcggagagt gaaggctgat ggcaaggtgg cagtcgtttt
    11161 cttcaataaa acgctgcaat cctttccgta gcccgacagt agaaagcgtg atacgcttcg
    11221 gactccatgc gtaaccgtag gtagcggtca gtagttccaa tgccttcaat acctcatcca
    11281 ggttatcgag cggctcgccc attcccatca ttacgacatt agtcagtttg tcccgttccg
    11341 gcagcgaatg aatctgattc atgatctggc tggcggtcag gttagcggta tacccctgtt
    11401 taccggtcat acagaactta caattcatct tgcaacctac ttgtgacgac acgcacaacg
    11461 ttgcccggtc atcatccggt atataaaccg actctacaaa atggttctca cccactttat
    11521 aaagatactt caccgtacca tctacagagc gcatttcatc taccggagct tctgctccca
    11581 cctcatagtt ctgcttgagc aactcccggt gtttcaatga caaattagtc atatcatcaa
    11641 tcgaggctac cttcttttcg taaagccagg atgcaatctg cttggcagca aagccgggca
    11701 tacccagtct ttttgtcaat gattgaagct ctacaagagt cattcctaaa aggggatatt
    11761 tagacattct tctttctgtt gatagtttat atctgcaaat gtaaggaaat aaagtcgatt
    11821 tccgtatagc aggaatgtaa aagttaacaa aaaagggaag tatgcctccg ttatgattca
    11881 accacgctga tatattgaag tagcttttgc gccatttcag aatcctcgcc attctttttc
    11941 acttcatgac cgtacgcctc acggaaacaa gccagcgcct cttcccgttc attacaaaag
    12001 ctgtacaaaa cccctaagtt ctgacaagcc agaatcgtat cttcttcctc ccatcccaaa
    12061 tacttctttc gcagttcgaa ctctctgaag aaagcctctt tcgccattgg ataattctcc
    12121 aacttcacat aagcctgtgc tttgtaataa tataccagac aggaagcatt agggtcagca
    12181 tcatcgtgaa tatccaaaga cgtcgcaata cgaatcacgt tatcatagtc tttattcatg
    12241 taatactgct gcataatatc acatctcaat gcctcatatc ggacagtcag ttccgccaga
    12301 cgcggttttt cgctgaaata catttcatgc agaagagact cacggaagaa taaagtagac
    12361 gcctgctcat cgccacgttc attcatcatc cgtttgaatt ccctgcacag ataatacaac
    12421 tgtttatgac aagcgacgat ctgtttttta ttatctatct gtatagcaat gtccaacgcc
    12481 tgattcatca gcatccatgc ttcatcgtat cgtttgatat aataaagaca tttaccctgc
    12541 atacgcaaac atttagccac tccaccggac agtctgccat tcaacgactc gtgcatttca
    12601 gctactttcc ggaatttctc ggcagcactc tcttcctcat ccttatagta atcacaataa
    12661 gccagatatt cggaaagttc aatgacttct gcctgactct tctcgtcagc agaagccgca
    12721 tgataatcaa gcgccctatt caaatagatc gccgcttcat tgtattgctc attgtagtaa
    12781 tatgccaaag ctagatttcg acaggtgttg gcaatctcca gttccggagt cggtactatg
    12841 ttctcctgca tcaccaatgc tttcaggaaa cagtcgcatg ccgtttcgta ttcttcatta
    12901 cgggcatacc gacatccctc attcatcttc aataccgact tggcaatgag tggcatggca
    12961 gcaccttcca tactcttctc actcacagca gctgccgcct tcgtcagatg gaaagaactg
    13021 ctcaagaaag tagccatatc attagcaatg acaggaatta aaaaagaatc gatctcatca
    13081 aagtccaatt cggcatagac ttcaggcgta acttcaggat tgtcgttcat gatcgccttc
    13141 cagctatctt ccaacagaga acgattcgtg cgatacagaa tctcgaaaat ctccacatca
    13201 caaatccaat ccttcaatat atcccattct tgcatcttat agcattgata ggtaatctcc
    13261 actttatagc gatacgaatc atggtagcag aactgtttca tgcgatagtt ataatcggca
    13321 aaagtcaacg gatgggaaag gatctcttcc tcatccagca gagcggaaat aatttcatgg
    13381 cgactatcat ctatacattc gtcatcttga gcgaaatagc gttcgatcgc ctctaccatt
    13441 tgtgtgtcac caatgcaata tcgtcctcct ttgttggtga gccagctgct catttccact
    13501 ctcaactgcg accaaagtat ctgattaatg tctgccatgc tcttcacttc atcttcggta
    13561 aatccttcta aagtaagtga aagcatcaga agcgttcttc caatctcttc ggaaccataa
    13621 tcagccgaca aacgccgtag cacactgtca tagaattgcc caacctcatt gagccggcaa
    13681 tatccacgca tatattcatt gagagcatcg tactgaccga acgaaaccag ctcgttgagc
    13741 aatacactca aacagcgcgg ttgtttagcc agcacccacg aagcaagaat atcttcctgc
    13801 tgtgcagaca aagccttgga gtaagtagac aaatattgct ttgagaacga cttggcatcc
    13861 gcctgtgaaa agccattcaa ctggaaatga gcata
//
