LOCUS       gnlProkkaGACADLOM_15   12576 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GACADLOM_15.
ACCESSION   gnlProkkaGACADLOM_15
VERSION     gnlProkkaGACADLOM_15
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:44:47
            Original ID  :: gnl|Prokka|GACADLOM_15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 59343
            Orig. end    :: 71919
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12576
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12576
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12576
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(351..1136)
                     /locus_tag="ctg15_48"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     WRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(1160..2326)
                     /locus_tag="ctg15_49"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(2339..2908)
                     /locus_tag="ctg15_50"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             complement(2942..3478)
                     /locus_tag="ctg15_51"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3520..5064)
                     /locus_tag="ctg15_52"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVVLIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5257..5481)
                     /locus_tag="ctg15_53"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             5754..6587
                     /locus_tag="ctg15_54"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             7053..8564
                     /locus_tag="ctg15_55"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8638..9702
                     /locus_tag="ctg15_56"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9724..10011
                     /locus_tag="ctg15_57"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_58"
                     /sec_met_domain="PF05402 (E-value: 5.8e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-09, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10393..11781)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_59"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(12072..12467)
                     /locus_tag="ctg15_60"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPVAE"
ORIGIN
        1 aggtcaacca aagtatcaat ctgatacaaa gggatgccac gcatcaggcg acggcgcagc
       61 gcttctgccg acggacgata acgccccgga tcttttccgc aacgcttata agcctcacgg
      121 gtagcagcaa tcacaggttg caacttaatg tctgccattt gggtggtggt agtcaagtct
      181 tctgtgaaaa tatttatttc tttccaaagt ccatcgcaat aagcagtatt cttcactgct
      241 gcatatacgg ctgctccggc aaaaacaggg caggcgttct ttatttcctg agatactttt
      301 atttcaaaca tacttttatt caagtttata tcaacttacg ttcaagtcta ttatttatga
      361 atcatgatcc ccgacagaat ccgtccggac ttaatgccca aacgccttgc cgagaaaaac
      421 tcgtcgtgat gaatatacgt acatatccgg gcaagctcca cttgtccgga cggcacaccg
      481 aaagcaagga tttgcatccg gttcgcttcc cacaagtcga tatgatgttt tccggtttcc
      541 tctttcctga tagaaatacg aggcatatca aaaccattct tctgaaatgc ttcgtacact
      601 tcctcaccca cttcaaaaga agccaatgag atactcggac cgatacaggc tatcacatct
      661 tctccacttg tgccaaactc cttctccatc cgcaacaaag tatcacgcac gatgtatgct
      721 accgtccctc tccatccggc atgaatggca gctatggcac tatgtttctt atcatatatc
      781 aacacaggaa cacaatccgc agtagaaata caaagacaat atcccggctc gcgggtaatc
      841 aaagcatcca ctccgtgcag catctcctgt cgttgttgag acgaagccga taaataagca
      901 tccccgatca gcaggcaatt cgtctcatga gtctgcacag gaatcaccag ttcttcgggt
      961 gtctgcgaca ttccttccat cagaagcgtt tgattccgcc agaccttttc cgcctcgtct
     1021 ccactgtagg gcgtacagtt gaatgacgca taatttcctt cgctgcaccc tccctgccgg
     1081 gtagttacaa aatgagaaat gttggagtat gagcttaacg actcataccc caacattctt
     1141 ttatctcttg tgattgaaat catttttctt cccaatcctc ttcttcgtat tcgtagtcga
     1201 gatcatcatc gtcgtcgtca gcgtcttcct catattcata gtcgagttct tcatcctcgc
     1261 ccatgtcctt gagttcctgc tgcagacggg tcacgtcttt cggacggtga acaatgtctt
     1321 ctatcttatt actttccttg ttcagttcct cccacagaat gtctttcaac actgagattc
     1381 ccaaaccaga aacagaagaa atgaatatat gcggaacacc ctcgggcaat gtcggttcaa
     1441 tctcgtccat cagctcctga tcgagcatat cgctcttcgt gatagccagc acacgttgtt
     1501 tgtccagcat ttcgggattg aacgtacgca actcattcag caatacttca tactccttgc
     1561 ggatatcatc gctatctgcc ggaaccatga acaacagcaa cgagttacgc tcgatatgac
     1621 gcagaaaccg cagtcccaat ccttttccct gactggctcc ctcgatgatg cccggtatgt
     1681 ccgccatcac gaatgacttt ccatcgcgat aggaaacaat tcccagattc ggttcgagtg
     1741 tcgtaaacgg gtaatcggca atcttcggtt tcgcagccga aatagcagaa agcaacgtag
     1801 actttcccgc attcgggaaa cctaccagcc ctacatctgc caacagtttc agctccatga
     1861 tcaccgtcat ttcctgcatc ggttcgcccg gctgcgcaaa gcgcggagcc tgacgggtag
     1921 ccgtcttgaa atgactgtta ccctgaccgc cacgaccgcc tttcagcaag atcacttcct
     1981 gtccgtcgtc cgtcacatcg caaaggtatt ctccggtttc ggcgttatac actaccgttc
     2041 cgcagggtac ttcgatcact ttatccgcac cgtcttttcc gaaactacgg ttcttgctgc
     2101 ccgattcgcc atgacctgcc atcgcatgac ggtcatactt caagtgaagc aatgtccagt
     2161 aattacggtt accgcgcaag ataatatggc ctcctcttcc accatcgccc ccatcgggac
     2221 ctccgttagg acaatatttc tcgcgcctca tgtgcgtaga gcctcttccg cccttgcctg
     2281 agcgacagta tatctttacg taatcaacaa aattcgattc agccatattt tttatttatt
     2341 ataatttgtc tactgcttcg cagatatcag cgaagatacc atccatagta cccagaccgt
     2401 tgatgtgctg gtatttcttt tcgttcttgt accagtcgat cagcggagat gtctgtgaat
     2461 gatatacatg cagacgtttt ttgattgttt cttcgttgtc gtcggcacga ccggagtctt
     2521 tgccacgttt gatcagacgt accatcagtt catcttccgg aacttcgaga tccaacatta
     2581 cagaaacatc ctgtcctctt tccgccaaca tcttctttaa tgcttccgcc tgtgcaattg
     2641 ttcttgggaa accgtcgaaa attacacctt tgctgtcttt gaagctatcg aatacacttg
     2701 ccagaatatc aatcatcaat tcatccggaa tcaactgccc ctggtcgatg taacctttag
     2761 cagttttgcc cagttccgtg ccgttcttga tttctgcacg caatacatct cctgtcgaga
     2821 tgtggttgat tccatacttt tctacaatac gttcgctctg cgttcctttt cctgaacccg
     2881 gagcaccgaa aattacaatg ttcaacatct ttttaaccta aaaattaatt tgtatttgaa
     2941 tttaatctac tacagtataa atatcgggat aattgcgtcc gaaaccatca taatccaatc
     3001 cgtagccaac gataaaatca ttcggtattt ccatcgctac atattctatg ttcagattga
     3061 ccttcagctt ttccggtttc accagcaaag aggcgatatg aatcgcttcg gggttgcgtg
     3121 tgcccagtgt atccagcaga cgctgcatcg tcagtccggt atctacaata tcttctacga
     3181 tcactaccgt acgtccggca atgtcttcat tcagcccgat cacttcttta attactccgg
     3241 tggaagtcac cccctgataa gatgccaact tcacgaatga aatttcgcac ggaatcgtaa
     3301 tatgcttcag caagtcggcg gtaaacatga acgagccgtt caacacactg aggaagagcg
     3361 gattcttacc tgccaaatca cgattgattt cgttcgctac gcgaatcact tctttttgaa
     3421 tatcctgttc cttaatggaa acagtaaatt gcttgtcttt tatctgtatg gtatccataa
     3481 ccggtcattt taaaaaagtt gtcgcaaaaa tacaattttt tattctaccc cgtgcatcat
     3541 cttctgtaat ttcttcgaga gaaggaacag aatcagtgag gcaacaccgg acataatgac
     3601 gaacagcatg aagaagtcgt acatggtagc aatctgataa ccaaggattg atttcacttt
     3661 tccgtcttcg ggatagagac cgctcagcat acctgcaaat ttatttgcgg tggcggtaga
     3721 aagataccag atccccatca tcaaggaggc gaaacgtaac ggactcaact tattaaccat
     3781 agaaagcccg ataggtgaca gagcgatttc tcccattgta tgaataaagt aaagccctgt
     3841 cagccagatc atgctcacct ttactcccgg aatagcatct ttcactccaa aacagatgaa
     3901 gagataacca agagaaagca gcaacagacc gattgcctgt ttggtagggg aagccggttc
     3961 catgtttcgc ttattcagaa agccccatat accgggcata atataggcaa ggatcactac
     4021 aaaaagcgga ttgaatgact ggaaccacga agccggcatc tcccagccga aaatgctgcg
     4081 gtcagtctgt tcggaagcga ataatgtcag agaagctcct gcctgctcgt aagctgccca
     4141 gaagaaaatg acgaagaaag ctacgatata gattacgaaa atacggctac gttctacttt
     4201 ggtcaatgaa ccatccagca gaatgagcac tggaaagaca atacaagccg taaagatacc
     4261 cacactaatc cagtcatcgc taaaggcata gctaaaaaag gctattaaga caactgtaag
     4321 ggcagtaatg atgataatat tacgtacttt ggtacgtttg tccatcttcg gatgtgaaat
     4381 atgttcggct ttatcctcct ttttttcacg tctggcgtcg gggacgatac caatcggttc
     4441 accggaagga gagaaaaggt atttattctt ctgagtttca aagaggacaa cagtgaacag
     4501 cgtcatgatt ccggatgcga ggaatcccca tttaaagtcc tgcggattcc ctgtgtctcc
     4561 caagaaaccg caaatcaaag gagcagcgaa agaacctaca ttaacaccca tatagaaaat
     4621 ggtgtatgca gcatccaacc gtttgtcccc gggttcatat aattgcccga cgagcgaaga
     4681 aacggtaggc ttaaagcaac cgttacctaa aatcatgaat ccgagtccgc catacatcag
     4741 ccagtgggca aggtctgtat tgttcagtga agaggcactc ataaacatca ggaactgacc
     4801 gactgccatc atcaccgctc cccaaaatac cgaacgacgg atgccccaat atttatcggc
     4861 aatgtatccg ccgatcaacg gagtcagata gaccagtccg gtgtagctac cgtagataga
     4921 ggccgccgct tctttatcaa aaagcaatgc ctgcgtcaga aagaggataa agatagcacg
     4981 cataccgtag taactgaaac gttctgccgt gctcgttgcg aaaattaggt aaaggccttt
     5041 cgggtgccct ttcaatgaac tcatgaatta tgtgtttagt agtttatggg gtgcaaaggt
     5101 actaaaaagt agattaaatg cctcaaaaaa gaagattctt atggaataga aaaatacagg
     5161 atggcgtgca aaaagtctca gttacccacc ttattatgtt ttcaacagtg taaataatca
     5221 agtggatatt ctccttaaat gtgggtcagt ccccatttat ccaaaggtaa attcaacatt
     5281 ctcaatactg gcatagagca ttccttcttt ttttctaagc aggattttgt tttcccttgc
     5341 cagccaaccg atagcaattg ctacatcctc gaacgtcaaa cctaactcat ggcacaaagt
     5401 gaacatagac tgttcgccct tttcatttaa gatgcgccat actttcccgg catttgagcc
     5461 aattcttttc ttttccatca tgcaaacttt agaagattaa acaatttata tttataatct
     5521 aaacattgtg agcacaggag aataacgtaa agcacattac tgcactacaa agatatcatt
     5581 tttttcgaaa aaagcaaata atcaaggcat tagctgctat tattagttac attctaatca
     5641 tttatgccga tctctgctaa aaaatagcac aaataaagaa acagttcaat tctttttcat
     5701 aagtttgcag acgagaacta aactaatatc gcacatttaa aactttaatt agcatgacta
     5761 ccaaaaaact aacaggaata ctttcgttat tcctttgtat tatttgcctc gtgagctgta
     5821 atgacaatga tgacaacttt tctccaatca ctctggaata tgaagatcct caaattaagt
     5881 tcgacaacga gagccgttct tacacactga ctccgttcag caaagaaacg acaccactct
     5941 tcatcaaggg tggagacgga acttacaaag tgaccaatga gaatgagaaa gtggtacaag
     6001 taaactacca caacggaagt ttaacattga aggcaaagga aataggacgc gcatccatca
     6061 agatagaaga cagttcgaat aatatgtata tactgtctgt cgttgtaaaa tatcgtactc
     6121 ttactcataa ggcgtttaca gcaaaagtca ttgtgaaggg agacgagctt acatctgaag
     6181 aacacactga gttaatgaac aaagtgggca attcatatcc gattaataaa tatgtattta
     6241 cttttatgaa tgcggaagac agcaaaggaa cagtagattt gtattattca gataataaca
     6301 tgaaaacagg caactttgaa aaagaacata tagtgctgga tgaagaaaat gccattccca
     6361 tcaaaggtga atacaaattg agtgagtatt atcgtataac aatcaaagaa gataatggca
     6421 aagttattga tactttctat attaccaaga actttctacc actcctcaat acaagaatga
     6481 atgctcatcc gttaattcag tactgttttg tcagagattt aaccgcacag tacaaacaag
     6541 attaccttgc actggaaaat gcatatctga ttcaaatagc agaatgagaa ctacactgat
     6601 tttcttcttt agcagagtga atagagtatt tattatatga gcaaactccc cattagattt
     6661 agcaaaaaac aataagctat tagctaatca agaatatgcc catagcatat ttatcacaat
     6721 cacctcttcc acccttttcc tgaacctttg atgaataagg cgattgcggg tgaaagaggt
     6781 gaaccagagg aatatacagt agtagaaaca cgcatgggaa ggttaacaaa cagccatgaa
     6841 tgttctccgg agagagtaaa agtaaatgag ataacaatca ttaatatctg acttctcaac
     6901 tattaataac tgacacatca actattaata cctgacaact caagtattaa tacctgaagt
     6961 tccttcccaa aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggaac
     7141 gtgccgcaca ggcactgact aaagccatca ccaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccatcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgccagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacac cggaacatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg gctgatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggacgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggag ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcactgatc aaaccacgcc aacaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggc tcaaaaggaa tggcaggtgc atcggtactg gccgcccgtg
     7861 cctgtctgcg atcgggagta ggtctgctga cggtacacgc gccgttatgc aacaacgata
     7921 ttctgcaaac gtccgccccc gaagccatgg tagaaacaga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattaccaag ctgtcggcat cggtccggga ctcggtcgca
     8041 acgaagaaac ggaagccgcc ctgatagaac aactggaaca ttgtcagact ccgacggtac
     8101 tggatgccga cgcactcaat attctggcca atcaccggca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag agctggaacg cctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggcgca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cccgccgaag acgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtgacttg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacgcg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaacaaa gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ctgaacagtg tcaaagtgaa acctgtaggt gtaccaaaca gcgaagctac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaatg tcccctacag cagtaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttt ctcacagaag aaattctgat ggcaagttca
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccttcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaagcc atgaccgaga tgttttcggg agtccgcaat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aggaattcga caatgaggta
     9361 gctttccgct tttcaaagaa gctgggtata gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
     9481 aagaaagaga tggaaggcat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaagcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgcttat cattatgggc
     9961 gtactgatag gatgtgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatattg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
    10141 ctatcaggtt ccatacggcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggt atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt tcagatagaa
    10381 tatatactgt gattatttct gaatatttgc ttcttccagt ccgtagcctt tcttcttgtt
    10441 ttccactttc agcatcaagg caacaatcag ggcaagtaca ccgaacatag caaaaatagc
    10501 catcggcaag gtataatcat aagtctgtgc accatctaca accggacctt tgcaataaga
    10561 gttcaacacc catccgatca gcaaaggcac gcccatcaat ccccagttct gtacccaaaa
    10621 gatcaacgca taagccgttc ccaactgttt ctccggaata atcttcggaa ccgaaggcca
    10681 cattgccgaa ggaaccaatg agaaagcaaa tcccagaata atcatgatca ccgttgcaaa
    10741 ccaccatata ttcagaatag gaagagcgaa catcgtgtgt acgaaaatca gcatcaccga
    10801 cccgatcacc atcagcgtgg ctcccttacc gatacggtca tataatgaac cgaacaatgg
    10861 tgtcaggatg atcgcgccaa tcggcagcaa tccgggaatc gttcccgcaa gtttcggatc
    10921 aacattgtac ttctgtacca tcaaatcggc cgcatacttg atgaagggga atacagccga
    10981 atagaacaat acgcacagta atgcgatcag ccagaatcct ttgttggtaa tgatatagac
    11041 aatgtctttc atgcggaaag gttcttccgg ttccagtcct tccgcatcca gtgaagcatc
    11101 cagtttctta tcgtagaaag tatagatgaa gaatgcgatg gtacctacgc acaacatgac
    11161 gagacagaac agaatcggag cgggaatatt ggtatggaat acgccgctct catccgtaga
    11221 cccgaagaag tctgccaaag gaacggtaag caccatggcc aaagttgttc caatacgcgc
    11281 ggtcgccatt tccagtccca tagcgagagc catctctttg cctttaaacc acttcacgat
    11341 aatcttcgaa acggtgatac ccgcaatttc gactcctaca ccgaaaatag cataacccaa
    11401 tgcagccaat gtgacttgca tcttgaatcc gaaaagcatc gcaccttccg ggaaagtagt
    11461 agtaatagca taatatttca atccacaacc gaacaccatc aataaacagg cacccattcc
    11521 ggtgaagcgt actcccatct tatccagaat gataccacca aagatgagca tcagcaggaa
    11581 tacattaaac cagccataag cactggtgaa aaaaccgtaa tctaaactgt cccagagaag
    11641 ttctttttca agcatgggtt tcagaggaga cataacgtct gtgaggaagt agccgcacaa
    11701 catggtaaaa gcgactaatg ctagaacact ccaacgcagc actgcggagt cattcagctt
    11761 ttgtttcaat tgttctgtca ttgtaatatt taaaaggagt taataatctc gtaacgggca
    11821 acaaagttaa ctaattatca tttgttttac taaaaaagga gaacatttta taagaaaaag
    11881 gacatctgac cggatattcc tgtatgaaga agagcagacc gggcccaata ataaagacag
    11941 acgcgaacta cacgtattac acgattctat tagaatctct tgtaattcgc gtaattcgcg
    12001 cctataatga agagaacggg tcaaaaagcc cgttcactca ataagtttaa accgaatatc
    12061 ctgtcactga attattctgc tacaggagca ggagtttcag tagccggagc ttccgttgct
    12121 ggtgcagact ctgcaggagc agtagcatct gtctgaggag cagcagtacc ggtaggcata
    12181 ttatacgggt tggtttgttg ttctttctgt gcttgttcca acaatacatc tttagctgca
    12241 gaagaagaag gaacaacgta agcagtagca acgctcatca caaccatgaa gatagccaga
    12301 ccccaagttg ctttttccag aaaatctgta gtcttgcgca cgcccatgat agcgtttgat
    12361 gaagaaaaac cagaagcaag tccgcctcct tttgaattct gaatcagcac gatgaagcac
    12421 atcagcaagg ctgcaatcac cattaagata atgaataata agtacatttt tagttatttt
    12481 gaattagcgt taataatcaa tttctccaaa aatctgattt ggtctgcaaa gtaagcattt
    12541 ttttttggat atttcaagct taatttttta attatt
//
