LOCUS       gnlProkkaGJBBNPDD_114   5164 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GJBBNPDD_114.
ACCESSION   gnlProkkaGJBBNPDD_114
VERSION     gnlProkkaGJBBNPDD_114
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:42:20
            Original ID  :: gnl|Prokka|GJBBNPDD_114
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5164
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5164
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1499:5162]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1500..5162
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5164
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5164
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..277
                     /locus_tag="ctg114_1"
                     /transl_table=11
                     /translation="MYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKK
                     QIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             288..1436
                     /locus_tag="ctg114_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1500..2219
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg114_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.5e-17, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2240..3541
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg114_4"
                     /sec_met_domain="CTP_transf_like (E-value: 9.2e-14,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.5e-122, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3558..4682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg114_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.3e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4692..5162
                     /NRPS_PKS="Domain: Aminotran_5 (28-156). E-value: 1.6e-11.
                     Score: 35.5. Matches aSDomain:
                     nrpspksdomains_ctg114_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg114_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.6e-10, bitscore:
                     29.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGA"
     aSDomain        4776..5159
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg114_6_Aminotran_5.1"
                     /evalue="1.60E-11"
                     /label="ctg114_6_Aminotran_5.1"
                     /locus_tag="ctg114_6"
                     /protein_end="156"
                     /protein_start="28"
                     /score="35.5"
                     /tool="antismash"
                     /translation="ICPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDI
                     CLNSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENP
                     DIAMVYTTHHETGTGILNPIREMG"
ORIGIN
        1 ttcttatatg aagggaaaga atgtggatta ttacctgaat caggccggtg gctgttctga
       61 taatgcaagg aagagtaaga agttcattgt ttacatgaat ggtcaggtga cgaaggttaa
      121 gggtagtggt aagaaacaga ttgagccggg gtgtgagatt attgtgcctg gtaaggctaa
      181 gaagaaaggg aacatagcta atattttagg ttatgctact tccttcagtt ctttgggaat
      241 gatgattgct tctattgcta atttgataaa gaaataaatg acctattatg attgaaaagc
      301 aatcttatca agaaccgttt tctgaagtgg ataaaaggaa agatgatgaa atggaaatag
      361 acttgatggc tattttttat aagattatta ctgttcgtgg agtactatgc aaagctgctg
      421 gagtgggagt aataattgct atagtggtgg cattgagcat tcccaagcaa tatacagtaa
      481 aggttaccct ttctcctgaa atgggtaatg cgaagggaag taatggttta gccggacttg
      541 ctgcctcgtt tttgggagat ggggctctaa taggggaaag cacagatgcc ttgaacgctt
      601 ctctttcagc agatattgtt tcttcaactc cttttttatt ggaactttta gaaatggaag
      661 tctccgtttc taaaaaggat gataaaatga ctttggggtc ttatctcgat gaagagtcat
      721 ctccttggtg ggattatctt ataggttttc cgggcatagt aataggagga gttaaatcat
      781 tattcggaga agatacggtt cctgccagtg gagggcggca aggaactatc gaattgacga
      841 aagaagtaaa tgagaagatt aattttctta aaaagaagat tagtgcatcc attgataaga
      901 aaaccgccat aacgagcatt acggtcacct tacaaaatcc gcagatcact gcggttatag
      961 cagattctgt cgttcataaa ttacaggaat atattattgg gtatcgaact tcaaaagtaa
     1021 aagaagactg tgcgtatttg gaacggttgt ttaaagaacg tcagcaggaa tattatgctg
     1081 ctcaaagaaa atatgcggat tatgtagacg cccatgataa tgtggttctt caaagtgtac
     1141 gtgctgagca ggagcgttta cagaacgaca tgagtttggc ttatcagata tatagtcagg
     1201 ttgctaatca gttgcaggta tccagagcca aagtacagga ggaaaagcca gtctttgcag
     1261 tagttgagcc tgccgttgta cctttgaaac cttcaggtat gggactcaaa atttatattt
     1321 tattatttgt gttcctgtcc gtatctggta ctctcgtgtg ggtgtttttt ggcaaaagtc
     1381 tgctggctag cttgagaaaa gaactgaaaa ataaggagat agaacaggat aaatgatgct
     1441 aaaacgtcgt ttacaacatt cttacatcaa ttaaattcac ttactatatt attaaacgaa
     1501 tgatacgtac agctatgata atggctgcgg gcatgggaac ccgttttggc caatatacag
     1561 aattgatacc taaagggttc gtcaaagtgg gaggtattcc aatgatagtt cgttctattg
     1621 atactttgtt atcatgtgac attgagcgaa ttgtaatcgg tacaggatat aaacaagaag
     1681 tttatgaaga attgaagaca gactatccta tgcttgaaac ctgttttagt cctcgttatg
     1741 ctgaaacaaa tagtatgtat actttatata atacgcggga gattctgggc aatgatgatt
     1801 ttttattgtt agagtcagat ttgatttttg agaaacaagc aataatgagc ttattggagt
     1861 gtcctgcggc agatgcaatg ctaataactc cagtgacaaa gtttcaagat cagtattatg
     1921 tggaacatga tgataatttt cgcctttctt catgttctgt caataagaat aaactaaacg
     1981 ctaaaggcga attggtcggc atccataaac tatccggttc cttttacaaa ataatgtgtg
     2041 ctgattatgc gagtattgtt gatgaacaac ccaatttggg atatgagtat gaattactac
     2101 gaatatcttg ttctcaatct cctgtttatg tgcataaagt agaagggctg aaatggtatg
     2161 aaatcgatga catatcagat ttggaatatg cagagaaata tattgttccg tattgttaat
     2221 taaaataata tatcaaatta tgagtaagac agtttatatt gggatgactg cggatattat
     2281 gcatccagga cttatccgca ttattaatga ggctactaaa tacggtgatg ttataattgg
     2341 tcttcttaca gataaagcta ttgcggagca taaacgcctt ccttatctga cctatgaaca
     2401 acgaaaagag gtagttcaga atattaaagg cgtatgtaaa gttgttcctc aagaagaatg
     2461 gagctatgtt gagaatctca aacgcattaa acctgactat ataattcatg gtgacgactg
     2521 gaaaaccggg cctttacgtg aagaacgtgt gcgcgtattt gaagtgatga atgaacaggg
     2581 aggaaaggtt atcgaaattc catatacttt gggaattaat tcatcttctt tggataaaga
     2641 tattaaggct ataggtacaa cccctgatgt acgtttaaaa tcacttcgtc gtttgataaa
     2701 tgccaaaccc gtagttcgta ttttggaagc tcatgatgga ctatgtggct tgataattga
     2761 aaatcaggaa atattaaaag gggataagag ggaagtattt gacggaatgt ggtctagtag
     2821 ccttacggat tcaaccagta aaggtaaacc tgatattgag gcggttgatt taactacccg
     2881 attgcaagat ttgaataata ttctggagtg tactactaaa cctattattt ttgatggaga
     2941 tacaggtggt aaaattgaac atttcgtatt tacagtacgc actttagaac gtcatggaat
     3001 ttcagctata ataattgaag ataaagttgg attaaaaaag aattcattgt ttggtacaga
     3061 tgttattcaa actcaagata caatcgaagg tttctgtaat aagatcaaag caggaaaggc
     3121 atctcagatt actgatgatt ttatgattat cgctcgtatt gagagcctta tagcgggaaa
     3181 gccggtaagt gatgctttag agagagcttt tgcatatgtc caagcgggag cggacggtat
     3241 tatgatacat agcaaaaata agtcgggtga agatataaaa gaattttgtt tggcgtttcg
     3301 aaaacagtat gctcatgtac ctatcgtggt tgtgcctact acatatgatc atatttatga
     3361 gtctgaattg tgtgattggg gtgtgaatat aattatttat gctaatcata tgcttcgtgc
     3421 cgcttatcct gctatgatga atgtcgcaaa gataatatta gagaatgaac gtgctttaga
     3481 ggtgcgcgaa ctgtgtatgc ccataaaaga aatattggaa ctgattccag gtactaaata
     3541 aaaagaggaa tatcattatg ttaagcgtag aaaaagttta tgaaacgttt ctgagtcatg
     3601 acgttgattt ttttacagga gttccagact cattactaaa aaatatttgt gcctatatca
     3661 cagaccatac ttcacgtgag aaacatatca tagctgctaa tgaaggtgcg gctgtaggaa
     3721 ttgcttcagg ttattatatg gcatcaggta aggttcctgt ggtttatatg caaaattccg
     3781 gcttgggtaa tactgttaat cctctgctgt ctcttgcaga tgaacaagta tacagttttc
     3841 caatgctttt gatgattggc tggcgtggtg aaccgggaac aaaagatgaa cctcagcata
     3901 aaaaacaggg tgaggtaact ttagatttgt tgaaagcaat gcggattcct tatataattc
     3961 ttgattcaaa tgagaatgat gcatttattc agctccatga tatcatacaa tcagcaaaaa
     4021 ctaagaatat tcctcatgca ataattattc ggaaagatgt ttttggcaaa tataaacttc
     4081 aaaaagagtt cggatgtaat tatcctttat ctcgtgagga tgctttgcaa atagttgtgg
     4141 attatctgcc tgaaaattca gtggtcgttt ctactactgg caagctttct cgtgagttat
     4201 ttgaatatcg agaaatgaaa gagcaaggtc atgaacatga ttttctcacg gtaggctcta
     4261 tgggacatag ttcatcaatc tctttgggta ttgctatagc aaagcaagat agacctgttt
     4321 attgcttgga tggtgatgga gcatttatta tgcatttagg ggcaattagt aacattggcg
     4381 atttatctcc taaaaactat tatcatattt tgtttaacaa tggtgctcac gagtctgtag
     4441 gaggacagcc tactttagga tttagtttag atattccggc tattgtccgg gggagcggat
     4501 ataagcatac ttatactgtt tgtacaaaag ttgaaattga agaagcaatg aagcagcttc
     4561 caaagttatg tggtcctgtt ttgttggaaa taaaggttaa aatagattct cgggagaatt
     4621 tgggacgtcc cacgactact cctatagaga ataaggagca ttttatggat tttttaaaat
     4681 aaatatattc gatgaaaata gaaagaaaaa tattattaaa tcctgggcct gccactacta
     4741 ctgacagtgt aaaaatggca caagttgttc cggatatttg tcctcgcgag aaagaattcg
     4801 caggtatgat gaaacaactt cgggacgatt tggtcagagt tgctcatggg aatttggaaa
     4861 aacataccgc tgtattattt tgtggctcag gaaccatcaa tattgatata tgtctaaatt
     4921 ctcttcttcc tgaagacaaa agggtgctta tagtgaataa tggggcatat agtacccgtg
     4981 ctgtagaagt gtgtcaatat tatggtttgc ctcatattaa tttggaattt tccgtttacg
     5041 aacgtcctga tttatcggtg gtggaaaatg tgttgcaaga aaatcctgat atagctatgg
     5101 tttatactac tcatcacgag acgggtacag gaattctgaa ccctattcgc gagatgggcg
     5161 ctat
//
