LOCUS       c00405_gnlPro..        13853 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GJBBNPDD_405.
ACCESSION   c00405_gnlPro..
VERSION     c00405_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:51:13
            Original ID  :: gnl|Prokka|GJBBNPDD_405
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13853
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..291
                     /locus_tag="ctg405_1"
                     /transl_table=11
                     /translation="TRSIQVLSVCDNLNGHLKLGMYTTVHFLSVPVGQIQIPEKALLQG
                     EKDSYVFVQIAPLVFVRTSVTVETTENGIAVISEGLRPGDKIISEGGYYLK"
     protocluster    1..13853
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8402:13259]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8403..13259
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13853
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13853
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             298..3405
                     /locus_tag="ctg405_2"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVVLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITGFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTQEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSVTTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPAFYYLVENNVLNKKKNDEKEYTI"
     CDS             3383..4633
                     /locus_tag="ctg405_3"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPTFAQMPEIKQGQSISFEEYLNRV
                     GKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLFLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLETVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQTEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALERACGIWDICF"
     CDS             4970..5737
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg405_4"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.2e-08,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVSVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             6116..7885
                     /locus_tag="ctg405_5"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDTKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTGM
                     TPYEFKKTQESLG"
     CDS             7956..8318
                     /locus_tag="ctg405_6"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             8403..9635
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_7"
                     /sec_met_domain="HBT (E-value: 2e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             9632..10744
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg405_8"
                     /sec_met_domain="Chorismate_bind (E-value: 2.9e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             10764..12431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.4e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             12435..13259
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg405_10"
                     /sec_met_domain="ECH_1 (E-value: 1.9e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             13263..13853
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg405_11"
                     /sec_met_domain="MR_MLE_C (E-value: 5e-12, bitscore: 35.3,
                     seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLLNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQLEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEK"
ORIGIN
        1 acccggtcca ttcaggtact ttcggtctgt gataatttga acggacatct gaagctgggg
       61 atgtacacta ctgtccactt tctgagtgtt ccggtcggac aaattcaaat cccggagaaa
      121 gcgttactgc agggcgaaaa ggatagctat gtatttgtgc agattgctcc gttggttttc
      181 gtacggacgt cggtgacagt ggagacaaca gaaaacggaa tagcggtgat cagcgaagga
      241 ttgcgtcccg gagataagat aatcagtgaa ggaggatatt atttaaagta agaaattatg
      301 aagaaggaat taatgctttc aattatacaa aaaagatggg taatgctttg cctgtttgtg
      361 atgatgtgta tctttggata ttactcatgg aaacagcttt cgatagaagc atatccggat
      421 attgcagatg tcacttccca ggtggtcact caagttcccg gactggctgc ggaggaagtg
      481 gaacagcaga taaccattcc tttggaacgc gctattaatg ggctgcccgg tatgcacgtc
      541 atgcggagta agagtacatt cgggctgtca atgattacca ttgtctttaa ggacgggaca
      601 gaggactact ggagccgcca gcgcgtacag gaaagattga atgaagtaga actgccttat
      661 ggagctgttc cgggacttga tccgctgaca tctcccgtag gagaagtgta ccgttatatc
      721 atagaaagtg accagcactc attacgcgaa ttaaccgacc ttcagaactg ggtaattatt
      781 ccccgtatca aggaagtgtc gggagtggct gatgtaacca atttcggtgg gatcactact
      841 cagttccagg ttgaagtaga tccgtccaaa ctggaacaat ataatttatc tctcagccag
      901 gttgttgaag ccattgagaa taacaatgcc aatgtggggg gaagcgtgtt gaatcgtggt
      961 gacttgggtt atgtggtacg gggaattgga ttaatcggaa atttggacga tttgggacat
     1021 attgtagtga gtactacttc cggagttcct gtctttctga atgatatagg ttctttgaag
     1081 tatggaaatc ttgaaagaaa gggagtgctg ggatatacgg accgtacccg caactactct
     1141 gagagtctgg aaggaattgt actccttctg aaacatgaga atccgtctaa agtactggaa
     1201 gatattcatg tggcagttga tgagttaaat aatgagacat tgccggaagg agtgaggata
     1261 catacttttc tggatcgtac caacttggtg gatactactt tgagtaccgt atcccatacc
     1321 ttgctgatgg gtatggcttt ggtggttctt gtgcttattc tgtttctagg caactggcgt
     1381 ggtgcattat tggtatctat aacgattcct gtgtcattgc ttatcgcttt tattcttatg
     1441 catctgacgg atattccggc taaccttctg tcgcttggtg ctattgattt cggtattatt
     1501 gtggacggcg ctatcgttat gctggaaacg atccttaaga aacgtgagga taatcccaaa
     1561 caatatctcg aagaaaaaag catggcgcaa cgcgccaaag aagtgggtcg gcctattctt
     1621 ttctcaacca ttgtcattat tacggcatac cttccgctgt ttgcctttga acgtgttgaa
     1681 cgcaaacttt ttactccaat ggcatttacg atgagctatg caatgattgg agcactgttg
     1741 gttgcgctct tattgattcc gggacttgcc tatgcaatct atcgtaaacc acataaaata
     1801 tataagaata aatggctgga cagactaaag gataaataca ttcgtaccat tacaggattt
     1861 ctggaagctc ccttaaaagc catcattcca tcaggactga ttctgacagc ggggatcgtg
     1921 ttgagtgttg tcgtaggaaa agacttcctt ccggagctgg atgaaggttc gatatggtta
     1981 caggttaatc tgccacccgg aatttccgta gaaaagtcac gggagttatc tgatactttg
     2041 cgtgcccgta cgatgaagta ttccgaagta acttatatta tggtacaggc gggaaggaat
     2101 gacgacggaa ctgatccgtt caccccttca cattttgaag tgtccatcgg tattaagcct
     2161 tatgatgaat ggccgaaagg aaaaactaaa aaggatttga ttcatgaact ggaagaagaa
     2221 tataagttac ttcccggttt taaagtagga tttagccaac ctatgataga cggggtgatg
     2281 gataagatag ccggggccca tagtgaactg gtggtgaaag tatatggcga agattttcgt
     2341 gaaacacgtc gtattgccga agaaataacc agggcattag gaactgtgcg aggggctgtt
     2401 gatctggata ttgatcagga accacccttg ccacagttac agatcagtat gaatcgtgat
     2461 gccatagctc gttacggatt aaatgtatcc gatgtagcgg atctgattga agtggctgtc
     2521 ggaggtaaag ctatcgcaca actttatcag ggtgaccgcc agtatggcat cacctgtaag
     2581 tataaagagg aagcgcggaa tactcaggag aaaatagccg gacttatgtt gacttcttcc
     2641 accggtgcaa agatacctct ttctcaggtt gccgatgtca gattgagtgt cggcgaaagt
     2701 acgattacca gggaaatgaa cagacgccat ttgacggtaa agctgaattt gcgcggtcgt
     2761 gacctgacat cttttctgaa tgaagcccag aatacgatca atgagaaagt acattatgac
     2821 aagaataaat ataccatcaa atggggaggg gccttcgaaa atcaaaaacg ggcttataca
     2881 cgtcttgctg tcattatacc gctgacactg acagggatgt ttatactgct ttatgtcacg
     2941 ttcgggaagt tccggcaggc aggactggta ttggctattg ttcctctggc acttttcgga
     3001 ggtatgcttg ctcttaatgt gcggggaatg acgctgaatg tatcttctgc cgtaggattt
     3061 atagcgatgt tcgggctttc catacaaaat ggaattatca tggtatcgca ggtcaatggg
     3121 ctgcgcaggg gaggaatgga actccggaaa tcggtcatag aaggggcacg ccagcgtttc
     3181 cgacctattc tgatgacttc ggtcactacg atactcggac ttttcccggc ttcgttggca
     3241 accggaattg gtagtgacgt acagcgtccg ctggcaacag tgattgtgta tggattgatg
     3301 ttttcaaccc ttatctctat gtttctgctt ccggctttct attatctggt tgagaacaat
     3361 gttttaaata aaaagaagaa cgatgaaaaa gaatatacga tataatatag tgctcttgct
     3421 tttaatggtg gaagccgtac tcattccgac ttttgcgcaa atgcctgaaa taaagcaggg
     3481 gcagtctatt tctttcgaag aatatctgaa tcgggtaggg aaaaagaacc tgagttattt
     3541 agccgaaaaa ctcaatgtga gtattgctga tgcggaagta attgcccgga aaatctttcc
     3601 ggatccggag ttggaatttg aagcaggtaa tgagactttc tcgttgggag tttcctattc
     3661 attagaaatg ggaaataaaa ggggagcacg tattaagttg gcgcggactc aggcagaatt
     3721 ggagaaactg ttcctgcaac agggctttca ggatttgagg gcggaggctg ccgacctttt
     3781 tctagaagca attcttcagc gcgaattact tgaagtacag aaaagttctt atgagtatat
     3841 gtatcagctg agtcagtcag atagtttacg ttatgtttcg ggagagatta cggagaatga
     3901 tgtccggcag tcaaaactgg aaactgtcac cttgcttaat actgtttaca gtcaggaggc
     3961 ggcttatcat tccgctttgg ttttgttgaa taaacacatg gggatgagtg ctgatacgct
     4021 tcatatccct ttgggaaatt gggaagagct aagcagggac tttgctctgt ctgatttggt
     4081 caaagcggga ctggataatc gcatcgacct gcttgttgct caaaaaagta ctgaagttac
     4141 tacccgggaa tataaactga cgagagcgga acgcagaccc gatatcggag tatctgtttc
     4201 ttatgaaaga aactggaacg gctttcttcc tccgtcccgt tctgctactg ccggtgtatc
     4261 tgttcctctg acattctcga atataaataa aggagctgta aaagctgcaa agtttcggat
     4321 tgcccaatcg gagataatgg aaagagatat ggaattgcag atacagacag agataaccca
     4381 ggcctggttc aactatgagg ctgaaaagaa aaagatagct caatataaag ccggtgtact
     4441 tgaagactcg cagaaggtgc tcgacggaat ggtatataaa tacaaacggg gagaaacgag
     4501 tattcttgat gtactggttg cccagcgtac ttataatgaa gtgcaacagg agtatctgga
     4561 aacaatgaaa ggatatgccg cttcactagt agcattggaa agagcttgtg gtatatggga
     4621 tatatgcttt tgacagttaa atatccggct ttactattgt gaattgcagc aaagccggat
     4681 atttgtatgg ttaccagtca gcggtttcac gctttatgtt aaatcattgt gcgatattcc
     4741 tcctgttttt tcttagggag tttttttgat cacttcttcc acagagtggt caataagttc
     4801 tttgataagt ttgtcactca ggtttattta cttatctgtt ttccgaactt taatccgtac
     4861 tactgtgtca ttttgacgag actggacaat gttttattac tttcgattgt gtatctttgc
     4921 tgtagttgaa atggacaacc ggaatttata tactaataaa cagaatatta tggaagcgaa
     4981 gtatatcact ctgactaaag agaatatcga aaaagaacat atttgctgtg ctttctccga
     5041 taagaaatgt aaggatagct atgagttgaa aaagacatgg ctgaaaaatg agtttgagaa
     5101 tggctatgtt ttcagacggc ttgacgaacg tgcaaaagta tttatagaat atggacctgc
     5161 cgaaaaagct tgggttccgg ttaatgcacc taactattta atgataaact gtttttgggt
     5221 ttcaggaaaa tataaaggat gcgggcatgg caaagcacta ttgcagtctg ctgtcgagga
     5281 tgccaaagca cagggtaggg atggcttggt gactgtggtc ggtacctcta aatttcattt
     5341 tatgggtgat gcgaaatggt tattacgtca ggggtttgag acgatagaaa aactacccta
     5401 tggtttcagt cttttggctt tgaagataaa tccggcagct cctgatccgt cattcaatgg
     5461 aacagtatca agtggagaat gtgaggaaaa agaaggtgta gtcgtttatt atacacatcg
     5521 ttgtccgttt gcagagtttc atgtccgtaa ttctttagtg agtgtgactg agaacaaagg
     5581 tattccattg aagatagtca gattggaaac gatggcacaa gcacaaaatg cacctacacc
     5641 tgctactatc ttttctcttt tctataaagg aaagtttgta acgacggatt tgagtgcatg
     5701 tatggagcaa cggtttgata aagcgttggg attataatct ttcttattac agtatgtgtt
     5761 tctctttttt gattttctgt ttttgtgctg ttttgctctg atgagtgtgg cgggttaata
     5821 attgtctggt gtttatttag actggtcggt tcgatttttc atgtgctgct ctgatcttat
     5881 gcagattcat taatagaatc ggcagtttat ttatatgttg agatgttttg ttttatgtat
     5941 gtgacatatg cttgattttt agtattttat tgtatgtggt tggtggggaa aacttgatag
     6001 ctcctgactt ttataatcac taacttttct tattttagtt cattcaaata tgttcaattc
     6061 ttgcatttta tgaaactatg ttttactttt ggggagtaaa atcattggga ttataatgaa
     6121 aagtattcgc tcggttattt gtttttgttt gtttttgttt gtgtttaacc agctcctttt
     6181 cgccgacaaa actatagaga atgattcgct atataccagt gagtatataa gtcgaattta
     6241 tatggcagaa cctgaacggg ctttaagttt gttggatgga gctgaaagta agaagactat
     6301 ccctctgcgt attatacatg aattacgcag cagggtttat cgtaatatgt atatgactaa
     6361 actggctttt ttgtatgcca aaaagtctta tttgctggat tccgtttctc agaaagatac
     6421 taagcacttg ttgaccatga ctgtcgacct ggcagaatta gcagtgctta tgagtgacca
     6481 taaagagagt atgaggtatg ctcttgatgg tatcaagcta gcacaaaaag aaaaggataa
     6541 aggggctgaa agtaagctgt tgttttgcat tggtgaaaat aaatggcaat tgtctttcaa
     6601 agaggaggca tatgactatt ttgacaaagc tatcaaattg cttcaaggta caagttccaa
     6661 attggaaatg gctatgcttt catactttta tgggatgaaa atggattatc tgctcaatga
     6721 ttcccgtagt aaagaagcat tggaggttgg gttgaagcgc gaaaagctac ttaaagatat
     6781 agctaaatta ccggaaaaaa caaaaggctt tcttgatctg caatatactt acttgtatgc
     6841 aaaaatgtcg tatatctgct atctggaagg aaagtatgat caggcggaaa aatattatca
     6901 acaatatttg tcaacagaga attcacagac accggatgga aaaacctatg cgatacctta
     6961 tctgctagtg tctaaacaat atcagaaagt cgttgatcaa tgtcaggatt ttaagaaatt
     7021 gatgcaagag caggatactg tcaacttgca gtatattagt atccttcaga aagaggtgaa
     7081 agcttataaa ggcttgaagg attttgaaaa agtagcagca ttacgtgagt ctattatttc
     7141 tattattgat ggtattaaca gcaaggataa acagaatgcg gctttggaat taaatgctat
     7201 tcataaagct gacgagcagg aagaatatat tgccgaacag actttacagt taagaatcag
     7261 aaacatatca cttgcttttt tgggatgtgt cacttgtctc attttatttg tgctatggcg
     7321 gatttggcgt catacgatta ttgttaaata taaaaacaaa atgctggcaa agtttatcaa
     7381 tgagaaactg gctggaaaag tagagaacaa acaattattc atagatggag atgcggaaga
     7441 tccgatagct gttccattgg acttggaacc ggaaactggc ttttccgaaa aagacgattt
     7501 atctccggat gaagtagtgg agagtaggga ggaagaggat gagaataaga aaattttcaa
     7561 agaactgaat cgtattgttg ttcaggatca gttatatctg tctccggaat tgtcgagaga
     7621 ggatctggct cagattgtac atttgaataa tgcgcgtttc gcccggatga tcaaggaaaa
     7681 caccggaact aatttcaacg ggtatattaa tgaacttcgt attaactatg cgattcagtt
     7741 attgaagcaa catcccaatt ataccattcg tgcgatagct gatgaagccg gatttaatag
     7801 tacgcctatt ctgtacagta tgttcaagaa aaagactggt atgactcctt acgaatttaa
     7861 aaaaacgcag gaatccttag gttgattttg gctttttcga taaacaattt tccgttttat
     7921 cggtttattc ttatgataac taaatataaa cggaaatggt gcaagttagg ataaagcgag
     7981 tgtacgaaga cttttcagag accgacggat atcgggtgct ggtagataaa ctctggccac
     8041 gtggaatcaa aaaagaatgg ttgaaatatg attactgggc aaaagatata acgccttccg
     8101 cagcactgcg cagatggttt catgaagata ttccgggtca ctggaatgat tttgtcgtaa
     8161 tgtatcagaa ggaactggaa gcttctcaag ctgttgccga ttttctgact cttatcaaac
     8221 ctcatccggt gatcactttg ctttatgcat ccaaagaacc ggtttataat catgcccgaa
     8281 tccttcgtga ttatttggaa atgcatctga aagagtgaaa ttaaagtaat ttttatctct
     8341 ttccgctttc agtcgttcac tcaatttcct acctttgtaa tctaaatcaa aatcgtgtgt
     8401 ccatgaagta taaattatta gttcttgatg tagacggaac gcttctcaat gatgcaaaag
     8461 aaattagtaa acgtacattg gctgctttgc tgaaagttca gcagatggga gtacgtatcg
     8521 tgttggcatc cggccgaccg acttacggtc tgatgccttt agccaaatcc ctagaactcg
     8581 gaaattatgg aggttatatc ctttcttata atggttgcca gataattaat gctcaaaacg
     8641 gagaaatact gtttgagcgg aggattaatc cggaaatgtt gccttatctg gaaaagaagg
     8701 caagaaaaaa taatttcgca ctgttcactt accatgatga tacgatcatt actgacactc
     8761 cggagaatga acatatccag aatgaagctc gcttgaataa tttgaaagtg atcaaggaag
     8821 aggaattttc tgtagcaatt gactttgctc cgtgtaagtg tatgcttgtc agcgatgacg
     8881 aggaagcgtt ggttagtctg gaaggacact ggaagagacg gttgaacgga gctttggatg
     8941 ttttccgttc cgaaccttat tttctggaag tagtgccgtg tgcgattgat aaagccaaca
     9001 cattgggagc tttattggaa gaactggatg tgaagcgtga agaagtcatc gctataggag
     9061 acggtgtgtg cgatgtaacg atgattcagc tggcaggact gggagtggcg atggggcatt
     9121 cgcaggattc ggtaaaggtc tgtgcggatt atgtgacagc ttccaatgag gaagacggag
     9181 tggctctggc tgtcgaaaag gcgataatag cggaagttcg cgctgcagag attcctttgg
     9241 accagttgaa tgcacaggcg cgtcacgcat tgatgggtaa tctgggtatc caatatacat
     9301 atgccgacga agaccgtgta gaggcgacga tgccggtaga tcaccgtacc cgtcagccgt
     9361 tcggtatttt gcacggtgga gctacgcttg cattgggaga aacagttgcc ggactcggct
     9421 cgatgattct ctgtcagccg gatgaaattg tggtaggaat gcaggtcagc ggaaatcata
     9481 tatcttctgc gcacgaaggt gatacagtac gtgcagtagc gacgattgta cacaaaggac
     9541 gttcctccca tgtatggaat gtggacgttt ttacttcaac caataaactg gtgtcctcta
     9601 tacgggtggt caacagtgtg atgaaaaaaa gatgattgac gaaaaaagta acttgacaac
     9661 tattgatgca cttattcagc ggaaacagcc ctttgctgtt tatcgtgttc ccggggagaa
     9721 gtatcctcgt ctgttgacag aagatgtcgg agctgtccgc ttgattttcg atttgaaaga
     9781 actgaatgga caaagaggat ttgtgattgc tccgttccgt atagataagt catgtccgat
     9841 tgtgttgata cagtccgaca ggactggaca accgttgcct atggaaatcg tggcagagga
     9901 agagcaggac ttgcaaagtt atccggagga atcttttcat accctttgta ctgggaagta
     9961 tgcgacctgt tttcatacat ttattgaagc cttgcgtgat gctacctttg ataaactggt
    10021 gctttcccgt agtctcacta ttggaaagaa tccggagttt tccccttcag ctgtttttcg
    10081 tgcagcttgt caacgttata ttcattccta tatctatctg tgttatactc ctcagacggg
    10141 cgtgtggctg ggaagtaccc ccgaaattat attgtcgggc gaaaaaaatg aatggaacac
    10201 agttgccctg gcaggaactc aacctttgca gaatggtaaa cttccgcaag tatgggatga
    10261 caaaaaccgt caggagcagg attatgtggc gtcctatatc cgtcggcagc ttctttcgct
    10321 gggcattcgc tccacagaga gcggacctta tccggcttat gccggtgcct tgtcacatct
    10381 gaaaactgat ttccatttct ctttgaaaga taataaaaat ctgggagacc ttctgaaagt
    10441 cctgcatccg actcctgccg tgtgcggact gcctaaagaa gaagcctacc ggttcatttt
    10501 ggaaaatgaa gggtacgatc gtaagtatta ttccggtttt atcggttggc tcgatccgga
    10561 gggacgcaca gatttgtatg tgaatctgcg ttgcatgcac attgaagacg agcaattgac
    10621 actgtatgcc ggtggcggat tgttagcctc ttcagagttg aatgatgaat ggcaggaaac
    10681 ggaaaagaaa ttgcagacca tgaggcgtat tcttgtgtct gctccaataa tgatgaatca
    10741 ctaacaagct aatcactatc aatatgtatt cggacaagaa aaatatactc cagttggtcg
    10801 cgctgcttga ggcgcatgga attacgaaag tagtgttatg tcccggtagc cgtaatgcac
    10861 ctattgtgca tacgctgtct actcatccgg gttttacttg ttatgctatg acggatgaac
    10921 ggagtgccgg ttattttgcg attggtcttg cgctgaatgg cgggcatcct gctgccgttt
    10981 gctgtacttc cggtacagcg ttgctcaatc ttcatcctgc tgtggcagaa gcgtattatc
    11041 agaatatacc tttagttgtt atctctgccg atcggcctgc tgcctggatt ggacagatgg
    11101 cgggacagac attgccgcag cccggtgttt ttcagacatt ggtgaagaag tcggtaaacc
    11161 ttccggagat tcagacagaa gaggatgaat ggtactgtaa ccgcttggtg aatgaagcct
    11221 tgctggaaac caaccatcat ggaaaaggtc cggtacatat taatattcct atatccgaac
    11281 ctttgttcca gtttacggtg gagtcgcttc ccgaagtacg tgtcattacg cgctatcagg
    11341 ggctgaatgt atacgaccgg gattacaatg acctgatcga acgcttgaac agatatcaga
    11401 agcggatgat tattgtcgga cagatgaact tgatttactt gtttgagaaa cggcatacca
    11461 aattgttata taaacatttc gtgtggctga ccgagcatat cggtaatcag acagtacccg
    11521 gtattccagt gaagaatttt gatgcggcgc tttatgcgat gcccgaagag aaaaccggcc
    11581 agatgactcc cgagttattg attacttatg gcggacatgt ggtttccaag cggttgaaaa
    11641 aatatcttcg gcagcatccg cctaaagaac attggcatgt gtctgctgat ggagaagtgg
    11701 ttgaccttta cggttctctg actaccgtca tcgaaatgga cccgtttgag tttctggaga
    11761 aaatagctcc attgctggat aaccgcgtgc cggagtatcc ccgtgtatgg gagaattatt
    11821 gcaagaccat tcccgaaccg gagttcggat attcggaaat gtcggctatc ggtgctttga
    11881 taaaagcatt gccggaatca tgtgcattgc atctggcaaa tagttctgtt atccgctatg
    11941 ctcagttata ccaggttcct tctacgattg aggtatgctg taatcggggt acaagcggca
    12001 tcgaaggctc gttgtccacg gcagtgggat atgccgccgg ttcggataaa ctaaatttta
    12061 tagttatagg tgaccttagt ttcttttatg atatgaatgc tttgtggaac atcaatgtcc
    12121 gtcccaatct acgcattctt ttgctgaata acggaggagg ggagattttc catacattac
    12181 ccggactgga tatgtcgggt acatcgcaca agtatattac agccgttcac aagacatctg
    12241 ccaaaggatg ggcggaagaa cgcggattcc tttatcaacg ggtagagaat gaagaacagc
    12301 ttgccgaagc gatgaaaacc ttcacacaac cggaagccat ggaacaaccg gttctgatgg
    12361 aagtattcag caataaaaat aaagatgcac gtatactgaa agattattat catcaactaa
    12421 aacaaaaata gattatgtca acacaaagag aatggacaac catcagagaa tacgaagata
    12481 tcctctttga ttactataat gggattgccc gcatcaccat taaccgtgaa cgctatcgaa
    12541 atgcatttac tccgactaca acggctgaaa tgagtgacgc attgcgcatt tgccgggaag
    12601 aagcggatat tgatgtgatc gtgattacgg gagctggtga caaggctttc tgttcgggcg
    12661 gtgaccagaa tgtgaaaggg cgtggcggct atatcggcaa ggacggtgtt ccccgtctga
    12721 gtgttctgga tgtacagaaa caaatccgca gcattccgaa accggtaatt gctgccgtaa
    12781 atggatttgc cattggtggc ggacacgtgc ttcatgtagt ttgcgattta tcgattgctt
    12841 cggagaatgc gatcttcgga cagaccggtc ctcgcgtagg tagctttgat gcaggtttcg
    12901 gagcctctta tctggctcgt gtcgtcggtc agaagaaggc acgtgagata tggttccttt
    12961 gccggaaata caatgcgcag gaagcgttgg atatgggatt ggtgaataaa gtagttccat
    13021 tggagcaact ggaggatgag tatgtgcaat gggcggaaga aatgatgctg ctcagtccgt
    13081 tggccttgcg gatgattaaa gccggattga atgccgaact ggacggccag gcaggtattc
    13141 aggagctggc aggggatgcg accttgcttt actatctgac ggatgaggct caggaaggaa
    13201 agaatgcatt tctggagaaa cgtaaaccta actttaagaa atatccgaag ttcccttaaa
    13261 caatggattg caaaatagac attattccgc gggtgcttca tttcaagcag ccggccggaa
    13321 cttcacgagg cacatacaca acgcgaaaag tctggtatct tcattttact gctcccgaat
    13381 ttcccaattg ggtagggatc ggggagtgcg ctcctctgct aaatcttagc tgtgatgatc
    13441 ttcccgatta cgaggaagtg ctggctaaaa tctgccggca ggtagagaat cagggaggta
    13501 agctggacat ggaagctcta tgcaagtacc cttccatcct ttttggcttg gagacagcca
    13561 ttcgtcactt ttttgaagga agctgggctt tgtgggatac acccttctca cgtggggaag
    13621 caggtattcc gataaacggg cttatctgga tgggtgactt caatagaatg cttgctcagt
    13681 tagagaagaa gatggaggcg ggattccgct gtataaagtt gaagatcggt gccatcaact
    13741 ttgaagaaga actggcttta ctccaacata tccgctctca ctattcttct aaagaaatag
    13801 aattgcgtgt agatgccaac ggagcattct caccaacaga tgcgatggag aaa
//
