LOCUS       c00059_gnlPro..        16687 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHGKBCJL_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:06:59
            Original ID  :: gnl|Prokka|CHGKBCJL_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16687
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3217:6775](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3218..6775
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16687
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16687
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(645..1799)
                     /locus_tag="ctg59_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1979..3184
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3218..6775
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6900..7088
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7099..7959)
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7987..8817)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEAAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8814..10040)
                     /locus_tag="ctg59_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMCERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10513..11799
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQTLGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTTTDKILFWCCFVLLCIVPIDIFVPVPIRDLITKTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11762..12094)
                     /locus_tag="ctg59_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12122..14875)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15208..16434)
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 accaacaaaa gacaactaac ataggaataa gaataacaaa agtaaaccta tttagatatt
       61 aaagtatatt gagtaaacta attcagttat aacaaacgaa gttgtcaact aaaaccagta
      121 cacatcacca attccaattt agcagtatct tcaaagagtt tccattgctt gaaaccagag
      181 tttcatcggt gtgaaactgt agtttcatcg gtgagaaact agagtttcat acgcttgaaa
      241 ctttagttcc aaacgctcga aactatctga aactactgtt gatttgattg acttaaccgc
      301 atgttccaat cacattgaac gcatcagcta cttcaatagt actgctctct ctgaaaacat
      361 taaatcatat atcagtcaat aatacataaa ttatcagtcc ttaatacttg atttctcaat
      421 tattaatatc tgagaaatca aacgttaaca gttgagatat cagatattaa catcctgtaa
      481 atcaaagaat aacacagtaa aaacagtatt tatcaggacg atgcagagtg agagcaagtc
      541 cttgctctca ctctgctacc actggatctc taacagctaa aacatcgatg aataaaggga
      601 tacagacgaa ctgttagagc atgagagcaa aagcactatc tttttcactg ggggagagta
      661 agcaaaagaa acgcacgata ccggctttga ggcgtcaccg gtactaacgg caaatatccg
      721 gcacacaccc gattattctc tacggacaaa gggaacgaag ccgacatctg ccgatgttcc
      781 tccaaagcct gaccggctaa aggataataa tcaatccgaa aaactccttc cgcatccgca
      841 gccaaataac gatccgtcaa gagccatgcc accaccccca tattcattcg cagattaatt
      901 tcgacacaag gatgaatccg gtaaacaggc gcttcatccg gaaaatgaca aatcatcata
      961 tccactccca agtatccatg ataaaagcca ccgaacaaag ctgacaattc ttcttccaaa
     1021 cgagtccgca gcctgataaa ttcttcttgt ggcacataag ccgatagttt ctgcagaatc
     1081 ttctcgtcag acagcaagtc attccctgca tacatcccac tcccacccgt gtggaagacc
     1141 gaatatccgg caaaaacaac ccttcctctc ccgtcagcat aaaactccat agcgaaatct
     1201 tccaccttat tatatatagg ttcgcctacc accccaccct gagaagcagc gacacgggca
     1261 caccaaccgg aaataaaagt agtaaatatg cctttacacc aattcaatcc tttcccgctt
     1321 ccggaaagcg gagcttttaa caagcacgct tcccgccctt cgacgaacgc actgcactcc
     1381 gccaaagtac tcaaataaaa agattctcca cagaagtatt cattcaaccg caacccaggc
     1441 aacaacttta ccgcctgcag acgatgcgaa tgctctctca gaatattcat ataatccgca
     1501 gaaggcagct ccgtctgacc tgcccccaat gtcatcaaac gcttccgcaa agcagggtcc
     1561 caaccccacg gagagaactt ccagtcttta ccgtcagcca cttccggttc cgtcaacaag
     1621 gccacatcca tgcccaaaag ttcactcttt gttttcagga agtccgcatt ataagcagac
     1681 ggtgcaagca ccgcacttcc cgcttcggca taccacatag gaagcaacgc caggtcactc
     1741 gccatctgtc gggcggaagc cggcgccata tagttcgtct caccgcttgc caacgccata
     1801 tcatgctccg gattgaatat ataaacaggt cttttcgtca tgtcaaagat ggattcaaca
     1861 cattattctg caaatatata caggaaataa tcaggaactt acacaataaa gagaaactta
     1921 taaattaaag cacatttttg ctatctctac tttgcaaatc ctaaaaaaag cactatattt
     1981 gccagccgaa aaacaaagaa acgaaatgga atcattctat cgcacacacg cctacctcgt
     2041 tgagcacacc aatgcccccg ttcgccgcga tcttatggac gagatcgact ggagtgaccg
     2101 tctgattggt atcaaaggga cacgtggcgt aggaaaaacc actttcctcc tgcagtacgc
     2161 caaagagaaa ttcggcaccg accgttcctg tctgttcatc aatatgaaca acttttattt
     2221 ctccggtcac agccttgttg acttcgccaa cgagtttcag aaacgtggcg gaaaagtact
     2281 gctgatcgac caggtgttca aacatcccga atggagcaaa gagctacgaa tgtgctatga
     2341 ccgtttcccc agcctgaaga ttgtcttcac cggttcttcc gtcatgcgac tcaaagagga
     2401 aaacctcgaa ttgcgtgaca ttgcgaaaag ttataacctg cgcggattct ctttccgtga
     2461 atttctgaac ctgcagacag gaatgaaatt ccgggcatac agcctcgaag aaatcctcag
     2521 tacacatgaa cagatagcca aaggagtact ttccaaagta cgaccgctgg attattttca
     2581 ggattacctg catcatggtt tctacccttt cttccttgaa aaacgtaatt tctcggagaa
     2641 tctgctgaaa acaatgaaca tgatggtaga agtggatatc ttgctgatca aacaaattga
     2701 gctgaaatat ctttcaaaga taaaaaaatt actatatttg ttggctgtgg acggaccgaa
     2761 agctccgaac gtgagccaac tggcaagtga cgtacagaca tcccgcgcta cggtaatgaa
     2821 ctatatcaag tatctggcag acgcgcgtct gattaatctg gtttacccga aaggagaaga
     2881 attcccaaag aaaccgtcaa agattatgat gcacaactct aacctgatgt actccattta
     2941 tccggtgaaa gtggaagaac aggatgtact cgacacgttc ttcgttaaca ctttatggaa
     3001 agaccataag gtacataaag gagataaaaa cgtctctttc atggtagacg aagtgatgcc
     3061 gttcaaaatt tgtgcggaag gtacaaaaat aaagaataac ccggacgtga cgtatgcgtt
     3121 gcaaaaggcc gagataggcc gcggcaacca aatacctctt tggatgttcg gattcttata
     3181 ctaaaaagat ttatttactt aaatatttaa tttagttatg actaaacaga agaaattcat
     3241 cacatgtgat ggtaaccaag ctgcagcaca tatctcgtat atgttctctg aagtagcagc
     3301 tatctacccc atcactcctt cttcgactat ggctgagtac gtagacgaat gggctgccgc
     3361 aggacgtaag aacatcttcg gcgaaacagt attggtacag gaaatgcaat ctgaaggtgg
     3421 tgctgccggt gcagttcacg gttctcttca ggctggtgca ttgactacta cttacactgc
     3481 ttctcagggt cttcttttga tgatccctaa catgtacaag attgccggtg aattcttgcc
     3541 ttgtgtattc cacgtttctg ctcgtacact ggcttctcac gcattgtgta tcttcggtga
     3601 ccatcaggac gtaatgtcag ctcgtcaaac cggcttcgct atgttggcag aaggttctgt
     3661 acaggaagtt atggatttgg caggtgttgc tcatctggct actatcaaat cacgcgttcc
     3721 gttcatgaac ttcttcgatg gtttccgtac ttctcacgaa atccagaaga tcgaaatgtt
     3781 ggaaaacgac gacctcgctc cgctgatcga ccaggaagct ttggctgaat tccgtgcccg
     3841 tgcactgaat ccgatgaagc cggttgcccg tggtatggct gaaaaccccg accacttctt
     3901 ccaacatcgt gaatcatgca ataactacta tgaagcagtt cctgctatcg tagaagaata
     3961 catgaacgaa atttccaaga tcacaggccg caaatacggt ttgttcgatt actacggtgc
     4021 agaagatgca gaacgcgtaa ttatcgcaat gggttctgta actgaagctg cccgcgaagc
     4081 tatcgaccac ttggtagcaa acggcgaaaa agtaggtatg gttgccgtac acttgtatcg
     4141 tccgttctct gctaaacact tcctggctgc tgtacccaag actgcaaaga gcatcgcagt
     4201 gcttgaccgt acaaaagaac cgggtgctaa cggcgaacct ctttaccttg acgttaaaga
     4261 ctgcttctat ggcgcagaaa atgctcctgt tatcgttggc ggtcgctacg gtctgggttc
     4321 aaaagatacc actccggcac agatcatctc tgtattcgaa aacttggcta tgccaatgcc
     4381 gaagaaccac ttcactatcg gtatcgtaga cgacgttacg ttcacttctc ttcctcagaa
     4441 agaagaaatc gctctgggcg gtgaaggtat gttcgaagct aaattctacg gtctgggtgc
     4501 tgacggcaca gtaggtgcca acaagaactc tgttaagatt atcggtgaca acaccgacaa
     4561 acactgtcag gcttacttct cttacgactc caagaagtcg ggtggtttca cttgttctca
     4621 cttgcgtttc ggtgatactc cgatccgttc tacttacttg gtaaatactc cgaactttgt
     4681 tgcttgtcac gttcaggctt acctgcacat gtacgacgta acacgtggtt tgcgtaagaa
     4741 cggttctttc ttgctgaata ccatctggga aggcgaagaa ctggctaaga acctgcctaa
     4801 caaggtgaag aaatactttg cacagaacaa catctctgta tactatatca acgcaactca
     4861 gattgcaatg gaaattggtt tgggcaaccg taccaataca atccttcagt ctgcattctt
     4921 ccgtatcaca ggcgtaatcc ctgtagatca agctgttgaa cagatgaaga aattcatcgt
     4981 taagtcttac ggcaagaagg gtgaagacgt tgttaacaag aactacgctg ctgtagaccg
     5041 cggtggtgaa tacaagactc tgactgtcga tcctgcttgg gctaacctgc cggatgatgc
     5101 aaaagcagaa aacaatgatc ctgctttcat caacgaagta gttcgtccga tcaatgcaca
     5161 ggacggtgac ttgctgccgg tatctgcatt caagggtatc gaagacggta cttggtatca
     5221 aggtacttcc aaatacgaaa aacgtggtgt agctgcattc gttcccgaat ggaatgctga
     5281 aaactgtatt cagtgtaaca agtgtgctta cgtttgtcct cacgcttcta tccgtccgtt
     5341 cgtactcgat gctgaagagc agaagggtgc taagttcgag caactgaaag ctgtaggtaa
     5401 agcattcgat ggtatgacat tccgtattca ggtagacgtt ctcgactgtc tgggttgcgg
     5461 taactgtgcc gacatctgtc cgggtaatcc gaagaagggt ggcaaggcat tgaccatgaa
     5521 acaccttgaa agccagttgg ccgaagctga taactggact tactgcgctg aaaacgtgaa
     5581 gagcaaacaa cacctggtag acatcaaggc taacgtgaag aactctcagt tcgcaactcc
     5641 gttgtttgag ttctcaggcg cttgctccgg ttgtggtgaa actccgtacg tgaaactgat
     5701 ttctcagttg ttcggtgacc gtgaaatggt tgctaacgct acaggatgtt cttctatcta
     5761 ctccggttca gttccttcta ctccgtacac tatgaacgaa aagggtcacg gtcctgcatg
     5821 ggctaactcc ttgttcgaag acttctgtga atttggtctg ggtatggaac tggctaacga
     5881 aaagatgcgt gcccgtctgg tgaaagtaat gaacgaagct atcgcttctg attgctgccc
     5941 ggctgaatac aaagaagtat ttgctgaatg gatcaacaat atgctggatg cagaaaagac
     6001 taaggaactg gccgaaaaga tcattccgat ggtagaagct gctaaagata aatgcaacca
     6061 ctgcaagcaa atcgctgatc tgcaacaata tcttgttaaa cgcagccaat ggatcatcgg
     6121 tggtgacggt gcttcttatg atatcggtta cggtggtctt gaccatgtaa tcgcttccgg
     6181 taaggacgtt aacatccttg tattggatac tgaggtttac tctaacacag gtggtcagtc
     6241 ttctaaagct actccggtag gcgctatcgc taagtttgct gctgcaggta agcgtgtacg
     6301 taagaaagac ctcggtctga tggctactac ttacggttat gtatatgttg ctcagattgc
     6361 tatgggtgct gaccaggctc agactctgaa agctatccgt gaagctgaag catatccggg
     6421 accatcactg atcatcgctt acgctccatg tatcaaccac ggtctgaaag ccggtatggg
     6481 taagagccag gaagaagaag aaaaggctgt taagtgcggt tactggcact tgtggcgtta
     6541 caaccctgct ttggaagaag aaggcaagaa tccgttccaa ctggatagca aagaacctaa
     6601 ctgggaagac ttccaaggtt tcttgaaggg tgaagttcgt tacgcttctg taatgaaaca
     6661 atatcctgct gaagctgaag aactgtttaa agctgctgaa gaaaacgcta aatggcgtta
     6721 caacagctac aaacgtcttg ccagagaaaa ctggggagct gatacagctg aataataagt
     6781 agaaatactt tatacataat aaaaggcagg aatcctggaa acagattcct gccttttttg
     6841 tttatatctt agaagtaacg attacttctc acgaagatat tcattaaaac tctaaagata
     6901 tgatcggatt tgttatttgg attatcggtt tgatactgac tttcagagct gccatagaga
     6961 tttggaatat aaatgcggct gtagagaaaa gacttatagc gattgtatta atcgttctta
     7021 ccagctggct gggactactt ttctactact tctatggtaa agaaagaatg gcaggatggt
     7081 tgaagtagtg tttgcatatc aatctttctc aggaatccaa ctgtttacca gttcctgatg
     7141 ttcttccatc cattgacggg cagcctgtct ttccgttgtc tgcgcctctt ccagagcagt
     7201 cattaaagag ctgatttccg catctgtcag acgaatgttg cccaaaagtt cggcagcaaa
     7261 agggtctttc tcgctaaaac ctttccatgc tatggtatga atggattccg tatttccata
     7321 tatcagcttc gggtcctgaa gaactttcag cttgaaacgg tcgaacatcc agtgaggcgt
     7381 ccatcccgtc acgacaatcc agtctttctt atcaatcgct ttctttaggg aagcagtcat
     7441 ggcaggtccg ctcgaagtca tcagtttata atccaatcca tagtctttga tggcctgatc
     7501 ggtagctttc ataataccgg ctccggcatc aataccgaca atctgaccgg agaaacgttc
     7561 cttttccgcg ttcagttctt cgattgagtt gatcgtaacg taatccggaa tcaccagccc
     7621 gatacgggca ccatcataaa tatccccgat aacttcgagt ttatccccgt attgtttcat
     7681 ataatcttcc atagtgacag gcatccagac atccataaat acgtctgctt tcttacggga
     7741 gatagaggta aatataggtg caaggtcggc attcagcaac tttacatcgt acccctgatc
     7801 ttcaaaaatc gctttggcaa ggtttgtcat tgcaatacct tccgaccagt tggcataagc
     7861 gatacttatc ttcttactct ttccgttgtc tccgcaggaa acgaaggtta agagtatgcc
     7921 ggcaataaac attgccgcaa tcatttttat cttattcatt gattattcct ttctttggtg
     7981 tgattcttat ttctttttac tttttctgtt atctgccata ccctgagtga tgcggtccag
     8041 cacgatcgcc aatatcacga ctgcgatacc gccttcaaat ccgagtccga ttttcatttg
     8101 ggtgatacct ttcagcacga tttctcccaa tcctccggca gaaatcatgg cagcaatcac
     8161 taccatcgaa agtgacatca tgatcgtctg gttgattccc gtcagaatag taggcaacgc
     8221 caaaggcaat tgcaccttat aaagaagctg ccagggagta gctccaaaag agcgggaggc
     8281 ttctactacg tttttaggaa cctgacgaat gcccagaccg gtcagacgaa ccacaggagg
     8341 cattgcaaag atgatggtgg caaaagctcc cggcacagtt cccaatccga agaatagaac
     8401 ggcaggaatc agatagacaa aggcaggcat tgtctgcata aagtcgagga cagggcgcat
     8461 tatcttgtta caacgatcac tgttggcagt ccagattccc agcggaacgc ctaaaagcaa
     8521 tgccagacaa gtggaagaaa gtactaacgc caatgtctgc atcgtttctt cccaaaagcc
     8581 catgccgtaa ataagcaata aacccaagag ggtaaatacg gctgtcccct tacccgactt
     8641 aaaccaggcg agcgcagcca gcactgcaat tgtgatataa aaaggtattc caaacagtac
     8701 atgctgaaaa ccgtctatga atcctccgat ccccatgctg agagcatcaa aaaaggaagc
     8761 aaaatgttct gtgagccaat taatggcagc ctctatatat tgtccgatat ttatcataat
     8821 tctattgcgt tttgaatgat ttcattaatt tcttctttat cttttcccgt tacttcgatg
     8881 atcaatgagg aaagtggcac tacgccttca aactcccgat tctcatttac gacccagatt
     8941 ggcgagttcg tttttgtcat caacggaaga atatcttcca gcaccgtatc ccccagcact
     9001 gaatgaactt catgccttac tacggactcg atggagcgga tttgctcttt tcgtagtttc
     9061 agcaagtcat tcaaccgcac ctctcctact aacagattat tggaatcgac taccggaaga
     9121 acggtcagat tccgttcgca catcttacgg atcagcacct ccgggccttc tttcttcaaa
     9181 cgtgccacta tgggtttatc taccataaca gaggaagctg ttataatctt acttcgatct
     9241 acattctcca caaatcgttc tacataagcg ttggcaggtt cggtcaggat ttcttccgat
     9301 gtaccgattt gtacaatttc tccatccttc atgatagcaa tccggtcacc caatttaatc
     9361 gcttcactca ggtcgtgagt aataaagaca atcgtttttt tcatcttcga ctgcaaagtc
     9421 agcagttcat cctgcatctg cacacggatc aaaggatcga gtgccgagaa ggcctcatcc
     9481 atcaacagga cttcgggatt attggccaaa gcccgcgcca gcccgacacg ctgctgcatc
     9541 ccacccgaca gttcacttac catctgattc tcgtagcctt tcagccccac cagttgcata
     9601 ctttccatcg ctttctgctc ccgttctccc ttttttactc cctgtagttc gagcccgaaa
     9661 gctatattat gcaagacaga acggtgagga agcagaccga agttctgaaa gaccatagcc
     9721 agttctttcc ggcgaatctg caacagttct ttatccgaca ctttggctat gtctgttcca
     9781 ttgataatca cttctccgga agtagggcgt atcaaacggt tgatgcagcg gagtaaagtg
     9841 gactttccac taccggacag ccccataatg acgaatattt cgccttcatt aatggaaaga
     9901 ttcgcatctt tcaccgcaac tgtacatccg gtcgctttca atatttcact ttttgtttta
     9961 ccttctttca acatcttcaa agccttctgc ttctcattgc caaaaaccag atagagatct
    10021 ttaatttcta ttttactcat acaataaaat ggtttaggtt attaaaataa tatacacagc
    10081 aagacaagaa caaacgataa caggaatctt tctttatatc gtataaagtt ctgatttaaa
    10141 tacgggacaa ataacaatga atcccgaaat aattaataaa atgattattg acagactgag
    10201 taattaaaaa aggaatcgaa tttgataaga taatcctttc aacgaatagc aaaaaatagc
    10261 atttttatgt ataaaaacag cctgttccag tatcttgctg gcacaaagat acaaaaaacg
    10321 gattaaacat acaaattata ttcaaaatcc ggggcataca gagggcttta tttgtaatga
    10381 tatggaaagt ttccgggtaa tattccccta tcactcagca aaatagaaca aaccggcaga
    10441 taaatataaa ataagtttga atatttcact taaacaccgt atatttggcg tcaataacta
    10501 aactagattt atatgttcaa cagggctatt acaattttcc tggggaagga taattgtcat
    10561 tacacaacaa aagaaaaaca aacaggtact gccacactag acgacaaaag ccaagtacag
    10621 ttccttagta aaaagaaccc caaaatgccg tttttctata gccggcggaa tctctacatg
    10681 ataggtttcc tgctcgcttt tatagtgact ctgctcgaat ttatacgagg acggcatcaa
    10741 aactttatgg tcttctcgga cgctactcaa ttcttctggc aaggcatcag cccatacaca
    10801 actgaatttg tagaagctca cggacgctac ttcctttatt ctccagtttt cacggtattg
    10861 ttcgctccgt ttgcgtatct gcctgcatgg ctgggacctt tcgcgtggaa tctattcaat
    10921 tattcgctgt tctttatggc gatcttcacg ctgccccaac aattcaccca gcagcagaaa
    10981 tgccgtatgt tcctttttct gttactgatt ttaggacaaa gtttactttc atttcagtat
    11041 aacataacgg tagcctattt attcttattc gcctatacgt tattggaaaa agaccgtgga
    11101 tttctggctg ttctgttaat catgatttcg ggatgtacca aagtatatgg aattttcgaa
    11161 ctggcattgt tgctgtgcta tcctcacgta tggcgtaact ttggctatgc cgttacaatg
    11221 ggcattgtat tgcttgcatt accgttaatc aaaatagctc ctgcagattt gctcccctat
    11281 tatgaagaat ggtgccatag tcttgctgtt catcagtccg ccggagctta tgattcattt
    11341 ttctatgccc gccccattgc agcatggaca ttaccacact tccgtgcact tcagatagga
    11401 atgctcggct tgctgactct gctctttttg gggaatttcc gcaaatggtc gtcttttgcc
    11461 ttccgtgccc agactttggg cattctcatg ggctgggtag tattactgag tgactccgcc
    11521 gaaaaacata cctatattat cgcattggca ggtttcatgc tctggtattg gagcaggcca
    11581 acacgtacca caacagacaa gattctattt tggtgctgtt ttgtgctgtt atgtatcgtt
    11641 cctatcgaca tattcgtccc tgtacccatc agagatctca ttaccaagac cttatggctt
    11701 catgtatggg ttttctttat tgtatggata cggatgatat ggcttacctt ccttgcatcc
    11761 ttcattcatc cacgtgccac aaatgttctt tcagattaac gcatccgtta gctttgaaag
    11821 aaacttcttc tgccagcaag agttgttttt gttccaccca accgggcacc agccttccgg
    11881 tggaatttac aactctatgg cagggaatgg ataattcatc cggcacttct ttcaatgcac
    11941 gtcccaccat ccgcgagcat tggggtgccc ccaacagcaa agcaatacct ccataagtag
    12001 atacttttcc cacaggtatc tgggatacga cttcgtacac ttccttccga aaggattcag
    12061 aaaagctctc tttatctact ttataatctt tcatatatcc ctctttacga tcacaatgaa
    12121 atcatccttt ccttttcagg aaatctgtcg ggctctctcc aaactgctct ttatagcact
    12181 tggcgaaata agaaggtgaa ctgaaaccga cttcataacc aatctccgct acggtcatgt
    12241 ccgaagaagc aagcaaagaa gctgccttct tcaaacgggc gatacggagc aattcattcg
    12301 gagagtagtt agtcaatgat ttaatcttgc ggtaaagctg cacacggctt agtcccatgt
    12361 ctttgcccaa gtcctccaca ttcaaaccgg agtctcccat tttctcttca atcaatgact
    12421 tgaatctttc tacaaaatcc ttgtccatat cgcagacatc ttcttttgcc aatgtctgcc
    12481 cgtcaccaaa gaactgtttc agacgacggt gagaatcgat cagattgcgg acacgtgcca
    12541 gcaacagctg tgaactgaac ggctttgaaa tataagaatc cgcaccaccg tcatatccct
    12601 gaatacgctg ttcgtccagt gaacacgctg tcagcagaat aaccggaata tgacaggtct
    12661 gtaactcact tttcagccgg cggcaacatt caatgccatc aatgcccggc atcatcacat
    12721 cagaaatgat caggtccgga acatacttca tagccttacg gattccttcg gagccgtctg
    12781 ccgcttcaat caccgtatag tctgtatgca acagcgtatg gacatacgaa cggatatcct
    12841 cattatcatc aataatcagt acggacggtt tggaagagtc atatcctttt tccagttctt
    12901 cctcttccgc caatagaaca tctgttgtac gggaatccgc agaaacaagg gtggtatccg
    12961 gctcggcagc aacagcctca caagactgta caggcagttc aacggtaaag accgtgccct
    13021 gtttctcatc gctctctacg gagatcatac caccgtgcat ttctacgaag gcttttacca
    13081 atgccagtcc gattcccgaa ccggtatggt gcatatcgat cttatagaaa cggtcgaata
    13141 cattgcgaat atgttcggca gaaatcatag aaccggtatt tgccaccgtg aaacgtatcc
    13201 atcgcttgtc ctctttacta agggaagaca gacggacggc tattttcccg ttttccggtg
    13261 taaacttaaa ggcattggac agaagattga aataaatacg ttccagcttc tccatgtctg
    13321 ccagtgtatg ataatccgta tccggcatac tatcaaaaga aaaatggata tgcttcttac
    13381 gggctgccgc ctgaaaagac tcattccatc cttcgaaaga agaaaggaca tccaccgtaa
    13441 ccggagtata ttccatcttg ccgttttcat atttacggaa atccagaatc tgattgacca
    13501 gacgcagaag aatgttcaca tttcgctgaa tcagcatgag catccggtgc tgatctccac
    13561 tcaatgtctt gtccgccaat aaatgttcta ctgggtcggc aaccaatgtc aacggagtac
    13621 ggaagtcgtg agaaatattg gtgaagaata ccagcttggc atgagtagct tcttccagtt
    13681 gatgagaaag ttgtatcaat tggtcacgct gttcttccag tttgtcacgc tgctcttcca
    13741 attgctgctt ctgcttaaaa agctctttat tcaagcgatt cttagagcgg agtgatttat
    13801 aaacgaccaa taataagccg gctaccaata aaaggataat cagactgccg tataaaacta
    13861 cctgttgtgt agctacctga gagaggtatc caccgatacg tccgttgagc gtttcaatct
    13921 ttttatcgag ttcggaaatg tgtgtggtct gcaactgcat gacgtgtgcg ttggtacggt
    13981 ccacaacagc ggtattcatc accgtttctt tgggataggg tttcttctcc agaatgtcca
    14041 tagccagttg cagtacctta tcgccattgg tcggatagat aaaggtggca tccagcacac
    14101 tgtccagtac cagttccagt ccgtttccct tacccggcaa ggcatctatg ccgacaaaaa
    14161 tcatttcctt ctcccgccct gccatctttg ctgcctgata ggcacccgga gcgatacggt
    14221 cattatgggc atacacagca tcaatcttag gatgcctccg aagcatacta tccatttcta
    14281 tctctgccgg accacgttcc cacgcagcat ccgctttatc aatcagcttt atatccggga
    14341 atttactgat ggcagccata aatccctgat gccgttccat tgcaggagtc gaaccgctca
    14401 atcctgtcag ttctactata tttcccttcc cttttagact ggaggcaata tagtttccta
    14461 ccgaacgacc gatttcataa ttatcggctc cgatataggc agtatattta tccgaaagaa
    14521 tcttccggtc tacaagaata acggggatgc ctttctgata agcttcttct acaatcggag
    14581 tcataggagc agcttcgtta gcggaaataa tcagcagatc gactccttcg tccataaaat
    14641 aatggacatc ttccgcctgc ttactgttat catcccctgc cgaacggatt tccaccgaaa
    14701 caccattata aaacatcgct tcccgaagaa tctcatcatt catcttatgt cgccatgaat
    14761 catcgctgca ttgagccacc ccaatacgaa aacggggtgt atcctgccgg caagccgtca
    14821 tcccgattaa accaaacagc accagcatcc acttcagata tctcatcgtc ttcatccatc
    14881 tcatcatttc atagttcttt ctgtaatcca attaagaaca aaaataagaa ataatactgt
    14941 aaagttctct aacttcagct atttattatt ctaaaaagaa ggaaagcagt cctctttcag
    15001 accatcggaa agtattaaca aaagtataaa gcgtaaaaca aacacttaat caatgttata
    15061 aaacatagcg ttttacttgg ataatttgca gatttcacag aagtccgtat ctttgtactg
    15121 tgtttttcat agtattagat ttaaggttaa caaaggttgg agcaaggcgt tgctcctttt
    15181 tttatgccct gacctttcat ctaccgatta gttttcatcc cattcctttt ccagtttacc
    15241 atcaatagtg tagcgtttcc atcgtcctac acgacgacca ttcttatatt ccccacattc
    15301 acgaagctgg tcattcttta cataacgagc ttcgaacggt ccgttctgcc ttccgttcac
    15361 ataggtagaa gtttcccaat aatcaaagcg gttgctcact atcagccgtc gttccttgcc
    15421 atgcaatctg ccggcctgat aggtagcttc atatctcaat tcaccatttt ccaaattata
    15481 ttcacggtat aaaccgtctt tacgatcgtt cttcatataa tattctttct gccttacccc
    15541 acttccgttg gcaaatgaga catggagtcc atcttctttt ccatccagat aggtttcaat
    15601 catcagcgta tctccgcttt cagcaaaagt agtccaacga ccattcttct ttccattctt
    15661 ataactaccc agtatacgtg gcgagccaaa cgtaaacacg gacgaatatt caccgtcctg
    15721 aaaaccttct tcattgaaat aaacggtctc atacaaatca tatgtacctt tcagaaaagt
    15781 atactgtttg cctacctgct tcccgtcctt gtaattatgc tctttccgca aagtaccgtc
    15841 agattcgtac gacagttgct tcccgtgctc tttccccatc cggaagtttc tttcactttc
    15901 cacttttccg gtagtaaagt aacttttgct cgtaccgtcc agcttacctt ccttatagga
    15961 cttttcttct ttcagcttac cgtcaaactt ggagttaatc ttgaagaggc catccttccg
    16021 cccttcttta taacttcctt ccgttattaa tatattgtcc acatattctt tgtatccgcc
    16081 atcataaaaa ccatctttaa aagatgccag cacataggcg gaatgataac catctatgat
    16141 gcgatgttcg ccattcaatg ctttttccgt tttcagttcc tgaaacaaca gtctgccatc
    16201 gcctacatta acaacagata cctgatcgat cttatattcc ttttgcgcaa acaaaggaag
    16261 agcaagatat aaaaacaaaa atacgttcca gctttttgat ctgaggaagt tcgaaatgtg
    16321 tttcataaag tagttttctc tttttgattt attatttaaa aacctgccgc aaagataggc
    16381 aatcggctta taaaacaagg caagaaagag ggggacaatt agaaaaaaga acatctgtta
    16441 ttatcattct aataattaac agattaagta gtaaatcaaa acacagggaa gggggacatt
    16501 tactgaaata agaaacagaa aagaagatgt gtcaaaagca actaaattcc cctccttcag
    16561 gaaggaggag agtttagttg cttttgacac atttacattt gcagtattaa atatcacaac
    16621 aaaatataag tgtatatttg aaaagtagag ttgcagtgaa ctaactttga cactagtctt
    16681 aaatgac
//
