LOCUS       c00027_gnlPro..        15730 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOFMBKMH_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:08:06
            Original ID  :: gnl|Prokka|NOFMBKMH_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15730
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15730
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[479:5730]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      480..5730
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15730
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15730
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             48..473
                     /locus_tag="ctg27_1"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDITDAAADSYQTGERVMVIGETSMGMMAVALAFIIPFVLLIVSLFVLMALIGNEL
                     YAALLSLAVLIPYYFILWLNKTRMKQHFSFTIKPINN"
     CDS             480..1433
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_2"
                     /sec_met_domain="Fer4_7 (E-value: 4.8e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.2e-08, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.5e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 4.3e-08, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1e-10, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKPAAVSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             1458..2795
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_3"
                     /sec_met_domain="Fer4_10 (E-value: 4.9e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.9e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 8.7e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.9e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             2801..3793
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6e-120, bitscore:
                     391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             3820..4536
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_5"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             4551..5135
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.9e-70, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             5158..5730
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 8.2e-63, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5954..6988
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-51, bitscore:
                     167.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             7312..7611
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             7622..7984
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(8017..8847)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_11"
                     /sec_met_domain="GHMP_kinases_C (E-value: 2e-10, bitscore:
                     32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2.6e-10,
                     bitscore: 32.2, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFILKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             9086..10645
                     /locus_tag="ctg27_12"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             10817..13279
                     /locus_tag="ctg27_13"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             13311..14045
                     /locus_tag="ctg27_14"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             14055..14300
                     /locus_tag="ctg27_15"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
ORIGIN
        1 caaataatga ttaaatttgc cgcgatttgt aatgttgagt ttgcaaaatg acgaataata
       61 ctataaagca tctgggtatt gtggaaaaca tacagggttc tcatctgtcg gtgaggatcg
      121 ttcagacgtc ggcttgtgcg gcttgtagcg caaaaggtca ctgttcttcg gcggatagta
      181 aagacaaaat catagatata acagatgctg cggctgattc ctatcagaca ggagagcggg
      241 tgatggtgat cggcgaaacg tcgatgggca tgatggctgt agcattggca ttcataattc
      301 cttttgtact tctgattgtt tctctgttcg tcttgatggc gttgataggg aatgaactgt
      361 atgcggctct tctttctctg gccgttctta taccttatta tttcatttta tggctcaata
      421 aaacgcgaat gaaacaacat ttttcattta ctataaaacc aataaataac tagaacatta
      481 tgaatttgat tctgattgca gtgatttcat tgggagctat agcgctcgtg ctggccgcta
      541 ttctttatgt ggcttccaag aaatttgccg tgtatgaaga cccgcggatt gcccaggtgg
      601 gagaagtgct tccccaggct aattgtggtg gatgtggcta tcccggttgt agcggctttg
      661 ccgacgcttg cgtcaaagcc ggttcgctgg atggtaaatt ctgccccgta ggcggacagc
      721 ctgtcatggc acaaattgct gatatcctag ggcttgcagc cggagaagct gaaccgatgg
      781 tagcagtggt aagatgtaac ggaacgtgta tgaatcgtcc gcgtattaat cagtacgacg
      841 gtgcgaagag ttgcgctatt gccgcttcgc tctatggtgg ggaaacgggt tgtagttacg
      901 gatgtctggg gtgtggtgac tgtgtggctg cctgccagtt cgatgccatc cacatgaatc
      961 ctgaaacagg acttccggaa gtggatgaag cgaaatgtac cgcttgcggt gcctgtgtga
     1021 aggcttgtcc gaaggcgatc atcgaaatcc gtccgcaagg aaagaaatca cgccgtgtgt
     1081 atatctcttg tgtgaataaa gacaagggag ctgtggcacg caaggcttgt acggtgagtt
     1141 gtatcggctg tggcaaatgc gtgaagactt gtccgttcga agctatcacg ttggagaaca
     1201 acttggctta catcgatccg cacaagtgca aatcttgccg gaaatgtgtg gaagtctgtc
     1261 cgcagaatac cattatcgaa ttgaatttcc cgccgaggaa accgaaagaa gaagctccgg
     1321 ctgctccaaa accggctgct gtttctaaag aagcggtgga aactcctgca ccggcggcaa
     1381 aagtggaaac tcctgctgaa aaggctacag aagctccgaa agtaacagaa taataacaga
     1441 ataaaataca gaactgtatg ttaaagacat tttcaattgg tggagttcat ccacacgaaa
     1501 ataaattgtc ggcacatcaa cctattatca cagcggaagt tcctgcaaag gctgttattt
     1561 tgctggggca gcacattggt gcgcctgcaa aaccggttgt agcgaaaggg gatgtggtaa
     1621 aggtaggcac taaaattgct gaacctgccg gctttgtttc ggcagcaatt cactcttcgg
     1681 tcagtggtaa agtggcgaag attgatacta ttgtcgatgc cagcggttat gcgaaacctg
     1741 ctatctttat cgatgtggaa ggcgacgaat gggaagaaac aatcgaccgt agcgccacac
     1801 tggtgaagga atgtgaactt ccggcagaag agatcgtgaa gaaaattgcc gatgccggaa
     1861 tcgttggtct gggcggtgct tgtttcccta cacaggtgaa actttgtcct cctccttctt
     1921 ttaaggctga atgtgtgatt atcaatgctg tagagtgtga accttatttg actgccgacc
     1981 atcagctgat gctggaacac gcggaagaaa tcatggtagg cgtttctatc ctgatgaaag
     2041 cggtgaaagt gaacaaggca tttatcggaa tcgaaaataa taagcccgat gctatcgaac
     2101 tgatgactaa agtagcttcc agctatgcag gcatcgaagt cgttcccttg aaggtgaaat
     2161 atccgcaagg aggtgaaaag cagctgatcg atgcgatcac caaacgtcag gtggcgagcg
     2221 gtgcgttgcc tatctctacg ggagcagtcg tgcaaaacgt gggaacggcg tttgccgttt
     2281 atgaagctgt gcagaagaat aaaccgttgt ttgaacgggt gattaccgtg acgggaaagt
     2341 cggttgcgaa gccgtccaac ttcctggccc gtatcggtac accgatgaaa cagttgattg
     2401 acgcttgcgg tggtctgccc gaagatacgg gtaaggtgat cggtggcggt ccgatgatgg
     2461 gtaaggcgct cgtaaatatc gaggttccta ctgcgaaggg cagttccggc atcctgatta
     2521 tgaaccggaa ggaagccaaa cgtggtgaag ctcaaacctg catccgttgc gcaaagtgcg
     2581 tgagtgcctg tccgatggga ctggaaccgt acttactcgg agccttgtct gaaaacggag
     2641 attttgaaac aatggaaaaa gaaagaatca tggattgtat tgagtgcggc tcttgccagt
     2701 tcacttgtcc tgccaaccgt ccgctgctcg actattgtcg tctgggtaaa ggcaaagtag
     2761 gagctatgat tcgtgcacgt caagctaaaa aataacgaat atggaaaata aattaatcgt
     2821 atcactatcg ccccacgttc atggcggaga cagcgtacag aaaaatatgt atggcgtgct
     2881 aattgcactg attccggctt ttctggtgtc tctctatttc ttcggactgg gtgccctgat
     2941 tgtcacggct acttccgttg cggcttgttt gttcttcgaa tgggcgatcg gaaaatattt
     3001 aatgaagaaa ccgaccacca ccatctgcga cggctctgcc atcatcacag gtgtgttgct
     3061 ggcatttaat ttaccgtcta acttgcctat ctggattatc atcctcggtg cactgtttgc
     3121 tatcggtgta ggtaagatgt ctttcggcgg attaggctgc aatcctttca acccggcatt
     3181 ggcaggccgc gtattcctgc tgctttcttt cccggtgcag atgaccagct ggccggtagt
     3241 cggacagttg accgcttata cggatgctac caccggtgcc actccgctgg ccttgatgaa
     3301 gcaagccatt tacggtgaca ctgccgcttt aagccagatt ccggacgcat tgaccttgct
     3361 gatcggacag aatggcggat gcttgggtga agtgagtgcg ctggctctgc tgatcggact
     3421 cgtttatatg ctctggaaga aaatcatcac ctggcatatt cctgtgtcta tcctggctac
     3481 tgtgtttgtc tttgcaggca tcatgcacct ggcagatccg gaaaaatacg tttctccggt
     3541 attgcagttg ctttccggtg gtctgatgct gggtgctgtc tttatggcaa ccgactatgt
     3601 gacttctccg atgagtaaga aagggatgct gatctatggt gtatgtatcg gtctgctgac
     3661 ggtagttatc cgtctgttcg gcgcctatcc cgaaggtatg tcgttcgcca tcctgattat
     3721 gaatgcgttc actccgctga ttaacaccta ttgtaaacca aaacgctttg gggaggtagc
     3781 gaagaagaaa tgaaaaagtt agaatcatct ttaaagaata tgttgctggt acttacggga
     3841 gtgactgcta tttccgttgc gttgctggct tatgtaaatg aactgacaaa aggccccatt
     3901 gccgaagcga acgcgaagac actgaacgag gccttgaaaa aggttcttcc cgaatttacc
     3961 aataatccgg tagcggaaag cgatacgatc ttcagtgaga aagatggaaa gaagaatgtt
     4021 gactttatcg tttatccggc taagaacggt gaagagcttg taggtacggc tgttgaagct
     4081 aaatcaatgg gatttggcgg tgaactgaaa gtgctggtag gctttaatgc cgaaggaaaa
     4141 atctataact actctctgtt ggctcacacg gaaactccgg gattgggctc taaagccgac
     4201 aaatggttcg gagcgtatga tcctgcgaaa ggagaaaagg cagtatctca cgaagagagt
     4261 acgaaatcta ttttgggtat gaatccgggt gaagctccgt tgaccgtcag taaagatggg
     4321 ggagcagtgg atgccatcac agcttctacc attacttcac gcgctttctt gaatgccgtg
     4381 aatgctgctt atcaggccta taaggccgaa ggcggggaag tgaatggtgt aaccggtgct
     4441 tctcaaaaag cgaaaggcgc ggacgcagat gctgctgacg ctgctacggg agctacgatc
     4501 aaagttgaac taactgattc agtcagtgct aaataagaaa ggagacagat atgaataact
     4561 ttaaagtaat gatgaacggg attatcaaag agaatcctac gtttgtactc ctgctcggta
     4621 tgtgtcctac attgggtact acatcatcgg ctatcaatgg tatgggtatg ggactggcta
     4681 ccatgttcgt attgatctgc tcgaatgtgg tgatttcttt aataaagaac ctgattccgg
     4741 acatggtgcg tatcccatcg tttattgtgg tgatcgcatc cttcgtgacc ttgcttcaaa
     4801 tggtgatgca ggcttacgtg ccgggactgt atgctacact cggtcttttc attccgttga
     4861 ttgtagtgaa ctgtattgta ctgggacgtg ccgaagcctt cgctgccaag aataacgcag
     4921 ttgcttctat gttcgacggt atcggtatgg ggcttggctt taccatcgcc ctgactttac
     4981 tgggtgctgt ccgcgagttt ttgggaaccg gtaaaatctt cgatttgacc atcatgccgg
     5041 aagaatatgg aatgttggtg tttgtattgg ctccgggcgc tttcatcgct ttgggatacc
     5101 tcattgcgtt gattaacagt ttcaagaaag cctaattcaa ttaaataaga aaagaatatg
     5161 gaatatatat tgatatttat ttcggcaatc tttgtaaaca acatcgtgtt gtcgcagttc
     5221 ctgggtatct gtccgttcct gggcgtatcc aagaaggtgg aaactgcgat gggtatgagc
     5281 gctgcggttg ctttcgtgtt gaccatcgct accatcgtca ctttcctgat tcagaagttt
     5341 gtactggatg ttttcggact gggatacctg cagacgatta catttatcct ggtgattgcc
     5401 ggattggtgc agatggtgga aatcatcctg aaaaaggtgt ctccggctct gtatcaggcg
     5461 ttgggtgtgt tcttgccgct gattacaacg aactgttgta ttcttggtgt cgctatcctg
     5521 gtgattcaga aagactatga cctgctgaca ggtgttgtgt acgcgttttc tacagctatc
     5581 ggcttcggtc tggcactggt gctttttgcc ggattgcgcg aacagatgag tctcgtgaaa
     5641 gttccgaaag gaatgcaagg aactccgatt gctttgatta ccgccggttt gcttgctatg
     5701 gcattcatgg gattctccgg cgtggtgtaa ggatttacag ttgataatta aataggggat
     5761 tggaagctct gctgtgtggc gacatacagg ttagagtttc caattctttt tatacctaaa
     5821 tgctaccaaa tcgtacctta attacttttc agcaaataaa tttatggcag attattgcaa
     5881 ttccatttta tttccataca tttgtaactc aaacaataat aagccgagaa actaaccatt
     5941 ttttataaag tatatgaaag aaagaatttt agtaacaggc gggacaggat acattgggtc
     6001 tcatactgtt gtagaactac aaaacagtgg atatgaagta atcatcatcg ataatttatc
     6061 aaattcaagt gccgacgttg ttgacaatat agagaaagtt tccggtattc gcccagtttt
     6121 tgaaaagctg gactgtttgg actttgccgg tctggatgca gtatttgcaa aatataaagg
     6181 aattaaggca atcattcact ttgcagctag caaagcagta ggagagtcgg tacaaaaacc
     6241 gttgctttac taccgtaata acctggtttc tttgattaac cttctcgaac tgatgccaaa
     6301 acatggagta gaaggtattg tgttctcttc ttcttgtaca gtatacggtc agccggacga
     6361 gctgccggta acggaaaaag ctccgatcaa gaaagcggaa tcaccttatg gaaataccaa
     6421 acagatcaat gaagagatta ttcgtgatac ggtagcttca ggtgctccga tcaatgcgat
     6481 catgttgcgc tatttcaacc cgattggcgc gcatcctact gcattgcttg gtgaactgcc
     6541 taacggggtt cctcaaaacc tgattccata tctgacccag acagccatcg gtatccgtga
     6601 gaaacttagc gtgtttggtg acgattatga tacaccggac ggttcttgta tccgtgactt
     6661 tatcaatgtc gttgacttgg ctaaagcaca cgtgattgct atccgtcgta tcttggaaaa
     6721 gacacaaaaa gaaaaagtag aagtatttaa tattggtaca ggacgtggtg tttctgtatt
     6781 ggaattaata aatggctttg aaaaagccac tggcgtaaaa ttgaattatc agattgtcgg
     6841 acgtcgtgca ggcgacattg aaaaagtttg ggctaacccg gattttgcta ataaagagct
     6901 gggttggaaa gccgtagaaa ctttagaaga tactttacgc tctgcatgga actggcagct
     6961 gaaactccgt gaaagaggga ttcaataaaa gagaaacttg ttttaaataa cataaaagtt
     7021 taaacaaatc gtgcatgcga tttgtttaat tgatgctaat cgacctgaag ctgtttatga
     7081 gtatgcgaat atacgtagat agtacttatg cctccccggc atagacagga aagattgcat
     7141 agtagttttg tcgtgtttta ttttgtgttt gtgttgtgac ggtactacga cgtgagtcgt
     7201 ggtaccgttt tttggtacgc ccagcatgga tgttctgttt tataaaatat ttagcactaa
     7261 ttcttttgtt atccaaaatt attttgtaat tttgtatcaa atgaataaga tatgagagta
     7321 gtatcacata agaaattgaa agatttctac gagacgaaag ggtgtgaaga ttcacgtgtt
     7381 gctttagaac gttggtatga tatagcggaa aaagcagaat ggcggaattt gtctgatata
     7441 aaagcggatt ttctatcgac tgattatgtg ggcaatcaac actatgtttt taatatcaga
     7501 gggaacaact atcggctggt agtggttgtt aaatttacgg tgggatacat ttttgtccgt
     7561 tgggtgggaa ctcataaaga gtatgataaa atagattgtt caactatata atataataga
     7621 tatgactaaa ataacgaaag aacaatacga atttgcattg gcaagagtcg aagaacttct
     7681 gcctttggtg gacgacagca ctcctgcaaa tgacaagagc atggtggagc tttctgttat
     7741 gtctgatata gtgattgcgt atgagaagga acattttcct atagaaaaac caaccgtagc
     7801 agaattgata gaattgtccc ttgaagaaaa ggggatgaca caaaaacagc ttgccagtga
     7861 aataggggtt agcccttcac gcgtgaatga ttatatttcg ggtcgctcgg aacctacttt
     7921 aaaaatagct cgcttgcttt gccgggtact caatatacac cccgctgcca tgttgggatt
     7981 ttgaaaaaat agtcaaaaca taattgttag tgagatttat ttgtttaatg tacctttgaa
     8041 gcagaataca tcagttcccc aatcaatttc cggtaagacg aatccgggag caaacagccc
     8101 gaatacggat gagccggagc cgctcatgga tgcgtagatt gctccttgat gatagagttc
     8161 ttctttgatt tctccaatga cgggatgttg cgggaataca cttgcttcga aatcattgat
     8221 taacgtatcc ttccattctt gtacaggacg ctggattgcc tccctaaccg gatatttcgg
     8281 acgatgggga tgaatgtttg aaaaggcttc ccgggtggaa acaaaaacat tcggttttat
     8341 aatcatgatt tggtagccgt ttaatgaaag ttcgaccggg gagaagatgt ttccaattcc
     8401 ctcggcaaat atcggtctgt ttttgataaa gaaagcgcag tctgctccca aagtggcagc
     8461 gtatacttcc aattgttctt cggatactcc cagctgataa tgatcgttga gcaactttag
     8521 tatgaaagcg gcatccgatg atcctcctcc cagtccggct cctgaaggga tgtgcttgta
     8581 taagtggatt tcgataggag ggagatgaaa ttccttatcc atcaataaat aggcttttac
     8641 taccagattg tcttcagggt taccggctat ttccattcca tgttggtgga gagtgaattt
     8701 tcggtcagcg ttaggggagg tacggatttc cagtgcgtct tccagagcca ccggatagaa
     8761 aactgtttcc agattgtggt atccgtccgg gcgtttttcc gtgatggaaa gtcccaggtt
     8821 tattttgata ttgggaaaag caatcatatt tctatttact attttactat ttactattta
     8881 cagtgcttca cattacaatt aatcatagct ggataatgtg aatcgggagc aaagttacta
     8941 aaatcttcat ttttccttat tcattcttcg tgattatatt ctatctttgt cgtctcgact
     9001 ggaagaattc cgtgataaat gtgataatag agtctgtcca gtcgtaaaat aataaatagt
     9061 aaatcgtaaa atagtaaata tctcgatggc cgaacagaaa agaaataccc gcaattcaaa
     9121 gtctactaaa atacaaccgg taaatgatta tggtcgtatt cagccgcagg cgcctgaact
     9181 ggaagaagca gttttgggag ctttaatgat tgaaaaggac gcttattcat tggtgagtga
     9241 aattcttcgt cccgaatcat tttacgaacg ccggcatcag ttgatttatt ctgctatcgt
     9301 cgatcttgcg gtgaaccaga aaccggtgga tattctgact gtaaaggaac aacttagtaa
     9361 acgcggagac ttggaagagg tgggaggtcc cttctatatt actcaattga gtagtaaggt
     9421 ggcttcatcc gcacatattg aataccatgc ccgtattatt gcacagaaat cgctggcgcg
     9481 tgagctgata acgtttacga gtaatattca gagtaaagcg tttgatgaaa cgttggatgt
     9541 ggacgacttg atgcaggaag cggaaggtaa gcttttcgag atctcacagc agaatatgaa
     9601 aaaagattat acgcagatca atccggtgat tgacgaagcc tataaactaa ttcagaaagc
     9661 tgcggctcga accgatggtt tgagtggtct ggagagtggt ttcacgaaac ttgataagat
     9721 gacttcgggt tggcagaatt ccgaccttat tattatagct gcccgtcctg ctatgggtaa
     9781 gactgctttc gttctttcaa tggctaagaa tattgcggtg gattaccgga acccggtggc
     9841 gttgttctct cttgaaatga gtaacgttca gttggtgaac cgtttgattg cgaatgtctg
     9901 cgagattccg agcgagaaaa tcaaaagcgg gcagttggca aattatgaat ggcaacaact
     9961 ggactataaa ctgaagaatc tgatggatgc accgctttac gtggatgata cgccgtctct
    10021 gtctgtgttt gaacttcgaa ccaaagcgcg tcgtttggta cgcgaacatg gggtgcgaat
    10081 catcatcatt gactaccttc agttgatgaa tgcgagtggg atggcgtttg gtagccgtca
    10141 ggaagaggtt agtaccattt cccgttcgtt gaaaggattg gcgaaagagt tgagtattcc
    10201 gattatcgca ctgtcacagt tgaatcgtgg tgtggaaagt cgtgaaggta ttgacggtaa
    10261 acgaccgcag ttgagtgacc ttcgtgaatc gggagccatc gagcaggatg ccgatatggt
    10321 gtgctttatc caccgtccgg aatactataa gatatttcag gatgatcgtg gtaatgactt
    10381 gcgcggtatg gcggaaattg taatcgccaa gcatcgtaac ggtgcggtag gcgaggtgtt
    10441 gctccgcttt aagggtgagt ttacccgttt ctctaatccg gaggacgata tggtgatccc
    10501 gatgccgggc gagcctgcag gagctatgtt aggatcgaaa atgaatacag gtaatgctgg
    10561 ttccatacct cctcccgcac ctgattttgc accgcagacg gagaatccat tcggagcacc
    10621 gggagatgga ccgttaccat tttagttaat agttgataac tgatagtgaa aatgctctgc
    10681 gcaacatttc ttctatctgt atgttattcc gcatggtaac tatcaactat aaactttttt
    10741 atctaacctt ctcggtcaac cgaaaaatct tattaacttt gcaaatcttt ttgagaaaca
    10801 ataaaaaatt aaatatatga atatctctta taactggctg aaagagtatg tcaacttcga
    10861 cctgacgccc gatgaaacgg ctgctgcgtt gacttctatc ggcttggaaa caggtggtgt
    10921 agaagaagtg caaaccatta aaggtggttt ggaaggactg gtgatcggtg aagtgctgac
    10981 ctgcacggaa catcctaatt ctgaccattt gcatattact actgtcaatc tgggagacgg
    11041 tgaaccggta cagattgttt gtggtgcccc gaatgtggct gccggacaga aagtggtggt
    11101 agctacttta ggtacaaaac tttatgacgg tgacgaatgt tttaccatca agaaatcaaa
    11161 aatccgtggg gtggaatcta ctggtatgat ttgtgccgaa gacgaaatcg gtatcggtac
    11221 ggatcatgca ggtattatcg tattgccgga aaatgctgtt ccgggtacgc ttgccaagga
    11281 ttattataat atcaagagcg actatgtgct tgaagtggac attacgccta accgtgcgga
    11341 cgcttgctct cactatgggg tggctcgtga cttgtacgct tatctgattc agaacggcaa
    11401 acaggctact ttgcaacgtc cgtcggtaga cggttttaaa gtggaaaacc atgacttgaa
    11461 tattgaagtg aaggtggaaa acagcgaagc ttgtccgcat tatgccggtg ttacggtgaa
    11521 aggtgtcact gtgaaggaaa gcccggaatg gctgcaaaac aaattgcgtc tgatcggggt
    11581 gcgtcctatt aataatgtag tggatattac taattatatc gttcatgctt tcggtcagcc
    11641 gttgcattgc ttcgatgccg gaaagataaa aggcaatgaa gtaattgtaa agacaatgcc
    11701 ggaaggaacc ccgttcgtta cgctggatga ggtggaacgt aaattgaacg aacgcgacct
    11761 gatgatttgt aacaaggaag aggccatgtg tattgccggt gtattcggcg gactggactc
    11821 cggttctacg gaagctacga cagatgtatt cattgaaagt gcttatttcc atcctacatg
    11881 ggtgcgtaag acagcccgcc gtcatggctt gaatacggat gcttctttcc gtttcgaacg
    11941 cggtatcgat ccgaacagtg tgatatattg cttgaaactg gctgctttga tggttaaaga
    12001 actggctggc ggtacgattt cttctgaaat aaaagacgtg ttcactactc ctgcacccga
    12061 ttttatagtt gatctggctt atgagaaagt acattctttg gtaggaaaag taattccggt
    12121 agagacaatc aagagcattg tgaccagcct ggaaatgaag atcactaatg aaacggcgga
    12181 agggctgaca ttagctgttc ctccttatcg tgtagacgtg cagcgtgatt gtgacgtgat
    12241 tgaagatatt cttcgtatct acggatataa taatgttgaa atcccgacta cactgaactc
    12301 cagcctgact accaaaggtg aacatgataa atcgaataaa ttgcagaacc tgattgcaga
    12361 gcaattggtg ggctgcggat ttaatgagat cctgaacaac tcattgacgc gtgctgctta
    12421 ctatgatggc atggagactt atccgtccaa ccacctggtg atgttattga atccgttgag
    12481 tgcggatttg aacgctatgc gtcagacttt gctgttcggt ggactggaaa gtattgctca
    12541 taatgcaaat cgtaagaatg ctgatttgaa gttcttcgaa ttcggtaatt gctatcattt
    12601 cgatgctgac aagaagaatg aagagaaggt attggctcct tactcggaag attatcactt
    12661 gggcttgtgg gtaaccggta agaaggtttc caattcatgg gcacatgcag atgagaacag
    12721 ttcggtatat gaattgaagg cttatgtaga aaatatattg aagcgtctgg gactggattt
    12781 gcacaatctg gttgtcggta atctgacgga cgatattttt gctgccgcac tttctatcaa
    12841 tacgaagggt ggtaagcgtc ttgcttcctt cggtatcgtg actaagaagc tgttgaaagc
    12901 atttgatatc gacaatgaag tgtattttgc cgacttgaac tggaaggaac tgatgaaagc
    12961 tatccgttct gtgaagatca gctacaagga aatctccaag ttccctgctg tgaaacgtga
    13021 cctggcattg ttgcttgaca agaatgtgca gtttgccgaa atcgaaaaga ttgcttacga
    13081 aacagagaag aagctgttga aagaagtgga actcttcgac gtgtacgaag gtaagaatct
    13141 ggaagcaggc aagaagtcgt atgcggtgag cttcctgctt caggatgaga gccagacttt
    13201 gaatgataag atgattgata agatcatgtc gaaactggtg aagaacttgg aagataagct
    13261 gggtgccaaa cttagataaa cttaaaattt caatctaaaa atataaacca atgggaagag
    13321 catttgaata tagaaaggcc gctaaactga aaagatgggg ccacatggct aaaacattta
    13381 caagactggg taaacaaatc gcgatagctg taaaggcagg cggtccggaa cctgaaaata
    13441 acccgacttt gcgttcggtg atcgctactt gtaagcgtga aaatatgccg aaggataata
    13501 ttgaacgtgc tatcaaaaac gcaatgggta aagaccagag cgactacaag agcatgactt
    13561 acgaaggata cggtcctcac ggtattgctg tatttgtgga tacgctgaca gataacacaa
    13621 cccgtacggt ggctgacgtt cgttcggtat ttaataagtt tggcggtaat ctcggtacaa
    13681 tgggatctct cgcgttcctg ttcgaccaca aatgtgtatt cactttcaag aagaaagacg
    13741 gattggatat ggaagaactg attctggatc tgatcgatta tgatgtggag gatgaatacg
    13801 aagaggatga tgaagaagga acaatcacta tctatggtaa tcccaagagc tatgccgcta
    13861 ttcagaaaca cctggaggag tgtggctttg aagatgtcgg tggagacttc acttatatcc
    13921 cgaacgacat gaaagaggtg actccggaac agcgcgaaac attggataag atgatcgaac
    13981 gtttagaaga atttgacgac gtgcagactg tttataccaa tatgcagccg gaagagggag
    14041 aataagacaa ggttatggaa tatgtgtata gaacccaggg aacttgtagc accaacatcg
    14101 aactgaatgt ggaagatgga gtggtgaaag aagttgcttt ttggggagga tgtaatggta
    14161 accttcaagg tatttcccgc cttgtgagag gaatgaaggt agcggatgtt atcgcaaaac
    14221 ttgaaggagt gcattgtggt ggcagaccga cttcatgtcc tgaccaattg tgtcgtgcat
    14281 tacatgagat gggatattaa tcgacttctt ttatttttgt aaaatttgat atttttcaag
    14341 accttcggca atttattttg tcgagggtct tttttttgtg ggaatccata ggggggggat
    14401 ccgggtgttg tttacttact tgtcggtatt ttgaactaaa attgaccttc actcgttatt
    14461 tataagtata tttgtaaggt taaaactatt atgcaaaaat gaagaatatt tttcaagact
    14521 taaaacgcaa agatcataaa cgctatctgg gtggactgga tgtttttaaa tatattggtc
    14581 cggggcttct agttacggta ggatttattg atccgggaaa ctgggcttct aacttcgccg
    14641 ccggttccga atttggctat tccttacttt gggtggttac attgtccact attatgctga
    14701 ttgtgcttca gcacaacgtt gcccacctgg ggattgttac cggactttgc ctttcggagg
    14761 cggccactaa atacactccc aaatgggtgt cgcgacctat tcttggtacg gcggtactgg
    14821 cgtcgatttc tacttcttta gcggaaattc tgggaggtgc cattgcgttg gaaatgctct
    14881 ttgatattcc tattatatgg ggagctgtgt tgactacgct ttttgtctct atcatgcttt
    14941 tcactaattc gtataaaaag atagagcgtt ccatcattgc atttgtctct gttatcgggc
    15001 tttcgtttat ctatgaactg tttctggtgg aaatagactg gccggctgcg acagcagggt
    15061 gggtgactcc ttcttttccg aaaggaagta tgctgattat catgagtgtg ttgggagcgg
    15121 tagtgatgcc tcataatctg tttcttcatt cggaggtgat acagagtcac gaatataata
    15181 agaaagatga tgcttctatt aagaaggtct tgaaatatga gttgtttgat actcttttct
    15241 caatgattgt cggctgggcg attaacagtg ccatgattct tctggctgcc gctactttct
    15301 ttaaaagcgg tattcaggta gaggaactgc aacaggctaa gtcattgctc gaacctttgt
    15361 tgggaagtaa tgctgccatc gtatttgcac tggcattgct gatggcgggt atttcatcca
    15421 ccattacgag cggaatggcg gcaggttcca tctttgcggg tattttcggt gaatcgtatc
    15481 atatcaaaga cagccactcg caggtaggag tccttttatc tctgggaatt gccttattgc
    15541 tgattttctt tattggagat cctttcaaag gattgattat ttcgcagatg atacttagta
    15601 ttcaattacc tttcacggta tttttgcagg tgggactgac gtcttcccga aaggtgatgg
    15661 gagattatgt caatagtcgt tggagcacgt ttgtgttgta ttcgattgcc attattgttt
    15721 cggtactgaa
//
