LOCUS       c00004_gnlPro..        13205 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFGAHNFM_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:17:16
            Original ID  :: gnl|Prokka|NFGAHNFM_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13205
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13205
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[246:3205]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      247..3205
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13205
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13205
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             247..2475
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Gly_radical (E-value: 2e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2480..3205
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3438..4697)
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(4752..5300)
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5488..6240
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6345..7343)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="LysR_substrate (E-value: 2.9e-46,
                     bitscore: 149.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.2e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMELKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7413..7886
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(7990..8988)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 2.3e-69,
                     bitscore: 225.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDINQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9043..10311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_9"
                     /sec_met_domain="MFS_1 (E-value: 1.5e-11, bitscore: 35.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRCAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10561..11574)
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDATAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPGGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11597..12733)
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 ggttaagtag tgcttttctc ttaaagcgct gcaaaggtac gaatcatttt ttaacttgca
       61 aattattccg caaaaaaata ttagaaaagt atatttggaa gtaataaccg ccctctggct
      121 tctccccata aataggtatt tttatgctat tcaacataaa ataggaccct tttatatacc
      181 taaaccgaaa aaaggttgta aatttgcgcg ctctaaagga taactaacca ctaactgatt
      241 aattttatgg aactgaataa gacctttaaa gatggacttt ggagcaaaga aatcaatgta
      301 agggatttcg ttagtaacaa catcactcct tatgaagggg atgcttcttt cctgcaagga
      361 cctaccgaac gcaccaaagc tgtctggaat cactgtctca aagctctcga agaagagaga
      421 aacaataatg gtattcgtgc actcgactac acaactgtat ctactataac ctctcaccct
      481 gccggctaca tcgataaaga aaacgaactg atcgtcggac tacagaccga tcaggtgtta
      541 aaacgtgcca tcaaaccgtt tggcggaatc aatgtggtta tgaaagcttg ccgtgaaaac
      601 ggagtggaag tagatgacag agttaaggat atcttcactc actatcgcaa gactcataat
      661 gatggggtat tcgatgtgta taccgaagaa attcgttcgt tccgttcatt gggattcctt
      721 accggacttc ccgacaacta tgcacgcgga cgtatcatcg gtgattatcg ccgcctggct
      781 ctctatggtc ttgaccgtct gatagaagct aaaaaagaag atctgcataa tctgacaggt
      841 cctatgactg aagcccgcat tcgtcttcgt gaagaagtag ccgagcaaat caaggccctg
      901 aaagagatta aagtattggg cgaatattat ggtttggatc tgagccgacc ggcatatacc
      961 gcacaggaag ctgtacaatg ggtgtatatg gcttatctgg ctgccgtaaa agagcaggat
     1021 ggtgctgcca tgtcactggg taatgtatct tcattcctcg acatctatct tgaatatgaa
     1081 ttaagccagg gtacgataac cgaaacattc gctcaggaac tgatcgacca attcgttatc
     1141 aaactccgta tggtacgcca cttgcgtatg cagtcgtaca acgatatttt tgcgggtgat
     1201 cccacatggg tgaccgaatc tatcggtgga cgtttcaatg acggacgtac caaagttact
     1261 aaaacttctt tccgcttctt gcagacactt tataacttag gcccgtcacc ggaacctaac
     1321 atgactgtac tatggagccc tgagttaccc gaaggtttca aagcattctg tgcacaagta
     1381 tctatcgaca cttcttccgt acaatacgaa aacgacgacc taatgcgtga agtccgtcaa
     1441 tcggatgact acggaatcgc ttgttgtgtt tcatatcagg aaatcggaaa gcagattcaa
     1501 ttcttcggcg cacgtgccaa ccttgccaaa gccctgctac tggctatcaa cggaggacgt
     1561 tgcgaaaata caggtacagt tatggtaaaa gacatccctg tattgaccgg tgaaacactg
     1621 aagttcgaag aagtaatggc caactataag aaagtattga tacaaattgc acgtgtatac
     1681 aacgaagcaa tgaatatcat acattacatg cacgataagt attactacga aaaggcgcag
     1741 atggctttcg tggatactga tccccgcatt aacctcgctt atggtgtagc cggactttca
     1801 atcgccatcg attcactgtc cgccatcaaa tatgcacatg tgaaagcccg tcgcaacgac
     1861 atcggactga cggagggatt cgatatcgaa ggtgctttcc cttgtttcgg taatgacgat
     1921 gaccgtgtag accacttggg tgtggacctg gtatatttct ttagcgaaga attaaagaaa
     1981 ctccccgtat ataagaatgc ccgtcctacc ctttcgctgc tgactatcac ttcgaacgta
     2041 atgtatggca agaagaccgg tgccactcct gacggacgcg ccaaaggcat tgcctttgct
     2101 cccggtgcca accccatgca cggacgtgat aaaaatggtg caatcgcctc actgagttct
     2161 gtagccaagt tgcgttatcg cgactcacag gatggtatca gcaatacatt ctcaatcgtt
     2221 cccaaatcat tgggagcaac acaagaagac cgtatcgaca atctggtgac catgatggac
     2281 ggatatttta caaaaggcgc acaccacctg aacgtaaacg tgctgaaccg ggaaatgttg
     2341 caggatgcga tggaacatcc cgaaaagtat ccgcaactga ctatccgtgt ctcaggatat
     2401 gccgttaatt tcgtgaaatt gagccgcgaa catcagttgg aagtaatcag ccgcagtttc
     2461 cacgaaagaa tgtaattgaa tgataaacgt acactcatac gagtcaatgg gaacattcga
     2521 cgggccgggt ctccggctcg tcgttttcct tcaagggtgt aacttccgtt gcctctattg
     2581 tgccaatccg gacacaattg aagccaaagg agggacagca accgaccctg aggaaatagt
     2641 tcgcatggcc gtcagtcaga aagctttctt cggtaaaaag ggaggtatca ccttttccgg
     2701 cggagagcct acttttcaag caaaatcgct tatcccactt tttaaaagac taaaggaagc
     2761 aggaatccat atttgccttg ataccaatgg cgggctatgg aacaatgatg tagaggaact
     2821 attggaattg actgatctgg ttttattaga tatcaaagaa tttaatccgg aacatcatca
     2881 gtctttaacc ggaagaagca acgagcagac cctgaaaacc gcagcctggc ttgaaaccaa
     2941 tcataaacca ttctggttgc gatacgtatt agtgcccggc tacagtgact tcgaagacga
     3001 tatccggcag ctgggagagc atcttggaac gtaccagatg attcagcgtg tagaaatatt
     3061 gccttaccac accttgggtg ttcacaaata tgaagcaatg aacaaagaat atatgctgaa
     3121 aggagtgaaa gagaatactc cagagcagat agaaaaggct gagaaactat tcaggcaata
     3181 tttccagacc gtacaagtaa attgacttat ataagtgtcg aaactcgtat tcgccacaga
     3241 ttacacgaat ttacacagat aaagattcat tggccatcaa tagattaagt tcactctgcg
     3301 gtgaattatg acgactgcac ttatttataa ttttgtaagt cacgatataa aagtctccct
     3361 gttcttgcct taattcatta caatacaagg caagaacagg gagataatgt aaccggcata
     3421 ttttttgcca ccctacttta ataagtgaat cgcaatcctg cctgcaagtt aaagttacaa
     3481 ggcctttctt ttcggatggt ttgtactttg gagccatcat caaagaaata cgaaactccc
     3541 ggttccacat ataggccgac atgatctgtc gcattgaact gcgctcccac ggcaccggct
     3601 acagaaaatt gcaaaggctt cacattcacc ttatcatccg ccaactttcc ataaacacac
     3661 ttttcaacca ttcctccggc agatacatag agtgtaaaat atttcttttc cagaaaattc
     3721 cagtttccac gtacaggaat acctatataa tgcaatttct gactctgcat cttggtatcc
     3781 ccctgccgtt tgatatcaga agacaacaac gtataagtca atcccgtctc tacagagaaa
     3841 cctttgggaa gagacttacg tacagacagt ccgaagctaa ccggctgatg atgttcataa
     3901 tccaccacgg cagttgtatt ggacttcagg taaggaaccc cttcctcaaa tataacttcc
     3961 tgatcggcag gaatactcac agctccattc atgatcgtca tcaagtcgac cctgttagtc
     4021 atcggacggg gcgcaaaatt ttcggaacca tttgtcggaa gtccacctcc attaccgata
     4081 cccactccca tcgaccattt accaccacgt ttagcagaag agtctccgat aggcaactga
     4141 tacttgtctt taccggacgg tcgccgcgct tctttcctct ttggaggctg cgccgtcgca
     4201 ctttcttttt tctcgattgc agcaattgct tcctgttgcg gctcagatct cttttcctcc
     4261 gtcactgcct ccggtcgctt ctctaccagg gaggatacct ccggaacaat caccggatca
     4321 gtattctttg ccaaatagcc cgaaacaggg ttaatactcg tcgttcctac cggcttaact
     4381 ggttcggata cagctacctg tacatccggc aaggcaggtt ccggcaatac atccgggttg
     4441 acagccagtg aaggagccgt tgcataacgg atttcatcag ctaccgggct attcagaaaa
     4501 tacaaactga cagcagtcgt tagcaccaat accacagctg ccgcagcaac cgcccaccgg
     4561 cgatacggat atattcgttt ttcggttaca ggcatcagtt ccctttccag tcgttcccaa
     4621 ccggaagcag gcatcggctc cgaataatct tcgagcttat ccttgaatgc tttaatccat
     4681 ttttcgtctt ctttcatcat tctatttcat ttttgaaatc caaggttcac ctcagtatct
     4741 gtaaatacat gtcaaccatt ggtcaccaac cattctttca ctttctttgc caatacactt
     4801 tttgcgcgaa aaagctgtga ggcagaagat ttttcattaa tccccaacat ctgtgcgatt
     4861 tccttgtgcg acttatcttc aaaggtgtat aaattgaata cggtacgata tccggcgggg
     4921 agttcattaa taaattgcat cagcactttc tgtggtattg cttcaacagc cgaagcatcc
     4981 ggttcttcat acgtttcggg aacttcatcc agtgccgtgg tctggttcat cacgtcgttc
     5041 tttcttaaga actgtaaagc cgtattcacc attacacgct ccatccatgc tctcagagag
     5101 ccttcacccc gccaggtaaa cttgtcgaag gagtcgaaaa tcttcaggaa accgtcgtgt
     5161 accaagtctt gtgccatatc cctgtctccg gcataacgaa gacagacacc aagcatgcgc
     5221 cctgcgtact gctcataaag ttctttgcgg gcacgattat ctccctgcct gcaacgttcc
     5281 gacagctcta attcattcat tctcctaaac acgtgtttac cttataaatg cagcaaagat
     5341 agaaatactg cacagagaga acaactcttt tatcactttt gtttctttaa cattttagga
     5401 tgcaatatat catcacttcc tgcattttct caatacaata aagaataaat ctcaatggat
     5461 aaataggata aaaccaacaa gaaacttatg aagaaattta atttaataac ttttgccgtc
     5521 atcctgatgt tattgcccat tttacagtca tgtctggacg atgccaacaa cgacgagtgg
     5581 gtcacttgtc ctccgggtgg aatattggcc atcggcacaa tgaagattcc caatgcggac
     5641 actccaaggg actttttcat tgcgttggac aatggagaca atgtacttcc ggcagatacg
     5701 gccgatatac gcaacaggaa atacactgtt gcagaaggac aaagagtctt cgttggctat
     5761 ctgcagatgg gagaagagaa acctggatat gagaacggta aaatattcac gatagaagat
     5821 atattgacga aagagatcat cccactgacg gaagctacag cagacagcat tggagacgac
     5881 cgtatcaacg tcacagcgca tgcacttacg aaagattatc tgaccatcga atatcaatat
     5941 ctgggcagca tgaatgaaaa taaaaaacac atgctgaact tggtacaaaa cgaaataaca
     6001 ggtcccataa aagatgacgg atatatctat ctggagttcc ggcataatgc ctttaatgac
     6061 tcccccaatc aattgggttc gagccttgtt tctttcaagc tggatagtat agccgagcaa
     6121 ttggcgacag ccaaaggaat aaaactccgt gtgaacacca tttatgacaa tatacagtat
     6181 gtcacaatag atatcaacga agacaaaaac ttaaaaataa aatcatttca ttctcaataa
     6241 aacaacaaga aacacctaca caatcaggca aaacgagtaa taattctgat acataaaaga
     6301 aataaggcgg cgatgtttgt gaaaatatcg ccgtcgtttt tatattatac cagacactga
     6361 acggcctgca gggtaagcat ctccttggga accgccgcct gaatctcctc tttcaaaacc
     6421 tgcagcagac tggtgcggat gaagtctttc cgggtcacca ggacaatctg acgggtaggc
     6481 cgcgggatag caaacggacg gaccagttct ttctgctctt cgctcaattg catcactgcc
     6541 agttcgggaa taaacgtaat ccccttacca ctctccacca tatgcataaa ggtttccata
     6601 ctacccagcc gatacgccat ttggctgatc ttaaccgctt ccatctgaca aaaacgaacc
     6661 aactgatcgc ggaagcaatg cccttcgtca agaagccaaa gccgttcccc tgtcacatcg
     6721 gacgtacgaa tcacatcgtg cttgaacaac ggttccttct ttgagacata gcccaggaat
     6781 tgctcgtaaa ataaggtctc ttccgttaat gcggcatcat ccagcatgct ggcaatgata
     6841 gcagcatccg cttcaccggt cagcagagcc ttgcgaatgt cgggcgtctt cagctccatc
     6901 acccgtatat caagatccgg gtatttctcc atcagttgcg gaaagaaacg gggcagaaga
     6961 taaggtgcaa tcgtcggtaa cactgccaat cggaatgtac ccgacaggga gtgctgttct
     7021 tcgctgatga tctccttgac acagataact tccgaaagaa tcttacgggc ctgttccagc
     7081 actttcttac caatggcagt agggcaaacc ggtgtcatgc tacggtcgaa cagtttcacc
     7141 cccaattcgt cttccagctt ttggatcatt gcactcaaag taggttgcgt cacccggcaa
     7201 tactcggcag ctttagcaaa atgccggaac tggtccacag ccagaatata ttccaattgt
     7261 tgtatagtca tcgttctctg atttattaaa gatatagaat ctatcaatgc aaagatagaa
     7321 attttcagtt tgacacgaat cattttgtgc cgtatctttg ttccagataa aaagaagaaa
     7381 tatagtatta actcaaaaaa aacaatatca ttatgaagac tttaaattat acacatttgg
     7441 aagaaaaagg agctaacacc atcgtactgt cattacagca actgcttgcc gattttcaga
     7501 ttcattatgc aaacctgaga ggatttcact ggaacatcaa aggacacggt ttcttcgtac
     7561 tgcacagcaa gtttgaagat ttatataatg gagccgccga aaaggtggac gaaatagccg
     7621 aacgtatact gatgctggga ggaactcccg ccaataaata cagtgactat ctgaagatgg
     7681 cgcagatcaa ggaagtggac ggagtgaata aggccgacga cgctctgaat catattctcg
     7741 aaacttacgg gcatctgatt gcggaagaac gtaaaatcct gtctctcgcc tcttcacaca
     7801 acgacgaagt aacagtggcc atgatgagcg actacctgaa agaacaggaa aagatggttt
     7861 ggatgctgac tgcatacaac ggataacagc cgaaagggtg tagccatctg accgaaaagg
     7921 tgtagccata caaacaaaag ggtgtagcca tcccggcggg atagctacac cctttctgtt
     7981 ttattcgatt cagatgatac ttgtacgttt ggtaaattca ataatctccg gaatgtatcc
     8041 gaatgcgagc ccggtcactg tatccgcaca cccataatag atggcaatcc gtccggtctc
     8101 cgaatcatga agcgccgcgc atgggaaaca gacattaggc acatcaccca tacattcgta
     8161 atccttctga ggtgaaatca gataaggccc cgaacggaat tttactttcc agggctgatt
     8221 gatgtcaagc agtgccgaac caaaactata cacaaaaccg ttgcaggaag ccaatacacc
     8281 atgatagatc agtaaccagc cttccgaggt ttcaatcggg ataggccctg caccgatctt
     8341 ggtacactgc caggcactgt cttcgaacgg agccggcgac ataacatgac gatgacgtcc
     8401 ccagaactcc atatcgggag actcgctata gaaaatatct ccaaaaggag tatgcccatt
     8461 atcactcggg cggctcaaca tcgcaaaacg accgtttatc ttacgaggga acaagactcc
     8521 attccgattg aagggaataa aggcattctc caactggtga aaagtaacaa aatcataggt
     8581 gtaggccaca ccgatagtag gaccatgata gccattacac caggtcacat agtagcggtc
     8641 ttcgataaag caaacccgtg ggtcatatcc atagacccag gttccaacct cagcgtcatc
     8701 acattgaaac tttaacggtt cttcgttgat atcccaatga acagcatcct tactgaatcc
     8761 cacatgcaaa cgcatgcgac gattagtatc atcacaacgg aacacccctg catagccatc
     8821 cttaaacgga actacggcac tgttgaatat actgtttgaa gtagggagca agtcgcgcgg
     8881 aataatcgga ttggccgaac aacgccacac tacatcttta catcctgccg gacgttcttc
     8941 ccaaggcata gccggcaaag cagcacctgc aattttaatt tcttccatga ttcgattaaa
     9001 ttaatattat gtatatatct tgtttatatt gaaaatctct ttttatttct tctttccgtc
     9061 cggatatgtg aaaggtacca gccaagtcac gataaaagcc ggtatggtag cgataagtac
     9121 ccagataaag aaatcgcgat aacccagcca atcgctcagg tatccgctca tcattccggg
     9181 aagcatcacc cccagattca taataccggt agcaaaagca taatgtgcca tctgatgttt
     9241 gccgggagcc acttgctgca tcataaagag catcaatccg acaaaaccaa acccgtaacc
     9301 caagtattca gacacaatgg ccataccaat aatccataga tcggaaggct ggtaaagggc
     9361 taacaggaaa tataccaaga acggaatatt aaaagcgcaa cataaagaaa acaaagtctt
     9421 ccgaagtccg aaagccgaaa tgtaataacc ggccaaaagc gaaccgagaa taaaagctcc
     9481 cgctccgaac gtaccatata ccagtccgat atcctgagtg ctgagtccca atccaccatc
     9541 cgcaaccgac gctttcagga acaacggtac aatcttgatg gcatatcctt cggcaaaccg
     9601 gtacaaaatg ataaagacaa tgtagaaagc aatatgtttt ttttggaaaa aagagcggat
     9661 gacttcccaa agcatattca atgcgtcact catcgtattc acttcaccgg aagcgcctcc
     9721 tcccgaaggc aaaatccgga tgtggtaaag accgatcaga atcataatac ccgcacacat
     9781 caacatgaca atcatccagg catgtaccac tccaaattca tccttcagca tacctgccag
     9841 ccaaaccaag cctccgttgg caagtatctt ggccagatta taaaaagctc cctgccaacc
     9901 gatatacttg gcttgctggg tagcagtcag ttcagtcagg tatactccgt cacccgcaat
     9961 gtcatgagtc gcaccactga gagcaatgat ccccatcaga gcgatggcac aacgaaaaaa
    10021 gtcgggcagc ggcagcgaaa gtgctaccaa tgcaaatgcc agtccggtaa tgatttccgt
    10081 agcgacaaca aagtattttt tcgttttaaa catttccaga aacggactcc ataaaggctt
    10141 caatgtccag ggaagcataa tgagagaagt ccagaaagca atctgtgcat tcgacacttc
    10201 catatcggaa aacataagga cagaaaccat cgaaagggcc acaaacggca atcccatagc
    10261 aaagtaaaca gtaggcaccc aacatacagg gcttatcggc tttttattca tcagttagtt
    10321 ttttataata attccatcgg ttaacaattc cagtaagcaa agatagggga tattaaaaac
    10381 ataacccaag attacgacaa gaagttgctt tcattattta ataatacaac tcacccggga
    10441 aaactactaa cctctatcac ccttttttta ttaaacttta tcaatacaat acacgcaaag
    10501 aagcaccgaa gactttcatc cccgatgcct ctcgccccct tatctacaat ctaaacacct
    10561 ctattgcttc acatataaat ttatctcagc aaacccggta taattatccg gagtcagaca
    10621 gtttattctg aattccttta cattcgggat aggtggttcg atggccgcat attgcggatc
    10681 agccccttta aaatttctga aagtcaagac tctcgggtaa gtaacccact cggtttcacc
    10741 ctctttccga accttaatct cagcacttct cagattataa cccgatccgt aggcactctg
    10801 tttagtgacc gaaaatccgg ttaaggtaac aggccggtcc agtaccgtat tccaccaaca
    10861 ctctccggca ttagccactc cccatgtaaa ccaagtagta tttatctcac cgtcaatagc
    10921 cagatgtgca ccatatttgg catcatcatc ggcataaaca ttgctgcaac ttacactcca
    10981 cgcacttcga tctacagcgg accaattccc gggtttcgta taactggtat aaagcacgct
    11041 ggtataaatc cggatataaa ccgtcttcat agatgtactg acagcctgtt cgtccatgcc
    11101 cgtaactcct ttaagcgtca cgggaagcac atatccgcca ggattagtca acttttctat
    11161 attcttcaaa acgacctgaa aagatgaatc ggccactgtc tgtcccgttt ttaagacaac
    11221 ttcacttgtt tcaatggtat aattatcttg gggcaacaac ttacatttcg tcttattggc
    11281 agaattgtaa gtatccactt tcagcgtatc tactcccaaa gcggcagtgg catcccgcgt
    11341 aaccggctgt acggcacaca attgtatttc aaaatcagaa cggtcggcag tagaggaatt
    11401 gctcacacaa tccaccacta ccgcagcacc catttcggcc cccggtgcaa ctcccgttct
    11461 gatatatatc ttttgatatt tgtccatttc atcatcatcg ttgctgcacg aagccaacga
    11521 tacaaagcct gttatcaggc agattaaggt cacaaaattc aaatgtctat tcatatctta
    11581 tcttcttttt acatagttat tgcttatcaa aacgaacatg ctctttccag acaagagttc
    11641 ctcctgccac caaatcgtat ccgtgtccgg tacagtcggc aaaggcattt cctttacctt
    11701 catccatttt ccaatagcct atcaggttcg gatcggcggg tttcacggca aaatacatgt
    11761 tggactgaat ttgcgtctgg ctgattgcgc tcttccaaag acgcacctgg gccatctgac
    11821 aattgttgcg gaagtagcta ccgctcgaaa ccatgttcat cttgtcgaat cttaccgggc
    11881 caccctttgt ctgcagagtc acgtcgagca ctccgttgat ataaatcgac aataacccgg
    11941 aagaattata aacgaaggcc agatgatacc acttattctt ctcaaacaaa gtcaccgtat
    12001 tgacctgact tccaagtgtc ttcacctgta atgaattata agggatcata gcgtcaccga
    12061 aacggatata aacctcgtgg tcgctgctgc ccgaattaaa tatagcctga ttattaatat
    12121 cgaatccgtc catctgtacc caagcctcga gtgaccattc attggttgtc actccccaca
    12181 attcgtcctt ggcgggcttc acggcattgg tcgtattcat aaacggtaca gactgtatca
    12241 gcggcttatc cagcaaaatg ataaacttcg acgaaagccc gattgtagac accggtccct
    12301 gaatttctgt gagagatacc ggaatagcat acaattctcc gttttcgttt gaataaggtt
    12361 tcactctaaa ctcactgggg attgcgctaa catcgcctgc cgctatcttt atctctttgt
    12421 cataagtaaa atactgctcg ggaaggactt cgtacgaagt ttcattagct tcattgtact
    12481 ctttaagaat agaaggatct accgtcagga cagcagtcac attttcggtt acaggctgtc
    12541 ccacacgtac ggtcagagta gttgttgtta cattttcagg atcaacggta acctttgccg
    12601 aaccattctc ggatgcttca ttcaaataaa tcgcattgtc gataacctgg taatcggcat
    12661 cgttgcatcc tgccaggatc atcggcagaa cgaaacaggc aagcaaacat tgttttattg
    12721 ttattctttt cataatcaaa ttctttaaag tcattttaca gcaggattca ttattctgat
    12781 tgcttcacgc aggtacttat attcgatgtc gcccggatag tcatattcca tgtgataggt
    12841 gcctactcca cccttccgta cctgttttcc gtcaatagtc ggagtccagc gtgccatgcc
    12901 ggcaagtgct ctcattttgt ttccgtaacg atctacataa tcacctcctc ctgtcggagc
    12961 ataagattcg aaattctccg taacgatgta catattagcc actttctccg gaggaagtat
    13021 tcctttaaag ttggcaatcg taccagccag acgtctgtca agattagcgt cggaattacc
    13081 cgcaaggtta gagtatgcct gcacaatgaa atagtcaaag taaggcccgg tttccggatg
    13141 aatactttga ggctcgccat caatcacaag taaccgtccc gtacctgatt taggtccgat
    13201 tcttt
//
