LOCUS       gnlProkkaNDLLCADB_32   12576 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NDLLCADB_32.
ACCESSION   gnlProkkaNDLLCADB_32
VERSION     gnlProkkaNDLLCADB_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 19:30:57
            Original ID  :: gnl|Prokka|NDLLCADB_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 262838
            Orig. end    :: 275414
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12576
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10345]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12576
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12576
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(187..972)
                     /locus_tag="ctg32_235"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQIPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLVYDKKHGAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SEQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(996..2162)
                     /locus_tag="ctg32_236"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDEDDDLDYEYEEEDWEEK"
     CDS             complement(2175..2744)
                     /locus_tag="ctg32_237"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             complement(2778..3314)
                     /locus_tag="ctg32_238"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3356..4900)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.2; E-value: 3.6e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_239"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTN
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5094..5318)
                     /locus_tag="ctg32_240"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             5591..6424
                     /locus_tag="ctg32_241"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHIELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLNEENAIPIKGEYKLREYYRITIKEDNG
                     KVIDTFYITKNFLQFLDTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             6955..8466
                     /locus_tag="ctg32_242"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTSEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDASETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8540..9604
                     /locus_tag="ctg32_243"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNTVVPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRDK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             9626..9907
                     /locus_tag="ctg32_244"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(10001..10345)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_245"
                     /sec_met_domain="PF05402 (E-value: 8.8e-17, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 3.7e-09, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             complement(10390..11778)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_246"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(12069..12464)
                     /locus_tag="ctg32_247"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEASATETPAPAAE"
     CDS             complement(12471..12575)
                     /locus_tag="ctg32_248"
                     /transl_table=11
                     /translation="MIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
ORIGIN
        1 gtccatcgca gtaagcagta ttcttcactg ctgcatatac ggctgctccg gcaaaaaccg
       61 gacaggcatt ctttatttcc tgagatactt ttatttcaaa catactttta ttcaagttta
      121 tatcaactta cgttcaagtc tattccaacc tatgcgctta tttatgtcaa tctatgttca
      181 aagctattat ttatgaatca tgatccccga cagaatccgt ccggacttaa tgcccaaacg
      241 ccttgccgag aaaaactcgt cgtgatgaat atacgtacat atccgggcaa gctccacctg
      301 ttcggacggc acaccgaaag caaggatttg catccggttc gcttcccaca agtcgatatg
      361 atgttttccg gtttcctctt tcctgataga aatacggggc atatcaaaac cattcttctg
      421 aaatgcttcg tacacttcct cacccacttc aaaagaagcc aatgagatac tcggaccgat
      481 acaggccacc acatcttctc cacttgtgcc aaactctttt tccatccgca acaaagtatc
      541 acgtacgatg tacgctaccg tccctctcca tccggcatga atggcggcta tggcgccatg
      601 tttcttatca tataccagca caggcacaca atctgcagta gaaatgcaaa ggcaatatcc
      661 cggctcgcgg gtaatcaaag cgtccactcc gtgcagcatc tcctgtcgtt gttgagacga
      721 agccgataaa taagcatccc cgatcagcag acaattcgtc tcatgagtct gcacaggaat
      781 caccagttct tcgggtatct gcgacattcc ttccatcaga agcgtctgat tccgccggac
      841 cttttccgcc tcgtctccac tgtaaggcgt acagttgaat gacgcataat ttccttcgct
      901 gcaccctccc tgccgggtag ttacaaaatg agaaatgttg gagtatgagc ttaacgactc
      961 ataccccaac attcttttat ctcttgtgat tgaaatcatt tttcctccca atcctcttct
     1021 tcgtattcat agtcgagatc atcgtcttcg tcgtcagcgt cttcctcata ttcatagtcg
     1081 agttcttcat cctcgcccat gtccttgagt tcctgctgca aacgggtcac gtctttcgga
     1141 cggtgaacaa tgtcttctat cttattactt tccttgttca gttcctccca cagaatgtct
     1201 ttcaacactg agattcccaa accggaaaca gaagaaatga atatatgcgg aacaccctcg
     1261 ggcaatgtcg gttcaatctc gtccatcagc tcctgatcga gcatatcgct cttcgtgata
     1321 gccagcacac gttgtttgtc cagcatttcg ggattgaacg tacgcaactc attcagcaat
     1381 acttcatact ccttgcggat atcatcgcta tccgccggaa ccatgaacaa cagcaacgag
     1441 ttacgctcga tatgacgcag aaaccgcagt cccaatcctt ttccctgact ggctccctcg
     1501 atgatgcccg gtatgtccgc catcacgaat gactttccat cgcgatagga aacaattccc
     1561 agattcggtt cgagtgtcgt aaacgggtaa tcggcaatct tcggtttcgc agccgaaatg
     1621 gcagaaagta acgtagactt tcccgcattc gggaaaccta ccagtcctac atctgccaac
     1681 agcttcagct ccatgatcac cgtcatttcc tgcatcggtt cgcccggctg cgcaaagcgc
     1741 ggagcctgac gggtagccgt cttgaaatga ctgttgccct gaccgccacg accgcctttc
     1801 agcaagatca cttcctgtcc gtcgtccgtc acatcgcaaa ggtattctcc ggtttcggcg
     1861 ttatacacta ccgttccgca gggtacttcg atcactttat ccgcaccgtc ttttccaaaa
     1921 ctacggttct tgctgcccga ttcgccatga cctgccatcg catgacggtc atacttcaag
     1981 tgaagcaatg tccagtaatt acggttaccg cgcaagataa tatggcctcc tcttccacca
     2041 tcgcccccat cgggacctcc gttaggacaa tatttctcgc gcctcatgtg cgtagagcct
     2101 cttccgccct tgcctgagcg acagtatatc tttacgtaat caacaaaatt cgattcagcc
     2161 atatttttta tttattataa tttgtctacc gcttcgcaga tatcagcgaa gataccatcc
     2221 atagtaccca gaccgttgat gtgctggtat ttcttttcgt tcttgtacca gtcgatcagc
     2281 ggagatgtct gtgaatgata tacatgcaga cgttttttga ttgtttcttc gttgtcgtca
     2341 gcacgaccgg agtctttgcc acgtttgatc agacgtacca tcagttcttc ttccggaact
     2401 tcgagatcca acattacaga aacatcctgt cctctttccg ccaacatttt ctttaatgct
     2461 tccgcctgtg caattgttct tgggaaaccg tcgaaaatta cacctttact gtctttgaag
     2521 ctatcgaata cgcttgccag aatatcaatc atcaattcat ccggaatcaa ctgaccctgg
     2581 tcgatgtaac ctttagcagt tttgcccagc tccgtgccgt tcttgatttc tgcacgcaat
     2641 acatctcctg tcgagatgtg gttgattcca tacttttcta caatacgttc gctctgcgtt
     2701 ccttttcctg aacccggagc accgaaaatt acaatgttca acatcttttt aacctataaa
     2761 ttaatttgta tttgaattta atctactaca gtataaatat cgggataatt gcgtccgaaa
     2821 ccatcataat ccaatccgta gccaacgata aaatcgttcg ggatttccat cgctacgtat
     2881 tctatgttca gattgacctt cagcttttcc ggtttcacca gcaaagaggc gatatgaatc
     2941 gcttcgggat tgcgtgtgcc cagtgtatcc agcagacgct gcatcgtcag tccggtatct
     3001 acaatatctt ccacgatcac taccgtacgt ccggcaatgt cttcattcag cccgatcact
     3061 tctttaatta ctccggtgga agtcaccccc tgataagatg ccaacttcac gaatgaaatt
     3121 tcgcacggaa tcgtgatatg cttcagcaag tcggcggtaa acatgaacga gccgttcaac
     3181 acactgagga agagcggatt cttacctgcc aaatcacgat tgatttcgtt cgctacgcga
     3241 atcacttctt tttgaatatc ctgttcctta atggaaacag taaattgctt gtcttttatc
     3301 tgtatggtat ccataaccgg tcattttaaa aaagttgtcg caaaaataca attttttatt
     3361 ctaccccgtg catcatcttc tgtaatttct tcgagagaag gaacagaatc agtgaggcaa
     3421 caccggacat aatgacgaac agcatgaaga agtcgtacat ggtagcaatc tgataaccaa
     3481 ggattgattt cacttttccg tcttcgggat agagaccgct caacatacct gcaaatttat
     3541 ttgcggtggc agtagaaaga taccaaatcc ccatcatcaa ggaggcgaaa cgtaacggac
     3601 tcaacttatt aaccatagaa agcccgatag gtgacagagc gatttctccc attgtatgaa
     3661 taaagtaaag tcctgtcagc cagatcatgc tcacctttac tcccggaata gcatctttca
     3721 ctccaaaaca gatgaagaga taaccaagag aaagcaacaa cagaccgatt gcctgcttgg
     3781 taggggaagc cggttccatg tttcgcttat tcagaaagcc ccatataccg ggcataatat
     3841 aggcaaggat caccacgaaa agcggattga atgactggaa ccacgaagcc ggcatctccc
     3901 aaccaaaaat gctgcggtca gtctgttcgg aagcgaataa tgtcagagaa gctcctgcct
     3961 gctcgtaagc tgcccagaag aaaatgacga agaaagctac gatatagatt acgaaaatac
     4021 ggctgcgttc tactttggtc aatgaaccat ccagcagaat gagcactgga aagacaatac
     4081 aagccgtaaa gatgcccaca ctaatccagt catcgctaaa ggcataacta aaaaaggcta
     4141 ttaaagcaac tgtaagagca gtaatgatga tgatattacg tactttggta cgtttgtcca
     4201 tcttcggatg tgaaatatgt tcggctttat cttccttttt ttcacgtctg gcgtcgggga
     4261 cgataccaat cggttcaccg gaaggagaga aaaggtattt attcttctga gtttcaaaga
     4321 ggacaacagt gaacagcgtc atgattccag atgcgaggaa tccccattta aagtcctgcg
     4381 gattccctgt gtctcccaag aaaccgcaaa tcaaaggagc agcgaaagaa ccgacattaa
     4441 cacccatata gaaaatggtg tatgcagcat ccaaccgttt atcccccggt tcatataatt
     4501 gcccgacaag cgaagaaacg gtaggcttaa agcaaccgtt acctaaaatc ataaatccga
     4561 gtccgccata catcagccag tgggcaaggt ttgtattgtt tagtgaagag gcactcataa
     4621 acatcaggaa ctgaccgact gccatcatca ccgctcccca aaacaccgaa cgacggatgc
     4681 cccaatattt atcggcaatg tatccgccga tcaacggagt cagatagacc agtccggtat
     4741 agctaccgta gatagaggct gccgcttctt tatcaaaaag caatgcctgc gtcagaaaga
     4801 ggataaagat ggcacgcata ccgtagtaac tgaaacgttc tgccgtgctc gttgcgaaaa
     4861 ttaggtaaag gcctttcgga tgccctttca atgaactcat gaaattatgt gtttagtagt
     4921 ttatggggtg caaaggtact aaaaagtaga ttaaatgcct caaaaaagaa gattcttatg
     4981 gaatagaaaa atacaggatg gcatgcaaga agtctcagtt acccacctta ttaagttttc
     5041 aacagtgtaa ataatcaagt ggatattctc cttaaatgtg ggtcagtcgc catttatcca
     5101 aaagtaaatt caacattctc aatactggca tagagcattc cttctttttt tctaagcagg
     5161 attttgtttt cccttgccaa ccagccgata gcaatcgcta catcctcgaa cgtcaaacct
     5221 aactcatggc acaaagtgaa catagactgt tcgccctttt catttaagat gcgccatact
     5281 ttcccggcat ttgagccaat tcttttcttt tccatcatgc aaactttaga agattaaaca
     5341 atttatattt ataatctaaa cattgtgagc acaggagaat aacgtaaagc acattactgc
     5401 actacaaaga tatcattttt ttcgaaaaaa gcaaataatc aagacattag ctgctattat
     5461 tagttacatt ctaatcattt atgccgatct ctgctaaaaa atagcacaaa taaagaaaca
     5521 gttcaattct ttttcataag tttgcagacg agaactaaac taatatcata catttaaaac
     5581 tttaactagc atgactacca aaaaactaac aggaatactt tcgttatttc tttgtattat
     5641 ttgcctcgta agctgtaatg acaatgatga caacttttct ccaatcactc tggaatatga
     5701 agatcctcaa attaagttcg acaacgagag ccgttcttac acactgactc cgttcagcaa
     5761 agaaacgaca ccactcttta tcaagggtgg agacggaact tacaaagtga ccaatgagaa
     5821 tgagaaagtg gtacaagtaa actaccacaa cggaagttta acattgaagg caaaggaaat
     5881 aggacgcgca tccatcaaga tagaagacag ctcgaataat atgtatatac tgtctgtcgt
     5941 tgtaaaatat cgtactctta ctcataaggc gtttacagca aaagtcattg tgaagggaga
     6001 cgagcttaca tctgaagaac acattgaatt aatgaacaaa gtgggcaatt catatccgat
     6061 taataaatat gtatttactt ttatgaatgc ggaagacagc aaaggaacag tagatttgta
     6121 ttattcagat aataacatga aaacaggcaa ctttgaaaaa gaacatatag tgctgaatga
     6181 agaaaacgcc attcccatca aaggtgaata caaattgcgt gagtattacc gaataacaat
     6241 taaggaagat aatggcaaag ttattgatac tttctatatt accaagaact ttctgcagtt
     6301 cctggataca agaatgaatg ctcatccgtt aattcagtac tgttttgtca gagatttaac
     6361 cgcacagtac aaacaagatt accttgcgct ggaaaatgca tatctgattc aaatagcaga
     6421 atgagaacta cactaatctt cttctttagc agagtgaata gagtatttat tatatgagca
     6481 aactccccat tagatttagc aaaaaacaat aagctattag ctaattggaa tatgcccata
     6541 gcatatttat cacaatcacc tcttccaccc ttttcctgaa ccttcgatga ataaggcgat
     6601 tgcgggtgaa agaggtgaac cggaggaata tacagtagta gaaacacgca tgggaaggtt
     6661 aacaaacagc catgaatgtt ctccggagag agtaaaagta aatgagataa caatgcttgt
     6721 tatactgcgt tacaagcatt gaaagccatc ataacaagca ttgatatcta ccataacaac
     6781 cattaatatc tgacttctca actattaata actaacacat caactattaa tacctgacaa
     6841 ctcaagtatt aatacctgaa gttccttccc aaaaagccga aaaccaaccg gaataaagga
     6901 ttaattcaga gtttttgtgt aagtttgtgc gtcgaaaact aaaagaatat cgcaatgaaa
     6961 atatttccaa gcagcagcat taagaagtta gatgcctata ccattgaaca tgaaccgatt
     7021 gcatccatag atttaatgga gcgtgccgca caggcgctga ctaaagccat caccaacaga
     7081 tggaatccgg aaacacctgt caccatcttt gccggaccgg gcaataatgg cggagacgcc
     7141 ctcgccgtcg cccgtatgat ggcagaaaaa ggatacaaga tcgaagtata tctcttcaac
     7201 acgaaaggcg aactttcgcc cgactgtcag accaacaaag aactggtaga gatgatggaa
     7261 gaagtaactt tccatgaaat aagcacccag ttcgtccccc ccacactgac atcggagcat
     7321 ctcgtgattg acggattatt cggttccgga ctcaacaaac cattgagcgg aggattcgct
     7381 gccgtcgtga aatatatcaa tgcctctccc gccatggtag tctccatcga cattccttcc
     7441 ggactgatgg gagaagaaaa tacattcaat gtaaaaagca atattatccg tgcggacgtc
     7501 actttcagcc tgcaacttcc taaactggcc ttcctcttcg ccgaaaacac agaatttgtt
     7561 ggcgaatggg agttattgga catccagctg agcgaagaag gaatcgaaga gactgaaaca
     7621 aactacgaaa tgctggaaat cgaagaaatc cgttcgctga tcaaaccacg ccagcaattc
     7681 gcccataaag gaaacttcgg acatgccctg ttgatagccg gttcgaaagg aatggcaggt
     7741 gcatcggtac tggccgcccg tgcctgtctg cgctcgggag taggtctgct gaccgtacac
     7801 gcgccgttat gcaacaacga tattctgcaa acgtccgccc ccgaagccat ggtagaaaca
     7861 gatgccagcg aaacttgctt tgccgtacct accgatacgg atgattatca agctgtcggc
     7921 atcggtccgg gactcggtcg cagcgaagaa acggaagctg ccttgataga acaactggaa
     7981 cattgccaaa ctccgacggt actggatgcc gacgcactca atattctggc caatcaccgg
     8041 catacgctta cccatctgcc gaaaggttcc atcctcaccc ctcacccgaa agagctggaa
     8101 cgcctggtcg gcaaatgtca ggactcatac gaacgactca tgaaagcctg cgaactagct
     8161 cacactgcca aagtacatat cattctgaag ggagcttatt ccgccattat cacccccgaa
     8221 ggcaaatgtt acttcaacca gaccggtaat cccggtatgg caacaggagg cagcggagat
     8281 gtactgacag gagtaatcct tgcactcctt gcgcaaggct atcctgccga agatgccgca
     8341 aagatcggta cttacattca cggattggcc ggagacatcg cccagaaaaa gcagggcatg
     8401 atcggattaa tcgcaagtga tatcgtgacc tgtctgccga cggcatggcg acttgtaagc
     8461 gaataaaagt taagaactta cggtttattc aataacttca ttaactttgt ttttcaaaat
     8521 cagctaaaaa gaaccgaata tgaaaaagtt aatcatagca acaggactac taatggcaac
     8581 ttccgcctat gcgcagaccg aagtgttgac aggagtgacg cgaggaaaag actacggagt
     8641 agtgtacgcc ctccccaaaa cccagataga aatagaaata aaagcaaaca aagtcaacta
     8701 taagccgggt gaattcagca aatatgccga ccgctacctg agactaacca acgtctctgc
     8761 cgaacccgaa gaatactggg aattgaacag cgtcaaggtg aagcctgtag gtgtaccaaa
     8821 cagcgaagcc acttatttcg tcaaactgaa agacaaaacc gtagctcctc ttatggaact
     8881 gactgaagag ggtcttatca aatctatcaa cgtcccctac agtagtaaca atgcaaagaa
     8941 tgcagcaaac aataccgttg tcccccaacg aaaagccaat ccccgcgact tcctcacaga
     9001 agaaattctg atggcaagtt ctaccgccaa gatggccgaa ctggtagcaa aggaaatcta
     9061 taatatccgc gaaagtaaaa acgcattatt acgcggacaa gcagataata tgccatcgga
     9121 cggcgcacag ctcaaaatca tgctcgacaa cctgaatctt caggaagagg ctatgaccga
     9181 aatgttctcg ggagtccgcg ataaagaaga aaagacattt actgtccgcc tcactccgga
     9241 taaagagttc gacaatgagg tagctttccg cttttcaaag aagctgggta tagttgccaa
     9301 caacgatttg gcaggcactc cattctacat cagtctgaaa gacctgaaaa cggtgaagat
     9361 tccgcaagag gacggaaaaa agaagaaaga gatggaaggc attgcttata acgtaccggg
     9421 acaggcaatg gtgacgctga cggacggcaa aaagaaattg tatgaaggag aaatacctgt
     9481 tactcagttc ggtatcatag aataccttgc tccggtatta ttcaacaaga actcgaccat
     9541 caaagtttac tttgatccgg tgaccggtgg actactgaaa gtagatagag aagaaagcaa
     9601 ataaaacctc taaaaaaaca aaacgatggg tggcgaagga catatgctcg acatgatacg
     9661 tcggctgaaa gacggcaaag aagcctcccg cttacgccgt gaacggagaa atgacaagtt
     9721 agggcgactt agaagaaaca acgaccctta tcttctgccg gatacgactc cggaagagat
     9781 ggaacgcatc atcaaggatt cggaaaagaa aaaagaaaaa gataacagct atttcgtatg
     9841 gggaacgctc atcattatgg gcgtactgat aggatgtgct gtcctcctgt gggcaatctt
     9901 tttttaatgg ataatggaaa attgataatg gataatgaac gtatgggata atattccagc
     9961 tgctcaacct cattatccat tttccattat caattatcca ttaatcaatt atccatttaa
    10021 taaatccgtc tttctgtaat tgggaaagat aggtagatac acgagactcg tagcctgctt
    10081 catgctgaaa gtggtctgcg agtttttcta taatctcacg aaccgtccgc tggccgtcta
    10141 tcaggttcca tacggccgta ccgtgttctt ccagacgcac atgaatatct ttggacattc
    10201 ctttcggcaa taaataacga ctcatccacg aacgtttaaa acgagggaag gagagcacaa
    10261 tagtctcccc ttcctgttca gctttaatat gttcgttacg acaagggatc acctccagga
    10321 ggtttatttt ctctttcgta gccatatctt ttctctttta tatcttttca gatagaatat
    10381 atactgtgat tatttctgaa tatttgcttc ttccagtccg tagcctttct tcttgttttc
    10441 cactttcagc atcaaggcaa caatcagggc aagtacaccg aacatagcaa aaatagccat
    10501 cggcaaagta taatcataag tctgtgcacc atctacaacc ggacctttgc aataagaatt
    10561 caacacccat ccgatcagca aaggcacgcc catcaatccc cagttctgta cccaaaagat
    10621 caacgcataa gccgttccca actgtttctc cggaataatc ttcggaaccg aaggccacat
    10681 tgccgaagga accaatgaga aagcaaatcc cagaataatc atgatcaccg ttgcaaacca
    10741 ccatatattc agaataggaa gagcgaacat cgtgtgtacg aaaatcagca tcaccgaccc
    10801 gatcaccatc agcgtggctc ccttaccgat acggtcatat aatgaaccga acaacggtgt
    10861 caggatgatc gcgccaatcg gcagcaatcc gggaatcgtt cccgcaagtt tcggatcaac
    10921 attgtacttc tgtaccatca aatcggccgc atacttgatg aaggggaata cagccgaata
    10981 gaacaatacg cacagtaatg cgatcagcca gaatcctttg ttggtaatga tatagacaat
    11041 gtctttcatg cggaaaggtt cttccggttc cagtccttcc gcatccagtg aagcatccag
    11101 tttcttatcg tagaaagtat agatgaagaa tgcgatggta cctacgcaca acatgacgag
    11161 acagaacaga ataggagcgg gaatattggt atggaatacg ccgctctcat ccgtagaccc
    11221 gaagaagtct gccaaaggaa cggtaagcac catggccaaa gtcgttccaa tacgcgcggt
    11281 cgccatttcc agtcccatag cgagagccat ctctttgcct ttaaaccact tcacgataat
    11341 cttcgaaacg gtgatacccg caatttcgac tcctacaccg aaaatagcat aacccaatgc
    11401 agccaatgtg acttgcatct tgaatccgaa aagcatcgca ccttccggga aagtagtagt
    11461 aatagcataa tatttcaatc cacaaccgaa caccatcaat aaacaggcac ccattccggt
    11521 gaagcgtact cccatcttat ccagaatgat accaccaaag atgagcatca gcaggaatac
    11581 attaaaccag ccataagcac tggtgaaaaa accgtaatct aaactgtccc agagaagttc
    11641 tttttcaagc atgggtttca gaggagacat aacgtctgtg aggaagtagc cgcacaacat
    11701 ggtaaaagcg actaatgcta gaacactcca acgcagcact gcggagtcat tcagcttttg
    11761 tttcaattgt tctgtcattg taatatttaa aaggagttaa taatctcgta acgggcaaca
    11821 aagttaacta attatcattt gttttactaa aaaaggagaa cattttataa gaaaaaggac
    11881 atctgaccgg atattcctgt atgaagaaga gcagaccggg cccaataata aagacaggcg
    11941 cgaactacac gtattacacg attctattag aatctcttgt aattcgcgta attcgcgcct
    12001 ataatgaaga gaacgggtca aaaagcccgt tcactcaata agtttaaacc gaatatcctg
    12061 tcactgaatt attctgctgc aggagcagga gtttcagtag ccgaagcttc cgttgctggt
    12121 gcagactctg caggagcagt agcatctgtc tgaggagcag cagtaccggt aggcatatta
    12181 tacgggttgg tttgttgttc tttctgtgct tgttccaaca atacatcttt agccgcagaa
    12241 gaagaaggaa caacgtaagc agtagcaacg ctcatcacaa ccatgaagat agccagaccc
    12301 caagttgctt tttccagaaa atctgtagtc ttgcgcacgc ccatgatagc gtttgatgaa
    12361 gaaaaaccag aagcaagtcc gcctcctttt gaattctgaa tcagcacgat gaagcacatc
    12421 agcaaggctg caatcaccat taagataatg aataataagt acatttttag ttattttgaa
    12481 ttagcgttaa taatcaattt ctccaaaaat ctgatttggt ctgcaaagta agcatttttt
    12541 tttggatatt tcaagcttaa ttttttaatt atttca
//
