LOCUS       c00050_gnlPro..        16631 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NDLLCADB_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:19:03
            Original ID  :: gnl|Prokka|NDLLCADB_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 67023
            Orig. end    :: 83654
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16631
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[77023:80581](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13558)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16631
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16631
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             341..1567
                     /locus_tag="ctg50_35"
                     /transl_table=11
                     /translation="MFFSLIVPLFLSLFYKPIAYLCGRSLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1891..4653
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.7; E-value: 6.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_36"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.6e-20, bitscore:
                     63.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWMKTMRYLKWMLVLFCLTGMTACRQDTPRFRIGVAQCSDDSWR
                     HKMNDEILREAMFYNGVSVEIRSAGDDNTKQAEDVHYFMDEGVDLLIISANEAAPMTPI
                     VEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLS
                     GSTPAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHND
                     RIAPGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLA
                     MDILEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQ
                     QVVLYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQL
                     SHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNI
                     LLRLVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTD
                     YHTLADMEKLERIYFNLLSNAFKFTPENGRIAVRLSSLCKEDKRWIRFTVANTGSMISA
                     EHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSC
                     EAVAAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHT
                     DYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTA
                     CSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCD
                     MDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARL
                     KKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             4681..5013
                     /locus_tag="ctg50_37"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4976..6262)
                     /locus_tag="ctg50_38"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLTLPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFHKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6736..7962
                     /locus_tag="ctg50_39"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKEEREKKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7959..8789
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg50_40"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8817..9677
                     /locus_tag="ctg50_41"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNAETIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPKKD"
     CDS             complement(9688..9876)
                     /locus_tag="ctg50_42"
                     /transl_table=11
                     /translation="MIGFVIWIVGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(10001..13558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_43"
                     /sec_met_domain="PFOR_II (E-value: 2.1e-18, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.3e-31, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.1e-11, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.9e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0001, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13592..14770)
                     /locus_tag="ctg50_44"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGD
                     KNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGFLY"
     CDS             14977..16131
                     /locus_tag="ctg50_45"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGAFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             16560..16631
                     /locus_tag="ctg50_46"
                     /transl_table=11
                     /translation="MKKSDMTFSPYQLELLGDFYRSNF"
ORIGIN
        1 gagcggtgca atgcccgaac ttccggttgt tctgaaagac agattgttgt agaatctctt
       61 taaatacaaa aagcaggtgt gtcaaaagta actaaactct cctccttcgg gaaggaggag
      121 tactcgtagg gggaggtggt aggtgaatac ataagctatt gatattcaac tgtgaaatat
      181 acctaccacc ccggctttca gccacccctc cttcctgaag gagggaaatt tagttacttt
      241 tgacacatct tcttttctgt ttcttatttc agtaaatatc ccccttccct gtgttttgat
      301 ttactactta atctgttaat tattagaatg ataataacag atgttctttt ctctaattgt
      361 ccccctcttt ctttccttgt tttataagcc gattgcctat ctttgcggca ggtctttaaa
      421 taataaatca aaaagagaaa actactttat gaaacacatt tcaaacttcc tcagatcaaa
      481 aagctggaac gtatttttgt ttttatatct tgctcttcct ttgtttgcgc aaaaggaata
      541 taagatcgat caggtatccg ttgtcaatgt aggcgatggc agactgttgt ttcaggaact
      601 gaaaacggaa aaagcattga atggcgaaca tcgcatcata gatggttatc attccgccta
      661 tgtgctggca tcttttaaag atggtttcta tgatggcgga tacaaagaat atgtagacaa
      721 tatattaata acagaaggaa gttataaaga aggacggaag gatggtctct tcaagattaa
      781 ctccaagttt gacggtaagc tgaaagaaga aaagtcctat aaggaaggta agctggacgg
      841 tacgagcaaa agttacttta ctaccggaaa agtggaaagt gaaagaaact tccggatggg
      901 gaaagagcac gggaagcaac tgtcgtacga atctgacggt actttgcgga aagagcataa
      961 ttacaaggac gggaagcagg taggcaaaca gtatactttt ctgaaaggta catatgattt
     1021 gtatgagacc gtttatttca atgaagaagg ttttcaggac ggtgaatatt cgtccgtgtt
     1081 tacgtttggc tcgccacgta tactgggtag ttataagaat ggaaagaaga atggtcgttg
     1141 gactactttt gctgaaagcg gcgatacgct gatgattgaa acctatctgg atggaaaaga
     1201 agatggactc catgtctcat ttgccaacgg aagtggggta aggcagaaag aatattatat
     1261 gaagaacgat cgtaaagacg gtttataccg tgaatataat ttggaaaatg gtgaattgag
     1321 atatgaagct acctatcagg ccggcagatt gcatggcaag gaacgacggc tgatagtgag
     1381 caaccgcttt gattattggg aaacttctac ctatgtgaac ggaaggcaga acggaccgtt
     1441 cgaagctcgt tatgtaaaga atgaccagct tcgtgaatgt ggggaatata agaatggtcg
     1501 ccgtgtagga cgatggaaac gctacactat tgatggtaaa ctggaaaagg aatgggatga
     1561 aaactaaccg gtagatgaaa ggtcagggca taaaaaaagg agcaacgcct tgctccaacc
     1621 tttgttaacc ttaaatctaa tactatgaaa aacacagtac aaagatacgg acttctgtga
     1681 aatctgcaaa ttatccaagt aaaacgctat gttttataac attgattaag tgtttgtttt
     1741 acgctttata cttttgttaa tactttccga tggtctgaaa gaggactgct ttccttcttt
     1801 ttagaataat aaatagctga agttagagaa ctttacagta ttatttctta tttttgttct
     1861 taattggatt acagaaagaa ctacgaaatg atgagatgga tgaagacgat gagatatctg
     1921 aagtggatgc tggtgctgtt ttgtttaacc gggatgacgg cttgccggca ggatacaccc
     1981 cgttttcgta ttggggtggc tcaatgcagc gatgattcat ggcgacataa gatgaatgat
     2041 gagattcttc gggaagcgat gttttataat ggtgtttcgg tggaaatccg ttcggcaggg
     2101 gatgataaca ctaagcaggc ggaagatgtc cattatttta tggacgaagg agtcgatctg
     2161 ctgattattt ccgctaacga agctgctcct atgactccga ttgtagaaga agcttatcag
     2221 aaaggcatcc ccgttattct tgtagaccgg aagattcttt cggataaata tactgcctat
     2281 atcggagccg ataattatga aatcggtcgt tcggtaggaa actatattgc ctccagtctg
     2341 aaagggaagg gaaatatagt agaactgaca ggattgagcg gttcgactcc tgcaatggaa
     2401 cggcatcagg gatttatggc tgccatcagt aaattcccgg atataaagct gattgataaa
     2461 gcggatgctg cttgggaacg tggtccggca gagatagaaa tggatagtat gcttcggagg
     2521 catcctaaga ttgatgctgt gtatgcccat aatgatcgta tcgctccggg tgcctatcag
     2581 gcagcaaaga tggcagggcg ggagaaggaa atgatttttg tcggcataga tgccttgccg
     2641 ggtaagggaa acgggctgga gctggttctg gacagtgtgc tggatgctac ctttatctat
     2701 ccgaccaatg gtgataaggt actgcaactg gctatggata ttctggagaa gaaaccctat
     2761 cccaaagaaa cggtgatgaa taccgctgtt gtggaccgta ccaacgcaca cgtcatgcag
     2821 ttgcagacca cacacatttc cgaactcgac aaaaagattg aaacgctcaa cggacgtatc
     2881 ggtggctatc tctctcaggt agctacacaa caggtcgttt tatacggcag tctgattatc
     2941 cttttattgg tagccggctt attattggtc gtttataaat cactccgctc aaagaatcgc
     3001 ttgaataaag aactttttaa gcagaagcaa caattggaag agcaacgtga caaactggaa
     3061 gaacagcgtg accaattgat acaactttct catcaactgg aagaagctac tcatgccaag
     3121 ctggtattct tcaccaatat ttctcacgac ttccgtactc cgttgacatt ggttgccgat
     3181 ccggtagaac atttgttggc ggacaagaca ctgagcggag atcagcaccg gatgctcatg
     3241 ctgattcagc ggaatgtgaa cattcttctg cgtctggtca atcagattct ggatttccgt
     3301 aaatatgaaa atggcaagat ggaatatact ccggttacgg tggatgtcct ttcttctttc
     3361 gaaggatgga atgagtcttt tcaggcggca gcccgtaaga agcatatcca tttttctttt
     3421 gatagtatgc cggatacgga ttatcataca ctggcagaca tggagaagct ggaacgtatt
     3481 tatttcaatc tcctgtccaa tgcctttaag tttacaccgg aaaatggaag aattgccgtt
     3541 cgtctgtctt ccctttgtaa agaggacaag cgatggatac gtttcacggt ggcaaatacc
     3601 ggttctatga tttctgccga acatatccgc aatgtattcg accgtttcta taagatcgat
     3661 atgcaccata ccggttcggg aatcggactg gcattggtaa aagccttcgt agaaatgcat
     3721 ggtggtacga tctctgtaga gagcgatgag aaacagggta cggtctttac cgttgaactg
     3781 cctgtacagt cttgcgaggc tgttgctgcc gaaccggata ccacccttgt ttctgcggat
     3841 tcccgtacaa cagatgttct attggcggaa gaggaagaac tggaaaaagg atatgactct
     3901 tccaaatcgt ccgtactgat tattgatgat aatgaggata tccgttcgta tgtccatacg
     3961 ctgttgcata cagactatac ggtgattgaa gcggcagacg gctccgaagg aatccgtaag
     4021 gctatgaagt atgttcctga cctgattatt tccgatgtga tgatgccggg cattgatggc
     4081 attgaatgtt gccgccggct gaaaagtgag ttacagacct gtcatattcc ggttattctg
     4141 ctgacggcgt gttcactgga cgaacagcgt attcagggat atgacggtgg tgccgattct
     4201 tatatttcaa agccgttcag ttcacaactg ttgctggcac gtgtccgcaa cctgatcgat
     4261 tctcaccgtc gtctgaaaca gttctttggt gacgggcaga cattggcgaa ggaagatgtt
     4321 tgcgatatgg acaaggattt tgtagaaaga ttcaagtcat tgattgaaga gaaaatggga
     4381 gactccggtt tgaatgtgga ggacttgggc aaggatatgg gactaagccg tgtgcagctt
     4441 taccgcaaga ttaaatcgtt gactaactac tctccgaatg aattgctccg tatcgcccgt
     4501 ttgaagaagg cagcttcttt gcttgcttct tcggacatga ccgtagcgga gattggttat
     4561 gaagtcggtt tcagttcacc ttcttatttc accaagtgct ataaagagca gttcggagag
     4621 agcccgacag acttcctgaa aaggaaagga tgatttcatt gagatcgtaa agagggatat
     4681 atgaaagatt ataaagtaga taaagagagt ttttccgaat cctttcggaa ggaagtgtac
     4741 gaagtcgtat cccagatacc tgtgggaaaa gtatctacct atggaggtat tgctttgctt
     4801 ttgggtgccc cccaatgttc gcggatggtg gggcgtgcat tgaaagaagt gccggatgaa
     4861 ttatccattc cttgccatag agttgtaaat tccaccggaa ggctggtacc cggttgggtg
     4921 gaacaaaaac aactcttgct ggcagaagaa gtttctttca aagctaacgg atgcgttaat
     4981 ctgaaagaac atttgtggca cgtggatgaa tgaaggatgc aaggaaggta agccatatca
     5041 tccgtatcca tacaataaag aaaacccata catgaagcca taaggtcctg gtaatgaaat
     5101 ctctgatggg aacagggacg aatatgtcga taggaacgat gcataacagc acaaaacagc
     5161 accaaaatag aatcttgtct gttgcggtac gtgttggcct gctccaatac cagagcatga
     5221 aacctgccaa tgcgataata taggtatgtt tctcggcgga gtcactcagt aatactaccc
     5281 agcccatgag aatgcccaaa gcttgggcac ggaaggcaaa agacgaccat ttgtggaaat
     5341 tccccaaaaa gagcagagtc agtagaccga gcattcctat ctgaagtgca cggaagtgtg
     5401 gcaatgtcca tgctgcaatg gggcgggcat agaaaaatga atcataagct ccggcggatt
     5461 gatgaacagc aagactatgg caccattctt cataataggg gagcaaatct gcaggagcta
     5521 ttttgattaa cggtaacgta agcaatacaa tgcccattgc aacggcatag ccaaagttac
     5581 gccatacgtg aggatagcac agcaacaatg ccagttcgaa aattccatat actttggtac
     5641 atcccgaaat catgattaac agaacagcca gaaatccacg gtctttttcc aataacgtat
     5701 aggcgaataa gaataaatag gctaccgtta tgttatactg aaatgaaagt aaactttgtc
     5761 ctaaaatcag taacagaaaa aggaacatac ggcatttctg ttgctgggtg aattgttggg
     5821 gcagcgtgaa gatcgccaca aagaacaatg aataattgaa tagattccac gcgaaaggtc
     5881 ccagccatgc aggcagatac gcaaacggag cgaacaatac cgtgaaaaca ggagaataaa
     5941 ggaagtagcg tccgtgagct tctacaaatt cggttgtgta tgggctgatg ccttgccaga
     6001 agaattgagt agcgtctgag aagaccataa agttttgatg ccgtcctcgc ataaattcga
     6061 gcagagtcac tataaaagcg agcaggaaac ctatcatgta gagattccgc cgactataga
     6121 aaaacggcat tttggggttc tttttactaa ggaactgtac ttggcttttg tcgtctagtg
     6181 tggcagtacc tgtttgtttt tcttttgttg tgtaatgaca attatccttc cccaggaaaa
     6241 ttgtaatagc cctgttgaac atataaatct agtttagtta ttgacgccaa atatacggtg
     6301 tttaggtgaa atattcaaac ttattttata tttatctgct ggtttgttct attttgctga
     6361 gtgatagggg aatattaccc ggaaactttc catatcatta caaataaagt cctctgtatg
     6421 ccccggattt tgaatataat ttgcatgttt aatctgtttt ttgtatcttt gtgccagcaa
     6481 gatactggaa cagactgttt ttatacataa aaatgctatt tttttgctat tcgttgaaag
     6541 gattatctta tcaaattcta ttcctttttt aattactcag tctgtcaata atcattttat
     6601 taattatttc gggattcatt gttatttgtc ccgtatttaa atcagaactt tatacgatat
     6661 aaagaaagat tcctgttatc gtttgttctt gtcttgctgt gtatattatt ttaataacct
     6721 aaaccatttt attgtatgag taaaatagaa attaaagatc tctatctggt ttttggcaat
     6781 gagaagcaga aggctttgaa gatgttgaaa gaaggtaaaa ctaaaagtga aatattgaaa
     6841 gcgaccggat gtacggttgc ggtgaaagat gcgaatcttt ccattaatga aggcgaaata
     6901 ttcgtcatta tggggttgtc cggtagtgga aagtccactt tactccgctg catcaaccgt
     6961 ttgatacgcc ctacttccgg agaagtgatt atcaatggaa cagacatagc caaagtgtcg
     7021 gataaagaac tgttgcagat tcgccggaaa gaactggcta tggtctttca gaacttcggt
     7081 ctgcttcctc accgttctgt cttgcataat atagctttcg gactcgaact acagggagtt
     7141 aaaaaggaag aacgggagaa gaaagcgatg gaaagtatgc aactggtggg gctgaaaggc
     7201 tacgagaatc agatggtaag tgaactgtcg ggtgggatgc agcagcgtgt cgggctggcg
     7261 cgggctttgg ccaataatcc cgaagtcctg ttgatggatg aggccttctc ggcactcgat
     7321 cctttgatcc gtgtgcagat gcaggatgaa ctgctgactt tgcagtcgaa gatgaaaaaa
     7381 acgattgtct ttattactca cgacctgagt gaagcgatta aattgggtga ccggattgct
     7441 atcatgaagg atggagaaat tgtacaaatc ggtacatcgg aagaaatcct gaccgaacct
     7501 gccaacgctt atgtagaacg atttgtggag aatgtagatc gaagcaagat tataacagct
     7561 tcctctgtta tggtagataa acccatagtg gcacgtttga agaaagaagg cccggaggtg
     7621 ctgatccgta agatgcgcga acggaatctg accgttcttc cggtagtcga ttccaataat
     7681 ctgttagtag gagaggtgcg gttgaatgac ttgctgaaac tacgaaaaga gcaaatccgc
     7741 tccatcgagt ccgtagtaag gcatgaagtt cattcagtgc tgggtgatac ggtgctggaa
     7801 gatattcttc cgttgatgac aaaaacgaac tcgccaatct gggtcgtaaa tgagaatcgg
     7861 gagtttgaag gcgtagtgcc actttcctca ttgatcatcg aagtaacggg aaaagataaa
     7921 gaagaaatta atgaaatcat tcaaaacgca atagaattat gataaatatc ggacaatata
     7981 tagaaactgc cattaattgg ctcacagaac attttgcttc cttttttgat gctctcagca
     8041 tggggatcgg aggattcata gacggttttc agcacgtact gtttggaata cctttttata
     8101 tcacaattgc agtgctggct gcgctcgcct ggtttaagtc gggtaagggg acagccgtat
     8161 ttaccctctt gggcttattg cttatttacg gcatgggctt ttgggaagaa acgatgcaga
     8221 cattggcgtt agtactttct tccacttgtc tggcattgct tttaggcgtt ccgctgggaa
     8281 tctggactgc caacagtgat cgttgtaaca agataatgcg ccctgtcctc gactttatgc
     8341 agacaatgcc tgcctttgtc tatctgattc ctgccgttct attcttcgga ttgggaactg
     8401 tgccgggagc ttttgccacc atcatctttg caatgcctcc tgtggttcgt ctgaccggcc
     8461 tgggcattcg tcaggttcct aaaaacgtag tagaagcctc ccgctctttt ggagctactc
     8521 cctggcagct tctttataag gtacaattgc ctttggcgtt gcctactatt ctgacgggaa
     8581 tcaaccagac gatcatgatg tcactttcga tggtagtgat tgccgccatg atttctgccg
     8641 gaggattggg agaaatcgtg ctgaaaggta tcacccaaat gaaaatcgga ctcggatttg
     8701 aaggcggtat cgcagtcgtg atattggcga tcgtgctgga ccgcatcact cagggcatgg
     8761 cagataacag aaaaagtaaa aagaaataag aatcacacca aagaaaggaa taatcaatga
     8821 ataagataaa aatgattgcg gcaatgttta ttgccggcat actcttaacc ttcgtttcct
     8881 gcggagacaa cggaaagagt aagaagataa gtatcgctta tgccaactgg tcggaaggga
     8941 ttgccatgac aaaccttgcc aaagcgattt ttgaagatca gggatacgat gtaaagttgc
     9001 tgaatgccga ccttgcacct atatttacct ctatctcccg taagaaagca gacgtattta
     9061 tggatgtctg gatgcctgtc actatggaag attatatgaa acaatacggg gataaactcg
     9121 aagttatcgg ggatatttat gatggtgccc gtatcgggct ggtggttccg gattacgtta
     9181 cgatcaactc gatcgaagaa ctgaacgcgg aaaaggaacg tttctccggt cagattgtcg
     9241 gtattgatgc cggagccggt attatgaaag ctaccgatca ggccatcaaa gactatggat
     9301 tggattataa actgatgact tcgagcggac ctgccatgac tgcttcccta aagaaagcga
     9361 ttgataagaa agactggatt gtcgtgacgg gatggacgcc tcactggatg ttcgaccgtt
     9421 tcaaactgaa agttcttcag gacccgaagc tgatatatgg aaatgcggaa accattcata
     9481 ccatagcgtg gaaaggtttt agcgagaaag atccttttgc tgccgaactt ctgggcaata
     9541 ttcgtctgac tgatgcggaa atcagctctt taatgactgc tctggaagag gcgcagacga
     9601 cggaaagaca ggctgcccgt caatggatgg aagaacatca ggaactggta aacagttgga
     9661 ttcctaagaa agattgataa gcaaacacta cttcaaccat cccgccattc tttctttacc
     9721 atagaagtag tagaaaagta gtcccagcca gctggtaaga acgattaata caatcgctat
     9781 aagccttttc tctacagccg catttatatt ccaaatctct atggcagctc tgaaagtcag
     9841 tatcaaaccg acaatccaaa taacaaatcc gatcatatct ttagagtttt aatgaatatc
     9901 ttcgtgagaa gtaatcgtta cttctaatat ataaacaaaa aaggcaggaa tctgtttcca
     9961 ggattcctgc cttttattat gtacaaagta tttctactta ttattcagct gtatcagctc
    10021 cccagttttc tctggcaaga cgtttgtagc tgttgtaacg ccatttagcg ttttcttcag
    10081 cagctttaaa cagttcttca gcttcagcag ggtattgttt cattacagaa gcgtaacgaa
    10141 cttcaccctt caagaaacct tggaagtctt cccagttagg ttctttgcta tccagctgga
    10201 acggattctt gccttcttct tccaaagcag ggttgtaacg ccacaagtgc cagtaaccgc
    10261 acttaacagc cttttcttct tcttcctggc tcttacccat accggctttc agaccgtggt
    10321 tgatacatgg agcgtaagcg atgatcagtg atggtcccgg atatgcttca gcttcgcgga
    10381 tggctttcag agtctgagcc tggtcagcac ccatagcaat ctgagcaaca tatacataac
    10441 cgtaagtagt agccatcaga ccgaggtctt tcttacgtac acgcttacct gcagcagcaa
    10501 acttagcgat agcgcctacc ggagtagctt tagaagactg accacctgtg ttagagtaaa
    10561 cctcagtatc caatacaagg atgttaacgt ccttaccgga agcgattaca tggtcaagac
    10621 caccgtaacc gatatcgtaa gaagcaccgt caccaccgat gatccattgg ctacgtttaa
    10681 caagatattg ttgcagatca gcgatttgct tgcagtggtt gcatttatct ttagcagctt
    10741 ctaccatcgg aatgatcttt tcagccagtt ccttagtctt ttctgcatcc agcatattgt
    10801 tgatccattc agcgaatact tctttgtatt cagctgggca gcaatcagaa gcgatagctt
    10861 cgttcattac tttcaccaga cgggcacgca ttttttcgtt agccagttcc atacccagac
    10921 caaattcaca gaagtcttcg aacaaggagt tagcccatgc aggaccgtga cccttttcgt
    10981 tcatagtgta cggagtagaa ggaactgaac ctgagtagat agaagaacat cctgtagcgt
    11041 tagcaaccat ttcacggtca ccgaacaact gagaaatcag tttcacgtac ggagtttcac
    11101 cacaaccgga gcaagcgcct gagaactcaa acaacggagt tgcgaactga gagttcttca
    11161 cgttagcctt gatgtctacc aggtgttgtt tgctcttcac gttttcagcg cagtaagtcc
    11221 agttatcagc ttcggccaac tggctttcaa ggtgtttcat ggtcaatgcc ttgccaccct
    11281 tcttcggatt acccggacag atgtcggcac agttaccgca acccagacag tcgagaacgt
    11341 ctacctgaat acggaatgtc ataccatcga atgctttacc tacagctttc agttgctcga
    11401 acttagcacc cttctgctct tcagcatcga gtacgaacgg acggatagaa gcgtgaggac
    11461 aaacgtaagc acacttgtta cactgaatac agttttcagc attccattcg ggaacgaatg
    11521 cagctacacc acgtttttcg tatttggaag taccttgata ccaagtaccg tcttcgatac
    11581 ccttgaatgc agataccggc agcaagtcac cgtcctgtgc attgatcgga cgaactactt
    11641 cgttgatgaa agcaggatca ttgttttctg cttttgcatc atccggcagg ttagcccaag
    11701 caggatcgac agtcagagtc ttgtattcac caccgcggtc tacagcagcg tagttcttgt
    11761 taacaacgtc ttcacccttc ttgccgtaag acttaacgat gaatttcttc atctgttcaa
    11821 cagcttgatc tacaggaata acgcctgtga tacggaagaa tgcagactga aggattgtat
    11881 tggtacggtt gcccagacca atttccattg caatctgagt tgcgttgata tagtatacag
    11941 agatgttgtt ctgtgcaaag tatttcttca ccttgttagg caggttctta gccagttctt
    12001 cgccttccca gatggtgttc agcaagaaag aaccgttctt acgcaaacca cgtgttacat
    12061 cgtacatgtg caggtaagcc tgaacgtgac aagcaacgaa gttcggagta tttaccaagt
    12121 aagtagaacg gatcggagta tcaccgaaac gcaggtgaga acaagtgaaa ccacccgact
    12181 tcttggagtc gtaagagaag taagcctgac agtgtttgtc ggtgttgtca ccgataatct
    12241 taacagagtt cttgttggca cctactgtac cgtcagcacc cagaccgtag aatttagctt
    12301 cgaacatacc ttcaccgccc agagcgattt cttctttctg aggaagagaa gtgaacgtaa
    12361 cgtcgtctac gataccgata gtgaagtggt tcttcggcat tggcatagcc aagttttcga
    12421 atacagagat gatctgtgcc ggagtggtat cttttgaacc cagaccgtag cgaccgccaa
    12481 cgataacagg agcattttct gcgccataga agcagtcttt aacgtcaagg taaagaggtt
    12541 cgccgttagc acccggttct tttgtacggt caagcactgc gatgctcttt gcagtcttgg
    12601 gtacagcagc caggaagtgt ttagcagaga acggacgata caagtgtacg gcaaccatac
    12661 ctactttttc gccgtttgct accaagtggt cgatagcttc gcgggcagct tcagttacag
    12721 aacccattgc gataattacg cgttctgcat cttctgcacc gtagtaatcg aacaaaccgt
    12781 atttgcggcc tgtgatcttg gaaatttcgt tcatgtattc ttctacgata gcaggaactg
    12841 cttcatagta gttattgcat gattcacgat gttggaagaa gtggtcgggg ttttcagcca
    12901 taccacgggc aaccggcttc atcggattca gtgcacgggc acggaattca gccaaagctt
    12961 cctggtcgat cagcggagcg aggtcgtcgt tttccaacat ttcgatcttc tggatttcgt
    13021 gagaagtacg gaaaccatcg aagaagttca tgaacggaac gcgtgatttg atagtagcca
    13081 gatgagcaac acctgccaaa tccataactt cctgtacaga accttctgcc aacatagcga
    13141 agccggtttg acgagctgac attacgtcct gatggtcacc gaagatacac aatgcgtgag
    13201 aagccagtgt acgagcagaa acgtggaata cacaaggcaa gaattcaccg gcaatcttgt
    13261 acatgttagg gatcatcaaa agaagaccct gagaagcagt gtaagtagta gtcaatgcac
    13321 cagcctgaag agaaccgtga actgcaccgg cagcaccacc ttcagattgc atttcctgta
    13381 ccaatactgt ttcgccgaag atgttcttac gtcctgcggc agcccattcg tctacgtact
    13441 cagccatagt cgaagaagga gtgatggggt agatagctgc tacttcagag aacatatacg
    13501 agatatgtgc tgcagcttgg ttaccatcac atgtgatgaa tttcttctgt ttagtcataa
    13561 ctaaattaaa tatttaagta aataaatctt tttagtataa gaatccgaac atccaaagag
    13621 gtatttggtt gccgcggcct atctcagcct tttgcaacgc atacgtcacg tccgggttat
    13681 tctttatttt tgtaccttcc gcacaaattt tgaacggcat cacttcgtct accatgaaag
    13741 agacgttttt atctccttta tgtaccttat ggtctttcca taaagtgtta acgaagaacg
    13801 tgtcgagtac atcctgttct tccactttca ccggataaat ggagtacatc aggttagagt
    13861 tgtgcatcat aatctttgac ggtttctttg ggaattcttc tcctttcggg taaaccagat
    13921 taatcagacg cgcgtctgcc agatacttga tatagttcat taccgtagcg cgggatgtct
    13981 gtacgtcact tgccagttgg ctcacgttcg gagctttcgg tccgtccaca gccaacaaat
    14041 atagtaattt ttttatcttt gaaagatatt tcagctcaat ttgtttgatc agcaagatat
    14101 ccacttctac catcatgttc attgttttca gcagattctc cgagaaatta cgtttttcaa
    14161 ggaagaaagg gtagaaacca tgatgcaggt aatcctgaaa ataatccagc ggtcgtactt
    14221 tggaaagtac tcctttggct atctgttcat gtgtactgag gatttcttcg aggctgtatg
    14281 cccggaattt cattcctgtc tgcaggttca gaaattcacg gaaagagaat ccgcgcaggt
    14341 tataactttt cgcaatgtca cgcaattcga ggttttcctc tttgagtcgc atgacggaag
    14401 aaccggtgaa gacaatcttc aggctgggga aacggtcata gcacattcgt agctctttgc
    14461 tccattcggg atgtttgaac acctggtcga tcagcagtac ttttccgcca cgtttctgaa
    14521 actcgttggc gaagtcaaca aggctgtgac cggagaaata aaagttgttc atattgatga
    14581 acagacagga acggtcggtg ccgaatttct ctttggcgta ctgcaggagg aaagtggttt
    14641 ttcctacgcc acgtgtccct ttgataccaa tcagacggtc actccagtcg atctcgtcca
    14701 taagatcgcg gcgaacgggg gcattggtgt gctcaacgag gtaggcgtgt gtgcgataga
    14761 atgattccat ttcgtttctt tgtttttcgg ctggcaaata tagtgctttt tttaggattt
    14821 gcaaagtaga gatagcaaaa atgtgcttta atttataagt ttctctttat tgtgtaagtt
    14881 cctgattatt tcctgtatat atttgcagaa taatgtgttg aatccatctt tgacatgacg
    14941 aaaagacctg tttatatatt caatccggag catgatatgg cgttggcaag cggtgagacg
    15001 aactatatgg cgccggcttc cgcccgacag atggcgagtg acctggcgtt gcttcctatg
    15061 tggtatgccg aagcgggaag tgcggtgctt gcaccgtctg cttataatgc ggacttcctg
    15121 aaaacaaaga gtgaactttt gggcatggat gtggccttgt tgacggaacc ggaagtggct
    15181 gacggtaaag accggaagtt ctctccgtgg gggtgggacc ctgctttgcg gaagcgtttg
    15241 atgacattgg gggcagatca gacggagctg ccttctgcgg attatatgaa tattctgaga
    15301 gagcattcgc atcgtctgca ggcggtaaag ttgttgcctg ggttgcggtt gaatgaatac
    15361 ttctgtggag aatcttttta tttgagtact ttggcggagt gcagtgcgtt cgtcgaaggg
    15421 cgggaagcgt gcttgttaaa agctccgctt tccggaagcg ggaaaggatt gaattggtgt
    15481 aaaggcatat ttactacttt tatttccggt tggtgtgccc gtgtcgctgc ttctcagggt
    15541 ggggtggtag gcgaacctat atataataag gtggaagatt tcgctatgga gttttatgct
    15601 gacgggagag gaagggttgt ttttgccgga tattcggtct tccacacggg tgggagtggg
    15661 atgtatgcag ggaatgactt gctgtctgac gagaagattc tgcagaaact atcggcttat
    15721 gtgccacaag aagaatttat caggctgcgg actcgtttgg aagaagaatt gtcagctttg
    15781 ttcggtggct tttatcatgg atacttggga gtggatatga tgatttgtca ttttccggat
    15841 gaagcgcctg tttaccggat tcatccttgt gtcgaaatta atctgcgaat gaatatgggg
    15901 gtggtggcat ggctcttgac ggatcgttat ttggctgcgg atgcggaagg agcttttcgg
    15961 attgattatt atcctttagc cggtcaggct ttggaggaac atcggcagat gtcggcttcg
    16021 ttccctttgt ccgtagagaa taatcgggtg tgtgccggat atttgccgtt agtaccggtg
    16081 acgcctcaaa gccggtatcg tgcgtttctt ttgcttactc tcccccagtg aaaaagatag
    16141 tgcttttgct ctcatgctct aacagttcgt ctgtatccct ttattcatcg atgttttagc
    16201 tgttagagat ccagtggtag cagagtgaga gcaaggactt gctctcactc tgcatcgtcc
    16261 tgataaatac cgtttttact gtgttattct ttgatttaca ggatgttaat atctgatatc
    16321 tcaactgtta acgtttgatt tctcagatat taataattga gaaatcaagt attaaggact
    16381 gataatttat gtattattga ctgatatatg atttaatgtt ttcagagaga gcagtactat
    16441 tgaagtagct gatgcgttca atgtgattgg aacatgcggt taagtcaatc aaatcaacag
    16501 tagttgtctt accctggatt tggttgacta ctataagtat caactaaaat gaataaaaga
    16561 tgaaaaagag tgacatgacc tttagtcctt atcagcttga acttcttggc gatttctatc
    16621 gttcgaattt c
//
