LOCUS       gnlProkkaFDKCFOPL_104  14977 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDKCFOPL_104.
ACCESSION   gnlProkkaFDKCFOPL_104
VERSION     gnlProkkaFDKCFOPL_104
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:49:45
            Original ID  :: gnl|Prokka|FDKCFOPL_104
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14977
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1191
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 382.1; E-value:
                     6.6e-116)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="MTEALSRAIDVAIQVAPTDLSVLITGESGVGKESFPQIIHQYSRR
                     KHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFGEADGGTIFLDEVGELPL
                     PTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAIAEGRFREDLYYRLNTVP
                     IQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKILLAYPWPGNVRQLKNIT
                     EQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFESEREILYSVLFDMRQEV
                     AELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAIIHAVQQPSVCPKEDDDDI
                     QDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEYELD"
     protocluster    1..14977
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4629:4977]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4630..4977
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14977
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14977
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             1178..1705
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MNWIKKIARPLILVVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1710..2504
                     /locus_tag="ctg104_3"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2511..2906
                     /locus_tag="ctg104_4"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             3197..4585
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 89.1; E-value: 3.9e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCELKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             4630..4977
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_6"
                     /sec_met_domain="PF05402 (E-value: 2.2e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.2e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(4967..5254)
                     /locus_tag="ctg104_7"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(5276..6340)
                     /locus_tag="ctg104_8"
                     /transl_table=11
                     /translation="MKKFIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(6414..7925)
                     /locus_tag="ctg104_9"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTSEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQAGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             complement(8391..8951)
                     /locus_tag="ctg104_10"
                     /transl_table=11
                     /translation="MKAKEIGRASIKIEDSSNNMYILSVVVKYRTLTHKAFTAKVIVKG
                     DELTSEEHTELMNKVGNSYPINKYVFTFMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVL
                     DEENAIPIKGEYKLSEYYRITIKEDNGKVIDTFYITKNFLPLLNTRMNAHPLIQYCFVR
                     DLTAQYKQDYLALENAYLIQIAE"
     CDS             9497..9721
                     /locus_tag="ctg104_11"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             9914..11458
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_12"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11500..12036
                     /locus_tag="ctg104_13"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             12070..12639
                     /locus_tag="ctg104_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             12652..13818
                     /locus_tag="ctg104_15"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             13842..14627
                     /locus_tag="ctg104_16"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEVEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
ORIGIN
        1 aataccgagg ctttatcacg tgccatagat gttgccattc aggtagctcc taccgatttg
       61 tctgtgctga ttaccggaga aagtggagtc ggaaaagaaa gttttccaca gatcattcat
      121 caatatagcc ggagaaagca tgggcagtat attgctgtca actgtggtgc cataccggaa
      181 ggtacgatcg attccgaact gttcggacac gagaaaggag catttaccgg tgctattggt
      241 gagcggaaag gatattttgg agaagctgac ggtggaacta tcttccttga tgaagtggga
      301 gagttgccgt tgcctacaca ggcgcgtctg ctccgtgtac ttgaaagcgg tgaatttatc
      361 aaggtaggtt catccaaagt acaaaagacg gatgtacgta ttgtggcagc taccaacgtg
      421 aacctgacac aagccattgc cgaaggacgc ttccgggaag atttgtatta tcggttgaac
      481 acggtgccta ttcagatacc acctttgcgt gagcgtggag atgatgtgct gttgttgttc
      541 cgtaagtttg ccgcagactt tgccgaaaag taccggatgc cggctatcca gctgacggaa
      601 gatgccaaga agatattgct tgcttatccg tggccgggaa acgtccggca gttgaagaac
      661 atcacagagc agatttcgat tatagaaaca aaccgtgaga taacggctgc gattctgcag
      721 acctatcttc cggcacagaa tacccaacgc cttccggcac tgttcggcac acgcgagagc
      781 aagagctttg agagcgaacg cgaaatacta tattctgtct tgttcgatat gcgtcaggaa
      841 gtggcggaac tgaagaagat ggtgcacaat atgatggctg aacgtgcggg acaagtcgga
      901 cagatgggac aggtagtagc tactccggta gtgacaacga cgcaccaacc ttccgtgccg
      961 gccattatcc atgctgtgca gcaaccgtct gtttgtccca aagaagacga tgacgatatt
     1021 caggacacgg aagaatatgt agaagaaacc ctttcgctcg atgaagtgga aaaagaaatg
     1081 atacgtaaag cgcttgagag gcatcatggt aagcggaaaa gtgcggcgaa ggatctgaat
     1141 atctccgagc gtacccttta cagaaaaata aaagaatatg aattggatta agaaaatagc
     1201 acgaccgctg atattggttg ttttaccggc agtcatcatc gcctgtagtg tgtcctataa
     1261 gtttaatggc tcctctatca attacgataa ggtgaagact atttcgattg ctgatttccc
     1321 gattaagtcg gagtatgtgt atgctccgct ggctaccaag ttcaatgaag acctgaaaga
     1381 tatcttcatc agacagaccc gtctgcaact gctgaaaccg aaccagaatg cggatctgca
     1441 gattgacggt gaaattacgg gctacaacca gtataaccag gcagtgtctg ccgatggtta
     1501 ctcttcggaa acgaagctga ccatcacggt caatgtacgc tttgtcaaca acacaaatca
     1561 cgccgaagac ttcgaacaac aattctcagc tttccgtacc tatgattcca gccagctgct
     1621 gacggccgta caggatggat taatagcgga aatgagtaaa gagataaccg accaaatatt
     1681 taatgcaact gtagcaaact ggtaatttaa tgacttctgt taacttgcaa caatggattc
     1741 agcatcccga gacgctgaat agggatactt tgtacgaact gcgcaaccag ctcgcgaggt
     1801 atccgtattt tcagtcgctc cggttgttgt atctcaagaa cctgtatatt ctccacgaca
     1861 ttaatttcgg tgcggaactg cggaaagccg ttctgtatat tgccgaccga cggaaactgt
     1921 ttcatctgat cgaaggcgaa cgcttcgctg tcgaatccca gaagaaaggg ttgcctctct
     1981 ctgaagtatt gaaagatgag cctaccgtcg accggacact ggctctgatc gatgctttcc
     2041 tttcgacggc tcccgaagaa gtaaccagtc agacaagctt tgattactct atggactata
     2101 cggcatacct tctcgaagag acacctgtcg ccgacgagcc ggcagaggca atgcccaagc
     2161 tgaaaggaca cgagctgatt gacaacttta tcgaaaaaag cgagactgat ccagtcgtat
     2221 acctgaaacc tttgagggaa gaagagaaag caaaggcagc ttcttccgct gaaacaaacg
     2281 aaacgggcag aacagacgaa acaactgaaa ccaacaccat agaagaggaa gatgacagct
     2341 gtttcacaga aactttggcc aaaatctacg taaaacagca acgatattcg aaagctcttg
     2401 aaataattaa aaaattaagc ttgaaatatc caaaaaaaaa tgcttacttt gcagaccaaa
     2461 tcagattttt ggagaaattg attattaacg ctaattcaaa ataactaaaa atgtacttat
     2521 tattcattat cttaatggtg attgcagcct tgctgatgtg cttcatcgtg ctgattcaga
     2581 attcaaaagg aggcggactt gcttctggtt tttcttcatc aaacgctatc atgggcgtgc
     2641 gcaagactac agattttctg gaaaaagcaa cttggggtct ggctatcttc atggttgtga
     2701 tgagcgttgc tactgcttac gttgttcctt cttcttctgc agctaaagat gtattgttgg
     2761 aacaagcaca gaaagaacaa caaaccaacc cgtataatat gcctaccggt actgctgctc
     2821 ctcagacaga tgctactgct cctgcagagt ctgcaccagc aacggaagct ccggctactg
     2881 aaactcctgc tcctgcagca gaataattca gtgacaggat attcggttta aacttattga
     2941 gtgaacgggc tttttgaccc gttctcttca ttataggcgc gaattacgcg aattacaaga
     3001 gattctaata gaatcgtgta atacgtgtag ttcgcgcctg tctttattat tgggcccggt
     3061 ctgctcttct tcatacagga atatccggtc agatgtcctt tttcttataa aatgttctcc
     3121 ttttttagta aaacaaatga taattagtta actttgttgc ccgttacgag attattaact
     3181 ccttttaaat attacaatga cagaacaatt gaaacaaaag ctgaatgact ccgcagtgct
     3241 gcgttggagt gttctagcat tagtcgcttt taccatgttg tgcggctact tcctcacaga
     3301 cgttatgtct cctctgaaac ccatgcttga aaaagaactt ctctgggaca gtttagatta
     3361 cggttttttc accagtgctt atggctggtt taatgtattc ctgctgatgc tcatctttgg
     3421 tggtatcatt ctggataaga tgggagtacg cttcaccgga atgggtgcct gtttattgat
     3481 ggtgttcggt tgtgaattga aatattatgc tattactact actttcccgg aaggtgcgat
     3541 gcttttcgga ttcaagatgc aagtcacatt ggctgcattg ggttatgcta ttttcggtgt
     3601 aggagtcgaa attgcgggta tcaccgtttc gaagattatc gtgaagtggt ttaaaggcaa
     3661 agagatggct ctcgctatgg gactggaaat ggcgaccgcg cgtattggaa cgactttggc
     3721 catggtgctt accgttcctt tggcagactt cttcgggtct acggatgaga gcggcgtatt
     3781 ccataccaat attcccgctc cgattctgtt ctgtctcgtc atgttgtgcg taggtaccat
     3841 cgcattcttc atctatactt tctacgataa gaaactggat gcttcactgg atgcggaagg
     3901 actggaaccg gaagaacctt tccgcatgaa agacattgtc tatatcatta ccaacaaagg
     3961 attctggctg atcgcattac tgtgcgtatt gttctattcg gctgtattcc ccttcatcaa
     4021 gtatgcggcc gatttgatgg tacagaagta caatgttgat ccgaaacttg cgggaacgat
     4081 tcccggattg ctgccgattg gcgcgatcat cctgacaccg ttgttcggtt cattgtatga
     4141 ccgtatcggt aagggagcca cgctgatggt gatcgggtcg gtgatgctga ttttcgtaca
     4201 cacgatgttc gctcttccta ttctgaatat atggtggttt gcaacggtga tcatgattat
     4261 tctgggattt gctttctcat tggttccttc ggcaatgtgg ccttcggttc cgaagattat
     4321 tccggagaaa cagttgggaa cggcttatgc gttgatcttt tgggtacaga actggggatt
     4381 gatgggcgtg cctttgctga tcggatgggt gttgaactct tattgcaaag gtccggttgt
     4441 agatggtgca cagacttatg attatacctt gccgatggct atttttgcta tgttcggtgt
     4501 acttgccctg attgttgcct tgatgctgaa agtggaaaac aagaagaaag gctacggact
     4561 ggaagaagca aatattcaga aataatcaca gtatatattc tatctgaaaa gatataaaag
     4621 agaaaagata tggctacgaa agagaaaata aacctcctgg aggtgatccc ttgtcgtaac
     4681 gaacatatta aagctgaaca ggaaggggag actattgtgc tctccttccc tcgttttaaa
     4741 cgttcgtgga tgagtcgtta tttattgccg aaaggaatgt ccaaagatat tcatgtgcgt
     4801 ctggaagaac acggtacggc tgtatggaac ctgatagacg ggcagcggac ggttcgtgag
     4861 attatagaaa aactcgcaga ccactttcaa tatgaagcag gctacgagtc tcgtgtatct
     4921 acctatcttt cccaattaca gaaagacgga tttattaaat ggataattat ccattaaaaa
     4981 agattgccca caggaggaca gcacatccta tcagtacgcc cataatgatg agcgttcccc
     5041 atacgaaata gctgttatct ttttcttttt tcttttccga atccttgatg atgcgttcca
     5101 tctcttccgg agtcgtatcc ggcagaagat aagggtcgtt gtttcttcta agtcgcccta
     5161 acttgtcatt tctccgttca cggcgtaagc gggaggcttc tttgccgtct ttcagccgac
     5221 gtatcatgtc gagcatatgt ccttcgccac ccatcgtttt gtttttttag aggttttatt
     5281 tgctttcttc tctatctact ttcagtagtc caccggtcac cggatcaaag taaactttga
     5341 tggtcgagtt cttgttgaat aataccggag caaggtattc tatgataccg aactgagtaa
     5401 caggtatttc tccttcatac aatttctttt tgccgtccgt cagcgtcacc attgcctgtc
     5461 ccggtacgtt ataagcaatg ccttccatct ctttcttctt tttcccgtcc tcttgcggaa
     5521 tcttcaccgt tttcaggtct ttcagactga tgtagaatgg agtgcctgcc aaatcgttgt
     5581 tggcaactat acctagcttc tttgaaaagc ggaaagctac ctcattgtcg aattccttat
     5641 ccggagtgag gcggacagta aatgtctttt cttctttatt gcggactccc gaaaacatct
     5701 cggtcatggc ttcttcctga agattcaggt tgtcgagcat gattttgagc tgtgcgccgt
     5761 ccgaaggcat attatctgct tgtccgcgca ataatgcgtt tttactttcg cggatattat
     5821 agatttcctt tgctaccaat tcggccatct tggcggtgga acttgccatc agaatttctt
     5881 ctgtgagaaa gtcgcgggga ttggcttttc gttggggagc aacggcattg tttgctgcat
     5941 tctttgcatt gttgctgctg taggggacgt tgattgattt gataagaccc tcttcagtca
     6001 gttccataag aggagctacg gttttgtctt tcagtttgac gaaataagta gcttcgctgt
     6061 ttggtacacc tacaggtttc actttgacac tgttcagttc ccagtattct tcgggttcgg
     6121 cagagacgtt ggtcagtctc aggtagcggt cggcgtattt gctgaattca cccggcttat
     6181 agttgacttt gtttgctttt atttctattt ctatctgggt tttggggagg gcgtacacta
     6241 ctccgtagtc ttttcctcgc gtcactcctg tcagcacttc ggtctgcgca taggcggaag
     6301 ttgccattag tagtcctgtt gctatgataa actttttcat attcggttct ttttagctga
     6361 ttttgaaaaa caaagttaat gaagttattg aataaaccgt aagttcttaa cttttattcg
     6421 cttacaagtc gccatgccgt cggcagacag gtgacgatat cacttgcgat taatccgatc
     6481 atgccctgtt ttttctgggc gatgtctccg gccaatccgt gaatgtaagt accgatcttt
     6541 gcggcgtctt cggcgggata gccttgcgca aggagtgcaa ggattactcc tgtcagtaca
     6601 tctccgctgc ctcctgttgc cataccggga ttaccggcct ggttgaagta acatttgcct
     6661 tcgggggtga taatggcgga ataagctccc ttcagaatga tatgtacttt ggcagtgtgc
     6721 gccagttcgc aggctttcat cagtcgttcg tatgagtcct gacatttgcc gaccaggcgt
     6781 tccagctctt tcgggtgagg ggtgaggatg gaacctttcg gcagatgggt gagcgtatgc
     6841 cggtgattgg ccagaatatt gagtgcgtcg gcatccagta ccgtcggagt ctgacaatgt
     6901 tccagttgtt ctatcagggc ggcttccgtt tcctcgctgc gaccgagtcc cggaccgatg
     6961 ccgacagctt ggtaatcgtc cgtatcggta ggtacggcaa agcatgtttc gctgacatct
     7021 gtttctacca tggcttcggg ggcggacgtt tgcaaaatat cgttgttgca taacggcgcg
     7081 tgtaccgtca gcagacctac tcccgatcgc agacaggcac gggcggccag taccgatgca
     7141 cctgccattc cttttgagcc ggctatcagc agggcatgtc cgaagtttcc tttatgggcg
     7201 aattgttggc gtggtttgat cagtgaacgg atttcttcga tttccagcat ttcgtagttt
     7261 gtttcagtct cttcgattcc ttcttcgctc agctggatgt ccaataactc ccattcgcca
     7321 acaaattctg tattttcggc aaagaggaag gccagtttag gaagttgcag gctgaaagtg
     7381 acgtccgcac ggataatatt gctttttaca ttgaatgtat tttcttctcc catcagtccg
     7441 gaagggatgt cgatggagac taccatggcg ggagaggcat tgatatattt cacaacggca
     7501 gcgaatcctc cgctcaatgg tttgttgagt ccggaaccga ataatccgtc gatcacgaga
     7561 tgctccgatg tcagtgtggg cggtacgaac tgggtgctga tttcatggaa agttacttct
     7621 tccatcatct ctaccagttc tttgttggtc tgacagtcgg gcgaaagttc gcctttcgtg
     7681 ttgaagagat atacttcgat cttgtatcct ttttccgcca tcatgcgggc gatggcgagg
     7741 gcgtctccgc cattattgcc cggtccggca aagatggtga caggtgtttc cggattccat
     7801 ctgttggtga tggctttagt cagcgcctgt gcggcacgtt ccattaaatc tatggatgca
     7861 atcggttcat gttcaatggt ataggcatct aacttcttaa tgctgctgct tggaaatatt
     7921 ttcattgcga tattctttta gttttcgacg cacaaactta cacaaaaact ctgaattaat
     7981 cctttattcc ggttggtttt cggctttttg ggaaggaact tcaggtatta atacttgagt
     8041 tgtcaggtat taatagttga tgtgtcagtt attaatagtt gagaagtcag atattaatga
     8101 ttgttatctc atttactttt actctctccg gagaacattc atggctgttt gttaaccttc
     8161 ccatgcgtgt ttctactact gtatattcct ctggttcacc tctttcaccc gcaatcgcct
     8221 tattcatcaa aggttcagga aaagggtgga agaggtgatt gtgataaata tgctatgggc
     8281 atattcttga ttagctaata gcttattgtt ttttgctaaa tctaatgggg agtttgctca
     8341 tataataaat actctattca ctctgctaaa gaagaaaatc agtgtagttc tcattctgct
     8401 atttgaatca gatatgcatt ttccagtgca aggtaatctt gtttgtactg tgcggttaaa
     8461 tctctgacaa aacagtactg aattaacgga tgagcattca ttcttgtatt gaggagtggt
     8521 agaaagttct tggtaatata gaaagtatca ataactttgc cattatcttc tttgattgtt
     8581 atacggtaat actcactcaa tttgtattca cctttgatgg gaatggcatt ttcttcatcc
     8641 agcactatat gttctttttc aaagttgcct gttttcatgt tattatctga ataatacaaa
     8701 tctactgttc ctttgctgtc ttccgcattc ataaaagtaa atacatattt attaatcgga
     8761 tatgaattgc ccactttgtt cattaactca gtgtgttctt cagatgtaag ctcgtctccc
     8821 ttcacaatga cttttgctgt aaacgcctta tgagtaagag tacgatattt tacaacgaca
     8881 gacagtatat acatattatt cgaactgtct tctatcttga tggatgcgcg tcctatttcc
     8941 tttgccttca atgttaaact tccgttgtgg tagtttactt gtaccacttt ctcattctca
     9001 ttggtcactt tgtaagttcc gtctccaccc ttgatgaaga gtggtgtcgt ttctttgctg
     9061 aacggagtca gtgtgtaaga acggctctcg ttgtcgaact taatttgagg atcttcatat
     9121 tccagagtga ttggagaaaa gttgtcatca ttgtcattac agctcacgag gcaaataata
     9181 caaagaaata acgaaagtat tcctgttagt tttttggtag tcatgctaat taaagtttta
     9241 aatgtgcgat attagtttag ttctcgtctg caaacttatg aaaaagaatt gaactgtttc
     9301 tttatttgtg ctatttttta gcagagatcg gcataaatga ttagaatgta actaataata
     9361 gcagctaatg ctttgattat ttgctttttt cgagaaaaat gatatctttg tagtgcagta
     9421 atgtgcttta cgttattctc ctgtgctcac aatgtttaga ttataaatat aaattgttta
     9481 atcttctaaa gtttgcatga tggaaaagaa aagaattggc tcaaatgccg ggaaagtatg
     9541 gcgcatctta aatgaaaagg gcgaacagtc tatgttcact ttgtgccatg agttaggttt
     9601 gacgttcgag gatgtagcga ttgctatcgg ttggctggca agggaaaaca aaatcctgct
     9661 tagaaaaaaa gaaggaatgc tctatgccag tattgagaat gttgaattta cctttggata
     9721 aatggggact gacccacatt taaggagaat atccacttga ttatttacac tgttgaaaac
     9781 ataataaggt gggtaactga gacttcttgc acgccatcct gtatttttct attccataag
     9841 aatcttcttt tttgaggcat ttaatctact ttttagtacc tttgcacccc ataaactact
     9901 aaacacataa ttcatgagtt cattgaaagg gcacccgaaa ggcctttacc taattttcgc
     9961 aacgagcacg gcagaacgtt tcagttacta cggtatgcgt gctatcttta tcctctttct
    10021 gacgcaggca ttgctttttg ataaagaagc ggcggcctct atctacggta gctacaccgg
    10081 actggtctat ctgactccgt tgatcggcgg atacattgcc gataaatatt ggggcatccg
    10141 tcgttcggta ttttggggag cggtgatgat ggcagtcgga caattcctga tgtttatgag
    10201 tgcctcttca ctgaacaata cagaccttgc ccactggctg atgtatggcg ggctcggatt
    10261 catgatttta ggtaacggtt gctttaagcc taccgtttct tcgctcgtcg ggcaattata
    10321 tgaacccggg gacaaacggt tggatgctgc atacaccatt ttctatatgg gtgttaatgt
    10381 aggttctttc gctgctcctt tgatttgcgg tttcttggga gacacaggga atccgcagga
    10441 ctttaaatgg ggattcctcg catccggaat catgacgctg ttcactgttg tcctctttga
    10501 aactcagaag aataaatacc ttttctctcc ttccggtgaa ccgattggta tcgtccccga
    10561 cgccagacgt gaaaaaaagg aggataaagc cgaacatatt tcacatccga agatggacaa
    10621 acgtaccaaa gtacgtaata tcatcatcat tactgccctt acagttgcct taatagcttt
    10681 ttttagctat gcctttagcg atgactggat tagtgtgggt atctttacgg catgtattgt
    10741 ctttccagtg ctcattctgc tggatggttc attgaccaaa gtagaacgta gccgtatttt
    10801 cgtaatctat atcgtagctt tcttcgtcat tttcttctgg gcagcttacg agcaggcagg
    10861 agcttctctg acattattcg cttccgaaca gactgaccgc agcattttcg gctgggagat
    10921 gccggcttcg tggttccagt cattcaatcc gctttttgta gtgatccttg cctatattat
    10981 gcccggtata tggagctttc tgaataagcg aaacatggaa ccggcttccc ctaccaaaca
    11041 ggcaatcggt ctgttactgc tttctcttgg ttatctcttc atctgttttg gagtgaaaga
    11101 tgctattcca ggagtaaagg tgagcatgat ctggctgaca gggctttact ttattcatac
    11161 aatgggagaa atcgctctgt cacctatcgg gctttctatg gttaataagt tgagtccgtt
    11221 acgtttcgcc tccttgatga tggggatctg gtatctttct accgccaccg caaataaatt
    11281 tgcaggtatg ctgagcggcc tctatcccga agacggaaaa gtgaaatcaa tccttggtta
    11341 tcagatcgct accatgtacg acttcttcat gctgttcgtc attatgtccg gtgttgcctc
    11401 actgattctg ttccttctct cgaagaaatt acagaagatg atgcacgggg tagaataaaa
    11461 aattgtattt ttgcgacaac ttttttaaaa tgaccggtta tggataccat acagataaaa
    11521 gacaagcaat ttactgtttc cattaaggaa caggatattc aaaaagaagt gattcgcgta
    11581 gcgaacgaaa tcaatcgtga tttggcaggt aagaatccgc tcttcctcag tgtgttgaac
    11641 ggctcgttca tgtttaccgc cgacttgctg aagcatatta cgattccgtg cgaaatttca
    11701 ttcgtgaagt tggcatctta tcagggggtg acttccaccg gagtaattaa agaagtgatc
    11761 gggctgaatg aagacattgc cggacgtacg gtagtgatcg tagaagatat tgtagatacc
    11821 ggactgacga tgcagcgtct gctggataca ctgggcacac gcaaccccga agcgattcat
    11881 atcgcctctt tgctggtgaa accggaaaag ctgaaggtca atctgaacat agaatacgta
    11941 gcgatggaaa taccgaatga ttttatcgtt ggctacggat tggattatga tggtttcgga
    12001 cgcaattatc ccgatattta tactgtagta gattaaattc aaatacaaat taatttttag
    12061 gttaaaaaga tgttgaacat tgtaattttc ggtgctccgg gttcaggaaa aggaacgcag
    12121 agcgaacgta ttgtagaaaa gtatggaatc aaccacatct cgacaggaga tgtattgcgt
    12181 gcagaaatca agaacggcac ggaactgggc aaaactgcta aaggttacat cgaccagggg
    12241 cagttgattc cggatgaatt gatgattgat attctggcaa gcgtattcga tagcttcaaa
    12301 gacagcaaag gtgtaatttt cgacggtttc ccaagaacaa ttgcacaggc ggaagcatta
    12361 aagaagatgt tggcggaaag aggacaggat gtttctgtaa tgttggatct cgaagttccg
    12421 gaagatgaac tgatggtacg tctgatcaaa cgtggcaaag actccggtcg tgccgacgac
    12481 aacgaagaaa caatcaaaaa acgtctgcat gtatatcatt cacagacatc tccgctgatt
    12541 gactggtaca agaacgaaaa gaaataccag catatcaacg gtctgggtac tatggatggt
    12601 atcttcgctg atatctgcga agcagtagac aaattgtaat aaataaaaaa tatggctgaa
    12661 tcgaattttg ttgattacgt aaagatatac tgtcgctcag gcaagggcgg aagaggctct
    12721 acgcacatga ggcgcgagaa atattgtcct aacggaggtc ccgatggggg cgatggtgga
    12781 agaggaggcc atattatctt gcgcggtaac cgtaattact ggacattgct tcacttgaag
    12841 tatgaccgtc acgcgatggc aggtcatggc gaatcgggca gcaagaaccg tagtttcgga
    12901 aaagacggtg cggataaagt gatcgaggta ccctgtggaa cggtagtgta taatgccgaa
    12961 accggagaat acctttgcga tgtgacggac gacggacagg aagtgatctt gctgaaaggc
    13021 ggtcgtggcg gtcagggtaa cagtcatttc aagacggcta cccgtcaggc tccgcgcttt
    13081 gcgcagccgg gcgaaccgat gcaggaaatg acggtgatca tggagctgaa actgttggca
    13141 gatgtaggac tggtaggttt cccgaatgcg ggaaagtcta cgttgctttc tgccatttcg
    13201 gctgcgaaac cgaagattgc cgattacccg tttacgacac tcgaaccgaa tctgggaatt
    13261 gtttcctatc gcgatggaaa gtcattcgtg atggcggaca taccgggcat catcgaggga
    13321 gccagtcagg gaaaaggatt gggactgcgg tttctgcgtc atatcgagcg taactcgttg
    13381 ctgttgttca tggttccggc agatagcgat gatatccgca aggagtatga agtattgctg
    13441 aatgagttgc gtacgttcaa tcccgaaatg ctggacaaac aacgtgtgct ggctatcacg
    13501 aagagcgata tgctcgatca ggagctgatg gacgagattg aaccgacatt gcccgagggt
    13561 gttccgcata tattcatttc ttctgtttcc ggtttgggaa tctcagtgtt gaaagacatt
    13621 ctgtgggagg aactgaacaa ggaaagtaat aagatagaag acattgttca ccgtccgaaa
    13681 gacgtgaccc gtctgcagca ggaactcaag gacatgggcg aggatgaaga actcgactat
    13741 gaatatgagg aagacgctga cgacgacgat gatgatctcg actacgaata cgaagaagag
    13801 gattgggaag aaaaatgatt tcaatcacaa gagataaaag aatgttgggg tatgagtcgt
    13861 taagctcata ctccaacatt tctcattttg taactacccg gcagggaggg tgcagcgaag
    13921 gaaattatgc gtcattcaac tgtacgccct acagtggaga cgaggtggaa aaggtccggc
    13981 ggaatcaaac gcttctgatg gaaggaatgt cgcagacacc cgaagaactg gtgattcctg
    14041 tgcagactca tgagacgaat tgcctgctga tcggggatgc ttatttatcg gcttcgtctc
    14101 aacaacgaca ggagatgctg cacggagtgg atgctttgat tacccgcgag ccgggatatt
    14161 gcctttgcat ttctactgca gattgtgttc ctgtgttgat atatgataag aaacatagtg
    14221 ccatagctgc cattcatgcc ggatggagag ggacggtagc atacatcgtg cgtgatactt
    14281 tgttgcggat ggaaaaggag tttggcacaa gtggagaaga tgtagttgcc tgtatcggtc
    14341 cgagtatctc attggcttct tttgaagtgg gtgaggaagt gtacgaagca tttcagaaga
    14401 atggttttga tatgcctcgt atttctatca ggaaagagga aaccggaaaa catcatatcg
    14461 acttgtggga agcgaaccgg atgcaaatcc ttgctttcgg tgtgccgtcc ggccaggtgg
    14521 agcttgcccg gatatgtacg tatattcatc acgacgagtt tttctcggca aggcgtttgg
    14581 gcattaagtc cggacggatt ctgtcgggga tcatgattca taaataatag acttgaacgt
    14641 aagttgatat aaacttgaat aaaagtatgt ttgaaataaa agtatctcag gaaataaaga
    14701 acgcctgccc tgtttttgcc ggagcagccg tatatgcagc agtgaagaat actgcttact
    14761 gcgatggact ttggaaagaa ataaatactt tcacagaaga cttgactacc accacccaaa
    14821 tggcagacat taagttgcaa cctgtgattg ctgctacccg tgaggcttat aagcgttgcg
    14881 gaaaagatcc ggggcgttat cgtccgtcgg cagaagcgct gcgccgtcgc ctgatgcgtg
    14941 gcatcccttt gtatcagatt gatactttgg ttgacct
//
