LOCUS       c00015_gnlPro..        13436 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AACLIHAB_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:57:16
            Original ID  :: gnl|Prokka|AACLIHAB_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13436
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13436
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3436](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3436
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13436
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13436
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..3436
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="PFOR_II (E-value: 4.9e-18, bitscore: 58.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 8.7e-71, bitscore: 231.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.6e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-11, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.5e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 14.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDEWAAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTY
                     TASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAE
                     GSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAE
                     FRARALNPMKPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLF
                     DYYGAEDAERVIIAMGSVTEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKT
                     AKSIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFE
                     NLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVK
                     IIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMY
                     DVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNR
                     TNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTV
                     DPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKR
                     GVAAFVPEWNAENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTF
                     RIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLV
                     DIKANVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVP
                     STPYTMNEKGHGPAWANSLFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYK
                     EVFAEWINNMLDAEKTKELAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDG
                     ASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKK
                     DLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGK
                     SQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQ
                     YPAEAEELFKAAEENAKWRYNSYKRLARENWGADTAE"
     CDS             3561..3749
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3760..4620)
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(4648..5478)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg15_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-28, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(5475..6701)
                     /locus_tag="ctg15_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7174..8460
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQPFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(8423..8755)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSAGRMVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(8783..11515)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63.6; E-value: 6.4e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_8"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.2e-19, bitscore:
                     63.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKIAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDQLIQLSHQLEEATHA
                     KLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLRLVNQILD
                     FRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDNMPDTDYHTLADMEKL
                     ERIYFNLLSNAFKFTPENGRIAVRLSSLSKEDKRWIRFTVANTGSMISAEHIRNVFDRF
                     YKIDMHHTGSGIGLALVKAFVEMHGGTISVESDEKQGTVFTVELPVQSCEAVAAEPDTT
                     LVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYMVIEAADG
                     SEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQG
                     YDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVERFK
                     SLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASS
                     DMTVAEIGYEVGFSSPSYFTKCYKEQFGESPTDFLKRKG"
     CDS             complement(11848..13074)
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="MLFFLIVPLFLSLFYKPIAYLCGRSLNNKLKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYDSDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLMVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 cgtagacgaa tgggctgccg caggacgtaa gaacatcttc ggcgaaacag tattggtaca
       61 ggaaatgcaa tctgaaggtg gtgctgccgg tgcagttcac ggttctcttc aggctggtgc
      121 attgactact acttacactg cttctcaggg tcttcttttg atgatcccta acatgtacaa
      181 gattgccggt gaattcttgc cttgtgtatt ccacgtttct gctcgtacac tggcttctca
      241 cgcattgtgt atcttcggtg accatcagga cgtaatgtca gctcgtcaaa ccggcttcgc
      301 tatgttggca gaaggttctg tacaggaagt tatggatttg gcaggtgttg ctcatctggc
      361 tactatcaaa tcacgcgttc cgttcatgaa cttcttcgat ggtttccgta cttctcacga
      421 aatccagaag atcgaaatgt tggaaaacga cgacctcgct ccgctgatcg accaggaagc
      481 tttggctgaa ttccgtgccc gtgcactgaa tccgatgaag ccggttgccc gtggtatggc
      541 tgaaaacccc gaccacttct tccaacatcg tgaatcatgc aataactact atgaagcagt
      601 tcctgctatc gtagaagaat acatgaacga aatttccaag atcacaggcc gcaaatacgg
      661 tttgttcgat tactacggtg cagaagatgc agaacgcgta attatcgcaa tgggttctgt
      721 aactgaagct gcccgcgaag ctatcgacca cttggtagca aacggcgaaa aagtaggtat
      781 ggttgccgta cacttgtatc gtccgttctc tgctaaacac ttcctggctg ctgtacccaa
      841 gactgcaaag agcatcgcag tgcttgaccg tacaaaagaa ccgggtgcta acggcgaacc
      901 tctttacctt gacgttaaag actgcttcta tggcgcagaa aatgctcctg ttatcgttgg
      961 cggtcgctac ggtctgggtt caaaagatac aactccggca cagatcatct ctgtattcga
     1021 aaacttggct atgccaatgc cgaagaacca cttcactatc ggtatcgtag acgacgttac
     1081 gttcacttct cttcctcaga aagaagaaat cgctctgggc ggtgaaggta tgttcgaagc
     1141 taaattctac ggtctgggtg ctgacggtac tgtaggtgcc aacaagaact ctgttaagat
     1201 tatcggtgac aacaccgaca aacactgtca ggcttacttc tcttacgact ccaagaagtc
     1261 gggtggtttc acttgttctc acttgcgttt cggtgatact ccgatccgtt ctacttactt
     1321 ggtaaatact ccgaacttcg ttgcttgtca cgttcaggct tacctgcaca tgtacgacgt
     1381 aacacgtggt ttgcgtaaga acggttcttt cttgctgaat accatctggg aaggcgaaga
     1441 actggctaag aacctgccta acaaggtgaa gaaatacttt gcacagaaca acatctctgt
     1501 atactatatc aacgcaactc agattgcaat ggaaattggt ttgggcaacc gtaccaatac
     1561 aatccttcag tctgcattct tccgtatcac aggcgtaatc cctgtagatc aagctgttga
     1621 acagatgaag aaattcatcg ttaagtctta cggcaagaag ggtgaagacg ttgttaacaa
     1681 gaactacgct gctgtagacc gcggtggtga atacaagact ctgactgtcg atcctgcttg
     1741 ggctaacctg ccggatgatg caaaagcaga aaacaatgat cctgctttca tcaacgaagt
     1801 agttcgtccg atcaatgcac aggacggtga cttgctgccg gtatctgcat tcaagggtat
     1861 cgaagacggt acttggtatc aaggtacttc caaatacgaa aaacgtggtg tagctgcatt
     1921 cgttcccgaa tggaatgctg aaaactgtat tcagtgtaac aagtgtgctt acgtttgtcc
     1981 tcacgcttct atccgtccgt tcgtactcga tgctgaagag cagaagggtg ctaagttcga
     2041 gcaactgaaa gctgtaggta aagcattcga tggtatgaca ttccgtattc aggtagacgt
     2101 tctcgattgt ctgggttgcg gtaactgtgc cgacatctgt ccgggtaatc cgaagaaggg
     2161 tggcaaggca ttgaccatga aacaccttga aagccagttg gccgaagctg ataactggac
     2221 ttactgcgct gaaaacgtga agagcaaaca acacctggta gacatcaagg ctaacgtgaa
     2281 gaactctcag ttcgcaactc cgttgtttga gttctcaggc gcttgctccg gttgtggtga
     2341 aactccgtac gtgaaactga tttctcagtt gttcggtgac cgtgaaatgg ttgctaacgc
     2401 tacaggatgt tcttctatct actccggttc agttccttct actccgtaca ctatgaacga
     2461 aaagggtcac ggtcctgcat gggctaactc cttgttcgaa gacttctgtg aatttggtct
     2521 gggtatggaa ctggctaacg aaaagatgcg tgcccgtctg gtgaaagtaa tgaacgaagc
     2581 tatcgcttct gattgctgcc cggctgaata caaagaagta tttgctgaat ggatcaacaa
     2641 tatgctggat gcagaaaaga ctaaggaact ggccgaaaag atcattccga tggtagaagc
     2701 tgctaaagat aaatgcaacc actgcaagca aatcgctgat ctgcaacaat atcttgttaa
     2761 acgcagccaa tggatcatcg gtggtgacgg tgcttcttat gatatcggtt acggtggtct
     2821 tgaccatgta atcgcttccg gtaaggacgt taacatcctt gtattggata ctgaggttta
     2881 ctctaacaca ggtggtcagt cttctaaagc tactccggta ggcgctatcg ctaagtttgc
     2941 tgctgcaggt aagcgtgtac gtaagaaaga cctcggtctg atggctacta cttacggtta
     3001 tgtatatgtt gctcagattg ctatgggtgc tgaccaggct cagactctga aagctatccg
     3061 tgaagctgaa gcatatccgg gaccatcact gatcatcgct tacgctccat gtatcaacca
     3121 cggtctgaaa gccggtatgg gtaagagcca ggaagaagaa gaaaaggctg ttaagtgcgg
     3181 ttactggcac ttgtggcgtt acaaccctgc tttggaagaa gaaggcaaga atccgttcca
     3241 actggatagc aaagaaccta actgggaaga cttccaaggt ttcttgaagg gtgaagttcg
     3301 ttacgcttct gtaatgaaac aatatcctgc tgaagctgaa gaactgttta aagctgctga
     3361 agaaaacgct aaatggcgtt acaacagcta caaacgtctt gccagagaaa actggggagc
     3421 tgatacagct gaataataag tagaaatact ttgtacataa taaaaggcag gaatcctgga
     3481 aacagattcc tgcctttttt gtttatatct tagaagtaac gattacttct cacgaagata
     3541 ttcattaaaa ctctaaagat atgatcggat ttgttatttg gattatcggt ttgatactga
     3601 ctttcagagc tgccatagag atttggaata taaatgcggc tgtagagaaa agacttatag
     3661 cgattgtatt aatcgttctt accagctggc tgggactact tttctactac ttctatggta
     3721 aagaaagaat ggcgggatgg ttgaagtagt gtttgcatat caatctttct caggaatcca
     3781 actgttcacc agttcctgat gttcttccat ccattgacgg gcagcctgtc tttccgttgt
     3841 ctgcgcctct tccagagcag tcattaagga gctgatttcc gcatctgtca gacgaatgtt
     3901 gcccaaaagt tcggcagcaa aagggtcttt ctcgctaaaa cctttccatg ctatggtatg
     3961 aatggattcc gtatttccat atatcagctt cgggtcctga agaactttca gcttgaaacg
     4021 gtcgaacatc cagtgaggcg tccatcccgt cacgacaatc cagtctttct tatcaatcgc
     4081 tttctttagg gaagcagtca tggcaggtcc gctcgaagtc atcagtttat aatccaatcc
     4141 atagtctttg atggcctgat cggtagcttt cataataccg gctccggcat caataccgac
     4201 aatctgaccg gagaaacgtt ccttttccgc gttcagttct tcgattgagt tgatcgtaac
     4261 gtaatccgga accaccagcc cgatacgggc accatcataa atatccccga taacttcgag
     4321 tttatccccg tattgtttca tataatcttc catagtgaca ggcatccaga catccataaa
     4381 tacgtctgct ttcttacggg agatagaggt aaatataggt gcaaggtcgg cattcagcaa
     4441 ctttacatcg tacccctgat cttcaaaaat cgctttggca aggtttgtca ttgcaatacc
     4501 ttccgaccag ttggcataag cgatacttat cttcttactc tttccgttgt ctccgcagga
     4561 aacgaaggtt aagagtatgc cggcaataaa cattgccgca atcattttta tcttattcat
     4621 tgattattcc tttctttggt gtgattctta tttcttttta ctttttctgt tatctgccat
     4681 accctgagtg atgcggtcca gcacgatcgc caatatcacg actgcgatac cgccttcaaa
     4741 tccgagtccg attttcattt gggtgatacc tttcagcacg atttctccca atcctccggc
     4801 agaaatcatg gcagcaatca ctaccatcga aagtgacatc atgatcgtct ggttgattcc
     4861 cgtcagaata gtaggcaacg ccaaaggcaa ttgcacctta taaagaagct gccagggagt
     4921 agctccaaaa gagcgggagg cttctactac gtttttagga acctgacgaa tgcccagacc
     4981 ggtcagacga accacaggag gcattgcaaa gatgatggtg gcaaaagctc ccggcacagt
     5041 tcccaatccg aagaatagaa cggcaggaat cagatagaca aaggcaggca ttgtctgcat
     5101 aaagtcgagg acagggcgca ttatcttgtt acaacgatca ctgttggcag tccagattcc
     5161 caacggaacg cctaaaagca atgccagaca agtggaagaa agtaccaatg ccaatgtctg
     5221 catcgtttct tcccaaaagc ccatgccgta aataagcaat aaacccaaga gggtaaatac
     5281 ggctgtcccc ttacccgact taaaccaggc gagcgcagcc agcactgcaa ttgtgatata
     5341 aaaaggtatt ccaaacagta cgtgctggaa tccgtctatg aatcctccga tccccatgct
     5401 gagagcatca aaaaaggaag caaaatgttc tgtgagccaa ttaatggcag tctctatata
     5461 ttgtccgata tttatcataa ttctattgcg ttttgaatga tttcattaat ttcttcttta
     5521 tcttttcccg ttacttcgat aatcaatgag gaaagtggca ctacgccttc aaactcccga
     5581 ttctcattta cgacccagat tggcgagttc gtttttgtca tcaacggaag aatatcttcc
     5641 agcaccgtat cccccagtac cgaatgaact tcatgtctta ctacggactc gatggagcgg
     5701 atttgctctt ttcgcagttt cagcaagtca ttcaaccgca cctctcctac taacagatta
     5761 ttggaatcga ctaccggaag aacggtcaga ttccgttcgc gcatcttacg gatcagcacc
     5821 tccgggcctt ctttcttcaa acgtgccact atgggtttat ctaccataac ggaagaagct
     5881 gtaattatct tgcttcgatc tacattctcc acaaatcgtt ctacataagc gttggcaggt
     5941 tcggtcagga tttcttccga tgtaccgatt tgtacaattt ctccatcctt catgatagca
     6001 atccggtcac ccaatttaat cgcttcactc aggtcgtgag taataaagac aatcgttttt
     6061 ttcatcttcg actgcaaagt cagcagttca tcctgcatct gtacgcgaat caaaggatcg
     6121 agtgccgaga aggcctcatc catcaacagg acttcgggat tattggccaa agcccgcgcc
     6181 agcccgacac gctgctgcat cccacccgac aattcactga ccatctgatt ctcgtagcct
     6241 ttcagcccca ccagttgcat actttccatc gctttctgct cccgttctcc ctttttaact
     6301 ccctgtagtt cgagtccgaa agctatatta tgcaagacag atcggtgagg aagcagaccg
     6361 aagttctgaa agaccatagc cagttctttc cggcgaatct gcaacagttc tttgtccgac
     6421 actttggcta tgtctgttcc attgataatc acttctccgg aagtagggcg tatcaaacgg
     6481 ttgatgcagc ggagtaaagt ggactttcca ctaccggaca gccccataat gacgaatatt
     6541 tcgccttcat taatggaaag attcgcatct ttcaccgcaa ccgtacatcc ggtcgctttc
     6601 aatatttcac tttttgtttt accttctttc aacatcttca aagccttctg cttctcattg
     6661 ccaaaaacca gatagagatc tttaatttct attttactca tacaataaaa tggtttaggt
     6721 tattaaaata atatacacag caagacaaga acaaacgata acaggaatct ttctttatat
     6781 cgtataaagt tctgatttaa atacgggaca aataacaatg aatcccgaaa taattaataa
     6841 aatgattatt gacagactga gtaattaaaa aaggaataga atttgataag ataatccttt
     6901 caacgaatag caaaaaatag catttttatg tataaaaaca gcctgtttca gtatcttgct
     6961 ggcacaaaga tacaaaaaac agattaaaca tgcaaattat attcaaaatc cggggcatac
     7021 agagggcttt atttgtaatg atatggaaag ttttcgggta atattcccct atcactcagc
     7081 aaaatagaac aaaccggcag ataaatataa aataagtttg aatatttcac ctaaacaccg
     7141 tatatttggc gtcaataact aaactagatt tatatgttca acagggctat tacaattttc
     7201 ctggggaagg ataattgtca ttacacaaca aaagaaaaac aaacaggtac tgccacacta
     7261 gacgacaaaa gccaagtaca gttccttagt aaaaagaacc ccaaaatgcc gtttttctat
     7321 agtcggcgga atctctacat gataggtttc ctgctcgctt ttatagtgac tctgctcgaa
     7381 tttatgcgag gacggcatca aaactttatg gtcttctcag acgctactca attcttctgg
     7441 caaggcatca gcccatacac aaccgaattt gtagaagctc acggacgcta cttcctttat
     7501 tctcctgttt tcacggtatt gttcgctccg tttgcgtatc tgcctgcatg gctgggacct
     7561 ttcgcgtgga atctattcaa ttattcattg ttctttgtag cgatcttcac gctgccccaa
     7621 ccattcaccc agcaacagaa atgccgtatg ttcctttttc tgttactgat tttaggacaa
     7681 agtttacttt catttcagta taacataacg gtagcctatt tattcttatt cgcctatacg
     7741 ttattggaaa aagaccgggg atttctagct gttctgttaa tcatgatttc gggatgtacc
     7801 aaagtatacg gaattttcga actggcattg ttgctgtgct atcctcacgt atggcgtaac
     7861 tttggctatg ccgttgcaat gggcatcgta ttgcttgcgt taccgttaat caaaatagct
     7921 cctgcagatt tgctccccta ttatgaagaa tggtgccata gtcttgctgt tcatcaatcc
     7981 accggagctt atgattcatt tttctatgcc cgccccattg cagcatggac attgccacat
     8041 ttccgtgcac ttcagatagg aatgctcggt ctgctgactc tgctcttttt ggggaatttc
     8101 cgcaaatggt cgtcttttgc cttccgtgcc caggctttgg gtatcttaat gggatgggtg
     8161 gtattattga gtgactctgc cgaaaagcat acctatatca tagcattggc aggtttcatg
     8221 ctctggtatt ggagcaggcc aacacgtacc gcaacagaca agattctatt ttggtgctgt
     8281 tttgtgctgt tatgtatcgt tcctatcgac atatttgtcc ctgttcccat cagagatttc
     8341 atcaccagga ccttatggct tcatgtatgg gttttcttta ttgtatggat acggatgata
     8401 tggcttacct tccttgcatc cttcattcat ccacgtgcca caaatgttct ttcagattaa
     8461 cgcatccgtt agctttgaaa gaaacttctt ctgccagcaa gagttgtttt tgttccaccc
     8521 aaccgggcac catccttccg gcggaattta caactctatg gcagggaatg gataattcat
     8581 ccggcacttc tttcaaagca cgccccacca tccgcgagca ttggggtgcc cccaagagca
     8641 aagcaatacc tccataggta gatacttttc ctacaggtat ctgggatacg acttcgtaca
     8701 cttccttccg aaaggattcg gaaaagctct ctttatctac tttataatct ttcatatatc
     8761 cctctttacg atctcaatga aatcatcctt tccttttcag gaagtctgtc gggctctctc
     8821 cgaactgctc tttatagcac ttggtgaaat aagaaggtga actgaaaccg acttcataac
     8881 caatctccgc tacggtcatg tccgaagaag caagcaaaga agctgccttc ttcaaacggg
     8941 cgatacggag caattcattc ggagagtagt tagtcaacga tttaatcttg cggtaaagct
     9001 gcacacggct tagtcccata tctttgccca agtcctccac attcaaaccg gagtctccca
     9061 ttttctcttc aatcaatgac ttgaatcttt ctacaaaatc cttgtccata tcgcagacat
     9121 cttccttcgc caatgtctgc ccgtcaccaa agaactgttt cagacgacgg tgagaatcaa
     9181 tcaggttgcg gacacgtgcc agcaacagtt gtgaactgaa cggctttgaa atataagaat
     9241 ccgcaccacc gtcatatccc tgaatacgct gttcgtccag tgaacacgct gtcagcagaa
     9301 taaccggaat atgacaggtc tgtaactcac ttttcagccg gcggcaacat tcaatgccat
     9361 caatgcccgg catcatcaca tcggaaatga tcaggtccgg aacatacttc atagccttac
     9421 ggattccttc ggagccgtct gccgcttcaa tcaccatata atctgtatgc aacagcgtat
     9481 ggacatacga acggatatcc tcattatcat caataatcag tacggacgat ttggaagagt
     9541 catatccttt ttccagttct tcctcttccg ccaatagaac atctgttgta cgggaatccg
     9601 cagaaacaag ggtggtatcc ggttcggcag caacagcctc gcaagactgt acaggcagtt
     9661 caacggtaaa gaccgtaccc tgtttctcat cgctctctac agagatcgta ccaccgtgca
     9721 tttctacgaa ggcttttacc aatgccagtc cgattcccga accggtatgg tgcatatcga
     9781 ttttatagaa acggtcgaat acattgcgga tatgttcggc agaaatcata gaaccggtat
     9841 ttgccaccgt gaaacgtatc catcgtttgt cctctttact aagggaagac agacgaacgg
     9901 caattcttcc gttttccggt gtaaacttaa aggcattgga cagtagattg aaataaatgc
     9961 gttccagctt ctccatgtct gccagtgtat gataatccgt atccggcata ttatcaaaag
    10021 aaaaatggat atgtttctta cgggctgccg cctgaaaaga ctcattccat ccttcgaaag
    10081 aagaaaggac atccaccgta accggagtat attccatctt gccattttca tatttacgga
    10141 aatccagaat ctgattgacc agacgcagaa gaatgttcac attccgctga atcagcatga
    10201 gcatccggtg ctgatctccg ctcagtgtct tgtccgccaa caaatgttct accggatcgg
    10261 caactaatgt caacggagta cggaagtcgt gagaaatatt ggtgaagaat accagcttgg
    10321 catgggtagc ttcttctagt tgatgagaaa gttgtatcaa ttggtcacgc tgttcttcca
    10381 attgctgttt ctgtttaaaa agctctttat tcaagcgatt cttagagcgg agtgatttat
    10441 aaacgaccaa taataagccg gctaccaata aaaggataat cagactgccg tataaaacga
    10501 cctgttgtgt agctacctga gaaaggtatc caccgatacg tccgttgagc gtttcaatct
    10561 ttttgtcgag ttcggaaatg tgtgtggtct gcaattgcat gacgtgcgcg ttggtacggt
    10621 cgacaacagc ggtattcatc accgtttctt tgggataggg tttcttctcc agaatatcca
    10681 tagccagttg cagtacctta tcgccattgg tcggatagat aaaggtagca tccagcacac
    10741 tgtccagaac cagttccagc ccgtttccct tacccggcaa ggcatctatg ccgacaaaaa
    10801 tcatttcctt ctcccgccct gctatctttg ctgcctgata ggcacccgga gcgatacggt
    10861 cattatgagc atacacagca tcaatcttag gatgcctccg aagcatacta tccatttcta
    10921 tctctgccgg accacgttcc caagcagcat ccgctttatc aatcagcttt atatccggga
    10981 atttactgat ggcagccata aatccctgat gccgttccat tgcaggagtc gaaccgctca
    11041 atcctgtcag ttctactata tttcccttcc ctttcagact ggaggcaata tagtttccta
    11101 ccgaacgacc gatttcataa ttatcggctc cgatataggc agtatattta tccgaaagaa
    11161 tcttccggtc tacaagaata acggggatgc ctttctgata agcttcttct acaatcggag
    11221 tcataggagc agcttcgtta gcggaaataa tcagcagatc gactccttcg tccataaaat
    11281 aatggacatc ttccgcctgc ttactgttat catcccctgc cgaacggatt tccaccgaaa
    11341 caccattata aaacatcgct tcccgaagaa tctcatcatt catcttatgt cgccatgaat
    11401 catcgctgca ttgggccacc ccaatacgaa aacggggtgt atcctgccgg caagccgtca
    11461 tcccgattaa acaaaacagc accagcatcc acttcagata tctcatcgtc ttcatccatc
    11521 tcatcatttc gtagttcttt ctgtaatcca attaagaaca aaaataagaa ataatactgt
    11581 aaagttctct aacttcagct atttattatt ctaaaaagaa ggaaagcagt cctctttcag
    11641 actatcggaa agtattaaca aaagtataaa gcgtaaaaca aacacttaat caatgttata
    11701 aaacatagcg ttttacttgg ataatttgca gatttcacag aagtccgtat ctttgcattg
    11761 tgtttttcat agtattagat ttaaggttaa caaaggttgg agcaaggcgt tgctcctttt
    11821 tttatgccct gacctttcat ctaccggtta gttttcatcc cattcctttt ccagtttacc
    11881 atcaatagtg tagcgtttcc atcgtcccac acggcgacca ttcttatatt ccccacattc
    11941 acgaagctgg tcattcttta cataacgagc ttcgaacggt ccgttctgcc gtccgttcac
    12001 ataggtagaa gtttcccaat aatcaaagcg gttgctcacc atcagccgtc gttccttgcc
    12061 atgcaatctg ccggcctgat aggtagcttc atatctcaat tcaccatttt ccagattata
    12121 ttcacggtat aaaccgtctt tacggtcgtt cttcatataa tattctttct gccttacccc
    12181 acttccgttg gcaaatgaga catggagtcc atcttctttt ccatccagat aggtttcaat
    12241 catcagtgta tcgccgcttt cggcaaaagt agtccaccga ccattcttct ttccattctt
    12301 ataactaccc agtatacgtg gcgagccaaa cgtaaacacg gacgaatatt caccgtcctg
    12361 caaaccttct tcattgaaat aaacggtctc atacaaatca taagtacctt tcagaaaagt
    12421 atattgtttg cctacctgct tcccgtcctt gtaattatgc tctttccgca aagtaccgtc
    12481 agaatcgtat gagagctgtt tcccgtgctc tttccccatc cggaagtttc tttcactttc
    12541 cacttttccg gtagtaaagt aacttttgct cgtaccgtcc agcttacctt ccttatagga
    12601 tttttcttct tttagcttac cgtcaaactt ggagttaatc ttgaagagac catccttccg
    12661 tccttcttta taacttcctt ccgttattaa tatattgtct acatattctt tgtatccgcc
    12721 atcatagaaa ccatccttaa aagatgccag cacataggcg gaatgataac catctatgat
    12781 gcgatgttcg ccattcaatg ctttttccgt tttcagttcc tgaaacaaca gtctgccatc
    12841 gcctacattg acaacggata cctgatcgat cttatattcc ttttgcgcaa acaaaggaag
    12901 agcaagatat aaaaacaaaa atacgttcca gctttttgat ctgaggaagt ttgaaatgtg
    12961 tttcataaag tagttttctc tttttaattt attatttaaa gacctgccgc aaagataggc
    13021 aatcggctta taaaacaagg aaagaaagag ggggacaatt agaaaaaaga gcatctgtta
    13081 ttatcactct aataattaac agattaatta ttaaatcaaa acacagggaa gggggacatt
    13141 tactgaaata agaaacagaa aaccggagat ataccctgaa ttgcagggta tatctccggt
    13201 ttttgtattt aaagagattc tacaacaatc tgtctttcag aacaaccgga agttcgggca
    13261 ttgcaccgct ctgcgtacaa acataagcgg aaacttcgac agccagctta tgagcttcgg
    13321 gaacggactt gccattcaga atggaagcac agaaagcggc agtaaaggaa tcccccgctc
    13381 ctaccgtatc ggctaccgga accttcggcg tttcctgaaa agaaacgact cccgga
//
