LOCUS       gnlProkkaFDKMJMEP_71   11491 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDKMJMEP_71.
ACCESSION   gnlProkkaFDKMJMEP_71
VERSION     gnlProkkaFDKMJMEP_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:41:59
            Original ID  :: gnl|Prokka|FDKMJMEP_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11491
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..951
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.5;
                     E-value: 6.1e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDVSRRIKNP
                     RSTADNDTIGQMYTFSLKDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQNVVIDGEILF
                     GGNYAMTNREERLSDLVNKAGGPTSLAYLRGAKLTRVASAGEKKRMGDVIRLMSRQLGE
                     AMIDSLGIGVEDTFTVGIDLEKALTNPKGSADLVLREGDVVFIPKNTNTVTINGAVMVP
                     NTVSYMKGKDVDYYLNQAGGYSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVP
                     GKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..11491
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2177:6491]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2178..6491
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11491
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11491
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             966..2114
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             2178..2897
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2918..4219
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="CTP_transf_like (E-value: 5.6e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 5.8e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 6.6e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             4236..5360
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.1e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5370..6491
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg71_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_6"
                     /sec_met_domain="Aminotran_5 (E-value: 4.4e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5460..6467
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg71_6_Aminotran_5.1"
                     /locus_tag="ctg71_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6488..6631
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6834..8318
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_8"
                     /sec_met_domain="Polysacc_synt (E-value: 3.9e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8272..9531
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9540..10289
                     /locus_tag="ctg71_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             10289..11329
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ggtgaagtcg cgcaccccga ttcctatccc tatgctgata acatgacact tgaggatctg
       61 atcatccagg ccggtggctt gaaagaagcc gcctctactg tccgcattga tgtgtcgaga
      121 cgaatcaaga atccccgtag taccgcggat aatgatacta tcggtcagat gtataccttc
      181 tctttaaagg atggttttgt catcgacggt cagcccggtt ttatccttca gccttatgac
      241 gaagtttatg tccgtcgcag tcccggttat caggcgcaac agaatgtagt cattgatggt
      301 gaaatattgt ttggaggaaa ttatgccatg accaaccgtg aggaacgtct ttccgatctg
      361 gtgaataaag cgggtggtcc taccagtctt gcctatctcc gtggtgcgaa attgacccgt
      421 gtggcaagtg ccggtgagaa gaaacgtatg ggtgatgtga ttcgcctgat gagcaggcaa
      481 ttgggtgaag ccatgattga ctctttgggt attggtgttg aggatacctt tacggtaggc
      541 attgatctgg agaaggcttt gactaatcct aagggtagtg ccgaccttgt cctacgtgaa
      601 ggtgatgtgg tctttatacc taagaatact aatactgtaa ctatcaatgg tgctgttatg
      661 gtccccaata cggtttctta tatgaaggga aaggatgtgg attattacct gaatcaggcc
      721 ggtggctatt ctgataatgc aaggaagagt aagaagttca ttgtttacat gaatggtcag
      781 gtgacgaagg ttaagggtag tggtaagaaa cagattgagc cggggtgtga gattattgtg
      841 cctggtaagg ctaagaagaa agggaacata gctaatattt taggttatgc tacttccttc
      901 agttctttgg gtatgatgat tgcttctatt gctaatctta taaagaaata atagaattta
      961 cttttatgtc agaacaacga caggataaaa acttgctctc tgaaccacac aagacagaaa
     1021 gtgatgagat agaaattgat ttggtcgata tctttcgcaa gattattgct attcgtaaaa
     1081 aattatacaa agccgttgga attggtttta ttattggaat aattgtagcg gtaagtatcc
     1141 ctaaacagta tacagtaaag gttacccttt ctcctgaaat gggtaatgcg aaggggagta
     1201 atggtttagc cggacttgct gcctcgtttt taggagatgg ggctctaata ggggaaagca
     1261 cagatgcctt gaacgcttct ctttcagcag atattgtttc ttcaactcct tttttattgg
     1321 aacttttaga aatggaagtc tccgtttcta aaaaggatga taaaatgact ttggggtctt
     1381 atctcgatga agagtcatct ccttggtggg attatcttat aggttttccg ggcatagtaa
     1441 taggaggagt taaatcatta ttcggagaag atacggttcc tgccagtgga gggcggcaag
     1501 gaactatcga attgacgaaa gaagtaaatg agaagattaa ttttcttaaa aagaagatta
     1561 gtgcatccat tgataagaaa accgccataa cgagcattac ggtcacctta caaaatccgc
     1621 agatcactgc ggttatagca gattctgtcg ttcataaatt acaggaatat attattgggt
     1681 atcgaacttc aaaagtaaaa gaagactgtg cgtatttgga acggttgttt aaagaacgtc
     1741 agcaggaata ttatgctgct caaagaaaat atgcggatta tgtagacgcc catgataatg
     1801 tggttcttca aagtgtacgt gctgagcagg agcgtttaca gaacgacatg agtttggctt
     1861 atcagatata tagtcaggtt gctaatcagt tgcaggtatc cagagccaaa gtacaggagg
     1921 aaaagccagt ctttgcagta gttgagcctg ccgttgtacc tttgaaacct tcaggtatgg
     1981 gactcaaaat ttatatttta ttatttgtgt tcctgtccgt atctggtact ctcgtgtggg
     2041 tgttttttgg caaaagtctg ctggctagct tgagaaaaga actgaaaaat aaggagatag
     2101 aacaggataa atgatgctaa aacgtcgttt acaacattct tacatcaatt aaattcactt
     2161 actatattat taaacgaatg atacgtacag ctatgataat ggctgcgggc atgggaaccc
     2221 gttttggcca atatacagaa ttgataccta aagggttcgt caaagtggga ggtattccaa
     2281 tgatagttcg ttctattgat actttgttat catgtggcat tgagcgaatt gtaatcggta
     2341 caggatataa acaagaagtt tatgaagaat tgaagacaga ctatcctatg cttgaaacct
     2401 gttttagtcc tcgttatgct gaaacaaata gtatgtatac tttatataat acgcgggaga
     2461 ttctgggcaa tgatgatttt ttattgttag agtcagattt gatttttgag aaacaagcaa
     2521 taatgagctt attggagtgt cctgcggcag atgcaatgct aatagctcca gtgacaaagt
     2581 ttcaagatca gtattatgtg gaacatgatg ataattttcg cctttcttca tgttctgtca
     2641 ataagaataa actaaacgct aaaggcgaat tggtcggcat ccataaacta tccggttcct
     2701 tttacaaaat aatgtgtgct gattatgcga gtattgttga tgaacaaccc aatttgggat
     2761 atgagtatga attactacga atatcttgtt ctcaatctcc tgtttatgtg cataaagtag
     2821 aagggctgaa atggtatgaa atcgatgaca tatcagattt ggaatatgca gagaaatata
     2881 ttgttccgta ttgttaatta aaataatata tcaaattatg agtaagacag tttatattgg
     2941 gatgactgcg gatattatgc atccaggact tatccgcatt attaatgagg ctactaaata
     3001 cggtgatgtt ataattggtc ttcttacaga taaagctatt gcggagcata aacgccttcc
     3061 ttatctgacc tatgaacaac gaaaagaggt agttcagaat attaaaggcg tatgtaaagt
     3121 tgttcctcaa gaagaatgga gctatgttga gaatctcaaa cgcattaaac ctgactatat
     3181 aattcatggt gacgactgga aaaccgggcc tttacgtgaa gaacgtgtgc gcgtatttga
     3241 agtgatgaat gaacagggag gaaaggttat cgaaattcca tatactttgg gaattaattc
     3301 atcttctttg gataaagata ttaaggctat aggtacaacc cctgatgtac gtttaaaatc
     3361 acttcgtcgt ttgataaatg ccaaacccgt agttcgtatt ttggaagctc atgatggact
     3421 atgtggcttg ataattgaaa atcaggaaat attaaaaggg gataagaggg aagtatttga
     3481 cggaatgtgg tctagtagcc ttacggattc aaccagtaaa ggtaaacctg atattgaggc
     3541 ggttgattta actacccgat tgcaagattt gaataatatt ctggagtgta ctactaaacc
     3601 tattattttt gatggagata caggtggtaa aattgaacat ttcgtattta cagtacgcac
     3661 tttagaacgt catggaattt cagctataat aattgaagat aaagttggat taaaaaagaa
     3721 ttcattgttt ggtacagatg ttattcaaac tcaagataca atcgaaggtt tctgtaataa
     3781 gatcaaagca ggaaaggcat ctcagattac tgatgatttt atgattatcg ctcgtattga
     3841 gagccttata gcgggaaagc cggtaagtga tgctttagag agagcttttg catatgtcca
     3901 agcgggagcg gacggtatta tgatacatag caaaaataag tcgggtgaag atataaaaga
     3961 attttgtttg gcgtttcgaa aacagtatgc tcatgtacct atcgtggttg tgcctactac
     4021 atatgatcat atttatgagt ctgaattgtg tgattggggt gtgaatataa ttatttatgc
     4081 taatcatatg cttcgtgccg cttatcctgc tatgatgaat gtcgcaaaga taatattaga
     4141 gaatgaacgt gctttagagg tgcgcgaact gtgtatgccc ataaaagaaa tattggaact
     4201 gattccaggt actaaataaa aagaggaata tcattatgtt aagcgtagaa aaagtttatg
     4261 aaacgtttct gagtcatgac gttgattttt ttacaggagt tccagactca ttactaaaaa
     4321 atatttgtgc ctatatcaca gaccatactt cacgtgagaa acatatcata gctgctaatg
     4381 aaggtgcggc tgtaggaatt gcttcaggtt attatatggc atcaggtaag gttcctgtgg
     4441 tttatatgca aaattccggc ttgggtaata ctgttaatcc tctgctgtct cttgcagatg
     4501 aacaagtata cagttttcca atgcttttga tgattggctg gcgtggtgaa ccgggaacaa
     4561 aagatgaacc tcagcataaa aaacagggtg aggtaacttt agatttgttg aaagcaatgc
     4621 ggattcctta tataattctt gattcaaatg agaatgatgc atttattcag ctccatgata
     4681 tcatacaatc agcaaaaact aagaatattc ctcatgcaat aattattcgg aaagatgttt
     4741 ttggcaaata taaacttcaa aaagagttcg gatgtaatta tcctttatct cgtgaggatg
     4801 ctttgcaaat agttgtggat tatctgcctg aaaattcagt ggtcgtttct actactggca
     4861 agctttctcg tgagttattt gaatatcgag aaatgaaaga gcaaggtcat gaacatgatt
     4921 ttctcacggt aggctctatg ggacatagtt catcaatctc tttgggtatt gctatagcaa
     4981 agcaagatag acctgtttat tgcttggatg gtgatggagc atttattatg catttagggg
     5041 caattagtaa cattggcgat ttatctccta aaaactatta tcatattttg tttaacaatg
     5101 gtgctcacga gtctgtagga ggacagccta ctttaggatt tagtttagat attccggcta
     5161 ttgtccgggg gagcggatat aagcatactt atactgtttg tacaaaagtt gaaattgaag
     5221 aagcaatgaa gcagcttcca aagttatgtg gtcctgtttt gttggaaata aaggttaaaa
     5281 tagattctcg ggagaatttg ggacgtccca cgactactcc tatagagaat aaggagcatt
     5341 ttatggattt tttaaaataa atatattcga tgaaaataga aagaaaaata ttattaaatc
     5401 ctgggcctgc cactactact gacagtgtaa aaatggcaca agttgttccg gatatttgtc
     5461 ctcgcgagaa agaattcgca ggtatgatga aacaacttcg ggacgatttg gtcagagttg
     5521 ctcatgggaa tttggaaaaa cataccgctg tattattttg tggctcagga accatcaata
     5581 ttgatatatg tctaaattct cttcttcctg aagacaaaag ggtgcttata gtgaataatg
     5641 gggcatatag tacccgtgct gtagaagtgt gtcaatatta tggtttgcct catattaatt
     5701 tggaattttc cgtttacgaa cgtcctgatt tatcggtggt ggaaaatgtg ttgcaagaaa
     5761 atcctgatat agctatggtt tatactactc atcacgagac gggtacagga attctgaacc
     5821 ctattcgcga gatgggcgct atagctcata aatatcaggc taaatttgtc gtcgatacta
     5881 cttcttcttt gggcatgatt ccttttgata tagagaaaga taatgtggat ttttgtatgg
     5941 catctgctca aaaaggactt caagcgatga caggtctttc ttttattata ggcaatgagg
     6001 aacagattaa gttttcaaaa aaatatccca agcgttctta ctattgtaat ctttatttgc
     6061 agtatgagaa ttttgagaga acaggtgaaa tgcattttac tccaccggta caaactattt
     6121 acgccactcg tcaggcatta aatgaatatt ttgaagtggg tgaagaagct aagtttgccc
     6181 gtcacaaaag agtttttgag gctattcatt caggtataaa tgaaattggt cttaaaagtg
     6241 taataaagcg tgaatggcag tcaggactgg ttgtctcagt tcaataccca gaagatccca
     6301 actgggattt tgagaaaata catgattatt gttatgagcg tggatttacg atttatccag
     6361 gtaagatatc aactgaggat acttttagaa tctgtgcttt aggagagata gaagtagatg
     6421 atattgagaa cttctttaaa gtactaaaag ctgcattaaa tcattataac gtcacattac
     6481 cgatgtcatg attgcagaaa tattattgaa gattcgtcat ttttattttt cccttcgtgg
     6541 tatacacttc catccggaaa gtgttatttc tggagtgcct attcgtagct ttcgcttagt
     6601 aggcaaatat ggcaatatta atttgaggtg atgcattagg agttctttat tcttataaaa
     6661 aggcatcggt agttatagga gataatgttt gtgtagggta atttgctttt agtgggagag
     6721 accatattag aattgcggta aggggcgaag aagataataa ccaattagtg agaatattgg
     6781 aaaaatataa ttgatatcgg taaatgtagt tgtttttata ctgtatttaa gtaatggaaa
     6841 atctaaagca gaaaactgta tcaggaataa tgtggagcgc tatagaacgt ttctctttac
     6901 aaggagtaca gtttataatt caaataatat tagctcgttt gttactacca tcggattatg
     6961 gtatgatcgg gatgttagct atttttcttc aagtcgctca agtatttata gatagcggtt
     7021 ttacaaatgc tttaatccag aaaaaagata gaactgaaga ggattttgcc actgtctttt
     7081 attttaatat tcttgtcgca gtattattct atggtatatt gtttttttcg gcttctttga
     7141 ttgcagactt ttataatatg ccgactttag ttcttgtaat tcgttttata gcattgtcgt
     7201 tgataataaa tgctttatcg gctattcaca gaacgaaatt aattatttct gtaaacttta
     7261 aaactcaatc taaaatttca ttaggtgcag cttttatatc aggcgtgatt ggaatatgga
     7321 tggcttatgt cggttgcggg gtttgggctt tagtttggca aactctctta aatagtataa
     7381 ttttgacaat tttgttttac tgtttagttc attggaaacc tttacatact ttctccaaaa
     7441 gttcttttga aagattattc aatttcggat ctaaattatt gatctcaagt cttatcaata
     7501 cagtatatcg taatctgtat accattgtaa taggaaaaaa gttttctgtt gtagagcttg
     7561 gttactatac aagagcagaa caatttgcta tttttccttc caataattta aatgctttag
     7621 tttctagagt agcgtatcct attttaagtt ccattcaaga tgatgataaa tgtttaacaa
     7681 acgcatatcg aaattatatc agattatcct catatataat ttttccttta atggtaggtt
     7741 tacttgtttt ggctaatcct attattagtc tattgttaac agataaatgg tctggggttg
     7801 ttattctttt acagatatta tgtttggatt ggatgtttga tcatttgagc caaattaatt
     7861 tgaatttatt atgggttaaa ggaagatctg atctgtcgtt acgtcttgaa ataataaaaa
     7921 agacgattgc tatattcatt ctttttgtgt caattccatt tgggcttgag gtgatgtgtt
     7981 ggggtagagt tatttactct ctgatagcga catatttgaa tacatattat actaattctc
     8041 ttattgattt gaccttaaag ttgcaagtta aagatgtatt tccaagttta atactctctt
     8101 tcataatggg ggggatcgtt tttatatgta tttctttctt tgaaactgat atagtaaaaa
     8161 ttgtgattgg atgtattact gggatgtcct tctatatttt actttctttt ctttttaagc
     8221 tagattcttt tttttgtatt ttaacattga tcattaaaac taaaaacata gatgaaaata
     8281 ttaaaaaaga tttttcaagt aatagtaaag ataattaacc attgtgtgcc agttgatagt
     8341 agatcattgt attttattcc tcatcctaat tgtagaacag ataaatatga tattataaat
     8401 tattcgtcag ataatgttct cgttctgtta aattatttgc taaaaaaaga tagtgctgaa
     8461 tattataaaa tatatgttga aatttatgat tcttctcgta tttcagaata tcaagaatat
     8521 atttatggca taaatcctaa tattaggtgt acttttttat gtgcatgtgt tggacgtttt
     8581 ttctttaata aagtatcttt taaggatatg ttgtatgcct ttttttgttt ttgtagagca
     8641 agtaaatgtt ttacagctac tttttattat gatttttcat ttaaaaaacg ctctcaacag
     8701 attatttgtt tggggtatta tactccattc aaagatgatt atcatatggg agatcattct
     8761 tatgataaat ttcgtaatac aacatgtaac tcatttgatt actctattgc tacttcttgt
     8821 ttaagtgcta gaataatttc aatagattgt ggaatctcat atgataaatt caaagtctta
     8881 ggatttccca gaaatgattt gttgatatcg aaaaataatt gcaatgttat taaaagagaa
     8941 atttcgaaat ttgcgggata tgatgtaact aaatatatag tttatactcc aacttttcgt
     9001 gattatgaga ctgttactga aggtaatttg cgttcaatac tcggatatgt tgattgtgat
     9061 ttgttgaagt tatcgaaaat actattgaag tttaatgcgg ctttaattct taaattacat
     9121 cctttgcaga ataaaacagt cttaaaaaaa gatttaccca aaggtatact tgtttttgaa
     9181 caaacatata aatatggatt gtatgatctt ttgtcatttt cagatggaat gattactgat
     9241 tatacttcta cctattttga ttttttattg gtaaataagc cagtcatatt taatttctac
     9301 gatattgaag aatatcgtag agtaagaggt ttctcatttg agccaataga atttttttgt
     9361 gcaggtgata ttgtttacaa ttataatgaa ttgatagatg ctgtgatggg acttctggct
     9421 gggaaagata ttcatgctga acatcgacgt catatttctt tattgatgaa tcaatttcaa
     9481 gatgataatt caacaaagag aatatgtgac atatttttaa atgaaatata ataaataaaa
     9541 tgaattatgc atttgtggtg caggcacgtt taggttctac acgtttgcct ggaaaaatat
     9601 tgaaaccttt ctatggtaat caatcgattc ttgacttaat ggttcataag ctttctgcta
     9661 tatcgaatat tccagtaatt attgctacaa caaattctgt tatcaatgaa cctattgaaa
     9721 agaaggcact tgcattaggg gtaaagtgct tcagaggtga ggagaatgat gttttaaaac
     9781 gattcattga tgttgctgaa tattttgata tacagggtat attccgaata tgttctgata
     9841 atccattttt agatgtacat gcggcaaggc aattggtcga aatagcaatg aaatcttgta
     9901 acgattatat aagttttgat attgatggta ctccatcaat taaaactcat ttcggttttt
     9961 ggggagaatt tgtaacgctt gatgcgctga agcgagttat aggatttact gatgatttat
    10021 tgtatcgtga acatgttact aattatatat atagtcatcc tgaacttttt aatattcaat
    10081 ggatttcagg atctccagtc gtgtcaaaac atcataatat tcgactcacg attgatacgt
    10141 tagaagattt ttctgtagca cagagaatat atagggattt acaagaaaaa agagtggaaa
    10201 tatcgataga agtgattgta gactatgttc gaagacatgc agaatacatt caactgatga
    10261 aacaacaaat aaaaaaaaat tctaaataat gaagaatact tatattattg gtgaaatagg
    10321 gcagaatcat aatggttctg ttgacttggc taagttgatt attgaattaa tctcacgacc
    10381 tgtacatgag gatgtttttg gtatggattt catgccaatg aatgctgtta aaatgactaa
    10441 aagagattta tcagaagaat tggctgtttc tcaaatgaat caaatatatg acaatcctaa
    10501 ttcttttggg cgtacttatg gtgaacatcg tgcttttctt gagcttgatg atcaagcgca
    10561 ttttgagatt tataaatatg ctaagtcatt aggattagat tttatcgaga cgttatgtgc
    10621 caaaggatgt ctgtctttgc ttaaactgtt cacaccggat aggctaaaag ttgctagtcg
    10681 tgatttgact aacttaccat tgcttgaagc attagcagaa actcatattc ctattatatt
    10741 atcgacagga atggctggtc aaagagaact tgacaatgca ttagatgtga taacgagata
    10801 tcatagtaat atagctattc tacattgtgt atctcagtat ccaactcatc caaataattt
    10861 gaatctacgt acaataacat atttgaagaa gcattacaat aagtttgaga taggtttttc
    10921 tgatcataca ataggtattt ctgctgctac agctgctgta gcgatgggag cggaaattat
    10981 agaaaagcat gtaacaattg atcggcatat gaaaggaaca gaccagcttg gctctttagg
    11041 tccagatggg gttaatcgta tgattcgaga tattcgcata gcagagtgtt ggcttggtac
    11101 tgaagatctt tatatagaaa aaggggtgga gaagtctaag ataaaacttg aacgttctat
    11161 tgccactcga aaatatattc cagcaggtag tattattcaa gagtcggaca ttcatttact
    11221 gagtcctggt gatggttata aatggataga taaaaaaaat gtaattggtc attttgctaa
    11281 acaagatata tcagcgaatg aaataatata tcctgatttt attgaataga tatattccta
    11341 ctgcaacttg tattacggta tagagtactg cctgctataa gctaagtagt gattaataaa
    11401 taagggtaaa atactaaaaa aatgaaagag ataaagctta tacttacaga tattgatggc
    11461 gtttggactg atggcggaat gttttatgat c
//
