LOCUS       gnlProkkaDKBDKLKA_30   11692 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKBDKLKA_30.
ACCESSION   gnlProkkaDKBDKLKA_30
VERSION     gnlProkkaDKBDKLKA_30
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:49:59
            Original ID  :: gnl|Prokka|DKBDKLKA_30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11692
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11692
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2378:6692]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2379..6692
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11692
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11692
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..1156
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 46.6;
                     E-value: 3.2e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLAL
                     MKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRI
                     DVSRRIKNPRSIADNDTIGQMYTFSLKDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQN
                     VAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVI
                     RLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTV
                     TINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQI
                     EPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             1167..2315
                     /locus_tag="ctg30_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             2379..3098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.7e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3119..4420
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             4437..5561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.8e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5571..6692
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg30_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.2e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5661..6668
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg30_6_Aminotran_5.1"
                     /locus_tag="ctg30_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6689..6832
                     /locus_tag="ctg30_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             7035..8519
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.3e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8473..9732
                     /locus_tag="ctg30_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSDRIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9741..10490
                     /locus_tag="ctg30_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             10490..11530
                     /locus_tag="ctg30_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 tgaagctcag ggtctgaccg gtgacgcttt cctgaatcgt gccgtccttt atcgccagcg
       61 tgaggatttg accagtgaag ttgttcagat agacatcaag tctatcatgg acggtacttc
      121 cccgaacctt gccctgatga agaatgacat cctttacatt ccgagcattc acgatctgga
      181 agatcgtggc aatgtcacag ttcacggtga agtcgcgcac cctgattcct atccctatgc
      241 tgataacatg acacttgagg acctgatcat ccaggccggt ggcttgaaag aagctgcttc
      301 tactgtccgc attgatgtgt cgagacgaat caagaatccc cgtagtatcg cggataatga
      361 tactatcggt cagatgtata ccttctcttt aaaggatggt tttgtcatcg acggtcagcc
      421 cggttttatc cttcagcctt atgacgaagt ttatgtccgt cgcagtcctg gctatcaggc
      481 acaacagaat gtagccattg aaggtgaaat ccttttcgga ggaaattacg ccatgaccag
      541 ccgtgaggaa cgtctttccg atttagtgaa taaagccggc ggtccgacca attatgccta
      601 tctgcgtggt gcgaaactga cccgtgtggc taacgctagt gaaaagaaac gtatgggtga
      661 tgtaattcgc cttatgagca ggcaattggg cgaagccatg attgactctt tgggtattcg
      721 tgttgaagat acttttacgg ttggaataga tttggaaaaa gccttgagca atcctaaaag
      781 taatgccgat cttgtcttac gtgaaggtga tgtgatctcc atacctaaga atactaatac
      841 tgtaactatc aatggtgctg tcatggttcc gaatacggtt tcttatatga agggaaagaa
      901 tgtggattat tacctgaatc aggccggtgg ctgttctgat aatgcaagga agagtaagaa
      961 gttcattgtt tacatgaatg gtcaggtgac gaaggttaag ggtagtggta agaaacagat
     1021 tgagccgggg tgtgagatta ttgtgcctgg taaggctaag aagaaaggga acatagctaa
     1081 tattttaggt tatgctactt ccttcagttc tttgggaatg atgattgctt ctattgctaa
     1141 tttgataaag aaataaatga cctattatga ttgaaaagca atcttatcaa gaaccgtttt
     1201 ctgaagtgga taaaaggaaa gatgatgaaa tggaaataga cttgatggct attttttata
     1261 agattattac tgttcgtgga gtactatgca aagctgctgg agtgggagta ataattgcta
     1321 tagtggtggc attgagcatt cccaagcaat atacagtaaa ggttaccctt tctcctgaaa
     1381 tgggtaatgc gaagggaagt aatggtttag ccggacttgc tgcctcgttt ttgggagatg
     1441 gggctctaat aggggaaagc acagatgcct tgaacgcttc tctttcagca gatattgttt
     1501 cttcaactcc ttttttattg gaacttttag aaatggaagt ctccgtttct aaaaaggatg
     1561 ataaaatgac tttggggtct tatctcgatg aagagtcatc tccttggtgg gattatctta
     1621 taggttttcc gggcatagta ataggaggag ttaaatcatt attcggagaa gatacggttc
     1681 ctgccagtgg agggcggcaa ggaactatcg aattgacgaa agaagtaaat gagaagatta
     1741 attttcttaa aaagaagatt agtgcatcca ttgataagaa aaccgccata acgagcatta
     1801 cggtcacctt acaaaatccg cagatcactg cggttatagc agattctgtc gttcataaat
     1861 tacaggaata tattattggg tatcgaactt caaaagtaaa agaagactgt gcgtatttgg
     1921 aacggttgtt taaagaacgt cagcaggaat attatgctgc tcaaagaaaa tatgcggatt
     1981 atgtagacgc ccatgataat gtggttcttc aaagtgtacg tgctgagcag gagcgtttac
     2041 agaacgacat gagtttggct tatcagatat atagtcaggt tgctaatcag ttgcaggtat
     2101 ccagagccaa agtacaggag gaaaagccag tctttgcagt agttgagcct gccgttgtac
     2161 ctttgaaacc ttcaggtatg ggactcaaaa tttatatttt attatttgtg ttcctgtccg
     2221 tatctggtac tctcgtgtgg gtgttttttg gcaaaagtct gctggctagc ttgagaaaag
     2281 aactgaaaaa taaggagata gaacaggata aatgatgcta aaacgtcgtt tacaacattc
     2341 ttacatcaat taaattcact tactatatta ttaaacgaat gatacgtaca gctatgataa
     2401 tggctgcggg catgggaacc cgttttggcc aatatacaga attgatacct aaagggttcg
     2461 tcaaagtggg aggtattcca atgatagttc gttctattga tactttgtta tcatgtgaca
     2521 ttgagcgaat tgtaatcggt acaggatata aacaagaagt ttatgaagaa ttgaagacag
     2581 actatcctat gcttgaaacc tgttttagtc ctcgttatgc tgaaacaaat agtatgtata
     2641 ctttatataa tacgcgggag attctgggca atgatgattt tttattgtta gagtcagatt
     2701 tgatttttga gaaacaagca ataatgagct tattggagtg tcctgcggca gatgcaatgc
     2761 taataactcc agtgacaaag tttcaagatc agtattatgt ggaacatgat gataattttc
     2821 gcctttcttc atgttctgtc aataagaata aactaaacgc taaaggcgaa ttggtcggca
     2881 tccataaact atccggttcc ttttacaaaa taatgtgtgc tgattatgcg agtattgttg
     2941 atgaacaacc caatttggga tatgagtatg aattactacg aatatcttgt tctcaatctc
     3001 ctgtttatgt gcataaagta gaagggctga aatggtatga aatcgatgac atatcagatt
     3061 tggaatatgc agagaaatat attgttccgt attgttaatt aaaataatat atcaaattat
     3121 gagtaagaca gtttatattg ggatgactgc ggatattatg catccaggac ttatccgcat
     3181 tattaatgag gctactaaat acggtgatgt tataattggt cttcttacag ataaagctat
     3241 tgcggagcat aaacgccttc cttatctgac ctatgaacaa cgaaaagagg tagttcagaa
     3301 tattaaaggc gtatgtaaag ttgttcctca agaagaatgg agctatgttg agaatctcaa
     3361 acgcattaaa cctgactata taattcatgg tgacgactgg aaaaccgggc ctttacgtga
     3421 agaacgtgtg cgcgtatttg aagtgatgaa tgaacaggga ggaaaggtta tcgaaattcc
     3481 atatactttg ggaattaatt catcttcttt ggataaagat attaaggcta taggtacaac
     3541 ccctgatgta cgtttaaaat cacttcgtcg tttgataaat gccaaacccg tagttcgtat
     3601 tttggaagct catgatggac tatgtggctt gataattgaa aatcaggaaa tattaaaagg
     3661 ggataagagg gaagtatttg acggaatgtg gtctagtagc cttacggatt caaccagtaa
     3721 aggtaaacct gatattgagg cggttgattt aactacccga ttgcaagatt tgaataatat
     3781 tctggagtgt actactaaac ctattatttt tgatggagat acaggtggta aaattgaaca
     3841 tttcgtattt acagtacgca ctttagaacg tcatggaatt tcagctataa taattgaaga
     3901 taaagttgga ttaaaaaaga attcattgtt tggtacagat gttattcaaa ctcaagatac
     3961 aatcgaaggt ttctgtaata agatcaaagc aggaaaggca tctcagatta ctgatgattt
     4021 tatgattatc gctcgtattg agagccttat agcgggaaag ccggtaagtg atgctttaga
     4081 gagagctttt gcatatgtcc aagcgggagc ggacggtatt atgatacata gcaaaaataa
     4141 gtcgggtgaa gatataaaag aattttgttt ggcgtttcga aaacagtatg ctcatgtacc
     4201 tatcgtggtt gtgcctacta catatgatca tatttatgag tctgaattgt gtgattgggg
     4261 tgtgaatata attatttatg ctaatcatat gcttcgtgcc gcttatcctg ctatgatgaa
     4321 tgtcgcaaag ataatattag agaatgaacg tgctttagag gtgcgcgaac tgtgtatgcc
     4381 cataaaagaa atattggaac tgattccagg tactaaataa aaagaggaat atcattatgt
     4441 taagcgtaga aaaagtttat gaaacgtttc tgagtcatga cgttgatttt tttacaggag
     4501 ttccagactc attactaaaa aatatttgtg cctatatcac agaccatact tcacgtgaga
     4561 aacatatcat agctgctaat gaaggtgcgg ctgtaggaat tgcttcaggt tattatatgg
     4621 catcaggtaa ggttcctgtg gtttatatgc aaaattccgg cttgggtaat actgttaatc
     4681 ctctgctgtc tcttgcagat gaacaagtat acagttttcc aatgcttttg atgattggct
     4741 ggcgtggtga accgggaaca aaagatgaac ctcagcataa aaaacagggt gaggtaactt
     4801 tagatttgtt gaaagcaatg cggattcctt atataattct tgattcaaat gagaatgatg
     4861 catttattca gctccatgat atcatacaat cagcaaaaac taagaatatt cctcatgcaa
     4921 taattattcg gaaagatgtt tttggcaaat ataaacttca aaaagagttc ggatgtaatt
     4981 atcctttatc tcgtgaggat gctttgcaaa tagttgtgga ttatctgcct gaaaattcag
     5041 tggtcgtttc tactactggc aagctttctc gtgagttatt tgaatatcga gaaatgaaag
     5101 agcaaggtca tgaacatgat tttctcacgg taggctctat gggacatagt tcatcaatct
     5161 ctttgggtat tgctatagca aagcaagata gacctgttta ttgcttggat ggtgatggag
     5221 catttattat gcatttaggg gcaattagta acattggcga tttatctcct aaaaactatt
     5281 atcatatttt gtttaacaat ggtgctcacg agtctgtagg aggacagcct actttaggat
     5341 ttagtttaga tattccggct attgtccggg ggagcggata taagcatact tatactgttt
     5401 gtacaaaagt tgaaattgaa gaagcaatga agcagcttcc aaagttatgt ggtcctgttt
     5461 tgttggaaat aaaggttaaa atagattctc gggagaattt gggacgtccc acgactactc
     5521 ctatagagaa taaggagcat tttatggatt ttttaaaata aatatattcg atgaaaatag
     5581 aaagaaaaat attattaaat cctgggcctg ccactactac tgacagtgta aaaatggcac
     5641 aagttgttcc ggatatttgt cctcgcgaga aagaattcgc aggtatgatg aaacaacttc
     5701 gggacgattt ggtcagagtt gctcatggga atttggaaaa acataccgct gtattatttt
     5761 gtggctcagg aaccatcaat attgatatat gtctaaattc tcttcttcct gaagacaaaa
     5821 gggtgcttat agtgaataat ggggcatata gtacccgtgc tgtagaagtg tgtcaatatt
     5881 atggtttgcc tcatattaat ttggaatttt ccgtttacga acgtcctgat ttatcggtgg
     5941 tggaaaatgt gttgcaagaa aatcctgata tagctatggt ttatactact catcacgaga
     6001 cgggtacagg aattctgaac cctattcgcg agatgggcgc tatagctcat aaatatcagg
     6061 ctaaatttgt cgtcgatact acttcttctt tgggcatgat tccttttgat atagagaaag
     6121 ataatgtgga tttttgtatg gcatctgctc aaaaaggact tcaagcgatg acaggtcttt
     6181 cttttattat aggcaatgag gaacagatta agttttcaaa aaaatatccc aagcgttctt
     6241 actattgtaa tctttatttg cagtatgaga attttgagag aacaggtgaa atgcatttta
     6301 ctccaccggt acaaactatt tacgccactc gtcaggcatt aaatgaatat tttgaagtgg
     6361 gtgaagaagc taagtttgcc cgtcacaaaa gagtttttga ggctattcat tcaggtataa
     6421 atgaaattgg tcttaaaagt gtaataaagc gtgaatggca gtcaggactg gttgtctcag
     6481 ttcaataccc agaagatccc aactgggatt ttgagaaaat acatgattat tgttatgagc
     6541 gtggatttac gatttatcca ggtaagatat caactgagga tacttttaga atctgtgctt
     6601 taggagagat agaagtagat gatattgaga acttctttaa agtactaaaa gctgcattaa
     6661 atcattataa cgtcacatta ccgatgtcat gattgcagaa atattattga agattcgtca
     6721 tttttatttt tcccttcgtg gtatacactt ccatccggaa agtgttattt ctggagtgcc
     6781 tattcgtagc tttcgcttag taggcaaata tggcaatatt aatttgaggt gatgcattag
     6841 gagttcttta ttcttataaa aaggcatcgg tagttatagg agataatgtt tgtgtagggt
     6901 aatttgcttt tagtgggaga gaccatatta gaattgcggt aaggggcgaa gaagataata
     6961 accaattagt gagaatattg gaaaaatata attgatatcg gtaaatgtag ttgtttttat
     7021 actgtattta agtaatggaa aatctaaagc agaaaactgt atcaggaata atgtggagcg
     7081 ctatagaacg tttctcttta caaggagtac agtttataat tcaaataata ttagctcgtt
     7141 tgttactacc atcggattat ggtatgatcg ggatgttagc tatttttctt caagtcgctc
     7201 aagtatttat agatagcggt tttacaaatg ctttaatcca gaaaaaagat agaactgaag
     7261 aggattttgc cactgtcttt tattttaata ttcttgtcgc agtattattc tatggtatat
     7321 tgtttttttc ggcttctttg attgcagact tttataatat gccgacttta gttcttgtaa
     7381 ttcgttttat agcattgtcg ttgataataa atgctttatc ggctattcac agaacgaaat
     7441 taattatttc tgtaaacttt aaaactcaat ctaaaatttc attaggtgca gcttttatat
     7501 caggcgtgat tggaatatgg atggcttatg tcggttgcgg ggtttgggct ttagtttggc
     7561 aaactctctt aaatagtata attttgacaa ttttgtttta ctgtttagtt cattggaaac
     7621 ctttacatac tttctccaaa agttcttttg aaagattatt caatttcgga tctaaattat
     7681 tgatctcaag tcttatcaat acagtatatc gtaatctgta taccattgta ataggaaaaa
     7741 agttttctgt tgtagagctt ggttactata caagagcaga acaatttgct atttttcctt
     7801 ccaataattt aaatgcttta gtttctagag tagcgtatcc tattttaagt tccattcaag
     7861 atgatgataa atgtttaaca aacgcatatc gaaattatat cagattatcc tcatatataa
     7921 tttttccttt aatggtaggt ttacttgttt tggctaatcc tattattagt ctattgttaa
     7981 cagataaatg gtctggggtt gttattcttt tacagatatt atgtttggat tggatgtttg
     8041 atcatttgag ccaaattaat ttgaatttat tatgggttaa aggaagatct gatctgtcgt
     8101 tacgtcttga aataataaaa aagacgattg ctatattcat tctttttgtg tcaattccat
     8161 ttgggcttga ggtgatgtgt tggggtagag ttatttactc tctgatagcg acatatttga
     8221 atacatatta tactaattct cttattgatt tgaccttaaa gttgcaagtt aaagatgtat
     8281 ttccaagttt aatactctct ttcataatgg gggggatcgt ttttatatgt atttctttct
     8341 ttgaaactga tatagtaaaa attgtgattg gatgtattac tgggatgtcc ttctatattt
     8401 tactttcttt tctttttaag ctagattctt ttttttgtat tttaacattg atcattaaaa
     8461 ctaaaaacat agatgaaaat attaaaaaag atttttcaag taatagtaaa gataattaac
     8521 cattgtgtgc cagttgatag tagatcattg tattttattc ctcatcctaa ttgtagaaca
     8581 gataaatatg atattataaa ttattcgtca gataatgttc tcgttctgtt aaattatttg
     8641 ctaaaaaaag atagtgctga atattataaa atatatgttg aaatttatga ttcttctcgt
     8701 atttcagaat atcaagaata tatttatggc ataaatccta atattaggtg tactttttta
     8761 tgtgcatgtg ttggacgttt tttctttaat aaagtatctt ttaaggatat gttgtatgcc
     8821 tttttttgtt tttgtagagc aagtaaatgt tttacagcta ctttttatta tgatttttca
     8881 tttaaaaaac gctctcaaca gattatttgt ttggggtatt atactccatt caaagatgat
     8941 tatcatatgg gagatcattc ttatgataaa tttcgtaata caacatgtaa ctcatttgat
     9001 tactctattg ctacttcttg tttaagtgat agaataattt caatagattg tggaatctca
     9061 tatgataaat tcaaagtctt aggatttccc agaaatgatt tgttgatatc gaaaaataat
     9121 tgcaatgtta ttaaaagaga aatttcgaaa tttgcgggat atgatgtaac taaatatata
     9181 gtttatactc caacttttcg tgattatgag actgttactg aaggtaattt gcgttcaata
     9241 ctcggatatg ttgattgtga tttgttgaag ttatcgaaaa tactattgaa gtttaatgcg
     9301 gctttaattc ttaaattaca tcctttgcag aataaaacag tcttaaaaaa agatttaccc
     9361 aaaggtatac ttgtttttga acaaacatat aaatatggat tgtatgatct tttgtcattt
     9421 tcagatggaa tgattactga ttatacttct acctattttg attttttatt ggtaaataag
     9481 ccagtcatat ttaatttcta cgatattgaa gaatatcgta gagtaagagg tttctcattt
     9541 gagccaatag aatttttttg tgcaggtgat attgtttaca attataatga attgatagat
     9601 gctgtgatgg gacttctggc tgggaaagat attcatgctg aacatcgacg tcatatttct
     9661 ttattgatga atcaatttca agatgataat tcaacaaaga gaatatgtga catattttta
     9721 aatgaaatat aataaataaa atgaattatg catttgtggt gcaggcacgt ttaggttcta
     9781 cacgtttgcc tggaaaaata ttgaaacctt tctatggtaa tcaatcgatt cttgacttaa
     9841 tggttcataa gctttctgct atatcgaata ttccagtaat tattgctaca acaaattctg
     9901 ttatcaatga acctattgaa aagaaggcac ttgcattagg ggtaaagtgc ttcagaggtg
     9961 aggagaatga tgttttaaaa cgattcattg atgttgctga atattttgat atacagggta
    10021 tattccgaat atgttctgat aatccatttt tagatgtaca tgcggcaagg caattggtcg
    10081 aaatagcaat gaaatcttgt aacgattata taagttttga tattgatggt actccatcaa
    10141 ttaaaactca tttcggtttt tggggagaat ttgtaacgct tgatgcgctg aagcgagtta
    10201 taggatttac tgatgattta ttgtatcgtg aacatgttac taattatata tatagtcatc
    10261 ctgaactttt taatattcaa tggatttcag gatctccagt cgtgtcaaaa catcataata
    10321 ttcgactcac gattgatacg ttagaagatt tttctgtagc acagagaata tatagggatt
    10381 tacaagaaaa aagagtggaa atatcgatag aagtgattgt agactatgtt cgaagacatg
    10441 cagaatacat tcaactgatg aaacaacaaa taaaaaaaaa ttctaaataa tgaagaatac
    10501 ttatattatt ggtgaaatag ggcagaatca taatggttct gttgacttgg ctaagttgat
    10561 tattgaatta atctcacgac ctgtacatga ggatgttttt ggtatggatt tcatgccaat
    10621 gaatgctgtt aaaatgacta aaagagattt atcagaagaa ttggctgttt ctcaaatgaa
    10681 tcaaatatat gacaatccta attcttttgg gcgtacttat ggtgaacatc gtgcttttct
    10741 tgagcttgat gatcaagcgc attttgagat ttataaatat gctaagtcat taggattaga
    10801 ttttatcgag acgttatgtg ccaaaggatg tctgtctttg cttaaactgt tcacaccgga
    10861 taggctaaaa gttgctagtc gtgatttgac taacttacca ttgcttgaag cattagcaga
    10921 aactcatatt cctattatat tatcgacagg aatggctggt caaagagaac ttgacaatgc
    10981 attagatgtg ataacgagat atcatagtaa tatagctatt ctacattgtg tatctcagta
    11041 tccaactcat ccaaataatt tgaatctacg tacaataaca tatttgaaga agcattacaa
    11101 taagtttgag ataggttttt ctgatcatac aataggtatt tctgctgcta cagctgctgt
    11161 agcgatggga gcggaaatta tagaaaagca tgtaacaatt gatcggcata tgaaaggaac
    11221 agaccagctt ggctctttag gtccagatgg ggttaatcgt atgattcgag atattcgcat
    11281 agcagagtgt tggcttggta ctgaagatct ttatatagaa aaaggggtgg agaagtctaa
    11341 gataaaactt gaacgttcta ttgccactcg aaaatatatt ccagcaggta gtattattca
    11401 agagtcggac attcatttac tgagtcctgg tgatggttat aaatggatag ataaaaaaaa
    11461 tgtaattggt cattttgcta aacaagatat atcagcgaat gaaataatat atcctgattt
    11521 tattgaatag atatattcct actgcaactt gtattacggt atagagtact gcctgctata
    11581 agctaagtag tgattaataa ataagggtaa aatactaaaa aaatgaaaga gataaagctt
    11641 atacttacag atattgatgg cgtttggact gatggcggaa tgttttatga tc
//
